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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3128844
log Bayes Factor = 36.4038
Chromosome 6   position 29,459,260  (GRCh37) Explore rs3128844 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E10.9 Without complications
0.000 0.008 0.992
E10.3 With ophthalmic complications
0.000 0.019 0.981
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.024 0.976
E10.1 With ketoacidosis
0.000 0.036 0.964
E20-E35 Disorders of other endocrine glands
0.000 0.048 0.952
E10.4 With neurological complications
0.000 0.052 0.948
E50-E64 Other nutritional deficiencies
0.000 0.058 0.942
E10.2 With renal complications
0.000 0.060 0.940
E11 Non-insulin-dependent diabetes mellitus
0.000 0.067 0.933
E23 Hypofunction and other disorders of pituitary gland
0.000 0.067 0.933
E13 Other specified diabetes mellitus
0.000 0.070 0.930
E11.2 With renal complications
0.000 0.083 0.917
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.089 0.910
E23.0 Hypopituitarism
0.000 0.101 0.899
E10.5 With peripheral circulatory complications
0.000 0.109 0.891
E24 Cushing's syndrome
0.000 0.110 0.890
E10.6 With other specified complications
0.000 0.113 0.887
E61 Deficiency of other nutrient elements
0.000 0.125 0.875
E16 Other disorders of pancreatic internal secretion
0.000 0.137 0.863
E13.9 Without complications
0.000 0.137 0.863
E61.1 Iron deficiency
0.000 0.170 0.830
E24.0 Pituitary-dependent Cushing's disease
0.000 0.202 0.798
E23.2 Diabetes insipidus
0.000 0.203 0.797
E28 Ovarian dysfunction
0.000 0.205 0.795
E11.0 With coma
0.000 0.212 0.788
E16.1 Other hypoglycaemia
0.000 0.220 0.780
E11.5 With peripheral circulatory complications
0.000 0.220 0.780
E53 Deficiency of other B group vitamins
0.000 0.224 0.776
E10.0 With coma
0.000 0.225 0.775
E16.2 Hypoglycaemia, unspecified
0.000 0.230 0.770
E10.7 With multiple complications
0.000 0.231 0.769
E25 Adrenogenital disorders
0.000 0.237 0.763
E14 Unspecified diabetes mellitus
0.000 0.241 0.759
E55 Vitamin D deficiency
0.000 0.243 0.757
E00-E07 Disorders of thyroid gland
0.000 0.250 0.750
E13.3 With ophthalmic complications
0.000 0.264 0.736
E24.9 Cushing's syndrome, unspecified
0.000 0.264 0.736
E51 Thiamine deficiency
0.000 0.266 0.734
E10.8 With unspecified complications
0.000 0.267 0.733
E23.7 Disorder of pituitary gland, unspecified
0.000 0.269 0.731
E56 Other vitamin deficiencies
0.000 0.275 0.725
E11.1 With ketoacidosis
0.000 0.278 0.722
E24.2 Drug-induced Cushing's syndrome
0.000 0.278 0.722
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E20 Hypoparathyroidism
0.000 0.288 0.712
E07 Other disorders of thyroid
0.000 0.302 0.698
E28.3 Primary ovarian failure
0.000 0.311 0.689
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.317 0.683
E32 Diseases of thymus
0.000 0.317 0.683
E30 Disorders of puberty, not elsewhere classified
0.000 0.317 0.683
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.318 0.681
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.324 0.676
E63 Other nutritional deficiencies
0.000 0.324 0.676
E50 Vitamin A deficiency
0.000 0.324 0.676
E60 Dietary zinc deficiency
0.000 0.324 0.676
E59 Dietary selenium deficiency
0.000 0.324 0.676
E54 Ascorbic acid deficiency
0.000 0.324 0.676
E52 Niacin deficiency [pellagra]
0.000 0.324 0.676
E11.7 With multiple complications
0.000 0.331 0.669
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.331 0.669
E23.1 Drug-induced hypopituitarism
0.000 0.331 0.669
E11.6 With other specified complications
0.000 0.332 0.668
E13.8 With unspecified complications
0.000 0.333 0.666
E13.7 With multiple complications
0.000 0.333 0.666
E13.6 With other specified complications
0.000 0.333 0.666
E13.5 With peripheral circulatory complications
0.000 0.333 0.666
E13.4 With neurological complications
0.000 0.333 0.666
E13.2 With renal complications
0.000 0.333 0.666
E13.1 With ketoacidosis
