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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3093998
log Bayes Factor = 77.8519
Chromosome 6   position 31,485,174  (GRCh37) Explore rs3093998 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
E14 Unspecified diabetes mellitus
0.000 0.003 0.997
E10.4 With neurological complications
0.000 0.007 0.993
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.011 0.989
E10.1 With ketoacidosis
0.000 0.019 0.981
E14.3 With ophthalmic complications
0.000 0.019 0.981
L40.9 Psoriasis, unspecified
0.977 0.023 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.031 0.969
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.040 0.960
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.044 0.956
E10.2 With renal complications
0.000 0.050 0.949
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.054 0.946
E16 Other disorders of pancreatic internal secretion
0.000 0.068 0.932
E11 Non-insulin-dependent diabetes mellitus
0.000 0.070 0.930
E11.9 Without complications
0.000 0.078 0.922
E13 Other specified diabetes mellitus
0.000 0.108 0.892
E16.2 Hypoglycaemia, unspecified
0.000 0.120 0.880
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.122 0.878
L40 Psoriasis
0.869 0.131 0.000
E14.8 With unspecified complications
0.000 0.132 0.868
E06 Thyroiditis
0.000 0.139 0.861
E10.8 With unspecified complications
0.000 0.154 0.846
E07 Other disorders of thyroid
0.000 0.159 0.841
E11.0 With coma
0.000 0.164 0.836
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.168 0.832
L40.0 Psoriasis vulgaris
0.825 0.175 0.000
E13.9 Without complications
0.000 0.191 0.809
E14.6 With other specified complications
0.000 0.193 0.807
E14.2 Withrenal complications
0.000 0.194 0.806
E10.0 With coma
0.000 0.197 0.803
E14.9 Without complications
0.000 0.201 0.799
E16.1 Other hypoglycaemia
0.000 0.212 0.788
E10.6 With other specified complications
0.000 0.225 0.775
E06.3 Autoimmune thyroiditis
0.000 0.246 0.754
L40.1 Generalised pustular psoriasis
0.747 0.253 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.255 0.745
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.255 0.745
E14.1 With ketoacidosis
0.000 0.263 0.737
K90 Intestinal malabsorption
0.000 0.263 0.737
E14.5 With peripheral circulatory complications
0.000 0.264 0.736
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.264 0.736
E14.4 With neurological complications
0.000 0.265 0.735
E10.5 With peripheral circulatory complications
0.000 0.273 0.727
M06 Other rheumatoid arthritis
0.000 0.274 0.726
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
G35-G37 Demyelinating diseases of the central nervous system
0.715 0.285 0.000
E14.7 With multiple complications
0.000 0.285 0.715
E14.0 With coma
0.000 0.285 0.715
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.298 0.702
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.306 0.694
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.310 0.690
E15 Nondiabetic hypoglycaemic coma
0.000 0.312 0.688
E05.8 Other thyrotoxicosis
0.000 0.315 0.685
E11.1 With ketoacidosis
0.000 0.331 0.669
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.332 0.668
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.332 0.668
E16.4 Abnormal secretion of gastrin
0.000 0.332 0.668
E16.3 Increased secretion of glucagon
0.000 0.332 0.668
K90.9 Intestinal malabsorption, unspecified
0.000 0.333 0.667
E11.7 With multiple complications
0.000 0.333 0.666
E06.9 Thyroiditis, unspecified
0.000 0.335 0.665
G37 Other demyelinating diseases of central nervous system
0.662 0.338 0.000
E13.3 With ophthalmic complications
0.000 0.341 0.659
E40-E46 Malnutrition
0.000 0.349 0.650
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.356 0.643
L40.3 Pustulosis palmaris et plantaris
0.643 0.357 0.000
E11.6 With other specified complications
0.000 0.358 0.642
M06.4 Inflammatory polyarthropathy
0.000 0.359 0.641
E13.8 With unspecified complications
0.000 0.360 0.640
E13.7 With multiple complications
0.000 0.360 0.640
E13.6 With other specified complications
0.000 0.360 0.640
E13.5 With peripheral circulatory complications
0.000 0.360 0.640
E13.4 With neurological complications
0.000 0.360 0.640
E13.2 With renal complications
0.000 0.360 0.640
E13.1 With ketoacidosis
0.000 0.360 0.640
E13.0 With coma
0.000 0.360 0.640
