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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3117073
log Bayes Factor = 35.6695
Chromosome 6   position 29,544,825  (GRCh37) Explore rs3117073 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.025 0.975
E10.3 With ophthalmic complications
0.000 0.039 0.961
E10.9 Without complications
0.000 0.059 0.941
E10.2 With renal complications
0.000 0.075 0.925
E10.4 With neurological complications
0.000 0.077 0.923
E10-E14 Diabetes mellitus
0.000 0.121 0.879
E10.1 With ketoacidosis
0.000 0.134 0.866
E13 Other specified diabetes mellitus
0.000 0.138 0.861
E10.6 With other specified complications
0.000 0.147 0.853
E13.9 Without complications
0.000 0.151 0.849
E10.0 With coma
0.000 0.193 0.807
E10.5 With peripheral circulatory complications
0.000 0.298 0.702
E10.7 With multiple complications
0.000 0.301 0.699
E12 Malnutrition-related diabetes mellitus
0.000 0.370 0.630
E13.8 With unspecified complications
0.000 0.382 0.618
E13.7 With multiple complications
0.000 0.382 0.618
E13.6 With other specified complications
0.000 0.382 0.618
E13.5 With peripheral circulatory complications
0.000 0.382 0.618
E13.4 With neurological complications
0.000 0.382 0.618
E13.3 With ophthalmic complications
0.000 0.382 0.618
E13.2 With renal complications
0.000 0.382 0.618
E13.1 With ketoacidosis
0.000 0.382 0.618
E13.0 With coma
0.000 0.382 0.618
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.453 0.547
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.466 0.534
E14 Unspecified diabetes mellitus
0.000 0.468 0.532
E16 Other disorders of pancreatic internal secretion
0.000 0.476 0.524
E20-E35 Disorders of other endocrine glands
0.000 0.478 0.522
E10.8 With unspecified complications
0.000 0.479 0.521
E23 Hypofunction and other disorders of pituitary gland
0.000 0.482 0.518
E16.2 Hypoglycaemia, unspecified
0.000 0.483 0.517
E23.0 Hypopituitarism
0.000 0.491 0.509
E24 Cushing's syndrome
0.000 0.515 0.485
E23.2 Diabetes insipidus
0.000 0.543 0.457
E24.9 Cushing's syndrome, unspecified
0.000 0.545 0.455
E12.9 Without complications
0.000 0.548 0.452
E12.8 With unspecified complications
0.000 0.548 0.452
E12.7 With multiple complications
0.000 0.548 0.452
E12.6 With other specified complications
0.000 0.548 0.452
E12.5 With peripheral circulatory complications
0.000 0.548 0.452
E12.4 With neurological complications
0.000 0.548 0.452
E12.3 With ophthalmic complications
0.000 0.548 0.452
E12.2 With renal complications
0.000 0.548 0.452
E12.1 With ketoacidosis
0.000 0.548 0.452
E12.0 With coma
0.000 0.548 0.452
E16.1 Other hypoglycaemia
0.000 0.562 0.438
E14.1 With ketoacidosis
0.000 0.589 0.411
E14.6 With other specified complications
0.000 0.589 0.411
K90 Intestinal malabsorption
0.000 0.600 0.400
E14.4 With neurological complications
0.000 0.601 0.398
E22 Hyperfunction of pituitary gland
0.000 0.617 0.383
E15 Nondiabetic hypoglycaemic coma
0.000 0.617 0.383
E14.7 With multiple complications
0.000 0.618 0.382
E14.5 With peripheral circulatory complications
0.000 0.618 0.382
E14.0 With coma
0.000 0.618 0.382
E23.7 Disorder of pituitary gland, unspecified
0.000 0.623 0.376
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.624 0.376
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.624 0.376
E16.4 Abnormal secretion of gastrin
0.000 0.624 0.376
E16.3 Increased secretion of glucagon
0.000 0.624 0.376
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.626 0.374
E32 Diseases of thymus
0.000 0.626 0.374
E30 Disorders of puberty, not elsewhere classified
0.000 0.626 0.374
E14.2 Withrenal complications
0.000 0.627 0.373
E20 Hypoparathyroidism
0.000 0.628 0.372
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.628 0.372
E23.1 Drug-induced hypopituitarism
0.000 0.628 0.372
E25 Adrenogenital disorders
0.000 0.629 0.371
E23.6 Other disorders of pituitary gland
0.000 0.631 0.369
E11 Non-insulin-dependent diabetes mellitus
0.000 0.633 0.367
E24.2 Drug-induced Cushing's syndrome
0.000 0.638 0.361
E14.8 With unspecified complications
0.000 0.643 0.357
E14.3 With ophthalmic complications
0.000 0.645 0.355
E34 Other endocrine disorders
0.000 0.648 0.352
E24.8 Other Cushing's syndrome
0.000 0.652 0.348
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.652 0.348
E24.3 Ectopic ACTH syndrome
0.000 0.652 0.348
E24.1 Nelson's syndrome
0.000 0.652 0.348
E24.0 Pituitary-dependent Cushing's disease
0.000 0.652 0.348
E26 Hyperaldosteronism
0.000 0.662 0.337
E31 Polyglandular dysfunction
0.000 0.663 0.337
E29 Testicular dysfunction
0.000 0.669 0.331
E11.6 With other specified complications
0.000 0.677 0.323
E50-E64 Other nutritional deficiencies
0.000 0.678 0.322
E00-E07 Disorders of thyroid gland
0.000 0.686 0.314
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.693 0.307
E27 Other disorders of adrenal gland
0.000 0.695 0.305
E40-E46 Malnutrition
0.000 0.696 0.303
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.702 0.298
E11.2 With renal complications
0.000 0.703 0.297
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.706 0.293
E22.0 Acromegaly and pituitary gigantism
0.000 0.708 0.292
E28 Ovarian dysfunction
0.000 0.711 0.289
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.712 0.288
K90.3 Pancreatic steatorrhoea
0.000 0.713 0.287
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.713 0.287
K90.1 Tropical sprue
0.000 0.713 0.287
K90.8 Other intestinal malabsorption
0.000 0.713 0.287
E11.0 With coma
0.000 0.719 0.281
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.721 0.279
E11.1 With ketoacidosis
0.000 0.724 0.276
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.725 0.275
E22.8 Other hyperfunction of pituitary gland
0.000 0.725 0.275
E11.8 With unspecified complications
0.000 0.726 0.274
E34.9 Endocrine disorder, unspecified
0.000 0.731 0.269
E30.9 Disorder of puberty, unspecified
0.000 0.731 0.268
E30.8 Other disorders of puberty
0.000 0.731 0.268
E30.1 Precocious puberty
0.000 0.731 0.268
E30.0 Delayed puberty
0.000 0.731 0.268
E32.9 Disease of thymus, unspecified
0.000 0.731 0.268
E32.8 Other diseases of thymus
0.000 0.731 0.268
E32.1 Abscess of thymus
0.000 0.731 0.268
E32.0 Persistent hyperplasia of thymus
0.000 0.731 0.268
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.731 0.268
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.731 0.268
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.731 0.268
E34.8 Other specified endocrine disorders
0.000 0.732 0.268
E20.8 Other hypoparathyroidism
0.000 0.733 0.267
E20.1 Pseudohypoparathyroidism
0.000 0.733 0.267
E20.0 Idiopathic hypoparathyroidism
0.000 0.733 0.267
E25.9 Adrenogenital disorder, unspecified
0.000 0.734 0.266
E25.8 Other adrenogenital disorders
0.000 0.734 0.266
E20.9 Hypoparathyroidism, unspecified
0.000 0.736 0.264
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.737 0.263
E11.7 With multiple complications
0.000 0.737 0.263
E05.9 Thyrotoxicosis, unspecified
0.000 0.746 0.254
E34.5 Androgen resistance syndrome
0.000 0.747 0.252
E34.4 Constitutional tall stature
0.000 0.747 0.252
E34.3 Short stature, not elsewhere classified
0.000 0.747 0.252
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.747 0.252
E34.1 Other hypersecretion of intestinal hormones
0.000 0.747 0.252
E22.1 Hyperprolactinaemia
0.000 0.752 0.248
E05.8 Other thyrotoxicosis
0.000 0.754 0.245
K90.9 Intestinal malabsorption, unspecified
0.000 0.757 0.243
E26.9 Hyperaldosteronism, unspecified
0.000 0.758 0.242
E26.8 Other hyperaldosteronism
0.000 0.758 0.242
E26.1 Secondary hyperaldosteronism
0.000 0.758 0.242
E31.9 Polyglandular dysfunction, unspecified
0.000 0.758 0.241
E31.8 Other polyglandular dysfunction
0.000 0.758 0.241
E31.1 Polyglandular hyperfunction
0.000 0.758 0.241
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.758 0.242
E11.5 With peripheral circulatory complications
0.000 0.761 0.239
E29.9 Testicular dysfunction, unspecified
0.000 0.763 0.237
E29.8 Other testicular dysfunction
0.000 0.763 0.237
E29.0 Testicular hyperfunction
0.000 0.763 0.237
E14.9 Without complications
0.000 0.764 0.236
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.769 0.231
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.769 0.231
E63 Other nutritional deficiencies
0.000 0.769 0.231
E56 Other vitamin deficiencies
0.000 0.769 0.231
E50 Vitamin A deficiency
0.000 0.769 0.231
E60 Dietary zinc deficiency
0.000 0.769 0.231
E59 Dietary selenium deficiency
0.000 0.769 0.231
E54 Ascorbic acid deficiency
0.000 0.769 0.231
E52 Niacin deficiency [pellagra]
0.000 0.769 0.231
E51 Thiamine deficiency
0.000 0.773 0.227
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.774 0.225
E00 Congenital iodine-deficiency syndrome
0.000 0.774 0.225
E61 Deficiency of other nutrient elements
0.000 0.775 0.224
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.778 0.222
E55 Vitamin D deficiency
0.000 0.779 0.221
E58 Dietary calcium deficiency
0.000 0.781 0.219
E27.5 Adrenomedullary hyperfunction
0.000 0.781 0.218
E27.0 Other adrenocortical overactivity
0.000 0.781 0.218
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.782 0.218
E45 Retarded development following protein-energy malnutrition
0.000 0.782 0.218
E43 Unspecified severe protein-energy malnutrition
0.000 0.782 0.218
E42 Marasmic kwashiorkor
0.000 0.782 0.218
E41 Nutritional marasmus
0.000 0.782 0.218
E40 Kwashiorkor
0.000 0.782 0.218
E05.5 Thyroid crisis or storm
0.000 0.786 0.214
E05.4 Thyrotoxicosis factitia
0.000 0.786 0.214
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.786 0.214
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.786 0.214
E27.9 Disorder of adrenal gland, unspecified
0.000 0.786 0.214
E28.3 Primary ovarian failure
0.000 0.789 0.211
E27.8 Other specified disorders of adrenal gland
0.000 0.790 0.210
E28.9 Ovarian dysfunction, unspecified
0.000 0.793 0.207
E28.8 Other ovarian dysfunction
0.000 0.793 0.207
E28.1 Androgen excess
0.000 0.793 0.207
E28.0 Oestrogen excess
0.000 0.793 0.207
E53 Deficiency of other B group vitamins
0.000 0.794 0.206
E26.0 Primary hyperaldosteronism
0.000 0.795 0.205
E65-E68 Obesity and other hyperalimentation
0.000 0.795 0.205
E27.1 Primary adrenocortical insufficiency
0.000 0.796 0.204
E31.0 Autoimmune polyglandular failure
0.000 0.796 0.204
E29.1 Testicular hypofunction
0.000 0.807 0.193
E34.0 Carcinoid syndrome
0.000 0.822 0.177
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.823 0.177
E50.9 Vitamin A deficiency, unspecified
0.000 0.834 0.166
E50.8 Other manifestations of vitamin A deficiency
0.000 0.834 0.166
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.834 0.166
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.834 0.166
E50.5 Vitamin A deficiency with night blindness
0.000 0.834 0.166
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.834 0.166
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.834 0.166
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.834 0.166
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.834 0.166
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.834 0.166
E56.9 Vitamin deficiency, unspecified
0.000 0.834 0.166
E56.8 Deficiency of other vitamins
0.000 0.834 0.166
E56.1 Deficiency of vitamin K
0.000 0.834 0.166
E56.0 Deficiency of vitamin E
0.000 0.834 0.166
E63.9 Nutritional deficiency, unspecified
0.000 0.834 0.166
E63.8 Other specified nutritional deficiencies
0.000 0.834 0.166
E63.1 Imbalance of constituents of food intake
0.000 0.834 0.166
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.834 0.166
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.834 0.166
E64.8 Sequelae of other nutritional deficiencies
0.000 0.834 0.166
E64.3 Sequelae of rickets
0.000 0.834 0.166
E64.2 Sequelae of vitamin C deficiency
0.000 0.834 0.166
E64.1 Sequelae of vitamin A deficiency
0.000 0.834 0.166
E64.0 Sequelae of protein-energy malnutrition
0.000 0.834 0.166
E53.9 Vitamin B deficiency, unspecified
0.000 0.835 0.165
E27.2 Addisonian crisis
0.000 0.836 0.164
E06 Thyroiditis
0.000 0.837 0.163
E51.9 Thiamine deficiency, unspecified
0.000 0.837 0.163
E51.8 Other manifestations of thiamine deficiency
0.000 0.837 0.163
E51.1 Beriberi
0.000 0.837 0.163
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.838 0.162
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.838 0.162
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.838 0.162
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.838 0.162
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.838 0.162
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.838 0.162
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.838 0.162
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.838 0.162
E03 Other hypothyroidism
0.000 0.838 0.162
E07 Other disorders of thyroid
0.000 0.838 0.162
E61.9 Deficiency of nutrient element, unspecified
0.000 0.839 0.161
E61.8 Deficiency of other specified nutrient elements
0.000 0.839 0.161
E61.7 Deficiency of multiple nutrient elements
0.000 0.839 0.161
E61.6 Vanadium deficiency
0.000 0.839 0.161
E61.5 Molybdenum deficiency
0.000 0.839 0.161
E61.4 Chromium deficiency
0.000 0.839 0.161
E61.3 Manganese deficiency
0.000 0.839 0.161
E61.0 Copper deficiency
0.000 0.839 0.161
E51.2 Wernicke's encephalopathy
0.000 0.841 0.158
E55.0 Rickets, active
0.000 0.841 0.158
E61.1 Iron deficiency
0.000 0.842 0.158
E61.2 Magnesium deficiency
0.000 0.842 0.158
E44.1 Mild protein-energy malnutrition
0.000 0.844 0.156
E44.0 Moderate protein-energy malnutrition
0.000 0.844 0.156
E11.4 With neurological complications
0.000 0.847 0.153
E55.9 Vitamin D deficiency, unspecified
0.000 0.852 0.148
E53.1 Pyridoxine deficiency
0.000 0.852 0.148
E53.0 Riboflavin deficiency
0.000 0.852 0.148
E67 Other hyperalimentation
0.000 0.853 0.147
E68 Sequelae of hyperalimentation
0.000 0.853 0.147
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.857 0.143
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.857 0.143
K51 Ulcerative colitis
0.142 0.858 0.000
K51.9 Ulcerative colitis, unspecified
0.139 0.861 0.000
K51.4 Pseudopolyposis of colon
0.138 0.862 0.000
E03.8 Other specified hypothyroidism
0.000 0.867 0.133
E06.9 Thyroiditis, unspecified
0.000 0.871 0.129
E46 Unspecified protein-energy malnutrition
0.000 0.871 0.128
E83 Disorders of mineral metabolism
0.128 0.872 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.873 0.127
K51.3 Ulcerative (chronic) rectosigmoiditis
0.125 0.875 0.000
K51.5 Mucosal proctocolitis
0.120 0.880 0.000
E07.8 Other specified disorders of thyroid
0.000 0.882 0.118
E21.2 Other hyperparathyroidism
0.000 0.882 0.117
E06.4 Drug-induced thyroiditis
0.000 0.883 0.117
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.883 0.117
E06.1 Subacute thyroiditis
0.000 0.883 0.117
E06.0 Acute thyroiditis
0.000 0.883 0.117
E03.5 Myxoedema coma
0.000 0.884 0.116
E03.4 Atrophy of thyroid (acquired)
0.000 0.884 0.116
E03.3 Postinfectious hypothyroidism
0.000 0.884 0.116
E03.1 Congenital hypothyroidism without goitre
0.000 0.884 0.116
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.884 0.116
E07.1 Dyshormogenetic goitre
0.000 0.884 0.116
E07.0 Hypersecretion of calcitonin
0.000 0.884 0.116
K51.8 Other ulcerative colitis
0.115 0.885 0.000
E65 Localised adiposity
0.000 0.885 0.115
E28.2 Polycystic ovarian syndrome
0.000 0.887 0.113
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.887 0.113
K51.2 Ulcerative (chronic) proctitis
0.108 0.892 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.107 0.893 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.893 0.107
E06.5 Other chronic thyroiditis
0.000 0.894 0.106
E67.8 Other specified hyperalimentation
0.000 0.894 0.106
E67.3 Hypervitaminosis D
0.000 0.894 0.106
E67.2 Megavitamin-B6 syndrome
0.000 0.894 0.106
E67.1 Hypercarotenaemia
0.000 0.894 0.106
E67.0 Hypervitaminosis A
0.000 0.894 0.106
E21.3 Hyperparathyroidism, unspecified
0.000 0.896 0.103
K51.0 Ulcerative (chronic) enterocolitis
0.098 0.901 0.000
E04 Other non-toxic goitre
0.000 0.902 0.098
E83.9 Disorder of mineral metabolism, unspecified
0.092 0.908 0.000
E83.8 Other disorders of mineral metabolism
0.092 0.908 0.000
E83.2 Disorders of zinc metabolism
0.092 0.908 0.000
E83.0 Disorders of copper metabolism
0.092 0.908 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.910 0.090
K50-K52 Noninfective enteritis and colitis
0.089 0.911 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.912 0.088
K50 Crohn's disease [regional enteritis]
0.086 0.914 0.000
E83.3 Disorders of phosphorus metabolism
0.084 0.916 0.000
K50.9 Crohn's disease, unspecified
0.084 0.916 0.000
E11.9 Without complications
0.000 0.917 0.083
E83.4 Disorders of magnesium metabolism
0.076 0.923 0.000
E11.3 With ophthalmic complications
0.000 0.925 0.075
K50.1 Crohn's disease of large intestine
0.075 0.925 0.000
E04.8 Other specified non-toxic goitre
0.000 0.930 0.070
K50.0 Crohn's disease of small intestine
0.059 0.941 0.000
K50.8 Other Crohn's disease
0.056 0.944 0.000
C43.5 Malignant melanoma of trunk
0.000 0.947 0.053
E04.0 Non-toxic diffuse goitre
0.000 0.948 0.051
E07.9 Disorder of thyroid, unspecified
0.000 0.953 0.047
E66 Obesity
0.000 0.953 0.047
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.954 0.046
C43 Malignant melanoma of skin
0.000 0.954 0.046
E06.3 Autoimmune thyroiditis
0.001 0.956 0.044
C43.4 Malignant melanoma of scalp and neck
0.000 0.961 0.039
C43.9 Malignant melanoma of skin, unspecified
0.000 0.962 0.038
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.962 0.038
E66.1 Drug-induced obesity
0.000 0.966 0.034
E66.8 Other obesity
0.000 0.966 0.034
C77.2 Intra-abdominal lymph nodes
0.033 0.967 0.000
C43.8 Overlapping malignant melanoma of skin
0.000 0.967 0.033
C43.0 Malignant melanoma of lip
0.000 0.967 0.033
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.971 0.029
E66.0 Obesity due to excess calories
0.000 0.972 0.027
E21.0 Primary hyperparathyroidism
0.000 0.974 0.025
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.975 0.025
K90-K93 Other diseases of the digestive system
0.000 0.977 0.023
E83.5 Disorders of calcium metabolism
0.023 0.977 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.978 0.022
L30.9 Dermatitis, unspecified
0.022 0.978 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.979 0.021
V18.0 Driver injured in nontraffic accident
0.019 0.981 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.981 0.019
H54.0 Blindness, both eyes
0.000 0.983 0.017
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.983 0.017
A08.4 Viral intestinal infection, unspecified
0.000 0.983 0.017
E04.1 Non-toxic single thyroid nodule
0.000 0.984 0.016
H54 Blindness and low vision
0.000 0.984 0.016
C18.0 Caecum
0.015 0.985 0.000
H54.7 Unspecified visual loss
0.000 0.985 0.015
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.985 0.015
H54.9 Unspecified visual impairment (binocular)
0.000 0.987 0.013
H54.6 Unqualified visual loss, one eye
0.000 0.987 0.013
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.988 0.012
K93.1 Megacolon in Chagas' disease
0.000 0.988 0.012
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.988 0.012
H54.4 Blindness, one eye
0.000 0.988 0.012
H54.5 Low vision, one eye
0.000 0.988 0.012
H54.3 Unqualified visual loss, both eyes
0.000 0.989 0.011
L30 Other dermatitis
0.011 0.989 0.000
K04.5 Chronic apical periodontitis
0.011 0.989 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.011 0.989 0.000
Q21 Congenital malformations of cardiac septa
0.011 0.989 0.000
I78.1 Naevus, nonneoplastic
0.011 0.989 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.989 0.011
C18.2 Ascending colon
0.011 0.989 0.000
Q21.0 Ventricular septal defect
0.011 0.989 0.000
Q23 Congenital malformations of aortic and mitral valves
0.011 0.989 0.000
C18.5 Splenic flexure
0.010 0.990 0.000
K52 Other non-infective gastro-enteritis and colitis
0.010 0.990 0.000
H54.2 Low vision, both eyes
0.000 0.990 0.010
S62.3 Fracture of other metacarpal bone
0.000 0.990 0.010
C18 Malignant neoplasm of colon
0.010 0.990 0.000
Q28 Other congenital malformations of circulatory system
0.010 0.990 0.000
H54.1 Blindness, one eye, low vision, other eye
0.000 0.990 0.010
Q23.0 Congenital stenosis of aortic valve
0.009 0.990 0.000
Q26 Congenital malformations of great veins
0.009 0.991 0.000
Q21.3 Tetralogy of Fallot
0.009 0.991 0.000
Q25 Congenital malformations of great arteries
0.009 0.991 0.000
H40.2 Primary angle-closure glaucoma
0.009 0.991 0.000
Q23.1 Congenital insufficiency of aortic valve
0.009 0.991 0.000
L30.4 Erythema intertrigo
0.009 0.991 0.000
Q27 Other congenital malformations of peripheral vascular system
0.009 0.991 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.009 0.991 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.009 0.991 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.009 0.991 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.009 0.991 0.000
S61.8 Open wound of other parts of wrist and hand
0.009 0.991 0.000
L30.1 Dyshidrosis [pompholyx]
0.008 0.991 0.000
L30.8 Other specified dermatitis
0.008 0.991 0.000
L30.3 Infective dermatitis
0.008 0.991 0.000
Q24 Other congenital malformations of heart
0.008 0.991 0.000
L30.5 Pityriasis alba
0.008 0.992 0.000
L30.2 Cutaneous autosensitisation
0.008 0.992 0.000
L30.0 Nummular dermatitis
0.008 0.992 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.008 0.992 0.000
Q21.1 Atrial septal defect
0.008 0.992 0.000
Q21.8 Other congenital malformations of cardiac septa
0.008 0.992 0.000
Q21.4 Aortopulmonary septal defect
0.008 0.992 0.000
Q21.2 Atrioventricular septal defect
0.008 0.992 0.000
C18.3 Hepatic flexure
0.008 0.992 0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified
0.008 0.992 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.008 0.992 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.008 0.992 0.000
Q23.4 Hypoplastic left heart syndrome
0.008 0.992 0.000
Q23.3 Congenital mitral insufficiency
0.008 0.992 0.000
Q23.2 Congenital mitral stenosis
0.008 0.992 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.992 0.008
Q28.0 Arteriovenous malformation of precerebral vessels
0.008 0.992 0.000
S62.31 Fracture of other metacarpal bone (open)
0.000 0.992 0.008
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.008 0.992 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.008 0.992 0.000
C18.8 Overlapping lesion of colon
0.007 0.992 0.000
Q28.9 Congenital malformation of circulatory system, unspecified
0.007 0.993 0.000
Q28.8 Other specified congenital malformations of circulatory system
0.007 0.993 0.000
Q28.1 Other malformations of precerebral vessels
0.007 0.993 0.000
Q28.3 Other malformations of cerebral vessels
0.007 0.993 0.000
L03.1 Cellulitis of other parts of limb
0.007 0.993 0.000
Q25.1 Coarctation of aorta
0.007 0.993 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.007 0.993 0.000
Q25.6 Stenosis of pulmonary artery
0.007 0.993 0.000
Q25.4 Other congenital malformations of aorta
0.007 0.993 0.000
Q24.8 Other specified congenital malformations of heart
0.007 0.993 0.000
Q26.9 Congenital malformation of great vein, unspecified
0.007 0.993 0.000
Q26.8 Other congenital malformations of great veins
0.007 0.993 0.000
Q26.6 Portal vein-hepatic artery fistula
0.007 0.993 0.000
Q26.5 Anomalous portal venous connexion
0.007 0.993 0.000
Q26.3 Partial anomalous pulmonary venous connexion
0.007 0.993 0.000
Q26.2 Total anomalous pulmonary venous connexion
0.007 0.993 0.000
Q26.1 Persistent left superior vena cava
0.007 0.993 0.000
Q26.0 Congenital stenosis of vena cava
0.007 0.993 0.000
Q25.0 Patent ductus arteriosus
0.007 0.993 0.000
Q22.5 Ebstein's anomaly
0.007 0.993 0.000
Q25.9 Congenital malformation of great arteries, unspecified
0.007 0.993 0.000
Q25.8 Other congenital malformations of great arteries
0.007 0.993 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.007 0.993 0.000
Q25.5 Atresia of pulmonary artery
0.007 0.993 0.000
Q25.3 Stenosis of aorta
0.007 0.993 0.000
Q25.2 Atresia of aorta
0.007 0.993 0.000
C18.4 Transverse colon
0.007 0.993 0.000
Q24.0 Dextrocardia
0.007 0.993 0.000
Q27.3 Peripheral arteriovenous malformation
0.007 0.993 0.000
Q83 Congenital malformations of breast
0.007 0.993 0.000
Q27.4 Congenital phlebectasia
0.006 0.993 0.000
Q27.2 Other congenital malformations of renal artery
0.006 0.993 0.000
Q27.1 Congenital renal artery stenosis
0.006 0.993 0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.006 0.993 0.000
Q24.5 Malformation of coronary vessels
0.006 0.993 0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified
0.006 0.993 0.000
Q22.8 Other congenital malformations of tricuspid valve
0.006 0.993 0.000
Q22.6 Hypoplastic right heart syndrome
0.006 0.993 0.000
Q22.4 Congenital tricuspid stenosis
0.006 0.993 0.000
Q22.3 Other congenital malformations of pulmonary valve
0.006 0.993 0.000
Q22.2 Congenital pulmonary valve insufficiency
0.006 0.993 0.000
Q22.1 Congenital pulmonary valve stenosis
0.006 0.993 0.000
Q22.0 Pulmonary valve atresia
0.006 0.993 0.000
Q24.6 Congenital heart block
0.006 0.994 0.000
Q24.4 Congenital subaortic stenosis
0.006 0.994 0.000
Q24.3 Pulmonary infundibular stenosis
0.006 0.994 0.000
Q24.2 Cor triatriatum
0.006 0.994 0.000
Q24.1 Levocardia
0.006 0.994 0.000
Q83.1 Accessory breast
0.006 0.994 0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified
0.006 0.994 0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions
0.006 0.994 0.000
Q20.6 Isomerism of atrial appendages
0.006 0.994 0.000
Q20.5 Discordant atrioventricular connexion
0.006 0.994 0.000
Q20.4 Double inlet ventricle
0.006 0.994 0.000
Q20.3 Discordant ventriculoarterial connexion
0.006 0.994 0.000
Q20.2 Double outlet left ventricle
0.006 0.994 0.000
Q20.1 Double outlet right ventricle
0.006 0.994 0.000
Q20.0 Common arterial trunk
0.006 0.994 0.000
Q80-Q89 Other congenital malformations
0.006 0.994 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.006 0.994 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.006 0.994 0.000
Q89 Other congenital malformations, not elsewhere classified
0.006 0.994 0.000
V18.5 Passenger injured in traffic accident
0.006 0.994 0.000
V18.1 Passenger injured in nontraffic accident
0.006 0.994 0.000
Q83.8 Other congenital malformations of breast
0.006 0.994 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.006 0.994 0.000
H40.5 Glaucoma secondary to other eye disorders
0.006 0.994 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.006 0.994 0.000
V18.4 Driver injured in traffic accident
0.006 0.994 0.000
Q83.3 Accessory nipple
0.006 0.994 0.000
Q89.2 Congenital malformations of other endocrine glands
0.006 0.994 0.000
K52.1 Toxic gastro-enteritis and colitis
0.005 0.994 0.000
K52.3 Indeterminate colitis
0.005 0.994 0.000
C18.1 Appendix
0.005 0.994 0.000
E70-E90 Metabolic disorders
0.004 0.995 0.001
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified
0.005 0.995 0.000
V18.3 Person injured while boarding or alighting
0.005 0.995 0.000
I78 Diseases of capillaries
0.005 0.995 0.000
Q83.9 Congenital malformation of breast, unspecified
0.005 0.995 0.000
Q83.2 Absent nipple
0.005 0.995 0.000
Q83.0 Congenital absence of breast with absent nipple
0.005 0.995 0.000
H40 Glaucoma
0.005 0.995 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.000 0.995 0.005
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.005 0.995 0.000
Q89.3 Situs inversus
0.005 0.995 0.000
I78.8 Other diseases of capillaries
0.005 0.995 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.005 0.995 0.000
Q84 Other congenital malformations of integument
0.005 0.995 0.000
Q81 Epidermolysis bullosa
0.005 0.995 0.000
Q80 Congenital ichthyosis
0.005 0.995 0.000
M89.8 Other specified disorders of bone
0.000 0.995 0.005
C18.7 Sigmoid colon
0.005 0.995 0.000
Q87.4 Marfan's syndrome
0.005 0.995 0.000
H53-H54 Visual disturbances and blindness
0.000 0.995 0.005
Q85 Phakomatoses, not elsewhere classified
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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