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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094226
log Bayes Factor = 54.5349
Chromosome 6   position 31,112,899  (GRCh37) Explore rs3094226 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
G35 Multiple sclerosis
0.995 0.005 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.005 0.995
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.009 0.991
E70-E90 Metabolic disorders
0.000 0.014 0.986
L40 Psoriasis
0.000 0.084 0.916
E14 Unspecified diabetes mellitus
0.000 0.084 0.916
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.091 0.909
M06.9 Rheumatoid arthritis, unspecified
0.000 0.093 0.907
E11.0 With coma
0.000 0.129 0.871
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.135 0.865
E78.8 Other disorders of lipoprotein metabolism
0.000 0.140 0.860
L40.5 Arthropathic psoriasis
0.000 0.154 0.846
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.160 0.840
E07 Other disorders of thyroid
0.000 0.172 0.828
E10.3 With ophthalmic complications
0.000 0.179 0.821
E78.2 Mixed hyperlipidaemia
0.000 0.181 0.819
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.181 0.819
E14.3 With ophthalmic complications
0.000 0.189 0.811
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.194 0.806
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.195 0.805
E11.1 With ketoacidosis
0.000 0.216 0.784
E74 Other disorders of carbohydrate metabolism
0.000 0.221 0.779
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.231 0.769
E79 Disorders of purine and pyrimidine metabolism
0.000 0.232 0.768
L40.0 Psoriasis vulgaris
0.000 0.233 0.767
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.235 0.765
E03.8 Other specified hypothyroidism
0.000 0.235 0.765
E78.1 Pure hyperglyceridaemia
0.000 0.236 0.764
L40.8 Other psoriasis
0.000 0.239 0.761
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.240 0.759
G35-G37 Demyelinating diseases of the central nervous system
0.757 0.243 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.245 0.755
E78.4 Other hyperlipidaemia
0.000 0.250 0.750
E10.6 With other specified complications
0.000 0.254 0.746
E10.8 With unspecified complications
0.000 0.258 0.741
E13 Other specified diabetes mellitus
0.000 0.272 0.728
E11.2 With renal complications
0.000 0.272 0.728
E14.9 Without complications
0.000 0.274 0.726
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.275 0.725
E14.5 With peripheral circulatory complications
0.000 0.281 0.719
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.285 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.714
E07.9 Disorder of thyroid, unspecified
0.000 0.288 0.712
E40-E46 Malnutrition
0.000 0.289 0.711
E78.3 Hyperchylomicronaemia
0.000 0.289 0.711
E78.5 Hyperlipidaemia, unspecified
0.000 0.291 0.709
E77 Disorders of glycoprotein metabolism
0.000 0.293 0.707
E76 Disorders of glycosaminoglycan metabolism
0.000 0.293 0.707
E72 Other disorders of amino-acid metabolism
0.000 0.293 0.707
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.293 0.707
E70 Disorders of aromatic amino-acid metabolism
0.000 0.293 0.707
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.293 0.707
E78.6 Lipoprotein deficiency
0.000 0.294 0.706
E10.0 With coma
0.000 0.299 0.701
L40.1 Generalised pustular psoriasis
0.000 0.304 0.696
G37 Other demyelinating diseases of central nervous system
0.693 0.307 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.312 0.688
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.315 0.685
E10.1 With ketoacidosis
0.000 0.316 0.684
E14.1 With ketoacidosis
0.000 0.319 0.681
E84 Cystic fibrosis
0.000 0.322 0.678
E14.4 With neurological complications
0.000 0.323 0.677
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.336 0.664
L40.2 Acrodermatitis continua
0.000 0.343 0.657
E14.7 With multiple complications
0.000 0.343 0.657
E14.0 With coma
0.000 0.343 0.657
E14.6 With other specified complications
0.000 0.343 0.657
L40.4 Guttate psoriasis
0.000 0.351 0.648
E14.2 Withrenal complications
0.000 0.354 0.646
K90 Intestinal malabsorption
0.000 0.368 0.632
G37.9 Demyelinating disease of central nervous system, unspecified
0.632 0.368 0.000
E80.6 Other disorders of bilirubin metabolism
0.000 0.370 0.630
E03.1 Congenital hypothyroidism without goitre
0.000 0.370 0.630
E05.8 Other thyrotoxicosis
0.000 0.384 0.616