E03.1 Congenital hypothyroidism without goitre
0.000 0.362 0.638
M06.3 Rheumatoid nodule
0.000 0.374 0.626
L40.4 Guttate psoriasis
0.623 0.377 0.000
L40.2 Acrodermatitis continua
0.623 0.377 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.382 0.618
G37.9 Demyelinating disease of central nervous system, unspecified
0.618 0.382 0.000
E06.5 Other chronic thyroiditis
0.000 0.382 0.618
E06.4 Drug-induced thyroiditis
0.000 0.382 0.618
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.382 0.618
E06.0 Acute thyroiditis
0.000 0.382 0.618
L40.5 Arthropathic psoriasis
0.607 0.393 0.000
E07.1 Dyshormogenetic goitre
0.000 0.397 0.603
E07.0 Hypersecretion of calcitonin
0.000 0.397 0.603
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.409 0.591
E06.1 Subacute thyroiditis
0.000 0.419 0.581
K90.8 Other intestinal malabsorption
0.000 0.420 0.580
M06.34 Rheumatoid nodule (Hand)
0.000 0.420 0.580
E50-E64 Other nutritional deficiencies
0.000 0.424 0.576
L40.8 Other psoriasis
0.561 0.438 0.000
E07.8 Other specified disorders of thyroid
0.000 0.440 0.559
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.456 0.544
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.458 0.542
K90.3 Pancreatic steatorrhoea
0.000 0.472 0.528
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.472 0.528
K90.1 Tropical sprue
0.000 0.472 0.528
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.473 0.527
M06.2 Rheumatoid bursitis
0.000 0.479 0.520
M06.1 Adult-onset Still's disease
0.000 0.479 0.520
G37.8 Other specified demyelinating diseases of central nervous system
0.519 0.481 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M06.8 Other specified rheumatoid arthritis
0.000 0.492 0.508
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.493 0.507
G36 Other acute disseminated demyelination
0.496 0.504 0.000
E11.8 With unspecified complications
0.000 0.508 0.492
E11.3 With ophthalmic complications
0.000 0.510 0.490
E11.2 With renal complications
0.000 0.513 0.487
G37.5 Concentric sclerosis [Balo]
0.475 0.525 0.000
G37.4 Subacute necrotising myelitis
0.475 0.525 0.000
G37.2 Central pontine myelinolysis
0.475 0.525 0.000
G37.1 Central demyelination of corpus callosum
0.475 0.525 0.000
G37.0 Diffuse sclerosis
0.475 0.525 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.533 0.466
E45 Retarded development following protein-energy malnutrition
0.000 0.533 0.466
E43 Unspecified severe protein-energy malnutrition
0.000 0.533 0.466
E42 Marasmic kwashiorkor
0.000 0.533 0.466
E41 Nutritional marasmus
0.000 0.533 0.466
E40 Kwashiorkor
0.000 0.533 0.466
E65-E68 Obesity and other hyperalimentation
0.000 0.538 0.462
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.540 0.460
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.540 0.460
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.540 0.460
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.540 0.460
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.540 0.460
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.540 0.460
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.540 0.460
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.540 0.460
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.450 0.550 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.551 0.449
M06.38 Rheumatoid nodule (Other)
0.000 0.551 0.449
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.551 0.449
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.551 0.449
M06.33 Rheumatoid nodule (Forearm)
0.000 0.551 0.449
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.551 0.449
E58 Dietary calcium deficiency
0.000 0.558 0.442
M06.0 Seronegative rheumatoid arthritis
0.000 0.560 0.439
E51 Thiamine deficiency
0.000 0.565 0.435
E11.4 With neurological complications
0.000 0.567 0.433
E11.5 With peripheral circulatory complications
0.000 0.571 0.429
E61 Deficiency of other nutrient elements
0.000 0.572 0.428
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.576 0.424
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.577 0.422
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.586 0.414
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.587 0.413
E63 Other nutritional deficiencies
0.000 0.587 0.413
E50 Vitamin A deficiency
0.000 0.587 0.413
E60 Dietary zinc deficiency
0.000 0.587 0.413
E59 Dietary selenium deficiency
0.000 0.587 0.413
