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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094215
log Bayes Factor = 97.6112
Chromosome 6   position 31,084,684  (GRCh37) Explore rs3094215 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
M45 Ankylosing spondylitis
0.995 0.005 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.993 0.007 0.000
L40.0 Psoriasis vulgaris
0.984 0.016 0.000
G35 Multiple sclerosis
0.000 0.022 0.978
E06 Thyroiditis
0.000 0.040 0.960
L40.8 Other psoriasis
0.935 0.065 0.000
E06.3 Autoimmune thyroiditis
0.000 0.066 0.934
L40.4 Guttate psoriasis
0.876 0.124 0.000
L40.1 Generalised pustular psoriasis
0.841 0.159 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.818 0.182 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.210 0.790
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.212 0.788
E10-E14 Diabetes mellitus
0.000 0.233 0.767
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.234 0.766
E10.1 With ketoacidosis
0.000 0.235 0.765
E10.3 With ophthalmic complications
0.000 0.238 0.762
M45.X6 Ankylosing spondylitis (Lumbar region)
0.754 0.246 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.745 0.255 0.000
E10.2 With renal complications
0.000 0.256 0.744
E10.4 With neurological complications
0.000 0.278 0.722
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.714 0.286 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.714 0.286 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.714 0.286 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.714 0.286 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.714 0.286 0.000
E05.8 Other thyrotoxicosis
0.000 0.294 0.706
E06.9 Thyroiditis, unspecified
0.000 0.296 0.704
E03.1 Congenital hypothyroidism without goitre
0.000 0.297 0.703
E06.5 Other chronic thyroiditis
0.000 0.302 0.698
E06.4 Drug-induced thyroiditis
0.000 0.312 0.688
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.312 0.688
E06.0 Acute thyroiditis
0.000 0.312 0.688
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.323 0.676
L40.3 Pustulosis palmaris et plantaris
0.676 0.323 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.342 0.657
E40-E46 Malnutrition
0.000 0.360 0.640
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.369 0.631
E03.8 Other specified hypothyroidism
0.000 0.371 0.628
E06.1 Subacute thyroiditis
0.000 0.376 0.624
E07 Other disorders of thyroid
0.000 0.377 0.623
M35.0 Sicca syndrome [Sjogren]
0.000 0.395 0.605
E10.5 With peripheral circulatory complications
0.000 0.407 0.593
E14 Unspecified diabetes mellitus
0.000 0.409 0.591
E10.7 With multiple complications
0.000 0.446 0.554
E10.0 With coma
0.000 0.448 0.552
E12 Malnutrition-related diabetes mellitus
0.000 0.450 0.550
E46 Unspecified protein-energy malnutrition
0.000 0.451 0.549
E10.8 With unspecified complications
0.000 0.457 0.542
E14.3 With ophthalmic complications
0.000 0.467 0.533
E10.9 Without complications
0.000 0.467 0.533
E10.6 With other specified complications
0.000 0.478 0.522
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E14.8 With unspecified complications
0.000 0.523 0.477
E07.8 Other specified disorders of thyroid
0.000 0.524 0.475
E14.2 Withrenal complications
0.000 0.529 0.471
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.530 0.470
E04 Other non-toxic goitre
0.000 0.532 0.468
E27.1 Primary adrenocortical insufficiency
0.000 0.537 0.463
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.541 0.459
E45 Retarded development following protein-energy malnutrition
0.000 0.541 0.459
E43 Unspecified severe protein-energy malnutrition
0.000 0.541 0.459
E42 Marasmic kwashiorkor
0.000 0.541 0.459
E41 Nutritional marasmus
0.000 0.541 0.459
E40 Kwashiorkor
0.000 0.541 0.459
E14.6 With other specified complications
0.000 0.549 0.451
E07.1 Dyshormogenetic goitre
0.000 0.553 0.447
E07.0 Hypersecretion of calcitonin
0.000 0.553 0.447
E14.1 With ketoacidosis
0.000 0.554 0.446
E20-E35 Disorders of other endocrine glands
0.000 0.556 0.444
E27 Other disorders of adrenal gland
