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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094574
log Bayes Factor = 35.1145
Chromosome 6   position 29,422,092  (GRCh37) Explore rs3094574 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.007 0.993
E10-E14 Diabetes mellitus
0.000 0.008 0.992
E10.3 With ophthalmic complications
0.000 0.025 0.975
E10.1 With ketoacidosis
0.000 0.044 0.956
E10.2 With renal complications
0.000 0.047 0.953
E13 Other specified diabetes mellitus
0.000 0.056 0.944
E10.4 With neurological complications
0.000 0.095 0.905
E13.9 Without complications
0.000 0.099 0.901
K51 Ulcerative colitis
0.900 0.100 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.108 0.892
E10.5 With peripheral circulatory complications
0.000 0.109 0.891
E11 Non-insulin-dependent diabetes mellitus
0.000 0.122 0.878
K51.2 Ulcerative (chronic) proctitis
0.875 0.125 0.000
E11.2 With renal complications
0.000 0.142 0.858
E10.6 With other specified complications
0.000 0.142 0.858
K51.9 Ulcerative colitis, unspecified
0.856 0.144 0.000
K50-K52 Noninfective enteritis and colitis
0.853 0.147 0.000
K50 Crohn's disease [regional enteritis]
0.852 0.148 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.848 0.152 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.155 0.845
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.166 0.834
K50.0 Crohn's disease of small intestine
0.833 0.167 0.000
E50-E64 Other nutritional deficiencies
0.000 0.173 0.827
K50.9 Crohn's disease, unspecified
0.826 0.174 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.180 0.820
K51.8 Other ulcerative colitis
0.814 0.186 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.207 0.793
E24 Cushing's syndrome
0.000 0.212 0.788
E23.0 Hypopituitarism
0.000 0.213 0.787
K51.0 Ulcerative (chronic) enterocolitis
0.784 0.216 0.000
E10.0 With coma
0.000 0.219 0.781
E10.7 With multiple complications
0.000 0.227 0.773
K51.5 Mucosal proctocolitis
0.761 0.239 0.000
E14 Unspecified diabetes mellitus
0.000 0.242 0.758
E61 Deficiency of other nutrient elements
0.000 0.254 0.746
E11.0 With coma
0.000 0.261 0.739
E11.5 With peripheral circulatory complications
0.000 0.269 0.731
E13.3 With ophthalmic complications
0.000 0.273 0.727
E16.1 Other hypoglycaemia
0.000 0.279 0.721
E12 Malnutrition-related diabetes mellitus
0.000 0.289 0.711
E16.2 Hypoglycaemia, unspecified
0.000 0.289 0.711
E24.0 Pituitary-dependent Cushing's disease
0.000 0.291 0.709
E61.1 Iron deficiency
0.000 0.310 0.690
E23.2 Diabetes insipidus
0.000 0.314 0.686
E10.8 With unspecified complications
0.000 0.315 0.685
E00-E07 Disorders of thyroid gland
0.000 0.316 0.684
K51.4 Pseudopolyposis of colon
0.680 0.320 0.000
E25 Adrenogenital disorders
0.000 0.320 0.680
E13.8 With unspecified complications
0.000 0.323 0.677
E13.7 With multiple complications
0.000 0.323 0.677
E13.6 With other specified complications
0.000 0.323 0.677
E13.5 With peripheral circulatory complications
0.000 0.323 0.677
E13.4 With neurological complications
0.000 0.323 0.677
E13.2 With renal complications
0.000 0.323 0.677
E13.1 With ketoacidosis
0.000 0.323 0.677
E13.0 With coma
0.000 0.323 0.677
K50.8 Other Crohn's disease
0.665 0.335 0.000
E55 Vitamin D deficiency
0.000 0.342 0.658
E14.5 With peripheral circulatory complications
0.000 0.348 0.652
E51 Thiamine deficiency
0.000 0.352 0.648
E24.2 Drug-induced Cushing's syndrome
0.000 0.356 0.644
E11.1 With ketoacidosis
0.000 0.358 0.642
E07 Other disorders of thyroid
0.000 0.361 0.639
E24.9 Cushing's syndrome, unspecified
0.000 0.367 0.633
E28 Ovarian dysfunction
0.000 0.367 0.633
E11.7 With multiple complications
0.000 0.370 0.630
E53 Deficiency of other B group vitamins
0.000 0.371 0.629
E20 Hypoparathyroidism
0.000 0.374 0.626
E56 Other vitamin deficiencies
0.000 0.378 0.622
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.379 0.621
E23.7 Disorder of pituitary gland, unspecified
0.000 0.385 0.615
E11.6 With other specified complications
