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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094672
log Bayes Factor = 61.8926
Chromosome 6   position 30,993,377  (GRCh37) Explore rs3094672 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
L40 Psoriasis
0.996 0.004 0.000
E10-E14 Diabetes mellitus
0.000 0.005 0.995
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.006 0.994
E05.9 Thyrotoxicosis, unspecified
0.000 0.007 0.993
L40.5 Arthropathic psoriasis
0.993 0.007 0.000
E00-E07 Disorders of thyroid gland
0.000 0.012 0.988
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.012 0.988
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.021 0.979
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.041 0.959
E10.1 With ketoacidosis
0.000 0.055 0.945
E16 Other disorders of pancreatic internal secretion
0.000 0.062 0.938
E10.4 With neurological complications
0.000 0.072 0.928
E14 Unspecified diabetes mellitus
0.000 0.086 0.914
E10.2 With renal complications
0.000 0.119 0.881
E16.2 Hypoglycaemia, unspecified
0.000 0.120 0.880
E05.8 Other thyrotoxicosis
0.000 0.132 0.868
E07 Other disorders of thyroid
0.000 0.144 0.856
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.158 0.842
E10.0 With coma
0.000 0.164 0.836
L40.0 Psoriasis vulgaris
0.835 0.165 0.000
E10.8 With unspecified complications
0.000 0.186 0.814
E13 Other specified diabetes mellitus
0.000 0.187 0.813
E10.6 With other specified complications
0.000 0.203 0.797
L40.3 Pustulosis palmaris et plantaris
0.795 0.205 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.211 0.789
E40-E46 Malnutrition
0.000 0.234 0.766
E14.3 With ophthalmic complications
0.000 0.235 0.764
L40.1 Generalised pustular psoriasis
0.760 0.240 0.000
E16.1 Other hypoglycaemia
0.000 0.252 0.748
E14.8 With unspecified complications
0.000 0.271 0.729
E10.5 With peripheral circulatory complications
0.000 0.277 0.723
E14.9 Without complications
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.714 0.286 0.000
L40.2 Acrodermatitis continua
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.286 0.714
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.291 0.708
E00 Congenital iodine-deficiency syndrome
0.000 0.291 0.708
E14.6 With other specified complications
0.000 0.303 0.697
E14.1 With ketoacidosis
0.000 0.304 0.696
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.307 0.693
E15 Nondiabetic hypoglycaemic coma
0.000 0.313 0.687
E13.9 Without complications
0.000 0.318 0.682
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.328 0.672
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.328 0.672
E16.4 Abnormal secretion of gastrin
0.000 0.328 0.672
E16.3 Increased secretion of glucagon
0.000 0.328 0.672
E14.7 With multiple complications
0.000 0.345 0.655
E14.2 Withrenal complications
0.000 0.345 0.655
E14.0 With coma
0.000 0.345 0.655
E14.5 With peripheral circulatory complications
0.000 0.345 0.655
K90 Intestinal malabsorption
0.000 0.346 0.654
L40.8 Other psoriasis
0.648 0.352 0.000
E14.4 With neurological complications
0.000 0.353 0.647
E50-E64 Other nutritional deficiencies
0.000 0.383 0.617
E07.1 Dyshormogenetic goitre
0.000 0.386 0.614
E07.0 Hypersecretion of calcitonin
0.000 0.386 0.614
E46 Unspecified protein-energy malnutrition
0.000 0.393 0.607
E06 Thyroiditis
0.000 0.415 0.585
E13.3 With ophthalmic complications
0.000 0.416 0.584
E13.8 With unspecified complications
