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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094573
log Bayes Factor = 34.7743
Chromosome 6   position 29,446,632  (GRCh37) Explore rs3094573 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.007 0.993
E10.9 Without complications
0.000 0.009 0.991
E10.3 With ophthalmic complications
0.000 0.023 0.977
E10.1 With ketoacidosis
0.000 0.043 0.957
E10.2 With renal complications
0.000 0.056 0.944
E10.4 With neurological complications
0.000 0.070 0.930
E13 Other specified diabetes mellitus
0.000 0.085 0.915
E11 Non-insulin-dependent diabetes mellitus
0.000 0.086 0.914
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.087 0.913
E11.2 With renal complications
0.000 0.103 0.897
E10.5 With peripheral circulatory complications
0.000 0.105 0.895
E20-E35 Disorders of other endocrine glands
0.000 0.112 0.888
E10.6 With other specified complications
0.000 0.117 0.883
E23 Hypofunction and other disorders of pituitary gland
0.000 0.133 0.867
E50-E64 Other nutritional deficiencies
0.000 0.151 0.849
E13.9 Without complications
0.000 0.154 0.846
E23.0 Hypopituitarism
0.000 0.162 0.838
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.179 0.821
E24 Cushing's syndrome
0.000 0.184 0.816
E14 Unspecified diabetes mellitus
0.000 0.218 0.782
E61 Deficiency of other nutrient elements
0.000 0.222 0.778
E11.5 With peripheral circulatory complications
0.000 0.232 0.768
E10.0 With coma
0.000 0.232 0.768
E11.0 With coma
0.000 0.234 0.766
E10.8 With unspecified complications
0.000 0.242 0.758
E16 Other disorders of pancreatic internal secretion
0.000 0.245 0.755
E61.1 Iron deficiency
0.000 0.269 0.731
E24.0 Pituitary-dependent Cushing's disease
0.000 0.270 0.730
E28 Ovarian dysfunction
0.000 0.275 0.725
E11.1 With ketoacidosis
0.000 0.278 0.722
E23.2 Diabetes insipidus
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.288 0.712
E25 Adrenogenital disorders
0.000 0.290 0.710
E13.3 With ophthalmic complications
0.000 0.296 0.703
E00-E07 Disorders of thyroid gland
0.000 0.314 0.686
E14.5 With peripheral circulatory complications
0.000 0.319 0.681
E20 Hypoparathyroidism
0.000 0.321 0.679
E16.1 Other hypoglycaemia
0.000 0.321 0.679
E23.7 Disorder of pituitary gland, unspecified
0.000 0.326 0.674
E51 Thiamine deficiency
0.000 0.340 0.660
E24.2 Drug-induced Cushing's syndrome
0.000 0.342 0.658
E14.4 With neurological complications
0.000 0.343 0.657
E13.8 With unspecified complications
0.000 0.344 0.656
E13.7 With multiple complications
0.000 0.344 0.656
E13.6 With other specified complications
0.000 0.344 0.656
E13.5 With peripheral circulatory complications
0.000 0.344 0.656
E13.4 With neurological complications
0.000 0.344 0.656
E13.2 With renal complications
0.000 0.344 0.656
E13.1 With ketoacidosis
0.000 0.344 0.656
E13.0 With coma
0.000 0.344 0.656
E11.7 With multiple complications
0.000 0.345 0.655
E11.8 With unspecified complications
0.000 0.345 0.655
E53 Deficiency of other B group vitamins
0.000 0.348 0.652
E56 Other vitamin deficiencies
0.000 0.348 0.652
E24.9 Cushing's syndrome, unspecified
0.000 0.355 0.645
E11.6 With other specified complications
0.000 0.362 0.638
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.363 0.637
E32 Diseases of thymus
0.000 0.363 0.637
E30 Disorders of puberty, not elsewhere classified
0.000 0.363 0.637
E16.2 Hypoglycaemia, unspecified
0.000 0.366 0.634
E55 Vitamin D deficiency
0.000 0.371 0.629
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.371 0.629
E28.3 Primary ovarian failure
0.000 0.376 0.624
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.378 0.622
E23.1 Drug-induced hypopituitarism
0.000 0.378 0.622
E07 Other disorders of thyroid
0.000 0.378 0.622
E29 Testicular dysfunction
0.000 0.379 0.621
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.391 0.609
E63 Other nutritional deficiencies
0.000 0.391 0.609
E50 Vitamin A deficiency
0.000 0.391 0.609
E60 Dietary zinc deficiency
0.000 0.391 0.609
E59 Dietary selenium deficiency
0.000 0.391 0.609
E54 Ascorbic acid deficiency
0.000 0.391 0.609
E52 Niacin deficiency [pellagra]
0.000 0.391 0.609
E14.1 With ketoacidosis
0.000 0.399 0.601
E23.6 Other disorders of pituitary gland
0.000 0.402 0.598
E40-E46 Malnutrition
0.000 0.411 0.589
E14.6 With other specified complications
0.000 0.411 0.589
E15 Nondiabetic hypoglycaemic coma
0.000 0.412 0.588
E31 Polyglandular dysfunction
0.000 0.414 0.586
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.415 0.585
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.415 0.585
E24.3 Ectopic ACTH syndrome
0.000 0.415 0.585
E24.1 Nelson's syndrome
0.000 0.415 0.585
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.418 0.582
E14.2 Withrenal complications
0.000 0.436 0.564
E27 Other disorders of adrenal gland
0.000 0.437 0.563
E14.7 With multiple complications
0.000 0.439 0.561
E14.0 With coma
0.000 0.439 0.561
E07.8 Other specified disorders of thyroid
0.000 0.440 0.560
E61.9 Deficiency of nutrient element, unspecified
0.000 0.442 0.558
E61.8 Deficiency of other specified nutrient elements
0.000 0.442 0.558
E61.7 Deficiency of multiple nutrient elements
0.000 0.442 0.558
E61.6 Vanadium deficiency
0.000 0.442 0.558
E61.5 Molybdenum deficiency
0.000 0.442 0.558
E61.4 Chromium deficiency
0.000 0.442 0.558
E61.3 Manganese deficiency
0.000 0.442 0.558
E61.0 Copper deficiency
0.000 0.442 0.558
E05.9 Thyrotoxicosis, unspecified
0.000 0.444 0.556
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.447 0.553
E34 Other endocrine disorders
0.000 0.449 0.551
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.459 0.541
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.459 0.541
E16.4 Abnormal secretion of gastrin
0.000 0.459 0.541
E16.3 Increased secretion of glucagon
0.000 0.459 0.541
E24.8 Other Cushing's syndrome
0.000 0.460 0.540
E61.2 Magnesium deficiency
0.000 0.460 0.539
E58 Dietary calcium deficiency
0.000 0.463 0.537
E20.9 Hypoparathyroidism, unspecified
0.000 0.470 0.530
E14.8 With unspecified complications
0.000 0.471 0.529
E51.2 Wernicke's encephalopathy
0.000 0.476 0.523
E28.9 Ovarian dysfunction, unspecified
0.000 0.480 0.520
E28.8 Other ovarian dysfunction
0.000 0.480 0.520
E28.1 Androgen excess
0.000 0.480 0.520
E28.0 Oestrogen excess
0.000 0.480 0.520
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.482 0.518
E12.9 Without complications
0.000 0.489 0.511
E12.8 With unspecified complications
0.000 0.489 0.511
E12.7 With multiple complications
0.000 0.489 0.511
E12.6 With other specified complications
0.000 0.489 0.511
E12.5 With peripheral circulatory complications
0.000 0.489 0.511
E12.4 With neurological complications
0.000 0.489 0.511
E12.3 With ophthalmic complications
0.000 0.489 0.511
E12.2 With renal complications
0.000 0.489 0.511
E12.1 With ketoacidosis
0.000 0.489 0.511
E12.0 With coma
0.000 0.489 0.511
E56.1 Deficiency of vitamin K
0.000 0.489 0.511
E26 Hyperaldosteronism
0.000 0.490 0.509
E25.9 Adrenogenital disorder, unspecified
0.000 0.491 0.509
E25.8 Other adrenogenital disorders
0.000 0.491 0.509
E27.1 Primary adrenocortical insufficiency
0.000 0.495 0.505
K51 Ulcerative colitis
0.501 0.499 0.000
K50 Crohn's disease [regional enteritis]
0.500 0.500 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.500 0.500
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.508 0.492
E00 Congenital iodine-deficiency syndrome
0.000 0.508 0.492
K50.9 Crohn's disease, unspecified
0.491 0.509 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.510 0.490
E11.4 With neurological complications
0.000 0.512 0.488
E20.8 Other hypoparathyroidism
0.000 0.513 0.487
E20.1 Pseudohypoparathyroidism
0.000 0.513 0.487
E20.0 Idiopathic hypoparathyroidism
0.000 0.513 0.487
K50-K52 Noninfective enteritis and colitis
0.487 0.513 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.513 0.487
K50.0 Crohn's disease of small intestine
0.482 0.518 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.519 0.481
K51.2 Ulcerative (chronic) proctitis
0.480 0.520 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.527 0.473
E51.8 Other manifestations of thiamine deficiency
0.000 0.527 0.473
E51.1 Beriberi
0.000 0.527 0.473
E22 Hyperfunction of pituitary gland
0.000 0.528 0.472
E55.9 Vitamin D deficiency, unspecified
0.000 0.528 0.472
E06 Thyroiditis
0.000 0.529 0.471
E34.8 Other specified endocrine disorders
0.000 0.532 0.468
E53.1 Pyridoxine deficiency
0.000 0.532 0.468
E53.0 Riboflavin deficiency
0.000 0.532 0.468
E56.9 Vitamin deficiency, unspecified
0.000 0.532 0.468
E56.8 Deficiency of other vitamins
0.000 0.532 0.468
E56.0 Deficiency of vitamin E
0.000 0.532 0.468
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.533 0.467
E30.9 Disorder of puberty, unspecified
0.000 0.543 0.457
E30.8 Other disorders of puberty
0.000 0.543 0.457
E30.1 Precocious puberty
0.000 0.543 0.457
E30.0 Delayed puberty
0.000 0.543 0.457
E32.9 Disease of thymus, unspecified
0.000 0.543 0.457
E32.8 Other diseases of thymus
0.000 0.543 0.457
E32.1 Abscess of thymus
0.000 0.543 0.457
E32.0 Persistent hyperplasia of thymus
0.000 0.543 0.457
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.543 0.457
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.543 0.457
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.543 0.457
K51.8 Other ulcerative colitis
0.455 0.545 0.000
K51.9 Ulcerative colitis, unspecified
0.454 0.546 0.000
E55.0 Rickets, active
0.000 0.549 0.451
E05.5 Thyroid crisis or storm
0.000 0.549 0.451
E05.4 Thyrotoxicosis factitia
0.000 0.549 0.451
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.549 0.451
E07.1 Dyshormogenetic goitre
0.000 0.554 0.446
E07.0 Hypersecretion of calcitonin
0.000 0.554 0.446
E29.9 Testicular dysfunction, unspecified
0.000 0.555 0.445
E29.8 Other testicular dysfunction
0.000 0.555 0.445
E29.0 Testicular hyperfunction
0.000 0.555 0.445
K50.8 Other Crohn's disease
0.440 0.560 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.563 0.437
E50.8 Other manifestations of vitamin A deficiency
0.000 0.563 0.437
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.563 0.437
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.563 0.437
E50.5 Vitamin A deficiency with night blindness
0.000 0.563 0.437
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.563 0.437
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.563 0.437
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.563 0.437
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.563 0.437
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.563 0.437
E63.9 Nutritional deficiency, unspecified
0.000 0.563 0.437
E63.8 Other specified nutritional deficiencies
0.000 0.563 0.437
E63.1 Imbalance of constituents of food intake
0.000 0.563 0.437
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.563 0.437
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.563 0.437
E64.8 Sequelae of other nutritional deficiencies
0.000 0.563 0.437
E64.3 Sequelae of rickets
0.000 0.563 0.437
E64.2 Sequelae of vitamin C deficiency
0.000 0.563 0.437
E64.1 Sequelae of vitamin A deficiency
0.000 0.563 0.437
E64.0 Sequelae of protein-energy malnutrition
0.000 0.563 0.437
E05.8 Other thyrotoxicosis
0.000 0.564 0.436
K51.0 Ulcerative (chronic) enterocolitis
0.431 0.569 0.000
E29.1 Testicular hypofunction
0.000 0.571 0.429
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.577 0.422
E45 Retarded development following protein-energy malnutrition
0.000 0.577 0.422
E43 Unspecified severe protein-energy malnutrition
0.000 0.577 0.422
E42 Marasmic kwashiorkor
0.000 0.577 0.422
E41 Nutritional marasmus
0.000 0.577 0.422
E40 Kwashiorkor
0.000 0.577 0.422
E31.9 Polyglandular dysfunction, unspecified
0.000 0.579 0.420
E31.8 Other polyglandular dysfunction
0.000 0.579 0.420
E31.1 Polyglandular hyperfunction
0.000 0.579 0.420
K51.3 Ulcerative (chronic) rectosigmoiditis
0.408 0.592 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.594 0.406
E27.5 Adrenomedullary hyperfunction
0.000 0.596 0.403
E27.0 Other adrenocortical overactivity
0.000 0.596 0.403
E06.9 Thyroiditis, unspecified
0.000 0.598 0.402
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.598 0.402
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.598 0.402
E21.4 Other specified disorders of parathyroid gland
0.000 0.604 0.396
E34.5 Androgen resistance syndrome
0.000 0.605 0.395
E34.4 Constitutional tall stature
0.000 0.605 0.395
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.605 0.395
E34.1 Other hypersecretion of intestinal hormones
0.000 0.605 0.395
E21.2 Other hyperparathyroidism
0.000 0.607 0.393
E21.3 Hyperparathyroidism, unspecified
0.000 0.611 0.389
E65-E68 Obesity and other hyperalimentation
0.000 0.612 0.388
K51.5 Mucosal proctocolitis
0.387 0.612 0.000
E14.3 With ophthalmic complications
0.000 0.616 0.384
E14.9 Without complications
0.000 0.616 0.384
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.625 0.375
K51.4 Pseudopolyposis of colon
0.373 0.627 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.630 0.370
E26.8 Other hyperaldosteronism
0.000 0.634 0.365
E26.1 Secondary hyperaldosteronism
0.000 0.634 0.365
E34.3 Short stature, not elsewhere classified
0.000 0.635 0.365
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.638 0.362
E27.9 Disorder of adrenal gland, unspecified
0.000 0.639 0.360
E26.9 Hyperaldosteronism, unspecified
0.000 0.641 0.359
E46 Unspecified protein-energy malnutrition
0.000 0.643 0.357
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.647 0.353
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.647 0.353
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.647 0.353
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.647 0.353
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.647 0.353
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.647 0.353
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.647 0.353
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.647 0.353
E22.0 Acromegaly and pituitary gigantism
0.000 0.647 0.353
E21.0 Primary hyperparathyroidism
0.000 0.653 0.347
K50.1 Crohn's disease of large intestine
0.344 0.656 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.661 0.339
E22.8 Other hyperfunction of pituitary gland
0.000 0.661 0.339
E06.1 Subacute thyroiditis
0.000 0.662 0.338
E06.4 Drug-induced thyroiditis
0.000 0.662 0.338
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.662 0.338
E06.0 Acute thyroiditis
0.000 0.662 0.338
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.666 0.334
K51.1 Ulcerative (chronic) ileocolitis
0.332 0.668 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.678 0.322
K90 Intestinal malabsorption
0.002 0.683 0.315
E34.0 Carcinoid syndrome
0.000 0.693 0.307
E34.9 Endocrine disorder, unspecified
0.000 0.693 0.307
E44.1 Mild protein-energy malnutrition
0.000 0.697 0.303
E44.0 Moderate protein-energy malnutrition
0.000 0.697 0.303
E06.5 Other chronic thyroiditis
0.000 0.699 0.301
E27.2 Addisonian crisis
0.000 0.709 0.290
E67 Other hyperalimentation
0.000 0.722 0.278
E68 Sequelae of hyperalimentation
0.000 0.722 0.278
E03 Other hypothyroidism
0.000 0.736 0.264
E22.1 Hyperprolactinaemia
0.000 0.737 0.262
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.740 0.260
E65 Localised adiposity
0.000 0.745 0.255
E26.0 Primary hyperaldosteronism
0.000 0.750 0.249
E06.3 Autoimmune thyroiditis
0.000 0.761 0.239
K90.9 Intestinal malabsorption, unspecified
0.001 0.767 0.232
K90.8 Other intestinal malabsorption
0.001 0.768 0.231
E11.3 With ophthalmic complications
0.000 0.771 0.229
K90.3 Pancreatic steatorrhoea
0.002 0.773 0.226
K90.2 Blind loop syndrome, not elsewhere classified
0.002 0.773 0.226
K90.1 Tropical sprue
0.002 0.773 0.226
E03.8 Other specified hypothyroidism
0.000 0.791 0.209
E67.8 Other specified hyperalimentation
0.000 0.800 0.200
E67.3 Hypervitaminosis D
0.000 0.800 0.200
E67.2 Megavitamin-B6 syndrome
0.000 0.800 0.200
E67.1 Hypercarotenaemia
0.000 0.800 0.200
E67.0 Hypervitaminosis A
0.000 0.800 0.200
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.805 0.195
E03.1 Congenital hypothyroidism without goitre
0.000 0.807 0.192
E03.5 Myxoedema coma
0.000 0.811 0.189
E03.4 Atrophy of thyroid (acquired)
0.000 0.811 0.189
E03.3 Postinfectious hypothyroidism
0.000 0.811 0.189
E11.9 Without complications
0.000 0.836 0.164
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.002 0.851 0.147
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.870 0.130
Z99.1 Dependence on respirator
0.000 0.882 0.118
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.117 0.883 0.000
E83 Disorders of mineral metabolism
0.112 0.884 0.004
K40 Inguinal hernia
0.114 0.886 0.000
K43 Ventral hernia
0.110 0.890 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.109 0.891 0.000
K40-K46 Hernia
0.105 0.895 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.104 0.896 0.000
K41 Femoral hernia
0.099 0.901 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.099 0.901 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.098 0.902 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.091 0.909 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.090 0.910 0.000
E04 Other non-toxic goitre
0.000 0.915 0.085
E83.9 Disorder of mineral metabolism, unspecified
0.080 0.917 0.003
E83.8 Other disorders of mineral metabolism
0.080 0.917 0.003
E83.2 Disorders of zinc metabolism
0.080 0.917 0.003
E83.0 Disorders of copper metabolism
0.080 0.917 0.003
K40.1 Bilateral inguinal hernia, with gangrene
0.082 0.918 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.079 0.921 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.079 0.921 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.079 0.921 0.000
K43.4 Parastomal hernia with gangrene
0.079 0.921 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.079 0.921 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.079 0.921 0.000
K43.1 Ventral hernia with gangrene
0.079 0.921 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.078 0.922 0.000
E66 Obesity
0.000 0.923 0.077
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.077 0.923 0.000
E83.3 Disorders of phosphorus metabolism
0.075 0.923 0.002
K41.1 Bilateral femoral hernia, with gangrene
0.071 0.929 0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.071 0.929 0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.071 0.929 0.000
F45.8 Other somatoform disorders
0.000 0.930 0.070
K46 Unspecified abdominal hernia
0.069 0.931 0.000
N84.1 Polyp of cervix uteri
0.066 0.934 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.065 0.935 0.000
L40.9 Psoriasis, unspecified
0.000 0.938 0.062
E04.8 Other specified non-toxic goitre
0.000 0.939 0.061
E83.4 Disorders of magnesium metabolism
0.057 0.942 0.001
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.944 0.056
E04.9 Non-toxic goitre, unspecified
0.000 0.944 0.056
E66.1 Drug-induced obesity
0.000 0.944 0.055
Z99.8 Dependence on other enabling machines and devices
0.000 0.945 0.055
E66.0 Obesity due to excess calories
0.000 0.945 0.055
K46.1 Unspecified abdominal hernia with gangrene
0.050 0.950 0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.048 0.952 0.000
L40 Psoriasis
0.000 0.953 0.047
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.046 0.954 0.000
K52 Other non-infective gastro-enteritis and colitis
0.044 0.955 0.001
K45 Other abdominal hernia
0.045 0.955 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.956 0.044
E04.0 Non-toxic diffuse goitre
0.000 0.956 0.044
L40.5 Arthropathic psoriasis
0.000 0.956 0.044
E66.8 Other obesity
0.000 0.959 0.041
F45 Somatoform disorders
0.000 0.959 0.041
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.960 0.040
Z99.4 Dependence on artificial heart
0.000 0.960 0.040
Z99.0 Dependence on aspirator
0.000 0.960 0.040
L43.9 Lichen planus, unspecified
0.000 0.960 0.040
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.960 0.040
L43 Lichen planus
0.000 0.961 0.039
E70-E90 Metabolic disorders
0.000 0.961 0.038
L40-L45 Papulosquamous disorders
0.000 0.962 0.038
E73 Lactose intolerance
0.000 0.962 0.038
E73.9 Lactose intolerance, unspecified
0.000 0.962 0.038
K52.0 Gastro-enteritis and colitis due to radiation
0.037 0.963 0.000
L40.1 Generalised pustular psoriasis
0.000 0.963 0.037
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.965 0.035
L40.2 Acrodermatitis continua
0.000 0.966 0.034
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.967 0.033
K44 Diaphragmatic hernia
0.033 0.967 0.000
F45.9 Somatoform disorder, unspecified
0.000 0.967 0.033
K45.1 Other specified abdominal hernia with gangrene
0.032 0.967 0.000
F45.2 Hypochondriacal disorder
0.000 0.968 0.032
E74 Other disorders of carbohydrate metabolism
0.000 0.969 0.031
L40.4 Guttate psoriasis
0.000 0.969 0.030
F45.0 Somatisation disorder
0.000 0.970 0.030
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.970 0.030
F45.4 Persistent somatoform pain disorder
0.000 0.970 0.030
L43.8 Other lichen planus
0.000 0.970 0.030
F45.1 Undifferentiated somatoform disorder
0.000 0.970 0.029
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.028 0.971 0.001
E84 Cystic fibrosis
0.000 0.971 0.029
E79 Disorders of purine and pyrimidine metabolism
0.000 0.971 0.029
K42 Umbilical hernia
0.028 0.972 0.000
L43.3 Subacute (active) lichen planus
0.000 0.972 0.028
L43.2 Lichenoid drug reaction
0.000 0.972 0.028
L43.1 Bullous lichen planus
0.000 0.972 0.028
L43.0 Hypertrophic lichen planus
0.000 0.972 0.028
E72 Other disorders of amino-acid metabolism
0.000 0.972 0.028
K52.3 Indeterminate colitis
0.027 0.972 0.001
E77 Disorders of glycoprotein metabolism
0.000 0.972 0.028
E76 Disorders of glycosaminoglycan metabolism
0.000 0.972 0.028
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.972 0.028
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.972 0.028
E70 Disorders of aromatic amino-acid metabolism
0.000 0.972 0.028
L41 Parapsoriasis
0.000 0.973 0.027
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.973 0.027
E73.8 Other lactose intolerance
0.000 0.973 0.027
E73.1 Secondary lactase deficiency
0.000 0.973 0.027
E73.0 Congenital lactase deficiency
0.000 0.973 0.027
F45.3 Somatoform autonomic dysfunction
0.000 0.973 0.027
Z99.2 Dependence on renal dialysis
0.000 0.973 0.027
L40.8 Other psoriasis
0.000 0.973 0.026
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.026 0.973 0.001
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.974 0.026
L44 Other papulosquamous disorders
0.000 0.974 0.026
E85 Amyloidosis
0.000 0.974 0.026
K90-K93 Other diseases of the digestive system
0.007 0.974 0.019
L40.3 Pustulosis palmaris et plantaris
0.000 0.974 0.025
Chapter XI Diseases of the digestive system
0.025 0.975 0.000
E88 Other metabolic disorders
0.000 0.975 0.025
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.975 0.025
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.975 0.025
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.975 0.025
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.975 0.025
K44.1 Diaphragmatic hernia with gangrene
0.025 0.975 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.975 0.025
E75.5 Other lipid storage disorders
0.000 0.976 0.024
R31 Unspecified haematuria
0.024 0.976 0.000
L40.0 Psoriasis vulgaris
0.000 0.977 0.023
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.977 0.023
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.977 0.023
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.977 0.023
E74.2 Disorders of galactose metabolism
0.000 0.977 0.023
E74.1 Disorders of fructose metabolism
0.000 0.977 0.023
E74.0 Glycogen storage disease
0.000 0.977 0.023
E84.9 Cystic fibrosis, unspecified
0.000 0.977 0.022
E85.4 Organ-limited amyloidosis
0.000 0.977 0.022
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.978 0.022