0.000 0.389 0.611
E14.4 With neurological complications
0.000 0.393 0.607
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.394 0.606
E32 Diseases of thymus
0.000 0.394 0.606
E30 Disorders of puberty, not elsewhere classified
0.000 0.394 0.606
E15 Nondiabetic hypoglycaemic coma
0.000 0.402 0.598
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.407 0.593
E63 Other nutritional deficiencies
0.000 0.407 0.593
E50 Vitamin A deficiency
0.000 0.407 0.593
E60 Dietary zinc deficiency
0.000 0.407 0.593
E59 Dietary selenium deficiency
0.000 0.407 0.593
E54 Ascorbic acid deficiency
0.000 0.407 0.593
E52 Niacin deficiency [pellagra]
0.000 0.407 0.593
E07.8 Other specified disorders of thyroid
0.000 0.409 0.591
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.412 0.588
E23.1 Drug-induced hypopituitarism
0.000 0.412 0.588
E23.6 Other disorders of pituitary gland
0.000 0.415 0.585
K51.1 Ulcerative (chronic) ileocolitis
0.585 0.415 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.421 0.579
E14.6 With other specified complications
0.000 0.422 0.578
E11.8 With unspecified complications
0.000 0.423 0.576
E11.4 With neurological complications
0.000 0.426 0.574
E14.1 With ketoacidosis
0.000 0.430 0.570
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.431 0.569
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.431 0.569
E16.4 Abnormal secretion of gastrin
0.000 0.431 0.569
E16.3 Increased secretion of glucagon
0.000 0.431 0.569
E29 Testicular dysfunction
0.000 0.433 0.567
E40-E46 Malnutrition
0.000 0.433 0.567
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.435 0.565
E24.3 Ectopic ACTH syndrome
0.000 0.435 0.565
E24.1 Nelson's syndrome
0.000 0.435 0.565
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.438 0.562
E31 Polyglandular dysfunction
0.000 0.439 0.561
E27 Other disorders of adrenal gland
0.000 0.450 0.550
E28.3 Primary ovarian failure
0.000 0.454 0.546
E14.7 With multiple complications
0.000 0.457 0.543
E14.0 With coma
0.000 0.457 0.543
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.461 0.539
E55.9 Vitamin D deficiency, unspecified
0.000 0.463 0.537
K50.1 Crohn's disease of large intestine
0.535 0.465 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.465 0.535
E61.8 Deficiency of other specified nutrient elements
0.000 0.465 0.535
E61.7 Deficiency of multiple nutrient elements
0.000 0.465 0.535
E61.6 Vanadium deficiency
0.000 0.465 0.535
E61.5 Molybdenum deficiency
0.000 0.465 0.535
E61.4 Chromium deficiency
0.000 0.465 0.535
E61.3 Manganese deficiency
0.000 0.465 0.535
E61.0 Copper deficiency
0.000 0.465 0.535
E61.2 Magnesium deficiency
0.000 0.472 0.528
E05.9 Thyrotoxicosis, unspecified
0.000 0.472 0.528
E14.2 Withrenal complications
0.000 0.473 0.527
E24.8 Other Cushing's syndrome
0.000 0.474 0.526
E14.8 With unspecified complications
0.000 0.478 0.522
E51.2 Wernicke's encephalopathy
0.000 0.481 0.519
E07.9 Disorder of thyroid, unspecified
0.000 0.484 0.516
E27.1 Primary adrenocortical insufficiency
0.000 0.490 0.510
E12.9 Without complications
0.000 0.490 0.510
E12.8 With unspecified complications
0.000 0.490 0.510
E12.7 With multiple complications
0.000 0.490 0.510
E12.6 With other specified complications
0.000 0.490 0.510
E12.5 With peripheral circulatory complications
0.000 0.490 0.510
E12.4 With neurological complications
0.000 0.490 0.510
E12.3 With ophthalmic complications
0.000 0.490 0.510
E12.2 With renal complications
0.000 0.490 0.510
E12.1 With ketoacidosis
0.000 0.490 0.510
E12.0 With coma
0.000 0.490 0.510
E34 Other endocrine disorders
0.000 0.494 0.506
E58 Dietary calcium deficiency
0.000 0.500 0.500
E53.8 Deficiency of other specified B group vitamins
0.000 0.504 0.496
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.510 0.490
E00 Congenital iodine-deficiency syndrome
0.000 0.510 0.490
E25.9 Adrenogenital disorder, unspecified
0.000 0.512 0.488
E25.8 Other adrenogenital disorders
0.000 0.512 0.488
E26 Hyperaldosteronism
