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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094123
log Bayes Factor = 34.9612
Chromosome 6   position 30,772,378  (GRCh37) Explore rs3094123 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.006 0.994
M06.9 Rheumatoid arthritis, unspecified
0.000 0.006 0.994
E14 Unspecified diabetes mellitus
0.000 0.008 0.992
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.008 0.992
E10.3 With ophthalmic complications
0.000 0.008 0.992
E14.9 Without complications
0.000 0.021 0.979
I25.1 Atherosclerotic heart disease
0.000 0.023 0.977
I25 Chronic ischaemic heart disease
0.000 0.023 0.977
I20-I25 Ischaemic heart diseases
0.000 0.026 0.974
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.033 0.967
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.036 0.964
I21 Acute myocardial infarction
0.000 0.040 0.960
E20-E35 Disorders of other endocrine glands
0.000 0.043 0.957
I22 Subsequent myocardial infarction
0.000 0.053 0.947
I24 Other acute ischaemic heart diseases
0.000 0.083 0.917
E10.1 With ketoacidosis
0.000 0.087 0.913
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.087 0.913
E00-E07 Disorders of thyroid gland
0.000 0.094 0.906
E23 Hypofunction and other disorders of pituitary gland
0.000 0.095 0.905
L40.0 Psoriasis vulgaris
0.000 0.097 0.903
E03 Other hypothyroidism
0.000 0.099 0.901
E03.9 Hypothyroidism, unspecified
0.000 0.101 0.899
E14.3 With ophthalmic complications
0.000 0.103 0.897
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.103 0.897
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.118 0.882
I21.9 Acute myocardial infarction, unspecified
0.000 0.127 0.873
E10.2 With renal complications
0.000 0.135 0.865
E11.5 With peripheral circulatory complications
0.000 0.140 0.860
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.143 0.857
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.144 0.856
E21.3 Hyperparathyroidism, unspecified
0.000 0.144 0.856
E11.0 With coma
0.000 0.148 0.852
E10.4 With neurological complications
0.000 0.157 0.843
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.158 0.842
I24.8 Other forms of acute ischaemic heart disease
0.000 0.161 0.839
E24 Cushing's syndrome
0.000 0.173 0.827
E11.2 With renal complications
0.000 0.186 0.814
I25.5 Ischaemic cardiomyopathy
0.000 0.189 0.811
E11.1 With ketoacidosis
0.000 0.189 0.811
E22 Hyperfunction of pituitary gland
0.000 0.190 0.810
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.194 0.806
E28 Ovarian dysfunction
0.000 0.199 0.801
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.211 0.789
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.215 0.785
E13 Other specified diabetes mellitus
0.000 0.215 0.785
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.217 0.783
L40.8 Other psoriasis
0.000 0.218 0.782
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.225 0.775
E29 Testicular dysfunction
0.000 0.227 0.773
E23.0 Hypopituitarism
0.000 0.227 0.773
E23.7 Disorder of pituitary gland, unspecified
0.000 0.244 0.756
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.259 0.741
I22.8 Subsequent myocardial infarction of other sites
0.000 0.266 0.734
E24.9 Cushing's syndrome, unspecified
0.000 0.266 0.734
E11.6 With other specified complications
0.000 0.267 0.732
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.269 0.731
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.271 0.729
E23.6 Other disorders of pituitary gland
0.000 0.272 0.728
E23.2 Diabetes insipidus
0.000 0.274 0.726
I23 Certain current complications following acute myocardial infarction
0.000 0.274 0.726
E03.8 Other specified hypothyroidism
0.000 0.277 0.723
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
I24.1 Dressler's syndrome
0.000 0.286 0.714
E22.0 Acromegaly and pituitary gigantism
0.000 0.287 0.713
E14.8 With unspecified complications
0.000 0.288 0.712
E14.7 With multiple complications
0.000 0.288 0.712
E14.6 With other specified complications
0.000 0.288 0.712
E14.1 With ketoacidosis
0.000 0.288 0.712
E14.0 With coma
0.000 0.288 0.712
E14.5 With peripheral circulatory complications
0.000 0.291 0.709
E07 Other disorders of thyroid
0.000 0.297 0.703
E28.2 Polycystic ovarian syndrome
0.000 0.300 0.700
I25.6 Silent myocardial ischaemia
0.000 0.300 0.700
E10.0 With coma
0.000 0.301 0.699
E10.8 With unspecified complications
0.000 0.301 0.699
I25.2 Old myocardial infarction
0.000 0.302 0.698
E10.6 With other specified complications
0.000 0.303 0.697
E10.5 With peripheral circulatory complications
0.000 0.304 0.696
E14.2 Withrenal complications
0.000 0.305 0.694
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.311 0.688
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.314 0.686
E32 Diseases of thymus
0.000 0.314 0.686
E31 Polyglandular dysfunction
0.000 0.314 0.686
E30 Disorders of puberty, not elsewhere classified
0.000 0.314 0.686
E25 Adrenogenital disorders
0.000 0.314 0.686
E14.4 With neurological complications
0.000 0.316 0.684
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.319 0.681
E50-E64 Other nutritional deficiencies
0.000 0.321 0.679
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.339 0.660
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.340 0.660
E78.0 Pure hypercholesterolaemia
0.000 0.341 0.659
E11.3 With ophthalmic complications
0.000 0.343 0.657
E40-E46 Malnutrition
0.000 0.345 0.655
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.346 0.654
E70-E90 Metabolic disorders
0.001 0.346 0.653
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.350 0.650
E00 Congenital iodine-deficiency syndrome
0.000 0.350 0.650
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.351 0.649
E23.1 Drug-induced hypopituitarism
0.000 0.351 0.649
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.352 0.648
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.353 0.647
E03.5 Myxoedema coma
0.000 0.354 0.646
E03.4 Atrophy of thyroid (acquired)
0.000 0.354 0.646
E03.3 Postinfectious hypothyroidism
0.000 0.354 0.646
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.354 0.646
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.357 0.643
E21.4 Other specified disorders of parathyroid gland
0.000 0.357 0.643
E21.2 Other hyperparathyroidism
0.000 0.357 0.643
E29.1 Testicular hypofunction
0.000 0.358 0.642
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.364 0.636
M06 Other rheumatoid arthritis
0.000 0.368 0.632
E13.9 Without complications
0.000 0.370 0.630
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.371 0.629
E20 Hypoparathyroidism
0.000 0.374 0.626
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.401 0.599
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.407 0.593
E24.8 Other Cushing's syndrome
0.000 0.407 0.593
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.407 0.593
E24.3 Ectopic ACTH syndrome
0.000 0.407 0.593
E24.2 Drug-induced Cushing's syndrome
0.000 0.407 0.593
E24.1 Nelson's syndrome
0.000 0.407 0.593
E24.0 Pituitary-dependent Cushing's disease
0.000 0.407 0.593
E07.8 Other specified disorders of thyroid
0.000 0.410 0.589
I25.4 Coronary artery aneurysm
0.000 0.411 0.589
E61 Deficiency of other nutrient elements
0.000 0.417 0.583
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.419 0.581
E22.8 Other hyperfunction of pituitary gland
0.000 0.419 0.581
E78.2 Mixed hyperlipidaemia
0.000 0.420 0.580
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.422 0.578
E78.1 Pure hyperglyceridaemia
0.000 0.423 0.577
E28.9 Ovarian dysfunction, unspecified
0.000 0.426 0.574
E28.8 Other ovarian dysfunction
0.000 0.426 0.574
E28.1 Androgen excess
0.000 0.426 0.574
E28.0 Oestrogen excess
0.000 0.426 0.574
E26 Hyperaldosteronism
0.000 0.435 0.565
E06 Thyroiditis
0.000 0.436 0.564
E13.8 With unspecified complications
0.000 0.437 0.562
E13.7 With multiple complications
0.000 0.437 0.562
E13.6 With other specified complications
0.000 0.437 0.562
E13.5 With peripheral circulatory complications
0.000 0.437 0.562
E13.4 With neurological complications
0.000 0.437 0.562
E13.3 With ophthalmic complications
0.000 0.437 0.562
E13.2 With renal complications
0.000 0.437 0.562
E13.1 With ketoacidosis
0.000 0.437 0.562
E13.0 With coma
0.000 0.437 0.562
I21.4 Acute subendocardial myocardial infarction
0.000 0.439 0.561
L40.3 Pustulosis palmaris et plantaris
0.000 0.445 0.554
E29.9 Testicular dysfunction, unspecified
0.000 0.445 0.554
E29.8 Other testicular dysfunction
0.000 0.445 0.554
E29.0 Testicular hyperfunction
0.000 0.445 0.554
E28.3 Primary ovarian failure
0.000 0.451 0.549
I23.8 Other current complications following acute myocardial infarction
0.000 0.452 0.548
E03.1 Congenital hypothyroidism without goitre
0.000 0.455 0.545
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.465 0.535
E61.1 Iron deficiency
0.000 0.469 0.531
I25.3 Aneurysm of heart
0.000 0.476 0.524
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.479 0.520
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.479 0.520
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.479 0.520
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.479 0.520
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.479 0.520
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.479 0.520
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.479 0.520
E11.4 With neurological complications
0.000 0.481 0.519
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M05-M14 Inflammatory polyarthropathies
0.000 0.494 0.506
E07.1 Dyshormogenetic goitre
0.000 0.496 0.504
E07.0 Hypersecretion of calcitonin
0.000 0.496 0.504
M07 Psoriatic and enteropathic arthropathies
0.000 0.497 0.503
M07.3 Other psoriatic arthropathies
0.000 0.498 0.502
E21.0 Primary hyperparathyroidism
0.000 0.501 0.499
E89.3 Postprocedural hypopituitarism
0.000 0.502 0.498
E11.8 With unspecified complications
0.001 0.505 0.495
E25.9 Adrenogenital disorder, unspecified
0.000 0.508 0.492
E25.8 Other adrenogenital disorders
0.000 0.508 0.492
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.508 0.492
E30.9 Disorder of puberty, unspecified
0.000 0.508 0.492
E30.8 Other disorders of puberty
0.000 0.508 0.492
E30.1 Precocious puberty
0.000 0.508 0.492
E30.0 Delayed puberty
0.000 0.508 0.492
E31.9 Polyglandular dysfunction, unspecified
0.000 0.508 0.492
E31.8 Other polyglandular dysfunction
0.000 0.508 0.492
E31.1 Polyglandular hyperfunction
0.000 0.508 0.492
E31.0 Autoimmune polyglandular failure
0.000 0.508 0.492
E32.9 Disease of thymus, unspecified
0.000 0.508 0.492
E32.8 Other diseases of thymus
0.000 0.508 0.492
E32.1 Abscess of thymus
0.000 0.508 0.492
E32.0 Persistent hyperplasia of thymus
0.000 0.508 0.492
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.508 0.492
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.508 0.492
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.508 0.492
E15 Nondiabetic hypoglycaemic coma
0.000 0.512 0.488
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.513 0.487
E63 Other nutritional deficiencies
0.000 0.513 0.487
E56 Other vitamin deficiencies
0.000 0.513 0.487
E51 Thiamine deficiency
0.000 0.513 0.487
E50 Vitamin A deficiency
0.000 0.513 0.487
E60 Dietary zinc deficiency
0.000 0.513 0.487
E59 Dietary selenium deficiency
0.000 0.513 0.487
E58 Dietary calcium deficiency
0.000 0.513 0.487
E54 Ascorbic acid deficiency
0.000 0.513 0.487
E52 Niacin deficiency [pellagra]
0.000 0.513 0.487
E22.1 Hyperprolactinaemia
0.000 0.518 0.482
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.519 0.481
E16 Other disorders of pancreatic internal secretion
0.000 0.524 0.476
E27 Other disorders of adrenal gland
0.000 0.529 0.471
M06.4 Inflammatory polyarthropathy
0.000 0.529 0.471
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.529 0.471
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.530 0.470
E45 Retarded development following protein-energy malnutrition
0.000 0.530 0.470
E43 Unspecified severe protein-energy malnutrition
0.000 0.530 0.470
E42 Marasmic kwashiorkor
0.000 0.530 0.470
E41 Nutritional marasmus
0.000 0.530 0.470
E40 Kwashiorkor
0.000 0.530 0.470
E78.6 Lipoprotein deficiency
0.000 0.531 0.469
E78.3 Hyperchylomicronaemia
0.000 0.531 0.469
E77 Disorders of glycoprotein metabolism
0.001 0.531 0.469
E76 Disorders of glycosaminoglycan metabolism
0.001 0.531 0.469
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.531 0.469
E72 Other disorders of amino-acid metabolism
0.001 0.531 0.469
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.531 0.469
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.531 0.469
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.534 0.466
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.534 0.466
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.534 0.466
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.534 0.466
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.534 0.466
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.534 0.466
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.534 0.466
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.534 0.466
E79 Disorders of purine and pyrimidine metabolism
0.001 0.540 0.459
E73 Lactose intolerance
0.001 0.541 0.459
E74 Other disorders of carbohydrate metabolism
0.001 0.542 0.457
M06.2 Rheumatoid bursitis
0.000 0.547 0.453
M06.1 Adult-onset Still's disease
0.000 0.547 0.453
E34 Other endocrine disorders
0.001 0.550 0.449
E20.8 Other hypoparathyroidism
0.000 0.551 0.449
E20.1 Pseudohypoparathyroidism
0.000 0.551 0.449
E20.0 Idiopathic hypoparathyroidism
0.000 0.551 0.449
E07.9 Disorder of thyroid, unspecified
0.000 0.552 0.448
E84 Cystic fibrosis
0.001 0.553 0.446
E70 Disorders of aromatic amino-acid metabolism
0.001 0.561 0.438
E53 Deficiency of other B group vitamins
0.000 0.561 0.439
M06.3 Rheumatoid nodule
0.000 0.562 0.438
E46 Unspecified protein-energy malnutrition
0.000 0.568 0.432
E78.4 Other hyperlipidaemia
0.000 0.572 0.428
M05 Seropositive rheumatoid arthritis
0.000 0.572 0.428
M06.8 Other specified rheumatoid arthritis
0.000 0.576 0.423
E27.9 Disorder of adrenal gland, unspecified
0.000 0.577 0.423
E83 Disorders of mineral metabolism
0.188 0.581 0.231
E61.9 Deficiency of nutrient element, unspecified
0.000 0.582 0.418
E61.8 Deficiency of other specified nutrient elements
0.000 0.582 0.418
E61.7 Deficiency of multiple nutrient elements
0.000 0.582 0.418
E61.6 Vanadium deficiency
0.000 0.582 0.418
E61.5 Molybdenum deficiency
0.000 0.582 0.418
E61.4 Chromium deficiency
0.000 0.582 0.418
E61.3 Manganese deficiency
0.000 0.582 0.418
E61.0 Copper deficiency
0.000 0.582 0.418
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.589 0.410
E89.2 Postprocedural hypoparathyroidism
0.000 0.592 0.408
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.593 0.407
E26.9 Hyperaldosteronism, unspecified
0.000 0.594 0.405
E26.8 Other hyperaldosteronism
0.000 0.594 0.405
E26.1 Secondary hyperaldosteronism
0.000 0.594 0.405
E06.5 Other chronic thyroiditis
0.000 0.595 0.405
E06.4 Drug-induced thyroiditis
0.000 0.595 0.405
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.595 0.405
E06.1 Subacute thyroiditis
0.000 0.595 0.405
E06.0 Acute thyroiditis
0.000 0.595 0.405
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.606 0.394
E20.9 Hypoparathyroidism, unspecified
0.000 0.611 0.388
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.612 0.388
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.616 0.383
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.616 0.383
E89.5 Postprocedural testicular hypofunction
0.000 0.616 0.383
E89.1 Postprocedural hypoinsulinaemia
0.000 0.616 0.383
E16.1 Other hypoglycaemia
0.000 0.617 0.383
E78.8 Other disorders of lipoprotein metabolism
0.000 0.622 0.377
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.628 0.372
E06.3 Autoimmune thyroiditis
0.000 0.629 0.371
E65-E68 Obesity and other hyperalimentation
0.000 0.630 0.370
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.632 0.368
E61.2 Magnesium deficiency
0.000 0.634 0.366
E89.4 Postprocedural ovarian failure
0.000 0.634 0.365
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.637 0.363
M08 Juvenile arthritis
0.000 0.637 0.363
E06.9 Thyroiditis, unspecified
0.000 0.638 0.361
M07.6 Other enteropathic arthropathies
0.000 0.639 0.360
M07.5 Arthropathy in ulcerative colitis
0.000 0.639 0.360
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.639 0.360
M07.2 Psoriatic spondylitis
0.000 0.639 0.360
M07.1 Arthritis mutilans
0.000 0.639 0.360
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.639 0.360
M07.38 Other psoriatic arthropathies (Other)
0.000 0.640 0.360
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.640 0.360
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.640 0.360
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.640 0.360
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.640 0.360
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.640 0.360
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.640 0.360
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.641 0.358
E55 Vitamin D deficiency
0.000 0.649 0.350
E50.9 Vitamin A deficiency, unspecified
0.000 0.651 0.349
E50.8 Other manifestations of vitamin A deficiency
0.000 0.651 0.349
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.651 0.349
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.651 0.349
E50.5 Vitamin A deficiency with night blindness
0.000 0.651 0.349
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.651 0.349
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.651 0.349
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.651 0.349
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.651 0.349
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.651 0.349
E51.9 Thiamine deficiency, unspecified
0.000 0.651 0.349
E51.8 Other manifestations of thiamine deficiency
0.000 0.651 0.349
E51.2 Wernicke's encephalopathy
0.000 0.651 0.349
E51.1 Beriberi
0.000 0.651 0.349
E56.9 Vitamin deficiency, unspecified
0.000 0.651 0.349
E56.8 Deficiency of other vitamins
0.000 0.651 0.349
E56.1 Deficiency of vitamin K
0.000 0.651 0.349
E56.0 Deficiency of vitamin E
0.000 0.651 0.349
E63.9 Nutritional deficiency, unspecified
0.000 0.651 0.349
E63.8 Other specified nutritional deficiencies
0.000 0.651 0.349
E63.1 Imbalance of constituents of food intake
0.000 0.651 0.349
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.651 0.349