0.000 0.557 0.443
E14.5 With peripheral circulatory complications
0.000 0.560 0.440
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.562 0.438
R31 Unspecified haematuria
0.435 0.565 0.000
E14.7 With multiple complications
0.000 0.576 0.424
E14.0 With coma
0.000 0.576 0.424
E04.0 Non-toxic diffuse goitre
0.000 0.579 0.421
E13 Other specified diabetes mellitus
0.000 0.580 0.420
K90 Intestinal malabsorption
0.000 0.600 0.400
E27.2 Addisonian crisis
0.000 0.602 0.398
E12.9 Without complications
0.000 0.605 0.394
E12.8 With unspecified complications
0.000 0.605 0.394
E12.7 With multiple complications
0.000 0.605 0.394
E12.6 With other specified complications
0.000 0.605 0.394
E12.5 With peripheral circulatory complications
0.000 0.605 0.394
E12.4 With neurological complications
0.000 0.605 0.394
E12.3 With ophthalmic complications
0.000 0.605 0.394
E12.2 With renal complications
0.000 0.605 0.394
E12.1 With ketoacidosis
0.000 0.605 0.394
E12.0 With coma
0.000 0.605 0.394
L40-L45 Papulosquamous disorders
0.386 0.614 0.000
E50-E64 Other nutritional deficiencies
0.000 0.632 0.368
G36 Other acute disseminated demyelination
0.000 0.638 0.361
E20 Hypoparathyroidism
0.000 0.648 0.352
G37 Other demyelinating diseases of central nervous system
0.000 0.657 0.343
M45-M49 Spondylopathies
0.341 0.659 0.000
E04.8 Other specified non-toxic goitre
0.000 0.664 0.336
E44.1 Mild protein-energy malnutrition
0.000 0.671 0.329
E44.0 Moderate protein-energy malnutrition
0.000 0.671 0.329
E13.3 With ophthalmic complications
0.000 0.678 0.321
L41 Parapsoriasis
0.319 0.681 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.681 0.319
E32 Diseases of thymus
0.000 0.681 0.319
E31 Polyglandular dysfunction
0.000 0.681 0.319
E30 Disorders of puberty, not elsewhere classified
0.000 0.681 0.319
E27.5 Adrenomedullary hyperfunction
0.000 0.682 0.317
E27.0 Other adrenocortical overactivity
0.000 0.682 0.317
E15 Nondiabetic hypoglycaemic coma
0.000 0.686 0.314
E28 Ovarian dysfunction
0.000 0.687 0.313
E65-E68 Obesity and other hyperalimentation
0.000 0.692 0.308
K90.8 Other intestinal malabsorption
0.000 0.693 0.306
E13.8 With unspecified complications
0.000 0.698 0.301
E13.7 With multiple complications
0.000 0.698 0.301
E13.6 With other specified complications
0.000 0.698 0.301
E13.5 With peripheral circulatory complications
0.000 0.698 0.301
E13.4 With neurological complications
0.000 0.698 0.301
E13.2 With renal complications
0.000 0.698 0.301
E13.1 With ketoacidosis
0.000 0.698 0.301
E13.0 With coma
0.000 0.698 0.301
E07.9 Disorder of thyroid, unspecified
0.000 0.699 0.301
M07.3 Other psoriatic arthropathies
0.300 0.700 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.293 0.707 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.291 0.709 0.000
L42 Pityriasis rosea
0.289 0.711 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.713 0.287
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.713 0.287
K90.1 Tropical sprue
0.000 0.713 0.287
E53 Deficiency of other B group vitamins
0.000 0.713 0.287
E20.9 Hypoparathyroidism, unspecified
0.000 0.714 0.286
G36.0 Neuromyelitis optica [Devic]
0.000 0.716 0.284
L44 Other papulosquamous disorders
0.280 0.720 0.000
E51 Thiamine deficiency
0.000 0.720 0.280
L45 Papulosquamous disorders in diseases classified elsewhere
0.277 0.723 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.273 0.726 0.000
E54 Ascorbic acid deficiency
0.000 0.727 0.273
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.727 0.273
L41.1 Pityriasis lichenoides chronica
0.271 0.729 0.000
M49 Spondylopathies in diseases classified elsewhere
0.266 0.734 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.734 0.266
E25 Adrenogenital disorders
0.001 0.734 0.265
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.736 0.264
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.736 0.264
E63 Other nutritional deficiencies
0.000 0.736 0.264
E50 Vitamin A deficiency
0.000 0.736 0.264
E60 Dietary zinc deficiency
0.000 0.736 0.264
E59 Dietary selenium deficiency
0.000 0.736 0.264
E52 Niacin deficiency [pellagra]
0.000 0.736 0.264
M47 Spondylosis
0.263 0.737 0.000
E28.3 Primary ovarian failure
0.000 0.740 0.260
E26 Hyperaldosteronism
0.000 0.741 0.259
G36.9 Acute disseminated demyelination, unspecified
0.000 0.741 0.259
G36.8 Other specified acute disseminated demyelination
0.000 0.741 0.259
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.741 0.259
E14.4 With neurological complications
0.001 0.742 0.258
K90.9 Intestinal malabsorption, unspecified
0.000 0.746 0.254
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.746 0.253
E20.8 Other hypoparathyroidism
0.000 0.747 0.252
E20.1 Pseudohypoparathyroidism
0.000 0.747 0.252
E20.0 Idiopathic hypoparathyroidism
0.000 0.747 0.252
M07.34 Other psoriatic arthropathies (Hand)
0.252 0.748 0.000
M47.8 Other spondylosis
0.250 0.750 0.000
E34 Other endocrine disorders
0.000 0.750 0.249
M07.38 Other psoriatic arthropathies (Other)
0.249 0.751 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.754 0.246
G37.4 Subacute necrotising myelitis
0.000 0.754 0.246
G37.2 Central pontine myelinolysis
0.000 0.754 0.246
G37.1 Central demyelination of corpus callosum
0.000 0.754 0.246
G37.0 Diffuse sclerosis
0.000 0.754 0.246
E56 Other vitamin deficiencies
0.000 0.756 0.244
E24 Cushing's syndrome
0.000 0.757 0.242
M07.31 Other psoriatic arthropathies (Shoulder region)
0.236 0.764 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.766 0.234
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.769 0.231
M47.80 Other spondylosis (Multiple sites in spine)
0.230 0.770 0.000
L41.9 Parapsoriasis, unspecified
0.229 0.771 0.000
L41.8 Other parapsoriasis
0.229 0.771 0.000
L41.5 Retiform parapsoriasis
0.229 0.771 0.000
L41.4 Large plaque parapsoriasis
0.229 0.771 0.000
L41.3 Small plaque parapsoriasis
0.229 0.771 0.000
L41.2 Lymphomatoid papulosis
0.229 0.771 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.229 0.771 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.771 0.228
E30.8 Other disorders of puberty
0.000 0.771 0.228
E30.1 Precocious puberty
0.000 0.771 0.228
E30.0 Delayed puberty
0.000 0.771 0.228
E31.9 Polyglandular dysfunction, unspecified
0.000 0.771 0.228
E31.8 Other polyglandular dysfunction
0.000 0.771 0.228
E31.1 Polyglandular hyperfunction
0.000 0.771 0.228
E31.0 Autoimmune polyglandular failure
0.000 0.771 0.228
E32.9 Disease of thymus, unspecified
0.000 0.771 0.228
E32.8 Other diseases of thymus
0.000 0.771 0.228
E32.1 Abscess of thymus
0.000 0.771 0.228
E32.0 Persistent hyperplasia of thymus
0.000 0.771 0.228
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.771 0.228
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.771 0.228
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.771 0.228
M47.87 Other spondylosis (Lumbosacral region)
0.225 0.775 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.775 0.225
E28.8 Other ovarian dysfunction
0.000 0.775 0.225
E28.1 Androgen excess
0.000 0.775 0.225
E28.0 Oestrogen excess
0.000 0.775 0.225
E53.9 Vitamin B deficiency, unspecified
0.000 0.775 0.225
E04.9 Non-toxic goitre, unspecified
0.000 0.776 0.224
E58 Dietary calcium deficiency
0.000 0.778 0.222
M47.89 Other spondylosis (Site unspecified)
0.221 0.779 0.000
E67 Other hyperalimentation
0.000 0.779 0.221
E68 Sequelae of hyperalimentation
0.000 0.779 0.221
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.218 0.782 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.217 0.783 0.000
E51.2 Wernicke's encephalopathy
0.000 0.783 0.217
M07.33 Other psoriatic arthropathies (Forearm)
0.215 0.785 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.215 0.785 0.000
M35 Other systemic involvement of connective tissue
0.000 0.785 0.215
E27.8 Other specified disorders of adrenal gland
0.000 0.785 0.214
M49.5 Collapsed vertebra in diseases classified elsewhere
0.213 0.787 0.000
E21.0 Primary hyperparathyroidism
0.000 0.789 0.211
E53.8 Deficiency of other specified B group vitamins
0.000 0.790 0.210
E23 Hypofunction and other disorders of pituitary gland
0.001 0.792 0.207
E61 Deficiency of other nutrient elements
0.000 0.792 0.207
E53.1 Pyridoxine deficiency
0.000 0.794 0.206
E53.0 Riboflavin deficiency
0.000 0.794 0.206
L44.0 Pityriasis rubra pilaris
0.204 0.796 0.000
E29 Testicular dysfunction
0.002 0.797 0.201
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.797 0.203
E16 Other disorders of pancreatic internal secretion
0.000 0.798 0.202
L44.9 Papulosquamous disorder, unspecified
0.201 0.799 0.000
L44.8 Other specified papulosquamous disorders
0.201 0.799 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.201 0.799 0.000
L44.3 Lichen ruber moniliformis
0.201 0.799 0.000
L44.2 Lichen striatus
0.201 0.799 0.000
L44.1 Lichen nitidus
0.201 0.799 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.799 0.201
E51.8 Other manifestations of thiamine deficiency
0.000 0.799 0.201
E51.1 Beriberi
0.000 0.799 0.201
E65 Localised adiposity
0.000 0.801 0.199
M47.84 Other spondylosis (Thoracic region)
0.192 0.808 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.191 0.809 0.000
M49.4 Neuropathic spondylopathy
0.191 0.809 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.191 0.809 0.000
M49.2 Enterobacterial spondylitis
0.191 0.809 0.000
M49.1 Brucella spondylitis
0.191 0.809 0.000
M49.0 Tuberculosis of spine
0.191 0.809 0.000
E25.9 Adrenogenital disorder, unspecified
0.001 0.809 0.190
E25.8 Other adrenogenital disorders
0.001 0.809 0.190
M47.2 Other spondylosis with radiculopathy
0.190 0.810 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.810 0.189
E50.8 Other manifestations of vitamin A deficiency
0.000 0.810 0.189
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.810 0.189
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.810 0.189
E50.5 Vitamin A deficiency with night blindness
0.000 0.810 0.189
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.810 0.189
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.810 0.189
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.810 0.189
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.810 0.189
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.810 0.189
E63.9 Nutritional deficiency, unspecified
0.000 0.810 0.189
E63.8 Other specified nutritional deficiencies
0.000 0.810 0.189
E63.1 Imbalance of constituents of food intake
0.000 0.810 0.189
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.810 0.189
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.810 0.189
E64.8 Sequelae of other nutritional deficiencies
0.000 0.810 0.189
E64.3 Sequelae of rickets
0.000 0.810 0.189
E64.2 Sequelae of vitamin C deficiency
0.000 0.810 0.189
E64.1 Sequelae of vitamin A deficiency
0.000 0.810 0.189
E64.0 Sequelae of protein-energy malnutrition
0.000 0.810 0.189
M47.83 Other spondylosis (Cervicothoracic region)
0.189 0.811 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.189 0.811 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.188 0.812 0.000
E27.9 Disorder of adrenal gland, unspecified
0.001 0.813 0.186
E26.8 Other hyperaldosteronism
0.000 0.814 0.186
E26.1 Secondary hyperaldosteronism
0.000 0.814 0.186
M46 Other inflammatory spondylopathies
0.186 0.814 0.000
E55 Vitamin D deficiency
0.000 0.814 0.186
M07 Psoriatic and enteropathic arthropathies
0.185 0.815 0.000
M35.7 Hypermobility syndrome
0.000 0.815 0.185
E26.9 Hyperaldosteronism, unspecified
0.000 0.815 0.184
M47.85 Other spondylosis (Thoracolumbar region)
0.183 0.817 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.818 0.181
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.820 0.179
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.180 0.820 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.820 0.179
E23.2 Diabetes insipidus
0.000 0.821 0.179
E34.5 Androgen resistance syndrome
0.000 0.821 0.179
E34.4 Constitutional tall stature
0.000 0.821 0.179
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.821 0.179
E34.1 Other hypersecretion of intestinal hormones
0.000 0.821 0.179
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.178 0.821 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.822 0.178
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.824 0.176
E56.9 Vitamin deficiency, unspecified
0.000 0.824 0.175
E56.8 Deficiency of other vitamins
0.000 0.824 0.175
E56.0 Deficiency of vitamin E
0.000 0.824 0.175
E24.8 Other Cushing's syndrome
0.000 0.825 0.174
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.826 0.174
E24.3 Ectopic ACTH syndrome
0.000 0.826 0.174
E24.1 Nelson's syndrome
0.000 0.826 0.174
E21.4 Other specified disorders of parathyroid gland
0.000 0.826 0.173
M47.1 Other spondylosis with myelopathy
0.169 0.831 0.000
M46.4 Discitis, unspecified
0.168 0.832 0.000
M35.1 Other overlap syndromes
0.000 0.833 0.167
E34.8 Other specified endocrine disorders
0.000 0.836 0.164
E21.2 Other hyperparathyroidism
0.000 0.837 0.163
E61.2 Magnesium deficiency
0.000 0.840 0.160
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.841 0.159
E67.8 Other specified hyperalimentation
0.000 0.841 0.158
E67.3 Hypervitaminosis D
0.000 0.841 0.158
E67.2 Megavitamin-B6 syndrome
0.000 0.841 0.158
E67.1 Hypercarotenaemia
0.000 0.841 0.158
E67.0 Hypervitaminosis A
0.000 0.841 0.158
E28.2 Polycystic ovarian syndrome
0.000 0.842 0.158
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)
0.158 0.842 0.000
M48 Other spondylopathies
0.157 0.843 0.000
E56.1 Deficiency of vitamin K
0.000 0.844 0.155
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.155 0.845 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.846 0.154
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.846 0.154
M35.5 Multifocal fibrosclerosis
0.000 0.846 0.154
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.846 0.154
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.847 0.153
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)
0.153 0.847 0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)
0.153 0.847 0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)
0.153 0.847 0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)
0.153 0.847 0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)
0.153 0.847 0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)
0.153 0.847 0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)
0.153 0.847 0.000
E22 Hyperfunction of pituitary gland
0.000 0.847 0.152
E24.9 Cushing's syndrome, unspecified
0.000 0.849 0.151
L43 Lichen planus
0.150 0.850 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.851 0.148
E23.1 Drug-induced hypopituitarism
0.001 0.851 0.148
E61.9 Deficiency of nutrient element, unspecified
0.000 0.851 0.149
E61.8 Deficiency of other specified nutrient elements
0.000 0.851 0.149
E61.7 Deficiency of multiple nutrient elements
0.000 0.851 0.149
E61.6 Vanadium deficiency
0.000 0.851 0.149
E61.5 Molybdenum deficiency
0.000 0.851 0.149
E61.4 Chromium deficiency
0.000 0.851 0.149
E61.3 Manganese deficiency
0.000 0.851 0.149
E61.0 Copper deficiency
0.000 0.851 0.149
M35.8 Other specified systemic involvement of connective tissue
0.000 0.854 0.146
E29.9 Testicular dysfunction, unspecified
0.002 0.854 0.144
E29.8 Other testicular dysfunction
0.002 0.854 0.144
E29.0 Testicular hyperfunction
0.002 0.854 0.144
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.855 0.145
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.855 0.145
E16.4 Abnormal secretion of gastrin
0.000 0.855 0.145
E16.3 Increased secretion of glucagon
0.000 0.855 0.145
M46.46 Discitis, unspecified (Lumbar region)
0.142 0.857 0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.141 0.858 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.861 0.138
E04.1 Non-toxic single thyroid nodule
0.000 0.862 0.138
E23.6 Other disorders of pituitary gland
0.001 0.862 0.137
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.862 0.137
M49.09 Tuberculosis of spine (Site unspecified)
0.137 0.863 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.137 0.863 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.137 0.863 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.137 0.863 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.137 0.863 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.137 0.863 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.137 0.863 0.000
M49.02 Tuberculosis of spine (Cervical region)
0.137 0.863 0.000
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.137 0.863 0.000
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.137 0.863 0.000
M49.19 Brucella spondylitis (Site unspecified)
0.137 0.863 0.000
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)
0.137 0.863 0.000
M49.17 Brucella spondylitis (Lumbosacral region)
0.137 0.863 0.000
M49.16 Brucella spondylitis (Lumbar region)
0.137 0.863 0.000
M49.15 Brucella spondylitis (Thoracolumbar region)
0.137 0.863 0.000
M49.14 Brucella spondylitis (Thoracic region)
0.137 0.863 0.000
M49.13 Brucella spondylitis (Cervicothoracic region)
0.137 0.863 0.000
M49.12 Brucella spondylitis (Cervical region)
0.137 0.863 0.000
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)
0.137 0.863 0.000
M49.10 Brucella spondylitis (Multiple sites in spine)
0.137 0.863 0.000
M49.29 Enterobacterial spondylitis (Site unspecified)
0.137 0.863 0.000
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)
0.137 0.863 0.000
M49.27 Enterobacterial spondylitis (Lumbosacral region)
0.137 0.863 0.000
M49.26 Enterobacterial spondylitis (Lumbar region)
0.137 0.863 0.000
M49.25 Enterobacterial spondylitis (Thoracolumbar region)
0.137 0.863 0.000
M49.24 Enterobacterial spondylitis (Thoracic region)
0.137 0.863 0.000
M49.23 Enterobacterial spondylitis (Cervicothoracic region)
0.137 0.863 0.000
M49.22 Enterobacterial spondylitis (Cervical region)
0.137 0.863 0.000
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)
0.137 0.863 0.000
M49.20 Enterobacterial spondylitis (Multiple sites in spine)
0.137 0.863 0.000
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)
0.137 0.863 0.000
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)
0.137 0.863 0.000
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)
0.137 0.863 0.000
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)
0.137 0.863 0.000
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)
0.137 0.863 0.000
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)
0.137 0.863 0.000
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)
0.137 0.863 0.000
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)
0.137 0.863 0.000
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)
0.137 0.863 0.000
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)
0.137 0.863 0.000
M49.49 Neuropathic spondylopathy (Site unspecified)
0.137 0.863 0.000
M49.48 Neuropathic spondylopathy (Sacral and sacrococcygeal region)
0.137 0.863 0.000
M49.47 Neuropathic spondylopathy (Lumbosacral region)
0.137 0.863 0.000
M49.46 Neuropathic spondylopathy (Lumbar region)
0.137 0.863 0.000
M49.45 Neuropathic spondylopathy (Thoracolumbar region)
0.137 0.863 0.000
M49.44 Neuropathic spondylopathy (Thoracic region)
0.137 0.863 0.000
M49.43 Neuropathic spondylopathy (Cervicothoracic region)
0.137 0.863 0.000
M49.42 Neuropathic spondylopathy (Cervical region)
0.137 0.863 0.000
M49.41 Neuropathic spondylopathy (Occipito-atlanto-axial region)
0.137 0.863 0.000
M49.40 Neuropathic spondylopathy (Multiple sites in spine)
0.137 0.863 0.000
M49.89 Spondylopathy in other diseases classified elsewhere (Site unspecified)
0.137 0.863 0.000
M49.88 Spondylopathy in other diseases classified elsewhere (Sacral and sacrococcygeal region)
0.137 0.863 0.000
M49.87 Spondylopathy in other diseases classified elsewhere (Lumbosacral region)
0.137 0.863 0.000
M49.86 Spondylopathy in other diseases classified elsewhere (Lumbar region)
0.137 0.863 0.000
M49.85 Spondylopathy in other diseases classified elsewhere (Thoracolumbar region)
0.137 0.863 0.000
M49.84 Spondylopathy in other diseases classified elsewhere (Thoracic region)
0.137 0.863 0.000
M49.83 Spondylopathy in other diseases classified elsewhere (Cervicothoracic region)
0.137 0.863 0.000
M49.82 Spondylopathy in other diseases classified elsewhere (Cervical region)