0.000 0.521 0.479
E56.1 Deficiency of vitamin K
0.000 0.525 0.475
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.527 0.473
E55.0 Rickets, active
0.000 0.528 0.472
E20.9 Hypoparathyroidism, unspecified
0.000 0.530 0.469
E51.9 Thiamine deficiency, unspecified
0.000 0.535 0.464
E51.8 Other manifestations of thiamine deficiency
0.000 0.535 0.464
E51.1 Beriberi
0.000 0.535 0.464
E14.9 Without complications
0.000 0.540 0.460
E07.1 Dyshormogenetic goitre
0.000 0.542 0.458
E07.0 Hypersecretion of calcitonin
0.000 0.542 0.458
E28.9 Ovarian dysfunction, unspecified
0.000 0.546 0.454
E28.8 Other ovarian dysfunction
0.000 0.546 0.454
E28.1 Androgen excess
0.000 0.546 0.454
E28.0 Oestrogen excess
0.000 0.546 0.454
E53.1 Pyridoxine deficiency
0.000 0.549 0.451
E53.0 Riboflavin deficiency
0.000 0.549 0.451
E20.8 Other hypoparathyroidism
0.000 0.551 0.449
E20.1 Pseudohypoparathyroidism
0.000 0.551 0.449
E20.0 Idiopathic hypoparathyroidism
0.000 0.551 0.449
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.554 0.446
E56.9 Vitamin deficiency, unspecified
0.000 0.554 0.446
E56.8 Deficiency of other vitamins
0.000 0.554 0.446
E56.0 Deficiency of vitamin E
0.000 0.554 0.446
E05.5 Thyroid crisis or storm
0.000 0.554 0.446
E05.4 Thyrotoxicosis factitia
0.000 0.554 0.446
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.554 0.446
E06 Thyroiditis
0.000 0.559 0.441
E05.8 Other thyrotoxicosis
0.000 0.559 0.441
E22 Hyperfunction of pituitary gland
0.000 0.560 0.440
E53.9 Vitamin B deficiency, unspecified
0.000 0.561 0.439
E30.9 Disorder of puberty, unspecified
0.000 0.566 0.434
E30.8 Other disorders of puberty
0.000 0.566 0.434
E30.1 Precocious puberty
0.000 0.566 0.434
E30.0 Delayed puberty
0.000 0.566 0.434
E32.9 Disease of thymus, unspecified
0.000 0.566 0.434
E32.8 Other diseases of thymus
0.000 0.566 0.434
E32.1 Abscess of thymus
0.000 0.566 0.434
E32.0 Persistent hyperplasia of thymus
0.000 0.566 0.434
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.566 0.434
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.566 0.434
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.566 0.434
E34.8 Other specified endocrine disorders
0.000 0.573 0.426
E50.9 Vitamin A deficiency, unspecified
0.000 0.575 0.425
E50.8 Other manifestations of vitamin A deficiency
0.000 0.575 0.425
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.575 0.425
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.575 0.425
E50.5 Vitamin A deficiency with night blindness
0.000 0.575 0.425
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.575 0.425
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.575 0.425
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.575 0.425
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.575 0.425
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.575 0.425
E63.9 Nutritional deficiency, unspecified
0.000 0.575 0.425
E63.8 Other specified nutritional deficiencies
0.000 0.575 0.425
E63.1 Imbalance of constituents of food intake
0.000 0.575 0.425
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.575 0.425
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.575 0.425
E64.8 Sequelae of other nutritional deficiencies
0.000 0.575 0.425
E64.3 Sequelae of rickets
0.000 0.575 0.425
E64.2 Sequelae of vitamin C deficiency
0.000 0.575 0.425
E64.1 Sequelae of vitamin A deficiency
0.000 0.575 0.425
E64.0 Sequelae of protein-energy malnutrition
0.000 0.575 0.425
E29.9 Testicular dysfunction, unspecified
0.000 0.593 0.407
E29.8 Other testicular dysfunction
0.000 0.593 0.407
E29.0 Testicular hyperfunction
0.000 0.593 0.407
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.593 0.406
E45 Retarded development following protein-energy malnutrition
0.000 0.593 0.406
E43 Unspecified severe protein-energy malnutrition
0.000 0.593 0.406
E42 Marasmic kwashiorkor
0.000 0.593 0.406
E41 Nutritional marasmus
0.000 0.593 0.406
E40 Kwashiorkor
0.000 0.593 0.406
