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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3117122
log Bayes Factor = 145.115
Chromosome 6   position 32,316,604  (GRCh37) Explore rs3117122 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
C83 Diffuse non-Hodgkin's lymphoma
1.000 0.000 0.000
C83.3 Large cell (diffuse)
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
1.000 0.000 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.999 0.001 0.000
E10.1 With ketoacidosis
0.989 0.011 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.989 0.011 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.988 0.012 0.000
E21.3 Hyperparathyroidism, unspecified
0.986 0.014 0.000
H00.1 Chalazion
0.000 0.015 0.985
M06.9 Rheumatoid arthritis, unspecified
0.000 0.018 0.982
L40.5 Arthropathic psoriasis
0.971 0.029 0.000
E11 Non-insulin-dependent diabetes mellitus
0.969 0.031 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.034 0.966
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.040 0.960
E10.4 With neurological complications
0.960 0.040 0.000
E11.3 With ophthalmic complications
0.959 0.041 0.000
L40 Psoriasis
0.957 0.043 0.000
E27 Other disorders of adrenal gland
0.956 0.044 0.000
L40-L45 Papulosquamous disorders
0.956 0.044 0.000
L43 Lichen planus
0.955 0.045 0.000
L43.9 Lichen planus, unspecified
0.955 0.045 0.000
J45.9 Asthma, unspecified
0.000 0.045 0.955
M06 Other rheumatoid arthritis
0.000 0.057 0.943
E27.1 Primary adrenocortical insufficiency
0.940 0.060 0.000
E28 Ovarian dysfunction
0.940 0.060 0.000
E10.2 With renal complications
0.921 0.079 0.000
C81 Hodgkin's disease
0.920 0.080 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.917 0.083 0.000
N00-N08 Glomerular diseases
0.915 0.085 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.914 0.086 0.000
M06.3 Rheumatoid nodule
0.000 0.088 0.912
N04 Nephrotic syndrome
0.911 0.089 0.000
E14 Unspecified diabetes mellitus
0.902 0.098 0.000
E11.1 With ketoacidosis
0.901 0.099 0.000
N04.9 Unspecified
0.901 0.099 0.000
N03 Chronic nephritic syndrome
0.899 0.101 0.000
C83.1 Small cleaved cell (diffuse)
0.897 0.103 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.890 0.110 0.000
E28.2 Polycystic ovarian syndrome
0.889 0.111 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.111 0.889
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.116 0.884
C85.1 B-cell lymphoma, unspecified
0.880 0.120 0.000
C81.1 Nodular sclerosis
0.876 0.124 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.129 0.871
E07 Other disorders of thyroid
0.871 0.129 0.000
N03.9 Unspecified
0.867 0.133 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.139 0.861
N05 Unspecified nephritic syndrome
0.860 0.140 0.000
E10.5 With peripheral circulatory complications
0.858 0.142 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.858 0.142 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.855 0.145 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.146 0.854
H00 Hordeolum and chalazion
0.026 0.147 0.827
E16 Other disorders of pancreatic internal secretion
0.853 0.147 0.000
C82.0 Small cleaved cell, follicular
0.850 0.150 0.000
H36.0 Diabetic retinopathy
0.849 0.151 0.000
E10.8 With unspecified complications
0.848 0.152 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.156 0.844
E03 Other hypothyroidism
0.844 0.156 0.000
E06 Thyroiditis
0.842 0.158 0.000
E10.7 With multiple complications
0.830 0.170 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.827 0.173 0.000
C84.5 Other and unspecified T-cell lymphomas
0.827 0.173 0.000
C82.2 Large cell, follicular
0.826 0.174 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.825 0.175 0.000
E16.2 Hypoglycaemia, unspecified
0.820 0.180 0.000
N05.2 Diffuse membranous glomerulonephritis
0.820 0.180 0.000
E23 Hypofunction and other disorders of pituitary gland
0.817 0.183 0.000
H36 Retinal disorders in diseases classified elsewhere
0.817 0.183 0.000
N18 Chronic renal failure
0.808 0.192 0.000
E07.8 Other specified disorders of thyroid
0.808 0.192 0.000
E34 Other endocrine disorders
0.802 0.198 0.000
C83.7 Burkitt's tumour
0.802 0.198 0.000
N18.4 Chronic kidney disease, stage 4
0.800 0.200 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.203 0.797
N18.9 Chronic renal failure, unspecified
0.797 0.203 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.796 0.204 0.000
Q60-Q64 Congenital malformations of the urinary system
0.796 0.204 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.794 0.206 0.000
Q61 Cystic kidney disease
0.794 0.206 0.000
H30-H36 Disorders of choroid and retina
0.793 0.207 0.000
# Top node
0.789 0.211 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.004 0.211 0.784
E27.8 Other specified disorders of adrenal gland
0.788 0.212 0.000
C91 Lymphoid leukaemia
0.787 0.213 0.000
N17-N19 Renal failure
0.787 0.213 0.000
H34 Retinal vascular occlusions
0.787 0.213 0.000
E26 Hyperaldosteronism
0.785 0.215 0.000
Chapter XIV Diseases of the genitourinary system
0.785 0.215 0.000
Q61.3 Polycystic kidney, unspecified
0.783 0.217 0.000
H34.8 Other retinal vascular occlusions
0.782 0.218 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.782 0.218 0.000
E11.5 With peripheral circulatory complications
0.781 0.219 0.000
E14.8 With unspecified complications
0.772 0.228 0.000
E06.3 Autoimmune thyroiditis
0.765 0.235 0.000
L40.3 Pustulosis palmaris et plantaris
0.762 0.238 0.000
N03.8 Other
0.762 0.238 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.239 0.761
E40-E46 Malnutrition
0.760 0.240 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.758 0.242 0.000
E11.2 With renal complications
0.756 0.244 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.245 0.754
E14.4 With neurological complications
0.754 0.246 0.000
N04.1 Focal and segmental glomerular lesions
0.752 0.248 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.751 0.249 0.000
N04.2 Diffuse membranous glomerulonephritis
0.750 0.250 0.000
E14.1 With ketoacidosis
0.750 0.250 0.000
L43.0 Hypertrophic lichen planus
0.748 0.252 0.000
E10.0 With coma
0.742 0.258 0.000
C91.9 Lymphoid leukaemia, unspecified
0.741 0.259 0.000
C81.0 Lymphocytic predominance
0.740 0.259 0.000
E31 Polyglandular dysfunction
0.740 0.260 0.000
E14.5 With peripheral circulatory complications
0.735 0.265 0.000
E27.9 Disorder of adrenal gland, unspecified
0.735 0.265 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.731 0.269 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.729 0.271 0.000
E20 Hypoparathyroidism
0.728 0.272 0.000
E21.2 Other hyperparathyroidism
0.725 0.275 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.725 0.275 0.000
E23.7 Disorder of pituitary gland, unspecified
0.720 0.280 0.000
Chapter VII Diseases of the eye and adnexa
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C83.6 Undifferentiated (diffuse)
0.717 0.283 0.000
C83.5 Lymphoblastic (diffuse)
0.717 0.283 0.000
C83.4 Immunoblastic (diffuse)
0.717 0.283 0.000
C83.2 Mixed small and large cell (diffuse)
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
C85.0 Lymphosarcoma
0.717 0.283 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.284 0.716
E28.3 Primary ovarian failure
0.715 0.285 0.000
C95 Leukaemia of unspecified cell type
0.715 0.285 0.000
N05.1 Focal and segmental glomerular lesions
0.713 0.287 0.000
E24 Cushing's syndrome
0.713 0.287 0.000
N03.1 Focal and segmental glomerular lesions
0.711 0.289 0.000
Q43 Other congenital malformations of intestine
0.710 0.290 0.000
L40.1 Generalised pustular psoriasis
0.710 0.290 0.000
E21.4 Other specified disorders of parathyroid gland
0.709 0.291 0.000
C82.6 Cutaneous follicle centre lymphoma
0.708 0.292 0.000
C82.5 Diffuse follicle centre lymphoma
0.708 0.292 0.000
C82.4 Follicular lymphoma grade IIIb
0.708 0.292 0.000
C84.4 Peripheral T-cell lymphoma
0.708 0.292 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.293 0.707
L10-L14 Bullous disorders
0.707 0.293 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.705 0.295 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.296 0.704
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.297 0.703
E14.3 With ophthalmic complications
0.702 0.298 0.000
C86 Other specified types of T/NK-cell lymphoma
0.700 0.300 0.000
C81.2 Mixed cellularity
0.698 0.302 0.000
N18.0 End-stage renal disease
0.696 0.304 0.000
E11.7 With multiple complications
0.694 0.305 0.000
E34.8 Other specified endocrine disorders
0.694 0.305 0.000
N18.3 Chronic kidney disease, stage 3
0.694 0.306 0.000
L43.8 Other lichen planus
0.694 0.306 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.687 0.313 0.000
L40.2 Acrodermatitis continua
0.686 0.314 0.000
Q00-Q07 Congenital malformations of the nervous system
0.686 0.314 0.000
E27.5 Adrenomedullary hyperfunction
0.685 0.314 0.000
E27.0 Other adrenocortical overactivity
0.685 0.314 0.000
L44 Other papulosquamous disorders
0.685 0.314 0.000
L41 Parapsoriasis
0.685 0.314 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.685 0.314 0.000
L43.3 Subacute (active) lichen planus
0.685 0.315 0.000
L43.2 Lichenoid drug reaction
0.685 0.315 0.000
L43.1 Bullous lichen planus
0.685 0.315 0.000
E13 Other specified diabetes mellitus
0.684 0.316 0.000
E11.6 With other specified complications
0.682 0.318 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.681 0.319 0.000
Q61.0 Congenital single renal cyst
0.677 0.323 0.000
M06.2 Rheumatoid bursitis
0.000 0.324 0.676
M06.1 Adult-onset Still's disease
0.000 0.324 0.676
L40.4 Guttate psoriasis
0.674 0.326 0.000
E28.9 Ovarian dysfunction, unspecified
0.674 0.326 0.000
E28.8 Other ovarian dysfunction
0.674 0.326 0.000
E28.1 Androgen excess
0.674 0.326 0.000
E28.0 Oestrogen excess
0.674 0.326 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.329 0.671
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.668 0.331 0.000
D60-D64 Aplastic and other anaemias
0.667 0.333 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.667 0.333 0.000
C88 Malignant immunoproliferative diseases
0.665 0.335 0.000
E11.8 With unspecified complications
0.665 0.335 0.000
C82.3 Follicular lymphoma grade IIIa
0.664 0.336 0.000
Q61.2 Polycystic kidney, adult type
0.661 0.339 0.000
Q50-Q56 Congenital malformations of genital organs
0.660 0.340 0.000
E25 Adrenogenital disorders
0.660 0.340 0.000
L13 Other bullous disorders
0.660 0.340 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.659 0.341 0.000
C81.3 Lymphocytic depletion
0.659 0.341 0.000
E23.6 Other disorders of pituitary gland
0.659 0.341 0.000
D61 Other aplastic anaemias
0.659 0.341 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.658 0.342 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.658 0.342 0.000
E22 Hyperfunction of pituitary gland
0.658 0.342 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.657 0.343 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.657 0.343 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.657 0.343 0.000
C84.3 Lymphoepithelioid lymphoma
0.657 0.343 0.000
C84.2 T-zone lymphoma
0.657 0.343 0.000
C84.1 Sezary's diease
0.657 0.343 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.656 0.344 0.000
N06 Isolated proteinuria with specified morphological lesion
0.656 0.344 0.000
N01 Rapidly progressive nephritic syndrome
0.656 0.344 0.000
C91.5 Adult T-cell leukaemia
0.656 0.344 0.000
E15 Nondiabetic hypoglycaemic coma
0.655 0.345 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.346 0.653
M06.38 Rheumatoid nodule (Other)
0.000 0.346 0.653
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.346 0.653
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.346 0.653
M06.33 Rheumatoid nodule (Forearm)
0.000 0.346 0.653
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.346 0.653
E27.2 Addisonian crisis
0.653 0.346 0.000
C84.0 Mycosis fungoides
0.653 0.347 0.000
N04.8 Other
0.653 0.347 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.653 0.347 0.000
N04.6 Dense deposit disease
0.653 0.347 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.653 0.347 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.653 0.347 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.653 0.347 0.000
D61.9 Aplastic anaemia, unspecified
0.651 0.349 0.000
H30 Chorioretinal inflammation
0.651 0.349 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.648 0.352 0.000
H34.2 Other retinal artery occlusions
0.647 0.353 0.000
E34.9 Endocrine disorder, unspecified
0.647 0.353 0.000
N05.8 Other
0.647 0.353 0.000
E14.7 With multiple complications
0.647 0.353 0.000
E14.0 With coma
0.647 0.353 0.000
L42 Pityriasis rosea
0.645 0.355 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.644 0.355 0.000
N03.6 Dense deposit disease
0.644 0.355 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.644 0.355 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.644 0.355 0.000
N03.2 Diffuse membranous glomerulonephritis
0.644 0.355 0.000
N03.0 Minor glomerular abnormality
0.644 0.355 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.644 0.356 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.642 0.358 0.000
N04.0 Minor glomerular abnormality
0.641 0.359 0.000
Q60.2 Renal agenesis, unspecified
0.640 0.360 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.638 0.362 0.000
E10.6 With other specified complications
0.633 0.367 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.369 0.631
E14.2 Withrenal complications
0.631 0.369 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.371 0.629
M05-M14 Inflammatory polyarthropathies
0.001 0.372 0.627
L13.0 Dermatitis herpetiformis
0.626 0.374 0.000
E07.1 Dyshormogenetic goitre
0.624 0.376 0.000
E07.0 Hypersecretion of calcitonin
0.624 0.376 0.000
N00 Acute nephritic syndrome
0.624 0.376 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.376 0.624
E06.5 Other chronic thyroiditis
0.622 0.378 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.621 0.378 0.000
N02 Recurrent and persistent haematuria
0.621 0.378 0.000
Q61.9 Cystic kidney disease, unspecified
0.618 0.382 0.000
E26.9 Hyperaldosteronism, unspecified
0.617 0.383 0.000
N05.6 Dense deposit disease
0.616 0.384 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.616 0.384 0.000
N05.0 Minor glomerular abnormality
0.616 0.384 0.000
N18.8 Other chronic renal failure
0.616 0.384 0.000
Q80-Q89 Other congenital malformations
0.615 0.385 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.613 0.387 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.613 0.387 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.613 0.387 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.613 0.387 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.611 0.389 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.611 0.389 0.000
E16.4 Abnormal secretion of gastrin
0.611 0.389 0.000
E16.3 Increased secretion of glucagon
0.611 0.389 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.609 0.391 0.000
E03.5 Myxoedema coma
0.605 0.395 0.000
E03.4 Atrophy of thyroid (acquired)
0.605 0.395 0.000
E03.3 Postinfectious hypothyroidism
0.605 0.395 0.000
E03.1 Congenital hypothyroidism without goitre
0.605 0.395 0.000
E06.4 Drug-induced thyroiditis
0.604 0.396 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.604 0.396 0.000
E06.1 Subacute thyroiditis
0.604 0.396 0.000
E06.0 Acute thyroiditis
0.604 0.396 0.000
Q60.0 Renal agenesis, unilateral
0.602 0.398 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.602 0.398 0.000
E05.8 Other thyrotoxicosis
0.600 0.400 0.000
Chapter II Neoplasms
0.600 0.400 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.599 0.401 0.000
D55-D59 Haemolytic anaemias
0.597 0.403 0.000
L20-L30 Dermatitis and eczema
0.596 0.404 0.000
C81.7 Other Hodgkin's disease
0.591 0.408 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.590 0.410 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.589 0.411 0.000
E46 Unspecified protein-energy malnutrition
0.588 0.412 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.586 0.414 0.000
E23.1 Drug-induced hypopituitarism
0.586 0.414 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.414 0.586
H36.8 Other retinal disorders in diseases classified elsewhere
0.585 0.414 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.585 0.415 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.583 0.417 0.000
E26.0 Primary hyperaldosteronism
0.582 0.418 0.000
Q61.4 Renal dysplasia
0.581 0.419 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.420 0.580
C95.0 Acute leukaemia of unspecified cell type
0.579 0.421 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.579 0.421 0.000
N02.2 Diffuse membranous glomerulonephritis
0.577 0.423 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.424 0.576
C93 Monocytic leukaemia
0.576 0.424 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.576 0.424 0.000
E34.5 Androgen resistance syndrome
0.575 0.425 0.000
E34.4 Constitutional tall stature
0.575 0.425 0.000
E34.3 Short stature, not elsewhere classified
0.575 0.425 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.575 0.425 0.000
E34.1 Other hypersecretion of intestinal hormones
0.575 0.425 0.000
L50-L54 Urticaria and erythema
0.574 0.426 0.000
Q07 Other congenital malformations of nervous system
0.573 0.427 0.000
E29 Testicular dysfunction
0.573 0.427 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.429 0.571
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.429 0.571
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.429 0.571
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.429 0.571
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.429 0.571
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.429 0.571
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.429 0.571
Q61.8 Other cystic kidney diseases
0.569 0.431 0.000
Q61.1 Polycystic kidney, infantile type
0.569 0.431 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.569 0.431 0.000
E14.6 With other specified complications
0.567 0.433 0.000
E24.2 Drug-induced Cushing's syndrome
0.566 0.434 0.000
E03.9 Hypothyroidism, unspecified
0.565 0.435 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.564 0.436 0.000
C91.7 Other lymphoid leukaemia
0.564 0.436 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.564 0.436 0.000
C91.3 Prolymphocytic leukaemia
0.564 0.436 0.000
C91.2 Subacute lymphocytic leukaemia
0.564 0.436 0.000
H34.0 Transient retinal artery occlusion
0.564 0.436 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.564 0.436 0.000
E26.8 Other hyperaldosteronism
0.563 0.437 0.000
E26.1 Secondary hyperaldosteronism
0.563 0.437 0.000
D80-D89 Certain disorders involving the immune mechanism
0.560 0.440 0.000
D64 Other anaemias
0.560 0.440 0.000
Q03 Congenital hydrocephalus
0.559 0.441 0.000
Q43.1 Hirschsprung's disease
0.557 0.443 0.000
N18.1 Chronic kidney disease, stage 1
0.555 0.445 0.000
Q64 Other congenital malformations of urinary system
0.554 0.445 0.000
E31.0 Autoimmune polyglandular failure
0.554 0.446 0.000
Q55 Other congenital malformations of male genital organs
0.551 0.449 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.450 0.550
H30.9 Chorioretinal inflammation, unspecified
0.549 0.451 0.000
E03.8 Other specified hypothyroidism
0.547 0.453 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.545 0.455 0.000
E45 Retarded development following protein-energy malnutrition
0.545 0.455 0.000
E43 Unspecified severe protein-energy malnutrition
0.545 0.455 0.000
E42 Marasmic kwashiorkor
0.545 0.455 0.000
E41 Nutritional marasmus
0.545 0.455 0.000
E40 Kwashiorkor
0.545 0.455 0.000
C83.0 Small cell (diffuse)
0.545 0.455 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.544 0.456 0.000
Q51 Congenital malformations of uterus and cervix
0.544 0.456 0.000
H34.1 Central retinal artery occlusion
0.541 0.459 0.000
N05.9 Unspecified
0.541 0.459 0.000
E24.0 Pituitary-dependent Cushing's disease
0.539 0.461 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.461 0.539
J45 Asthma
0.000 0.461 0.539
Q42 Congenital absence, atresia and stenosis of large intestine
0.539 0.461 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.539 0.461 0.000
Q35-Q37 Cleft lip and cleft palate
0.538 0.462 0.000
Q43.0 Meckel's diverticulum
0.537 0.463 0.000
Q44.6 Cystic disease of liver
0.535 0.464 0.000
Q04 Other congenital malformations of brain
0.534 0.465 0.000
E20.9 Hypoparathyroidism, unspecified
0.533 0.467 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.532 0.468 0.000
Q63 Other congenital malformations of kidney
0.532 0.468 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.531 0.469 0.000
E31.9 Polyglandular dysfunction, unspecified
0.531 0.469 0.000
E31.8 Other polyglandular dysfunction
0.531 0.469 0.000
E31.1 Polyglandular hyperfunction
0.531 0.469 0.000
L28 Lichen simplex chronicus and prurigo
0.530 0.470 0.000
C91.0 Acute lymphoblastic leukaemia
0.526 0.474 0.000
L10 Pemphigus
0.526 0.474 0.000
C90.3 Solitary plasmacytoma
0.525 0.475 0.000
Q85 Phakomatoses, not elsewhere classified
0.524 0.475 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.523 0.477 0.000
D61.0 Constitutional aplastic anaemia
0.522 0.478 0.000
E20.8 Other hypoparathyroidism
0.522 0.478 0.000
E20.1 Pseudohypoparathyroidism
0.522 0.478 0.000
E20.0 Idiopathic hypoparathyroidism
0.522 0.478 0.000
Q44.5 Other congenital malformations of bile ducts
0.520 0.479 0.000
Q60.6 Potter's syndrome
0.520 0.480 0.000
Q60.5 Renal hypoplasia, unspecified
0.520 0.480 0.000
Q60.4 Renal hypoplasia, bilateral
0.520 0.480 0.000
Q60.3 Renal hypoplasia, unilateral
0.520 0.480 0.000
Q60.1 Renal agenesis, bilateral
