TreeWAS – Variant ID: rs3116788

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.002	0.998
L40 Psoriasis	0.000	0.006	0.994
L40.5 Arthropathic psoriasis	0.000	0.008	0.992
E10.1 With ketoacidosis	0.000	0.009	0.991
E10.3 With ophthalmic complications	0.000	0.025	0.975
E10.0 With coma	0.000	0.120	0.880
G35 Multiple sclerosis	0.832	0.168	0.000
L40.8 Other psoriasis	0.000	0.203	0.796
E10.2 With renal complications	0.000	0.222	0.778
L40.0 Psoriasis vulgaris	0.000	0.232	0.768
E10.6 With other specified complications	0.000	0.272	0.728
L40.2 Acrodermatitis continua	0.000	0.287	0.713
L40.1 Generalised pustular psoriasis	0.000	0.287	0.713
E10.8 With unspecified complications	0.000	0.320	0.680
E10.7 With multiple complications	0.000	0.345	0.655
L40.3 Pustulosis palmaris et plantaris	0.000	0.359	0.641
L40.4 Guttate psoriasis	0.000	0.360	0.639
E10.4 With neurological complications	0.000	0.370	0.630
E10.5 With peripheral circulatory complications	0.000	0.386	0.614
K90 Intestinal malabsorption	0.000	0.513	0.487
G35-G37 Demyelinating diseases of the central nervous system	0.438	0.562	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.605	0.395
K90.8 Other intestinal malabsorption	0.000	0.641	0.359
K90.3 Pancreatic steatorrhoea	0.000	0.650	0.350
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.650	0.350
K90.1 Tropical sprue	0.000	0.650	0.350
G37 Other demyelinating diseases of central nervous system	0.348	0.652	0.000
G36 Other acute disseminated demyelination	0.327	0.673	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.695	0.305
G37.9 Demyelinating disease of central nervous system, unspecified	0.302	0.698	0.000
E83 Disorders of mineral metabolism	0.293	0.707	0.000
E83.3 Disorders of phosphorus metabolism	0.256	0.744	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.254	0.746	0.000
G37.5 Concentric sclerosis [Balo]	0.250	0.750	0.000
G37.4 Subacute necrotising myelitis	0.250	0.750	0.000
G37.2 Central pontine myelinolysis	0.250	0.750	0.000
G37.1 Central demyelination of corpus callosum	0.250	0.750	0.000
G37.0 Diffuse sclerosis	0.250	0.750	0.000
E10-E14 Diabetes mellitus	0.001	0.750	0.249
G36.0 Neuromyelitis optica [Devic]	0.247	0.752	0.000
L40-L45 Papulosquamous disorders	0.012	0.760	0.227
G36.9 Acute disseminated demyelination, unspecified	0.235	0.765	0.000
G36.8 Other specified acute disseminated demyelination	0.235	0.765	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.235	0.765	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.221	0.779	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.210	0.790	0.000
E83.8 Other disorders of mineral metabolism	0.210	0.790	0.000
E83.2 Disorders of zinc metabolism	0.210	0.790	0.000
E83.0 Disorders of copper metabolism	0.210	0.790	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.206	0.794	0.000
E14 Unspecified diabetes mellitus	0.000	0.803	0.197
I71 Aortic aneurysm and dissection	0.188	0.812	0.000
E12 Malnutrition-related diabetes mellitus	0.001	0.821	0.179
I71.3 Abdominal aortic aneurysm, ruptured	0.173	0.827	0.000
L44 Other papulosquamous disorders	0.009	0.828	0.163
L41 Parapsoriasis	0.009	0.828	0.163
L45 Papulosquamous disorders in diseases classified elsewhere	0.009	0.828	0.163
L42 Pityriasis rosea	0.008	0.832	0.160
M06.9 Rheumatoid arthritis, unspecified	0.000	0.833	0.167
E14.3 With ophthalmic complications	0.000	0.833	0.167
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.836	0.164
I71.0 Dissection of aorta [any part]	0.164	0.836	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.837	0.163
E14.4 With neurological complications	0.000	0.839	0.160
E13 Other specified diabetes mellitus	0.001	0.843	0.156
E14.5 With peripheral circulatory complications	0.000	0.844	0.156
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.851	0.149
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.852	0.148
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.853	0.147
I71.1 Thoracic aortic aneurysm, ruptured	0.144	0.856	0.000
E14.1 With ketoacidosis	0.000	0.856	0.144
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.858	0.142
