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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094606
log Bayes Factor = 38.3802
Chromosome 6   position 31,173,678  (GRCh37) Explore rs3094606 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
L40 Psoriasis
0.000 0.002 0.998
E11.9 Without complications
0.000 0.002 0.998
M06.9 Rheumatoid arthritis, unspecified
0.000 0.002 0.998
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
I25.2 Old myocardial infarction
0.000 0.004 0.996
I20-I25 Ischaemic heart diseases
0.000 0.004 0.996
L40.5 Arthropathic psoriasis
0.000 0.014 0.986
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.016 0.984
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.016 0.984
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.021 0.979
I25.5 Ischaemic cardiomyopathy
0.000 0.025 0.975
E14 Unspecified diabetes mellitus
0.000 0.026 0.974
I25.1 Atherosclerotic heart disease
0.000 0.028 0.972
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.039 0.961
E10.3 With ophthalmic complications
0.000 0.039 0.961
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.042 0.958
E70-E90 Metabolic disorders
0.000 0.043 0.957
E14.9 Without complications
0.000 0.044 0.956
I22 Subsequent myocardial infarction
0.000 0.051 0.949
I24 Other acute ischaemic heart diseases
0.000 0.060 0.940
I21 Acute myocardial infarction
0.000 0.067 0.933
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.070 0.930
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.070 0.930
L40-L45 Papulosquamous disorders
0.000 0.078 0.922
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.082 0.918
L43 Lichen planus
0.000 0.104 0.896
L43.9 Lichen planus, unspecified
0.000 0.123 0.877
E11.0 With coma
0.000 0.126 0.874
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.127 0.873
G35-G37 Demyelinating diseases of the central nervous system
0.872 0.128 0.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.133 0.867
I21.4 Acute subendocardial myocardial infarction
0.000 0.135 0.865
E13 Other specified diabetes mellitus
0.000 0.144 0.856
E10.4 With neurological complications
0.000 0.149 0.851
E78.8 Other disorders of lipoprotein metabolism
0.000 0.154 0.846
G37 Other demyelinating diseases of central nervous system
0.844 0.155 0.000
E10.1 With ketoacidosis
0.000 0.158 0.842
E78.2 Mixed hyperlipidaemia
0.000 0.159 0.841
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.160 0.840
E11.1 With ketoacidosis
0.000 0.162 0.838
L40.8 Other psoriasis
0.000 0.166 0.834
I10 Essential (primary) hypertension
0.000 0.167 0.833
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.180 0.820
G37.9 Demyelinating disease of central nervous system, unspecified
0.813 0.187 0.000
L40.0 Psoriasis vulgaris
0.000 0.187 0.813
I10-I15 Hypertensive diseases
0.000 0.195 0.805
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.207 0.793
E74 Other disorders of carbohydrate metabolism
0.000 0.208 0.792
E10.8 With unspecified complications
0.000 0.208 0.792
E11.2 With renal complications
0.000 0.211 0.789
E10.0 With coma
0.000 0.214 0.786
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.216 0.784
I25.3 Aneurysm of heart
0.000 0.221 0.779
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.222 0.778
E11.5 With peripheral circulatory complications
0.000 0.222 0.778
I24.8 Other forms of acute ischaemic heart disease
0.000 0.224 0.776
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.228 0.772
E78.5 Hyperlipidaemia, unspecified
0.000 0.231 0.769
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.234 0.766
E83 Disorders of mineral metabolism
0.455 0.242 0.303
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.243 0.757
E10.5 With peripheral circulatory complications
0.000 0.246 0.754
E10.6 With other specified complications
0.000 0.248 0.752
E13.9 Without complications
0.000 0.248 0.752
E11.6 With other specified complications
0.000 0.248 0.752
I12 Hypertensive renal disease
0.000 0.253 0.747
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.256 0.744
E00-E07 Disorders of thyroid gland
0.000 0.264 0.736
E10.2 With renal complications
0.000 0.268 0.731
J45.9 Asthma, unspecified
0.000 0.269 0.731
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.270 0.730
E14.3 With ophthalmic complications
0.000 0.272 0.728
I22.8 Subsequent myocardial infarction of other sites
0.000 0.272 0.728
E11.4 With neurological complications
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.3 Pustulosis palmaris et plantaris
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L40.1 Generalised pustular psoriasis
0.000 0.284 0.716
I23 Certain current complications following acute myocardial infarction
0.000 0.286 0.714
E03 Other hypothyroidism
0.000 0.290 0.710
Chapter IX Diseases of the circulatory system
0.000 0.294 0.706
E78.6 Lipoprotein deficiency
0.000 0.295 0.705
E78.3 Hyperchylomicronaemia
0.000 0.295 0.705
E78.1 Pure hyperglyceridaemia
0.000 0.298 0.702
E14.8 With unspecified complications
0.000 0.302 0.698
E14.7 With multiple complications
0.000 0.302 0.698
E14.6 With other specified complications
0.000 0.302 0.698
E14.5 With peripheral circulatory complications
0.000 0.302 0.698
E14.2 Withrenal complications
0.000 0.302 0.698
E14.1 With ketoacidosis
0.000 0.302 0.698
E14.0 With coma
0.000 0.302 0.698
E03.9 Hypothyroidism, unspecified
0.000 0.308 0.692
I12.9 Hypertensive renal disease without renal failure
0.000 0.310 0.690
E79 Disorders of purine and pyrimidine metabolism
0.000 0.314 0.686
E77 Disorders of glycoprotein metabolism
0.000 0.314 0.686
E76 Disorders of glycosaminoglycan metabolism
0.000 0.314 0.686
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.314 0.686
E72 Other disorders of amino-acid metabolism
0.000 0.314 0.686
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.314 0.686
E70 Disorders of aromatic amino-acid metabolism
0.000 0.314 0.686
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.314 0.686
G37.8 Other specified demyelinating diseases of central nervous system
0.683 0.317 0.000
L42 Pityriasis rosea
0.000 0.317 0.683
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.327 0.673
E78.4 Other hyperlipidaemia
0.000 0.328 0.672
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.331 0.669
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.339 0.661
L44 Other papulosquamous disorders
0.000 0.339 0.661
L41 Parapsoriasis
0.000 0.339 0.661
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.339 0.661
E84 Cystic fibrosis
0.000 0.340 0.660
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.343 0.657
E14.4 With neurological complications
0.000 0.347 0.652
M06 Other rheumatoid arthritis
0.000 0.353 0.647
L43.8 Other lichen planus
0.000 0.353 0.647
L43.3 Subacute (active) lichen planus
0.000 0.358 0.642
L43.2 Lichenoid drug reaction
0.000 0.358 0.642
L43.1 Bullous lichen planus
0.000 0.358 0.642
L43.0 Hypertrophic lichen planus
0.000 0.358 0.642
E50-E64 Other nutritional deficiencies
0.000 0.367 0.632
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.626 0.373 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.374 0.626
G36 Other acute disseminated demyelination
0.625 0.375 0.000
E40-E46 Malnutrition
0.000 0.375 0.625
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.377 0.623
I15 Secondary hypertension
0.000 0.380 0.620
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.380 0.620
I24.1 Dressler's syndrome
0.000 0.384 0.616
E13.8 With unspecified complications
0.000 0.386 0.613
E13.7 With multiple complications
0.000 0.386 0.613
E13.6 With other specified complications
0.000 0.386 0.613
E13.5 With peripheral circulatory complications
0.000 0.386 0.613
E13.4 With neurological complications
0.000 0.386 0.613
E13.3 With ophthalmic complications
0.000 0.386 0.613
E13.2 With renal complications
0.000 0.386 0.613
E13.1 With ketoacidosis
0.000 0.386 0.613
E13.0 With coma
0.000 0.386 0.613
E73 Lactose intolerance
0.000 0.391 0.609
G37.5 Concentric sclerosis [Balo]
0.605 0.394 0.000
G37.4 Subacute necrotising myelitis
0.605 0.394 0.000
G37.2 Central pontine myelinolysis
0.605 0.394 0.000
G37.1 Central demyelination of corpus callosum
0.605 0.394 0.000
G37.0 Diffuse sclerosis
0.605 0.394 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.407 0.593
E16 Other disorders of pancreatic internal secretion
0.000 0.412 0.588
I11 Hypertensive heart disease
0.000 0.413 0.587
I25.4 Coronary artery aneurysm
0.000 0.417 0.583
E85 Amyloidosis
0.000 0.418 0.581
I13 Hypertensive heart and renal disease
0.000 0.423 0.577
I20 Angina pectoris
0.000 0.423 0.577
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.432 0.568
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.432 0.568
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.432 0.568
E74.2 Disorders of galactose metabolism
0.000 0.432 0.568
E74.1 Disorders of fructose metabolism
0.000 0.432 0.568
E74.0 Glycogen storage disease
0.000 0.432 0.568
E89.3 Postprocedural hypopituitarism
0.000 0.438 0.562
E07 Other disorders of thyroid
0.000 0.441 0.559
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.445 0.555
E61 Deficiency of other nutrient elements
0.000 0.447 0.553
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.550 0.450 0.000
E11.8 With unspecified complications
0.000 0.452 0.548
E83.9 Disorder of mineral metabolism, unspecified
0.326 0.456 0.217
E83.8 Other disorders of mineral metabolism
0.326 0.456 0.217
E83.2 Disorders of zinc metabolism
0.326 0.456 0.217
E83.0 Disorders of copper metabolism
0.326 0.456 0.217
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.458 0.542
E28 Ovarian dysfunction
0.000 0.459 0.541
E88 Other metabolic disorders
0.000 0.461 0.539
E23 Hypofunction and other disorders of pituitary gland
0.000 0.465 0.535
E15 Nondiabetic hypoglycaemic coma
0.000 0.467 0.533
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.472 0.528
E00 Congenital iodine-deficiency syndrome
0.000 0.472 0.528
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.474 0.526
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
I23.8 Other current complications following acute myocardial infarction
0.000 0.488 0.512
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.488 0.512
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.488 0.512
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.488 0.512
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.488 0.512
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.488 0.512
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.488 0.512
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.488 0.512
E03.5 Myxoedema coma
0.000 0.491 0.509
E03.4 Atrophy of thyroid (acquired)
0.000 0.491 0.509
E03.3 Postinfectious hypothyroidism
0.000 0.491 0.509
E03.1 Congenital hypothyroidism without goitre
0.000 0.491 0.509
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.491 0.509
E24 Cushing's syndrome
0.000 0.492 0.508
I00-I02 Acute rheumatic fever
0.000 0.494 0.506
E28.2 Polycystic ovarian syndrome
0.000 0.496 0.504
I20.9 Angina pectoris, unspecified
0.000 0.498 0.502
E61.1 Iron deficiency
0.000 0.502 0.498
M06.4 Inflammatory polyarthropathy
0.000 0.504 0.496
E83.3 Disorders of phosphorus metabolism
0.376 0.505 0.119
M06.3 Rheumatoid nodule
0.000 0.507 0.493
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.508 0.492
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.508 0.492
E70.3 Albinism
0.000 0.508 0.492
E70.2 Disorders of tyrosine metabolism
0.000 0.508 0.492
E70.1 Other hyperphenylalaninaemias
0.000 0.508 0.492
E70.0 Classical phenylketonuria
0.000 0.508 0.492
E71.3 Disorders of fatty-acid metabolism
0.000 0.508 0.492
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.508 0.492
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.508 0.492
E71.0 Maple-syrup-urine disease
0.000 0.508 0.492
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.508 0.492
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.508 0.492
E72.5 Disorders of glycine metabolism
0.000 0.508 0.492
E72.4 Disorders of ornithine metabolism
0.000 0.508 0.492
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.508 0.492
E72.2 Disorders of urea cycle metabolism
0.000 0.508 0.492
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.508 0.492
E72.0 Disorders of amino-acid transport
0.000 0.508 0.492
E75.6 Lipid storage disorder, unspecified
0.000 0.508 0.492
E75.5 Other lipid storage disorders
0.000 0.508 0.492
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.508 0.492
E75.3 Sphingolipidosis, unspecified
0.000 0.508 0.492
E75.2 Other sphingolipidosis
0.000 0.508 0.492
E75.1 Other gangliosidosis
0.000 0.508 0.492
E75.0 GM2 gangliosidosis
0.000 0.508 0.492
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.508 0.492
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.508 0.492
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.508 0.492
E76.2 Other mucopolysaccharidoses
0.000 0.508 0.492
E76.1 Mucopolysaccharidosis, type II
0.000 0.508 0.492
E76.0 Mucopolysaccharidosis, type I
0.000 0.508 0.492
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.508 0.492
E77.8 Other disorders of glycoprotein metabolism
0.000 0.508 0.492
E77.1 Defects in glycoprotein degradation
0.000 0.508 0.492
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.508 0.492
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.508 0.492
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.508 0.492
E79.1 Lesch-Nyhan syndrome
0.000 0.508 0.492
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.508 0.492
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.510 0.490
I15.1 Hypertension secondary to other renal disorders
0.000 0.513 0.487
E26 Hyperaldosteronism
0.000 0.515 0.485
K90 Intestinal malabsorption
0.000 0.519 0.481
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.521 0.479
L41.9 Parapsoriasis, unspecified
0.000 0.526 0.474
L41.8 Other parapsoriasis
0.000 0.526 0.474
L41.5 Retiform parapsoriasis
0.000 0.526 0.474
L41.4 Large plaque parapsoriasis
0.000 0.526 0.474
L41.3 Small plaque parapsoriasis
0.000 0.526 0.474
L41.2 Lymphomatoid papulosis
0.000 0.526 0.474
L41.1 Pityriasis lichenoides chronica
0.000 0.526 0.474
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.526 0.474
L44.9 Papulosquamous disorder, unspecified
0.000 0.526 0.474
L44.8 Other specified papulosquamous disorders
0.000 0.526 0.474
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.526 0.474
L44.3 Lichen ruber moniliformis
0.000 0.526 0.474
L44.2 Lichen striatus
0.000 0.526 0.474
L44.1 Lichen nitidus
0.000 0.526 0.474
L44.0 Pityriasis rubra pilaris
0.000 0.526 0.474
E03.8 Other specified hypothyroidism
0.000 0.526 0.473
E84.8 Cystic fibrosis with other manifestations
0.000 0.527 0.473
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.527 0.473
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.527 0.473
K51.9 Ulcerative colitis, unspecified
0.469 0.531 0.000
K51 Ulcerative colitis
0.468 0.532 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.536 0.464
M06.2 Rheumatoid bursitis
0.000 0.536 0.464
M06.1 Adult-onset Still's disease
0.000 0.536 0.464
E16.2 Hypoglycaemia, unspecified
0.000 0.540 0.460
E23.2 Diabetes insipidus
0.000 0.543 0.457
E65-E68 Obesity and other hyperalimentation
0.000 0.546 0.454
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.546 0.453
E63 Other nutritional deficiencies
0.000 0.546 0.453
E56 Other vitamin deficiencies
0.000 0.546 0.453
E51 Thiamine deficiency
0.000 0.546 0.453
E50 Vitamin A deficiency
0.000 0.546 0.453
E60 Dietary zinc deficiency
0.000 0.546 0.453
E59 Dietary selenium deficiency
0.000 0.546 0.453
E58 Dietary calcium deficiency
0.000 0.546 0.453
E54 Ascorbic acid deficiency
0.000 0.546 0.453
E52 Niacin deficiency [pellagra]
0.000 0.546 0.453
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.551 0.449
E32 Diseases of thymus
0.000 0.551 0.449
E31 Polyglandular dysfunction
0.000 0.551 0.449
E30 Disorders of puberty, not elsewhere classified
0.000 0.551 0.449
E25 Adrenogenital disorders
0.000 0.551 0.449
G36.9 Acute disseminated demyelination, unspecified
0.448 0.551 0.000
G36.8 Other specified acute disseminated demyelination
0.448 0.551 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.448 0.551 0.000
G36.0 Neuromyelitis optica [Devic]
0.448 0.551 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.552 0.448
E45 Retarded development following protein-energy malnutrition
0.000 0.552 0.448
E43 Unspecified severe protein-energy malnutrition
0.000 0.552 0.448
E42 Marasmic kwashiorkor
0.000 0.552 0.448
E41 Nutritional marasmus
0.000 0.552 0.448
E40 Kwashiorkor
0.000 0.552 0.448
E84.9 Cystic fibrosis, unspecified
0.000 0.552 0.447
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.553 0.447
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.553 0.447
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.553 0.447
E89.5 Postprocedural testicular hypofunction
0.000 0.553 0.447
E89.1 Postprocedural hypoinsulinaemia
0.000 0.553 0.447
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.554 0.446
I15.9 Seconday hypertension, unspecified
0.000 0.555 0.444
I15.8 Other secondary hypertension
0.000 0.555 0.444
I15.2 Hypertension secondary to endocrine disorders
0.000 0.555 0.444
I15.0 Renovascular hypertension
0.000 0.555 0.444
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.557 0.443
E05.9 Thyrotoxicosis, unspecified
0.000 0.557 0.443
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.557 0.442
K51.3 Ulcerative (chronic) rectosigmoiditis
0.440 0.560 0.000
E73.8 Other lactose intolerance
0.000 0.563 0.437
E73.1 Secondary lactase deficiency
0.000 0.563 0.437
E73.0 Congenital lactase deficiency
0.000 0.563 0.437
I83 Varicose veins of lower extremities
0.433 0.564 0.003
E29 Testicular dysfunction
0.000 0.567 0.433
E07.9 Disorder of thyroid, unspecified
0.000 0.569 0.431
E89.4 Postprocedural ovarian failure
0.000 0.570 0.430
K51.4 Pseudopolyposis of colon
0.430 0.570 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.571 0.428
I20.1 Angina pectoris with documented spasm
0.000 0.574 0.426
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.577 0.423
E24.9 Cushing's syndrome, unspecified
0.000 0.577 0.423
K51.8 Other ulcerative colitis
0.422 0.578 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.578 0.421
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.578 0.421
E16.4 Abnormal secretion of gastrin
0.000 0.578 0.421
E16.3 Increased secretion of glucagon
0.000 0.578 0.421
E16.1 Other hypoglycaemia
0.000 0.578 0.421
M45 Ankylosing spondylitis
0.000 0.580 0.420
E06 Thyroiditis
0.000 0.581 0.419
E85.8 Other amyloidosis
0.000 0.583 0.417
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.583 0.417
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.583 0.417
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.583 0.417
E89.2 Postprocedural hypoparathyroidism
0.000 0.584 0.415
M05-M14 Inflammatory polyarthropathies
0.000 0.585 0.415
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.586 0.414
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.586 0.414
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.586 0.414
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.586 0.414
E88.2 Lipomatosis, not elsewhere classified
0.000 0.587 0.413
E85.9 Amyloidosis, unspecified
0.000 0.589 0.410
E23.6 Other disorders of pituitary gland
0.000 0.591 0.409
I83.0 Varicose veins of lower extremities with ulcer
0.402 0.597 0.001
E07.8 Other specified disorders of thyroid
0.000 0.599 0.401
E07.1 Dyshormogenetic goitre
0.000 0.599 0.401
E07.0 Hypersecretion of calcitonin
0.000 0.599 0.401
E23.7 Disorder of pituitary gland, unspecified
0.000 0.600 0.400
E61.9 Deficiency of nutrient element, unspecified
0.000 0.603 0.397
E61.8 Deficiency of other specified nutrient elements
0.000 0.603 0.397
E61.7 Deficiency of multiple nutrient elements
0.000 0.603 0.397
E61.6 Vanadium deficiency
0.000 0.603 0.397
E61.5 Molybdenum deficiency
0.000 0.603 0.397
E61.4 Chromium deficiency
0.000 0.603 0.397
E61.3 Manganese deficiency
0.000 0.603 0.397
E61.0 Copper deficiency
0.000 0.603 0.397
I05-I09 Chronic rheumatic heart diseases
0.000 0.604 0.396
E80.6 Other disorders of bilirubin metabolism
0.000 0.604 0.395
E55 Vitamin D deficiency
0.000 0.607 0.393
E83.5 Disorders of calcium metabolism
0.367 0.607 0.026
E61.2 Magnesium deficiency
0.000 0.608 0.392
K51.5 Mucosal proctocolitis
0.390 0.610 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.610 0.390
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.611 0.388
E80.5 Crigler-Najjar syndrome
0.000 0.611 0.388
E80.3 Defects of catalase and peroxydase
0.000 0.611 0.388
E80.2 Other porphyria
0.000 0.611 0.388
E80.1 Porphyria cutanea tarda
0.000 0.611 0.388
E80.0 Hereditary erythropoietic porphyria
0.000 0.611 0.388
E28.9 Ovarian dysfunction, unspecified
0.000 0.612 0.388
E28.8 Other ovarian dysfunction
0.000 0.612 0.388
E28.1 Androgen excess
0.000 0.612 0.388
E28.0 Oestrogen excess
0.000 0.612 0.388
E88.9 Metabolic disorder, unspecified
0.000 0.613 0.386
E88.8 Other specified metabolic disorders
0.000 0.613 0.386
E88.3 Tumour lysis syndrome
0.000 0.613 0.386
E46 Unspecified protein-energy malnutrition
0.000 0.616 0.384
E26.0 Primary hyperaldosteronism
0.000 0.616 0.384
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.616 0.384
E23.1 Drug-induced hypopituitarism
0.000 0.616 0.384
K51.2 Ulcerative (chronic) proctitis
0.382 0.618 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.621 0.379
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.621 0.378
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.621 0.378
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.621 0.378
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.621 0.378
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.621 0.378
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.621 0.378
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.621 0.378
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.621 0.378
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.622 0.378
E85.3 Secondary systemic amyloidosis
0.000 0.623 0.376
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.624 0.376
E20 Hypoparathyroidism
0.000 0.625 0.374
E85.4 Organ-limited amyloidosis
0.000 0.626 0.373
M45-M49 Spondylopathies
0.000 0.630 0.370
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.632 0.368
E22 Hyperfunction of pituitary gland
0.000 0.634 0.366
E23.0 Hypopituitarism
0.000 0.635 0.365
E24.8 Other Cushing's syndrome
0.000 0.636 0.364
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.636 0.364
E24.3 Ectopic ACTH syndrome
0.000 0.636 0.364
E24.2 Drug-induced Cushing's syndrome
0.000 0.636 0.364
E24.1 Nelson's syndrome
0.000 0.636 0.364
E24.0 Pituitary-dependent Cushing's disease
0.000 0.636 0.364
I02 Rheumatic chorea
0.000 0.637 0.363
I01 Rheumatic fever with heart involvement
0.000 0.637 0.363
I00 Rheumatic fever without mention of heart involvement
0.000 0.637 0.363
M06.0 Seronegative rheumatoid arthritis
0.000 0.638 0.362
E73.9 Lactose intolerance, unspecified
0.001 0.640 0.360
E83.4 Disorders of magnesium metabolism
0.077 0.641 0.282
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.642 0.358
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.356 0.643 0.002
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.644 0.356
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.644 0.356
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.644 0.356
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.644 0.356
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.644 0.356
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.644 0.356
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.644 0.356
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.644 0.356
M70-M79 Other soft tissue disorders
0.000 0.644 0.356
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.647 0.353
M06.38 Rheumatoid nodule (Other)
0.000 0.647 0.353
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.647 0.353
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.647 0.353
M06.33 Rheumatoid nodule (Forearm)
0.000 0.647 0.353
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.647 0.353
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.647 0.353
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.647 0.353
K90.8 Other intestinal malabsorption
0.000 0.647 0.353
E05.5 Thyroid crisis or storm
0.000 0.649 0.351
E05.4 Thyrotoxicosis factitia
0.000 0.649 0.351
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.649 0.351
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.649 0.351
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.649 0.350
M07 Psoriatic and enteropathic arthropathies
0.000 0.650 0.350
E26.9 Hyperaldosteronism, unspecified
0.000 0.652 0.348
E26.8 Other hyperaldosteronism
0.000 0.652 0.348
E26.1 Secondary hyperaldosteronism
0.000 0.652 0.348
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.653 0.347
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.654 0.346
K90.3 Pancreatic steatorrhoea
0.000 0.655 0.345
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.655 0.345
K90.1 Tropical sprue
0.000 0.655 0.345
K90.9 Intestinal malabsorption, unspecified
0.000 0.656 0.344
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.657 0.342
M79.6 Pain in limb
0.000 0.658 0.342
K51.0 Ulcerative (chronic) enterocolitis
0.342 0.658 0.000
E34 Other endocrine disorders
0.000 0.658 0.341
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.663 0.337
K51.1 Ulcerative (chronic) ileocolitis
0.336 0.664 0.000
M75 Shoulder lesions
0.000 0.667 0.333
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.667 0.333
M06.18 Adult-onset Still's disease (Other)
0.000 0.667 0.333
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.667 0.333
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.667 0.333
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.667 0.333
M06.14 Adult-onset Still's disease (Hand)
0.000 0.667 0.333
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.667 0.333
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.667 0.333
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.667 0.333
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.667 0.333
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.667 0.333
M06.28 Rheumatoid bursitis (Other)
0.000 0.667 0.333
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.667 0.333
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.667 0.333
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.667 0.333
M06.24 Rheumatoid bursitis (Hand)
0.000 0.667 0.333
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.667 0.333
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.667 0.333
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.667 0.333
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.667 0.333
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.667 0.333
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.667 0.333
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.667 0.333
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.667 0.333
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.667 0.333
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.667 0.333
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.667 0.333

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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