TreeWAS – Variant ID: rs3094575

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.004	0.996
E03.9 Hypothyroidism, unspecified	0.000	0.008	0.992
L40.9 Psoriasis, unspecified	0.961	0.039	0.000
L40 Psoriasis	0.867	0.133	0.000
L40.5 Arthropathic psoriasis	0.803	0.197	0.000
L40.0 Psoriasis vulgaris	0.756	0.244	0.000
K90 Intestinal malabsorption	0.000	0.277	0.723
M35.0 Sicca syndrome [Sjogren]	0.000	0.285	0.715
L40.1 Generalised pustular psoriasis	0.676	0.324	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.324	0.676
L40.4 Guttate psoriasis	0.667	0.333	0.000
L40.3 Pustulosis palmaris et plantaris	0.621	0.379	0.000
L40.2 Acrodermatitis continua	0.621	0.379	0.000
K90.8 Other intestinal malabsorption	0.000	0.439	0.561
L40.8 Other psoriasis	0.549	0.450	0.000
M35 Other systemic involvement of connective tissue	0.000	0.453	0.547
K90.3 Pancreatic steatorrhoea	0.000	0.482	0.518
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.482	0.518
K90.1 Tropical sprue	0.000	0.482	0.518
M35.3 Polymyalgia rheumatica	0.000	0.533	0.467
M35.2 Behcet's disease	0.000	0.575	0.425
M35.8 Other specified systemic involvement of connective tissue	0.000	0.578	0.422
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.608	0.392
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.608	0.392
M35.5 Multifocal fibrosclerosis	0.000	0.608	0.392
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.608	0.392
M35.1 Other overlap syndromes	0.000	0.613	0.387
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.617	0.382
M22.2 Patellofemoral disorders	0.000	0.672	0.328
M22 Disorders of patella	0.000	0.672	0.328
M20-M25 Other joint disorders	0.000	0.675	0.325
M34 Systemic sclerosis	0.000	0.679	0.321
M34.1 CR(E)ST syndrome	0.000	0.696	0.304
M35.7 Hypermobility syndrome	0.000	0.703	0.296
M22.3 Other derangements of patella	0.000	0.704	0.296
E03 Other hypothyroidism	0.000	0.708	0.292
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.719	0.281
M34.9 Systemic sclerosis, unspecified	0.000	0.721	0.279
M34.8 Other forms of systemic sclerosis	0.000	0.733	0.267
M30 Polyarteritis nodosa and related conditions	0.000	0.746	0.254
M22.9 Disorder of patella, unspecified	0.000	0.759	0.241
M22.1 Recurrent subluxation of patella	0.000	0.765	0.235
M22.0 Recurrent dislocation of patella	0.000	0.767	0.233
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.770	0.230
M34.0 Progressive systemic sclerosis	0.000	0.770	0.230
M32 Systemic lupus erythematosus	0.000	0.773	0.226
M33 Dermatopolymyositis	0.000	0.776	0.224
M22.8 Other disorders of patella	0.000	0.778	0.222
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.788	0.212
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.789	0.210
E03.5 Myxoedema coma	0.000	0.790	0.209
E03.4 Atrophy of thyroid (acquired)	0.000	0.790	0.209
E03.3 Postinfectious hypothyroidism	0.000	0.790	0.209
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.795	0.205
M31 Other necrotising vasculopathies	0.000	0.796	0.204
M22.4 Chondromalacia patellae	0.000	0.796	0.203
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.817	0.182
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.817	0.182
M30.2 Juvenile polyarteritis	0.000	0.817	0.182
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.818	0.182
L40-L45 Papulosquamous disorders	0.170	0.830	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.831	0.169
M30.0 Polyarteritis nodosa	0.000	0.832	0.168
M31.6 Other giant cell arteritis	0.000	0.835	0.165
E03.1 Congenital hypothyroidism without goitre	0.001	0.835	0.164
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.837	0.162
M32.8 Other forms of systemic lupus erythematosus	0.000	0.837	0.162
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.837	0.162
M33.9 Dermatopolymyositis, unspecified	0.000	0.839	0.161
M33.0 Juvenile dermatomyositis	0.000	0.839	0.161
M33.1 Other dermatomyositis	0.000	0.840	0.160
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.844	0.155
E03.8 Other specified hypothyroidism	0.000	0.846	0.153
E00-E07 Disorders of thyroid gland	0.000	0.847	0.153
M33.2 Polymyositis	0.000	0.847	0.152
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.849	0.151
M36.3 Arthropathy in other blood disorders	0.000	0.849	0.151
M36.2 Haemophilic arthropathy	0.000	0.849	0.151
M36.1 Arthropathy in neoplastic disease	0.000	0.849	0.151
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.849	0.151
M31.9 Necrotising vasculopathy, unspecified	0.000	0.853	0.147
M31.8 Other specified necrotising vasculopathies	0.000	0.853	0.146
M31.7 Microscopic polyangiitis	0.000	0.853	0.146
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.853	0.146
M31.2 Lethal midline granuloma	0.000	0.853	0.146
M31.1 Thrombotic microangiopathy	0.000	0.853	0.146
E06 Thyroiditis	0.000	0.856	0.144
M47.82 Other spondylosis (Cervical region)	0.142	0.858	0.000
E06.3 Autoimmune thyroiditis	0.000	0.861	0.139
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.864	0.136
I63.9 Cerebral infarction, unspecified	0.000	0.865	0.135
I63 Cerebral infarction	0.000	0.867	0.133
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.867	0.133
E07 Other disorders of thyroid	0.000	0.871	0.129
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.872	0.128
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.872	0.128
M31.3 Wegener's granulomatosis	0.000	0.872	0.128
M24 Other specific joint derangements	0.000	0.875	0.125
M31.0 Hypersensitivity angiitis	0.000	0.877	0.123
L44 Other papulosquamous disorders	0.122	0.878	0.000
L41 Parapsoriasis	0.122	0.878	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.122	0.878	0.000
M21 Other acquired deformities of limbs	0.001	0.881	0.118
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.883	0.117
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.888	0.112
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.890	0.110
E00 Congenital iodine-deficiency syndrome	0.000	0.890	0.110
E07.9 Disorder of thyroid, unspecified	0.000	0.891	0.109
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.895	0.105
L42 Pityriasis rosea	0.104	0.896	0.000
E06.5 Other chronic thyroiditis	0.000	0.897	0.103
E06.4 Drug-induced thyroiditis	0.000	0.897	0.103
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.897	0.103
E06.1 Subacute thyroiditis	0.000	0.897	0.103
E06.0 Acute thyroiditis	0.000	0.897	0.103
E06.9 Thyroiditis, unspecified	0.000	0.901	0.099
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.901	0.099
M21.6 Other acquired deformities of ankle and foot	0.000	0.901	0.099
M24.6 Ankylosis of joint	0.000	0.901	0.099
E07.8 Other specified disorders of thyroid	0.000	0.903	0.097
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.903	0.097
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.904	0.096
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.904	0.096
M21.7 Unequal limb length (acquired)	0.000	0.906	0.094
E07.1 Dyshormogenetic goitre	0.000	0.907	0.092
E07.0 Hypersecretion of calcitonin	0.000	0.907	0.092
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.908	0.092
M21.0 Valgus deformity, not elsewhere classified	0.000	0.908	0.091
M24.9 Joint derangement, unspecified	0.000	0.910	0.090
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.911	0.089
L41.9 Parapsoriasis, unspecified	0.087	0.912	0.000
L41.8 Other parapsoriasis	0.087	0.912	0.000
L41.5 Retiform parapsoriasis	0.087	0.912	0.000
L41.4 Large plaque parapsoriasis	0.087	0.912	0.000
L41.3 Small plaque parapsoriasis	0.087	0.912	0.000
L41.2 Lymphomatoid papulosis	0.087	0.912	0.000
L41.1 Pityriasis lichenoides chronica	0.087	0.912	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.087	0.912	0.000
L44.9 Papulosquamous disorder, unspecified	0.087	0.912	0.000
L44.8 Other specified papulosquamous disorders	0.087	0.912	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.087	0.912	0.000
L44.3 Lichen ruber moniliformis	0.087	0.912	0.000
L44.2 Lichen striatus	0.087	0.912	0.000
L44.1 Lichen nitidus	0.087	0.912	0.000
L44.0 Pityriasis rubra pilaris	0.087	0.912	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.915	0.085
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.915	0.085
M21.8 Other specified acquired deformities of limbs	0.001	0.915	0.084
M24.7 Protrusio acetabuli	0.000	0.916	0.084
M47.8 Other spondylosis	0.084	0.916	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.916	0.083
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.919	0.081
M21.4 Flat foot [pes planus] (acquired)	0.001	0.920	0.079
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.000	0.921	0.079
M21.9 Acquired deformity of limb, unspecified	0.001	0.921	0.079
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.921	0.079
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.000	0.921	0.079
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.921	0.079
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.921	0.079
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.921	0.079
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.921	0.079
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.921	0.079
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.921	0.079
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.921	0.079
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.921	0.079
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.001	0.921	0.078
I63.8 Other cerebral infarction	0.000	0.921	0.079
M24.2 Disorder of ligament	0.000	0.922	0.078
K90-K93 Other diseases of the digestive system	0.000	0.922	0.078
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.922	0.078
E83.1 Disorders of iron metabolism	0.000	0.924	0.076
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.924	0.076
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.924	0.075
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.925	0.075
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.925	0.075
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.925	0.075
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.926	0.074
M23 Internal derangement of knee	0.000	0.927	0.073
M47.80 Other spondylosis (Multiple sites in spine)	0.072	0.928	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.928	0.072
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.929	0.071
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.929	0.071
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.929	0.071
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.929	0.071
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.929	0.071
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.929	0.071
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.929	0.071
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.929	0.071
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.929	0.071
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.929	0.071
M24.68 Ankylosis of joint (Other)	0.000	0.929	0.071
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.929	0.071
M24.64 Ankylosis of joint (Hand)	0.000	0.929	0.071
M24.63 Ankylosis of joint (Forearm)	0.000	0.929	0.071
M24.62 Ankylosis of joint (Upper arm)	0.000	0.929	0.071
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.929	0.071
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.929	0.071
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.929	0.071
M24.66 Ankylosis of joint (Lower leg)	0.000	0.931	0.069
M47.89 Other spondylosis (Site unspecified)	0.069	0.931	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.931	0.069
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.932	0.067
M21.78 Unequal limb length (acquired)-Other	0.000	0.932	0.067
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.932	0.067
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.932	0.067
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.932	0.067
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.932	0.067
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.932	0.067
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.932	0.067
M47.83 Other spondylosis (Cervicothoracic region)	0.067	0.933	0.000
L43 Lichen planus	0.067	0.933	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.000	0.934	0.066
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.000	0.934	0.066
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.000	0.934	0.066
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.934	0.066
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.000	0.934	0.066
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.000	0.934	0.066
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.000	0.934	0.066
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.000	0.934	0.066
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.000	0.934	0.066
M24.1 Other articular cartilage disorders	0.000	0.934	0.066
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.934	0.066
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.934	0.066
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.934	0.066
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.934	0.066
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.934	0.066
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.934	0.066
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.934	0.066
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.934	0.066
M23.4 Loose body in knee	0.000	0.934	0.066
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.065	0.935	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.935	0.064
M24.98 Joint derangement, unspecified (Other)	0.000	0.935	0.064
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.935	0.064
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.935	0.064
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.935	0.064
M24.94 Joint derangement, unspecified (Hand)	0.000	0.935	0.064
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.935	0.064
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.935	0.064
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.935	0.064
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.935	0.064
M47.85 Other spondylosis (Thoracolumbar region)	0.064	0.936	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.939	0.061
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.939	0.061
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.939	0.061
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.939	0.061
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.939	0.061
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.939	0.061
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.001	0.939	0.061
M21.88 Other specified acquired deformities of limbs-Other	0.001	0.939	0.061
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.001	0.939	0.061
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.001	0.939	0.061
M21.84 Other specified acquired deformities of limbs (Hand)	0.001	0.939	0.061
M21.83 Other specified acquired deformities of limbs (Forearm)	0.001	0.939	0.061
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.001	0.939	0.061
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.001	0.939	0.061
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.001	0.939	0.061
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.001	0.939	0.060
M24.79 Protrusio acetabuli-Site unspec	0.000	0.940	0.060
M24.78 Protrusio acetabuli-Other	0.000	0.940	0.060
M24.77 Protrusio acetabuli-Ankle/foot	0.000	0.940	0.060
M24.76 Protrusio acetabuli-Lower leg	0.000	0.940	0.060
M24.74 Protrusio acetabuli-Hand	0.000	0.940	0.060
M24.73 Protrusio acetabuli-Forearm	0.000	0.940	0.060
M24.72 Protrusio acetabuli-Upper arm	0.000	0.940	0.060
M24.71 Protrusio acetabuli-Shldr region	0.000	0.940	0.060
M24.70 Protrusio acetabuli-Mult sites	0.000	0.940	0.060
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.060	0.940	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.940	0.060
M24.0 Loose body in joint	0.000	0.940	0.059
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.941	0.059
M24.26 Disorder of ligament (Lower leg)	0.000	0.941	0.059
M24.21 Disorder of ligament (Shoulder region)	0.000	0.941	0.059
M23.49 Loose body in knee-Unspec lig/men	0.000	0.941	0.059
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.941	0.059
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.001	0.943	0.057
M21.48 Flat foot [pes planus] (acquired)-Other	0.001	0.943	0.057
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.001	0.943	0.057
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.001	0.943	0.057
M21.44 Flat foot [pes planus] (acquired)-Hand	0.001	0.943	0.057
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.001	0.943	0.057
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.001	0.943	0.057
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.001	0.943	0.057
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.001	0.943	0.057
M24.5 Contracture of joint	0.000	0.943	0.057
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.001	0.943	0.057
M21.98 Acquired deformity of limb, unspecified-Other	0.001	0.943	0.057
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.001	0.943	0.057
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.001	0.943	0.057
M21.94 Acquired deformity of limb, unspecified (Hand)	0.001	0.943	0.057
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.001	0.943	0.057
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.001	0.943	0.057
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.001	0.943	0.057
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.001	0.943	0.057
M23.9 Internal derangement of knee, unspecified	0.000	0.943	0.057
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.001	0.943	0.056
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.001	0.943	0.056
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.001	0.943	0.056
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.001	0.943	0.056
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.001	0.943	0.056
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.001	0.943	0.056
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.001	0.943	0.056
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.001	0.943	0.056
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.001	0.943	0.056
M24.29 Disorder of ligament (Site unspecified)	0.000	0.943	0.056
M24.28 Disorder of ligament (Other)	0.000	0.943	0.056
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.943	0.056
M24.22 Disorder of ligament (Upper arm)	0.000	0.943	0.056
M24.20 Disorder of ligament (Multiple sites)	0.000	0.943	0.056
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.944	0.056
M21.3 Wrist or foot drop (acquired)	0.003	0.945	0.053
M24.75 Protrusio acetabuli-Pelvic/thigh	0.000	0.945	0.054
M21.2 Flexion deformity	0.001	0.946	0.054
M47.84 Other spondylosis (Thoracic region)	0.053	0.947	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.947	0.052
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.947	0.053
M47.87 Other spondylosis (Lumbosacral region)	0.052	0.948	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.948	0.052
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.001	0.948	0.051
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.949	0.051
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.001	0.949	0.051
M24.24 Disorder of ligament (Hand)	0.000	0.949	0.051
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.001	0.949	0.050
M23.46 Loose body in knee-O/unsp lat men	0.000	0.950	0.050
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.950	0.050
M23.5 Chronic instability of knee	0.000	0.950	0.050
M24.23 Disorder of ligament (Forearm)	0.000	0.950	0.050
M23.43 Loose body in knee-Med lig/oth men	0.000	0.950	0.049
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.000	0.951	0.049
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.951	0.049
M21.1 Varus deformity, not elsewhere classified	0.001	0.951	0.048
M23.1 Discoid meniscus (congenital)	0.000	0.951	0.049
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.952	0.048
L43.3 Subacute (active) lichen planus	0.048	0.952	0.000
L43.2 Lichenoid drug reaction	0.048	0.952	0.000
L43.1 Bullous lichen planus	0.048	0.952	0.000
L43.0 Hypertrophic lichen planus	0.048	0.952	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.952	0.048
M24.18 Other articular cartilage disorders (Other)	0.000	0.952	0.048
M24.14 Other articular cartilage disorders (Hand)	0.000	0.952	0.048
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.952	0.048
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.952	0.048
M23.0 Cystic meniscus	0.000	0.952	0.048
M23.47 Loose body in knee-Capsular lig	0.000	0.952	0.047
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.952	0.047
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.952	0.047
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.952	0.047
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.952	0.047
M23.40 Loose body in knee-Mult sites	0.000	0.952	0.047
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.953	0.047
M24.09 Loose body in joint (Site unspecified)	0.000	0.957	0.043
M24.08 Loose body in joint (Other)	0.000	0.957	0.043
M24.06 Loose body in joint-Lower leg	0.000	0.957	0.043
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.957	0.043
M24.00 Loose body in joint (Multiple sites)	0.000	0.957	0.043
E83 Disorders of mineral metabolism	0.000	0.957	0.043
M24.02 Loose body in joint (Upper arm)	0.000	0.958	0.042
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.958	0.042
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.958	0.042
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.958	0.042
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.958	0.042
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.958	0.042
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.958	0.042
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.958	0.042
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.958	0.042
M24.59 Contracture of joint (Site unspecified)	0.000	0.959	0.041
M24.58 Contracture of joint (Other)	0.000	0.959	0.041
M24.53 Contracture of joint (Forearm)	0.000	0.959	0.041
M24.52 Contracture of joint (Upper arm)	0.000	0.959	0.041
M24.50 Contracture of joint (Multiple sites)	0.000	0.959	0.041
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.959	0.041
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.959	0.041
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.959	0.041
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.959	0.041
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.959	0.041
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.959	0.041
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.959	0.041
M24.04 Loose body in joint (Hand)	0.000	0.959	0.041
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.959	0.041
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.959	0.040
K93.1 Megacolon in Chagas' disease	0.000	0.959	0.040
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.959	0.040
E04 Other non-toxic goitre	0.000	0.960	0.040
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.960	0.038
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.960	0.038
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.960	0.038
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.960	0.038
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.960	0.038
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.960	0.038
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.960	0.038
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.960	0.038
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.960	0.038
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.960	0.039
M24.57 Contracture of joint (Ankle and foot)	0.000	0.960	0.039
M21.29 Flexion deformity (Site unspecified)	0.001	0.961	0.039
M21.28 Flexion deformity (Other)	0.001	0.961	0.039
M21.25 Flexion deformity (Pelvic region and thigh)	0.001	0.961	0.039
M21.23 Flexion deformity (Forearm)	0.001	0.961	0.039
M21.22 Flexion deformity (Upper arm)	0.001	0.961	0.039
M21.21 Flexion deformity (Shoulder region)	0.001	0.961	0.039
M21.20 Flexion deformity (Multiple sites)	0.001	0.961	0.039
M24.03 Loose body in joint (Forearm)	0.000	0.961	0.039
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.961	0.039
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.962	0.038
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.962	0.038
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.962	0.038
E05.5 Thyroid crisis or storm	0.000	0.962	0.038
E05.4 Thyrotoxicosis factitia	0.000	0.962	0.038
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.962	0.038
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.962	0.038
M24.51 Contracture of joint (Shoulder region)	0.000	0.962	0.037
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.962	0.038
M24.56 Contracture of joint (Lower leg)	0.000	0.962	0.037
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.964	0.036
M24.07 Loose body in joint (Ankle and foot)	0.000	0.964	0.036
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.964	0.036
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.964	0.036
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.964	0.036