E54 Ascorbic acid deficiency
0.000 0.587 0.413
E52 Niacin deficiency [pellagra]
0.000 0.587 0.413
E46 Unspecified protein-energy malnutrition
0.000 0.599 0.401
E56 Other vitamin deficiencies
0.000 0.604 0.396
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.627 0.373
M06.18 Adult-onset Still's disease (Other)
0.000 0.627 0.373
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.627 0.373
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.627 0.373
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.627 0.373
M06.14 Adult-onset Still's disease (Hand)
0.000 0.627 0.373
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.627 0.373
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.627 0.373
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.627 0.373
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.627 0.373
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.627 0.373
M06.28 Rheumatoid bursitis (Other)
0.000 0.627 0.373
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.627 0.373
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.627 0.373
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.627 0.373
M06.24 Rheumatoid bursitis (Hand)
0.000 0.627 0.373
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.627 0.373
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.627 0.373
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.627 0.373
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.627 0.373
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.636 0.364
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.636 0.364
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.636 0.364
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.636 0.364
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.636 0.364
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.636 0.364
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.636 0.364
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.636 0.364
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.636 0.364
G36.9 Acute disseminated demyelination, unspecified
0.355 0.644 0.000
G36.8 Other specified acute disseminated demyelination
0.355 0.644 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.355 0.644 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.648 0.352
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.655 0.345
E55 Vitamin D deficiency
0.000 0.660 0.340
G36.0 Neuromyelitis optica [Devic]
0.338 0.661 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.665 0.334
E44.0 Moderate protein-energy malnutrition
0.000 0.665 0.334
E51.2 Wernicke's encephalopathy
0.000 0.666 0.334
E67 Other hyperalimentation
0.000 0.669 0.331
E68 Sequelae of hyperalimentation
0.000 0.669 0.331
E65 Localised adiposity
0.000 0.675 0.325
E61.1 Iron deficiency
0.000 0.675 0.325
E03.8 Other specified hypothyroidism
0.001 0.680 0.318
E83.1 Disorders of iron metabolism
0.318 0.682 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.685 0.315
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.685 0.315
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.685 0.315
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.685 0.315
E51.9 Thiamine deficiency, unspecified
0.000 0.688 0.312
E51.8 Other manifestations of thiamine deficiency
0.000 0.688 0.312
E51.1 Beriberi
0.000 0.688 0.312
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.689 0.310
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.691 0.309
E61.9 Deficiency of nutrient element, unspecified
0.000 0.693 0.307
E61.8 Deficiency of other specified nutrient elements
0.000 0.693 0.307
E61.7 Deficiency of multiple nutrient elements
0.000 0.693 0.307
E61.6 Vanadium deficiency
0.000 0.693 0.307
E61.5 Molybdenum deficiency
0.000 0.693 0.307
E61.4 Chromium deficiency
0.000 0.693 0.307
E61.3 Manganese deficiency
0.000 0.693 0.307
E61.0 Copper deficiency
0.000 0.693 0.307
E61.2 Magnesium deficiency
0.000 0.696 0.304
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.699 0.301
E50.9 Vitamin A deficiency, unspecified
0.000 0.704 0.296
E50.8 Other manifestations of vitamin A deficiency
0.000 0.704 0.296
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.704 0.296
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.704 0.296
E50.5 Vitamin A deficiency with night blindness
0.000 0.704 0.296
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.704 0.296
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.704 0.296
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.704 0.296
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.704 0.296
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.704 0.296
E63.9 Nutritional deficiency, unspecified
0.000 0.704 0.296
E63.8 Other specified nutritional deficiencies
0.000 0.704 0.296
E63.1 Imbalance of constituents of food intake
0.000 0.704 0.296
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.704 0.296
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.704 0.296
E64.8 Sequelae of other nutritional deficiencies
0.000 0.704 0.296
E64.3 Sequelae of rickets
0.000 0.704 0.296
E64.2 Sequelae of vitamin C deficiency
0.000 0.704 0.296
E64.1 Sequelae of vitamin A deficiency
0.000 0.704 0.296
E64.0 Sequelae of protein-energy malnutrition
0.000 0.704 0.296
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.705 0.295
E56.9 Vitamin deficiency, unspecified
0.000 0.716 0.284
E56.8 Deficiency of other vitamins
0.000 0.716 0.284
E56.0 Deficiency of vitamin E
0.000 0.716 0.284
E53 Deficiency of other B group vitamins
0.000 0.717 0.283
E56.1 Deficiency of vitamin K
0.000 0.733 0.267
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.751 0.249
E55.0 Rickets, active
0.000 0.756 0.244
E67.8 Other specified hyperalimentation
0.000 0.762 0.237
E67.3 Hypervitaminosis D
0.000 0.762 0.237
E67.2 Megavitamin-B6 syndrome
0.000 0.762 0.237
E67.1 Hypercarotenaemia
0.000 0.762 0.237
E67.0 Hypervitaminosis A
0.000 0.762 0.237
J45 Asthma
0.000 0.770 0.230
E20-E35 Disorders of other endocrine glands
0.000 0.788 0.212
E53.1 Pyridoxine deficiency
0.000 0.797 0.203
E53.0 Riboflavin deficiency
0.000 0.797 0.203
E22 Hyperfunction of pituitary gland
0.000 0.804 0.196
E04 Other non-toxic goitre
0.000 0.806 0.194
E53.9 Vitamin B deficiency, unspecified
0.000 0.812 0.188
L40-L45 Papulosquamous disorders
0.135 0.821 0.044
J45.1 Nonallergic asthma
0.000 0.824 0.176
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.824 0.176
E55.9 Vitamin D deficiency, unspecified
0.000 0.830 0.170
E70-E90 Metabolic disorders
0.000 0.839 0.161
J45.8 Mixed asthma
0.000 0.839 0.161
E83 Disorders of mineral metabolism
0.152 0.839 0.009
E22.1 Hyperprolactinaemia
0.000 0.839 0.161
E29 Testicular dysfunction
0.000 0.843 0.157
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.848 0.152
E32 Diseases of thymus
0.000 0.848 0.152
E31 Polyglandular dysfunction
0.000 0.848 0.152
E30 Disorders of puberty, not elsewhere classified
0.000 0.848 0.152
L43 Lichen planus
0.029 0.853 0.118
E25 Adrenogenital disorders
0.000 0.853 0.147
E83.3 Disorders of phosphorus metabolism
0.143 0.855 0.002
L43.9 Lichen planus, unspecified
0.001 0.856 0.144
E22.0 Acromegaly and pituitary gigantism
0.000 0.857 0.143
E23 Hypofunction and other disorders of pituitary gland
0.000 0.857 0.143
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.859 0.140
E22.8 Other hyperfunction of pituitary gland
0.000 0.859 0.140
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.860 0.140
E85 Amyloidosis
0.000 0.860 0.140
E04.8 Other specified non-toxic goitre
0.000 0.861 0.139
E20 Hypoparathyroidism
0.000 0.863 0.137
E04.9 Non-toxic goitre, unspecified
0.000 0.863 0.137
E26 Hyperaldosteronism
0.000 0.864 0.136
L41 Parapsoriasis
0.097 0.871 0.032
L45 Papulosquamous disorders in diseases classified elsewhere
0.097 0.871 0.032
E79 Disorders of purine and pyrimidine metabolism
0.000 0.872 0.128
L44 Other papulosquamous disorders
0.097 0.872 0.031
E24 Cushing's syndrome
0.000 0.874 0.126
E83.9 Disorder of mineral metabolism, unspecified
0.119 0.875 0.006
E89.3 Postprocedural hypopituitarism
0.000 0.876 0.124
E23.2 Diabetes insipidus
0.000 0.879 0.121
L43.8 Other lichen planus
0.010 0.881 0.109
E29.1 Testicular hypofunction
0.000 0.882 0.118
E74 Other disorders of carbohydrate metabolism
0.000 0.882 0.118
E23.6 Other disorders of pituitary gland
0.000 0.882 0.118
E70 Disorders of aromatic amino-acid metabolism
0.000 0.883 0.116
E89.2 Postprocedural hypoparathyroidism
0.000 0.884 0.116
E28 Ovarian dysfunction
0.000 0.884 0.116
E77 Disorders of glycoprotein metabolism
0.000 0.884 0.116
E76 Disorders of glycosaminoglycan metabolism
0.000 0.884 0.116
E72 Other disorders of amino-acid metabolism
0.000 0.884 0.116
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.884 0.116
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.884 0.116
E83.8 Other disorders of mineral metabolism
0.109 0.884 0.007
E83.2 Disorders of zinc metabolism
0.109 0.884 0.007
E83.0 Disorders of copper metabolism
0.109 0.884 0.007
E04.0 Non-toxic diffuse goitre
0.000 0.885 0.115
E85.9 Amyloidosis, unspecified
0.000 0.885 0.114
E84 Cystic fibrosis
0.000 0.886 0.114
E29.9 Testicular dysfunction, unspecified
0.000 0.887 0.113
E29.8 Other testicular dysfunction
0.000 0.887 0.113
E29.0 Testicular hyperfunction
0.000 0.887 0.113
E85.3 Secondary systemic amyloidosis
0.000 0.888 0.112
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.888 0.112
L42 Pityriasis rosea
0.075 0.890 0.035
E34 Other endocrine disorders
0.000 0.890 0.110
E30.9 Disorder of puberty, unspecified
0.000 0.890 0.109
E30.8 Other disorders of puberty
0.000 0.890 0.109
E30.1 Precocious puberty
0.000 0.890 0.109
E30.0 Delayed puberty
0.000 0.890 0.109
E31.9 Polyglandular dysfunction, unspecified
0.000 0.890 0.109
E31.8 Other polyglandular dysfunction
0.000 0.890 0.109
E31.1 Polyglandular hyperfunction
0.000 0.890 0.109
E31.0 Autoimmune polyglandular failure
0.000 0.890 0.109
E32.9 Disease of thymus, unspecified
0.000 0.890 0.109
E32.8 Other diseases of thymus
0.000 0.890 0.109
E32.1 Abscess of thymus
0.000 0.890 0.109
E32.0 Persistent hyperplasia of thymus
0.000 0.890 0.109
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.890 0.109
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.890 0.109
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.890 0.109
E85.4 Organ-limited amyloidosis
0.000 0.892 0.107
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.893 0.107
E53.8 Deficiency of other specified B group vitamins
0.000 0.893 0.107
L43.3 Subacute (active) lichen planus
0.021 0.894 0.085
L43.2 Lichenoid drug reaction
0.021 0.894 0.085
L43.1 Bullous lichen planus
0.021 0.894 0.085
L43.0 Hypertrophic lichen planus
0.021 0.894 0.085
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.894 0.106
E25.9 Adrenogenital disorder, unspecified
0.000 0.894 0.105
E25.8 Other adrenogenital disorders
0.000 0.894 0.105
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.895 0.105
E26.9 Hyperaldosteronism, unspecified
0.000 0.895 0.104
E73 Lactose intolerance
0.000 0.896 0.104
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.897 0.103
E23.1 Drug-induced hypopituitarism
0.000 0.897 0.103
E88 Other metabolic disorders
0.000 0.898 0.102
E24.2 Drug-induced Cushing's syndrome
0.000 0.899 0.101
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.899 0.101
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.899 0.101
E89.5 Postprocedural testicular hypofunction
0.000 0.899 0.101
E85.8 Other amyloidosis
0.000 0.899 0.101
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.899 0.101
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.899 0.101
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.899 0.101
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.900 0.100
E89.1 Postprocedural hypoinsulinaemia
0.000 0.901 0.099
E20.8 Other hypoparathyroidism
0.000 0.901 0.098
E20.1 Pseudohypoparathyroidism
0.000 0.901 0.098
E20.0 Idiopathic hypoparathyroidism
0.000 0.901 0.098
E89.0 Postprocedural hypothyroidism
0.000 0.902 0.098
E26.8 Other hyperaldosteronism
0.000 0.902 0.098
E26.1 Secondary hyperaldosteronism
0.000 0.902 0.098
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.904 0.096
E89.4 Postprocedural ovarian failure
0.000 0.904 0.095
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.905 0.095
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.905 0.095
E66 Obesity
0.000 0.906 0.094
L41.9 Parapsoriasis, unspecified
0.070 0.908 0.023
L41.8 Other parapsoriasis
0.070 0.908 0.023
L41.5 Retiform parapsoriasis
0.070 0.908 0.023
L41.4 Large plaque parapsoriasis
0.070 0.908 0.023
L41.3 Small plaque parapsoriasis
0.070 0.908 0.023
L41.2 Lymphomatoid papulosis
0.070 0.908 0.023
L41.1 Pityriasis lichenoides chronica
0.070 0.908 0.023
L41.0 Pityriasis lichenoides et varioliformis acuta
0.070 0.908 0.023
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.908 0.092
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.908 0.092
E79.1 Lesch-Nyhan syndrome
0.000 0.908 0.092
L44.9 Papulosquamous disorder, unspecified
