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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3095307
log Bayes Factor = 78.2795
Chromosome 6   position 31,092,049  (GRCh37) Explore rs3095307 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
G35 Multiple sclerosis
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
K51 Ulcerative colitis
0.000 0.005 0.995
K51.9 Ulcerative colitis, unspecified
0.000 0.007 0.993
E03 Other hypothyroidism
0.000 0.007 0.993
E03.9 Hypothyroidism, unspecified
0.000 0.009 0.991
L40 Psoriasis
0.986 0.014 0.000
K51.4 Pseudopolyposis of colon
0.000 0.014 0.986
L40.5 Arthropathic psoriasis
0.957 0.043 0.000
E06 Thyroiditis
0.000 0.054 0.946
K51.2 Ulcerative (chronic) proctitis
0.000 0.058 0.942
E06.3 Autoimmune thyroiditis
0.000 0.088 0.912
L40.0 Psoriasis vulgaris
0.906 0.094 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.106 0.894
K50-K52 Noninfective enteritis and colitis
0.000 0.106 0.894
K52 Other non-infective gastro-enteritis and colitis
0.000 0.112 0.888
J47 Bronchiectasis
0.000 0.166 0.834
K51.5 Mucosal proctocolitis
0.000 0.169 0.831
K51.8 Other ulcerative colitis
0.000 0.174 0.826
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.183 0.817
L40.8 Other psoriasis
0.816 0.184 0.000
L40.4 Guttate psoriasis
0.813 0.187 0.000
E05.8 Other thyrotoxicosis
0.000 0.211 0.789
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.236 0.764
K52.3 Indeterminate colitis
0.000 0.242 0.758
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.249 0.751
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.266 0.734
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.272 0.728
E06.9 Thyroiditis, unspecified
0.000 0.273 0.727
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.274 0.726
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.276 0.724
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E03.5 Myxoedema coma
0.000 0.288 0.712
E03.4 Atrophy of thyroid (acquired)
0.000 0.288 0.712
E03.3 Postinfectious hypothyroidism
0.000 0.288 0.712
L40.1 Generalised pustular psoriasis
0.711 0.289 0.000
L40.2 Acrodermatitis continua
0.707 0.293 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.297 0.703
E50-E64 Other nutritional deficiencies
0.000 0.301 0.699
E03.8 Other specified hypothyroidism
0.000 0.308 0.691
E53 Deficiency of other B group vitamins
0.000 0.319 0.681
K90 Intestinal malabsorption
0.002 0.320 0.678
E06.4 Drug-induced thyroiditis
0.000 0.322 0.678
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.322 0.678
E06.0 Acute thyroiditis
0.000 0.322 0.678
E53.8 Deficiency of other specified B group vitamins
0.000 0.345 0.655
E06.5 Other chronic thyroiditis
0.000 0.354 0.646
E10-E14 Diabetes mellitus
0.000 0.356 0.644
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.372 0.628
E10 Insulin-dependent diabetes mellitus
0.000 0.374 0.626
E06.1 Subacute thyroiditis
0.000 0.374 0.626
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.376 0.624
E03.1 Congenital hypothyroidism without goitre
0.000 0.379 0.621
L40.3 Pustulosis palmaris et plantaris
0.620 0.379 0.000
E10.3 With ophthalmic complications
0.000 0.392 0.608
E10.2 With renal complications
0.000 0.396 0.604
E65-E68 Obesity and other hyperalimentation
0.000 0.396 0.604
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.399 0.601
E07 Other disorders of thyroid
0.000 0.407 0.593
K90.8 Other intestinal malabsorption
0.001 0.418 0.581
E53.9 Vitamin B deficiency, unspecified
0.000 0.419 0.581
E40-E46 Malnutrition
0.000 0.438 0.562
E10.4 With neurological complications
0.000 0.447 0.553
E51 Thiamine deficiency
0.000 0.460 0.540
K90.9 Intestinal malabsorption, unspecified
0.000 0.466 0.533
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.475 0.525
E55 Vitamin D deficiency
0.000 0.480 0.520
G37 Other demyelinating diseases of central nervous system
0.000 0.481 0.519
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.512
E66 Obesity
0.000 0.494 0.506
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.498 0.501
E63 Other nutritional deficiencies
0.000 0.498 0.501
E50 Vitamin A deficiency
0.000 0.498 0.501
E60 Dietary zinc deficiency
0.000 0.498 0.501
E59 Dietary selenium deficiency
0.000 0.498 0.501
E52 Niacin deficiency [pellagra]
0.000 0.498 0.501
E56 Other vitamin deficiencies
0.000 0.501 0.499
E66.8 Other obesity
0.000 0.504 0.496
E61 Deficiency of other nutrient elements
0.000 0.504 0.496
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.511 0.489
E53.1 Pyridoxine deficiency
0.000 0.512 0.488
E53.0 Riboflavin deficiency
0.000 0.512 0.488
K90.3 Pancreatic steatorrhoea
0.001 0.513 0.486
K90.2 Blind loop syndrome, not elsewhere classified
0.001 0.513 0.486
K90.1 Tropical sprue
0.001 0.513 0.486
E54 Ascorbic acid deficiency
0.000 0.515 0.485
E10.7 With multiple complications
0.000 0.517 0.483
E58 Dietary calcium deficiency
0.000 0.524 0.476
E14 Unspecified diabetes mellitus
0.000 0.528 0.472
E12 Malnutrition-related diabetes mellitus
0.000 0.538 0.461
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.001 0.542 0.457
M35.0 Sicca syndrome [Sjogren]
0.000 0.543 0.457
E65 Localised adiposity
0.000 0.547 0.453
E07.8 Other specified disorders of thyroid
0.000 0.549 0.451
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.553 0.447
E46 Unspecified protein-energy malnutrition
0.000 0.553 0.447
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.567 0.433
E67 Other hyperalimentation
0.000 0.567 0.433
E68 Sequelae of hyperalimentation
0.000 0.567 0.433
G36 Other acute disseminated demyelination
0.000 0.570 0.430
E61.2 Magnesium deficiency
0.000 0.573 0.427
E10.0 With coma
0.000 0.574 0.426
E51.2 Wernicke's encephalopathy
0.000 0.574 0.426
E13 Other specified diabetes mellitus
0.000 0.574 0.426
E07.1 Dyshormogenetic goitre
0.000 0.575 0.425
E07.0 Hypersecretion of calcitonin
0.000 0.575 0.425
E10.1 With ketoacidosis
0.000 0.575 0.424
E10.8 With unspecified complications
0.000 0.596 0.404
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.597 0.403
E45 Retarded development following protein-energy malnutrition
0.000 0.597 0.403
E43 Unspecified severe protein-energy malnutrition
0.000 0.597 0.403
E42 Marasmic kwashiorkor
0.000 0.597 0.403
E41 Nutritional marasmus
0.000 0.597 0.403
E40 Kwashiorkor
0.000 0.597 0.403
E14.8 With unspecified complications
0.000 0.599 0.401
E14.3 With ophthalmic complications
0.000 0.607 0.393
N20.0 Calculus of kidney
0.393 0.607 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.609 0.391
E51.9 Thiamine deficiency, unspecified
0.000 0.613 0.387
E51.8 Other manifestations of thiamine deficiency
0.000 0.613 0.387
E51.1 Beriberi
0.000 0.613 0.387
E14.2 Withrenal complications
0.000 0.617 0.383
K52.1 Toxic gastro-enteritis and colitis
0.000 0.623 0.376
E66.0 Obesity due to excess calories
0.000 0.625 0.375
E55.0 Rickets, active
0.000 0.627 0.373
G37.5 Concentric sclerosis [Balo]
0.000 0.628 0.372
G37.4 Subacute necrotising myelitis
0.000 0.628 0.372
G37.2 Central pontine myelinolysis
0.000 0.628 0.372
G37.1 Central demyelination of corpus callosum
0.000 0.628 0.372
G37.0 Diffuse sclerosis
0.000 0.628 0.372
E14.5 With peripheral circulatory complications
0.000 0.629 0.371
E66.1 Drug-induced obesity
0.000 0.637 0.363
E50.9 Vitamin A deficiency, unspecified
0.000 0.640 0.360
E50.8 Other manifestations of vitamin A deficiency
0.000 0.640 0.360
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.640 0.360
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.640 0.360
E50.5 Vitamin A deficiency with night blindness
0.000 0.640 0.360
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.640 0.360
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.640 0.360
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.640 0.360
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.640 0.360
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.640 0.360
E63.9 Nutritional deficiency, unspecified
0.000 0.640 0.360
E63.8 Other specified nutritional deficiencies
0.000 0.640 0.360
E63.1 Imbalance of constituents of food intake
0.000 0.640 0.360
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.640 0.360
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.640 0.360
E64.8 Sequelae of other nutritional deficiencies
0.000 0.640 0.360
E64.3 Sequelae of rickets
0.000 0.640 0.360
E64.2 Sequelae of vitamin C deficiency
0.000 0.640 0.360
E64.1 Sequelae of vitamin A deficiency
0.000 0.640 0.360
E64.0 Sequelae of protein-energy malnutrition
0.000 0.640 0.360
E10.6 With other specified complications
0.000 0.641 0.359
E56.9 Vitamin deficiency, unspecified
0.000 0.642 0.358
E56.8 Deficiency of other vitamins
0.000 0.642 0.358
E56.0 Deficiency of vitamin E
0.000 0.642 0.358
E56.1 Deficiency of vitamin K
0.000 0.644 0.355
E61.9 Deficiency of nutrient element, unspecified
0.000 0.644 0.355
E61.8 Deficiency of other specified nutrient elements
0.000 0.644 0.355
E61.7 Deficiency of multiple nutrient elements
0.000 0.644 0.355
E61.6 Vanadium deficiency
0.000 0.644 0.355
E61.5 Molybdenum deficiency
0.000 0.644 0.355
E61.4 Chromium deficiency
0.000 0.644 0.355
E61.3 Manganese deficiency
0.000 0.644 0.355
E61.0 Copper deficiency
0.000 0.644 0.355
E15 Nondiabetic hypoglycaemic coma
0.000 0.649 0.351
E13.3 With ophthalmic complications
0.000 0.650 0.350
E14.6 With other specified complications
0.000 0.658 0.342
E14.7 With multiple complications
0.000 0.662 0.338
E14.0 With coma
0.000 0.662 0.338
E04 Other non-toxic goitre
0.000 0.663 0.337
N20 Calculus of kidney and ureter
0.333 0.667 0.000
E12.9 Without complications
0.000 0.669 0.331
E12.8 With unspecified complications
0.000 0.669 0.331
E12.7 With multiple complications
0.000 0.669 0.331
E12.6 With other specified complications
0.000 0.669 0.331
E12.5 With peripheral circulatory complications
0.000 0.669 0.331
E12.4 With neurological complications
0.000 0.669 0.331
E12.3 With ophthalmic complications
0.000 0.669 0.331
E12.2 With renal complications
0.000 0.669 0.331
E12.1 With ketoacidosis
0.000 0.669 0.331
E12.0 With coma
0.000 0.669 0.331
L40-L45 Papulosquamous disorders
0.327 0.670 0.003
N20.1 Calculus of ureter
0.329 0.671 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.679 0.321
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.684 0.316
E14.1 With ketoacidosis
0.000 0.687 0.313
E67.8 Other specified hyperalimentation
0.000 0.689 0.310
E67.3 Hypervitaminosis D
0.000 0.689 0.310
E67.2 Megavitamin-B6 syndrome
0.000 0.689 0.310
E67.1 Hypercarotenaemia
0.000 0.689 0.310
E67.0 Hypervitaminosis A
0.000 0.689 0.310
G36.9 Acute disseminated demyelination, unspecified
0.000 0.692 0.308
G36.8 Other specified acute disseminated demyelination
0.000 0.692 0.308
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.692 0.308
E04.0 Non-toxic diffuse goitre
0.000 0.692 0.308
G36.0 Neuromyelitis optica [Devic]
0.000 0.693 0.307
E13.8 With unspecified complications
0.000 0.694 0.305
E13.7 With multiple complications
0.000 0.694 0.305
E13.6 With other specified complications
0.000 0.694 0.305
E13.5 With peripheral circulatory complications
0.000 0.694 0.305
E13.4 With neurological complications
0.000 0.694 0.305
E13.2 With renal complications
0.000 0.694 0.305
E13.1 With ketoacidosis
0.000 0.694 0.305
E13.0 With coma
0.000 0.694 0.305
E44.1 Mild protein-energy malnutrition
0.000 0.711 0.289
E44.0 Moderate protein-energy malnutrition
0.000 0.711 0.289
E10.5 With peripheral circulatory complications
0.000 0.713 0.287
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.713 0.287
E14.4 With neurological complications
0.000 0.724 0.276
Z93.2 Ileostomy status
0.000 0.735 0.265
L41 Parapsoriasis
0.262 0.736 0.002
K92.1 Melaena
