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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3117761
log Bayes Factor = 17.5062
Chromosome 1   position 177,722,715  (GRCh37) Explore rs3117761 on Ensembl!
Variant rs3117761 is part of Cluster X0044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.994 0.006 0.000
Chapter IX Diseases of the circulatory system
0.989 0.011 0.000
R05 Cough
0.988 0.012 0.000
J47 Bronchiectasis
0.981 0.019 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.980 0.020 0.000
M05-M14 Inflammatory polyarthropathies
0.979 0.021 0.000
J44 Other chronic obstructive pulmonary disease
0.975 0.025 0.000
S60-S69 Injuries to the wrist and hand
0.972 0.028 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.968 0.032 0.000
L60-L75 Disorders of skin appendages
0.968 0.032 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.965 0.035 0.000
I30-I52 Other forms of heart disease
0.962 0.038 0.000
Chapter II Neoplasms
0.959 0.041 0.000
M06 Other rheumatoid arthritis
0.952 0.048 0.000
Chapter I Certain infectious and parasitic diseases
0.950 0.050 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.947 0.053 0.000
J90-J94 Other diseases of pleura
0.945 0.055 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.941 0.059 0.000
Chapter VI Diseases of the nervous system
0.939 0.061 0.000
J95-J99 Other diseases of the respiratory system
0.937 0.063 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.929 0.071 0.000
S50-S59 Injuries to the elbow and forearm
0.929 0.071 0.000
R04 Haemorrhage from respiratory passages
0.928 0.072 0.000
M06.9 Rheumatoid arthritis, unspecified
0.927 0.073 0.000
J09-J18 Influenza and pneumonia
0.926 0.074 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.920 0.080 0.000
J90 Pleural effusion, not elsewhere classified
0.919 0.081 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.917 0.083 0.000
S20-S29 Injuries to the thorax
0.915 0.085 0.000
R00 Abnormalities of heart beat
0.913 0.087 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.909 0.091 0.000
M50-M54 Other dorsopathies
0.907 0.093 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.907 0.093 0.000
J60-J70 Lung diseases due to external agents
0.907 0.093 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.903 0.097 0.000
Y95 Nosocomial condition
0.901 0.099 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.900 0.100 0.000
R50-R69 General symptoms and signs
0.894 0.106 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.894 0.106 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.892 0.108 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.892 0.108 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.889 0.111 0.000
J43 Emphysema
0.888 0.112 0.000
B95-B98 Bacterial, viral and other infectious agents
0.887 0.113 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.879 0.121 0.000
I34 Nonrheumatic mitral valve disorders
0.879 0.121 0.000
R00.0 Tachycardia, unspecified
0.878 0.122 0.000
J98 Other respiratory disorders
0.878 0.122 0.000
I60-I69 Cerebrovascular diseases
0.878 0.122 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.876 0.124 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.874 0.126 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.873 0.127 0.000
M10 Gout
0.873 0.127 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.873 0.127 0.000
G90-G99 Other disorders of the nervous system
0.871 0.129 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.871 0.129 0.000
M80-M85 Disorders of bone density and structure
0.870 0.130 0.000
L72.0 Epidermal cyst
0.870 0.130 0.000
S52 Fracture of forearm
0.869 0.131 0.000
R04.2 Haemoptysis
0.868 0.132 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.866 0.134 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.863 0.137 0.000
M15-M19 Arthrosis
0.862 0.138 0.000
J18 Pneumonia, organism unspecified
0.860 0.140 0.000
I45 Other conduction disorders
0.859 0.141 0.000
R63 Symptoms and signs concerning food and fluid intake
0.859 0.141 0.000
R47-R49 Symptoms and signs involving speech and voice
0.857 0.143 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.855 0.145 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.855 0.145 0.000
T66-T78 Other and unspecified effects of external causes
0.852 0.148 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.851 0.149 0.000
Chapter VIII Diseases of the ear and mastoid process
0.850 0.150 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.850 0.150 0.000
R01 Cardiac murmurs and other cardiac sounds
0.849 0.151 0.000
I27 Other pulmonary heart diseases
0.848 0.152 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.848 0.152 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.847 0.153 0.000
M19 Other arthrosis
0.847 0.153 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.841 0.159 0.000
J69 Pneumonitis due to solids and liquids
0.839 0.161 0.000
I49 Other cardiac arrhythmias
0.836 0.164 0.000
R06 Abnormalities of breathing
0.834 0.166 0.000
M19.9 Arthrosis, unspecified
0.833 0.167 0.000
S52.5 Fracture of lower end of radius
0.832 0.167 0.000
R26 Abnormalities of gait and mobility
0.832 0.168 0.000
R14 Flatulence and related conditions
0.831 0.169 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.831 0.169 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.827 0.173 0.000
R63.4 Abnormal weight loss
0.826 0.174 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.825 0.175 0.000
R15 Faecal incontinence
0.825 0.175 0.000
T39.1 4-Aminophenol derivatives
0.821 0.179 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.811 0.189 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.811 0.189 0.000
J43.9 Emphysema, unspecified
0.809 0.191 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.808 0.192 0.000
S62 Fracture at wrist and hand level
0.807 0.192 0.000
R06.0 Dyspnoea
0.807 0.193 0.000
S52.50 Fracture of lower end of radius (closed)
0.806 0.194 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.806 0.194 0.000
L81 Other disorders of pigmentation
0.805 0.195 0.000
I34.0 Mitral (valve) insufficiency
0.804 0.196 0.000
I50 Heart failure
0.803 0.197 0.000
R11 Nausea and vomiting
0.801 0.199 0.000
I05-I09 Chronic rheumatic heart diseases
0.799 0.201 0.000
I51 Complications and ill-defined descriptions of heart disease
0.798 0.201 0.000
B35-B49 Mycoses
0.798 0.202 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.798 0.202 0.000
S61 Open wound of wrist and hand
0.797 0.203 0.000
M10.9 Gout, unspecified
0.797 0.203 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.795 0.205 0.000
M11 Other crystal arthropathies
0.793 0.207 0.000
Chapter XXII Codes for special purposes
0.793 0.207 0.000
R18 Ascites
0.792 0.208 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.791 0.209 0.000
J69.0 Pneumonitis due to food and vomit
0.790 0.210 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.790 0.210 0.000
S27 Injury of other and unspecified intrathoracic organs
0.789 0.211 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.788 0.211 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.781 0.219 0.000
J18.9 Pneumonia, unspecified
0.779 0.221 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.779 0.221 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.778 0.222 0.000
D00-D09 In situ neoplasms
0.777 0.223 0.000
G95 Other diseases of spinal cord
0.777 0.223 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.776 0.224 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.775 0.225 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.772 0.227 0.000
R50 Fever of unknown origin
0.772 0.228 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.771 0.229 0.000
L82 Seborrhoeic keratosis
0.771 0.229 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.770 0.230 0.000
L89 Decubitus ulcer
0.770 0.230 0.000
I63 Cerebral infarction
0.770 0.230 0.000
I69 Sequelae of cerebrovascular disease
0.769 0.231 0.000
M50 Cervical disk disorders
0.769 0.231 0.000
V20-V29 Motorcycle rider injured in transport accident
0.767 0.233 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.765 0.235 0.000
M45-M49 Spondylopathies
0.765 0.235 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.764 0.235 0.000
R87 Abnormal findings in specimens from female genital organs
0.764 0.236 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.763 0.237 0.000
J84 Other interstitial pulmonary diseases
0.763 0.237 0.000
R53 Malaise and fatigue
0.762 0.238 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.761 0.239 0.000
T39.0 Salicylates
0.761 0.239 0.000
R09.0 Asphyxia
0.761 0.239 0.000
A30-A49 Other bacterial diseases
0.760 0.240 0.000
T81 Complications of procedures, not elsewhere classified
0.759 0.241 0.000
D45 Polycythaemia vera
0.758 0.242 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.757 0.243 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.757 0.243 0.000
W00-W19 Falls
0.757 0.243 0.000
J98.1 Pulmonary collapse
0.756 0.244 0.000
M51 Other intervertebral disk disorders
0.755 0.245 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.754 0.246 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.751 0.249 0.000
M86-M90 Other osteopathies
0.750 0.250 0.000
L72.1 Trichilemmal cyst
0.750 0.250 0.000
I73 Other peripheral vascular diseases
0.748 0.252 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.746 0.254 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.746 0.254 0.000
R54 Senility
0.746 0.254 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.745 0.254 0.000
T78 Adverse effects, not elsewhere classified
0.745 0.255 0.000
S40-S49 Injuries to the shoulder and upper arm
0.745 0.255 0.000
V10-V19 Pedal cyclist injured in transport accident
0.745 0.255 0.000
M91-M94 Chondropathies
0.745 0.255 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.744 0.256 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.744 0.256 0.000
T51 Toxic effect of alcohol
0.743 0.257 0.000
C60-C63 Malignant neoplasms of male genital organs
0.742 0.258 0.000
L40-L45 Papulosquamous disorders
0.742 0.258 0.000
R01.1 Cardiac murmur, unspecified
0.742 0.258 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.741 0.258 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.741 0.259 0.000
R00.1 Bradycardia, unspecified
0.741 0.259 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.740 0.260 0.000
R09.3 Abnormal sputum
0.740 0.260 0.000
G93 Other disorders of brain
0.740 0.260 0.000
S69 Other and unspecified injuries of wrist and hand
0.738 0.262 0.000
C78.7 Secondary malignant neoplasm of liver
0.736 0.264 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.736 0.264 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.736 0.264 0.000
I45.1 Other and unspecified right bundle-branch block
0.735 0.265 0.000
J14 Pneumonia due to Haemophilus influenzae
0.734 0.266 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.733 0.267 0.000
Y85 Sequelae of transport accidents
0.733 0.267 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.733 0.267 0.000
M06.0 Seronegative rheumatoid arthritis
0.732 0.268 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.732 0.268 0.000
C34 Malignant neoplasm of bronchus and lung
0.732 0.268 0.000
H65-H75 Diseases of middle ear and mastoid
0.731 0.269 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.731 0.269 0.000
I27.0 Primary pulmonary hypertension
0.730 0.270 0.000
M81 Osteoporosis without pathological fracture
0.728 0.272 0.000
R59 Enlarged lymph nodes
0.728 0.272 0.000
S20 Superficial injury of thorax
0.728 0.272 0.000
R68 Other general symptoms and signs
0.727 0.272 0.000
I26 Pulmonary embolism
0.727 0.273 0.000
Y86 Sequelae of other accidents
0.727 0.273 0.000
Chapter V Mental and behavioural disorders
0.726 0.274 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.725 0.275 0.000
W20-W49 Exposure to inanimate mechanical forces
0.724 0.276 0.000
J18.1 Lobar pneumonia, unspecified
0.724 0.276 0.000
R09.2 Respiratory arrest
0.723 0.277 0.000
R49 Voice disturbances
0.723 0.277 0.000
R57 Shock, not elsewhere classified
0.722 0.277 0.000
Y84.8 Other medical procedures
0.722 0.278 0.000
T43.2 Other and unspecified antidepressants
0.722 0.278 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.721 0.279 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.719 0.281 0.000
T90 Sequelae of injuries of head
0.719 0.281 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.719 0.281 0.000
I27.2 Other secondary pulmonary hypertension
0.719 0.281 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J46 Status asthmaticus
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.715 0.284 0.000
J42 Unspecified chronic bronchitis
0.715 0.284 0.000
L60 Nail disorders
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
S68 Traumatic amputation of wrist and hand
0.713 0.287 0.000
M60-M63 Disorders of muscles
0.713 0.287 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
L20-L30 Dermatitis and eczema
0.713 0.287 0.000
L10-L14 Bullous disorders
0.712 0.287 0.000
L84 Corns and callosities
0.711 0.289 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.711 0.289 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.709 0.291 0.000
S90-S99 Injuries to the ankle and foot
0.709 0.291 0.000
X60-X84 Intentional self-harm
0.709 0.291 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.708 0.291 0.000
S61.8 Open wound of other parts of wrist and hand
0.708 0.292 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.707 0.293 0.000
I49.5 Sick sinus syndrome
0.707 0.293 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.707 0.293 0.000
T93 Sequelae of injuries of lower limb
0.707 0.293 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.705 0.295 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.705 0.295 0.000
I73.9 Peripheral vascular disease, unspecified
0.705 0.295 0.000
L98.0 Pyogenic granuloma
0.705 0.295 0.000
S50 Superficial injury of forearm
0.704 0.296 0.000
R04.0 Epistaxis
0.703 0.297 0.000
J98.8 Other specified respiratory disorders
0.703 0.297 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.703 0.297 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.703 0.297 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.703 0.297 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.703 0.297 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.703 0.297 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.703 0.297 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.703 0.297 0.000
T36 Poisoning by systemic antibiotics
0.703 0.297 0.000
G70-G73 Diseases of myoneural junction and muscle
0.702 0.297 0.000
M14 Arthropathies in other diseases classified elsewhere
0.702 0.298 0.000
M12 Other specific arthropathies
0.702 0.298 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.702 0.298 0.000
M08 Juvenile arthritis
0.702 0.298 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.701 0.299 0.000
L85 Other epidermal thickening
0.700 0.300 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.699 0.301 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.699 0.301 0.000
M54 Dorsalgia
0.699 0.301 0.000
C51-C58 Malignant neoplasms of female genital organs
0.699 0.301 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.698 0.302 0.000
S67 Crushing injury of wrist and hand
0.697 0.303 0.000
S65 Injury of blood vessels at wrist and hand level
0.697 0.303 0.000
S60 Superficial injury of wrist and hand
0.697 0.303 0.000
S64 Injury of nerves at wrist and hand level
0.695 0.305 0.000
T87 Complications peculiar to reattachment and amputation
0.694 0.306 0.000
T86 Failure and rejection of transplanted organs and tissues
0.694 0.306 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.694 0.306 0.000
L75 Apocrine sweat disorders
0.694 0.306 0.000
L74 Eccrine sweat disorders
0.694 0.306 0.000
L73 Other follicular disorders
0.694 0.306 0.000
L71 Rosacea
0.694 0.306 0.000
L70 Acne
0.694 0.306 0.000
L68 Hypertrichosis
0.694 0.306 0.000
L67 Hair colour and hair shaft abnormalities
0.694 0.306 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.694 0.306 0.000
L65 Other nonscarring hair loss
0.694 0.306 0.000
L64 Androgenic alopecia
0.694 0.306 0.000
L63 Alopecia areata
0.694 0.306 0.000
L62 Nail disorders in diseases classified elsewhere
0.694 0.306 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.693 0.307 0.000
G30-G32 Other degenerative diseases of the nervous system
0.692 0.307 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.692 0.308 0.000
L94 Other localised connective tissue disorders
0.692 0.308 0.000
L93 Lupus erythematosus
0.692 0.308 0.000
L87 Transepidermal elimination disorders
0.692 0.308 0.000
L88 Pyoderma gangrenosum
0.692 0.308 0.000
L86 Keratoderma in diseases classified elsewhere
0.692 0.308 0.000
L83 Acanthosis nigricans
0.692 0.308 0.000
L80 Vitiligo
0.692 0.308 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.692 0.308 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.690 0.310 0.000
I52 Other heart disorders in diseases classified elsewhere
0.690 0.310 0.000
I48 Atrial fibrillation and flutter
0.690 0.310 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.690 0.310 0.000
I41 Myocarditis in diseases classified elsewhere
0.690 0.310 0.000
I40 Acute myocarditis
0.690 0.310 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.690 0.310 0.000
I37 Pulmonary valve disorders
0.690 0.310 0.000
I36 Nonrheumatic tricuspid valve disorders
0.690 0.310 0.000
I33 Acute and subacute endocarditis
0.690 0.310 0.000
I32 Pericarditis in diseases classified elsewhere
0.690 0.310 0.000
I30 Acute pericarditis
0.690 0.310 0.000
I38 Endocarditis, valve unspecified
0.690 0.310 0.000
S70-S79 Injuries to the hip and thigh
0.689 0.311 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.689 0.311 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.688 0.312 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.688 0.312 0.000
M85 Other disorders of bone density and structure
0.688 0.312 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.688 0.312 0.000
D80-D89 Certain disorders involving the immune mechanism
0.687 0.312 0.000
I46 Cardiac arrest
0.687 0.313 0.000
R87.6 Abnormal cytological findings
0.686 0.314 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.686 0.314 0.000
Y40 Systemic antibiotics
0.685 0.314 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.685 0.315 0.000
I45.5 Other specified heart block
0.682 0.318 0.000
M06.8 Other specified rheumatoid arthritis
0.682 0.318 0.000
M06.4 Inflammatory polyarthropathy
0.682 0.318 0.000
M06.3 Rheumatoid nodule
0.682 0.318 0.000
M06.2 Rheumatoid bursitis
0.682 0.318 0.000
M06.1 Adult-onset Still's disease
0.682 0.318 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.682 0.318 0.000
I67 Other cerebrovascular diseases
0.682 0.318 0.000
I34.1 Mitral (valve) prolapse
0.682 0.318 0.000
I50.9 Heart failure, unspecified
0.681 0.319 0.000
B99-B99 Other infectious diseases
0.681 0.319 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.681 0.319 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.681 0.319 0.000
B65-B83 Helminthiases
0.681 0.319 0.000
B50-B64 Protozoal diseases
0.681 0.319 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.681 0.319 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.681 0.319 0.000
A80-A89 Viral infections of the central nervous system
0.681 0.319 0.000
A75-A79 Rickettsioses
0.681 0.319 0.000
A70-A74 Other diseases caused by chlamydiae
0.681 0.319 0.000
A65-A69 Other spirochaetal diseases
0.681 0.319 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.681 0.319 0.000
A20-A28 Certain zoonotic bacterial diseases
0.681 0.319 0.000
A15-A19 Tuberculosis
0.681 0.319 0.000
Y44 Agents primarily affecting blood constituents
0.679 0.321 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.679 0.321 0.000
L72.2 Steatocystoma multiplex
0.679 0.321 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.678 0.322 0.000
J94 Other pleural conditions
0.678 0.322 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.677 0.323 0.000
L81.4 Other melanin hyperpigmentation
0.677 0.323 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.677 0.323 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.676 0.324 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.675 0.325 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.675 0.325 0.000
Y98 Lifestyle-related condition
0.675 0.325 0.000
Y97 Environmental-pollution-related condition
0.675 0.325 0.000
Y96 Work-related condition
0.675 0.325 0.000
R45 Symptoms and signs involving emotional state
0.674 0.326 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.673 0.326 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.672 0.328 0.000
M05 Seropositive rheumatoid arthritis
0.672 0.328 0.000
J96 Respiratory failure, not elsewhere classified
0.671 0.328 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.671 0.328 0.000
I08 Multiple valve diseases
0.671 0.328 0.000
R47 Speech disturbances, not elsewhere classified
0.671 0.329 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.671 0.329 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.670 0.330 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.670 0.330 0.000
J98.4 Other disorders of lung
0.670 0.330 0.000
S62.6 Fracture of other finger
0.669 0.331 0.000
Y43 Primarily systemic agents
0.669 0.331 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.669 0.331 0.000
M65-M68 Disorders of synovium and tendon
0.669 0.331 0.000
I51.8 Other ill-defined heart diseases
0.668 0.332 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.668 0.332 0.000
B15-B19 Viral hepatitis
0.668 0.332 0.000
M07 Psoriatic and enteropathic arthropathies
0.667 0.333 0.000
S27.0 Traumatic pneumothorax
0.667 0.333 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.666 0.333 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.666 0.334 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.666 0.334 0.000
L98.5 Mucinosis of skin
0.666 0.334 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.666 0.334 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.666 0.334 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.666 0.334 0.000
L98.1 Factitial dermatitis
0.666 0.334 0.000
S59 Other and unspecified injuries of forearm
0.666 0.334 0.000
S58 Traumatic amputation of forearm
0.666 0.334 0.000
S57 Crushing injury of forearm
0.666 0.334 0.000
S56 Injury of muscle and tendon at forearm level
0.666 0.334 0.000
S55 Injury of blood vessels at forearm level
0.666 0.334 0.000
S54 Injury of nerves at forearm level
0.666 0.334 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.666 0.334 0.000
S51 Open wound of forearm
0.666 0.334 0.000
M53 Other dorsopathies, not elsewhere classified
0.666 0.334 0.000
I49.9 Cardiac arrhythmia, unspecified
0.666 0.334 0.000
D10-D36 Benign neoplasms
0.666 0.334 0.000
T82.1 Mechanical complication of cardiac electronic device
0.666 0.334 0.000
B37 Candidiasis
0.666 0.334 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.666 0.334 0.000
G95.1 Vascular myelopathies
0.666 0.334 0.000
D68 Other coagulation defects
0.665 0.334 0.000
S52.1 Fracture of upper end of radius
0.665 0.334 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.665 0.335 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.665 0.335 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.665 0.335 0.000
R04.1 Haemorrhage from throat
0.665 0.335 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.665 0.335 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.665 0.335 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.665 0.335 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.665 0.335 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.665 0.335 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.665 0.335 0.000
I49.8 Other specified cardiac arrhythmias
0.665 0.335 0.000
R63.1 Polydipsia
0.665 0.335 0.000
M10.90 Gout, unspecified (Multiple sites)
0.664 0.336 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.664 0.336 0.000
J17 Pneumonia in diseases classified elsewhere
0.664 0.336 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.664 0.336 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.664 0.336 0.000
J12 Viral pneumonia, not elsewhere classified
0.664 0.336 0.000
J11 Influenza, virus not identified
0.664 0.336 0.000
J10 Influenza due to identified influenza virus
0.664 0.336 0.000
J09 Influenza due to certain identified influenza virus
0.664 0.336 0.000
M70-M79 Other soft tissue disorders
0.663 0.337 0.000
I61 Intracerebral haemorrhage
0.662 0.338 0.000
L50-L54 Urticaria and erythema
0.661 0.339 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.661 0.339 0.000
R26.0 Ataxic gait
0.661 0.339 0.000
R63.0 Anorexia
0.661 0.339 0.000
M11.2 Other chondrocalcinosis
0.660 0.340 0.000
M84 Disorders of continuity of bone
0.660 0.340 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.659 0.341 0.000
I45.9 Conduction disorder, unspecified
0.659 0.341 0.000
I27.9 Pulmonary heart disease, unspecified
0.659 0.341 0.000
Y57 Other and unspecified drugs and medicaments
0.658 0.341 0.000
I28 Other diseases of pulmonary vessels
0.658 0.342 0.000
M19.0 Primary arthrosis of other joints
0.658 0.342 0.000
T92 Sequelae of injuries of upper limb
0.658 0.342 0.000
C79 Secondary malignant neoplasm of other sites
0.657 0.343 0.000
R42 Dizziness and giddiness
0.657 0.343 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.656 0.344 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.656 0.344 0.000
S29 Other and unspecified injuries of thorax
0.656 0.344 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.656 0.344 0.000
S26 Injury of heart
0.656 0.344 0.000
S25 Injury of blood vessels of thorax
0.656 0.344 0.000
S24 Injury of nerves and spinal cord at thorax level
0.656 0.344 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.656 0.344 0.000
S21 Open wound of thorax
0.656 0.344 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.654 0.346 0.000
R02 Gangrene, not elsewhere classified
0.653 0.346 0.000
H60-H62 Diseases of external ear
0.653 0.346 0.000
I50.1 Left ventricular failure
0.653 0.347 0.000
D60-D64 Aplastic and other anaemias
0.652 0.348 0.000
J93 Pneumothorax
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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