0.520 0.480 0.000
Q44.7 Other congenital malformations of liver
0.520 0.480 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.517 0.483 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.515 0.485 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
C94.7 Other specified leukaemias
0.514 0.486 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.514 0.486 0.000
C94.5 Acute myelofibrosis
0.514 0.486 0.000
C94.4 Acute panmyelosis
0.514 0.486 0.000
C94.3 Mast cell leukaemia
0.514 0.486 0.000
C94.2 Acute megakaryoblastic leukaemia
0.514 0.486 0.000
C94.1 Chronic erythraemia
0.514 0.486 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.514 0.486 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.514 0.486 0.000
C96.8 Histiocytic sarcoma
0.514 0.486 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.514 0.486 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.514 0.486 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.514 0.486 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.514 0.486 0.000
C96.3 True histiocytic lymphoma
0.514 0.486 0.000
C96.2 Malignant mast cell tumour
0.514 0.486 0.000
C96.1 Malignant histiocytosis
0.514 0.486 0.000
C96.0 Letterer-Siwe disease
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.514 0.486 0.000
E30.8 Other disorders of puberty
0.514 0.486 0.000
E30.1 Precocious puberty
0.514 0.486 0.000
E30.0 Delayed puberty
0.514 0.486 0.000
E32.9 Disease of thymus, unspecified
0.514 0.486 0.000
E32.8 Other diseases of thymus
0.514 0.486 0.000
E32.1 Abscess of thymus
0.514 0.486 0.000
E32.0 Persistent hyperplasia of thymus
0.514 0.486 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.514 0.486 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.514 0.486 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.514 0.486 0.000
Q43.3 Congenital malformations of intestinal fixation
0.514 0.486 0.000
E23.2 Diabetes insipidus
0.514 0.486 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.514 0.486 0.000
E16.1 Other hypoglycaemia
0.513 0.487 0.000
Q40 Other congenital malformations of upper alimentary tract
0.513 0.487 0.000
C95.7 Other leukaemia of unspecified cell type
0.512 0.487 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.512 0.487 0.000
L40.8 Other psoriasis
0.512 0.488 0.000
N17 Acute renal failure
0.512 0.488 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.488 0.511
E24.8 Other Cushing's syndrome
0.511 0.488 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.511 0.488 0.000
E24.3 Ectopic ACTH syndrome
0.511 0.488 0.000
E24.1 Nelson's syndrome
0.511 0.488 0.000
K90 Intestinal malabsorption
0.511 0.489 0.000
E07.9 Disorder of thyroid, unspecified
0.510 0.489 0.000
Q43.7 Persistent cloaca
0.509 0.491 0.000
Q43.6 Congenital fistula of rectum and anus
0.509 0.491 0.000
Q43.5 Ectopic anus
0.509 0.491 0.000
Q43.4 Duplication of intestine
0.509 0.491 0.000
Q43.2 Other congenital functional disorders of colon
0.509 0.491 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.491 0.509
N25-N29 Other disorders of kidney and ureter
0.508 0.492 0.000
L14 Bullous disorders in diseases classified elsewhere
0.507 0.493 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.507 0.493 0.000
L52 Erythema nodosum
0.507 0.493 0.000
Q39 Congenital malformations of oesophagus
0.506 0.494 0.000
E13.9 Without complications
0.505 0.495 0.000
Q61.5 Medullary cystic kidney
0.504 0.496 0.000
M12 Other specific arthropathies
0.001 0.497 0.503
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.502 0.498 0.000
C86.4 Blastic NK-cell lymphoma
0.502 0.498 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.502 0.498 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.502 0.498 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.502 0.498 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.502 0.498 0.000
C02.9 Tongue, unspecified
0.500 0.500 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.501 0.499
Q43.8 Other specified congenital malformations of intestine
0.498 0.502 0.000
D59 Acquired haemolytic anaemia
0.496 0.504 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.495 0.505 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.495 0.505 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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