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.964	0.036
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.964	0.036
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.964	0.036
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.964	0.036
M24.01 Loose body in joint (Shoulder region)	0.000	0.964	0.036
M21.24 Flexion deformity (Hand)	0.001	0.964	0.035
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.001	0.964	0.035
M21.18 Varus deformity, not elsewhere classified (Other)	0.001	0.964	0.035
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.001	0.964	0.035
M21.14 Varus deformity, not elsewhere classified (Hand)	0.001	0.964	0.035
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.001	0.964	0.035
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.001	0.964	0.035
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.001	0.964	0.035
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.001	0.964	0.035
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.964	0.035
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.964	0.035
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.964	0.035
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.964	0.035
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.964	0.035
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.964	0.035
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.964	0.035
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.964	0.035
E83.3 Disorders of phosphorus metabolism	0.000	0.965	0.035
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.965	0.035
M23.07 Cystic meniscus-Capsular lig	0.000	0.965	0.034
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.965	0.034
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.965	0.034
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.965	0.034
M23.00 Cystic meniscus (Multiple sites)	0.000	0.965	0.034
L43.8 Other lichen planus	0.033	0.967	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.967	0.033
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.968	0.032
M47.86 Other spondylosis (Lumbar region)	0.031	0.969	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.969	0.031
E83.8 Other disorders of mineral metabolism	0.000	0.969	0.031
E83.2 Disorders of zinc metabolism	0.000	0.969	0.031
E83.0 Disorders of copper metabolism	0.000	0.969	0.031
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.000	0.969	0.031
M21.26 Flexion deformity (Lower leg)	0.001	0.969	0.030
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.970	0.030
K91.4 Colostomy and enterostomy malfunction	0.000	0.970	0.030
M21.27 Flexion deformity (Ankle and foot)	0.001	0.970	0.029
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.970	0.030
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.970	0.029
E04.0 Non-toxic diffuse goitre	0.000	0.970	0.029
M24.54 Contracture of joint (Hand)	0.000	0.971	0.029
K91.5 Postcholecystectomy syndrome	0.000	0.971	0.029
E04.8 Other specified non-toxic goitre	0.000	0.971	0.029
E05.9 Thyrotoxicosis, unspecified	0.000	0.971	0.029
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.971	0.029
E04.2 Non-toxic multinodular goitre	0.000	0.971	0.029
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.972	0.028
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.001	0.974	0.025
L43.9 Lichen planus, unspecified	0.026	0.974	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.975	0.025
R06.5 Mouth breathing	0.024	0.976	0.000
K91.1 Postgastric surgery syndromes	0.000	0.976	0.024
E05.8 Other thyrotoxicosis	0.000	0.976	0.024
E83.5 Disorders of calcium metabolism	0.000	0.976	0.024
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.976	0.024
K91.3 Postoperative intestinal obstruction	0.000	0.978	0.022
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.001	0.980	0.019
E16.2 Hypoglycaemia, unspecified	0.020	0.980	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.982	0.018
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.983	0.017
M23.8 Other internal derangements of knee	0.000	0.983	0.016
M23.3 Other meniscus derangements	0.000	0.983	0.017
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.984	0.016
M89.9 Disorder of bone, unspecified	0.016	0.984	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.985	0.015
M89 Other disorders of bone	0.015	0.985	0.000
M89.0 Algoneurodystrophy	0.015	0.985	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.015	0.985	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.015	0.985	0.000
E50-E64 Other nutritional deficiencies	0.000	0.985	0.015
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.986	0.014
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.986	0.014
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.986	0.014
H90.0 Conductive hearing loss, bilateral	0.000	0.987	0.013
E16 Other disorders of pancreatic internal secretion	0.010	0.987	0.003
M89.03 Algoneurodystrophy (Forearm)	0.013	0.987	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.987	0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations