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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3095250
log Bayes Factor = 74.123
Chromosome 6   position 31,208,340  (GRCh37) Explore rs3095250 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.003 0.997
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
E11 Non-insulin-dependent diabetes mellitus
0.000 0.005 0.995
E11.9 Without complications
0.000 0.007 0.993
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.013 0.987
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.014 0.986
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.027 0.973
E14 Unspecified diabetes mellitus
0.000 0.027 0.973
M45 Ankylosing spondylitis
0.963 0.037 0.000
E11.1 With ketoacidosis
0.000 0.060 0.940
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.939 0.061 0.000
E11.0 With coma
0.000 0.089 0.911
L40 Psoriasis
0.000 0.103 0.897
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.110 0.890
K90 Intestinal malabsorption
0.000 0.113 0.887
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.115 0.885
E14.9 Without complications
0.000 0.116 0.884
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.124 0.876
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.127 0.873
E10.5 With peripheral circulatory complications
0.000 0.128 0.872
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.153 0.847
L40.0 Psoriasis vulgaris
0.000 0.154 0.846
E10.0 With coma
0.000 0.157 0.843
E10.8 With unspecified complications
0.000 0.159 0.841
E16 Other disorders of pancreatic internal secretion
0.000 0.171 0.829
K90.9 Intestinal malabsorption, unspecified
0.000 0.177 0.823
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.178 0.822
E05.9 Thyrotoxicosis, unspecified
0.000 0.178 0.822
E00-E07 Disorders of thyroid gland
0.000 0.182 0.818
E20-E35 Disorders of other endocrine glands
0.000 0.185 0.815
E11.5 With peripheral circulatory complications
0.000 0.185 0.815
E16.2 Hypoglycaemia, unspecified
0.000 0.188 0.812
M45.X6 Ankylosing spondylitis (Lumbar region)
0.807 0.193 0.000
E14.1 With ketoacidosis
0.000 0.196 0.804
E14.2 Withrenal complications
0.000 0.210 0.790
E13 Other specified diabetes mellitus
0.000 0.214 0.786
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.217 0.783
E14.8 With unspecified complications
0.000 0.218 0.782
E14.3 With ophthalmic complications
0.000 0.220 0.780
E14.6 With other specified complications
0.000 0.223 0.777
M45.X2 Ankylosing spondylitis (Cervical region)
0.776 0.224 0.000
L40.5 Arthropathic psoriasis
0.000 0.225 0.775
E10.2 With renal complications
0.000 0.227 0.773
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.234 0.766
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.239 0.761
E10.4 With neurological complications
0.000 0.255 0.745
E10.6 With other specified complications
0.000 0.259 0.741
E22 Hyperfunction of pituitary gland
0.000 0.271 0.729
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.287 0.713
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.296 0.704
M06 Other rheumatoid arthritis
0.000 0.300 0.700
E14.7 With multiple complications
0.000 0.302 0.698
E14.0 With coma
0.000 0.302 0.698
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.303 0.697
E16.1 Other hypoglycaemia
0.000 0.309 0.691
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.691 0.309 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.691 0.309 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.691 0.309 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.691 0.309 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.691 0.309 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.691 0.309 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.323 0.677
M06.3 Rheumatoid nodule
0.000 0.326 0.674
E14.5 With peripheral circulatory complications
0.000 0.328 0.672
L40.8 Other psoriasis
0.000 0.337 0.663
E13.9 Without complications
0.000 0.338 0.662
L40.4 Guttate psoriasis
0.000 0.339 0.660
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.340 0.660
E10.7 With multiple complications
0.000 0.345 0.655
E21.3 Hyperparathyroidism, unspecified
0.000 0.345 0.655
K90.8 Other intestinal malabsorption
0.000 0.349 0.651
L40.1 Generalised pustular psoriasis
0.000 0.356 0.644
L40.2 Acrodermatitis continua
0.000 0.357 0.643
E28 Ovarian dysfunction
0.000 0.359 0.641
K90.3 Pancreatic steatorrhoea
0.000 0.364 0.636
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.364 0.636
K90.1 Tropical sprue
0.000 0.364 0.636
E25 Adrenogenital disorders
0.000 0.366 0.634
E23 Hypofunction and other disorders of pituitary gland