E80.4 Gilbert's syndrome
0.000 0.385 0.615
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.387 0.613
E14.8 With unspecified complications
0.000 0.388 0.612
E11.8 With unspecified complications
0.000 0.388 0.612
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.388 0.612
E80.2 Other porphyria
0.000 0.388 0.612
E83 Disorders of mineral metabolism
0.553 0.393 0.054
E16 Other disorders of pancreatic internal secretion
0.000 0.403 0.597
E10.2 With renal complications
0.000 0.403 0.597
E07.1 Dyshormogenetic goitre
0.000 0.406 0.594
E07.0 Hypersecretion of calcitonin
0.000 0.406 0.594
G36 Other acute disseminated demyelination
0.583 0.416 0.000
E07.8 Other specified disorders of thyroid
0.000 0.421 0.579
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.422 0.578
E80.5 Crigler-Najjar syndrome
0.000 0.422 0.578
E80.3 Defects of catalase and peroxydase
0.000 0.422 0.578
E80.0 Hereditary erythropoietic porphyria
0.000 0.422 0.578
E80.1 Porphyria cutanea tarda
0.000 0.430 0.570
E10.5 With peripheral circulatory complications
0.000 0.433 0.567
G37.8 Other specified demyelinating diseases of central nervous system
0.562 0.438 0.000
E73 Lactose intolerance
0.000 0.438 0.562
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.441 0.559
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.441 0.559
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.441 0.559
E74.2 Disorders of galactose metabolism
0.000 0.441 0.559
E74.1 Disorders of fructose metabolism
0.000 0.441 0.559
E13.9 Without complications
0.000 0.442 0.558
E11.5 With peripheral circulatory complications
0.000 0.447 0.553
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.449 0.551
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.449 0.551
E79.1 Lesch-Nyhan syndrome
0.000 0.449 0.551
E15 Nondiabetic hypoglycaemic coma
0.000 0.451 0.549
E88 Other metabolic disorders
0.000 0.455 0.545
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.457 0.543
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.461 0.539
L40.3 Pustulosis palmaris et plantaris
0.000 0.464 0.535
E13.8 With unspecified complications
0.000 0.478 0.522
E13.7 With multiple complications
0.000 0.478 0.522
E13.6 With other specified complications
0.000 0.478 0.522
E13.5 With peripheral circulatory complications
0.000 0.478 0.522
E13.4 With neurological complications
0.000 0.478 0.522
E13.2 With renal complications
0.000 0.478 0.522
E13.1 With ketoacidosis
0.000 0.478 0.522
E13.0 With coma
0.000 0.478 0.522
E85 Amyloidosis
0.000 0.481 0.519
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.490 0.510
E45 Retarded development following protein-energy malnutrition
0.000 0.490 0.510
E43 Unspecified severe protein-energy malnutrition
0.000 0.490 0.510
E42 Marasmic kwashiorkor
0.000 0.490 0.510
E41 Nutritional marasmus
0.000 0.490 0.510
E40 Kwashiorkor
0.000 0.490 0.510
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.493 0.507
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.493 0.507
E70.3 Albinism
0.000 0.493 0.507
E70.2 Disorders of tyrosine metabolism
0.000 0.493 0.507
E70.1 Other hyperphenylalaninaemias
0.000 0.493 0.507
E70.0 Classical phenylketonuria
0.000 0.493 0.507
E71.3 Disorders of fatty-acid metabolism
0.000 0.493 0.507
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.493 0.507
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.493 0.507
E71.0 Maple-syrup-urine disease
0.000 0.493 0.507
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.493 0.507
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.493 0.507
E72.5 Disorders of glycine metabolism
0.000 0.493 0.507
E72.4 Disorders of ornithine metabolism
0.000 0.493 0.507
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.493 0.507
E72.2 Disorders of urea cycle metabolism
0.000 0.493 0.507
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.493 0.507
E72.0 Disorders of amino-acid transport
0.000 0.493 0.507
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.493 0.507
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.493 0.507
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.493 0.507
E76.2 Other mucopolysaccharidoses
0.000 0.493 0.507
E76.1 Mucopolysaccharidosis, type II
0.000 0.493 0.507
E76.0 Mucopolysaccharidosis, type I
0.000 0.493 0.507
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.493 0.507
E77.8 Other disorders of glycoprotein metabolism
0.000 0.493 0.507
E77.1 Defects in glycoprotein degradation
0.000 0.493 0.507
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.493 0.507
E46 Unspecified protein-energy malnutrition
0.000 0.496 0.504
G37.5 Concentric sclerosis [Balo]
0.497 0.503 0.000
G37.4 Subacute necrotising myelitis
0.497 0.503 0.000
G37.2 Central pontine myelinolysis
0.497 0.503 0.000
G37.1 Central demyelination of corpus callosum
0.497 0.503 0.000
G37.0 Diffuse sclerosis
0.497 0.503 0.000
E74.0 Glycogen storage disease
0.000 0.505 0.495
E75.6 Lipid storage disorder, unspecified
0.000 0.506 0.493
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.506 0.493
E75.3 Sphingolipidosis, unspecified
0.000 0.506 0.493
E75.2 Other sphingolipidosis
0.000 0.506 0.493
E75.1 Other gangliosidosis
0.000 0.506 0.493
E75.0 GM2 gangliosidosis
0.000 0.506 0.493
E13.3 With ophthalmic complications
0.000 0.507 0.493
E84.8 Cystic fibrosis with other manifestations
0.000 0.514 0.486
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.514 0.486
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.514 0.486
K90.9 Intestinal malabsorption, unspecified
0.000 0.520 0.480
E75.5 Other lipid storage disorders
0.000 0.525 0.475
E83.3 Disorders of phosphorus metabolism
0.453 0.529 0.018
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.471 0.529 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.531 0.468
E11.6 With other specified complications
0.000 0.541 0.459
G36.0 Neuromyelitis optica [Devic]
0.459 0.541 0.000
E10.4 With neurological complications
0.000 0.542 0.458
E84.9 Cystic fibrosis, unspecified
0.000 0.543 0.457
K90.3 Pancreatic steatorrhoea
0.000 0.547 0.453
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.547 0.453
K90.1 Tropical sprue
0.000 0.547 0.453
E16.2 Hypoglycaemia, unspecified
0.000 0.550 0.450
K90.8 Other intestinal malabsorption
0.000 0.551 0.449
E16.1 Other hypoglycaemia
0.000 0.554 0.446
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.556 0.443
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.557 0.442
E11.4 With neurological complications
0.000 0.561 0.439
E83.9 Disorder of mineral metabolism, unspecified
0.397 0.564 0.039
E83.8 Other disorders of mineral metabolism
0.397 0.564 0.039
E83.2 Disorders of zinc metabolism
0.397 0.564 0.039
E83.0 Disorders of copper metabolism
0.397 0.564 0.039
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.572 0.428
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.572 0.428
E16.4 Abnormal secretion of gastrin
0.000 0.572 0.428
E16.3 Increased secretion of glucagon
0.000 0.572 0.428
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.572 0.428
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.573 0.427
L40-L45 Papulosquamous disorders
0.000 0.579 0.421
G36.9 Acute disseminated demyelination, unspecified
0.418 0.581 0.000
G36.8 Other specified acute disseminated demyelination
0.418 0.581 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.418 0.581 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.584 0.416
E89.4 Postprocedural ovarian failure
0.000 0.588 0.411
E73.8 Other lactose intolerance
0.000 0.597 0.403
E73.1 Secondary lactase deficiency
0.000 0.597 0.403
E73.0 Congenital lactase deficiency
0.000 0.597 0.403
M06 Other rheumatoid arthritis
0.000 0.602 0.398
E89.3 Postprocedural hypopituitarism
0.000 0.606 0.394
E88.9 Metabolic disorder, unspecified
0.000 0.609 0.391
E88.8 Other specified metabolic disorders
0.000 0.609 0.391
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.610 0.390
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.610 0.390
E89.5 Postprocedural testicular hypofunction
0.000 0.610 0.390
E89.1 Postprocedural hypoinsulinaemia
0.000 0.610 0.390
E06 Thyroiditis
0.000 0.615 0.385
E88.3 Tumour lysis syndrome
0.000 0.616 0.384
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.624 0.376
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.628 0.372
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.628 0.372
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.628 0.372
E44.1 Mild protein-energy malnutrition
0.000 0.634 0.366
E44.0 Moderate protein-energy malnutrition
0.000 0.634 0.366
E85.9 Amyloidosis, unspecified
0.000 0.635 0.364
E83.4 Disorders of magnesium metabolism
0.342 0.641 0.016
E65-E68 Obesity and other hyperalimentation
0.000 0.646 0.354
E85.8 Other amyloidosis
0.000 0.647 0.352
E20-E35 Disorders of other endocrine glands
0.000 0.650 0.350
M06.3 Rheumatoid nodule
0.000 0.658 0.342
E85.4 Organ-limited amyloidosis
0.000 0.668 0.331
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.674 0.325
L42 Pityriasis rosea
0.000 0.675 0.325
E89.2 Postprocedural hypoparathyroidism
0.000 0.683 0.317
E28 Ovarian dysfunction
0.000 0.691 0.309
L44 Other papulosquamous disorders
0.000 0.698 0.302
L41 Parapsoriasis
0.000 0.698 0.302
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.698 0.302
E85.3 Secondary systemic amyloidosis
0.001 0.700 0.299
L43 Lichen planus
0.000 0.704 0.296
E28.2 Polycystic ovarian syndrome
0.000 0.709 0.291
M06.4 Inflammatory polyarthropathy
0.000 0.709 0.290
M06.34 Rheumatoid nodule (Hand)
0.000 0.712 0.288
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.713 0.287
M06.2 Rheumatoid bursitis
0.000 0.715 0.285
M06.1 Adult-onset Still's disease
0.000 0.715 0.285
M06.8 Other specified rheumatoid arthritis
0.000 0.721 0.279
E50-E64 Other nutritional deficiencies
0.000 0.722 0.278
E23 Hypofunction and other disorders of pituitary gland
0.000 0.724 0.276
E06.5 Other chronic thyroiditis
0.000 0.724 0.276
E06.4 Drug-induced thyroiditis
0.000 0.724 0.276
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.724 0.276
E06.0 Acute thyroiditis
0.000 0.724 0.276
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.730 0.270
E06.1 Subacute thyroiditis
0.001 0.738 0.261
E24 Cushing's syndrome
0.000 0.740 0.260
E73.9 Lactose intolerance, unspecified
0.001 0.742 0.258
E67 Other hyperalimentation
0.000 0.746 0.254
E68 Sequelae of hyperalimentation
0.000 0.746 0.254
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.749 0.251
E32 Diseases of thymus
0.000 0.749 0.251
E31 Polyglandular dysfunction
0.000 0.749 0.251
E30 Disorders of puberty, not elsewhere classified
0.000 0.749 0.251
E25 Adrenogenital disorders
0.000 0.749 0.251
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.755 0.245
M06.38 Rheumatoid nodule (Other)
0.000 0.755 0.245
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.755 0.245
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.755 0.245
M06.33 Rheumatoid nodule (Forearm)
0.000 0.755 0.245
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.755 0.245
E83.5 Disorders of calcium metabolism
0.235 0.759 0.006
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.759 0.241
E21.3 Hyperparathyroidism, unspecified
0.000 0.760 0.240
L43.9 Lichen planus, unspecified
0.000 0.762 0.238
E26 Hyperaldosteronism
0.000 0.765 0.235
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.770 0.230
E23.7 Disorder of pituitary gland, unspecified
0.000 0.771 0.229
E28.9 Ovarian dysfunction, unspecified
0.000 0.778 0.222
E28.8 Other ovarian dysfunction
0.000 0.778 0.222
E28.1 Androgen excess
0.000 0.778 0.222
E28.0 Oestrogen excess
0.000 0.778 0.222
E11.3 With ophthalmic complications
0.000 0.779 0.221
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.779 0.221
E23.2 Diabetes insipidus
0.000 0.783 0.217
L41.9 Parapsoriasis, unspecified
0.000 0.783 0.216
L41.8 Other parapsoriasis
0.000 0.783 0.216
L41.5 Retiform parapsoriasis
0.000 0.783 0.216
L41.4 Large plaque parapsoriasis
0.000 0.783 0.216
L41.3 Small plaque parapsoriasis
0.000 0.783 0.216
L41.2 Lymphomatoid papulosis
0.000 0.783 0.216
L41.1 Pityriasis lichenoides chronica
0.000 0.783 0.216
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.783 0.216
L44.9 Papulosquamous disorder, unspecified
0.000 0.783 0.216
L44.8 Other specified papulosquamous disorders
0.000 0.783 0.216
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.783 0.216
L44.3 Lichen ruber moniliformis
0.000 0.783 0.216
L44.2 Lichen striatus
0.000 0.783 0.216
L44.1 Lichen nitidus
0.000 0.783 0.216
L44.0 Pityriasis rubra pilaris
0.000 0.783 0.216
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.784 0.216
L43.3 Subacute (active) lichen planus
0.000 0.788 0.212
L43.2 Lichenoid drug reaction
0.000 0.788 0.212
L43.1 Bullous lichen planus
0.000 0.788 0.212
L43.0 Hypertrophic lichen planus
0.000 0.788 0.212
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.791 0.208
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.791 0.208
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.791 0.208
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.791 0.208
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.791 0.208
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.791 0.208
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.791 0.208
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.791 0.208
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.795 0.205
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.795 0.205
M06.18 Adult-onset Still's disease (Other)
0.000 0.795 0.205
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.795 0.205
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.795 0.205
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.795 0.205
M06.14 Adult-onset Still's disease (Hand)
0.000 0.795 0.205
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.795 0.205
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.795 0.205
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.795 0.205
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.795 0.205
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.795 0.205
M06.28 Rheumatoid bursitis (Other)
0.000 0.795 0.205
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.795 0.205
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.795 0.205
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.795 0.205
M06.24 Rheumatoid bursitis (Hand)
0.000 0.795 0.205
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.795 0.205
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.795 0.205
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.795 0.205
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.795 0.205
E65 Localised adiposity
0.000 0.795 0.204
E20 Hypoparathyroidism
0.000 0.797 0.203
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.800 0.200
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.800 0.200
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.800 0.200
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.800 0.200
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.800 0.200
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.800 0.200
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.800 0.200
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.800 0.200
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.800 0.200
E24.2 Drug-induced Cushing's syndrome
0.000 0.800 0.200
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.800 0.199
E63 Other nutritional deficiencies
0.000 0.800 0.199
E50 Vitamin A deficiency
0.000 0.800 0.199
E60 Dietary zinc deficiency
0.000 0.800 0.199
E59 Dietary selenium deficiency
0.000 0.800 0.199
E54 Ascorbic acid deficiency
0.000 0.800 0.199
E52 Niacin deficiency [pellagra]
0.000 0.800 0.199
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.802 0.198
E23.1 Drug-induced hypopituitarism
0.000 0.802 0.198
E29 Testicular dysfunction
0.000 0.803 0.197
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.804 0.196
E56 Other vitamin deficiencies
0.000 0.805 0.194
E21.4 Other specified disorders of parathyroid gland
0.000 0.806 0.194
E21.2 Other hyperparathyroidism
0.000 0.806 0.194
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.807 0.193
E22 Hyperfunction of pituitary gland
0.000 0.807 0.192
E58 Dietary calcium deficiency
0.000 0.808 0.192
E51 Thiamine deficiency
0.000 0.809 0.191
M06.0 Seronegative rheumatoid arthritis
0.000 0.812 0.188
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.813 0.187
E24.8 Other Cushing's syndrome
0.000 0.814 0.186
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.814 0.186
E24.3 Ectopic ACTH syndrome
0.000 0.814 0.186
E24.1 Nelson's syndrome
0.000 0.814 0.186
E24.0 Pituitary-dependent Cushing's disease
0.000 0.814 0.186
E23.0 Hypopituitarism
0.000 0.817 0.183
E67.8 Other specified hyperalimentation
0.000 0.818 0.182
E67.3 Hypervitaminosis D
0.000 0.818 0.182
E67.2 Megavitamin-B6 syndrome
0.000 0.818 0.182
E67.1 Hypercarotenaemia
0.000 0.818 0.182
E67.0 Hypervitaminosis A
0.000 0.818 0.182
E24.9 Cushing's syndrome, unspecified
0.000 0.819 0.181
E23.6 Other disorders of pituitary gland
0.000 0.819 0.181
E06.3 Autoimmune thyroiditis
0.000 0.820 0.180
E25.9 Adrenogenital disorder, unspecified
0.000 0.820 0.180
E25.8 Other adrenogenital disorders
0.000 0.820 0.180
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.820 0.180
E30.9 Disorder of puberty, unspecified
0.000 0.820 0.180
E30.8 Other disorders of puberty
0.000 0.820 0.180
E30.1 Precocious puberty
0.000 0.820 0.180
E30.0 Delayed puberty
0.000 0.820 0.180
E31.9 Polyglandular dysfunction, unspecified
0.000 0.820 0.180
E31.8 Other polyglandular dysfunction
0.000 0.820 0.180
E31.1 Polyglandular hyperfunction
0.000 0.820 0.180
E31.0 Autoimmune polyglandular failure
0.000 0.820 0.180
E32.9 Disease of thymus, unspecified
0.000 0.820 0.180
E32.8 Other diseases of thymus
0.000 0.820 0.180
E32.1 Abscess of thymus
0.000 0.820 0.180
E32.0 Persistent hyperplasia of thymus
0.000 0.820 0.180
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.820 0.180
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.820 0.180
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.820 0.180
E06.9 Thyroiditis, unspecified
0.001 0.821 0.178
E61 Deficiency of other nutrient elements
0.000 0.822 0.178
E26.9 Hyperaldosteronism, unspecified
0.000 0.831 0.168
E26.8 Other hyperaldosteronism
0.000 0.831 0.168
E26.1 Secondary hyperaldosteronism
0.000 0.831 0.168
E28.3 Primary ovarian failure
0.000 0.832 0.168
L43.8 Other lichen planus
0.000 0.834 0.166
E34 Other endocrine disorders
0.001 0.840 0.159
E26.0 Primary hyperaldosteronism
0.000 0.847 0.152
E89.0 Postprocedural hypothyroidism
0.000 0.851 0.149
E20.8 Other hypoparathyroidism
0.000 0.854 0.146
E20.1 Pseudohypoparathyroidism
0.000 0.854 0.146
E20.0 Idiopathic hypoparathyroidism
0.000 0.854 0.146
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.854 0.146
E55 Vitamin D deficiency
0.000 0.855 0.145
K91.4 Colostomy and enterostomy malfunction
0.145 0.855 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.857 0.143
E50.8 Other manifestations of vitamin A deficiency
0.000 0.857 0.143
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.857 0.143
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.857 0.143
E50.5 Vitamin A deficiency with night blindness
0.000 0.857 0.143
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.857 0.143
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.857 0.143
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.857 0.143
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.857 0.143
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.857 0.143
E63.9 Nutritional deficiency, unspecified
0.000 0.857 0.143
E63.8 Other specified nutritional deficiencies
0.000 0.857 0.143
E63.1 Imbalance of constituents of food intake
0.000 0.857 0.143
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.857 0.143
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.857 0.143
E64.8 Sequelae of other nutritional deficiencies
0.000 0.857 0.143
E64.3 Sequelae of rickets
0.000 0.857 0.143
E64.2 Sequelae of vitamin C deficiency
0.000 0.857 0.143
E64.1 Sequelae of vitamin A deficiency
0.000 0.857 0.143
E64.0 Sequelae of protein-energy malnutrition
0.000 0.857 0.143
E29.9 Testicular dysfunction, unspecified
0.000 0.858 0.142
E29.8 Other testicular dysfunction
0.000 0.858 0.142
E29.0 Testicular hyperfunction
0.000 0.858 0.142
E56.9 Vitamin deficiency, unspecified
0.000 0.860 0.139
E56.8 Deficiency of other vitamins
0.000 0.860 0.139
E56.0 Deficiency of vitamin E
0.000 0.860 0.139
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.862 0.138
E22.8 Other hyperfunction of pituitary gland
0.000 0.862 0.138
E51.9 Thiamine deficiency, unspecified
0.000 0.863 0.137
E51.8 Other manifestations of thiamine deficiency
0.000 0.863 0.137
E51.1 Beriberi
0.000 0.863 0.137
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.865 0.135
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.865 0.135
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.865 0.135
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.865 0.135
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.865 0.135
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.865 0.135
E56.1 Deficiency of vitamin K
0.000 0.865 0.135
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.865 0.135
E51.2 Wernicke's encephalopathy
0.000 0.871 0.129
E61.9 Deficiency of nutrient element, unspecified
0.000 0.872 0.128
E61.8 Deficiency of other specified nutrient elements
0.000 0.872 0.128
E61.7 Deficiency of multiple nutrient elements
0.000 0.872 0.128
E61.6 Vanadium deficiency
0.000 0.872 0.128
E61.5 Molybdenum deficiency
0.000 0.872 0.128

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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