E31.9 Polyglandular dysfunction, unspecified
0.000 0.598 0.402
E31.8 Other polyglandular dysfunction
0.000 0.598 0.402
E31.1 Polyglandular hyperfunction
0.000 0.598 0.402
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.600 0.400
E27.5 Adrenomedullary hyperfunction
0.000 0.606 0.394
E27.0 Other adrenocortical overactivity
0.000 0.606 0.394
E27.8 Other specified disorders of adrenal gland
0.000 0.620 0.380
E65-E68 Obesity and other hyperalimentation
0.000 0.620 0.380
E06.9 Thyroiditis, unspecified
0.000 0.624 0.376
E29.1 Testicular hypofunction
0.000 0.632 0.368
E34.5 Androgen resistance syndrome
0.000 0.637 0.363
E34.4 Constitutional tall stature
0.000 0.637 0.363
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.637 0.363
E34.1 Other hypersecretion of intestinal hormones
0.000 0.637 0.363
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.639 0.361
E31.0 Autoimmune polyglandular failure
0.000 0.642 0.357
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.645 0.355
E14.3 With ophthalmic complications
0.000 0.646 0.354
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.648 0.352
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.648 0.352
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.648 0.352
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.648 0.352
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.648 0.352
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.648 0.352
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.648 0.352
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.648 0.352
E27.9 Disorder of adrenal gland, unspecified
0.000 0.649 0.351
E26.8 Other hyperaldosteronism
0.000 0.656 0.343
E26.1 Secondary hyperaldosteronism
0.000 0.656 0.343
E26.9 Hyperaldosteronism, unspecified
0.000 0.659 0.341
E34.3 Short stature, not elsewhere classified
0.000 0.661 0.338
E46 Unspecified protein-energy malnutrition
0.000 0.666 0.334
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.671 0.329
E28.2 Polycystic ovarian syndrome
0.000 0.678 0.322
E21.4 Other specified disorders of parathyroid gland
0.000 0.680 0.320
E06.1 Subacute thyroiditis
0.000 0.681 0.319
E06.4 Drug-induced thyroiditis
0.000 0.683 0.317
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.683 0.317
E06.0 Acute thyroiditis
0.000 0.683 0.317
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.684 0.315
E22.8 Other hyperfunction of pituitary gland
0.000 0.684 0.315
E22.0 Acromegaly and pituitary gigantism
0.000 0.685 0.315
K90 Intestinal malabsorption
0.001 0.692 0.308
E21.2 Other hyperparathyroidism
0.000 0.695 0.305
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.698 0.302
E21.0 Primary hyperparathyroidism
0.000 0.705 0.295
E44.1 Mild protein-energy malnutrition
0.000 0.708 0.291
E44.0 Moderate protein-energy malnutrition
0.000 0.708 0.291
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.714 0.286
E34.0 Carcinoid syndrome
0.000 0.720 0.280
E67 Other hyperalimentation
0.000 0.727 0.272
E68 Sequelae of hyperalimentation
0.000 0.727 0.272
E34.9 Endocrine disorder, unspecified
0.000 0.728 0.272
E06.5 Other chronic thyroiditis
0.000 0.728 0.272
E27.2 Addisonian crisis
0.000 0.739 0.260
E22.1 Hyperprolactinaemia
0.000 0.740 0.259
E65 Localised adiposity
0.000 0.748 0.252
E21.3 Hyperparathyroidism, unspecified
0.000 0.753 0.247
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.759 0.240
E03 Other hypothyroidism
0.000 0.768 0.232
E26.0 Primary hyperaldosteronism
0.001 0.777 0.222
K90.8 Other intestinal malabsorption
0.000 0.778 0.221
K90.3 Pancreatic steatorrhoea
0.001 0.779 0.221
K90.2 Blind loop syndrome, not elsewhere classified
0.001 0.779 0.221
K90.1 Tropical sprue
0.001 0.779 0.221
K90.9 Intestinal malabsorption, unspecified
0.000 0.780 0.220
E67.8 Other specified hyperalimentation
0.000 0.804 0.195
E67.3 Hypervitaminosis D
0.000 0.804 0.195
E67.2 Megavitamin-B6 syndrome
0.000 0.804 0.195
E67.1 Hypercarotenaemia
0.000 0.804 0.195
E67.0 Hypervitaminosis A
0.000 0.804 0.195
E06.3 Autoimmune thyroiditis
0.000 0.807 0.193
E11.3 With ophthalmic complications
0.000 0.812 0.188
E03.8 Other specified hypothyroidism
0.000 0.825 0.175
E03.1 Congenital hypothyroidism without goitre
0.000 0.829 0.171
E11.9 Without complications
0.000 0.833 0.167
E03.5 Myxoedema coma
0.000 0.834 0.166
E03.4 Atrophy of thyroid (acquired)
0.000 0.834 0.166
E03.3 Postinfectious hypothyroidism
0.000 0.834 0.166
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.834 0.166
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.001 0.840 0.159
E83 Disorders of mineral metabolism
0.152 0.844 0.005
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.882 0.118
E83.3 Disorders of phosphorus metabolism
0.114 0.884 0.002
E83.9 Disorder of mineral metabolism, unspecified
0.109 0.888 0.003
E83.8 Other disorders of mineral metabolism
0.109 0.888 0.003
E83.2 Disorders of zinc metabolism
0.109 0.888 0.003
E83.0 Disorders of copper metabolism
0.109 0.888 0.003
F45.8 Other somatoform disorders
0.000 0.917 0.083
K52 Other non-infective gastro-enteritis and colitis
0.080 0.919 0.001
E83.4 Disorders of magnesium metabolism
0.076 0.923 0.001
E66 Obesity
0.000 0.929 0.071
K52.0 Gastro-enteritis and colitis due to radiation
0.067 0.933 0.001
E04 Other non-toxic goitre
0.000 0.935 0.065
N84.1 Polyp of cervix uteri
0.064 0.936 0.000
E70-E90 Metabolic disorders
0.000 0.946 0.054
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.052 0.947 0.001
E73 Lactose intolerance
0.000 0.947 0.053
E73.9 Lactose intolerance, unspecified
0.000 0.948 0.052
E66.1 Drug-induced obesity
0.000 0.949 0.051
L40.9 Psoriasis, unspecified
0.000 0.949 0.051
K52.3 Indeterminate colitis
0.050 0.949 0.001
E66.0 Obesity due to excess calories
0.000 0.950 0.050
F45 Somatoform disorders
0.000 0.951 0.049
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.952 0.048
E04.8 Other specified non-toxic goitre
0.000 0.953 0.047
E74 Other disorders of carbohydrate metabolism
0.000 0.955 0.045
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.957 0.043
E84 Cystic fibrosis
0.000 0.958 0.041
E79 Disorders of purine and pyrimidine metabolism
0.000 0.959 0.041
F45.9 Somatoform disorder, unspecified
0.000 0.960 0.040
E72 Other disorders of amino-acid metabolism
0.000 0.960 0.039
E70 Disorders of aromatic amino-acid metabolism
0.000 0.961 0.039
E77 Disorders of glycoprotein metabolism
0.000 0.961 0.039
E76 Disorders of glycosaminoglycan metabolism
0.000 0.961 0.039
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.961 0.039
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.961 0.039
F45.2 Hypochondriacal disorder
0.000 0.961 0.038
E73.8 Other lactose intolerance
0.000 0.962 0.038
E73.1 Secondary lactase deficiency
0.000 0.962 0.038
E73.0 Congenital lactase deficiency
0.000 0.962 0.038
L40 Psoriasis
0.000 0.962 0.038
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.962 0.038
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.962 0.038
E88 Other metabolic disorders
0.000 0.963 0.037
F45.0 Somatisation disorder
0.000 0.963 0.037
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.963 0.037
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.963 0.036
F45.4 Persistent somatoform pain disorder
0.000 0.963 0.036
L40.5 Arthropathic psoriasis
0.000 0.964 0.036
E66.8 Other obesity
0.000 0.964 0.036
F45.1 Undifferentiated somatoform disorder
0.000 0.965 0.035
E85 Amyloidosis
0.000 0.965 0.035
E75.5 Other lipid storage disorders
0.000 0.965 0.035
E74.0 Glycogen storage disease
0.000 0.965 0.034
E04.0 Non-toxic diffuse goitre
0.000 0.966 0.034
K52.1 Toxic gastro-enteritis and colitis
0.032 0.967 0.001
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.967 0.033
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.967 0.033
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.967 0.033
E74.2 Disorders of galactose metabolism
0.000 0.967 0.033
E74.1 Disorders of fructose metabolism
0.000 0.967 0.033
E04.9 Non-toxic goitre, unspecified