0.000 0.333 0.666
E13.0 With coma
0.000 0.333 0.666
E14.5 With peripheral circulatory complications
0.000 0.338 0.662
E40-E46 Malnutrition
0.000 0.345 0.655
E15 Nondiabetic hypoglycaemic coma
0.000 0.347 0.653
E23.6 Other disorders of pituitary gland
0.000 0.349 0.651
E11.8 With unspecified complications
0.000 0.352 0.648
E53.8 Deficiency of other specified B group vitamins
0.000 0.356 0.644
E07.8 Other specified disorders of thyroid
0.000 0.360 0.640
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.362 0.638
E24.3 Ectopic ACTH syndrome
0.000 0.362 0.638
E24.1 Nelson's syndrome
0.000 0.362 0.638
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.369 0.631
E31 Polyglandular dysfunction
0.000 0.370 0.630
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.372 0.628
E61.9 Deficiency of nutrient element, unspecified
0.000 0.372 0.627
E61.8 Deficiency of other specified nutrient elements
0.000 0.372 0.627
E61.7 Deficiency of multiple nutrient elements
0.000 0.372 0.627
E61.6 Vanadium deficiency
0.000 0.372 0.627
E61.5 Molybdenum deficiency
0.000 0.372 0.627
E61.4 Chromium deficiency
0.000 0.372 0.627
E61.3 Manganese deficiency
0.000 0.372 0.627
E61.0 Copper deficiency
0.000 0.372 0.627
E29 Testicular dysfunction
0.000 0.375 0.625
E55.9 Vitamin D deficiency, unspecified
0.000 0.376 0.624
E14.4 With neurological complications
0.000 0.380 0.620
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.381 0.619
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.381 0.619
E16.4 Abnormal secretion of gastrin
0.000 0.381 0.619
E16.3 Increased secretion of glucagon
0.000 0.381 0.619
E61.2 Magnesium deficiency
0.000 0.389 0.611
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.395 0.605
E58 Dietary calcium deficiency
0.000 0.407 0.593
E05.9 Thyrotoxicosis, unspecified
0.000 0.408 0.592
E24.8 Other Cushing's syndrome
0.000 0.409 0.591
E14.1 With ketoacidosis
0.000 0.414 0.586
E34 Other endocrine disorders
0.000 0.415 0.585
E11.4 With neurological complications
0.000 0.415 0.585
E51.2 Wernicke's encephalopathy
0.000 0.415 0.585
E27 Other disorders of adrenal gland
0.000 0.415 0.585
E53.9 Vitamin B deficiency, unspecified
0.000 0.423 0.577
E14.6 With other specified complications
0.000 0.426 0.574
E07.9 Disorder of thyroid, unspecified
0.000 0.429 0.571
E28.9 Ovarian dysfunction, unspecified
0.000 0.430 0.570
E28.8 Other ovarian dysfunction
0.000 0.430 0.570
E28.1 Androgen excess
0.000 0.430 0.570
E28.0 Oestrogen excess
0.000 0.430 0.570
E56.1 Deficiency of vitamin K
0.000 0.431 0.569
E22 Hyperfunction of pituitary gland
0.000 0.440 0.560
E53.1 Pyridoxine deficiency
0.000 0.444 0.556
E53.0 Riboflavin deficiency
0.000 0.444 0.556
E28.2 Polycystic ovarian syndrome
0.000 0.445 0.555
E25.9 Adrenogenital disorder, unspecified
0.000 0.453 0.547
E25.8 Other adrenogenital disorders
0.000 0.453 0.547
E14.7 With multiple complications
0.000 0.455 0.544
E14.0 With coma
0.000 0.455 0.544
E55.0 Rickets, active
0.000 0.457 0.543
E27.1 Primary adrenocortical insufficiency
0.000 0.459 0.541
E20.9 Hypoparathyroidism, unspecified
0.000 0.461 0.539
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.462 0.538
E00 Congenital iodine-deficiency syndrome
0.000 0.462 0.538
E26 Hyperaldosteronism
0.000 0.463 0.537
E51.9 Thiamine deficiency, unspecified
0.000 0.474 0.526
E51.8 Other manifestations of thiamine deficiency
0.000 0.474 0.526
E51.1 Beriberi
0.000 0.474 0.526
E14.2 Withrenal complications
0.000 0.477 0.523
E56.9 Vitamin deficiency, unspecified
0.000 0.480 0.520
E56.8 Deficiency of other vitamins
0.000 0.480 0.520
E56.0 Deficiency of vitamin E
0.000 0.480 0.520
E14.8 With unspecified complications
0.000 0.483 0.517
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.487 0.513
E20.8 Other hypoparathyroidism
0.000 0.490 0.510
E20.1 Pseudohypoparathyroidism
0.000 0.490 0.510
E20.0 Idiopathic hypoparathyroidism
0.000 0.490 0.510
E07.1 Dyshormogenetic goitre
0.000 0.500 0.500
E07.0 Hypersecretion of calcitonin
0.000 0.500 0.500
E34.8 Other specified endocrine disorders
0.000 0.502 0.498
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.505 0.495
E30.9 Disorder of puberty, unspecified
0.000 0.510 0.490
E30.8 Other disorders of puberty
0.000 0.510 0.490
E30.1 Precocious puberty
0.000 0.510 0.490
E30.0 Delayed puberty
0.000 0.510 0.490
E32.9 Disease of thymus, unspecified
0.000 0.510 0.490
E32.8 Other diseases of thymus
0.000 0.510 0.490
E32.1 Abscess of thymus
0.000 0.510 0.490
E32.0 Persistent hyperplasia of thymus
0.000 0.510 0.490
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.510 0.490
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.510 0.490
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.510 0.490
E05.5 Thyroid crisis or storm
0.000 0.511 0.489
E05.4 Thyrotoxicosis factitia
0.000 0.511 0.489
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.511 0.489
E50.9 Vitamin A deficiency, unspecified
0.000 0.515 0.484
E50.8 Other manifestations of vitamin A deficiency
0.000 0.515 0.484
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.515 0.484
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.515 0.484
E50.5 Vitamin A deficiency with night blindness
0.000 0.515 0.484
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.515 0.484
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.515 0.484
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.515 0.484
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.515 0.484
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.515 0.484
E63.9 Nutritional deficiency, unspecified
0.000 0.515 0.484
E63.8 Other specified nutritional deficiencies
0.000 0.515 0.484
E63.1 Imbalance of constituents of food intake
0.000 0.515 0.484
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.515 0.484
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.515 0.484
E64.8 Sequelae of other nutritional deficiencies
0.000 0.515 0.484
E64.3 Sequelae of rickets
0.000 0.515 0.484
E64.2 Sequelae of vitamin C deficiency
0.000 0.515 0.484
E64.1 Sequelae of vitamin A deficiency
0.000 0.515 0.484
E64.0 Sequelae of protein-energy malnutrition
0.000 0.515 0.484
E06 Thyroiditis
0.000 0.522 0.478
E05.8 Other thyrotoxicosis
0.000 0.523 0.477
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.530 0.470
E45 Retarded development following protein-energy malnutrition
0.000 0.530 0.470
E43 Unspecified severe protein-energy malnutrition
0.000 0.530 0.470
E42 Marasmic kwashiorkor
0.000 0.530 0.470
E41 Nutritional marasmus
0.000 0.530 0.470
E40 Kwashiorkor
0.000 0.530 0.470
K51 Ulcerative colitis
0.457 0.543 0.000
E31.9 Polyglandular dysfunction, unspecified
0.000 0.548 0.451
E31.8 Other polyglandular dysfunction
0.000 0.548 0.451
E31.1 Polyglandular hyperfunction
0.000 0.548 0.451
E29.9 Testicular dysfunction, unspecified
0.000 0.552 0.448
E29.8 Other testicular dysfunction
0.000 0.552 0.448
E29.0 Testicular hyperfunction
0.000 0.552 0.448
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.563 0.436
K51.2 Ulcerative (chronic) proctitis
0.435 0.565 0.000
K50 Crohn's disease [regional enteritis]
0.432 0.568 0.000
K51.9 Ulcerative colitis, unspecified
0.432 0.568 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.570 0.430
E22.0 Acromegaly and pituitary gigantism
0.000 0.572 0.428
K50-K52 Noninfective enteritis and colitis
0.427 0.573 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.575 0.425
K50.9 Crohn's disease, unspecified
0.423 0.577 0.000
E34.5 Androgen resistance syndrome
0.000 0.580 0.420
E34.4 Constitutional tall stature
0.000 0.580 0.420
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.580 0.420
E34.1 Other hypersecretion of intestinal hormones
0.000 0.580 0.420
E27.5 Adrenomedullary hyperfunction
0.000 0.581 0.419
E27.0 Other adrenocortical overactivity
0.000 0.581 0.419
K50.0 Crohn's disease of small intestine
0.412 0.588 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.404 0.596 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.598 0.402
E22.8 Other hyperfunction of pituitary gland
0.000 0.598 0.402
K51.8 Other ulcerative colitis
0.400 0.600 0.000
E06.9 Thyroiditis, unspecified
0.000 0.600 0.400
E31.0 Autoimmune polyglandular failure
0.000 0.601 0.398
E29.1 Testicular hypofunction
0.000 0.610 0.390
E34.3 Short stature, not elsewhere classified
0.000 0.610 0.389
E27.8 Other specified disorders of adrenal gland
0.000 0.611 0.389
E14.9 Without complications
0.000 0.614 0.386
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.614 0.385
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.614 0.385
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.614 0.385
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.614 0.385
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.614 0.385
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.614 0.385
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.614 0.385
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.614 0.385
E26.8 Other hyperaldosteronism
0.000 0.615 0.385
E26.1 Secondary hyperaldosteronism
0.000 0.615 0.385
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.616 0.383
E26.9 Hyperaldosteronism, unspecified
0.000 0.620 0.380
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.621 0.379
K51.3 Ulcerative (chronic) rectosigmoiditis
0.377 0.623 0.000
E14.3 With ophthalmic complications
0.000 0.634 0.366
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.638 0.362
K51.4 Pseudopolyposis of colon
0.361 0.639 0.000
K51.5 Mucosal proctocolitis
0.360 0.640 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.641 0.359
E21.4 Other specified disorders of parathyroid gland
0.000 0.645 0.355
K50.8 Other Crohn's disease
0.346 0.654 0.000
E06.1 Subacute thyroiditis
0.000 0.656 0.344
E06.4 Drug-induced thyroiditis
0.000 0.657 0.343
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.657 0.343
E06.0 Acute thyroiditis
0.000 0.657 0.343
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.659 0.341
K90 Intestinal malabsorption
0.001 0.660 0.339
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.661 0.339
E44.1 Mild protein-energy malnutrition
0.000 0.663 0.337
E44.0 Moderate protein-energy malnutrition
0.000 0.663 0.337
E21.2 Other hyperparathyroidism
0.000 0.664 0.336
E34.0 Carcinoid syndrome
0.000 0.668 0.332
E22.1 Hyperprolactinaemia
0.000 0.681 0.318
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.684 0.316
E34.9 Endocrine disorder, unspecified
0.000 0.689 0.311
E67 Other hyperalimentation
0.000 0.692 0.308
E68 Sequelae of hyperalimentation
0.000 0.692 0.308
E06.5 Other chronic thyroiditis
0.000 0.693 0.306
E03 Other hypothyroidism
0.000 0.697 0.303
E21.3 Hyperparathyroidism, unspecified
0.000 0.697 0.303
K51.1 Ulcerative (chronic) ileocolitis
0.302 0.698 0.000
K50.1 Crohn's disease of large intestine
0.296 0.704 0.000
E21.0 Primary hyperparathyroidism
0.000 0.705 0.295
E65 Localised adiposity
0.000 0.715 0.285
E27.2 Addisonian crisis
0.000 0.716 0.284
K90.8 Other intestinal malabsorption
0.001 0.749 0.250
E26.0 Primary hyperaldosteronism
0.001 0.750 0.249
K90.9 Intestinal malabsorption, unspecified
0.000 0.751 0.249
E03.8 Other specified hypothyroidism
0.000 0.755 0.244
K90.3 Pancreatic steatorrhoea
0.001 0.756 0.243
K90.2 Blind loop syndrome, not elsewhere classified
0.001 0.756 0.243
K90.1 Tropical sprue
0.001 0.756 0.243
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.775 0.225
E03.1 Congenital hypothyroidism without goitre
0.000 0.778 0.222
E67.8 Other specified hyperalimentation
0.000 0.779 0.221
E67.3 Hypervitaminosis D
0.000 0.779 0.221
E67.2 Megavitamin-B6 syndrome
0.000 0.779 0.221
E67.1 Hypercarotenaemia
0.000 0.779 0.221
E67.0 Hypervitaminosis A
0.000 0.779 0.221
E03.5 Myxoedema coma
0.000 0.782 0.217
E03.4 Atrophy of thyroid (acquired)
0.000 0.782 0.217
E03.3 Postinfectious hypothyroidism
0.000 0.782 0.217
E11.3 With ophthalmic complications
0.000 0.788 0.212
E06.3 Autoimmune thyroiditis
0.000 0.790 0.210
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.001 0.824 0.175
E11.9 Without complications
0.000 0.835 0.165
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.850 0.150
E83 Disorders of mineral metabolism
0.143 0.853 0.003
E83.3 Disorders of phosphorus metabolism
0.109 0.890 0.001
E83.9 Disorder of mineral metabolism, unspecified
0.103 0.894 0.003
E83.8 Other disorders of mineral metabolism
0.103 0.894 0.003
E83.2 Disorders of zinc metabolism
0.103 0.894 0.003
E83.0 Disorders of copper metabolism
0.103 0.894 0.003
L40.9 Psoriasis, unspecified
0.000 0.898 0.102
E66 Obesity
0.000 0.900 0.100
F45.8 Other somatoform disorders
0.000 0.901 0.099
E83.4 Disorders of magnesium metabolism
0.071 0.928 0.001
E66.1 Drug-induced obesity
0.000 0.928 0.072
E66.0 Obesity due to excess calories
0.000 0.928 0.072
E04 Other non-toxic goitre
0.000 0.932 0.068
L40 Psoriasis
0.000 0.933 0.067
E66.8 Other obesity
0.000 0.940 0.060
L40.5 Arthropathic psoriasis
0.000 0.940 0.060
F45 Somatoform disorders
0.000 0.941 0.059
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.054 0.946 0.000
L43.9 Lichen planus, unspecified
0.000 0.946 0.054
L43 Lichen planus
0.000 0.946 0.054
L40-L45 Papulosquamous disorders
0.000 0.947 0.053
L40.1 Generalised pustular psoriasis
0.000 0.947 0.053
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.947 0.052
E04.8 Other specified non-toxic goitre
0.000 0.951 0.049
K40 Inguinal hernia
0.049 0.951 0.000
L40.2 Acrodermatitis continua
0.000 0.951 0.048
F45.9 Somatoform disorder, unspecified
0.000 0.952 0.048
F45.2 Hypochondriacal disorder
0.000 0.954 0.046
L40.4 Guttate psoriasis
0.000 0.956 0.044
F45.0 Somatisation disorder
0.000 0.956 0.044
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.044 0.956 0.000
F45.4 Persistent somatoform pain disorder
0.000 0.956 0.043
F45.1 Undifferentiated somatoform disorder
0.000 0.958 0.042
L43.8 Other lichen planus
0.000 0.958 0.042
N84.1 Polyp of cervix uteri
0.041 0.959 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.040 0.960 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.040 0.960 0.000
K52 Other non-infective gastro-enteritis and colitis
0.038 0.960 0.001
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.960 0.040
F45.3 Somatoform autonomic dysfunction
0.000 0.961 0.039
L43.3 Subacute (active) lichen planus
0.000 0.961 0.038
L43.2 Lichenoid drug reaction
0.000 0.961 0.038
L43.1 Bullous lichen planus
0.000 0.961 0.038
L43.0 Hypertrophic lichen planus
0.000 0.961 0.038
L41 Parapsoriasis
0.000 0.961 0.038
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.961 0.038
L40.8 Other psoriasis
0.000 0.961 0.038
E70-E90 Metabolic disorders
0.000 0.962 0.038
L44 Other papulosquamous disorders
0.000 0.963 0.037
L40.3 Pustulosis palmaris et plantaris
0.000 0.963 0.037
K43 Ventral hernia
0.037 0.963 0.000
E73 Lactose intolerance
0.000 0.963 0.036
E73.9 Lactose intolerance, unspecified
0.000 0.964 0.036
E04.0 Non-toxic diffuse goitre
0.000 0.964 0.036
K40-K46 Hernia
0.036 0.964 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.035 0.965 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.035 0.965 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.035 0.965 0.000
Z99.1 Dependence on respirator
0.000 0.966 0.034
K41 Femoral hernia
0.033 0.967 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.032 0.967 0.001
L40.0 Psoriasis vulgaris
0.000 0.968 0.032
E74 Other disorders of carbohydrate metabolism
0.000 0.968 0.032
E04.9 Non-toxic goitre, unspecified
0.000 0.969 0.031
M31.6 Other giant cell arteritis
0.000 0.969 0.031
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.030 0.970 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.970 0.030
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.970 0.030
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.971 0.029
L42 Pityriasis rosea
0.000 0.971 0.029
E84 Cystic fibrosis
0.000 0.971 0.029
E79 Disorders of purine and pyrimidine metabolism
0.000 0.971 0.028
L41.9 Parapsoriasis, unspecified
0.000 0.972 0.028
L41.8 Other parapsoriasis
0.000 0.972 0.028
L41.5 Retiform parapsoriasis
0.000 0.972 0.028
L41.4 Large plaque parapsoriasis
0.000 0.972 0.028
L41.3 Small plaque parapsoriasis
0.000 0.972 0.028
L41.2 Lymphomatoid papulosis
0.000 0.972 0.028
L41.1 Pityriasis lichenoides chronica
0.000 0.972 0.028
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.972 0.028
E72 Other disorders of amino-acid metabolism
0.000 0.972 0.027
E77 Disorders of glycoprotein metabolism
0.000 0.972 0.027
E76 Disorders of glycosaminoglycan metabolism
0.000 0.972 0.027
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.972 0.027
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.972 0.027
E70 Disorders of aromatic amino-acid metabolism
0.000 0.973 0.027
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.973 0.027
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.027 0.973 0.000
L44.9 Papulosquamous disorder, unspecified
0.000 0.973 0.026
L44.8 Other specified papulosquamous disorders
0.000 0.973 0.026
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.973 0.026
L44.3 Lichen ruber moniliformis
0.000 0.973 0.026
L44.2 Lichen striatus
0.000 0.973 0.026
L44.1 Lichen nitidus
0.000 0.973 0.026
K43.7 Other and unspecified ventral hernia with gangrene
0.027 0.973 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.027 0.973 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.027 0.973 0.000
K43.4 Parastomal hernia with gangrene
0.027 0.973 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.027 0.973 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.027 0.973 0.000
K43.1 Ventral hernia with gangrene
0.027 0.973 0.000
E73.8 Other lactose intolerance
0.000 0.973 0.026
E73.1 Secondary lactase deficiency
0.000 0.973 0.026
E73.0 Congenital lactase deficiency
0.000 0.973 0.026
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.026 0.974 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.024 0.975 0.001
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.025 0.975 0.000
L44.0 Pityriasis rubra pilaris
0.000 0.975 0.025
E88 Other metabolic disorders
0.000 0.975 0.025
K46 Unspecified abdominal hernia
0.025 0.975 0.000
E74.0 Glycogen storage disease
0.000 0.976 0.024
E85 Amyloidosis
0.000 0.976 0.024
K41.1 Bilateral femoral hernia, with gangrene
0.024 0.976 0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.024 0.976 0.000
E75.5 Other lipid storage disorders
0.000 0.976 0.024
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.024 0.976 0.000
K52.3 Indeterminate colitis
0.023 0.976 0.001
E83.5 Disorders of calcium metabolism
0.023 0.976 0.001
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.977 0.023
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.977 0.023
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.977 0.023
E74.2 Disorders of galactose metabolism
0.000 0.977 0.023
E74.1 Disorders of fructose metabolism
0.000 0.977 0.023
R31 Unspecified haematuria
0.023 0.977 0.000
K90-K93 Other diseases of the digestive system
0.003 0.977 0.019
E84.9 Cystic fibrosis, unspecified
0.000 0.978 0.022
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.978 0.022
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.978 0.022
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.978 0.022
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.978 0.021
E75.6 Lipid storage disorder, unspecified
0.000 0.978 0.021
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.978 0.021
E75.3 Sphingolipidosis, unspecified
0.000 0.978 0.021
E75.2 Other sphingolipidosis
0.000 0.978 0.021
E75.1 Other gangliosidosis
0.000 0.978 0.021
E75.0 GM2 gangliosidosis
0.000 0.978 0.021
E84.8 Cystic fibrosis with other manifestations
0.000 0.979 0.021
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.979 0.021
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.979 0.020
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.979 0.020
E79.1 Lesch-Nyhan syndrome
0.000 0.979 0.020
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.979 0.021
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.979 0.021
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.979 0.020
E85.4 Organ-limited amyloidosis
0.000 0.979 0.020
E72.0 Disorders of amino-acid transport
0.000 0.980 0.020
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.980 0.020
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.980 0.020
E72.5 Disorders of glycine metabolism
0.000 0.980 0.020
E72.4 Disorders of ornithine metabolism
0.000 0.980 0.020
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.980 0.020
E72.2 Disorders of urea cycle metabolism
0.000 0.980 0.020
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.980 0.020
E71.3 Disorders of fatty-acid metabolism
0.000 0.980 0.020
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.980 0.020
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.980 0.020
E71.0 Maple-syrup-urine disease
0.000 0.980 0.020
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.980 0.020
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.980 0.020
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.980 0.020
E76.2 Other mucopolysaccharidoses
0.000 0.980 0.020
E76.1 Mucopolysaccharidosis, type II
0.000 0.980 0.020
E76.0 Mucopolysaccharidosis, type I
0.000 0.980 0.020
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.980 0.020
E77.8 Other disorders of glycoprotein metabolism
0.000 0.980 0.020
E77.1 Defects in glycoprotein degradation
0.000 0.980 0.020
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.980 0.020
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.980 0.020
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.980 0.020
E70.2 Disorders of tyrosine metabolism
0.000 0.980 0.020
E70.1 Other hyperphenylalaninaemias
0.000 0.980 0.020
E70.0 Classical phenylketonuria
0.000 0.980 0.020
E70.3 Albinism
0.000 0.980 0.020
E88.2 Lipomatosis, not elsewhere classified
0.000 0.981 0.019
J38.3 Other diseases of vocal cords
0.019 0.981 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.981 0.018
E88.9 Metabolic disorder, unspecified
0.000 0.982 0.018
K52.1 Toxic gastro-enteritis and colitis
0.017 0.982 0.001
K46.1 Unspecified abdominal hernia with gangrene
0.018 0.982 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.982 0.017
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.982 0.017
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.982 0.017
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.018 0.982 0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.017 0.983 0.000
E85.8 Other amyloidosis
0.000 0.983 0.017
E88.8 Other specified metabolic disorders
0.000 0.983 0.017
K45 Other abdominal hernia
0.016 0.983 0.000
J38.7 Other diseases of larynx
0.017 0.983 0.000
E88.3 Tumour lysis syndrome
0.000 0.983 0.016
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.016 0.984 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.002 0.984 0.014
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.984 0.016
J38.4 Oedema of larynx
0.016 0.984 0.000
Z04.8 Examination and observation for other specified reasons
0.015 0.985 0.000
D25.9 Leiomyoma of uterus, unspecified
0.015 0.985 0.000
E85.3 Secondary systemic amyloidosis
0.000 0.985 0.015
J38.5 Laryngeal spasm
0.015 0.985 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.986 0.014

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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