0.070 0.908 0.022
L44.8 Other specified papulosquamous disorders
0.070 0.908 0.022
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.070 0.908 0.022
L44.3 Lichen ruber moniliformis
0.070 0.908 0.022
L44.2 Lichen striatus
0.070 0.908 0.022
L44.1 Lichen nitidus
0.070 0.908 0.022
L44.0 Pityriasis rubra pilaris
0.070 0.908 0.022
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.909 0.090
E24.3 Ectopic ACTH syndrome
0.000 0.909 0.090
E24.1 Nelson's syndrome
0.000 0.909 0.090
E88.2 Lipomatosis, not elsewhere classified
0.000 0.912 0.088
E80.1 Porphyria cutanea tarda
0.000 0.914 0.086
E28.3 Primary ovarian failure
0.000 0.915 0.085
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.915 0.084
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.915 0.084
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.915 0.084
E74.2 Disorders of galactose metabolism
0.000 0.915 0.084
E74.1 Disorders of fructose metabolism
0.000 0.915 0.084
E70.3 Albinism
0.000 0.915 0.084
E84.9 Cystic fibrosis, unspecified
0.000 0.915 0.084
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.916 0.084
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.916 0.084
E70.2 Disorders of tyrosine metabolism
0.000 0.916 0.084
E70.1 Other hyperphenylalaninaemias
0.000 0.916 0.084
E70.0 Classical phenylketonuria
0.000 0.916 0.084
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.916 0.084
E28.9 Ovarian dysfunction, unspecified
0.000 0.916 0.083
E28.8 Other ovarian dysfunction
0.000 0.916 0.083
E28.1 Androgen excess
0.000 0.916 0.083
E28.0 Oestrogen excess
0.000 0.916 0.083
E20.9 Hypoparathyroidism, unspecified
0.000 0.917 0.083
E71.3 Disorders of fatty-acid metabolism
0.000 0.917 0.083
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.917 0.083
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.917 0.083
E71.0 Maple-syrup-urine disease
0.000 0.917 0.083
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.917 0.083
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.917 0.083
E72.5 Disorders of glycine metabolism
0.000 0.917 0.083
E72.4 Disorders of ornithine metabolism
0.000 0.917 0.083
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.917 0.083
E72.2 Disorders of urea cycle metabolism
0.000 0.917 0.083
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.917 0.083
E72.0 Disorders of amino-acid transport
0.000 0.917 0.083
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.917 0.083
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.917 0.083
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.917 0.083
E76.2 Other mucopolysaccharidoses
0.000 0.917 0.083
E76.1 Mucopolysaccharidosis, type II
0.000 0.917 0.083
E76.0 Mucopolysaccharidosis, type I
0.000 0.917 0.083
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.917 0.083
E77.8 Other disorders of glycoprotein metabolism
0.000 0.917 0.083
E77.1 Defects in glycoprotein degradation
0.000 0.917 0.083
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.917 0.083
E34.8 Other specified endocrine disorders
0.000 0.917 0.082
E24.8 Other Cushing's syndrome
0.000 0.918 0.082
E78.5 Hyperlipidaemia, unspecified
0.000 0.918 0.082
E80.2 Other porphyria
0.000 0.918 0.082
E84.8 Cystic fibrosis with other manifestations
0.000 0.918 0.082
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.918 0.082
E24.0 Pituitary-dependent Cushing's disease
0.000 0.918 0.082
E80.6 Other disorders of bilirubin metabolism
0.000 0.919 0.081
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.919 0.081
E75.6 Lipid storage disorder, unspecified
0.000 0.920 0.080
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.920 0.080
E75.3 Sphingolipidosis, unspecified
0.000 0.920 0.080
E75.2 Other sphingolipidosis
0.000 0.920 0.080
E75.1 Other gangliosidosis
0.000 0.920 0.080
E75.0 GM2 gangliosidosis
0.000 0.920 0.080
E23.7 Disorder of pituitary gland, unspecified
0.000 0.921 0.079
E88.9 Metabolic disorder, unspecified
0.000 0.921 0.079
E34.5 Androgen resistance syndrome
0.000 0.921 0.079
E34.4 Constitutional tall stature
0.000 0.921 0.079
E34.3 Short stature, not elsewhere classified
0.000 0.921 0.079
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.921 0.079
E34.1 Other hypersecretion of intestinal hormones
0.000 0.921 0.079

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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