0.000 0.417 0.583
E13.7 With multiple complications
0.000 0.417 0.583
E13.6 With other specified complications
0.000 0.417 0.583
E13.5 With peripheral circulatory complications
0.000 0.417 0.583
E13.4 With neurological complications
0.000 0.417 0.583
E13.2 With renal complications
0.000 0.417 0.583
E13.1 With ketoacidosis
0.000 0.417 0.583
E13.0 With coma
0.000 0.417 0.583
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.449 0.551
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.451 0.549
E45 Retarded development following protein-energy malnutrition
0.000 0.451 0.549
E43 Unspecified severe protein-energy malnutrition
0.000 0.451 0.549
E42 Marasmic kwashiorkor
0.000 0.451 0.549
E41 Nutritional marasmus
0.000 0.451 0.549
E40 Kwashiorkor
0.000 0.451 0.549
K90.9 Intestinal malabsorption, unspecified
0.000 0.460 0.540
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.475 0.525
E03 Other hypothyroidism
0.000 0.476 0.524
E07.8 Other specified disorders of thyroid
0.000 0.486 0.514
E12.9 Without complications
0.000 0.488 0.512
E12.8 With unspecified complications
0.000 0.488 0.512
E12.7 With multiple complications
0.000 0.488 0.512
E12.6 With other specified complications
0.000 0.488 0.512
E12.5 With peripheral circulatory complications
0.000 0.488 0.512
E12.4 With neurological complications
0.000 0.488 0.512
E12.3 With ophthalmic complications
0.000 0.488 0.512
E12.2 With renal complications
0.000 0.488 0.512
E12.1 With ketoacidosis
0.000 0.488 0.512
E12.0 With coma
0.000 0.488 0.512
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.492 0.508
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.492 0.508
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.492 0.508
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.492 0.508
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.492 0.508
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.492 0.508
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.492 0.508
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.492 0.508
E61 Deficiency of other nutrient elements
0.000 0.514 0.486
K90.8 Other intestinal malabsorption
0.000 0.521 0.479
K90.3 Pancreatic steatorrhoea
0.000 0.531 0.469
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.531 0.469
K90.1 Tropical sprue
0.000 0.531 0.469
E51 Thiamine deficiency
0.000 0.532 0.468
E55 Vitamin D deficiency
0.000 0.557 0.443
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.558 0.442
E50 Vitamin A deficiency
0.000 0.558 0.442
E60 Dietary zinc deficiency
0.000 0.558 0.442
E59 Dietary selenium deficiency
0.000 0.558 0.442
E58 Dietary calcium deficiency
0.000 0.558 0.442
E54 Ascorbic acid deficiency
0.000 0.558 0.442
E52 Niacin deficiency [pellagra]
0.000 0.558 0.442
E06.9 Thyroiditis, unspecified
0.000 0.558 0.442
E56 Other vitamin deficiencies
0.000 0.575 0.424
E06.5 Other chronic thyroiditis
0.000 0.580 0.419
E06.4 Drug-induced thyroiditis
0.000 0.580 0.419
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.580 0.419
E06.1 Subacute thyroiditis
0.000 0.580 0.419
E06.0 Acute thyroiditis
0.000 0.580 0.419
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.586 0.414
E63 Other nutritional deficiencies
0.000 0.587 0.412
E44.1 Mild protein-energy malnutrition
0.000 0.606 0.394
E44.0 Moderate protein-energy malnutrition
0.000 0.606 0.394
E61.1 Iron deficiency
0.000 0.608 0.392
J45.9 Asthma, unspecified
0.000 0.608 0.392
E03.5 Myxoedema coma
0.000 0.624 0.376
E03.4 Atrophy of thyroid (acquired)
0.000 0.624 0.376
E03.3 Postinfectious hypothyroidism
0.000 0.624 0.376
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.624 0.376
E03.8 Other specified hypothyroidism
0.000 0.627 0.373
E65-E68 Obesity and other hyperalimentation
0.000 0.635 0.365
E51.2 Wernicke's encephalopathy
0.000 0.638 0.362
E11 Non-insulin-dependent diabetes mellitus
0.000 0.645 0.355
E61.9 Deficiency of nutrient element, unspecified
0.000 0.652 0.348
E61.8 Deficiency of other specified nutrient elements
0.000 0.652 0.348
E61.7 Deficiency of multiple nutrient elements
0.000 0.652 0.348
E61.6 Vanadium deficiency
0.000 0.652 0.348
E61.5 Molybdenum deficiency
0.000 0.652 0.348
E61.4 Chromium deficiency
0.000 0.652 0.348
E61.3 Manganese deficiency
0.000 0.652 0.348
E61.2 Magnesium deficiency
0.000 0.652 0.348
E61.0 Copper deficiency
0.000 0.652 0.348
E03.1 Congenital hypothyroidism without goitre
0.000 0.663 0.336
E51.9 Thiamine deficiency, unspecified
0.000 0.664 0.336
E51.8 Other manifestations of thiamine deficiency
0.000 0.664 0.336
E51.1 Beriberi
0.000 0.664 0.336
E55.9 Vitamin D deficiency, unspecified
0.000 0.682 0.318
E55.0 Rickets, active
0.000 0.682 0.317
E50.9 Vitamin A deficiency, unspecified
0.000 0.683 0.317
E50.8 Other manifestations of vitamin A deficiency
0.000 0.683 0.317
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.683 0.317
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.683 0.317
E50.5 Vitamin A deficiency with night blindness
0.000 0.683 0.317
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.683 0.317
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.683 0.317
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.683 0.317
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.683 0.317
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.683 0.317
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.683 0.317
E64.8 Sequelae of other nutritional deficiencies
0.000 0.683 0.317
E64.3 Sequelae of rickets
0.000 0.683 0.317
E64.2 Sequelae of vitamin C deficiency
0.000 0.683 0.317
E64.1 Sequelae of vitamin A deficiency
0.000 0.683 0.317
E64.0 Sequelae of protein-energy malnutrition
0.000 0.683 0.317
E11.0 With coma
0.000 0.684 0.316
E56.9 Vitamin deficiency, unspecified
0.000 0.695 0.304
E56.8 Deficiency of other vitamins
0.000 0.695 0.304
E56.0 Deficiency of vitamin E
0.000 0.695 0.304
E63.8 Other specified nutritional deficiencies
0.000 0.704 0.296
E63.1 Imbalance of constituents of food intake
0.000 0.704 0.296
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.704 0.296
L40-L45 Papulosquamous disorders
0.291 0.707 0.002
E53 Deficiency of other B group vitamins
0.000 0.707 0.293
E56.1 Deficiency of vitamin K
0.000 0.713 0.287
E11.9 Without complications
0.000 0.714 0.286
E11.5 With peripheral circulatory complications
0.000 0.730 0.270
E63.9 Nutritional deficiency, unspecified
0.000 0.734 0.266
E67 Other hyperalimentation
0.000 0.738 0.262
E68 Sequelae of hyperalimentation
0.000 0.738 0.262
E11.7 With multiple complications
0.000 0.745 0.255
E06.3 Autoimmune thyroiditis
0.000 0.750 0.250
E11.1 With ketoacidosis
0.000 0.754 0.246
E11.8 With unspecified complications
0.000 0.764 0.236
E11.6 With other specified complications
0.000 0.764 0.236
E20-E35 Disorders of other endocrine glands
0.000 0.773 0.227
L44 Other papulosquamous disorders
0.224 0.775 0.001
E11.2 With renal complications
0.000 0.786 0.214
E53.9 Vitamin B deficiency, unspecified
0.000 0.786 0.214
L41 Parapsoriasis
0.209 0.790 0.001
L45 Papulosquamous disorders in diseases classified elsewhere
0.209 0.790 0.001
E53.1 Pyridoxine deficiency
0.000 0.790 0.210
E53.0 Riboflavin deficiency
0.000 0.790 0.210
L42 Pityriasis rosea
0.207 0.792 0.001
E24 Cushing's syndrome
0.000 0.796 0.204
E65 Localised adiposity
0.000 0.812 0.188
E67.8 Other specified hyperalimentation
0.000 0.812 0.188
E67.3 Hypervitaminosis D
0.000 0.812 0.188
E67.2 Megavitamin-B6 syndrome
0.000 0.812 0.188
E67.1 Hypercarotenaemia
0.000 0.812 0.188
E67.0 Hypervitaminosis A
0.000 0.812 0.188
E29 Testicular dysfunction
0.000 0.817 0.183
E22 Hyperfunction of pituitary gland
0.000 0.819 0.181
E83 Disorders of mineral metabolism
0.178 0.821 0.001
E03.9 Hypothyroidism, unspecified
0.000 0.822 0.178
L44.0 Pityriasis rubra pilaris
0.175 0.824 0.001
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.829 0.171
E24.0 Pituitary-dependent Cushing's disease
0.000 0.830 0.170
E24.9 Cushing's syndrome, unspecified
0.000 0.832 0.168
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.837 0.163
E32 Diseases of thymus
0.000 0.837 0.163
E30 Disorders of puberty, not elsewhere classified
0.000 0.837 0.163
E25 Adrenogenital disorders
0.000 0.837 0.163
L44.9 Papulosquamous disorder, unspecified
0.161 0.838 0.001
L44.8 Other specified papulosquamous disorders
0.161 0.838 0.001
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.161 0.838 0.001
L44.3 Lichen ruber moniliformis
0.161 0.838 0.001
L44.2 Lichen striatus
0.161 0.838 0.001
L44.1 Lichen nitidus
0.161 0.838 0.001
E24.2 Drug-induced Cushing's syndrome
0.000 0.839 0.161
E22.1 Hyperprolactinaemia
0.000 0.842 0.158
E31 Polyglandular dysfunction
0.000 0.846 0.154
E29.1 Testicular hypofunction
0.000 0.848 0.152
L41.9 Parapsoriasis, unspecified
0.150 0.849 0.001
L41.8 Other parapsoriasis
0.150 0.849 0.001
L41.5 Retiform parapsoriasis
0.150 0.849 0.001
L41.4 Large plaque parapsoriasis
0.150 0.849 0.001
L41.3 Small plaque parapsoriasis
0.150 0.849 0.001
L41.2 Lymphomatoid papulosis
0.150 0.849 0.001
L41.1 Pityriasis lichenoides chronica
0.150 0.849 0.001
L41.0 Pityriasis lichenoides et varioliformis acuta
0.150 0.849 0.001
E26 Hyperaldosteronism
0.000 0.853 0.147
E24.8 Other Cushing's syndrome
0.000 0.853 0.146
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.853 0.146
E24.3 Ectopic ACTH syndrome
0.000 0.853 0.146
E24.1 Nelson's syndrome
0.000 0.853 0.146
E83.3 Disorders of phosphorus metabolism
0.145 0.854 0.000
E20 Hypoparathyroidism
0.000 0.855 0.145
E22.0 Acromegaly and pituitary gigantism
0.000 0.863 0.137
E23 Hypofunction and other disorders of pituitary gland
0.000 0.866 0.134
E83.9 Disorder of mineral metabolism, unspecified
0.132 0.867 0.001
E29.9 Testicular dysfunction, unspecified
0.000 0.868 0.131
E29.8 Other testicular dysfunction
0.000 0.868 0.131
E29.0 Testicular hyperfunction
0.000 0.868 0.131
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.870 0.130
E22.8 Other hyperfunction of pituitary gland
0.000 0.870 0.130
E83.8 Other disorders of mineral metabolism
0.128 0.871 0.001
E83.2 Disorders of zinc metabolism
0.128 0.871 0.001
E83.0 Disorders of copper metabolism
0.128 0.871 0.001
M45 Ankylosing spondylitis
0.000 0.873 0.127
E34 Other endocrine disorders
0.000 0.879 0.121
E25.9 Adrenogenital disorder, unspecified
0.000 0.883 0.117
E25.8 Other adrenogenital disorders
0.000 0.883 0.117
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.883 0.117
E30.9 Disorder of puberty, unspecified
0.000 0.883 0.117
E30.8 Other disorders of puberty
0.000 0.883 0.117
E30.1 Precocious puberty
0.000 0.883 0.117
E30.0 Delayed puberty
0.000 0.883 0.117
E32.9 Disease of thymus, unspecified
0.000 0.883 0.117
E32.8 Other diseases of thymus
0.000 0.883 0.117
E32.1 Abscess of thymus
0.000 0.883 0.117
E32.0 Persistent hyperplasia of thymus
0.000 0.883 0.117
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.883 0.117
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.883 0.117
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.883 0.117
L43 Lichen planus
0.106 0.886 0.008
E31.9 Polyglandular dysfunction, unspecified
0.000 0.889 0.110
E31.8 Other polyglandular dysfunction
0.000 0.889 0.110
E31.1 Polyglandular hyperfunction
0.000 0.889 0.110
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.890 0.110
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.891 0.109
E26.9 Hyperaldosteronism, unspecified
0.000 0.894 0.106
E26.8 Other hyperaldosteronism
0.000 0.894 0.106
E26.1 Secondary hyperaldosteronism
0.000 0.894 0.106
E28 Ovarian dysfunction
0.000 0.894 0.106
E66 Obesity
0.000 0.896 0.104
E20.8 Other hypoparathyroidism
0.000 0.896 0.104
E20.1 Pseudohypoparathyroidism
0.000 0.896 0.104
E20.0 Idiopathic hypoparathyroidism
0.000 0.896 0.104
E31.0 Autoimmune polyglandular failure
0.000 0.898 0.102
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.903 0.097
E23.0 Hypopituitarism
0.000 0.903 0.097
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.903 0.096
E23.1 Drug-induced hypopituitarism
0.000 0.903 0.096
E23.7 Disorder of pituitary gland, unspecified
0.000 0.905 0.095
E23.2 Diabetes insipidus
0.000 0.908 0.092
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.908 0.091
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.908 0.091
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.908 0.091
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.908 0.091
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.908 0.091
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.908 0.091
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.908 0.091
E34.8 Other specified endocrine disorders
0.000 0.909 0.091
E26.0 Primary hyperaldosteronism
0.000 0.909 0.090
E34.5 Androgen resistance syndrome
0.000 0.913 0.087
E34.4 Constitutional tall stature
0.000 0.913 0.087
E34.3 Short stature, not elsewhere classified
0.000 0.913 0.087
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.913 0.087
E34.1 Other hypersecretion of intestinal hormones
0.000 0.913 0.087
E20.9 Hypoparathyroidism, unspecified
0.000 0.914 0.086
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.916 0.084
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.917 0.083
L43.3 Subacute (active) lichen planus
0.076 0.918 0.006
L43.2 Lichenoid drug reaction
0.076 0.918 0.006
L43.1 Bullous lichen planus
0.076 0.918 0.006
L43.0 Hypertrophic lichen planus
0.076 0.918 0.006
J45 Asthma
0.000 0.920 0.080
E66.0 Obesity due to excess calories
0.000 0.923 0.077
E23.6 Other disorders of pituitary gland
0.000 0.923 0.077
E28.9 Ovarian dysfunction, unspecified
0.000 0.924 0.076
E28.8 Other ovarian dysfunction
0.000 0.924 0.076
E28.1 Androgen excess
0.000 0.924 0.076
E28.0 Oestrogen excess
0.000 0.924 0.076
E66.1 Drug-induced obesity
0.000 0.925 0.075
L43.8 Other lichen planus
0.067 0.927 0.006
E83.5 Disorders of calcium metabolism
0.073 0.927 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.930 0.070
E11.4 With neurological complications
0.000 0.931 0.068
E34.0 Carcinoid syndrome
0.000 0.932 0.067
E34.9 Endocrine disorder, unspecified
0.000 0.933 0.067
E28.3 Primary ovarian failure
0.000 0.937 0.062
E21.4 Other specified disorders of parathyroid gland
0.000 0.939 0.061
E21.2 Other hyperparathyroidism
0.000 0.939 0.061
J45.1 Nonallergic asthma
0.000 0.943 0.057
J45.8 Mixed asthma
0.000 0.944 0.056
E53.8 Deficiency of other specified B group vitamins
0.000 0.951 0.048
E04 Other non-toxic goitre
0.001 0.952 0.047
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.952 0.048
E27 Other disorders of adrenal gland
0.000 0.953 0.047
E28.2 Polycystic ovarian syndrome
0.000 0.954 0.046
K90-K93 Other diseases of the digestive system
0.000 0.959 0.041
I12.0 Hypertensive renal disease with renal failure
0.000 0.959 0.041
E11.3 With ophthalmic complications
0.000 0.960 0.040
I12.9 Hypertensive renal disease without renal failure
0.000 0.961 0.039
I12 Hypertensive renal disease
0.000 0.962 0.038
E04.8 Other specified non-toxic goitre
0.001 0.965 0.034
E21.3 Hyperparathyroidism, unspecified
0.000 0.965 0.035
E27.5 Adrenomedullary hyperfunction
0.000 0.966 0.034
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.966 0.034
E27.0 Other adrenocortical overactivity
0.000 0.966 0.034
E21.0 Primary hyperparathyroidism
0.000 0.967 0.033
E27.9 Disorder of adrenal gland, unspecified
0.000 0.967 0.033
K74.3 Primary biliary cirrhosis
0.000 0.968 0.032
E27.8 Other specified disorders of adrenal gland
0.000 0.969 0.030
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.970 0.030
E70-E90 Metabolic disorders
0.023 0.972 0.004
E83.4 Disorders of magnesium metabolism
0.026 0.973 0.001
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.976 0.024
Chapter XII Diseases of the skin and subcutaneous tissue
0.023 0.977 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.977 0.022
E66.8 Other obesity
0.000 0.977 0.023
M75.0 Adhesive capsulitis of shoulder
0.000 0.977 0.023
E88 Other metabolic disorders
0.021 0.977 0.001
L30 Other dermatitis
0.023 0.977 0.000
L20-L30 Dermatitis and eczema
0.023 0.977 0.000
L30.9 Dermatitis, unspecified
0.023 0.977 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.978 0.021
K93.1 Megacolon in Chagas' disease
0.000 0.978 0.021
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.978 0.021
E27.1 Primary adrenocortical insufficiency
0.000 0.979 0.021
L20 Atopic dermatitis
0.021 0.979 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.020 0.979 0.001
L43.9 Lichen planus, unspecified
0.004 0.980 0.016
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.017 0.980 0.003
L21 Seborrhoeic dermatitis
0.020 0.980 0.000
E85 Amyloidosis
0.018 0.980 0.002
E79 Disorders of purine and pyrimidine metabolism
0.017 0.980 0.003
E77 Disorders of glycoprotein metabolism
0.017 0.980 0.003
E76 Disorders of glycosaminoglycan metabolism
0.017 0.980 0.003
E72 Other disorders of amino-acid metabolism
0.017 0.980 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.017 0.980 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.017 0.980 0.003
E84 Cystic fibrosis
0.017 0.980 0.003
E70 Disorders of aromatic amino-acid metabolism
0.017 0.980 0.003
E73 Lactose intolerance
0.017 0.980 0.003
E88.1 Lipodystrophy, not elsewhere classified
0.019 0.980 0.001
E74 Other disorders of carbohydrate metabolism
0.017 0.980 0.003
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.019 0.981 0.000
J33.9 Nasal polyp, unspecified
0.000 0.981 0.019
L30.1 Dyshidrosis [pompholyx]
0.019 0.981 0.000
L21.9 Seborrhoeic dermatitis, unspecified
0.019 0.981 0.000
L30.8 Other specified dermatitis
0.019 0.981 0.000
E27.2 Addisonian crisis
0.001 0.981 0.018
K74 Fibrosis and cirrhosis of liver
0.000 0.982 0.018
L23 Allergic contact dermatitis
0.018 0.982 0.000
L20.9 Atopic dermatitis, unspecified
0.018 0.982 0.000
J45.0 Predominantly allergic asthma
0.000 0.982 0.018
L20.8 Other atopic dermatitis
0.018 0.982 0.000
K74.5 Biliary cirrhosis, unspecified
0.000 0.982 0.018
E80.1 Porphyria cutanea tarda
0.016 0.983 0.001
E88.9 Metabolic disorder, unspecified
0.016 0.983 0.001
E88.3 Tumour lysis syndrome
0.016 0.983 0.001
L30.5 Pityriasis alba
0.016 0.983 0.000
L30.2 Cutaneous autosensitisation
0.016 0.983 0.000
L30.0 Nummular dermatitis
0.016 0.983 0.000
L24 Irritant contact dermatitis
0.016 0.984 0.000
L26 Exfoliative dermatitis
0.016 0.984 0.000
L22 Diaper [napkin] dermatitis
0.016 0.984 0.000
L10-L14 Bullous disorders
0.016 0.984 0.000
E80.6 Other disorders of bilirubin metabolism
0.016 0.984 0.001
E80.2 Other porphyria
0.015 0.984 0.001
E85.3 Secondary systemic amyloidosis
0.015 0.984 0.001
E88.2 Lipomatosis, not elsewhere classified
0.015 0.984 0.001
E88.8 Other specified metabolic disorders
0.014 0.985 0.001
L25 Unspecified contact dermatitis
0.015 0.985 0.000
L20.0 Besnier's prurigo
0.015 0.985 0.000
L23.5 Allergic contact dermatitis due to other chemical products
0.015 0.985 0.000
E75.2 Other sphingolipidosis
0.013 0.985 0.002
L30.4 Erythema intertrigo
0.015 0.985 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.014 0.985 0.001
E80.5 Crigler-Najjar syndrome
0.014 0.985 0.001
E80.3 Defects of catalase and peroxydase
0.014 0.985 0.001
E80.0 Hereditary erythropoietic porphyria
0.014 0.985 0.001
E85.4 Organ-limited amyloidosis
0.014 0.985 0.001
L30.3 Infective dermatitis
0.015 0.985 0.000
E74.0 Glycogen storage disease
0.013 0.985 0.002
E75.6 Lipid storage disorder, unspecified
0.013 0.985 0.002
E75.5 Other lipid storage disorders
0.013 0.985 0.002
E75.4 Neuronal ceroid lipofuscinosis
0.013 0.985 0.002
E75.3 Sphingolipidosis, unspecified
0.013 0.985 0.002
E75.1 Other gangliosidosis
0.013 0.985 0.002
E75.0 GM2 gangliosidosis
0.013 0.985 0.002
L21.8 Other seborrhoeic dermatitis
0.015 0.985 0.000
L21.1 Seborrhoeic infantile dermatitis
0.015 0.985 0.000
L21.0 Seborrhoea capitis
0.015 0.985 0.000
E85.8 Other amyloidosis
0.013 0.985 0.002
E85.2 Heredofamilial amyloidosis, unspecified
0.013 0.985 0.002
E85.1 Neuropathic heredofamilial amyloidosis
0.013 0.985 0.002
E85.0 Nonneuropathic heredofamilial amyloidosis
0.013 0.985 0.002
E71.3 Disorders of fatty-acid metabolism
0.012 0.985 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.012 0.985 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.012 0.985 0.002
E71.0 Maple-syrup-urine disease
0.012 0.985 0.002
E72.9 Disorder of amino-acid metabolism, unspecified
0.012 0.985 0.002
E72.8 Other specified disorders of amino-acid metabolism
0.012 0.985 0.002
E72.5 Disorders of glycine metabolism
0.012 0.985 0.002
E72.4 Disorders of ornithine metabolism
0.012 0.985 0.002
E72.3 Disorders of lysine and hydroxylysine metabolism
0.012 0.985 0.002
E72.2 Disorders of urea cycle metabolism
0.012 0.985 0.002
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.012 0.985 0.002
E72.0 Disorders of amino-acid transport
0.012 0.985 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.012 0.985 0.002
E76.8 Other disorders of glucosaminoglycan metabolism
0.012 0.985 0.002
E76.3 Mucopolysaccharidosis, unspecified
0.012 0.985 0.002
E76.2 Other mucopolysaccharidoses
0.012 0.985 0.002
E76.1 Mucopolysaccharidosis, type II
0.012 0.985 0.002
E76.0 Mucopolysaccharidosis, type I
0.012 0.985 0.002
E77.9 Disorder of glycoprotein metabolism, unspecified
0.012 0.985 0.002
E77.8 Other disorders of glycoprotein metabolism
0.012 0.985 0.002
E77.1 Defects in glycoprotein degradation
0.012 0.985 0.002
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.012 0.985 0.002
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.012 0.985 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.012 0.985 0.002
E79.1 Lesch-Nyhan syndrome
0.012 0.985 0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.012 0.985 0.002
E84.8 Cystic fibrosis with other manifestations
0.012 0.985 0.002
E84.1 Cystic fibrosis with intestinal manifestations
0.012 0.985 0.002
E84.0 Cystic fibrosis with pulmonary manifestations
0.012 0.985 0.002
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.012 0.986 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.012 0.986 0.002
E70.2 Disorders of tyrosine metabolism
0.012 0.986 0.002
E70.1 Other hyperphenylalaninaemias
0.012 0.986 0.002
E70.0 Classical phenylketonuria
0.012 0.986 0.002
E73.8 Other lactose intolerance
0.012 0.986 0.002
E73.1 Secondary lactase deficiency
0.012 0.986 0.002
E73.0 Congenital lactase deficiency
0.012 0.986 0.002
E84.9 Cystic fibrosis, unspecified
0.012 0.986 0.002
E74.9 Disorder of carbohydrate metabolism, unspecified
0.012 0.986 0.002
E74.8 Other specified disorders of carbohydrate metabolism
0.012 0.986 0.002
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.012 0.986 0.002
E74.2 Disorders of galactose metabolism
0.012 0.986 0.002
E74.1 Disorders of fructose metabolism
0.012 0.986 0.002
K74.6 Other and unspecified cirrhosis of liver
0.000 0.986 0.014
E70.3 Albinism
0.012 0.986 0.002
E73.9 Lactose intolerance, unspecified
0.013 0.986 0.001
L50-L54 Urticaria and erythema
0.014 0.986 0.000
L23.1 Allergic contact dermatitis due to adhesives
0.014 0.986 0.000
L60-L75 Disorders of skin appendages
0.014 0.986 0.000
K74.4 Secondary biliary cirrhosis
0.000 0.986 0.013
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.986 0.013
K74.1 Hepatic sclerosis
0.000 0.986 0.013
L11 Other acantholytic disorders
0.013 0.986 0.000
L23.8 Allergic contact dermatitis due to other agents
0.013 0.987 0.000
L23.7 Allergic contact dermatitis due to plants, except food
0.013 0.987 0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin
0.013 0.987 0.000
L23.4 Allergic contact dermatitis due to dyes
0.013 0.987 0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin
0.013 0.987 0.000
L23.2 Allergic contact dermatitis due to cosmetics
0.013 0.987 0.000
L23.0 Allergic contact dermatitis due to metals
0.013 0.987 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.011 0.987 0.002
E85.9 Amyloidosis, unspecified
0.011 0.987 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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