0.000 0.371 0.629
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.389 0.611
E21.0 Primary hyperparathyroidism
0.000 0.390 0.610
E40-E46 Malnutrition
0.000 0.390 0.609
E15 Nondiabetic hypoglycaemic coma
0.000 0.393 0.607
E14.4 With neurological complications
0.000 0.402 0.598
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.406 0.594
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.406 0.594
E16.4 Abnormal secretion of gastrin
0.000 0.406 0.594
E16.3 Increased secretion of glucagon
0.000 0.406 0.594
E05.5 Thyroid crisis or storm
0.000 0.411 0.589
E05.4 Thyrotoxicosis factitia
0.000 0.411 0.589
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.411 0.589
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.411 0.589
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.413 0.587
E00 Congenital iodine-deficiency syndrome
0.000 0.413 0.587
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.416 0.584
E32 Diseases of thymus
0.000 0.416 0.584
E30 Disorders of puberty, not elsewhere classified
0.000 0.416 0.584
J45.9 Asthma, unspecified
0.000 0.418 0.582
E31 Polyglandular dysfunction
0.000 0.428 0.572
E20 Hypoparathyroidism
0.000 0.430 0.570
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.433 0.567
E05.8 Other thyrotoxicosis
0.000 0.433 0.567
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.434 0.566
L40.3 Pustulosis palmaris et plantaris
0.000 0.435 0.565
E13.8 With unspecified complications
0.000 0.437 0.563
E13.7 With multiple complications
0.000 0.437 0.563
E13.6 With other specified complications
0.000 0.437 0.563
E13.5 With peripheral circulatory complications
0.000 0.437 0.563
E13.4 With neurological complications
0.000 0.437 0.563
E13.2 With renal complications
0.000 0.437 0.563
E13.1 With ketoacidosis
0.000 0.437 0.563
E13.0 With coma
0.000 0.437 0.563
E29 Testicular dysfunction
0.000 0.439 0.561
E28.2 Polycystic ovarian syndrome
0.000 0.439 0.561
E34 Other endocrine disorders
0.000 0.446 0.554
E22.1 Hyperprolactinaemia
0.000 0.452 0.548
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.452 0.548
E21.4 Other specified disorders of parathyroid gland
0.000 0.454 0.545
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.455 0.545
M06.34 Rheumatoid nodule (Hand)
0.000 0.457 0.543
E24 Cushing's syndrome
0.000 0.473 0.527
M06.4 Inflammatory polyarthropathy
0.000 0.473 0.527
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.477 0.523
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.477 0.522
E22.8 Other hyperfunction of pituitary gland
0.000 0.477 0.522
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.478 0.522
E27 Other disorders of adrenal gland
0.000 0.483 0.517
E21.2 Other hyperparathyroidism
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E13.3 With ophthalmic complications
0.000 0.490 0.510
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.496 0.504
M06.2 Rheumatoid bursitis
0.000 0.498 0.502
M06.1 Adult-onset Still's disease
0.000 0.498 0.502
E11.6 With other specified complications
0.000 0.498 0.501
E23.7 Disorder of pituitary gland, unspecified
0.000 0.511 0.489
E23.6 Other disorders of pituitary gland
0.000 0.515 0.485
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.517 0.483
M06.38 Rheumatoid nodule (Other)
0.000 0.517 0.483
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.517 0.483
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.517 0.483
M06.33 Rheumatoid nodule (Forearm)
0.000 0.517 0.483
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.517 0.483
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.518 0.482
K51.9 Ulcerative colitis, unspecified
0.478 0.522 0.000
E23.2 Diabetes insipidus
0.000 0.523 0.477
E11.8 With unspecified complications
0.000 0.529 0.470
E34.9 Endocrine disorder, unspecified
0.000 0.534 0.466
E11.4 With neurological complications
0.000 0.536 0.464
M06.8 Other specified rheumatoid arthritis
0.000 0.539 0.460
E28.9 Ovarian dysfunction, unspecified
0.000 0.540 0.459
E28.8 Other ovarian dysfunction
0.000 0.540 0.459
E28.1 Androgen excess
0.000 0.540 0.459
E28.0 Oestrogen excess
0.000 0.540 0.459
E25.9 Adrenogenital disorder, unspecified
0.000 0.546 0.454
E25.8 Other adrenogenital disorders
0.000 0.546 0.454
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.549 0.451
E23.1 Drug-induced hypopituitarism
0.000 0.549 0.451
E22.0 Acromegaly and pituitary gigantism
0.000 0.554 0.446
E27.9 Disorder of adrenal gland, unspecified
0.000 0.557 0.443
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.563 0.437
E45 Retarded development following protein-energy malnutrition
0.000 0.563 0.437
E43 Unspecified severe protein-energy malnutrition
0.000 0.563 0.437
E42 Marasmic kwashiorkor
0.000 0.563 0.437
E41 Nutritional marasmus
0.000 0.563 0.437
E40 Kwashiorkor
0.000 0.563 0.437
K51 Ulcerative colitis
0.431 0.569 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.571 0.429
K51.4 Pseudopolyposis of colon
0.426 0.574 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.579 0.421
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.579 0.421
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.579 0.421
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.579 0.421
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.579 0.421
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.579 0.421
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.579 0.421
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.579 0.421
E46 Unspecified protein-energy malnutrition
0.000 0.579 0.421
E27.1 Primary adrenocortical insufficiency
0.000 0.581 0.419
E30.9 Disorder of puberty, unspecified
0.000 0.581 0.419
E30.8 Other disorders of puberty
0.000 0.581 0.419
E30.1 Precocious puberty
0.000 0.581 0.419
E30.0 Delayed puberty
0.000 0.581 0.419
E32.9 Disease of thymus, unspecified
0.000 0.581 0.419
E32.8 Other diseases of thymus
0.000 0.581 0.419
E32.1 Abscess of thymus
0.000 0.581 0.419
E32.0 Persistent hyperplasia of thymus
0.000 0.581 0.419
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.581 0.419
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.581 0.419
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.581 0.419
E24.0 Pituitary-dependent Cushing's disease
0.000 0.590 0.410
E31.9 Polyglandular dysfunction, unspecified
0.000 0.590 0.410
E31.8 Other polyglandular dysfunction
0.000 0.590 0.410
E31.1 Polyglandular hyperfunction
0.000 0.590 0.410
E20.8 Other hypoparathyroidism
0.000 0.591 0.409
E20.1 Pseudohypoparathyroidism
0.000 0.591 0.409
E20.0 Idiopathic hypoparathyroidism
0.000 0.591 0.409
E29.9 Testicular dysfunction, unspecified
0.000 0.597 0.402
E29.8 Other testicular dysfunction
0.000 0.597 0.402
E29.0 Testicular hyperfunction
0.000 0.597 0.402
E03 Other hypothyroidism
0.000 0.598 0.402
E31.0 Autoimmune polyglandular failure
0.000 0.602 0.398
E34.5 Androgen resistance syndrome
0.000 0.603 0.397
E34.4 Constitutional tall stature
0.000 0.603 0.397
E34.3 Short stature, not elsewhere classified
0.000 0.603 0.397
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.603 0.397
E34.1 Other hypersecretion of intestinal hormones
0.000 0.603 0.397
E20.9 Hypoparathyroidism, unspecified
0.000 0.605 0.395
E06 Thyroiditis
0.000 0.608 0.392
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.615 0.385
E23.0 Hypopituitarism
0.000 0.618 0.382
E29.1 Testicular hypofunction
0.000 0.621 0.379
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.622 0.378
E24.3 Ectopic ACTH syndrome
0.000 0.622 0.378
E24.1 Nelson's syndrome
0.000 0.622 0.378
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.622 0.378
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.622 0.378
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.622 0.378
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.622 0.378
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.622 0.378
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.622 0.378
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.622 0.378
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.622 0.378
E24.2 Drug-induced Cushing's syndrome
0.000 0.622 0.378
E26 Hyperaldosteronism
0.001 0.625 0.375
K51.3 Ulcerative (chronic) rectosigmoiditis
0.373 0.627 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.629 0.370
E27.0 Other adrenocortical overactivity
0.000 0.629 0.370
E11.2 With renal complications
0.000 0.638 0.361
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.640 0.360
M06.18 Adult-onset Still's disease (Other)
0.000 0.640 0.360
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.640 0.360
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.640 0.360
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.640 0.360
M06.14 Adult-onset Still's disease (Hand)
0.000 0.640 0.360
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.640 0.360
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.640 0.360
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.640 0.360
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.640 0.360
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.640 0.360
M06.28 Rheumatoid bursitis (Other)
0.000 0.640 0.360
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.640 0.360
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.640 0.360
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.640 0.360
M06.24 Rheumatoid bursitis (Hand)
0.000 0.640 0.360
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.640 0.360
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.640 0.360
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.640 0.360
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.640 0.360
E28.3 Primary ovarian failure
0.000 0.641 0.359
E34.0 Carcinoid syndrome
0.000 0.660 0.340
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.662 0.338
E24.9 Cushing's syndrome, unspecified
0.000 0.664 0.336
K51.5 Mucosal proctocolitis
0.332 0.668 0.000
E27.2 Addisonian crisis
0.000 0.669 0.331
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.670 0.330
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.670 0.330
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.670 0.330
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.670 0.330
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.670 0.330
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.670 0.330
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.670 0.330
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.670 0.330
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.670 0.330
K51.8 Other ulcerative colitis
0.329 0.671 0.000
E07 Other disorders of thyroid
0.000 0.675 0.325
E24.8 Other Cushing's syndrome
0.000 0.676 0.323
E44.1 Mild protein-energy malnutrition
0.000 0.686 0.313
E44.0 Moderate protein-energy malnutrition
0.000 0.686 0.313
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.689 0.310
E34.8 Other specified endocrine disorders
0.000 0.691 0.309
E03.1 Congenital hypothyroidism without goitre
0.000 0.695 0.305
E06.5 Other chronic thyroiditis
0.000 0.703 0.297
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.001 0.711 0.288
E03.5 Myxoedema coma
0.000 0.711 0.288
E03.4 Atrophy of thyroid (acquired)
0.000 0.711 0.288
E03.3 Postinfectious hypothyroidism
0.000 0.711 0.288
E03.8 Other specified hypothyroidism
0.000 0.713 0.287
E06.1 Subacute thyroiditis
0.000 0.716 0.284
E06.4 Drug-induced thyroiditis
0.000 0.719 0.281
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.719 0.281
E06.0 Acute thyroiditis
0.000 0.719 0.281
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.720 0.280
E26.8 Other hyperaldosteronism
0.001 0.731 0.269
E26.1 Secondary hyperaldosteronism
0.001 0.731 0.269
E50-E64 Other nutritional deficiencies
0.000 0.744 0.255
E11.3 With ophthalmic complications
0.000 0.745 0.255
E65-E68 Obesity and other hyperalimentation
0.001 0.746 0.252
K51.1 Ulcerative (chronic) ileocolitis
0.247 0.752 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.758 0.242
E07.1 Dyshormogenetic goitre
0.000 0.766 0.233
E07.0 Hypersecretion of calcitonin
0.000 0.766 0.233
K51.2 Ulcerative (chronic) proctitis
0.225 0.775 0.000
E06.9 Thyroiditis, unspecified
0.000 0.775 0.224
E27.8 Other specified disorders of adrenal gland
0.000 0.777 0.223
J45 Asthma
0.000 0.780 0.220
M45-M49 Spondylopathies
0.213 0.787 0.000
M05-M14 Inflammatory polyarthropathies
0.001 0.787 0.212
L40-L45 Papulosquamous disorders
0.000 0.790 0.210
E26.9 Hyperaldosteronism, unspecified
0.001 0.791 0.209
K51.0 Ulcerative (chronic) enterocolitis
0.208 0.791 0.000
M05 Seropositive rheumatoid arthritis
0.001 0.795 0.205
G35 Multiple sclerosis
0.204 0.796 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.799 0.201
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.806 0.194
M48 Other spondylopathies
0.193 0.807 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.191 0.809 0.000
E07.8 Other specified disorders of thyroid
0.000 0.812 0.188
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.817 0.183
E63 Other nutritional deficiencies
0.000 0.817 0.183
E50 Vitamin A deficiency
0.000 0.817 0.183
E60 Dietary zinc deficiency
0.000 0.817 0.183
E59 Dietary selenium deficiency
0.000 0.817 0.183
E54 Ascorbic acid deficiency
0.000 0.817 0.183
E52 Niacin deficiency [pellagra]
0.000 0.817 0.183
E67 Other hyperalimentation
0.001 0.818 0.181
E68 Sequelae of hyperalimentation
0.001 0.818 0.181
E55 Vitamin D deficiency
0.000 0.819 0.181
J45.1 Nonallergic asthma
0.000 0.819 0.181
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.181 0.819 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.821 0.179
E56 Other vitamin deficiencies
0.000 0.823 0.177
E70-E90 Metabolic disorders
0.000 0.824 0.176
E51 Thiamine deficiency
0.000 0.824 0.176
E26.0 Primary hyperaldosteronism
0.001 0.826 0.173
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.170 0.830 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.832 0.168
J45.8 Mixed asthma
0.000 0.833 0.167
M07 Psoriatic and enteropathic arthropathies
0.001 0.833 0.166
E78.2 Mixed hyperlipidaemia
0.000 0.836 0.164
M12 Other specific arthropathies
0.001 0.837 0.162
E88 Other metabolic disorders
0.000 0.838 0.162
M05.8 Other seropositive rheumatoid arthritis
0.000 0.839 0.160
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.840 0.160
E58 Dietary calcium deficiency
0.000 0.841 0.159
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.154 0.846 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.001 0.847 0.152
E06.3 Autoimmune thyroiditis
0.000 0.849 0.150
L44 Other papulosquamous disorders
0.000 0.849 0.150
L41 Parapsoriasis
0.000 0.849 0.150
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.849 0.150
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.852 0.148
J33.0 Polyp of nasal cavity
0.000 0.852 0.148
M08 Juvenile arthritis
0.001 0.852 0.147
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.853 0.147
M05.1 Rheumatoid lung disease
0.001 0.853 0.147
M05.0 Felty's syndrome
0.001 0.853 0.147
E78.8 Other disorders of lipoprotein metabolism
0.000 0.854 0.146
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.855 0.144
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.855 0.144
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.855 0.144
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.855 0.144
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.143 0.857 0.000
E04 Other non-toxic goitre
0.000 0.858 0.142
E83.1 Disorders of iron metabolism
0.140 0.860 0.000
J33 Nasal polyp
0.000 0.860 0.140
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.861 0.139
L42 Pityriasis rosea
0.000 0.861 0.139
M07.3 Other psoriatic arthropathies
0.000 0.861 0.138
M48.4 Fatigue fracture of vertebra
0.138 0.861 0.000
M48.3 Traumatic spondylopathy
0.138 0.861 0.000
M48.2 Kissing spine
0.138 0.861 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.138 0.861 0.000
J33.9 Nasal polyp, unspecified
0.000 0.862 0.138
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.137 0.863 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.137 0.863 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.137 0.863 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.137 0.863 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.137 0.863 0.000
M48.9 Spondylopathy, unspecified
0.134 0.866 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.867 0.133
E79 Disorders of purine and pyrimidine metabolism
0.000 0.867 0.133
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.868 0.132
E50.9 Vitamin A deficiency, unspecified
0.000 0.868 0.131
E50.8 Other manifestations of vitamin A deficiency
0.000 0.868 0.131
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.868 0.131
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.868 0.131
E50.5 Vitamin A deficiency with night blindness
0.000 0.868 0.131
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.868 0.131
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.868 0.131
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.868 0.131
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.868 0.131
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.868 0.131
E63.9 Nutritional deficiency, unspecified
0.000 0.868 0.131
E63.8 Other specified nutritional deficiencies
0.000 0.868 0.131
E63.1 Imbalance of constituents of food intake
0.000 0.868 0.131
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.868 0.131
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.868 0.131
E64.8 Sequelae of other nutritional deficiencies
0.000 0.868 0.131
E64.3 Sequelae of rickets
0.000 0.868 0.131
E64.2 Sequelae of vitamin C deficiency
0.000 0.868 0.131
E64.1 Sequelae of vitamin A deficiency
0.000 0.868 0.131
E64.0 Sequelae of protein-energy malnutrition
0.000 0.868 0.131
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.868 0.131
E61 Deficiency of other nutrient elements
0.000 0.869 0.131
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.131 0.869 0.000
E67.8 Other specified hyperalimentation
0.001 0.869 0.130
E67.3 Hypervitaminosis D
0.001 0.869 0.130
E67.2 Megavitamin-B6 syndrome
0.001 0.869 0.130
E67.1 Hypercarotenaemia
0.001 0.869 0.130
E67.0 Hypervitaminosis A
0.001 0.869 0.130
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.869 0.131
E88.2 Lipomatosis, not elsewhere classified
0.000 0.870 0.130
E55.0 Rickets, active
0.000 0.870 0.130
M12.2 Villonodular synovitis (pigmented)
0.000 0.871 0.129
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.871 0.129
M46 Other inflammatory spondylopathies
0.129 0.871 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.873 0.127
E56.9 Vitamin deficiency, unspecified
0.000 0.873 0.127
E56.8 Deficiency of other vitamins
0.000 0.873 0.127
E56.0 Deficiency of vitamin E
0.000 0.873 0.127
E77 Disorders of glycoprotein metabolism
0.000 0.874 0.126
E76 Disorders of glycosaminoglycan metabolism
0.000 0.874 0.126
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.874 0.126
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.874 0.126
E51.9 Thiamine deficiency, unspecified
0.000 0.874 0.126
E51.8 Other manifestations of thiamine deficiency
0.000 0.874 0.126
E51.1 Beriberi
0.000 0.874 0.126
E70 Disorders of aromatic amino-acid metabolism
0.000 0.874 0.126
E78.4 Other hyperlipidaemia
0.000 0.874 0.126
M48.8 Other specified spondylopathies
0.125 0.875 0.000
E73 Lactose intolerance
0.000 0.875 0.125
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.877 0.123
M11 Other crystal arthropathies
0.001 0.877 0.122
M14 Arthropathies in other diseases classified elsewhere
0.001 0.877 0.122
E89.3 Postprocedural hypopituitarism
0.000 0.878 0.122
E88.9 Metabolic disorder, unspecified
0.000 0.878 0.122
E56.1 Deficiency of vitamin K
0.000 0.880 0.120
M07.5 Arthropathy in ulcerative colitis
0.001 0.880 0.119
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.880 0.119
M07.2 Psoriatic spondylitis
0.001 0.880 0.119
M07.1 Arthritis mutilans
0.001 0.880 0.119
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.880 0.119
E51.2 Wernicke's encephalopathy
0.000 0.881 0.119
G35-G37 Demyelinating diseases of the central nervous system
0.118 0.882 0.000
E72 Other disorders of amino-acid metabolism
0.000 0.882 0.118
M12.8 Other specific arthropathies, not elsewhere classified
0.001 0.883 0.117
M12.5 Traumatic arthropathy
0.001 0.883 0.117
M12.4 Intermittent hydrarthrosis
0.001 0.883 0.117
M12.1 Kaschin-Beck disease
0.001 0.883 0.117
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.001 0.883 0.117
J33.8 Other polyp of sinus
0.000 0.884 0.116
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.884 0.115
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.884 0.115
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.884 0.115
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.884 0.115
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.884 0.115
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.884 0.115
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.884 0.115
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.884 0.115
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.884 0.115
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.884 0.115
E88.8 Other specified metabolic disorders
0.000 0.884 0.115
E88.3 Tumour lysis syndrome
0.000 0.885 0.115
M12.3 Palindromic rheumatism
0.001 0.886 0.114
E85 Amyloidosis
0.000 0.886 0.114
E65 Localised adiposity
0.001 0.886 0.113
E78.6 Lipoprotein deficiency
0.000 0.886 0.114
M05.2 Rheumatoid vasculitis
0.001 0.886 0.113
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.887 0.113
M49 Spondylopathies in diseases classified elsewhere
0.112 0.887 0.001
M07.6 Other enteropathic arthropathies
0.001 0.889 0.110
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.001 0.890 0.109
M09.2 Juvenile arthritis in ulcerative colitis
0.001 0.890 0.109
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.001 0.890 0.109
M09.0 Juvenile arthritis in psoriasis
0.001 0.890 0.109
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.891 0.109
E78.3 Hyperchylomicronaemia
0.000 0.891 0.108
L41.9 Parapsoriasis, unspecified
0.000 0.892 0.108
L41.8 Other parapsoriasis
0.000 0.892 0.108
L41.5 Retiform parapsoriasis
0.000 0.892 0.108
L41.4 Large plaque parapsoriasis
0.000 0.892 0.108
L41.3 Small plaque parapsoriasis
0.000 0.892 0.108
L41.2 Lymphomatoid papulosis
0.000 0.892 0.108
L41.1 Pityriasis lichenoides chronica
0.000 0.892 0.108
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.892 0.108
L44.9 Papulosquamous disorder, unspecified
0.000 0.892 0.108
L44.8 Other specified papulosquamous disorders
0.000 0.892 0.108
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.892 0.108
L44.3 Lichen ruber moniliformis
0.000 0.892 0.108
L44.2 Lichen striatus
0.000 0.892 0.108
L44.1 Lichen nitidus
0.000 0.892 0.108
L44.0 Pityriasis rubra pilaris
0.000 0.892 0.108

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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