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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3117119
log Bayes Factor = 184.849
Chromosome 6   position 32,318,610  (GRCh37) Explore rs3117119 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.001 0.999
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.003 0.997
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.996 0.004 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.006 0.994
J33 Nasal polyp
0.000 0.009 0.991
E14.3 With ophthalmic complications
0.000 0.011 0.989
J33.9 Nasal polyp, unspecified
0.000 0.013 0.987
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.014 0.986
K51.8 Other ulcerative colitis
0.986 0.014 0.000
J33.0 Polyp of nasal cavity
0.000 0.014 0.986
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.015 0.985
H36 Retinal disorders in diseases classified elsewhere
0.000 0.016 0.984
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.017 0.983
J33.8 Other polyp of sinus
0.000 0.021 0.979
E70-E90 Metabolic disorders
0.000 0.021 0.978
E11.1 With ketoacidosis
0.000 0.022 0.978
H30-H36 Disorders of choroid and retina
0.000 0.027 0.973
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.028 0.972
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.034 0.966
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.038 0.962
K51.2 Ulcerative (chronic) proctitis
0.958 0.042 0.000
E10.5 With peripheral circulatory complications
0.000 0.042 0.958
K90 Intestinal malabsorption
0.000 0.047 0.953
Chapter VII Diseases of the eye and adnexa
0.000 0.048 0.952
E11.3 With ophthalmic complications
0.000 0.053 0.947
# Top node
0.000 0.054 0.946
Chapter XI Diseases of the digestive system
0.000 0.055 0.945
K90-K93 Other diseases of the digestive system
0.000 0.056 0.944
H43-H45 Disorders of vitreous body and globe
0.000 0.058 0.942
K70-K77 Diseases of liver
0.000 0.058 0.942
J45 Asthma
0.000 0.059 0.941
H43 Disorders of vitreous body
0.000 0.060 0.940
E10.2 With renal complications
0.000 0.065 0.935
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.070 0.930
K74 Fibrosis and cirrhosis of liver
0.000 0.071 0.929
E05.9 Thyrotoxicosis, unspecified
0.000 0.072 0.928
J40-J47 Chronic lower respiratory diseases
0.000 0.074 0.926
E06 Thyroiditis
0.000 0.075 0.925
H43.3 Other vitreous opacities
0.000 0.080 0.920
K74.3 Primary biliary cirrhosis
0.000 0.080 0.920
E11.5 With peripheral circulatory complications
0.000 0.081 0.919
Chapter X Diseases of the respiratory system
0.000 0.081 0.919
H40-H42 Glaucoma
0.000 0.081 0.919
E13 Other specified diabetes mellitus
0.000 0.082 0.917
M07 Psoriatic and enteropathic arthropathies
0.000 0.084 0.916
H34 Retinal vascular occlusions
0.000 0.096 0.904
H40 Glaucoma
0.000 0.105 0.895
H40.9 Glaucoma, unspecified
0.000 0.110 0.890
K50-K52 Noninfective enteritis and colitis
0.021 0.112 0.867
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.115 0.885
J30-J39 Other diseases of upper respiratory tract
0.000 0.121 0.879
E06.3 Autoimmune thyroiditis
0.000 0.122 0.878
E03.8 Other specified hypothyroidism
0.000 0.125 0.875
H43.8 Other disorders of vitreous body
0.000 0.126 0.874
G37.8 Other specified demyelinating diseases of central nervous system
0.871 0.129 0.000
J43 Emphysema
0.000 0.132 0.868
M06.4 Inflammatory polyarthropathy
0.000 0.139 0.861
E13.9 Without complications
0.000 0.142 0.858
M07.3 Other psoriatic arthropathies
0.000 0.144 0.856
E11.2 With renal complications
0.000 0.146 0.854
E78.1 Pure hyperglyceridaemia
0.000 0.149 0.851
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.152 0.848
E07 Other disorders of thyroid
0.000 0.156 0.844
K72 Hepatic failure, not elsewhere classified
0.000 0.157 0.843
K76 Other diseases of liver
0.000 0.170 0.830
M06.3 Rheumatoid nodule
0.000 0.172 0.828
K76.8 Other specified diseases of liver
0.000 0.174 0.826
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.174 0.825
I10 Essential (primary) hypertension
0.000 0.178 0.822
I10-I15 Hypertensive diseases
0.000 0.180 0.820
K51.5 Mucosal proctocolitis
0.819 0.181 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.812 0.188 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.190 0.810
E40-E46 Malnutrition
0.000 0.193 0.807
K50 Crohn's disease [regional enteritis]
0.001 0.194 0.805
K51.4 Pseudopolyposis of colon
0.797 0.203 0.000
J43.9 Emphysema, unspecified
0.000 0.206 0.794
E11.6 With other specified complications
0.000 0.207 0.793
Chapter IX Diseases of the circulatory system
0.000 0.208 0.792
M06.0 Seronegative rheumatoid arthritis
0.000 0.209 0.791
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.210 0.790
E11.8 With unspecified complications
0.000 0.213 0.787
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.213 0.787
H34.2 Other retinal artery occlusions
0.000 0.215 0.785
H40.1 Primary open-angle glaucoma
0.000 0.218 0.782
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.219 0.781
K55-K64 Other diseases of intestines
0.000 0.219 0.781
J46 Status asthmaticus
0.000 0.222 0.778
E88 Other metabolic disorders
0.000 0.223 0.777
M14 Arthropathies in other diseases classified elsewhere
0.000 0.227 0.773
I12 Hypertensive renal disease
0.000 0.228 0.772
K60 Fissure and fistula of anal and rectal regions
0.000 0.231 0.769
J44 Other chronic obstructive pulmonary disease
0.000 0.231 0.769
H34.8 Other retinal vascular occlusions
0.000 0.231 0.769
M65-M68 Disorders of synovium and tendon
0.000 0.233 0.767
E16.1 Other hypoglycaemia
0.000 0.236 0.764
H43.9 Disorder of vitreous body, unspecified
0.000 0.239 0.761
L40.5 Arthropathic psoriasis
0.000 0.242 0.758
E74 Other disorders of carbohydrate metabolism
0.000 0.242 0.758
K55 Vascular disorders of intestine
0.000 0.243 0.757
L40 Psoriasis
0.000 0.243 0.757
L40-L45 Papulosquamous disorders
0.000 0.245 0.755
E07.9 Disorder of thyroid, unspecified
0.000 0.247 0.753
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.250 0.750
K75 Other inflammatory liver diseases
0.000 0.251 0.749
K60.2 Anal fissure, unspecified
0.000 0.253 0.747
M45-M49 Spondylopathies
0.000 0.253 0.747
J86 Pyothorax
0.000 0.255 0.745
I20-I25 Ischaemic heart diseases
0.000 0.256 0.744
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.257 0.743
K74.5 Biliary cirrhosis, unspecified
0.000 0.259 0.741
H35 Other retinal disorders
0.000 0.259 0.741
K51.0 Ulcerative (chronic) enterocolitis
0.738 0.261 0.000
I22 Subsequent myocardial infarction
0.000 0.262 0.738
L43 Lichen planus
0.000 0.262 0.738
I12.9 Hypertensive renal disease without renal failure
0.000 0.263 0.737
K73 Chronic hepatitis, not elsewhere classified
0.000 0.265 0.735
M45 Ankylosing spondylitis
0.000 0.268 0.732
K55.2 Angiodysplasia of colon
0.000 0.269 0.731
K50.8 Other Crohn's disease
0.000 0.269 0.731
J43.2 Centrilobular emphysema
0.000 0.269 0.730
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.271 0.729
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.274 0.726
H43.1 Vitreous haemorrhage
0.000 0.275 0.725
L43.9 Lichen planus, unspecified
0.000 0.279 0.721
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.280 0.720
K74.6 Other and unspecified cirrhosis of liver
0.000 0.281 0.719
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
H30 Chorioretinal inflammation
0.000 0.283 0.717
Chapter VIII Diseases of the ear and mastoid process
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.715 0.284 0.000
G37.5 Concentric sclerosis [Balo]
0.715 0.285 0.000
G37.4 Subacute necrotising myelitis
0.715 0.285 0.000
G37.2 Central pontine myelinolysis
0.715 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.285 0.000
G37.0 Diffuse sclerosis
0.715 0.285 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.286 0.714
K50.1 Crohn's disease of large intestine
0.000 0.287 0.713
K72.9 Hepatic failure, unspecified
0.000 0.287 0.713
K72.0 Acute and subacute hepatic failure
0.000 0.287 0.713
J33.1 Polypoid sinus degeneration
0.000 0.289 0.710
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.291 0.709
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.294 0.706
E78.6 Lipoprotein deficiency
0.000 0.295 0.705
E78.3 Hyperchylomicronaemia
0.000 0.295 0.705
M86-M90 Other osteopathies
0.000 0.297 0.703
K60.5 Anorectal fistula
0.000 0.297 0.703
K60.0 Acute anal fissure
0.000 0.298 0.702
E77 Disorders of glycoprotein metabolism
0.000 0.298 0.701
E76 Disorders of glycosaminoglycan metabolism
0.000 0.298 0.701
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.298 0.701
E72 Other disorders of amino-acid metabolism
0.000 0.298 0.701
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.298 0.701
E70 Disorders of aromatic amino-acid metabolism
0.000 0.298 0.701
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.298 0.701
I15 Secondary hypertension
0.000 0.300 0.700
M06.34 Rheumatoid nodule (Hand)
0.000 0.300 0.700
K52 Other non-infective gastro-enteritis and colitis
0.005 0.300 0.695
M65 Synovitis and tenosynovitis
0.000 0.300 0.700
K51.1 Ulcerative (chronic) ileocolitis
0.699 0.301 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.301 0.699
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.302 0.698
H40.5 Glaucoma secondary to other eye disorders
0.000 0.302 0.698
H34.1 Central retinal artery occlusion
0.000 0.305 0.695
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.305 0.695
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.306 0.694
E83 Disorders of mineral metabolism
0.501 0.307 0.192
K75.4 Autoimmune hepatitis
0.000 0.309 0.691
E05.5 Thyroid crisis or storm
0.000 0.310 0.689
E05.4 Thyrotoxicosis factitia
0.000 0.310 0.689
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.310 0.689
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.310 0.689
H60-H62 Diseases of external ear
0.000 0.312 0.688
H43.2 Crystalline deposits in vitreous body
0.000 0.316 0.684
K90.3 Pancreatic steatorrhoea
0.000 0.317 0.683
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.317 0.683
K90.1 Tropical sprue
0.000 0.317 0.683
H40.4 Glaucoma secondary to eye inflammation
0.000 0.317 0.683
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.321 0.679
K55.8 Other vascular disorders of intestine
0.000 0.321 0.679
K58 Irritable bowel syndrome
0.000 0.322 0.678
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.322 0.678
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.323 0.677
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.324 0.675
K77 Liver disorders in diseases classified elsewhere
0.000 0.324 0.675
K71 Toxic liver disease
0.000 0.324 0.675
J45.1 Nonallergic asthma
0.000 0.325 0.675
H43.0 Vitreous prolapse
0.000 0.326 0.674
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.327 0.673
J37 Chronic laryngitis and laryngotracheitis
0.000 0.327 0.673
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.330 0.670
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.331 0.669
E46 Unspecified protein-energy malnutrition
0.000 0.331 0.669
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.332 0.668
H61 Other disorders of external ear
0.000 0.333 0.667
K74.4 Secondary biliary cirrhosis
0.000 0.334 0.666
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.334 0.666
K74.1 Hepatic sclerosis
0.000 0.334 0.666
E05.8 Other thyrotoxicosis
0.000 0.336 0.664
E06.5 Other chronic thyroiditis
0.000 0.337 0.663
E06.4 Drug-induced thyroiditis
0.000 0.337 0.663
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.337 0.663
E06.1 Subacute thyroiditis
0.000 0.337 0.663
E06.0 Acute thyroiditis
0.000 0.337 0.663
E79 Disorders of purine and pyrimidine metabolism
0.000 0.339 0.661
M12 Other specific arthropathies
0.000 0.339 0.660
H42 Glaucoma in diseases classified elsewhere
0.000 0.341 0.659
E13.8 With unspecified complications
0.000 0.342 0.658
E13.7 With multiple complications
0.000 0.342 0.658
E13.6 With other specified complications
0.000 0.342 0.658
E13.5 With peripheral circulatory complications
0.000 0.342 0.658
E13.4 With neurological complications
0.000 0.342 0.658
E13.3 With ophthalmic complications
0.000 0.342 0.658
E13.2 With renal complications
0.000 0.342 0.658
E13.1 With ketoacidosis
0.000 0.342 0.658
E13.0 With coma
0.000 0.342 0.658
M07.6 Other enteropathic arthropathies
0.000 0.343 0.657
M07.5 Arthropathy in ulcerative colitis
0.000 0.343 0.657
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.343 0.657
M07.2 Psoriatic spondylitis
0.000 0.343 0.657
M07.1 Arthritis mutilans
0.000 0.343 0.657
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.343 0.657
M14.6 Neuropathic arthropathy
0.000 0.345 0.655
H34.9 Retinal vascular occlusion, unspecified
0.000 0.346 0.653
M11 Other crystal arthropathies
0.000 0.346 0.653
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.347 0.653
H34.0 Transient retinal artery occlusion
0.000 0.352 0.648
J86.0 Pyothorax with fistula
0.000 0.352 0.648
E84 Cystic fibrosis
0.000 0.355 0.645
H40.6 Glaucoma secondary to drugs
0.000 0.358 0.642
H40.3 Glaucoma secondary to eye trauma
0.000 0.358 0.642
M88 Paget's disease of bone [osteitis deformans]
0.000 0.360 0.640
H35.6 Retinal haemorrhage
0.000 0.360 0.639
H35.4 Peripheral retinal degeneration
0.000 0.361 0.639
J95-J99 Other diseases of the respiratory system
0.000 0.362 0.638
J41 Simple and mucopurulent chronic bronchitis
0.000 0.362 0.638
E11.0 With coma
0.000 0.363 0.637
M70-M79 Other soft tissue disorders
0.000 0.366 0.634
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.366 0.634
M91-M94 Chondropathies
0.000 0.369 0.631
J85 Abscess of lung and mediastinum
0.000 0.370 0.630
E78.4 Other hyperlipidaemia
0.000 0.371 0.629
H61.0 Perichondritis of external ear
0.000 0.372 0.628
H25-H28 Disorders of lens
0.000 0.376 0.624
E88.2 Lipomatosis, not elsewhere classified
0.000 0.377 0.623
J43.8 Other emphysema
0.000 0.377 0.623
J43.1 Panlobular emphysema
0.000 0.377 0.623
J43.0 MacLeod's syndrome
0.000 0.377 0.623
E06.9 Thyroiditis, unspecified
0.000 0.379 0.621
J86.9 Pyothorax without fistula
0.000 0.379 0.621
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.381 0.619
K52.1 Toxic gastro-enteritis and colitis
0.002 0.382 0.616
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.383 0.617
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.383 0.617
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.383 0.617
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.383 0.617
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.383 0.617
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.383 0.617
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.383 0.617
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.383 0.617
J45.8 Mixed asthma
0.000 0.383 0.617
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.384 0.616
K76.7 Hepatorenal syndrome
0.000 0.385 0.615
M07.38 Other psoriatic arthropathies (Other)
0.000 0.386 0.614
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.386 0.614
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.386 0.614
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.386 0.614
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.386 0.614
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.386 0.614
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.386 0.614
K90.8 Other intestinal malabsorption
0.000 0.389 0.611
I11 Hypertensive heart disease
0.000 0.389 0.611
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.394 0.606
E07.1 Dyshormogenetic goitre
0.000 0.395 0.605
E07.0 Hypersecretion of calcitonin
0.000 0.395 0.605
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.395 0.605
K72.1 Chronic hepatic failure
0.000 0.395 0.604
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.396 0.604
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.399 0.601
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.399 0.601
K55.1 Chronic vascular disorders of intestine
0.000 0.399 0.601
H31 Other disorders of choroid
0.000 0.400 0.600
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.400 0.600
L40.9 Psoriasis, unspecified
0.000 0.402 0.598
E03.1 Congenital hypothyroidism without goitre
0.000 0.405 0.595
K76.5 Hepatic veno-occlusive disease
0.000 0.405 0.595
K76.4 Peliosis hepatis
0.000 0.405 0.595
K76.3 Infarction of liver
0.000 0.405 0.595
K76.2 Central haemorrhagic necrosis of liver
0.000 0.405 0.595
M88.9 Paget's disease of bone, unspecified
0.000 0.405 0.594
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.407 0.593
M06.38 Rheumatoid nodule (Other)
0.000 0.407 0.593
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.407 0.593
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.407 0.593
M06.33 Rheumatoid nodule (Forearm)
0.000 0.407 0.593
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.407 0.593
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.407 0.593
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.407 0.593
H33 Retinal detachments and breaks
0.000 0.408 0.592
I13 Hypertensive heart and renal disease
0.000 0.412 0.588
K90.9 Intestinal malabsorption, unspecified
0.000 0.412 0.588
K52.8 Other specified non-infective gastro-enteritis and colitis
0.001 0.412 0.587
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.413 0.587
E78.8 Other disorders of lipoprotein metabolism
0.000 0.413 0.586
H35.7 Separation of retinal layers
0.000 0.414 0.586
E85 Amyloidosis
0.000 0.415 0.585
E65-E68 Obesity and other hyperalimentation
0.000 0.415 0.585
L43.8 Other lichen planus
0.000 0.416 0.584
I15.1 Hypertension secondary to other renal disorders
0.000 0.417 0.583
L40.8 Other psoriasis
0.000 0.417 0.583
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.418 0.582
I24 Other acute ischaemic heart diseases
0.000 0.421 0.579
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.421 0.579
E45 Retarded development following protein-energy malnutrition
0.000 0.421 0.579
E43 Unspecified severe protein-energy malnutrition
0.000 0.421 0.579
E42 Marasmic kwashiorkor
0.000 0.421 0.579
E41 Nutritional marasmus
0.000 0.421 0.579
E40 Kwashiorkor
0.000 0.421 0.579
H35.2 Other proliferative retinopathy
0.000 0.423 0.577
E11.4 With neurological complications
0.000 0.425 0.575
K73.9 Chronic hepatitis, unspecified
0.000 0.427 0.573
H61.8 Other specified disorders of external ear
0.000 0.428 0.572
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.428 0.572
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.429 0.571
H61.1 Non-infective disorders of pinna
0.000 0.431 0.569
H35.5 Hereditary retinal dystrophy
0.000 0.431 0.568
I00-I02 Acute rheumatic fever
0.000 0.432 0.568
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.433 0.567
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.433 0.567
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.433 0.567
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.433 0.567
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.433 0.567
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.433 0.567
H27 Other disorders of lens
0.000 0.433 0.567
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.000 0.436 0.564
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.440 0.560
I12.0 Hypertensive renal disease with renal failure
0.000 0.442 0.558
E88.9 Metabolic disorder, unspecified
0.000 0.443 0.557
E88.8 Other specified metabolic disorders
0.000 0.443 0.557
E88.3 Tumour lysis syndrome
0.000 0.443 0.557
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.443 0.557
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.444 0.556
I15.9 Seconday hypertension, unspecified
0.000 0.445 0.555
M10 Gout
0.000 0.445 0.554
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.446 0.554
M14.4 Arthropathy in amyloidosis
0.000 0.446 0.554
M14.3 Lipoid dermatoarthritis
0.000 0.446 0.554
M14.2 Diabetic arthropathy
0.000 0.446 0.554
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.446 0.554
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.446 0.554
E07.8 Other specified disorders of thyroid
0.000 0.448 0.552
K50.0 Crohn's disease of small intestine
0.000 0.449 0.551
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.450 0.550
M86 Osteomyelitis
0.000 0.452 0.548
J32 Chronic sinusitis
0.000 0.455 0.545
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.455 0.544
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.456 0.543
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.456 0.543
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.456 0.543
E74.2 Disorders of galactose metabolism
0.000 0.456 0.543
E74.1 Disorders of fructose metabolism
0.000 0.456 0.543
E74.0 Glycogen storage disease
0.000 0.456 0.543
L40.4 Guttate psoriasis
0.000 0.457 0.543
L40.3 Pustulosis palmaris et plantaris
0.000 0.457 0.543
L40.2 Acrodermatitis continua
0.000 0.457 0.543
L40.1 Generalised pustular psoriasis
0.000 0.457 0.543
L44 Other papulosquamous disorders
0.000 0.459 0.541
L41 Parapsoriasis
0.000 0.459 0.541
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.459 0.541
M46 Other inflammatory spondylopathies
0.000 0.459 0.541
M49 Spondylopathies in diseases classified elsewhere
0.000 0.460 0.540
E73 Lactose intolerance
0.001 0.462 0.538
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.462 0.538
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.463 0.537
K75.2 Nonspecific reactive hepatitis
0.000 0.463 0.537
K75.1 Phlebitis of portal vein
0.000 0.463 0.537
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.464 0.536
M77 Other enthesopathies
0.000 0.465 0.535
H35.8 Other specified retinal disorders
0.000 0.467 0.533
H30.9 Chorioretinal inflammation, unspecified
0.000 0.467 0.533
H61.3 Acquired stenosis of external ear canal
0.000 0.468 0.532
H35.1 Retinopathy of prematurity
0.000 0.469 0.531
M66 Spontaneous rupture of synovium and tendon
0.000 0.469 0.531
L40.0 Psoriasis vulgaris
0.000 0.470 0.530
M00-M03 Infectious arthropathies
0.000 0.470 0.530
I23 Certain current complications following acute myocardial infarction
0.000 0.470 0.530
M65.1 Other infective (teno)synovitis
0.000 0.470 0.529
L43.3 Subacute (active) lichen planus
0.000 0.471 0.529
L43.2 Lichenoid drug reaction
0.000 0.471 0.529
L43.1 Bullous lichen planus
0.000 0.471 0.529
L43.0 Hypertrophic lichen planus
0.000 0.471 0.529
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.472 0.528
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.472 0.528
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.473 0.527
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.473 0.527
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.473 0.527
E78.5 Hyperlipidaemia, unspecified
0.000 0.474 0.526
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.474 0.526
H33.0 Retinal detachment with retinal break
0.000 0.475 0.525
J37.0 Chronic laryngitis
0.000 0.475 0.525
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.475 0.525
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.475 0.525
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.475 0.525
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.475 0.525
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.475 0.525
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.475 0.525
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.475 0.525
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.481 0.519
J85.2 Abscess of lung without pneumonia
0.000 0.481 0.519
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.481 0.519
M77.1 Lateral epicondylitis
0.000 0.484 0.516
M60-M63 Disorders of muscles
0.000 0.484 0.515
E83.9 Disorder of mineral metabolism, unspecified
0.396 0.485 0.120
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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