E75.6 Lipid storage disorder, unspecified
0.000 0.978 0.022
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.978 0.022
E75.3 Sphingolipidosis, unspecified
0.000 0.978 0.022
E75.2 Other sphingolipidosis
0.000 0.978 0.022
E75.1 Other gangliosidosis
0.000 0.978 0.022
E75.0 GM2 gangliosidosis
0.000 0.978 0.022
K42.1 Umbilical hernia with gangrene
0.022 0.978 0.000
E84.8 Cystic fibrosis with other manifestations
0.000 0.979 0.021
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.979 0.021
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.979 0.021
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.979 0.021
E79.1 Lesch-Nyhan syndrome
0.000 0.979 0.021
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.979 0.021
K52.1 Toxic gastro-enteritis and colitis
0.020 0.979 0.001
E72.0 Disorders of amino-acid transport
0.000 0.979 0.020
L42 Pityriasis rosea
0.000 0.980 0.020
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.980 0.020
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.980 0.020
E72.5 Disorders of glycine metabolism
0.000 0.980 0.020
E72.4 Disorders of ornithine metabolism
0.000 0.980 0.020
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.980 0.020
E72.2 Disorders of urea cycle metabolism
0.000 0.980 0.020
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.980 0.020
E71.3 Disorders of fatty-acid metabolism
0.000 0.980 0.020
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.980 0.020
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.980 0.020
E71.0 Maple-syrup-urine disease
0.000 0.980 0.020
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.980 0.020
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.980 0.020
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.980 0.020
E76.2 Other mucopolysaccharidoses
0.000 0.980 0.020
E76.1 Mucopolysaccharidosis, type II
0.000 0.980 0.020
E76.0 Mucopolysaccharidosis, type I
0.000 0.980 0.020
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.980 0.020
E77.8 Other disorders of glycoprotein metabolism
0.000 0.980 0.020
E77.1 Defects in glycoprotein degradation
0.000 0.980 0.020
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.980 0.020
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.980 0.020
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.980 0.020
E70.2 Disorders of tyrosine metabolism
0.000 0.980 0.020
E70.1 Other hyperphenylalaninaemias
0.000 0.980 0.020
E70.0 Classical phenylketonuria
0.000 0.980 0.020
E70.3 Albinism
0.000 0.980 0.020
L41.9 Parapsoriasis, unspecified
0.000 0.980 0.020
L41.8 Other parapsoriasis
0.000 0.980 0.020
L41.5 Retiform parapsoriasis
0.000 0.980 0.020
L41.4 Large plaque parapsoriasis
0.000 0.980 0.020
L41.3 Small plaque parapsoriasis
0.000 0.980 0.020
L41.2 Lymphomatoid papulosis
0.000 0.980 0.020
L41.1 Pityriasis lichenoides chronica
0.000 0.980 0.020
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.980 0.020
M31.6 Other giant cell arteritis
0.000 0.980 0.020
E88.2 Lipomatosis, not elsewhere classified
0.000 0.981 0.019
L44.9 Papulosquamous disorder, unspecified
0.000 0.981 0.019
L44.8 Other specified papulosquamous disorders
0.000 0.981 0.019
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.981 0.019
L44.3 Lichen ruber moniliformis
0.000 0.981 0.019
L44.2 Lichen striatus
0.000 0.981 0.019
L44.1 Lichen nitidus
0.000 0.981 0.019
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.981 0.019
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.981 0.019
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.981 0.019
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.981 0.019
E83.5 Disorders of calcium metabolism
0.018 0.981 0.001
K93 Disorders of other digestive organs in diseases classified elsewhere
0.005 0.981 0.014
E88.9 Metabolic disorder, unspecified
0.000 0.981 0.018
E85.8 Other amyloidosis
0.000 0.982 0.018

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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