0.000 0.967 0.033
E84.9 Cystic fibrosis, unspecified
0.000 0.968 0.032
L43.9 Lichen planus, unspecified
0.000 0.968 0.032
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.968 0.031
E75.6 Lipid storage disorder, unspecified
0.000 0.969 0.031
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.969 0.031
E75.3 Sphingolipidosis, unspecified
0.000 0.969 0.031
E75.2 Other sphingolipidosis
0.000 0.969 0.031
E75.1 Other gangliosidosis
0.000 0.969 0.031
E75.0 GM2 gangliosidosis
0.000 0.969 0.031
E83.5 Disorders of calcium metabolism
0.030 0.969 0.001
L43 Lichen planus
0.000 0.969 0.031
R31 Unspecified haematuria
0.031 0.969 0.000
F45.3 Somatoform autonomic dysfunction
0.000 0.970 0.030
L40-L45 Papulosquamous disorders
0.000 0.970 0.030
E84.8 Cystic fibrosis with other manifestations
0.000 0.970 0.030
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.970 0.030
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.970 0.030
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.970 0.029
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.970 0.029
E79.1 Lesch-Nyhan syndrome
0.000 0.970 0.029
E85.4 Organ-limited amyloidosis
0.000 0.970 0.030
L40.1 Generalised pustular psoriasis
0.000 0.971 0.029
E72.0 Disorders of amino-acid transport
0.000 0.971 0.029
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.971 0.028
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.971 0.028
E72.5 Disorders of glycine metabolism
0.000 0.971 0.028
E72.4 Disorders of ornithine metabolism
0.000 0.971 0.028
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.971 0.028
E72.2 Disorders of urea cycle metabolism
0.000 0.971 0.028
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.971 0.028
E88.2 Lipomatosis, not elsewhere classified
0.000 0.971 0.029
E70.3 Albinism
0.000 0.971 0.028
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.971 0.028
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.971 0.028
E70.2 Disorders of tyrosine metabolism
0.000 0.971 0.028
E70.1 Other hyperphenylalaninaemias
0.000 0.971 0.028
E70.0 Classical phenylketonuria
0.000 0.971 0.028
E71.3 Disorders of fatty-acid metabolism
0.000 0.972 0.028
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.972 0.028
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.972 0.028
E71.0 Maple-syrup-urine disease
0.000 0.972 0.028
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.972 0.028
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.972 0.028
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.972 0.028
E76.2 Other mucopolysaccharidoses
0.000 0.972 0.028
E76.1 Mucopolysaccharidosis, type II
0.000 0.972 0.028
E76.0 Mucopolysaccharidosis, type I
0.000 0.972 0.028
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.972 0.028
E77.8 Other disorders of glycoprotein metabolism
0.000 0.972 0.028
E77.1 Defects in glycoprotein degradation
0.000 0.972 0.028
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.972 0.028
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.972 0.028
L40.2 Acrodermatitis continua
0.000 0.972 0.027
E88.9 Metabolic disorder, unspecified
0.000 0.973 0.027
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.973 0.027
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.973 0.027
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.973 0.027
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.027 0.973 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.974 0.026
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.974 0.026
Z04.8 Examination and observation for other specified reasons
0.026 0.974 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.974 0.026
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.975 0.025
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.975 0.025
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.975 0.025
E88.8 Other specified metabolic disorders
0.000 0.975 0.025
K40 Inguinal hernia
0.025 0.975 0.000
L40.4 Guttate psoriasis
0.000 0.975 0.025
L43.8 Other lichen planus
0.000 0.975 0.025
E85.8 Other amyloidosis
0.000 0.975 0.024
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.024 0.976 0.000
E88.3 Tumour lysis syndrome
0.000 0.976 0.023
L43.3 Subacute (active) lichen planus
0.000 0.977 0.022
L43.2 Lichenoid drug reaction
0.000 0.977 0.022
L43.1 Bullous lichen planus
0.000 0.977 0.022
L43.0 Hypertrophic lichen planus
0.000 0.977 0.022
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.978 0.022
E85.3 Secondary systemic amyloidosis
0.000 0.978 0.022
L41 Parapsoriasis
0.000 0.978 0.022
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.978 0.022
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.021 0.979 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.979 0.021
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.021 0.979 0.000
L44 Other papulosquamous disorders
0.000 0.980 0.020
L40.8 Other psoriasis
0.000 0.980 0.020
K90-K93 Other diseases of the digestive system
0.002 0.980 0.018
K43.9 Ventral hernia without obstruction or gangrene
0.019 0.981 0.000
K43 Ventral hernia
0.019 0.981 0.000
E85.9 Amyloidosis, unspecified
0.000 0.982 0.018
K40.1 Bilateral inguinal hernia, with gangrene
0.018 0.982 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.018 0.982 0.000
K40-K46 Hernia
0.018 0.982 0.000
L42 Pityriasis rosea
0.000 0.983 0.017
L40.0 Psoriasis vulgaris
0.000 0.983 0.017
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.017 0.983 0.000
K41 Femoral hernia
0.016 0.984 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.984 0.016
E80.5 Crigler-Najjar syndrome
0.000 0.984 0.016
E80.3 Defects of catalase and peroxydase
0.000 0.984 0.016
E80.0 Hereditary erythropoietic porphyria
0.000 0.984 0.016
L41.9 Parapsoriasis, unspecified
0.000 0.984 0.016
L41.8 Other parapsoriasis
0.000 0.984 0.016
L41.5 Retiform parapsoriasis
0.000 0.984 0.016
L41.4 Large plaque parapsoriasis
0.000 0.984 0.016
L41.3 Small plaque parapsoriasis
0.000 0.984 0.016
L41.2 Lymphomatoid papulosis
0.000 0.984 0.016
L41.1 Pityriasis lichenoides chronica
0.000 0.984 0.016
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.984 0.016
E80.2 Other porphyria
0.000 0.985 0.015
E04.2 Non-toxic multinodular goitre
0.000 0.985 0.015
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.015 0.985 0.000
L44.9 Papulosquamous disorder, unspecified
0.000 0.985 0.015
L44.8 Other specified papulosquamous disorders
0.000 0.985 0.015
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.985 0.015
L44.3 Lichen ruber moniliformis
0.000 0.985 0.015
L44.2 Lichen striatus
0.000 0.985 0.015
L44.1 Lichen nitidus
0.000 0.985 0.015
M31.6 Other giant cell arteritis
0.000 0.986 0.014
K93 Disorders of other digestive organs in diseases classified elsewhere
0.002 0.986 0.013
E80.6 Other disorders of bilirubin metabolism
0.000 0.986 0.014
K43.7 Other and unspecified ventral hernia with gangrene
0.014 0.986 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.014 0.986 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.014 0.986 0.000
K43.4 Parastomal hernia with gangrene
0.014 0.986 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.014 0.986 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.014 0.986 0.000
K43.1 Ventral hernia with gangrene
0.014 0.986 0.000
E80.1 Porphyria cutanea tarda
0.000 0.986 0.014
L44.0 Pityriasis rubra pilaris
0.000 0.987 0.013
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.013 0.987 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.013 0.987 0.000
K41.1 Bilateral femoral hernia, with gangrene
0.012 0.988 0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.012 0.988 0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.012 0.988 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.012 0.988 0.000
N48.4 Impotence of organic origin
0.012 0.988 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.989 0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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