0.137 0.863 0.000
M49.81 Spondylopathy in other diseases classified elsewhere (Occipito-atlanto-axial region)
0.137 0.863 0.000
M49.80 Spondylopathy in other diseases classified elsewhere (Multiple sites in spine)
0.137 0.863 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.137 0.863 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.136 0.863 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.136 0.863 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.136 0.863 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.136 0.863 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.136 0.863 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.136 0.863 0.000
M47.82 Other spondylosis (Cervical region)
0.136 0.864 0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)
0.135 0.864 0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)
0.135 0.864 0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)
0.135 0.864 0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)
0.135 0.864 0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)
0.135 0.864 0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)
0.135 0.864 0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)
0.135 0.864 0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)
0.135 0.864 0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)
0.135 0.864 0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)
0.135 0.864 0.000
E34.0 Carcinoid syndrome
0.001 0.866 0.134
M46.8 Other specified inflammatory spondylopathies
0.133 0.866 0.000
M46.5 Other infective spondylopathies
0.133 0.866 0.000
E55.0 Rickets, active
0.000 0.867 0.133
M07.5 Arthropathy in ulcerative colitis
0.133 0.867 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.133 0.867 0.000
M07.2 Psoriatic spondylitis
0.133 0.867 0.000
M07.1 Arthritis mutilans
0.133 0.867 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.133 0.867 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.133 0.867 0.000
M46.42 Discitis, unspecified (Cervical region)
0.131 0.868 0.000
M46.0 Spinal enthesopathy
0.131 0.869 0.000
M07.6 Other enteropathic arthropathies
0.131 0.869 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.131 0.869 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.130 0.870 0.000
E26.0 Primary hyperaldosteronism
0.001 0.870 0.129
M35.2 Behcet's disease
0.000 0.873 0.127
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.125 0.875 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.123 0.877 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.122 0.878 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.122 0.878 0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.121 0.879 0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.121 0.879 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.121 0.879 0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.121 0.879 0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.121 0.879 0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.121 0.879 0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.121 0.879 0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.121 0.879 0.000
E13.9 Without complications
0.001 0.879 0.121
M48.9 Spondylopathy, unspecified
0.121 0.879 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.121 0.879 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.121 0.879 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.121 0.879 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.121 0.879 0.000
E24.0 Pituitary-dependent Cushing's disease
0.001 0.880 0.119
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.119 0.880 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.118 0.882 0.000
E23.7 Disorder of pituitary gland, unspecified
0.001 0.887 0.112
M48.4 Fatigue fracture of vertebra
0.113 0.887 0.000
M48.3 Traumatic spondylopathy
0.113 0.887 0.000
M48.2 Kissing spine
0.113 0.887 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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