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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094188
log Bayes Factor = 95.2558
Chromosome 6   position 31,142,245  (GRCh37) Explore rs3094188 on Ensembl!
Variant rs3094188 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E11.9 Without complications
0.000 0.008 0.992
E11 Non-insulin-dependent diabetes mellitus
0.000 0.011 0.989
M45 Ankylosing spondylitis
0.979 0.021 0.000
E10.1 With ketoacidosis
0.000 0.023 0.977
E10.3 With ophthalmic complications
0.000 0.029 0.971
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.963 0.037 0.000
E14 Unspecified diabetes mellitus
0.000 0.045 0.955
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.047 0.953
E16 Other disorders of pancreatic internal secretion
0.000 0.079 0.921
E14.3 With ophthalmic complications
0.000 0.100 0.900
E16.2 Hypoglycaemia, unspecified
0.000 0.118 0.882
E10.5 With peripheral circulatory complications
0.000 0.132 0.868
E11.0 With coma
0.000 0.159 0.841
E03.8 Other specified hypothyroidism
0.000 0.170 0.830
E11.1 With ketoacidosis
0.000 0.186 0.814
M45.X2 Ankylosing spondylitis (Cervical region)
0.812 0.188 0.000
E10.6 With other specified complications
0.000 0.197 0.803
M45.X6 Ankylosing spondylitis (Lumbar region)
0.799 0.201 0.000
K90 Intestinal malabsorption
0.000 0.203 0.797
E14.1 With ketoacidosis
0.000 0.222 0.778
L40 Psoriasis
0.000 0.229 0.771
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.233 0.767
E16.1 Other hypoglycaemia
0.000 0.239 0.761
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.245 0.755
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.746 0.254 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.261 0.739
E10.2 With renal complications
0.000 0.262 0.738
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.267 0.733
E14.2 Withrenal complications
0.000 0.276 0.724
E40-E46 Malnutrition
0.000 0.277 0.723
E10.0 With coma
0.000 0.279 0.721
E10.8 With unspecified complications
0.000 0.280 0.720
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E14.9 Without complications
0.000 0.287 0.713
E11.7 With multiple complications
0.000 0.291 0.709
E14.5 With peripheral circulatory complications
0.000 0.293 0.707
E03.1 Congenital hypothyroidism without goitre
0.000 0.297 0.703
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.702 0.298 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.702 0.298 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.702 0.298 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.702 0.298 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.702 0.298 0.000
L40.0 Psoriasis vulgaris
0.000 0.301 0.699
E14.6 With other specified complications
0.000 0.304 0.696
E10.7 With multiple complications
0.000 0.308 0.692
E14.7 With multiple complications
0.000 0.315 0.685
E14.0 With coma
0.000 0.315 0.685
E15 Nondiabetic hypoglycaemic coma
0.000 0.316 0.683
K51.9 Ulcerative colitis, unspecified
0.682 0.318 0.000
E14.8 With unspecified complications
0.000 0.333 0.667
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.334 0.666
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.340 0.660
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.340 0.660
E16.4 Abnormal secretion of gastrin
0.000 0.340 0.660
E16.3 Increased secretion of glucagon
0.000 0.340 0.660
E05.8 Other thyrotoxicosis
0.000 0.372 0.628
E14.4 With neurological complications
0.000 0.381 0.618
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.386 0.613
K90.9 Intestinal malabsorption, unspecified
0.000 0.413 0.587
E07 Other disorders of thyroid
0.000 0.415 0.585
L40.5 Arthropathic psoriasis
0.000 0.424 0.576
K90.3 Pancreatic steatorrhoea
0.000 0.428 0.572
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.428 0.572
K90.1 Tropical sprue
0.000 0.428 0.572
E13 Other specified diabetes mellitus
0.000 0.431 0.569
L40.8 Other psoriasis
0.000 0.446 0.554
L40.2 Acrodermatitis continua
0.000 0.447 0.553
K51 Ulcerative colitis
0.551 0.449 0.000
L40.4 Guttate psoriasis
0.000 0.452 0.548
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.453 0.547
E78.0 Pure hypercholesterolaemia
0.000 0.456 0.544
E70-E90 Metabolic disorders
0.001 0.456 0.542
K90.8 Other intestinal malabsorption
0.000 0.458 0.542
E10.4 With neurological complications
0.000 0.458 0.542
E46 Unspecified protein-energy malnutrition
0.000 0.474 0.526
L40.1 Generalised pustular psoriasis
0.000 0.476 0.524
E11.8 With unspecified complications
0.000 0.476 0.524
E78.2 Mixed hyperlipidaemia
0.000 0.478 0.522
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.481 0.519
E45 Retarded development following protein-energy malnutrition
0.000 0.481 0.519
E43 Unspecified severe protein-energy malnutrition
0.000 0.481 0.519
E42 Marasmic kwashiorkor
0.000 0.481 0.519
E41 Nutritional marasmus
0.000 0.481 0.519
E40 Kwashiorkor
0.000 0.481 0.519
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
K51.4 Pseudopolyposis of colon
0.509 0.491 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.496 0.504
E78.8 Other disorders of lipoprotein metabolism
0.000 0.508 0.492
K51.5 Mucosal proctocolitis
0.483 0.517 0.000
E78.4 Other hyperlipidaemia
0.000 0.538 0.462
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.545 0.455
E06 Thyroiditis
0.000 0.547 0.452
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.549 0.451
L40-L45 Papulosquamous disorders
0.000 0.549 0.450
K51.2 Ulcerative (chronic) proctitis
0.440 0.560 0.000
E83 Disorders of mineral metabolism
0.414 0.560 0.026
L40.3 Pustulosis palmaris et plantaris
0.000 0.560 0.439
E79 Disorders of purine and pyrimidine metabolism
0.001 0.560 0.439
E28 Ovarian dysfunction
0.000 0.565 0.434
E24 Cushing's syndrome
0.000 0.566 0.434
E74 Other disorders of carbohydrate metabolism
0.001 0.574 0.425
E07.1 Dyshormogenetic goitre
0.000 0.580 0.420
E07.0 Hypersecretion of calcitonin
0.000 0.580 0.420
E21.3 Hyperparathyroidism, unspecified
0.000 0.586 0.413
E11.6 With other specified complications
0.001 0.587 0.413
E11.2 With renal complications
0.000 0.587 0.413
E13.8 With unspecified complications
0.000 0.592 0.408
E13.7 With multiple complications
0.000 0.592 0.408
E13.6 With other specified complications
0.000 0.592 0.408
E13.5 With peripheral circulatory complications
0.000 0.592 0.408
E13.4 With neurological complications
0.000 0.592 0.408
E13.2 With renal complications
0.000 0.592 0.408
E13.1 With ketoacidosis
0.000 0.592 0.408
E13.0 With coma
0.000 0.592 0.408
E78.6 Lipoprotein deficiency
0.000 0.592 0.408
E28.2 Polycystic ovarian syndrome
0.000 0.593 0.407
E07.9 Disorder of thyroid, unspecified
0.000 0.601 0.399
K51.3 Ulcerative (chronic) rectosigmoiditis
0.397 0.603 0.000
E78.3 Hyperchylomicronaemia
0.000 0.607 0.392
K51.8 Other ulcerative colitis
0.392 0.608 0.000
E77 Disorders of glycoprotein metabolism
0.001 0.610 0.389
E76 Disorders of glycosaminoglycan metabolism
0.001 0.610 0.389
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.610 0.389
E70 Disorders of aromatic amino-acid metabolism
0.001 0.610 0.389
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.610 0.389
E25 Adrenogenital disorders
0.000 0.619 0.381
E72 Other disorders of amino-acid metabolism
0.001 0.622 0.377
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.623 0.376
L43 Lichen planus
0.000 0.627 0.373
E24.0 Pituitary-dependent Cushing's disease
0.000 0.627 0.373
E44.1 Mild protein-energy malnutrition
0.000 0.628 0.372
E44.0 Moderate protein-energy malnutrition
0.000 0.628 0.372
E83.3 Disorders of phosphorus metabolism
0.361 0.633 0.006
E88 Other metabolic disorders
0.001 0.634 0.365
E73 Lactose intolerance
0.001 0.634 0.365
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.635 0.364
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.638 0.362
E32 Diseases of thymus
0.000 0.638 0.362
E31 Polyglandular dysfunction
0.000 0.638 0.362
E30 Disorders of puberty, not elsewhere classified
0.000 0.638 0.362
E11.5 With peripheral circulatory complications
0.000 0.642 0.358
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.643 0.356
E13.3 With ophthalmic complications
0.000 0.645 0.354
E26 Hyperaldosteronism
0.000 0.646 0.354
K51.1 Ulcerative (chronic) ileocolitis
0.351 0.649 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.650 0.350
E24.2 Drug-induced Cushing's syndrome
0.000 0.653 0.347
E06.5 Other chronic thyroiditis
0.000 0.656 0.344
L43.9 Lichen planus, unspecified
0.000 0.656 0.344
L42 Pityriasis rosea
0.000 0.657 0.343
E13.9 Without complications
0.000 0.662 0.337
E11.3 With ophthalmic complications
0.000 0.663 0.337
E83.9 Disorder of mineral metabolism, unspecified
0.314 0.669 0.017
E24.9 Cushing's syndrome, unspecified
0.000 0.671 0.328
E06.4 Drug-induced thyroiditis
0.000 0.675 0.324
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.675 0.324
E06.0 Acute thyroiditis
0.000 0.675 0.324
E21.4 Other specified disorders of parathyroid gland
0.000 0.677 0.323
L44 Other papulosquamous disorders
0.000 0.677 0.323
L41 Parapsoriasis
0.000 0.677 0.323
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.677 0.323
E07.8 Other specified disorders of thyroid
0.000 0.679 0.321
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.681 0.319
E06.1 Subacute thyroiditis
0.000 0.682 0.318
E83.8 Other disorders of mineral metabolism
0.297 0.684 0.019
E83.2 Disorders of zinc metabolism
0.297 0.684 0.019
E83.0 Disorders of copper metabolism
0.297 0.684 0.019
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.685 0.315
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.685 0.315
E79.1 Lesch-Nyhan syndrome
0.001 0.685 0.315
E84 Cystic fibrosis
0.002 0.687 0.311
E28.9 Ovarian dysfunction, unspecified
0.000 0.688 0.312
E28.8 Other ovarian dysfunction
0.000 0.688 0.312
E28.1 Androgen excess
0.000 0.688 0.312
E28.0 Oestrogen excess
0.000 0.688 0.312
E21.0 Primary hyperparathyroidism
0.000 0.688 0.312
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.689 0.311
E24.3 Ectopic ACTH syndrome
0.000 0.689 0.311
E24.1 Nelson's syndrome
0.000 0.689 0.311
E21.2 Other hyperparathyroidism
0.000 0.692 0.308
E23 Hypofunction and other disorders of pituitary gland
0.000 0.692 0.308
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.693 0.307
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.695 0.305
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.695 0.305
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.695 0.305
E74.2 Disorders of galactose metabolism
0.001 0.695 0.305
E74.1 Disorders of fructose metabolism
0.001 0.695 0.305
C18.7 Sigmoid colon
0.000 0.699 0.301
E20 Hypoparathyroidism
0.000 0.704 0.295
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.705 0.294
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.707 0.293
E74.0 Glycogen storage disease
0.001 0.709 0.291
K51.0 Ulcerative (chronic) enterocolitis
0.288 0.712 0.000
E88.8 Other specified metabolic disorders
0.000 0.714 0.286
E88.9 Metabolic disorder, unspecified
0.000 0.716 0.284
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.720 0.279
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.720 0.279
E70.3 Albinism
0.001 0.720 0.279
E70.2 Disorders of tyrosine metabolism
0.001 0.720 0.279
E70.1 Other hyperphenylalaninaemias
0.001 0.720 0.279
E70.0 Classical phenylketonuria
0.001 0.720 0.279
E71.3 Disorders of fatty-acid metabolism
0.001 0.720 0.279
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.720 0.279
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.720 0.279
E71.0 Maple-syrup-urine disease
0.001 0.720 0.279
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.720 0.279
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.720 0.279
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.720 0.279
E76.2 Other mucopolysaccharidoses
0.001 0.720 0.279
E76.1 Mucopolysaccharidosis, type II
0.001 0.720 0.279
E76.0 Mucopolysaccharidosis, type I
0.001 0.720 0.279
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.720 0.279
E77.8 Other disorders of glycoprotein metabolism
0.001 0.720 0.279
E77.1 Defects in glycoprotein degradation
0.001 0.720 0.279
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.720 0.279
E25.9 Adrenogenital disorder, unspecified
0.000 0.727 0.273
E25.8 Other adrenogenital disorders
0.000 0.727 0.273
E88.2 Lipomatosis, not elsewhere classified
0.000 0.728 0.271
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.729 0.270
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.729 0.270
E72.5 Disorders of glycine metabolism
0.001 0.729 0.270
E72.4 Disorders of ornithine metabolism
0.001 0.729 0.270
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.729 0.270
E72.2 Disorders of urea cycle metabolism
0.001 0.729 0.270
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.729 0.270
E24.8 Other Cushing's syndrome
0.000 0.729 0.271
E75.6 Lipid storage disorder, unspecified
0.001 0.730 0.269
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.730 0.269
E75.3 Sphingolipidosis, unspecified
0.001 0.730 0.269
E75.2 Other sphingolipidosis
0.001 0.730 0.269
E75.1 Other gangliosidosis
0.001 0.730 0.269
E75.0 GM2 gangliosidosis
0.001 0.730 0.269
E88.3 Tumour lysis syndrome
0.000 0.732 0.268
L43.3 Subacute (active) lichen planus
0.000 0.732 0.268
L43.2 Lichenoid drug reaction
0.000 0.732 0.268
L43.1 Bullous lichen planus
0.000 0.732 0.268
L43.0 Hypertrophic lichen planus
0.000 0.732 0.268
E26.0 Primary hyperaldosteronism
0.000 0.734 0.266
E73.8 Other lactose intolerance
0.001 0.738 0.261
E73.1 Secondary lactase deficiency
0.001 0.738 0.261
E73.0 Congenital lactase deficiency
0.001 0.738 0.261
E78.5 Hyperlipidaemia, unspecified
0.000 0.739 0.261
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.740 0.260
E22 Hyperfunction of pituitary gland
0.000 0.740 0.260
E30.9 Disorder of puberty, unspecified
0.000 0.740 0.259
E30.8 Other disorders of puberty
0.000 0.740 0.259
E30.1 Precocious puberty
0.000 0.740 0.259
E30.0 Delayed puberty
0.000 0.740 0.259
E31.9 Polyglandular dysfunction, unspecified
0.000 0.740 0.259
E31.8 Other polyglandular dysfunction
0.000 0.740 0.259
E31.1 Polyglandular hyperfunction
0.000 0.740 0.259
E31.0 Autoimmune polyglandular failure
0.000 0.740 0.259
E32.9 Disease of thymus, unspecified
0.000 0.740 0.259
E32.8 Other diseases of thymus
0.000 0.740 0.259
E32.1 Abscess of thymus
0.000 0.740 0.259
E32.0 Persistent hyperplasia of thymus
0.000 0.740 0.259
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.740 0.259
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.740 0.259
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.740 0.259
E72.0 Disorders of amino-acid transport
0.001 0.741 0.258
E75.5 Other lipid storage disorders
0.001 0.743 0.256
E26.8 Other hyperaldosteronism
0.000 0.746 0.254
E26.1 Secondary hyperaldosteronism
0.000 0.746 0.254
E29 Testicular dysfunction
0.000 0.749 0.250
E23.7 Disorder of pituitary gland, unspecified
0.000 0.751 0.249
E65-E68 Obesity and other hyperalimentation
0.001 0.753 0.246
M45-M49 Spondylopathies
0.244 0.756 0.000
E73.9 Lactose intolerance, unspecified
0.001 0.762 0.237
E89.4 Postprocedural ovarian failure
0.000 0.763 0.236
E89.3 Postprocedural hypopituitarism
0.000 0.767 0.233
L41.9 Parapsoriasis, unspecified
0.000 0.768 0.232
L41.8 Other parapsoriasis
0.000 0.768 0.232
L41.5 Retiform parapsoriasis
0.000 0.768 0.232
L41.4 Large plaque parapsoriasis
0.000 0.768 0.232
L41.3 Small plaque parapsoriasis
0.000 0.768 0.232
L41.2 Lymphomatoid papulosis
0.000 0.768 0.232
L41.1 Pityriasis lichenoides chronica
0.000 0.768 0.232
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.768 0.232
L44.9 Papulosquamous disorder, unspecified
0.000 0.768 0.232
L44.8 Other specified papulosquamous disorders
0.000 0.768 0.232
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.768 0.232
L44.3 Lichen ruber moniliformis
0.000 0.768 0.232
L44.2 Lichen striatus
0.000 0.768 0.232
L44.1 Lichen nitidus
0.000 0.768 0.232
L44.0 Pityriasis rubra pilaris
0.000 0.768 0.232
E26.9 Hyperaldosteronism, unspecified
0.000 0.768 0.231
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.769 0.230
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.771 0.229
E89.5 Postprocedural testicular hypofunction
0.000 0.771 0.229
E89.1 Postprocedural hypoinsulinaemia
0.000 0.771 0.229
E84.8 Cystic fibrosis with other manifestations
0.001 0.776 0.223
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.776 0.223
E78.1 Pure hyperglyceridaemia
0.001 0.776 0.223
E80.6 Other disorders of bilirubin metabolism
0.001 0.777 0.222
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.778 0.222
E06.3 Autoimmune thyroiditis
0.000 0.779 0.221
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.779 0.221
E23.1 Drug-induced hypopituitarism
0.000 0.779 0.221
E80.2 Other porphyria
0.001 0.782 0.217
E34 Other endocrine disorders
0.001 0.785 0.215
E23.2 Diabetes insipidus
0.000 0.785 0.215
E28.3 Primary ovarian failure
0.000 0.786 0.214
E80.1 Porphyria cutanea tarda
0.001 0.787 0.212
E20.8 Other hypoparathyroidism
0.000 0.788 0.212
E20.1 Pseudohypoparathyroidism
0.000 0.788 0.212
E20.0 Idiopathic hypoparathyroidism
0.000 0.788 0.212
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.788 0.211
E80.5 Crigler-Najjar syndrome
0.001 0.788 0.211
E80.3 Defects of catalase and peroxydase
0.001 0.788 0.211
E80.0 Hereditary erythropoietic porphyria
0.001 0.788 0.211
E89.2 Postprocedural hypoparathyroidism
0.000 0.789 0.211
E06.9 Thyroiditis, unspecified
0.001 0.792 0.207
E23.6 Other disorders of pituitary gland
0.000 0.793 0.207
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.798 0.202
M48 Other spondylopathies
0.200 0.800 0.000
E50-E64 Other nutritional deficiencies
0.000 0.801 0.199
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.808 0.191
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.808 0.192
E84.9 Cystic fibrosis, unspecified
0.001 0.809 0.190
E83.4 Disorders of magnesium metabolism
0.178 0.812 0.010
M48.5 Collapsed vertebra, not elsewhere classified
0.188 0.812 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.814 0.186
E22.8 Other hyperfunction of pituitary gland
0.000 0.814 0.186
E29.9 Testicular dysfunction, unspecified
0.000 0.820 0.180
E29.8 Other testicular dysfunction
0.000 0.820 0.180
E29.0 Testicular hyperfunction
0.000 0.820 0.180
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.822 0.178
L43.8 Other lichen planus
0.000 0.822 0.177
E67 Other hyperalimentation
0.001 0.823 0.176
E68 Sequelae of hyperalimentation
0.001 0.823 0.176
E85 Amyloidosis
0.002 0.832 0.166
E22.1 Hyperprolactinaemia
0.000 0.834 0.166
M46 Other inflammatory spondylopathies
0.166 0.834 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.163 0.837 0.000
E27 Other disorders of adrenal gland
0.000 0.840 0.159
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.155 0.844 0.000
E34.5 Androgen resistance syndrome
0.001 0.845 0.154
E34.4 Constitutional tall stature
0.001 0.845 0.154
E34.3 Short stature, not elsewhere classified
0.001 0.845 0.154
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.845 0.154
E34.1 Other hypersecretion of intestinal hormones
0.001 0.845 0.154
M49 Spondylopathies in diseases classified elsewhere
0.149 0.851 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.147 0.853 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.146 0.854 0.000
E20.9 Hypoparathyroidism, unspecified
0.001 0.854 0.145
M48.8 Other specified spondylopathies
0.145 0.855 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.856 0.144
M48.4 Fatigue fracture of vertebra
0.144 0.856 0.000
M48.3 Traumatic spondylopathy
0.144 0.856 0.000
M48.2 Kissing spine
0.144 0.856 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.144 0.856 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.857 0.143
E63 Other nutritional deficiencies
0.000 0.857 0.143
E50 Vitamin A deficiency
0.000 0.857 0.143
E60 Dietary zinc deficiency
0.000 0.857 0.143
E59 Dietary selenium deficiency
0.000 0.857 0.143
E52 Niacin deficiency [pellagra]
0.000 0.857 0.143
E23.0 Hypopituitarism
0.000 0.860 0.140
E61 Deficiency of other nutrient elements
0.000 0.862 0.138
M48.9 Spondylopathy, unspecified
0.138 0.862 0.000
E34.8 Other specified endocrine disorders
0.001 0.863 0.137
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.135 0.865 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.135 0.865 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.135 0.865 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.135 0.865 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.135 0.865 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.134 0.865 0.000
E56 Other vitamin deficiencies
0.000 0.867 0.133
E51 Thiamine deficiency
0.000 0.867 0.133
E27.9 Disorder of adrenal gland, unspecified
0.000 0.869 0.131
E58 Dietary calcium deficiency
0.000 0.870 0.130
E67.8 Other specified hyperalimentation
0.001 0.873 0.126
E67.3 Hypervitaminosis D
0.001 0.873 0.126
E67.2 Megavitamin-B6 syndrome
0.001 0.873 0.126
E67.1 Hypercarotenaemia
0.001 0.873 0.126
E67.0 Hypervitaminosis A
0.001 0.873 0.126
E04 Other non-toxic goitre
0.000 0.873 0.127
M46.2 Osteomyelitis of vertebra
0.126 0.874 0.000
E54 Ascorbic acid deficiency
0.000 0.875 0.124
E83.5 Disorders of calcium metabolism
0.120 0.877 0.003
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.879 0.121
E85.2 Heredofamilial amyloidosis, unspecified
0.002 0.879 0.119
E85.1 Neuropathic heredofamilial amyloidosis
0.002 0.879 0.119
E85.0 Nonneuropathic heredofamilial amyloidosis
0.002 0.879 0.119
M46.3 Infection of intervertebral disk (pyogenic)
0.120 0.880 0.000
K91.4 Colostomy and enterostomy malfunction
0.120 0.880 0.000
M46.4 Discitis, unspecified
0.120 0.880 0.000
M46.8 Other specified inflammatory spondylopathies
0.119 0.881 0.000
M46.5 Other infective spondylopathies
0.119 0.881 0.000
E85.8 Other amyloidosis
0.002 0.882 0.117
M46.0 Spinal enthesopathy
0.117 0.883 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.885 0.114
E27.0 Other adrenocortical overactivity
0.000 0.885 0.114
M46.1 Sacro-iliitis, not elsewhere classified
0.113 0.886 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.889 0.110
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)
0.109 0.891 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.107 0.893 0.000
M49.4 Neuropathic spondylopathy
0.107 0.893 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.107 0.893 0.000
M49.2 Enterobacterial spondylitis
0.107 0.893 0.000
M49.1 Brucella spondylitis
0.107 0.893 0.000
M49.0 Tuberculosis of spine
0.107 0.893 0.000
E11.4 With neurological complications
0.001 0.893 0.106
M46.9 Inflammatory spondylopathy, unspecified
0.106 0.894 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.895 0.105
E27.1 Primary adrenocortical insufficiency
0.000 0.896 0.104
M48.89 Other specified spondylopathies (Site unspecified)
0.104 0.896 0.000
M48.87 Other specified spondylopathies (Lumbosacral region)
0.104 0.896 0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)
0.104 0.896 0.000
M48.84 Other specified spondylopathies (Thoracic region)
0.104 0.896 0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)
0.104 0.896 0.000
M48.82 Other specified spondylopathies (Cervical region)
0.104 0.896 0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)
0.104 0.896 0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)
0.104 0.896 0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.103 0.897 0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.103 0.897 0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.103 0.897 0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)
0.103 0.897 0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)
0.103 0.897 0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)
0.103 0.897 0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)
0.103 0.897 0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)
0.103 0.897 0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)
0.103 0.897 0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)
0.103 0.897 0.000
M48.29 Kissing spine (Site unspecified)
0.103 0.897 0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)
0.103 0.897 0.000
M48.27 Kissing spine (Lumbosacral region)
0.103 0.897 0.000
M48.26 Kissing spine (Lumbar region)
0.103 0.897 0.000
M48.25 Kissing spine (Thoracolumbar region)
0.103 0.897 0.000
M48.24 Kissing spine (Thoracic region)
0.103 0.897 0.000
M48.23 Kissing spine (Cervicothoracic region)
0.103 0.897 0.000
M48.22 Kissing spine (Cervical region)
0.103 0.897 0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)
0.103 0.897 0.000
M48.20 Kissing spine (Multiple sites in spine)
0.103 0.897 0.000
M48.39 Traumatic spondylopathy (Site unspecified)
0.103 0.897 0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)
0.103 0.897 0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)
0.103 0.897 0.000
M48.36 Traumatic spondylopathy (Lumbar region)
0.103 0.897 0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)
0.103 0.897 0.000
M48.34 Traumatic spondylopathy (Thoracic region)
0.103 0.897 0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)
0.103 0.897 0.000
M48.32 Traumatic spondylopathy (Cervical region)
0.103 0.897 0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)
0.103 0.897 0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)
0.103 0.897 0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)
0.103 0.897 0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)
0.103 0.897 0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)
0.103 0.897 0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)
0.103 0.897 0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)
0.103 0.897 0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)
0.103 0.897 0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)
0.103 0.897 0.000
M48.42 Fatigue fracture of vertebra (Cervical region)
0.103 0.897 0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)
0.103 0.897 0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)
0.103 0.897 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.897 0.103
E50.8 Other manifestations of vitamin A deficiency
0.000 0.897 0.103
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.897 0.103
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.897 0.103
E50.5 Vitamin A deficiency with night blindness
0.000 0.897 0.103
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.897 0.103
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.897 0.103

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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