0.262 0.738 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.748 0.252
K92 Other diseases of digestive system
0.243 0.753 0.004
L42 Pityriasis rosea
0.243 0.755 0.002
L44 Other papulosquamous disorders
0.242 0.756 0.002
E04.8 Other specified non-toxic goitre
0.000 0.758 0.242
L45 Papulosquamous disorders in diseases classified elsewhere
0.235 0.763 0.002
K92.2 Gastro-intestinal haemorrhage, unspecified
0.237 0.763 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.765 0.235
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.770 0.230
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.770 0.230
E16.4 Abnormal secretion of gastrin
0.000 0.770 0.230
E16.3 Increased secretion of glucagon
0.000 0.770 0.230
N20-N23 Urolithiasis
0.223 0.777 0.000
K92.0 Haematemesis
0.220 0.780 0.000
L41.1 Pityriasis lichenoides chronica
0.215 0.783 0.001
N21 Calculus of lower urinary tract
0.205 0.795 0.000
E61.1 Iron deficiency
0.000 0.801 0.199
N21.0 Calculus in bladder
0.192 0.808 0.000
L41.9 Parapsoriasis, unspecified
0.188 0.811 0.002
L41.8 Other parapsoriasis
0.188 0.811 0.002
L41.5 Retiform parapsoriasis
0.188 0.811 0.002
L41.4 Large plaque parapsoriasis
0.188 0.811 0.002
L41.3 Small plaque parapsoriasis
0.188 0.811 0.002
L41.2 Lymphomatoid papulosis
0.188 0.811 0.002
L41.0 Pityriasis lichenoides et varioliformis acuta
0.188 0.811 0.002
L44.0 Pityriasis rubra pilaris
0.181 0.818 0.002
F41.2 Mixed anxiety and depressive disorder
0.181 0.819 0.000
E13.9 Without complications
0.000 0.822 0.178
K92.9 Disease of digestive system, unspecified
0.174 0.824 0.001
L44.9 Papulosquamous disorder, unspecified
0.173 0.825 0.002
L44.8 Other specified papulosquamous disorders
0.173 0.825 0.002
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.173 0.825 0.002
L44.3 Lichen ruber moniliformis
0.173 0.825 0.002
L44.2 Lichen striatus
0.173 0.825 0.002
L44.1 Lichen nitidus
0.173 0.825 0.002
N21.1 Calculus in urethra
0.169 0.831 0.000
K90-K93 Other diseases of the digestive system
0.031 0.835 0.134
E16.1 Other hypoglycaemia
0.000 0.835 0.164
N22 Calculus of urinary tract in diseases classified elsewhere
0.160 0.840 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.158 0.842 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.850 0.150
J40-J47 Chronic lower respiratory diseases
0.000 0.852 0.148
N23 Unspecified renal colic
0.146 0.854 0.000
R31 Unspecified haematuria
0.139 0.861 0.000
J40 Bronchitis, not specified as acute or chronic
0.000 0.863 0.137
E16.2 Hypoglycaemia, unspecified
0.000 0.864 0.136
E11 Non-insulin-dependent diabetes mellitus
0.000 0.877 0.123
K93 Disorders of other digestive organs in diseases classified elsewhere
0.023 0.881 0.096
J44 Other chronic obstructive pulmonary disease
0.000 0.883 0.117
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.884 0.116
N22.8 Calculus of urinary tract in other diseases classified elsewhere
0.115 0.885 0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]
0.115 0.885 0.000
N20.9 Urinary calculus, unspecified
0.111 0.889 0.000
E11.8 With unspecified complications
0.000 0.891 0.109
J41 Simple and mucopurulent chronic bronchitis
0.000 0.895 0.105
L43 Lichen planus
0.100 0.898 0.003
N21.8 Other lower urinary tract calculus
0.096 0.903 0.000
E11.3 With ophthalmic complications
0.000 0.904 0.096
J42 Unspecified chronic bronchitis
0.000 0.905 0.095
K92.8 Other specified diseases of digestive system
0.090 0.905 0.004
M35 Other systemic involvement of connective tissue
0.000 0.906 0.094
E11.6 With other specified complications
0.000 0.909 0.091
E11.0 With coma
0.000 0.911 0.089
N20.2 Calculus of kidney with calculus of ureter
0.087 0.913 0.000
E11.7 With multiple complications
0.000 0.914 0.086
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.016 0.915 0.069
K93.1 Megacolon in Chagas' disease
0.016 0.915 0.069
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.016 0.915 0.069
F41 Other anxiety disorders
0.082 0.918 0.000
J43 Emphysema
0.000 0.919 0.081
M35.7 Hypermobility syndrome
0.000 0.920 0.080
E11.2 With renal complications
0.000 0.922 0.078
F41.9 Anxiety disorder, unspecified
0.076 0.924 0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.924 0.075
J41.1 Mucopurulent chronic bronchitis
0.000 0.924 0.075
J41.0 Simple chronic bronchitis
0.000 0.926 0.074
L43.3 Subacute (active) lichen planus
0.072 0.926 0.002
L43.2 Lichenoid drug reaction
0.072 0.926 0.002
L43.1 Bullous lichen planus
0.072 0.926 0.002
L43.0 Hypertrophic lichen planus
0.072 0.926 0.002
E11.1 With ketoacidosis
0.000 0.929 0.071
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.929 0.071
R63.8 Other symptoms and signs concerning food and fluid intake
0.000 0.930 0.070
R63.4 Abnormal weight loss
0.000 0.932 0.068
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.932 0.068
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.932 0.068
M35.5 Multifocal fibrosclerosis
0.000 0.932 0.068
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.932 0.068
E04.9 Non-toxic goitre, unspecified
0.000 0.934 0.066
R63 Symptoms and signs concerning food and fluid intake
0.000 0.934 0.066
E04.1 Non-toxic single thyroid nodule
0.000 0.934 0.066
M35.2 Behcet's disease
0.000 0.935 0.064
E11.5 With peripheral circulatory complications
0.000 0.936 0.064
M35.8 Other specified systemic involvement of connective tissue
0.000 0.937 0.063
J43.8 Other emphysema
0.000 0.937 0.063
J43.2 Centrilobular emphysema
0.000 0.938 0.062
Chapter XI Diseases of the digestive system
0.000 0.938 0.062
J43.1 Panlobular emphysema
0.000 0.942 0.058
J43.0 MacLeod's syndrome
0.000 0.942 0.058
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.058 0.942 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.008 0.943 0.050
R63.0 Anorexia
0.000 0.943 0.057
R30.0 Dysuria
0.056 0.944 0.000
E83.1 Disorders of iron metabolism
0.000 0.945 0.055
E89.0 Postprocedural hypothyroidism
0.000 0.946 0.054
R63.5 Abnormal weight gain
0.000 0.946 0.053
E70-E90 Metabolic disorders
0.000 0.947 0.053
E83 Disorders of mineral metabolism
0.000 0.947 0.053
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.948 0.052
F41.8 Other specified anxiety disorders
0.052 0.948 0.000
M35.1 Other overlap syndromes
0.000 0.948 0.051
R30 Pain associated with micturition
0.051 0.949 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.000 0.950 0.050
F41.3 Other mixed anxiety disorders
0.049 0.951 0.000
K91.4 Colostomy and enterostomy malfunction
0.000 0.951 0.049
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.951 0.049
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.952 0.048
L43.8 Other lichen planus
0.045 0.952 0.003
R63.2 Polyphagia
0.000 0.952 0.047
R30-R39 Symptoms and signs involving the urinary system
0.047 0.953 0.000
R63.3 Feeding difficulties and mismanagement
0.000 0.954 0.046
E83.3 Disorders of phosphorus metabolism
0.000 0.956 0.044
E10.9 Without complications
0.000 0.957 0.043
F41.1 Generalised anxiety disorder
0.043 0.957 0.000
K50 Crohn's disease [regional enteritis]
0.000 0.958 0.042
R34 Anuria and oliguria
0.042 0.958 0.000
R30.1 Vesical tenesmus
0.041 0.959 0.000
E73 Lactose intolerance
0.000 0.960 0.040
K91.2 Postsurgical malabsorption, not elsewhere classified
0.005 0.960 0.035
E84 Cystic fibrosis
0.000 0.960 0.040
E77 Disorders of glycoprotein metabolism
0.000 0.961 0.038
E76 Disorders of glycosaminoglycan metabolism
0.000 0.961 0.038
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.961 0.038
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.961 0.038
E83.8 Other disorders of mineral metabolism
0.000 0.962 0.038
E83.2 Disorders of zinc metabolism
0.000 0.962 0.038
E83.0 Disorders of copper metabolism
0.000 0.962 0.038
E83.4 Disorders of magnesium metabolism
0.000 0.962 0.038
K70.9 Alcoholic liver disease, unspecified
0.000 0.962 0.038
D80-D89 Certain disorders involving the immune mechanism
0.000 0.963 0.037
E70 Disorders of aromatic amino-acid metabolism
0.000 0.963 0.037
K91.9 Postprocedural disorder of digestive system, unspecified
0.006 0.964 0.030
E89.4 Postprocedural ovarian failure
0.000 0.964 0.036
D84 Other immunodeficiencies
0.000 0.965 0.035
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.965 0.035
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.965 0.035
K91.0 Vomiting following gastro-intestinal surgery
0.005 0.966 0.029
D86 Sarcoidosis
0.000 0.966 0.034
E20-E35 Disorders of other endocrine glands
0.000 0.966 0.034
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.966 0.034
E79 Disorders of purine and pyrimidine metabolism
0.000 0.966 0.034
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.966 0.034
D80 Immunodeficiency with predominantly antibody defects
0.000 0.966 0.034
D84.9 Immunodeficiency, unspecified
0.000 0.967 0.033
D86.9 Sarcoidosis, unspecified
0.000 0.967 0.033
K91.5 Postcholecystectomy syndrome
0.006 0.967 0.027
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.967 0.033
E72 Other disorders of amino-acid metabolism
0.000 0.967 0.032
K70 Alcoholic liver disease
0.000 0.968 0.032
E84.9 Cystic fibrosis, unspecified
0.000 0.968 0.032
E89.5 Postprocedural testicular hypofunction
0.000 0.969 0.031
E74 Other disorders of carbohydrate metabolism
0.000 0.969 0.031
D83 Common variable immunodeficiency
0.000 0.969 0.031
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.969 0.031
K70-K77 Diseases of liver
0.000 0.969 0.031
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.969 0.031
E73.9 Lactose intolerance, unspecified
0.000 0.969 0.031
K91.1 Postgastric surgery syndromes
0.007 0.969 0.024
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.970 0.030
M35.3 Polymyalgia rheumatica
0.000 0.970 0.030
E89.1 Postprocedural hypoinsulinaemia
0.000 0.971 0.029
R39 Other symptoms and signs involving the urinary system
0.029 0.971 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.971 0.029
E73.8 Other lactose intolerance
0.000 0.971 0.029
E73.1 Secondary lactase deficiency
0.000 0.971 0.029
E73.0 Congenital lactase deficiency
0.000 0.971 0.029
E84.8 Cystic fibrosis with other manifestations
0.000 0.971 0.029
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.971 0.029
D84.8 Other specified immunodeficiencies
0.000 0.971 0.029
R30.9 Painful micturition, unspecified
0.028 0.971 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.972 0.028
J46 Status asthmaticus
0.000 0.972 0.028
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.972 0.028
E71.3 Disorders of fatty-acid metabolism
0.000 0.972 0.028
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.972 0.028
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.972 0.028
E71.0 Maple-syrup-urine disease
0.000 0.972 0.028
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.972 0.028
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.972 0.028
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.972 0.028
E76.2 Other mucopolysaccharidoses
0.000 0.972 0.028
E76.1 Mucopolysaccharidosis, type II
0.000 0.972 0.028
E76.0 Mucopolysaccharidosis, type I
0.000 0.972 0.028
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.972 0.028
E77.8 Other disorders of glycoprotein metabolism
0.000 0.972 0.028
E77.1 Defects in glycoprotein degradation
0.000 0.972 0.028
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.972 0.028
D86.3 Sarcoidosis of skin
0.000 0.972 0.028
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.972 0.027
E83.5 Disorders of calcium metabolism
0.000 0.973 0.027
D89.1 Cryoglobulinaemia
0.000 0.973 0.027
E27 Other disorders of adrenal gland
0.000 0.973 0.027
D81 Combined immunodeficiencies
0.000 0.973 0.027
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.973 0.027
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.973 0.027
E70.2 Disorders of tyrosine metabolism
0.000 0.973 0.027
E70.1 Other hyperphenylalaninaemias
0.000 0.973 0.027
E70.0 Classical phenylketonuria
0.000 0.973 0.027
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.973 0.027
D83.9 Common variable immunodeficiency, unspecified
0.000 0.973 0.027
J45 Asthma
0.000 0.973 0.027
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.973 0.026
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.974 0.026
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.026 0.974 0.000
E34 Other endocrine disorders
0.000 0.974 0.026
E70.3 Albinism
0.000 0.974 0.026
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.974 0.026
B37.8 Candidiasis of other sites
0.000 0.974 0.026
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.974 0.026
E31 Polyglandular dysfunction
0.000 0.974 0.025
E28 Ovarian dysfunction
0.000 0.974 0.025
D82 Immunodeficiency associated with other major defects
0.000 0.974 0.025
R36 Urethral discharge
0.025 0.975 0.000
D84.1 Defects in the complement system
0.000 0.975 0.025
E80.6 Other disorders of bilirubin metabolism
0.000 0.975 0.025
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.975 0.025
E30 Disorders of puberty, not elsewhere classified
0.000 0.975 0.025
D89.3 Immune reconstitution syndrome
0.000 0.975 0.025
K35-K38 Diseases of appendix
0.000 0.975 0.025
D86.1 Sarcoidosis of lymph nodes
0.000 0.975 0.024
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.975 0.024
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.975 0.024
E79.1 Lesch-Nyhan syndrome
0.000 0.975 0.024
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.976 0.024
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.976 0.024
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.976 0.024
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.976 0.024
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.976 0.024
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.976 0.024
K70.4 Alcoholic hepatic failure
0.000 0.976 0.024
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.976 0.024
E80.5 Crigler-Najjar syndrome
0.000 0.976 0.024
E80.3 Defects of catalase and peroxydase
0.000 0.976 0.024
E80.0 Hereditary erythropoietic porphyria
0.000 0.976 0.024
E89.3 Postprocedural hypopituitarism
0.000 0.976 0.024
E32 Diseases of thymus
0.000 0.976 0.024
E28.3 Primary ovarian failure
0.000 0.976 0.024
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.976 0.023
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.976 0.023
E72.5 Disorders of glycine metabolism
0.000 0.976 0.023
E72.4 Disorders of ornithine metabolism
0.000 0.976 0.023
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.976 0.023
E72.2 Disorders of urea cycle metabolism
0.000 0.976 0.023
K74 Fibrosis and cirrhosis of liver
0.000 0.977 0.023
E34.8 Other specified endocrine disorders
0.000 0.977 0.023
E80.4 Gilbert's syndrome
0.000 0.977 0.023
E24 Cushing's syndrome
0.000 0.977 0.023
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.001 0.977 0.022
D86.8 Sarcoidosis of other and combined sites
0.000 0.977 0.023
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.977 0.023
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.977 0.023
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.977 0.022
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.977 0.022
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.977 0.022
E74.2 Disorders of galactose metabolism
0.000 0.977 0.022
E74.1 Disorders of fructose metabolism
0.000 0.977 0.022
E74.0 Glycogen storage disease
0.000 0.977 0.022
E80.1 Porphyria cutanea tarda
0.000 0.977 0.022
D83.8 Other common variable immunodeficiencies
0.000 0.977 0.022
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.977 0.022
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.977 0.022

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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