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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3095254
log Bayes Factor = 86.3712
Chromosome 6   position 31,221,668  (GRCh37) Explore rs3095254 on Ensembl!
Variant rs3095254 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E14.9 Without complications
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.004 0.996
G35 Multiple sclerosis
0.990 0.010 0.000
L40 Psoriasis
0.000 0.020 0.980
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.022 0.978
E10.4 With neurological complications
0.000 0.027 0.973
E11.1 With ketoacidosis
0.000 0.036 0.964
L40.5 Arthropathic psoriasis
0.000 0.042 0.958
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.054 0.946
E11.5 With peripheral circulatory complications
0.000 0.057 0.943
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.075 0.925
I10 Essential (primary) hypertension
0.000 0.076 0.924
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.092 0.908
E16.2 Hypoglycaemia, unspecified
0.000 0.093 0.907
E16 Other disorders of pancreatic internal secretion
0.000 0.093 0.907
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.093 0.907
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.103 0.897
E10.0 With coma
0.000 0.114 0.886
M06 Other rheumatoid arthritis
0.000 0.122 0.878
L40.0 Psoriasis vulgaris
0.000 0.123 0.877
E11.0 With coma
0.000 0.123 0.877
E14.3 With ophthalmic complications
0.000 0.125 0.875
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.128 0.872
E10.2 With renal complications
0.000 0.139 0.860
E11.4 With neurological complications
0.000 0.147 0.853
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.147 0.853
E11.3 With ophthalmic complications
0.000 0.152 0.848
E10.8 With unspecified complications
0.000 0.152 0.848
M06.3 Rheumatoid nodule
0.000 0.155 0.845
E14.6 With other specified complications
0.000 0.156 0.843
I10-I15 Hypertensive diseases
0.000 0.161 0.839
I12 Hypertensive renal disease
0.000 0.184 0.816
G35-G37 Demyelinating diseases of the central nervous system
0.812 0.188 0.000
E14.1 With ketoacidosis
0.000 0.196 0.804
E10.5 With peripheral circulatory complications
0.000 0.201 0.799
E14.8 With unspecified complications
0.000 0.203 0.796
I12.9 Hypertensive renal disease without renal failure
0.000 0.221 0.779
E13 Other specified diabetes mellitus
0.000 0.222 0.778
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.223 0.777
E14.2 Withrenal complications
0.000 0.226 0.774
E16.1 Other hypoglycaemia
0.000 0.228 0.772
L40.8 Other psoriasis
0.000 0.233 0.767
G37 Other demyelinating diseases of central nervous system
0.765 0.235 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.253 0.747
E14.4 With neurological complications
0.000 0.254 0.746
M06.34 Rheumatoid nodule (Hand)
0.000 0.255 0.745
L40.1 Generalised pustular psoriasis
0.000 0.258 0.742
E10.6 With other specified complications
0.000 0.270 0.730
E14.5 With peripheral circulatory complications
0.000 0.272 0.728
K90 Intestinal malabsorption
0.000 0.274 0.726
E20-E35 Disorders of other endocrine glands
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
I12.0 Hypertensive renal disease with renal failure
0.000 0.285 0.715
L40.4 Guttate psoriasis
0.000 0.297 0.703
L40.2 Acrodermatitis continua
0.000 0.297 0.703
G37.9 Demyelinating disease of central nervous system, unspecified
0.696 0.304 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.311 0.689
I11 Hypertensive heart disease
0.000 0.316 0.683
E28 Ovarian dysfunction
0.000 0.320 0.680
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.325 0.675
E50-E64 Other nutritional deficiencies
0.000 0.331 0.669
L40.3 Pustulosis palmaris et plantaris
0.000 0.331 0.668
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.343 0.657
E28.2 Polycystic ovarian syndrome
0.000 0.343 0.657
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.349 0.651
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.350 0.650
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.350 0.650
E16.4 Abnormal secretion of gastrin
0.000 0.350 0.650
E16.3 Increased secretion of glucagon
0.000 0.350 0.650
E15 Nondiabetic hypoglycaemic coma
0.000 0.350 0.650
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.648 0.352 0.000
I15 Secondary hypertension
0.000 0.359 0.641
E13.9 Without complications
0.000 0.361 0.639
E11.2 With renal complications
0.000 0.365 0.635
G36 Other acute disseminated demyelination
0.635 0.365 0.000
M06.2 Rheumatoid bursitis
0.000 0.370 0.630
M06.1 Adult-onset Still's disease
0.000 0.370 0.630
E22 Hyperfunction of pituitary gland
0.000 0.380 0.619
M06.8 Other specified rheumatoid arthritis
0.000 0.388 0.612
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.391 0.609
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.394 0.606
M06.38 Rheumatoid nodule (Other)
0.000 0.394 0.606
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.394 0.606
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.394 0.606
M06.33 Rheumatoid nodule (Forearm)
0.000 0.394 0.606
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.394 0.606
E55 Vitamin D deficiency
0.000 0.405 0.595
K90.9 Intestinal malabsorption, unspecified
0.000 0.409 0.591
K90.8 Other intestinal malabsorption
0.000 0.420 0.580
G37.8 Other specified demyelinating diseases of central nervous system
0.566 0.434 0.000
E40-E46 Malnutrition
0.000 0.438 0.562
I15.9 Seconday hypertension, unspecified
0.000 0.439 0.561
E13.8 With unspecified complications
0.000 0.442 0.558
E13.7 With multiple complications
0.000 0.442 0.558
E13.6 With other specified complications
0.000 0.442 0.558
E13.5 With peripheral circulatory complications
0.000 0.442 0.558
E13.4 With neurological complications
0.000 0.442 0.558
E13.2 With renal complications
0.000 0.442 0.558
E13.1 With ketoacidosis
0.000 0.442 0.558
E13.0 With coma
0.000 0.442 0.558
E11.8 With unspecified complications
0.000 0.443 0.557
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.446 0.554
M05-M14 Inflammatory polyarthropathies
0.000 0.447 0.553
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.448 0.552
G37.5 Concentric sclerosis [Balo]
0.548 0.452 0.000
G37.4 Subacute necrotising myelitis
0.548 0.452 0.000
G37.2 Central pontine myelinolysis
0.548 0.452 0.000
G37.1 Central demyelination of corpus callosum
0.548 0.452 0.000
G37.0 Diffuse sclerosis
0.548 0.452 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.458 0.542
E23 Hypofunction and other disorders of pituitary gland
0.000 0.459 0.541
E29 Testicular dysfunction
0.000 0.460 0.540
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.464 0.536
M05 Seropositive rheumatoid arthritis
0.000 0.467 0.533
E24 Cushing's syndrome
0.000 0.474 0.526
E13.3 With ophthalmic complications
0.000 0.474 0.526
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.475 0.525
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.476 0.524
E11.6 With other specified complications
0.000 0.476 0.523
K90.3 Pancreatic steatorrhoea
0.000 0.480 0.520
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.480 0.520
K90.1 Tropical sprue
0.000 0.480 0.520
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.485 0.515
E32 Diseases of thymus
0.000 0.485 0.515
E31 Polyglandular dysfunction
0.000 0.485 0.515
E30 Disorders of puberty, not elsewhere classified
0.000 0.485 0.515
E25 Adrenogenital disorders
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G36.0 Neuromyelitis optica [Devic]
0.508 0.492 0.000
E00-E07 Disorders of thyroid gland
0.000 0.492 0.508
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.501 0.499
I13 Hypertensive heart and renal disease
0.000 0.502 0.498
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.504 0.496
M07 Psoriatic and enteropathic arthropathies
0.000 0.506 0.494
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.506 0.494
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.506 0.494
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.506 0.494
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.506 0.494
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.506 0.494
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.506 0.494
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.506 0.494
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.506 0.494
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.508 0.492
E05.9 Thyrotoxicosis, unspecified
0.000 0.511 0.489
E28.9 Ovarian dysfunction, unspecified
0.000 0.512 0.488
E28.8 Other ovarian dysfunction
0.000 0.512 0.488
E28.1 Androgen excess
0.000 0.512 0.488
E28.0 Oestrogen excess
0.000 0.512 0.488
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.520 0.480
E63 Other nutritional deficiencies
0.000 0.520 0.480
E50 Vitamin A deficiency
0.000 0.520 0.480
E60 Dietary zinc deficiency
0.000 0.520 0.480
E59 Dietary selenium deficiency
0.000 0.520 0.480
E54 Ascorbic acid deficiency
0.000 0.520 0.480
E52 Niacin deficiency [pellagra]
0.000 0.520 0.480
E22.0 Acromegaly and pituitary gigantism
0.000 0.529 0.471
E70-E90 Metabolic disorders
0.000 0.530 0.470
E56 Other vitamin deficiencies
0.000 0.530 0.470
E58 Dietary calcium deficiency
0.000 0.531 0.469
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.531 0.469
E51 Thiamine deficiency
0.000 0.533 0.467
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.533 0.467
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.536 0.464
E28.3 Primary ovarian failure
0.000 0.539 0.461
M07.3 Other psoriatic arthropathies
0.000 0.540 0.460
I15.8 Other secondary hypertension
0.000 0.540 0.460
I15.2 Hypertension secondary to endocrine disorders
0.000 0.540 0.460
I15.0 Renovascular hypertension
0.000 0.542 0.458
E78.2 Mixed hyperlipidaemia
0.000 0.543 0.457
G36.9 Acute disseminated demyelination, unspecified
0.455 0.545 0.000
G36.8 Other specified acute disseminated demyelination
0.455 0.545 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.455 0.545 0.000
E20 Hypoparathyroidism
0.000 0.546 0.454
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.548 0.452
M06.18 Adult-onset Still's disease (Other)
0.000 0.548 0.452
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.548 0.452
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.548 0.452
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.548 0.452
M06.14 Adult-onset Still's disease (Hand)
0.000 0.548 0.452
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.548 0.452
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.548 0.452
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.548 0.452
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.548 0.452
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.548 0.452
M06.28 Rheumatoid bursitis (Other)
0.000 0.548 0.452
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.548 0.452
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.548 0.452
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.548 0.452
M06.24 Rheumatoid bursitis (Hand)
0.000 0.548 0.452
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.548 0.452
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.548 0.452
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.548 0.452
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.548 0.452
E23.7 Disorder of pituitary gland, unspecified
0.000 0.549 0.451
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.556 0.444
E22.8 Other hyperfunction of pituitary gland
0.000 0.556 0.444
E22.1 Hyperprolactinaemia
0.000 0.556 0.444
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.559 0.441
E61 Deficiency of other nutrient elements
0.000 0.559 0.441
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.561 0.439
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.561 0.439
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.561 0.439
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.561 0.439
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.561 0.439
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.561 0.439
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.561 0.439
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.561 0.439
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.561 0.439
E24.0 Pituitary-dependent Cushing's disease
0.000 0.564 0.436
E78.8 Other disorders of lipoprotein metabolism
0.000 0.572 0.428
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.572 0.428
E55.0 Rickets, active
0.000 0.573 0.427
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.579 0.421
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.580 0.420
E88 Other metabolic disorders
0.000 0.582 0.418
E24.2 Drug-induced Cushing's syndrome
0.000 0.585 0.414
E29.1 Testicular hypofunction
0.000 0.588 0.412
E23.2 Diabetes insipidus
0.000 0.592 0.408
E23.6 Other disorders of pituitary gland
0.000 0.592 0.408
M05.8 Other seropositive rheumatoid arthritis
0.000 0.597 0.403
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.597 0.403
E45 Retarded development following protein-energy malnutrition
0.000 0.597 0.403
E43 Unspecified severe protein-energy malnutrition
0.000 0.597 0.403
E42 Marasmic kwashiorkor
0.000 0.597 0.403
E41 Nutritional marasmus
0.000 0.597 0.403
E40 Kwashiorkor
0.000 0.597 0.403
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.604 0.396
M08 Juvenile arthritis
0.000 0.604 0.396
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.604 0.396
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.607 0.392
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.611 0.389
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.612 0.388
E23.1 Drug-induced hypopituitarism
0.000 0.612 0.388
E29.9 Testicular dysfunction, unspecified
0.000 0.612 0.387
E29.8 Other testicular dysfunction
0.000 0.612 0.387
E29.0 Testicular hyperfunction
0.000 0.612 0.387
M12 Other specific arthropathies
0.000 0.613 0.387
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.618 0.382
M05.1 Rheumatoid lung disease
0.000 0.618 0.382
M05.0 Felty's syndrome
0.000 0.618 0.382
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.618 0.382
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.622 0.377
E24.3 Ectopic ACTH syndrome
0.000 0.622 0.377
E24.1 Nelson's syndrome
0.000 0.622 0.377
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.624 0.376
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.624 0.376
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.624 0.376
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.624 0.376
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.624 0.376
E25.9 Adrenogenital disorder, unspecified
0.000 0.630 0.369
E25.8 Other adrenogenital disorders
0.000 0.630 0.369
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.630 0.369
E30.9 Disorder of puberty, unspecified
0.000 0.630 0.369
E30.8 Other disorders of puberty
0.000 0.630 0.369
E30.1 Precocious puberty
0.000 0.630 0.369
E30.0 Delayed puberty
0.000 0.630 0.369
E31.9 Polyglandular dysfunction, unspecified
0.000 0.630 0.369
E31.8 Other polyglandular dysfunction
0.000 0.630 0.369
E31.1 Polyglandular hyperfunction
0.000 0.630 0.369
E31.0 Autoimmune polyglandular failure
0.000 0.630 0.369
E32.9 Disease of thymus, unspecified
0.000 0.630 0.369
E32.8 Other diseases of thymus
0.000 0.630 0.369
E32.1 Abscess of thymus
0.000 0.630 0.369
E32.0 Persistent hyperplasia of thymus
0.000 0.630 0.369
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.630 0.369
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.630 0.369
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.630 0.369
M11 Other crystal arthropathies
0.000 0.632 0.368
E26 Hyperaldosteronism
0.000 0.634 0.366
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.635 0.364
E00 Congenital iodine-deficiency syndrome
0.000 0.635 0.364
E53 Deficiency of other B group vitamins
0.000 0.640 0.360
E34 Other endocrine disorders
0.000 0.641 0.359
E74 Other disorders of carbohydrate metabolism
0.000 0.641 0.359
E05.5 Thyroid crisis or storm
0.000 0.642 0.358
E05.4 Thyrotoxicosis factitia
0.000 0.642 0.358
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.642 0.358
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.642 0.358
E78.1 Pure hyperglyceridaemia
0.000 0.642 0.358
E79 Disorders of purine and pyrimidine metabolism
0.000 0.643 0.357
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.643 0.357
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.643 0.357
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.643 0.357
M07.5 Arthropathy in ulcerative colitis
0.000 0.645 0.354
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.645 0.354
M07.2 Psoriatic spondylitis
0.000 0.645 0.354
M07.1 Arthritis mutilans
0.000 0.645 0.354
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.645 0.354
E78.6 Lipoprotein deficiency
0.000 0.647 0.353
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.648 0.352
E27 Other disorders of adrenal gland
0.000 0.651 0.349
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.654 0.346
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.655 0.345
E50.9 Vitamin A deficiency, unspecified
0.000 0.656 0.344
E50.8 Other manifestations of vitamin A deficiency
0.000 0.656 0.344
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.656 0.344
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.656 0.344
E50.5 Vitamin A deficiency with night blindness
0.000 0.656 0.344
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.656 0.344
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.656 0.344
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.656 0.344
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.656 0.344
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.656 0.344
E63.9 Nutritional deficiency, unspecified
0.000 0.656 0.344
E63.8 Other specified nutritional deficiencies
0.000 0.656 0.344
E63.1 Imbalance of constituents of food intake
0.000 0.656 0.344
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.656 0.344
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.656 0.344
E64.8 Sequelae of other nutritional deficiencies
0.000 0.656 0.344
E64.3 Sequelae of rickets
0.000 0.656 0.344
E64.2 Sequelae of vitamin C deficiency
0.000 0.656 0.344
E64.1 Sequelae of vitamin A deficiency
0.000 0.656 0.344
E64.0 Sequelae of protein-energy malnutrition
0.000 0.656 0.344
E24.8 Other Cushing's syndrome
0.000 0.658 0.342
E21.3 Hyperparathyroidism, unspecified
0.000 0.661 0.339
E77 Disorders of glycoprotein metabolism
0.000 0.663 0.337
E76 Disorders of glycosaminoglycan metabolism
0.000 0.663 0.337
E72 Other disorders of amino-acid metabolism
0.000 0.663 0.337
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.663 0.337
E70 Disorders of aromatic amino-acid metabolism
0.000 0.663 0.337
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.663 0.337
E56.9 Vitamin deficiency, unspecified
0.000 0.663 0.337
E56.8 Deficiency of other vitamins
0.000 0.663 0.337
E56.0 Deficiency of vitamin E
0.000 0.663 0.337
M14 Arthropathies in other diseases classified elsewhere
0.000 0.663 0.337
E51.9 Thiamine deficiency, unspecified
0.000 0.665 0.335
E51.8 Other manifestations of thiamine deficiency
0.000 0.665 0.335
E51.1 Beriberi
0.000 0.665 0.335
L40-L45 Papulosquamous disorders
0.000 0.665 0.335
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.666 0.334
M07.38 Other psoriatic arthropathies (Other)
0.000 0.670 0.330
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.670 0.330
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.670 0.330
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.670 0.330
E56.1 Deficiency of vitamin K
0.000 0.672 0.327
E78.4 Other hyperlipidaemia
0.000 0.673 0.327
E20.8 Other hypoparathyroidism
0.000 0.674 0.325
E20.1 Pseudohypoparathyroidism
0.000 0.674 0.325
E20.0 Idiopathic hypoparathyroidism
0.000 0.674 0.325
E88.8 Other specified metabolic disorders
0.000 0.677 0.323
E51.2 Wernicke's encephalopathy
0.000 0.677 0.322
I15.1 Hypertension secondary to other renal disorders
0.000 0.677 0.322
M07.6 Other enteropathic arthropathies
0.000 0.678 0.322
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.680 0.320
E05.8 Other thyrotoxicosis
0.000 0.681 0.319
E84 Cystic fibrosis
0.000 0.681 0.319
E78.0 Pure hypercholesterolaemia
0.000 0.681 0.319
E21.4 Other specified disorders of parathyroid gland
0.000 0.684 0.316
E21.2 Other hyperparathyroidism
0.000 0.684 0.316
E61.9 Deficiency of nutrient element, unspecified
0.000 0.684 0.316
E61.8 Deficiency of other specified nutrient elements
0.000 0.684 0.316
E61.7 Deficiency of multiple nutrient elements
0.000 0.684 0.316
E61.6 Vanadium deficiency
0.000 0.684 0.316
E61.5 Molybdenum deficiency
0.000 0.684 0.316
E61.4 Chromium deficiency
0.000 0.684 0.316
E61.3 Manganese deficiency
0.000 0.684 0.316
E61.0 Copper deficiency
0.000 0.684 0.316
E78.3 Hyperchylomicronaemia
0.000 0.685 0.315
E88.9 Metabolic disorder, unspecified
0.000 0.686 0.314
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.686 0.314
E46 Unspecified protein-energy malnutrition
0.000 0.687 0.313
E78.5 Hyperlipidaemia, unspecified
0.000 0.688 0.312
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.690 0.310
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.693 0.307
E61.2 Magnesium deficiency
0.000 0.693 0.307
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.699 0.301
E73 Lactose intolerance
0.000 0.701 0.299
E03 Other hypothyroidism
0.000 0.702 0.298
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.706 0.294
E27.9 Disorder of adrenal gland, unspecified
0.000 0.708 0.292
E88.2 Lipomatosis, not elsewhere classified
0.000 0.710 0.290
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.711 0.289
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.711 0.289
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.711 0.289
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.711 0.289
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.711 0.289
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.711 0.289
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.711 0.289
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.711 0.289
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.711 0.289
E44.1 Mild protein-energy malnutrition
0.000 0.711 0.289
E44.0 Moderate protein-energy malnutrition
0.000 0.711 0.289
E61.1 Iron deficiency
0.000 0.712 0.288
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.001 0.712 0.288
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.713 0.287
M08.9 Juvenile arthritis, unspecified
0.000 0.716 0.284
M08.8 Other juvenile arthritis
0.000 0.716 0.284
M08.4 Pauciarticular juvenile arthritis
0.000 0.716 0.284
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.716 0.284
M08.2 Juvenile arthritis with systemic onset
0.000 0.716 0.284
M08.1 Juvenile ankylosing spondylitis
0.000 0.716 0.284
M08.0 Juvenile rheumatoid arthritis
0.000 0.716 0.284
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.716 0.284
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.716 0.284
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.716 0.284
M09.0 Juvenile arthritis in psoriasis
0.000 0.716 0.284
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.717 0.283
M12.2 Villonodular synovitis (pigmented)
0.000 0.717 0.283
E24.9 Cushing's syndrome, unspecified
0.000 0.717 0.283
M10 Gout
0.000 0.722 0.278
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.723 0.277
M12.5 Traumatic arthropathy
0.000 0.723 0.277
M12.4 Intermittent hydrarthrosis
0.000 0.723 0.277
M12.1 Kaschin-Beck disease
0.000 0.723 0.277
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.723 0.277
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.723 0.277
M05.2 Rheumatoid vasculitis
0.001 0.723 0.277
E88.3 Tumour lysis syndrome
0.000 0.723 0.277
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.723 0.276
M05.09 Felty's syndrome (Site unspecified)
0.000 0.726 0.274
M05.08 Felty's syndrome (Other)
0.000 0.726 0.274
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.726 0.274
M05.06 Felty's syndrome (Lower leg)
0.000 0.726 0.274
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.726 0.274
M05.04 Felty's syndrome (Hand)
0.000 0.726 0.274
M05.03 Felty's syndrome (Forearm)
0.000 0.726 0.274
M05.02 Felty's syndrome (Upper arm)
0.000 0.726 0.274
M05.01 Felty's syndrome (Shoulder region)
0.000 0.726 0.274
M05.00 Felty's syndrome (Multiple sites)
0.000 0.726 0.274
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.726 0.274
M05.18 Rheumatoid lung disease (Other)
0.000 0.726 0.274
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.726 0.274
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.726 0.274
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.726 0.274
M05.14 Rheumatoid lung disease (Hand)
0.000 0.726 0.274
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.726 0.274
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.726 0.274
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.726 0.274
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.726 0.274
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.726 0.274
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.726 0.274
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.726 0.274
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.726 0.274
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.726 0.274
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.726 0.274
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.726 0.274
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.726 0.274
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.726 0.274
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.726 0.274
E65-E68 Obesity and other hyperalimentation
0.000 0.726 0.274
E07 Other disorders of thyroid
0.000 0.727 0.273
E85 Amyloidosis
0.000 0.728 0.272
M11.2 Other chondrocalcinosis
0.000 0.729 0.271
M06.0 Seronegative rheumatoid arthritis
0.000 0.729 0.270
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.731 0.269
M11.1 Familial chondrocalcinosis
0.000 0.736 0.264
M11.0 Hydroxyapatite deposition disease
0.000 0.736 0.264
E20.9 Hypoparathyroidism, unspecified
0.000 0.736 0.264
E26.8 Other hyperaldosteronism
0.000 0.737 0.262
E26.1 Secondary hyperaldosteronism
0.000 0.737 0.262
J45 Asthma
0.000 0.738 0.262
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.738 0.261
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.738 0.261
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.738 0.261
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.738 0.261
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.738 0.261
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.738 0.261
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.738 0.261
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.738 0.261
M12.3 Palindromic rheumatism
0.000 0.739 0.261
E53.1 Pyridoxine deficiency
0.000 0.741 0.258
E53.0 Riboflavin deficiency
0.000 0.741 0.258
M11.9 Crystal arthropathy, unspecified
0.000 0.742 0.257
E34.5 Androgen resistance syndrome
0.000 0.742 0.257
E34.4 Constitutional tall stature
0.000 0.742 0.257
E34.3 Short stature, not elsewhere classified
0.000 0.742 0.257
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.742 0.257
E34.1 Other hypersecretion of intestinal hormones
0.000 0.742 0.257
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.743 0.257
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.743 0.257
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.743 0.257
E74.2 Disorders of galactose metabolism
0.000 0.743 0.257
E74.1 Disorders of fructose metabolism
0.000 0.743 0.257
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.744 0.256

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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