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.651 0.349
E64.8 Sequelae of other nutritional deficiencies
0.000 0.651 0.349
E64.3 Sequelae of rickets
0.000 0.651 0.349
E64.2 Sequelae of vitamin C deficiency
0.000 0.651 0.349
E64.1 Sequelae of vitamin A deficiency
0.000 0.651 0.349
E64.0 Sequelae of protein-energy malnutrition
0.000 0.651 0.349
E85 Amyloidosis
0.001 0.651 0.348
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.658 0.341
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.658 0.341
E16.4 Abnormal secretion of gastrin
0.000 0.658 0.341
E16.3 Increased secretion of glucagon
0.000 0.658 0.341
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.662 0.338
E27.5 Adrenomedullary hyperfunction
0.000 0.662 0.338
E27.0 Other adrenocortical overactivity
0.000 0.662 0.338
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.662 0.337
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.662 0.337
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.662 0.337
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.662 0.337
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.662 0.337
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.662 0.337
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.662 0.337
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.662 0.337
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.663 0.337
E44.1 Mild protein-energy malnutrition
0.000 0.663 0.337
E44.0 Moderate protein-energy malnutrition
0.000 0.663 0.337
E71.3 Disorders of fatty-acid metabolism
0.001 0.663 0.336
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.663 0.336
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.663 0.336
E71.0 Maple-syrup-urine disease
0.001 0.663 0.336
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.663 0.336
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.663 0.336
E72.5 Disorders of glycine metabolism
0.001 0.663 0.336
E72.4 Disorders of ornithine metabolism
0.001 0.663 0.336
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.663 0.336
E72.2 Disorders of urea cycle metabolism
0.001 0.663 0.336
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.663 0.336
E72.0 Disorders of amino-acid transport
0.001 0.663 0.336
E75.6 Lipid storage disorder, unspecified
0.001 0.663 0.336
E75.5 Other lipid storage disorders
0.001 0.663 0.336
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.663 0.336
E75.3 Sphingolipidosis, unspecified
0.001 0.663 0.336
E75.2 Other sphingolipidosis
0.001 0.663 0.336
E75.1 Other gangliosidosis
0.001 0.663 0.336
E75.0 GM2 gangliosidosis
0.001 0.663 0.336
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.663 0.336
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.663 0.336
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.663 0.336
E76.2 Other mucopolysaccharidoses
0.001 0.663 0.336
E76.1 Mucopolysaccharidosis, type II
0.001 0.663 0.336
E76.0 Mucopolysaccharidosis, type I
0.001 0.663 0.336
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.663 0.336
E77.8 Other disorders of glycoprotein metabolism
0.001 0.663 0.336
E77.1 Defects in glycoprotein degradation
0.001 0.663 0.336
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.663 0.336
E88 Other metabolic disorders
0.001 0.665 0.334
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.667 0.333
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.670 0.329
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.670 0.329
E79.1 Lesch-Nyhan syndrome
0.001 0.670 0.329
E73.8 Other lactose intolerance
0.001 0.671 0.329
E73.1 Secondary lactase deficiency
0.001 0.671 0.329
E73.0 Congenital lactase deficiency
0.001 0.671 0.329
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.672 0.328
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.672 0.328
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.672 0.328
E74.2 Disorders of galactose metabolism
0.001 0.672 0.328
E74.1 Disorders of fructose metabolism
0.001 0.672 0.328
E74.0 Glycogen storage disease
0.001 0.672 0.328
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.672 0.328
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.675 0.325
M06.18 Adult-onset Still's disease (Other)
0.000 0.675 0.325
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.675 0.325
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.675 0.325
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.675 0.325
M06.14 Adult-onset Still's disease (Hand)
0.000 0.675 0.325
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.675 0.325
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.675 0.325
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.675 0.325
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.675 0.325
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.675 0.325
M06.28 Rheumatoid bursitis (Other)
0.000 0.675 0.325
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.675 0.325
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.675 0.325
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.675 0.325
M06.24 Rheumatoid bursitis (Hand)
0.000 0.675 0.325
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.675 0.325
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.675 0.325
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.675 0.325
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.675 0.325
E34.5 Androgen resistance syndrome
0.001 0.677 0.322
E34.4 Constitutional tall stature
0.001 0.677 0.322
E34.3 Short stature, not elsewhere classified
0.001 0.677 0.322
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.677 0.322
E34.1 Other hypersecretion of intestinal hormones
0.001 0.677 0.322
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.679 0.321
E84.8 Cystic fibrosis with other manifestations
0.001 0.679 0.320
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.679 0.320
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.679 0.320
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.679 0.320
E73.9 Lactose intolerance, unspecified
0.000 0.681 0.319
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.681 0.319
G35 Multiple sclerosis
0.317 0.683 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.683 0.316
M12 Other specific arthropathies
0.000 0.684 0.316
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.685 0.314
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.685 0.314
E70.2 Disorders of tyrosine metabolism
0.001 0.685 0.314
E70.1 Other hyperphenylalaninaemias
0.001 0.685 0.314
E70.0 Classical phenylketonuria
0.001 0.685 0.314
E53.1 Pyridoxine deficiency
0.000 0.685 0.315
E53.0 Riboflavin deficiency
0.000 0.685 0.315
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.686 0.314
M06.38 Rheumatoid nodule (Other)
0.000 0.686 0.314
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.686 0.314
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.686 0.314
M06.33 Rheumatoid nodule (Forearm)
0.000 0.686 0.314
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.686 0.314
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.687 0.313
M14 Arthropathies in other diseases classified elsewhere
0.000 0.687 0.312
M06.0 Seronegative rheumatoid arthritis
0.000 0.690 0.310
M05.8 Other seropositive rheumatoid arthritis
0.000 0.693 0.307
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.693 0.307
M05.2 Rheumatoid vasculitis
0.000 0.693 0.307
M05.1 Rheumatoid lung disease
0.000 0.693 0.307
M05.0 Felty's syndrome
0.000 0.693 0.307
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.696 0.304
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.696 0.304
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.696 0.304
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.696 0.304
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.696 0.304
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.696 0.304
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.696 0.304
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.696 0.304
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.696 0.304
M11 Other crystal arthropathies
0.000 0.697 0.303
E83.9 Disorder of mineral metabolism, unspecified
0.135 0.699 0.166
E83.8 Other disorders of mineral metabolism
0.135 0.699 0.166
E83.2 Disorders of zinc metabolism
0.135 0.699 0.166
E83.0 Disorders of copper metabolism
0.135 0.699 0.166
E34.8 Other specified endocrine disorders
0.001 0.700 0.299
E84.9 Cystic fibrosis, unspecified
0.001 0.701 0.298
E34.9 Endocrine disorder, unspecified
0.001 0.706 0.294
E53.8 Deficiency of other specified B group vitamins
0.000 0.707 0.293
E53.9 Vitamin B deficiency, unspecified
0.000 0.708 0.292
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.708 0.292
M13 Other arthritis
0.000 0.710 0.290
E70.3 Albinism
0.001 0.715 0.284
E26.0 Primary hyperaldosteronism
0.001 0.715 0.284
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.716 0.284
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.726 0.274
M06.34 Rheumatoid nodule (Hand)
0.000 0.731 0.269
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.733 0.266
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.733 0.266

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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