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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094577
log Bayes Factor = 37.9185
Chromosome 6   position 29,533,870  (GRCh37) Explore rs3094577 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.016 0.984
E16.2 Hypoglycaemia, unspecified
0.000 0.016 0.984
E16 Other disorders of pancreatic internal secretion
0.000 0.016 0.984
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.017 0.983
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.017 0.983
E10.4 With neurological complications
0.000 0.026 0.974
E20-E35 Disorders of other endocrine glands
0.000 0.032 0.968
E23 Hypofunction and other disorders of pituitary gland
0.000 0.044 0.956
E13 Other specified diabetes mellitus
0.000 0.051 0.949
E10.2 With renal complications
0.000 0.054 0.946
E23.0 Hypopituitarism
0.000 0.063 0.937
E13.9 Without complications
0.000 0.084 0.916
E10.6 With other specified complications
0.000 0.090 0.910
E16.1 Other hypoglycaemia
0.000 0.114 0.886
K51.9 Ulcerative colitis, unspecified
0.870 0.130 0.000
E24 Cushing's syndrome
0.000 0.131 0.869
K51 Ulcerative colitis
0.869 0.131 0.000
K51.4 Pseudopolyposis of colon
0.844 0.156 0.000
E10.0 With coma
0.000 0.162 0.838
E23.7 Disorder of pituitary gland, unspecified
0.000 0.180 0.820
E10.5 With peripheral circulatory complications
0.000 0.197 0.803
K51.8 Other ulcerative colitis
0.793 0.207 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.230 0.770
E23.2 Diabetes insipidus
0.000 0.243 0.757
E25 Adrenogenital disorders
0.000 0.263 0.737
E29 Testicular dysfunction
0.000 0.271 0.729
E28 Ovarian dysfunction
0.000 0.278 0.722
E10.7 With multiple complications
0.000 0.283 0.717
E27 Other disorders of adrenal gland
0.000 0.284 0.716
K51.2 Ulcerative (chronic) proctitis
0.716 0.284 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.287 0.713
E24.2 Drug-induced Cushing's syndrome
0.000 0.290 0.710
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.294 0.706
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.294 0.706
E16.4 Abnormal secretion of gastrin
0.000 0.294 0.706
E16.3 Increased secretion of glucagon
0.000 0.294 0.706
E15 Nondiabetic hypoglycaemic coma
0.000 0.295 0.705
E20 Hypoparathyroidism
0.000 0.298 0.702
E22 Hyperfunction of pituitary gland
0.000 0.302 0.698
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.306 0.694
E32 Diseases of thymus
0.000 0.306 0.694
E30 Disorders of puberty, not elsewhere classified
0.000 0.306 0.694
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.314 0.686
E23.1 Drug-induced hypopituitarism
0.000 0.314 0.686
K50-K52 Noninfective enteritis and colitis
0.685 0.315 0.000
E13.8 With unspecified complications
0.000 0.320 0.680
E13.7 With multiple complications
0.000 0.320 0.680
E13.6 With other specified complications
0.000 0.320 0.680
E13.5 With peripheral circulatory complications
0.000 0.320 0.680
E13.4 With neurological complications
0.000 0.320 0.680
E13.3 With ophthalmic complications
0.000 0.320 0.680
E13.2 With renal complications
0.000 0.320 0.680
E13.1 With ketoacidosis
0.000 0.320 0.680
E13.0 With coma
0.000 0.320 0.680
E14 Unspecified diabetes mellitus
0.000 0.323 0.677
K50 Crohn's disease [regional enteritis]
0.675 0.325 0.000
K50.9 Crohn's disease, unspecified
0.666 0.334 0.000
E31 Polyglandular dysfunction
0.000 0.346 0.654
E23.6 Other disorders of pituitary gland
0.000 0.349 0.651
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.372 0.628
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.377 0.623
E24.3 Ectopic ACTH syndrome
0.000 0.377 0.623
E24.1 Nelson's syndrome
0.000 0.377 0.623
E24.0 Pituitary-dependent Cushing's disease
0.000 0.377 0.623
K51.5 Mucosal proctocolitis
0.616 0.384 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.616 0.384 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.611 0.389 0.000
E24.8 Other Cushing's syndrome
0.000 0.400 0.600
E40-E46 Malnutrition
0.000 0.406 0.594
E27.1 Primary adrenocortical insufficiency
0.000 0.407 0.593
K50.1 Crohn's disease of large intestine
0.586 0.414 0.000
E10.8 With unspecified complications
0.000 0.415 0.585
E34 Other endocrine disorders
0.000 0.419 0.581
E14.3 With ophthalmic complications
0.000 0.423 0.577
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.428 0.572
E27.8 Other specified disorders of adrenal gland
0.000 0.437 0.563
E28.3 Primary ovarian failure
0.000 0.439 0.561
E29.1 Testicular hypofunction
0.000 0.442 0.558
E22.0 Acromegaly and pituitary gigantism
0.000 0.445 0.555
E26 Hyperaldosteronism
0.000 0.445 0.555
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.467 0.533
E25.9 Adrenogenital disorder, unspecified
0.000 0.471 0.529
E25.8 Other adrenogenital disorders
0.000 0.471 0.529
E29.9 Testicular dysfunction, unspecified
0.000 0.477 0.523
E29.8 Other testicular dysfunction
0.000 0.477 0.523
E29.0 Testicular hyperfunction
0.000 0.477 0.523
E28.9 Ovarian dysfunction, unspecified
0.000 0.482 0.518
E28.8 Other ovarian dysfunction
0.000 0.482 0.518
E28.1 Androgen excess
0.000 0.482 0.518
E28.0 Oestrogen excess
0.000 0.482 0.518
E14.4 With neurological complications
0.000 0.485 0.515
E27.5 Adrenomedullary hyperfunction
0.000 0.486 0.514
E27.0 Other adrenocortical overactivity
0.000 0.486 0.514
E20.9 Hypoparathyroidism, unspecified
0.000 0.488 0.512
K90 Intestinal malabsorption
0.000 0.488 0.512
E12.9 Without complications
0.000 0.488 0.511
E12.8 With unspecified complications
0.000 0.488 0.511
E12.7 With multiple complications
0.000 0.488 0.511
E12.6 With other specified complications
0.000 0.488 0.511
E12.5 With peripheral circulatory complications
0.000 0.488 0.511
E12.4 With neurological complications
0.000 0.488 0.511
E12.3 With ophthalmic complications
0.000 0.488 0.511
E12.2 With renal complications
0.000 0.488 0.511
E12.1 With ketoacidosis
0.000 0.488 0.511
E12.0 With coma
0.000 0.488 0.511
E11 Non-insulin-dependent diabetes mellitus
0.000 0.491 0.509
E14.6 With other specified complications
0.000 0.493 0.507
E20.8 Other hypoparathyroidism
0.000 0.496 0.503
E20.1 Pseudohypoparathyroidism
0.000 0.496 0.503
E20.0 Idiopathic hypoparathyroidism
0.000 0.496 0.503
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.500 0.500
E22.8 Other hyperfunction of pituitary gland
0.000 0.500 0.500
E14.1 With ketoacidosis
0.000 0.500 0.500
E22.1 Hyperprolactinaemia
0.000 0.500 0.500
E28.2 Polycystic ovarian syndrome
0.000 0.501 0.499
E30.9 Disorder of puberty, unspecified
0.000 0.502 0.497
E30.8 Other disorders of puberty
0.000 0.502 0.497
E30.1 Precocious puberty
0.000 0.502 0.497
E30.0 Delayed puberty
0.000 0.502 0.497
E32.9 Disease of thymus, unspecified
0.000 0.502 0.497
E32.8 Other diseases of thymus
0.000 0.502 0.497
E32.1 Abscess of thymus
0.000 0.502 0.497
E32.0 Persistent hyperplasia of thymus
0.000 0.502 0.497
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.502 0.497
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.502 0.497
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.502 0.497
K50.0 Crohn's disease of small intestine
0.487 0.513 0.000
E14.7 With multiple complications
0.000 0.515 0.485
E14.5 With peripheral circulatory complications
0.000 0.515 0.485
E14.0 With coma
0.000 0.515 0.485
E00-E07 Disorders of thyroid gland
0.000 0.521 0.479
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.525 0.475
E31.9 Polyglandular dysfunction, unspecified
0.000 0.531 0.469
E31.8 Other polyglandular dysfunction
0.000 0.531 0.469
E31.1 Polyglandular hyperfunction
0.000 0.531 0.469
E27.9 Disorder of adrenal gland, unspecified
0.000 0.533 0.467
E14.2 Withrenal complications
0.000 0.534 0.466
E11.2 With renal complications
0.000 0.538 0.462
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.540 0.460
E34.8 Other specified endocrine disorders
0.000 0.548 0.452
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.556 0.444
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.560 0.440
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.569 0.431
E31.0 Autoimmune polyglandular failure
0.000 0.570 0.430
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.574 0.426
E45 Retarded development following protein-energy malnutrition
0.000 0.574 0.426
E43 Unspecified severe protein-energy malnutrition
0.000 0.574 0.426
E42 Marasmic kwashiorkor
0.000 0.574 0.426
E41 Nutritional marasmus
0.000 0.574 0.426
E40 Kwashiorkor
0.000 0.574 0.426
E11.1 With ketoacidosis
0.000 0.575 0.425
E27.2 Addisonian crisis
0.000 0.579 0.421
E34.3 Short stature, not elsewhere classified
0.000 0.580 0.419
E34.5 Androgen resistance syndrome
0.000 0.583 0.416
E34.4 Constitutional tall stature
0.000 0.583 0.416
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.583 0.416
E34.1 Other hypersecretion of intestinal hormones
0.000 0.583 0.416
E50-E64 Other nutritional deficiencies
0.000 0.587 0.413
E14.8 With unspecified complications
0.000 0.588 0.412
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.596 0.403
E26.9 Hyperaldosteronism, unspecified
0.000 0.599 0.400
E11.0 With coma
0.000 0.602 0.398
E26.8 Other hyperaldosteronism
0.000 0.602 0.398
E26.1 Secondary hyperaldosteronism
0.000 0.602 0.398
E11.6 With other specified complications
0.000 0.607 0.393
E05.8 Other thyrotoxicosis
0.000 0.611 0.389
E11.8 With unspecified complications
0.000 0.617 0.383
K90.9 Intestinal malabsorption, unspecified
0.000 0.621 0.379
K90.3 Pancreatic steatorrhoea
0.000 0.633 0.367
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.633 0.367
K90.1 Tropical sprue
0.000 0.633 0.367
E11.7 With multiple complications
0.000 0.635 0.365
E05.9 Thyrotoxicosis, unspecified
0.000 0.637 0.363
K90.8 Other intestinal malabsorption
0.000 0.642 0.358
E21.3 Hyperparathyroidism, unspecified
0.000 0.652 0.348
E34.9 Endocrine disorder, unspecified
0.000 0.656 0.343
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.657 0.343
E00 Congenital iodine-deficiency syndrome
0.000 0.657 0.343
K50.8 Other Crohn's disease
0.342 0.657 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.667 0.333
E34.0 Carcinoid syndrome
0.000 0.668 0.332
E05.5 Thyroid crisis or storm
0.000 0.670 0.330
E05.4 Thyrotoxicosis factitia
0.000 0.670 0.330
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.670 0.330
E83 Disorders of mineral metabolism
0.327 0.673 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.676 0.324
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.678 0.322
E11.5 With peripheral circulatory complications
0.000 0.681 0.319
E21.4 Other specified disorders of parathyroid gland
0.000 0.682 0.318
E46 Unspecified protein-energy malnutrition
0.000 0.685 0.315
E07 Other disorders of thyroid
0.000 0.687 0.313
E21.2 Other hyperparathyroidism
0.000 0.692 0.308
E44.1 Mild protein-energy malnutrition
0.000 0.694 0.305
E44.0 Moderate protein-energy malnutrition
0.000 0.694 0.305
E61 Deficiency of other nutrient elements
0.000 0.696 0.304
E51 Thiamine deficiency
0.000 0.704 0.296
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.704 0.296
E63 Other nutritional deficiencies
0.000 0.704 0.296
E50 Vitamin A deficiency
0.000 0.704 0.296
E60 Dietary zinc deficiency
0.000 0.704 0.296
E59 Dietary selenium deficiency
0.000 0.704 0.296
E54 Ascorbic acid deficiency
0.000 0.704 0.296
E52 Niacin deficiency [pellagra]
0.000 0.704 0.296
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.705 0.295
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.706 0.294
E56 Other vitamin deficiencies
0.000 0.713 0.287
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.718 0.282
E14.9 Without complications
0.000 0.737 0.263
E58 Dietary calcium deficiency
0.000 0.738 0.262
E83.4 Disorders of magnesium metabolism
0.257 0.743 0.000
E07.8 Other specified disorders of thyroid
0.000 0.745 0.255
E26.0 Primary hyperaldosteronism
0.001 0.746 0.254
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.754 0.246
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.754 0.246
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.754 0.246
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.754 0.246
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.754 0.246
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.754 0.246
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.754 0.246
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.754 0.246
E83.3 Disorders of phosphorus metabolism
0.241 0.759 0.000
E61.1 Iron deficiency
0.000 0.763 0.237
E83.9 Disorder of mineral metabolism, unspecified
0.235 0.765 0.000
E83.8 Other disorders of mineral metabolism
0.235 0.765 0.000
E83.2 Disorders of zinc metabolism
0.235 0.765 0.000
E83.0 Disorders of copper metabolism
0.235 0.765 0.000
E67 Other hyperalimentation
0.000 0.767 0.232
E68 Sequelae of hyperalimentation
0.000 0.767 0.232
E53 Deficiency of other B group vitamins
0.000 0.769 0.231
E03 Other hypothyroidism
0.000 0.775 0.225
E07.1 Dyshormogenetic goitre
0.000 0.776 0.224
E07.0 Hypersecretion of calcitonin
0.000 0.776 0.224
E61.9 Deficiency of nutrient element, unspecified
0.000 0.782 0.218
E61.8 Deficiency of other specified nutrient elements
0.000 0.782 0.218
E61.7 Deficiency of multiple nutrient elements
0.000 0.782 0.218
E61.6 Vanadium deficiency
0.000 0.782 0.218
E61.5 Molybdenum deficiency
0.000 0.782 0.218
E61.4 Chromium deficiency
0.000 0.782 0.218
E61.3 Manganese deficiency
0.000 0.782 0.218
E61.0 Copper deficiency
0.000 0.782 0.218
E51.2 Wernicke's encephalopathy
0.000 0.787 0.213
E51.9 Thiamine deficiency, unspecified
0.000 0.787 0.213
E51.8 Other manifestations of thiamine deficiency
0.000 0.787 0.213
E51.1 Beriberi
0.000 0.787 0.213
E50.9 Vitamin A deficiency, unspecified
0.000 0.787 0.212
E50.8 Other manifestations of vitamin A deficiency
0.000 0.787 0.212
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.787 0.212
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.787 0.212
E50.5 Vitamin A deficiency with night blindness
0.000 0.787 0.212
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.787 0.212
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.787 0.212
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.787 0.212
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.787 0.212
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.787 0.212
E63.9 Nutritional deficiency, unspecified
0.000 0.787 0.212
E63.8 Other specified nutritional deficiencies
0.000 0.787 0.212
E63.1 Imbalance of constituents of food intake
0.000 0.787 0.212
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.787 0.212
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.787 0.212
E64.8 Sequelae of other nutritional deficiencies
0.000 0.787 0.212
E64.3 Sequelae of rickets
0.000 0.787 0.212
E64.2 Sequelae of vitamin C deficiency
0.000 0.787 0.212
E64.1 Sequelae of vitamin A deficiency
0.000 0.787 0.212
E64.0 Sequelae of protein-energy malnutrition
0.000 0.787 0.212
E55 Vitamin D deficiency
0.000 0.789 0.211
E56.9 Vitamin deficiency, unspecified
0.000 0.794 0.206
E56.8 Deficiency of other vitamins
0.000 0.794 0.206
E56.0 Deficiency of vitamin E
0.000 0.794 0.206
E61.2 Magnesium deficiency
0.000 0.795 0.204
E56.1 Deficiency of vitamin K
0.000 0.803 0.197
E11.4 With neurological complications
0.000 0.818 0.182
E03.8 Other specified hypothyroidism
0.000 0.818 0.182
E03.1 Congenital hypothyroidism without goitre
0.000 0.821 0.179
E67.8 Other specified hyperalimentation
0.000 0.833 0.167
E67.3 Hypervitaminosis D
0.000 0.833 0.167
E67.2 Megavitamin-B6 syndrome
0.000 0.833 0.167
E67.1 Hypercarotenaemia
0.000 0.833 0.167
E67.0 Hypervitaminosis A
0.000 0.833 0.167
E53.9 Vitamin B deficiency, unspecified
0.000 0.834 0.166
E53.1 Pyridoxine deficiency
0.000 0.834 0.166
E53.0 Riboflavin deficiency
0.000 0.834 0.166
E65 Localised adiposity
0.000 0.836 0.164
E03.5 Myxoedema coma
0.000 0.838 0.161
E03.4 Atrophy of thyroid (acquired)
0.000 0.838 0.161
E03.3 Postinfectious hypothyroidism
0.000 0.838 0.161
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.838 0.161
E06 Thyroiditis
0.001 0.848 0.151
E55.0 Rickets, active
0.000 0.849 0.151
E07.9 Disorder of thyroid, unspecified
0.000 0.871 0.129
E83.5 Disorders of calcium metabolism
0.127 0.873 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.878 0.122
E11.3 With ophthalmic complications
0.000 0.886 0.114
E06.4 Drug-induced thyroiditis
0.001 0.890 0.108
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.001 0.890 0.108
E06.1 Subacute thyroiditis
0.001 0.890 0.108
E06.0 Acute thyroiditis
0.001 0.890 0.108
E06.5 Other chronic thyroiditis
0.001 0.900 0.099
E53.8 Deficiency of other specified B group vitamins
0.000 0.901 0.099
E11.9 Without complications
0.000 0.901 0.099
E06.9 Thyroiditis, unspecified
0.001 0.912 0.087
E21.0 Primary hyperparathyroidism
0.000 0.919 0.081
E55.9 Vitamin D deficiency, unspecified
0.000 0.934 0.066
E66 Obesity
0.000 0.947 0.053
K52 Other non-infective gastro-enteritis and colitis
0.051 0.949 0.000
E04 Other non-toxic goitre
0.000 0.952 0.047
K52.0 Gastro-enteritis and colitis due to radiation
0.042 0.958 0.000
E66.1 Drug-induced obesity
0.000 0.961 0.038
E04.8 Other specified non-toxic goitre
0.000 0.966 0.034
E66.0 Obesity due to excess calories
0.000 0.966 0.034
H54.0 Blindness, both eyes
0.000 0.967 0.033
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.031 0.968 0.000
E66.8 Other obesity
0.000 0.969 0.031
E04.9 Non-toxic goitre, unspecified
0.000 0.969 0.031
K90-K93 Other diseases of the digestive system
0.001 0.969 0.029
K52.3 Indeterminate colitis
0.027 0.973 0.000
H54 Blindness and low vision
0.000 0.975 0.025
E06.3 Autoimmune thyroiditis
0.002 0.975 0.023
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.975 0.024
K52.1 Toxic gastro-enteritis and colitis
0.024 0.976 0.000
H54.7 Unspecified visual loss
0.000 0.977 0.023
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.978 0.021
E04.0 Non-toxic diffuse goitre
0.000 0.979 0.020
H54.6 Unqualified visual loss, one eye
0.000 0.980 0.020
H54.5 Low vision, one eye
0.000 0.981 0.019
H54.4 Blindness, one eye
0.000 0.982 0.018
H54.3 Unqualified visual loss, both eyes
0.000 0.982 0.018
H54.9 Unspecified visual impairment (binocular)
0.000 0.982 0.018
Q23.1 Congenital insufficiency of aortic valve
0.018 0.982 0.000
Q23 Congenital malformations of aortic and mitral valves
0.018 0.982 0.000
Q23.0 Congenital stenosis of aortic valve
0.017 0.983 0.000
A08.4 Viral intestinal infection, unspecified
0.000 0.983 0.017
H54.1 Blindness, one eye, low vision, other eye
0.000 0.983 0.017
H54.2 Low vision, both eyes
0.000 0.983 0.017
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.984 0.015
K93.1 Megacolon in Chagas' disease
0.001 0.984 0.015
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.984 0.015
Q20-Q28 Congenital malformations of the circulatory system
0.015 0.985 0.000
Q21 Congenital malformations of cardiac septa
0.015 0.985 0.000
Q21.0 Ventricular septal defect
0.015 0.985 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.013 0.987 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.013 0.987 0.000
Q23.4 Hypoplastic left heart syndrome
0.013 0.987 0.000
Q23.3 Congenital mitral insufficiency
0.013 0.987 0.000
Q23.2 Congenital mitral stenosis
0.013 0.987 0.000
Q27 Other congenital malformations of peripheral vascular system
0.013 0.987 0.000
Q21.3 Tetralogy of Fallot
0.012 0.988 0.000
Q26 Congenital malformations of great veins
0.012 0.988 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.012 0.988 0.000
M31.6 Other giant cell arteritis
0.000 0.988 0.012
Q25 Congenital malformations of great arteries
0.012 0.988 0.000
Q28 Other congenital malformations of circulatory system
0.012 0.988 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.011 0.989 0.000
Q21.1 Atrial septal defect
0.011 0.989 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.989 0.011
Q21.8 Other congenital malformations of cardiac septa
0.011 0.989 0.000
Q21.4 Aortopulmonary septal defect
0.011 0.989 0.000
Q21.2 Atrioventricular septal defect
0.011 0.989 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.989 0.011
E70-E90 Metabolic disorders
0.005 0.989 0.006
Q27.8 Other specified congenital malformations of peripheral vascular system
0.011 0.989 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.011 0.989 0.000
Q24 Other congenital malformations of heart
0.010 0.990 0.000
I84.6 Residual haemorrhoidal skin tags
0.010 0.990 0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified
0.010 0.990 0.000
C43.5 Malignant melanoma of trunk
0.000 0.991 0.009
Q25.7 Other congenital malformations of pulmonary artery
0.009 0.991 0.000
Q27.4 Congenital phlebectasia
0.009 0.991 0.000
Q27.2 Other congenital malformations of renal artery
0.009 0.991 0.000
Q27.1 Congenital renal artery stenosis
0.009 0.991 0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.009 0.991 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.009 0.991 0.000
Q26.9 Congenital malformation of great vein, unspecified
0.009 0.991 0.000
Q26.8 Other congenital malformations of great veins
0.009 0.991 0.000
Q26.6 Portal vein-hepatic artery fistula
0.009 0.991 0.000
Q26.5 Anomalous portal venous connexion
0.009 0.991 0.000
Q26.3 Partial anomalous pulmonary venous connexion
0.009 0.991 0.000
Q26.2 Total anomalous pulmonary venous connexion
0.009 0.991 0.000
Q26.1 Persistent left superior vena cava
0.009 0.991 0.000
Q26.0 Congenital stenosis of vena cava
0.009 0.991 0.000
Q24.8 Other specified congenital malformations of heart
0.009 0.991 0.000
Q25.1 Coarctation of aorta
0.009 0.991 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.009 0.991 0.000
Q25.6 Stenosis of pulmonary artery
0.009 0.991 0.000
Q27.3 Peripheral arteriovenous malformation
0.009 0.991 0.000
Q25.4 Other congenital malformations of aorta
0.009 0.991 0.000
Q25.9 Congenital malformation of great arteries, unspecified
0.008 0.991 0.000
Q25.8 Other congenital malformations of great arteries
0.008 0.991 0.000
Q25.5 Atresia of pulmonary artery
0.008 0.991 0.000
Q25.2 Atresia of aorta
0.008 0.991 0.000
Q28.9 Congenital malformation of circulatory system, unspecified
0.008 0.991 0.000
Q28.8 Other specified congenital malformations of circulatory system
0.008 0.991 0.000
Q28.1 Other malformations of precerebral vessels
0.008 0.991 0.000
Q28.0 Arteriovenous malformation of precerebral vessels
0.008 0.991 0.000
E73 Lactose intolerance
0.003 0.992 0.006
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified
0.008 0.992 0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions
0.008 0.992 0.000
Q20.6 Isomerism of atrial appendages
0.008 0.992 0.000
Q20.5 Discordant atrioventricular connexion
0.008 0.992 0.000
Q20.4 Double inlet ventricle
0.008 0.992 0.000
Q20.3 Discordant ventriculoarterial connexion
0.008 0.992 0.000
Q20.2 Double outlet left ventricle
0.008 0.992 0.000
Q20.1 Double outlet right ventricle
0.008 0.992 0.000
Q20.0 Common arterial trunk
0.008 0.992 0.000
Q28.3 Other malformations of cerebral vessels
0.008 0.992 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.992 0.008
Q22.5 Ebstein's anomaly
0.008 0.992 0.000
E77 Disorders of glycoprotein metabolism
0.004 0.992 0.004
E76 Disorders of glycosaminoglycan metabolism
0.004 0.992 0.004
E72 Other disorders of amino-acid metabolism
0.004 0.992 0.004
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.004 0.992 0.004
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.004 0.992 0.004
Q25.3 Stenosis of aorta
0.008 0.992 0.000
E70 Disorders of aromatic amino-acid metabolism
0.004 0.992 0.004
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.004 0.992 0.005
Q25.0 Patent ductus arteriosus
0.008 0.992 0.000
E84 Cystic fibrosis
0.004 0.992 0.004
Q22.9 Congenital malformation of tricuspid valve, unspecified
0.008 0.992 0.000
Q22.8 Other congenital malformations of tricuspid valve
0.008 0.992 0.000
Q22.6 Hypoplastic right heart syndrome
0.008 0.992 0.000
Q22.4 Congenital tricuspid stenosis
0.008 0.992 0.000
Q22.3 Other congenital malformations of pulmonary valve
0.008 0.992 0.000
Q22.2 Congenital pulmonary valve insufficiency
0.008 0.992 0.000
Q22.0 Pulmonary valve atresia
0.008 0.992 0.000
E79 Disorders of purine and pyrimidine metabolism
0.004 0.992 0.004
J38.3 Other diseases of vocal cords
0.008 0.992 0.000
Q24.6 Congenital heart block
0.008 0.992 0.000
J38.4 Oedema of larynx
0.008 0.992 0.000
Q24.4 Congenital subaortic stenosis
0.007 0.992 0.000
Q24.3 Pulmonary infundibular stenosis
0.007 0.992 0.000
Q24.2 Cor triatriatum
0.007 0.992 0.000
Q24.1 Levocardia
0.007 0.992 0.000
E74 Other disorders of carbohydrate metabolism
0.004 0.992 0.004
Q24.0 Dextrocardia
0.007 0.992 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.008 0.992 0.000
Q22.1 Congenital pulmonary valve stenosis
0.007 0.993 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.993 0.007
E85 Amyloidosis
0.003 0.993 0.004
E88 Other metabolic disorders
0.004 0.993 0.003
Q24.5 Malformation of coronary vessels
0.007 0.993 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.993 0.007
E73.9 Lactose intolerance, unspecified
0.001 0.993 0.006
E80 Disorders of porphyrin and bilirubin metabolism
0.003 0.993 0.003
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.006 0.994 0.000
E73.8 Other lactose intolerance
0.002 0.994 0.004
E73.1 Secondary lactase deficiency
0.002 0.994 0.004
E73.0 Congenital lactase deficiency
0.002 0.994 0.004
E71.3 Disorders of fatty-acid metabolism
0.003 0.994 0.003
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.003 0.994 0.003
E71.1 Other disorders of branched-chain amino-acid metabolism
0.003 0.994 0.003
E71.0 Maple-syrup-urine disease
0.003 0.994 0.003
E72.9 Disorder of amino-acid metabolism, unspecified
0.003 0.994 0.003
E72.8 Other specified disorders of amino-acid metabolism
0.003 0.994 0.003
E72.5 Disorders of glycine metabolism
0.003 0.994 0.003
E72.4 Disorders of ornithine metabolism
0.003 0.994 0.003
E72.3 Disorders of lysine and hydroxylysine metabolism
0.003 0.994 0.003
E72.2 Disorders of urea cycle metabolism
0.003 0.994 0.003
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.003 0.994 0.003
E72.0 Disorders of amino-acid transport
0.003 0.994 0.003
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.003 0.994 0.003
E76.8 Other disorders of glucosaminoglycan metabolism
0.003 0.994 0.003
E76.3 Mucopolysaccharidosis, unspecified
0.003 0.994 0.003
E76.2 Other mucopolysaccharidoses
0.003 0.994 0.003
E76.1 Mucopolysaccharidosis, type II
0.003 0.994 0.003
E76.0 Mucopolysaccharidosis, type I
0.003 0.994 0.003
E77.9 Disorder of glycoprotein metabolism, unspecified
0.003 0.994 0.003
E77.8 Other disorders of glycoprotein metabolism
0.003 0.994 0.003
E77.1 Defects in glycoprotein degradation
0.003 0.994 0.003
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.003 0.994 0.003
K52.8 Other specified non-infective gastro-enteritis and colitis
0.006 0.994 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.994 0.006
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.003 0.994 0.003
E70.8 Other disorders of aromatic amino-acid metabolism
0.003 0.994 0.003
E70.2 Disorders of tyrosine metabolism
0.003 0.994 0.003
E70.1 Other hyperphenylalaninaemias
0.003 0.994 0.003
E70.0 Classical phenylketonuria
0.003 0.994 0.003
E75.6 Lipid storage disorder, unspecified
0.003 0.994 0.003
E75.4 Neuronal ceroid lipofuscinosis
0.003 0.994 0.003
E75.3 Sphingolipidosis, unspecified
0.003 0.994 0.003
E75.1 Other gangliosidosis
0.003 0.994 0.003
E75.0 GM2 gangliosidosis
0.003 0.994 0.003
E84.8 Cystic fibrosis with other manifestations
0.003 0.994 0.003
E84.1 Cystic fibrosis with intestinal manifestations
0.003 0.994 0.003
E84.0 Cystic fibrosis with pulmonary manifestations
0.003 0.994 0.003
E75.5 Other lipid storage disorders
0.002 0.994 0.004
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.003 0.994 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.003 0.994 0.003
E79.1 Lesch-Nyhan syndrome
0.003 0.994 0.003
E70.3 Albinism
0.003 0.994 0.003
E75.2 Other sphingolipidosis
0.003 0.994 0.003
E84.9 Cystic fibrosis, unspecified
0.003 0.994 0.003
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.003 0.994 0.003
E74.9 Disorder of carbohydrate metabolism, unspecified
0.003 0.994 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.003 0.994 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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