E14.7 With multiple complications	0.000	0.859	0.141
E14.2 Withrenal complications	0.000	0.859	0.141
E14.0 With coma	0.000	0.859	0.141
E14.8 With unspecified complications	0.000	0.859	0.141
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.141	0.859	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.135	0.865	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.135	0.865	0.000
E14.6 With other specified complications	0.000	0.868	0.132
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.129	0.871	0.000
E12.9 Without complications	0.001	0.871	0.128
E12.8 With unspecified complications	0.001	0.871	0.128
E12.7 With multiple complications	0.001	0.871	0.128
E12.6 With other specified complications	0.001	0.871	0.128
E12.5 With peripheral circulatory complications	0.001	0.871	0.128
E12.4 With neurological complications	0.001	0.871	0.128
E12.3 With ophthalmic complications	0.001	0.871	0.128
E12.2 With renal complications	0.001	0.871	0.128
E12.1 With ketoacidosis	0.001	0.871	0.128
E12.0 With coma	0.001	0.871	0.128
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.873	0.127
L41.9 Parapsoriasis, unspecified	0.007	0.876	0.117
L41.8 Other parapsoriasis	0.007	0.876	0.117
L41.5 Retiform parapsoriasis	0.007	0.876	0.117
L41.4 Large plaque parapsoriasis	0.007	0.876	0.117
L41.3 Small plaque parapsoriasis	0.007	0.876	0.117
L41.2 Lymphomatoid papulosis	0.007	0.876	0.117
L41.1 Pityriasis lichenoides chronica	0.007	0.876	0.117
L41.0 Pityriasis lichenoides et varioliformis acuta	0.007	0.876	0.117
L44.9 Papulosquamous disorder, unspecified	0.007	0.876	0.117
L44.8 Other specified papulosquamous disorders	0.007	0.876	0.117
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.007	0.876	0.117
L44.3 Lichen ruber moniliformis	0.007	0.876	0.117
L44.2 Lichen striatus	0.007	0.876	0.117
L44.1 Lichen nitidus	0.007	0.876	0.117
L44.0 Pityriasis rubra pilaris	0.007	0.876	0.117
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.118	0.882	0.000
E83.5 Disorders of calcium metabolism	0.116	0.884	0.000
E13.3 With ophthalmic complications	0.000	0.885	0.114
E13.8 With unspecified complications	0.001	0.888	0.112
E13.7 With multiple complications	0.001	0.888	0.112
E13.6 With other specified complications	0.001	0.888	0.112
E13.5 With peripheral circulatory complications	0.001	0.888	0.112
E13.4 With neurological complications	0.001	0.888	0.112
E13.2 With renal complications	0.001	0.888	0.112
E13.1 With ketoacidosis	0.001	0.888	0.112
E13.0 With coma	0.001	0.888	0.112
L43 Lichen planus	0.041	0.888	0.071
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.892	0.108
E89.0 Postprocedural hypothyroidism	0.106	0.894	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.895	0.105
N13 Obstructive and reflux uropathy	0.000	0.895	0.105
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.898	0.102
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.100	0.899	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.900	0.100
E89.2 Postprocedural hypoparathyroidism	0.091	0.909	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.910	0.090
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.911	0.089
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.911	0.089
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.088	0.912	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.914	0.086
E83.4 Disorders of magnesium metabolism	0.085	0.914	0.000
E13.9 Without complications	0.000	0.914	0.085
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.916	0.084
L43.3 Subacute (active) lichen planus	0.030	0.919	0.051
L43.2 Lichenoid drug reaction	0.030	0.919	0.051
L43.1 Bullous lichen planus	0.030	0.919	0.051
L43.0 Hypertrophic lichen planus	0.030	0.919	0.051
E89.4 Postprocedural ovarian failure	0.080	0.920	0.000
E70-E90 Metabolic disorders	0.079	0.920	0.001
E89.1 Postprocedural hypoinsulinaemia	0.077	0.922	0.000
M06 Other rheumatoid arthritis	0.000	0.926	0.074
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.072	0.928	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.072	0.928	0.000
E89.5 Postprocedural testicular hypofunction	0.072	0.928	0.000
L43.8 Other lichen planus	0.033	0.928	0.039
L43.9 Lichen planus, unspecified	0.068	0.930	0.002
E14.9 Without complications	0.000	0.933	0.067
N13.6 Pyonephrosis	0.000	0.938	0.062
E84 Cystic fibrosis	0.060	0.939	0.001
C73 Malignant neoplasm of thyroid gland	0.061	0.939	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.941	0.059
E74 Other disorders of carbohydrate metabolism	0.059	0.941	0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.058	0.941	0.001
M06.3 Rheumatoid nodule	0.000	0.941	0.059
E77 Disorders of glycoprotein metabolism	0.057	0.942	0.001
E76 Disorders of glycosaminoglycan metabolism	0.057	0.942	0.001
E72 Other disorders of amino-acid metabolism	0.057	0.942	0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.057	0.942	0.001
E70 Disorders of aromatic amino-acid metabolism	0.057	0.942	0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.057	0.942	0.001
N13.3 Other and unspecified hydronephrosis	0.000	0.946	0.054
M06.8 Other specified rheumatoid arthritis	0.000	0.947	0.053
M06.2 Rheumatoid bursitis	0.000	0.947	0.053
M06.1 Adult-onset Still's disease	0.000	0.947	0.053
E79 Disorders of purine and pyrimidine metabolism	0.053	0.947	0.001
Chapter IV Endocrine, nutritional and metabolic diseases	0.008	0.947	0.045
E11.0 With coma	0.000	0.948	0.052
E11.6 With other specified complications	0.000	0.949	0.051
M06.4 Inflammatory polyarthropathy	0.000	0.950	0.050
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.950	0.050
E73 Lactose intolerance	0.049	0.951	0.001
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.004	0.952	0.045
E84.9 Cystic fibrosis, unspecified	0.047	0.952	0.001
E80 Disorders of porphyrin and bilirubin metabolism	0.046	0.954	0.001
E21.3 Hyperparathyroidism, unspecified	0.000	0.954	0.046
E16 Other disorders of pancreatic internal secretion	0.001	0.954	0.045
E11.8 With unspecified complications	0.000	0.955	0.045
E74.3 Other disorders of intestinal carbohydrate absorption	0.044	0.955	0.000
K90-K93 Other diseases of the digestive system	0.000	0.956	0.044
E84.8 Cystic fibrosis with other manifestations	0.043	0.956	0.001
E84.1 Cystic fibrosis with intestinal manifestations	0.043	0.956	0.001
E84.0 Cystic fibrosis with pulmonary manifestations	0.043	0.956	0.001
E75.5 Other lipid storage disorders	0.043	0.956	0.001
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.957	0.043
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.957	0.043
E16.2 Hypoglycaemia, unspecified	0.000	0.957	0.043
E11.7 With multiple complications	0.000	0.957	0.043
E74.9 Disorder of carbohydrate metabolism, unspecified	0.042	0.957	0.001
E74.8 Other specified disorders of carbohydrate metabolism	0.042	0.957	0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.042	0.957	0.001
E74.2 Disorders of galactose metabolism	0.042	0.957	0.001
E74.1 Disorders of fructose metabolism	0.042	0.957	0.001
E74.0 Glycogen storage disease	0.042	0.957	0.001
E75.6 Lipid storage disorder, unspecified	0.042	0.957	0.001
E75.4 Neuronal ceroid lipofuscinosis	0.042	0.957	0.001
E75.3 Sphingolipidosis, unspecified	0.042	0.957	0.001
E75.2 Other sphingolipidosis	0.042	0.957	0.001
E75.1 Other gangliosidosis	0.042	0.957	0.001
E75.0 GM2 gangliosidosis	0.042	0.957	0.001
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.958	0.042
M06.38 Rheumatoid nodule (Other)	0.000	0.958	0.042
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.958	0.042
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.958	0.042
M06.33 Rheumatoid nodule (Forearm)	0.000	0.958	0.042
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.958	0.042
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.041	0.958	0.001
E70.8 Other disorders of aromatic amino-acid metabolism	0.041	0.958	0.001
E70.3 Albinism	0.041	0.958	0.001
E70.2 Disorders of tyrosine metabolism	0.041	0.958	0.001
E70.1 Other hyperphenylalaninaemias	0.041	0.958	0.001
E70.0 Classical phenylketonuria	0.041	0.958	0.001
E71.3 Disorders of fatty-acid metabolism	0.041	0.958	0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.041	0.958	0.001
E71.1 Other disorders of branched-chain amino-acid metabolism	0.041	0.958	0.001
E71.0 Maple-syrup-urine disease	0.041	0.958	0.001
E72.9 Disorder of amino-acid metabolism, unspecified	0.041	0.958	0.001
E72.8 Other specified disorders of amino-acid metabolism	0.041	0.958	0.001
E72.5 Disorders of glycine metabolism	0.041	0.958	0.001
E72.4 Disorders of ornithine metabolism	0.041	0.958	0.001
E72.3 Disorders of lysine and hydroxylysine metabolism	0.041	0.958	0.001
E72.2 Disorders of urea cycle metabolism	0.041	0.958	0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.041	0.958	0.001
E72.0 Disorders of amino-acid transport	0.041	0.958	0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.041	0.958	0.001
E76.8 Other disorders of glucosaminoglycan metabolism	0.041	0.958	0.001
E76.3 Mucopolysaccharidosis, unspecified	0.041	0.958	0.001
E76.2 Other mucopolysaccharidoses	0.041	0.958	0.001
E76.1 Mucopolysaccharidosis, type II	0.041	0.958	0.001
E76.0 Mucopolysaccharidosis, type I	0.041	0.958	0.001
E77.9 Disorder of glycoprotein metabolism, unspecified	0.041	0.958	0.001
E77.8 Other disorders of glycoprotein metabolism	0.041	0.958	0.001
E77.1 Defects in glycoprotein degradation	0.041	0.958	0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.041	0.958	0.001
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.960	0.040
E11.2 With renal complications	0.000	0.961	0.039
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.961	0.039
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.961	0.038
M06.18 Adult-onset Still's disease (Other)	0.000	0.961	0.038
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.961	0.038
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.961	0.038
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.961	0.038
M06.14 Adult-onset Still's disease (Hand)	0.000	0.961	0.038
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.961	0.038
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.961	0.038
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.961	0.038
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.961	0.038
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.961	0.038
M06.28 Rheumatoid bursitis (Other)	0.000	0.961	0.038
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.961	0.038
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.961	0.038
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.961	0.038
M06.24 Rheumatoid bursitis (Hand)	0.000	0.961	0.038
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.961	0.038
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.961	0.038
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.961	0.038
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.961	0.038
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.961	0.038
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.961	0.038
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.961	0.038
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.961	0.038
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.961	0.038
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.961	0.038
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.961	0.038
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.961	0.038
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.961	0.038
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.961	0.038
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.038	0.961	0.001
E79.8 Other disorders of purine and pyrimidine metabolism	0.038	0.961	0.001
E79.1 Lesch-Nyhan syndrome	0.038	0.961	0.001
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.962	0.038
E16.1 Other hypoglycaemia	0.000	0.962	0.038
N13.8 Other obstructive and reflux uropathy	0.000	0.962	0.038
E20-E35 Disorders of other endocrine glands	0.000	0.962	0.038
M06.0 Seronegative rheumatoid arthritis	0.000	0.962	0.038
E80.1 Porphyria cutanea tarda	0.037	0.962	0.001
E11.1 With ketoacidosis	0.000	0.963	0.037
E11.4 With neurological complications	0.000	0.963	0.037
N10-N16 Renal tubulo-interstitial diseases	0.000	0.963	0.037
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.964	0.036
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.964	0.036
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.964	0.036
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.964	0.036
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.964	0.036
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.964	0.036
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.964	0.036
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.964	0.036
E73.8 Other lactose intolerance	0.035	0.964	0.001
E73.1 Secondary lactase deficiency	0.035	0.964	0.001
E73.0 Congenital lactase deficiency	0.035	0.964	0.001
E50-E64 Other nutritional deficiencies	0.003	0.964	0.033
M06.34 Rheumatoid nodule (Hand)	0.000	0.964	0.035
E80.6 Other disorders of bilirubin metabolism	0.035	0.965	0.001
E15 Nondiabetic hypoglycaemic coma	0.003	0.965	0.032
E88 Other metabolic disorders	0.034	0.965	0.001
N13.4 Hydroureter	0.000	0.965	0.035
E89.3 Postprocedural hypopituitarism	0.034	0.965	0.001
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.034	0.965	0.001
N11 Chronic tubulo-interstitial nephritis	0.000	0.966	0.034
E80.7 Disorder of bilirubin metabolism, unspecified	0.033	0.966	0.001
E80.5 Crigler-Najjar syndrome	0.033	0.966	0.001
E80.3 Defects of catalase and peroxydase	0.033	0.966	0.001
E80.0 Hereditary erythropoietic porphyria	0.033	0.966	0.001
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.967	0.033
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.967	0.033
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.967	0.033
E16.4 Abnormal secretion of gastrin	0.001	0.967	0.033
E16.3 Increased secretion of glucagon	0.001	0.967	0.033
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.968	0.032
E80.2 Other porphyria	0.032	0.968	0.001
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.968	0.032
E61 Deficiency of other nutrient elements	0.001	0.968	0.031
E24 Cushing's syndrome	0.000	0.968	0.032
M07.3 Other psoriatic arthropathies	0.000	0.968	0.032
M07 Psoriatic and enteropathic arthropathies	0.000	0.969	0.031
M05-M14 Inflammatory polyarthropathies	0.000	0.969	0.031
E40-E46 Malnutrition	0.007	0.970	0.024
E28 Ovarian dysfunction	0.000	0.970	0.030
E21.0 Primary hyperparathyroidism	0.000	0.970	0.030
E61.1 Iron deficiency	0.000	0.970	0.029
E85 Amyloidosis	0.028	0.971	0.001
E21.4 Other specified disorders of parathyroid gland	0.000	0.971	0.029
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.971	0.029
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.972	0.028
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.972	0.028
E11.5 With peripheral circulatory complications	0.000	0.972	0.028
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.972	0.028
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.972	0.028
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.972	0.027
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.973	0.027
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.973	0.027
E32 Diseases of thymus	0.000	0.973	0.027
E31 Polyglandular dysfunction	0.000	0.973	0.027
E30 Disorders of puberty, not elsewhere classified	0.000	0.973	0.027
E73.9 Lactose intolerance, unspecified	0.027	0.973	0.001
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.973	0.027
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.973	0.027
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.973	0.027
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.973	0.027
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.973	0.027
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.973	0.027
E29 Testicular dysfunction	0.000	0.973	0.027
E25 Adrenogenital disorders	0.000	0.973	0.026
N11.1 Chronic obstructive pyelonephritis	0.000	0.973	0.027
I70-I79 Diseases of arteries, arterioles and capillaries	0.026	0.974	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.974	0.026
E88.3 Tumour lysis syndrome	0.026	0.974	0.001
E28.2 Polycystic ovarian syndrome	0.000	0.974	0.026
E21.2 Other hyperparathyroidism	0.000	0.974	0.026
N15 Other renal tubulo-interstitial diseases	0.000	0.974	0.026
E24.0 Pituitary-dependent Cushing's disease	0.000	0.974	0.026
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.974	0.024
E63 Other nutritional deficiencies	0.002	0.974	0.024
E56 Other vitamin deficiencies	0.002	0.974	0.024
E50 Vitamin A deficiency	0.002	0.974	0.024
E60 Dietary zinc deficiency	0.002	0.974	0.024
E59 Dietary selenium deficiency	0.002	0.974	0.024
E54 Ascorbic acid deficiency	0.002	0.974	0.024
E52 Niacin deficiency [pellagra]	0.002	0.974	0.024
E88.9 Metabolic disorder, unspecified	0.025	0.974	0.001
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.026	0.974	0.000
E51 Thiamine deficiency	0.002	0.974	0.024
M12 Other specific arthropathies	0.000	0.975	0.025
E24.2 Drug-induced Cushing's syndrome	0.000	0.975	0.025
I72 Other aneurysm	0.025	0.975	0.000
E61.2 Magnesium deficiency	0.001	0.975	0.024
E88.1 Lipodystrophy, not elsewhere classified	0.024	0.975	0.001
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.975	0.025
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.975	0.025
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.975	0.025
I72.4 Aneurysm of artery of lower extremity	0.024	0.975	0.000
E88.8 Other specified metabolic disorders	0.023	0.976	0.001
E20 Hypoparathyroidism	0.000	0.976	0.023
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.977	0.023
K93.1 Megacolon in Chagas' disease	0.000	0.977	0.023
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.977	0.023
I70 Atherosclerosis	0.023	0.977	0.000
E61.9 Deficiency of nutrient element, unspecified	0.001	0.977	0.022
E61.8 Deficiency of other specified nutrient elements	0.001	0.977	0.022
E61.7 Deficiency of multiple nutrient elements	0.001	0.977	0.022
E61.6 Vanadium deficiency	0.001	0.977	0.022
E61.5 Molybdenum deficiency	0.001	0.977	0.022
E61.4 Chromium deficiency	0.001	0.977	0.022
E61.3 Manganese deficiency	0.001	0.977	0.022
E61.0 Copper deficiency	0.001	0.977	0.022
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.977	0.023
E58 Dietary calcium deficiency	0.002	0.977	0.021
M11 Other crystal arthropathies	0.000	0.977	0.023
E24.8 Other Cushing's syndrome	0.000	0.977	0.023
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.977	0.023
E24.3 Ectopic ACTH syndrome	0.000	0.977	0.023
E24.1 Nelson's syndrome	0.000	0.977	0.023
E24.9 Cushing's syndrome, unspecified	0.000	0.977	0.023
M07.38 Other psoriatic arthropathies (Other)	0.000	0.977	0.023
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.977	0.023
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.977	0.023
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.977	0.023
E34 Other endocrine disorders	0.000	0.977	0.023
E88.2 Lipomatosis, not elsewhere classified	0.022	0.977	0.001
E55 Vitamin D deficiency	0.001	0.977	0.021
M07.5 Arthropathy in ulcerative colitis	0.000	0.978	0.022
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.978	0.022
M07.2 Psoriatic spondylitis	0.000	0.978	0.022
M07.1 Arthritis mutilans	0.000	0.978	0.022
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.978	0.022
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.978	0.022
E44 Protein-energy malnutrition of moderate and mild degree	0.005	0.978	0.017
E45 Retarded development following protein-energy malnutrition	0.005	0.978	0.017
E43 Unspecified severe protein-energy malnutrition	0.005	0.978	0.017
E42 Marasmic kwashiorkor	0.005	0.978	0.017
E41 Nutritional marasmus	0.005	0.978	0.017
E40 Kwashiorkor	0.005	0.978	0.017
E28.9 Ovarian dysfunction, unspecified	0.000	0.978	0.022
E28.8 Other ovarian dysfunction	0.000	0.978	0.022
E28.1 Androgen excess	0.000	0.978	0.022
E28.0 Oestrogen excess	0.000	0.978	0.022
M07.6 Other enteropathic arthropathies	0.000	0.978	0.022
I70.2 Atherosclerosis of arteries of the extremities	0.022	0.978	0.000
M08 Juvenile arthritis	0.000	0.978	0.021
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.978	0.021
E85.2 Heredofamilial amyloidosis, unspecified	0.020	0.979	0.001
E85.1 Neuropathic heredofamilial amyloidosis	0.020	0.979	0.001
E85.0 Nonneuropathic heredofamilial amyloidosis	0.020	0.979	0.001
E85.8 Other amyloidosis	0.020	0.979	0.001
E22 Hyperfunction of pituitary gland	0.000	0.979	0.021
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.979	0.021
E85.3 Secondary systemic amyloidosis	0.019	0.980	0.001
M12.3 Palindromic rheumatism	0.000	0.980	0.020
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.980	0.020
N14.3 Nephropathy induced by heavy metals	0.000	0.980	0.020
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.980	0.020
N14.0 Analgesic nephropathy	0.000	0.980	0.020
E23 Hypofunction and other disorders of pituitary gland	0.000	0.980	0.020
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.020	0.980	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.980	0.020
N15.1 Renal and perinephric abscess	0.000	0.980	0.020
E30.9 Disorder of puberty, unspecified	0.000	0.980	0.020
E30.8 Other disorders of puberty	0.000	0.980	0.020
E30.1 Precocious puberty	0.000	0.980	0.020
E30.0 Delayed puberty	0.000	0.980	0.020
E31.9 Polyglandular dysfunction, unspecified	0.000	0.980	0.020
E31.8 Other polyglandular dysfunction	0.000	0.980	0.020
E31.1 Polyglandular hyperfunction	0.000	0.980	0.020
E31.0 Autoimmune polyglandular failure	0.000	0.980	0.020
E32.9 Disease of thymus, unspecified	0.000	0.980	0.020
E32.8 Other diseases of thymus	0.000	0.980	0.020
E32.1 Abscess of thymus	0.000	0.980	0.020
E32.0 Persistent hyperplasia of thymus	0.000	0.980	0.020
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.980	0.020
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.980	0.020
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.980	0.020
M12.2 Villonodular synovitis (pigmented)	0.000	0.980	0.020
E26 Hyperaldosteronism	0.001	0.980	0.019
M14 Arthropathies in other diseases classified elsewhere	0.000	0.980	0.020
E29.9 Testicular dysfunction, unspecified	0.000	0.980	0.020
E29.8 Other testicular dysfunction	0.000	0.980	0.020
E29.0 Testicular hyperfunction	0.000	0.980	0.020
E29.1 Testicular hypofunction	0.000	0.980	0.019
E25.9 Adrenogenital disorder, unspecified	0.000	0.981	0.019
E25.8 Other adrenogenital disorders	0.000	0.981	0.019
I72.0 Aneurysm of carotid artery	0.019	0.981	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.981	0.019
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.981	0.019
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.981	0.019
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.981	0.019
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.981	0.019
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.981	0.019
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.981	0.019
C74 Malignant neoplasm of adrenal gland	0.019	0.981	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.981	0.019
N15.0 Balkan nephropathy	0.000	0.981	0.019
I72.9 Aneurysm of unspecified site	0.019	0.981	0.000
E28.3 Primary ovarian failure	0.000	0.981	0.019
E50.9 Vitamin A deficiency, unspecified	0.002	0.981	0.017
E50.8 Other manifestations of vitamin A deficiency	0.002	0.981	0.017
E50.7 Other ocular manifestations of vitamin A deficiency	0.002	0.981	0.017
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.002	0.981	0.017
E50.5 Vitamin A deficiency with night blindness	0.002	0.981	0.017
E50.4 Vitamin A deficiency with keratomalacia	0.002	0.981	0.017
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.002	0.981	0.017
E50.2 Vitamin A deficiency with corneal xerosis	0.002	0.981	0.017
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.002	0.981	0.017
E50.0 Vitamin A deficiency with conjunctival xerosis	0.002	0.981	0.017
E56.9 Vitamin deficiency, unspecified	0.002	0.981	0.017
E56.8 Deficiency of other vitamins	0.002	0.981	0.017
E56.1 Deficiency of vitamin K	0.002	0.981	0.017
E56.0 Deficiency of vitamin E	0.002	0.981	0.017
E63.9 Nutritional deficiency, unspecified	0.002	0.981	0.017
E63.8 Other specified nutritional deficiencies	0.002	0.981	0.017
E63.1 Imbalance of constituents of food intake	0.002	0.981	0.017
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.981	0.017
E64.9 Sequelae of unspecified nutritional deficiency	0.002	0.981	0.017
E64.8 Sequelae of other nutritional deficiencies	0.002	0.981	0.017
E64.3 Sequelae of rickets	0.002	0.981	0.017
E64.2 Sequelae of vitamin C deficiency	0.002	0.981	0.017

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations