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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3128854
log Bayes Factor = 35.7731
Chromosome 6   position 29,431,698  (GRCh37) Explore rs3128854 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.007 0.993
E10.9 Without complications
0.000 0.014 0.986
E10.3 With ophthalmic complications
0.000 0.022 0.978
E10.1 With ketoacidosis
0.000 0.029 0.971
E10.2 With renal complications
0.000 0.052 0.948
E11 Non-insulin-dependent diabetes mellitus
0.000 0.060 0.940
E10.4 With neurological complications
0.000 0.061 0.939
E11.2 With renal complications
0.000 0.083 0.917
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.086 0.914
E13 Other specified diabetes mellitus
0.000 0.088 0.912
E50-E64 Other nutritional deficiencies
0.000 0.106 0.894
E10.6 With other specified complications
0.000 0.108 0.892
E10.5 With peripheral circulatory complications
0.000 0.114 0.886
E20-E35 Disorders of other endocrine glands
0.000 0.134 0.866
E23 Hypofunction and other disorders of pituitary gland
0.000 0.157 0.843
E61 Deficiency of other nutrient elements
0.000 0.161 0.838
E13.9 Without complications
0.000 0.168 0.832
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.180 0.820
E24 Cushing's syndrome
0.000 0.181 0.819
E11.0 With coma
0.000 0.184 0.816
E11.5 With peripheral circulatory complications
0.000 0.186 0.814
E53 Deficiency of other B group vitamins
0.000 0.195 0.805
E61.1 Iron deficiency
0.000 0.199 0.801
E23.0 Hypopituitarism
0.000 0.205 0.795
E10.0 With coma
0.000 0.223 0.777
E10.7 With multiple complications
0.000 0.230 0.770
K51 Ulcerative colitis
0.766 0.234 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.247 0.753
K50 Crohn's disease [regional enteritis]
0.746 0.254 0.000
K50.9 Crohn's disease, unspecified
0.742 0.258 0.000
K50-K52 Noninfective enteritis and colitis
0.741 0.259 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.262 0.738
K51.9 Ulcerative colitis, unspecified
0.730 0.270 0.000
E23.2 Diabetes insipidus
0.000 0.275 0.725
E13.3 With ophthalmic complications
0.000 0.278 0.722
E53.8 Deficiency of other specified B group vitamins
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.288 0.712
E11.1 With ketoacidosis
0.000 0.288 0.712
K51.2 Ulcerative (chronic) proctitis
0.709 0.291 0.000
E10.8 With unspecified complications
0.000 0.292 0.708
E55 Vitamin D deficiency
0.000 0.296 0.704
K50.0 Crohn's disease of small intestine
0.703 0.297 0.000
E14 Unspecified diabetes mellitus
0.000 0.301 0.699
E51 Thiamine deficiency
0.000 0.303 0.697
E28 Ovarian dysfunction
0.000 0.305 0.695
E24.2 Drug-induced Cushing's syndrome
0.000 0.309 0.691
E11.6 With other specified complications
0.000 0.311 0.689
K51.8 Other ulcerative colitis
0.688 0.312 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.316 0.684
E20 Hypoparathyroidism
0.000 0.316 0.683
E16.1 Other hypoglycaemia
0.000 0.319 0.681
K51.0 Ulcerative (chronic) enterocolitis
0.681 0.319 0.000
E11.7 With multiple complications
0.000 0.326 0.674
E24.9 Cushing's syndrome, unspecified
0.000 0.329 0.671
E56 Other vitamin deficiencies
0.000 0.330 0.670
K51.3 Ulcerative (chronic) rectosigmoiditis
0.669 0.331 0.000
E11.8 With unspecified complications
0.000 0.342 0.658
E13.8 With unspecified complications
0.000 0.346 0.654
E13.7 With multiple complications
0.000 0.346 0.654
E13.6 With other specified complications
0.000 0.346 0.654
E13.5 With peripheral circulatory complications
0.000 0.346 0.654
E13.4 With neurological complications
0.000 0.346 0.654
E13.2 With renal complications
0.000 0.346 0.654
E13.1 With ketoacidosis
0.000 0.346 0.654
E13.0 With coma
0.000 0.346 0.654
E11.4 With neurological complications
0.000 0.350 0.650
K51.5 Mucosal proctocolitis
0.646 0.354 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.358 0.642
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.359 0.641
E63 Other nutritional deficiencies
0.000 0.359 0.641
E50 Vitamin A deficiency
0.000 0.359 0.641
E60 Dietary zinc deficiency
0.000 0.359 0.641
E59 Dietary selenium deficiency
0.000 0.359 0.641
E54 Ascorbic acid deficiency
0.000 0.359 0.641
E52 Niacin deficiency [pellagra]
0.000 0.359 0.641
E40-E46 Malnutrition
0.000 0.375 0.625
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.379 0.621
E32 Diseases of thymus
0.000 0.379 0.621
E30 Disorders of puberty, not elsewhere classified
0.000 0.379 0.621
E25 Adrenogenital disorders
0.000 0.379 0.621
K51.4 Pseudopolyposis of colon
0.615 0.385 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.385 0.615
E14.5 With peripheral circulatory complications
0.000 0.389 0.611
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.395 0.604
E23.1 Drug-induced hypopituitarism
0.000 0.395 0.604
E61.9 Deficiency of nutrient element, unspecified
0.000 0.399 0.601
E61.8 Deficiency of other specified nutrient elements
0.000 0.399 0.601
E61.7 Deficiency of multiple nutrient elements
0.000 0.399 0.601
E61.6 Vanadium deficiency
0.000 0.399 0.601
E61.5 Molybdenum deficiency
0.000 0.399 0.601
E61.4 Chromium deficiency
0.000 0.399 0.601
E61.3 Manganese deficiency
0.000 0.399 0.601
E61.0 Copper deficiency
0.000 0.399 0.601
E28.3 Primary ovarian failure
0.000 0.406 0.594
E23.6 Other disorders of pituitary gland
0.000 0.408 0.592
E61.2 Magnesium deficiency
0.000 0.412 0.588
E15 Nondiabetic hypoglycaemic coma
0.000 0.412 0.588
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.413 0.587
E24.3 Ectopic ACTH syndrome
0.000 0.413 0.587
E24.1 Nelson's syndrome
0.000 0.413 0.587
E53.1 Pyridoxine deficiency
0.000 0.423 0.577
E53.0 Riboflavin deficiency
0.000 0.423 0.577
E31 Polyglandular dysfunction
0.000 0.427 0.573
E55.9 Vitamin D deficiency, unspecified
0.000 0.432 0.568
K50.8 Other Crohn's disease
0.566 0.433 0.000
E29 Testicular dysfunction
0.000 0.442 0.557
E51.2 Wernicke's encephalopathy
0.000 0.444 0.556
E34 Other endocrine disorders
0.000 0.446 0.554
E20.9 Hypoparathyroidism, unspecified
0.000 0.447 0.553
E14.4 With neurological complications
0.000 0.455 0.545
E24.8 Other Cushing's syndrome
0.000 0.455 0.545
E14.1 With ketoacidosis
0.000 0.456 0.544
E58 Dietary calcium deficiency
0.000 0.458 0.542
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.460 0.540
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.460 0.540
E16.4 Abnormal secretion of gastrin
0.000 0.460 0.540
E16.3 Increased secretion of glucagon
0.000 0.460 0.540
E27 Other disorders of adrenal gland
0.000 0.468 0.532
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.469 0.531
K50.1 Crohn's disease of large intestine
0.527 0.473 0.000
E14.6 With other specified complications
0.000 0.482 0.518
E12.9 Without complications
0.000 0.489 0.511
E12.8 With unspecified complications
0.000 0.489 0.511
E12.7 With multiple complications
0.000 0.489 0.511
E12.6 With other specified complications
0.000 0.489 0.511
E12.5 With peripheral circulatory complications
0.000 0.489 0.511
E12.4 With neurological complications
0.000 0.489 0.511
E12.3 With ophthalmic complications
0.000 0.489 0.511
E12.2 With renal complications
0.000 0.489 0.511
E12.1 With ketoacidosis
0.000 0.489 0.511
E12.0 With coma
0.000 0.489 0.511
E56.1 Deficiency of vitamin K
0.000 0.490 0.510
E00-E07 Disorders of thyroid gland
0.000 0.493 0.507
E55.0 Rickets, active
0.000 0.495 0.505
E14.7 With multiple complications
0.000 0.499 0.501
E14.0 With coma
0.000 0.499 0.501
K51.1 Ulcerative (chronic) ileocolitis
0.501 0.499 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.500 0.500
E51.8 Other manifestations of thiamine deficiency
0.000 0.500 0.500
E51.1 Beriberi
0.000 0.500 0.500
E28.9 Ovarian dysfunction, unspecified
0.000 0.501 0.498
E28.8 Other ovarian dysfunction
0.000 0.501 0.498
E28.1 Androgen excess
0.000 0.501 0.498
E28.0 Oestrogen excess
0.000 0.501 0.498
E20.8 Other hypoparathyroidism
0.000 0.510 0.490
E20.1 Pseudohypoparathyroidism
0.000 0.510 0.490
E20.0 Idiopathic hypoparathyroidism
0.000 0.510 0.490
E34.8 Other specified endocrine disorders
0.000 0.513 0.487
E27.1 Primary adrenocortical insufficiency
0.000 0.514 0.486
E14.2 Withrenal complications
0.000 0.518 0.482
E56.9 Vitamin deficiency, unspecified
0.000 0.519 0.480
E56.8 Deficiency of other vitamins
0.000 0.519 0.480
E56.0 Deficiency of vitamin E
0.000 0.519 0.480
E14.8 With unspecified complications
0.000 0.522 0.477
E07 Other disorders of thyroid
0.000 0.539 0.461
E50.9 Vitamin A deficiency, unspecified
0.000 0.540 0.460
E50.8 Other manifestations of vitamin A deficiency
0.000 0.540 0.460
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.540 0.460
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.540 0.460
E50.5 Vitamin A deficiency with night blindness
0.000 0.540 0.460
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.540 0.460
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.540 0.460
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.540 0.460
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.540 0.460
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.540 0.460
E63.9 Nutritional deficiency, unspecified
0.000 0.540 0.460
E63.8 Other specified nutritional deficiencies
0.000 0.540 0.460
E63.1 Imbalance of constituents of food intake
0.000 0.540 0.460
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.540 0.460
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.540 0.460
E64.8 Sequelae of other nutritional deficiencies
0.000 0.540 0.460
E64.3 Sequelae of rickets
0.000 0.540 0.460
E64.2 Sequelae of vitamin C deficiency
0.000 0.540 0.460
E64.1 Sequelae of vitamin A deficiency
0.000 0.540 0.460
E64.0 Sequelae of protein-energy malnutrition
0.000 0.540 0.460
E28.2 Polycystic ovarian syndrome
0.000 0.543 0.456
E26 Hyperaldosteronism
0.000 0.544 0.456
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.552 0.448
E45 Retarded development following protein-energy malnutrition
0.000 0.552 0.448
E43 Unspecified severe protein-energy malnutrition
0.000 0.552 0.448
E42 Marasmic kwashiorkor
0.000 0.552 0.448
E41 Nutritional marasmus
0.000 0.552 0.448
E40 Kwashiorkor
0.000 0.552 0.448
E22 Hyperfunction of pituitary gland
0.000 0.553 0.447
E25.9 Adrenogenital disorder, unspecified
0.000 0.555 0.445
E25.8 Other adrenogenital disorders
0.000 0.555 0.445
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.555 0.445
E30.9 Disorder of puberty, unspecified
0.000 0.555 0.445
E30.8 Other disorders of puberty
0.000 0.555 0.445
E30.1 Precocious puberty
0.000 0.555 0.445
E30.0 Delayed puberty
0.000 0.555 0.445
E32.9 Disease of thymus, unspecified
0.000 0.555 0.445
E32.8 Other diseases of thymus
0.000 0.555 0.445
E32.1 Abscess of thymus
0.000 0.555 0.445
E32.0 Persistent hyperplasia of thymus
0.000 0.555 0.445
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.555 0.445
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.555 0.445
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.555 0.445
E07.8 Other specified disorders of thyroid
0.000 0.580 0.420
E46 Unspecified protein-energy malnutrition
0.000 0.583 0.417
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.586 0.414
E31.9 Polyglandular dysfunction, unspecified
0.000 0.589 0.411
E31.8 Other polyglandular dysfunction
0.000 0.589 0.411
E31.1 Polyglandular hyperfunction
0.000 0.589 0.411
E29.9 Testicular dysfunction, unspecified
0.000 0.600 0.400
E29.8 Other testicular dysfunction
0.000 0.600 0.400
E29.0 Testicular hyperfunction
0.000 0.600 0.400
E65-E68 Obesity and other hyperalimentation
0.000 0.601 0.399
E34.5 Androgen resistance syndrome
0.000 0.603 0.397
E34.4 Constitutional tall stature
0.000 0.603 0.397
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.603 0.397
E34.1 Other hypersecretion of intestinal hormones
0.000 0.603 0.397
E27.5 Adrenomedullary hyperfunction
0.000 0.618 0.382
E27.0 Other adrenocortical overactivity
0.000 0.618 0.382
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.619 0.381
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.633 0.367
K90 Intestinal malabsorption
0.000 0.636 0.364
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.636 0.364
E00 Congenital iodine-deficiency syndrome
0.000 0.636 0.364
E31.0 Autoimmune polyglandular failure
0.000 0.637 0.362
E27.8 Other specified disorders of adrenal gland
0.000 0.639 0.361
E07.9 Disorder of thyroid, unspecified
0.000 0.644 0.356
E34.3 Short stature, not elsewhere classified
0.000 0.648 0.352
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.652 0.348
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.653 0.346
E29.1 Testicular hypofunction
0.000 0.664 0.336
E14.3 With ophthalmic complications
0.000 0.667 0.333
E05.9 Thyrotoxicosis, unspecified
0.000 0.668 0.332
E07.1 Dyshormogenetic goitre
0.000 0.669 0.331
E07.0 Hypersecretion of calcitonin
0.000 0.669 0.331
E14.9 Without complications
0.000 0.672 0.328
E26.8 Other hyperaldosteronism
0.000 0.673 0.327
E26.1 Secondary hyperaldosteronism
0.000 0.673 0.327
E06 Thyroiditis
0.000 0.676 0.324
E26.9 Hyperaldosteronism, unspecified
0.000 0.677 0.323
E44.1 Mild protein-energy malnutrition
0.000 0.679 0.321
E44.0 Moderate protein-energy malnutrition
0.000 0.679 0.321
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.679 0.321
E22.8 Other hyperfunction of pituitary gland
0.000 0.679 0.321
E27.9 Disorder of adrenal gland, unspecified
0.000 0.683 0.317
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.683 0.317
E22.0 Acromegaly and pituitary gigantism
0.000 0.685 0.315
E34.9 Endocrine disorder, unspecified
0.000 0.695 0.304
E34.0 Carcinoid syndrome
0.000 0.700 0.300
E05.5 Thyroid crisis or storm
0.000 0.703 0.297
E05.4 Thyrotoxicosis factitia
0.000 0.703 0.297
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.703 0.297
E05.8 Other thyrotoxicosis
0.000 0.709 0.291
E67 Other hyperalimentation
0.000 0.714 0.286
E68 Sequelae of hyperalimentation
0.000 0.714 0.286
K90.9 Intestinal malabsorption, unspecified
0.000 0.715 0.284
E06.9 Thyroiditis, unspecified
0.000 0.724 0.275
E21.4 Other specified disorders of parathyroid gland
0.000 0.727 0.273
E65 Localised adiposity
0.000 0.727 0.273
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.730 0.270
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.734 0.266
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.736 0.264
K90.8 Other intestinal malabsorption
0.000 0.736 0.263
K90.3 Pancreatic steatorrhoea
0.000 0.739 0.261
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.739 0.261
K90.1 Tropical sprue
0.000 0.739 0.261
E27.2 Addisonian crisis
0.000 0.739 0.261
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.739 0.261
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.739 0.261
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.739 0.261
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.739 0.261
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.739 0.261
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.739 0.261
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.739 0.261
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.739 0.261
E21.2 Other hyperparathyroidism
0.000 0.741 0.259
E22.1 Hyperprolactinaemia
0.000 0.743 0.257
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.743 0.257
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.761 0.239
E06.1 Subacute thyroiditis
0.000 0.766 0.234
E06.4 Drug-induced thyroiditis
0.000 0.767 0.233
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.767 0.233
E06.0 Acute thyroiditis
0.000 0.767 0.233
E21.0 Primary hyperparathyroidism
0.000 0.789 0.211
E21.3 Hyperparathyroidism, unspecified
0.000 0.794 0.206
E67.8 Other specified hyperalimentation
0.000 0.794 0.205
E67.3 Hypervitaminosis D
0.000 0.794 0.205
E67.2 Megavitamin-B6 syndrome
0.000 0.794 0.205
E67.1 Hypercarotenaemia
0.000 0.794 0.205
E67.0 Hypervitaminosis A
0.000 0.794 0.205
E11.3 With ophthalmic complications
0.000 0.795 0.205
E03 Other hypothyroidism
0.000 0.806 0.194
E06.5 Other chronic thyroiditis
0.000 0.809 0.190
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.001 0.817 0.183
E83 Disorders of mineral metabolism
0.178 0.820 0.002
E26.0 Primary hyperaldosteronism
0.001 0.828 0.171
E11.9 Without complications
0.000 0.831 0.169
E06.3 Autoimmune thyroiditis
0.000 0.845 0.155
E03.8 Other specified hypothyroidism
0.000 0.845 0.155
E03.1 Congenital hypothyroidism without goitre
0.000 0.857 0.143
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.860 0.140
E03.5 Myxoedema coma
0.000 0.861 0.139
E03.4 Atrophy of thyroid (acquired)
0.000 0.861 0.139
E03.3 Postinfectious hypothyroidism
0.000 0.861 0.139
E83.3 Disorders of phosphorus metabolism
0.135 0.864 0.001
E83.9 Disorder of mineral metabolism, unspecified
0.128 0.871 0.001
E83.8 Other disorders of mineral metabolism
0.128 0.871 0.001
E83.2 Disorders of zinc metabolism
0.128 0.871 0.001
E83.0 Disorders of copper metabolism
0.128 0.871 0.001
F45.8 Other somatoform disorders
0.000 0.880 0.120
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.903 0.097
E83.4 Disorders of magnesium metabolism
0.093 0.906 0.001
L40.9 Psoriasis, unspecified
0.000 0.919 0.081
E66 Obesity
0.000 0.931 0.069
K52 Other non-infective gastro-enteritis and colitis
0.066 0.933 0.001
F45 Somatoform disorders
0.000 0.934 0.066
L40 Psoriasis
0.000 0.936 0.064
L40.5 Arthropathic psoriasis
0.000 0.938 0.062
E83.5 Disorders of calcium metabolism
0.057 0.943 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.056 0.944 0.001
Z99.1 Dependence on respirator
0.000 0.946 0.054
F45.9 Somatoform disorder, unspecified
0.000 0.946 0.054
F45.2 Hypochondriacal disorder
0.000 0.948 0.052
L40.1 Generalised pustular psoriasis
0.000 0.949 0.051
E04 Other non-toxic goitre
0.000 0.950 0.050
E66.0 Obesity due to excess calories
0.000 0.950 0.050
E66.1 Drug-induced obesity
0.000 0.950 0.050
F45.0 Somatisation disorder
0.000 0.950 0.050
F45.4 Persistent somatoform pain disorder
0.000 0.951 0.049
L40-L45 Papulosquamous disorders
0.000 0.952 0.048
F45.1 Undifferentiated somatoform disorder
0.000 0.952 0.048
L43 Lichen planus
0.000 0.953 0.047
L43.9 Lichen planus, unspecified
0.000 0.953 0.047
L40.2 Acrodermatitis continua
0.000 0.954 0.046
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.956 0.044
K52.3 Indeterminate colitis
0.042 0.957 0.001
L40.4 Guttate psoriasis
0.000 0.958 0.042
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.039 0.960 0.001
F45.3 Somatoform autonomic dysfunction
0.000 0.961 0.038
L43.8 Other lichen planus
0.000 0.962 0.037
L40.8 Other psoriasis
0.000 0.963 0.037
E04.8 Other specified non-toxic goitre
0.000 0.964 0.036
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.964 0.036
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.964 0.035
L40.3 Pustulosis palmaris et plantaris
0.000 0.965 0.035
L41 Parapsoriasis
0.000 0.965 0.035
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.965 0.035
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.965 0.034
L43.3 Subacute (active) lichen planus
0.000 0.966 0.034
L43.2 Lichenoid drug reaction
0.000 0.966 0.034
L43.1 Bullous lichen planus
0.000 0.966 0.034
L43.0 Hypertrophic lichen planus
0.000 0.966 0.034
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.034 0.966 0.000
L44 Other papulosquamous disorders
0.000 0.967 0.033
M31.6 Other giant cell arteritis
0.000 0.969 0.031
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.030 0.970 0.000
E66.8 Other obesity
0.000 0.971 0.029
L40.0 Psoriasis vulgaris
0.000 0.971 0.029
K52.1 Toxic gastro-enteritis and colitis
0.026 0.973 0.001
E04.9 Non-toxic goitre, unspecified
0.000 0.973 0.027
L42 Pityriasis rosea
0.000 0.974 0.026
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.974 0.026
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.974 0.026
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.974 0.026
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.974 0.026
E04.0 Non-toxic diffuse goitre
0.000 0.975 0.025
K40 Inguinal hernia
0.025 0.975 0.000
L41.9 Parapsoriasis, unspecified
0.000 0.975 0.025
L41.8 Other parapsoriasis
0.000 0.975 0.025
L41.5 Retiform parapsoriasis
0.000 0.975 0.025
L41.4 Large plaque parapsoriasis
0.000 0.975 0.025
L41.3 Small plaque parapsoriasis
0.000 0.975 0.025
L41.2 Lymphomatoid papulosis
0.000 0.975 0.025
L41.1 Pityriasis lichenoides chronica
0.000 0.975 0.025
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.975 0.025
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.976 0.024
L44.9 Papulosquamous disorder, unspecified
0.000 0.976 0.024
L44.8 Other specified papulosquamous disorders
0.000 0.976 0.024
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.976 0.024
L44.3 Lichen ruber moniliformis
0.000 0.976 0.024
L44.2 Lichen striatus
0.000 0.976 0.024
L44.1 Lichen nitidus
0.000 0.976 0.024
E70-E90 Metabolic disorders
0.001 0.976 0.023
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.023 0.977 0.000
E73 Lactose intolerance
0.000 0.977 0.023
E73.9 Lactose intolerance, unspecified
0.000 0.977 0.023
L44.0 Pityriasis rubra pilaris
0.000 0.977 0.022
K90-K93 Other diseases of the digestive system
0.002 0.978 0.021
Z99.8 Dependence on other enabling machines and devices
0.000 0.978 0.022
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.978 0.022
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.021 0.979 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.021 0.979 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.980 0.019
K40.1 Bilateral inguinal hernia, with gangrene
0.018 0.982 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.982 0.018
E84 Cystic fibrosis
0.001 0.982 0.018
E79 Disorders of purine and pyrimidine metabolism
0.001 0.982 0.018
E72 Other disorders of amino-acid metabolism
0.001 0.983 0.017
E77 Disorders of glycoprotein metabolism
0.001 0.983 0.017
E76 Disorders of glycosaminoglycan metabolism
0.001 0.983 0.017
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.983 0.017
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.983 0.017
E70 Disorders of aromatic amino-acid metabolism
0.001 0.983 0.017
E73.8 Other lactose intolerance
0.000 0.983 0.016
E73.1 Secondary lactase deficiency
0.000 0.983 0.016
E73.0 Congenital lactase deficiency
0.000 0.983 0.016
M31 Other necrotising vasculopathies
0.000 0.984 0.016
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.984 0.015
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.984 0.016
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.984 0.016
Z99.4 Dependence on artificial heart
0.000 0.984 0.016
Z99.0 Dependence on aspirator
0.000 0.984 0.015
E74.0 Glycogen storage disease
0.000 0.985 0.015
M31.0 Hypersensitivity angiitis
0.000 0.985 0.015
E88 Other metabolic disorders
0.000 0.985 0.014
E85 Amyloidosis
0.001 0.986 0.014
E75.5 Other lipid storage disorders
0.000 0.986 0.014
N84.1 Polyp of cervix uteri
0.014 0.986 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.014 0.986 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.986 0.014
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.986 0.014
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.986 0.014
E74.2 Disorders of galactose metabolism
0.000 0.986 0.014
E74.1 Disorders of fructose metabolism
0.000 0.986 0.014
E84.9 Cystic fibrosis, unspecified
0.000 0.986 0.014
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.986 0.014
R31 Unspecified haematuria
0.014 0.986 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.986 0.014
E75.6 Lipid storage disorder, unspecified
0.001 0.987 0.013
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.987 0.013
E75.3 Sphingolipidosis, unspecified
0.001 0.987 0.013
E75.2 Other sphingolipidosis
0.001 0.987 0.013
E75.1 Other gangliosidosis
0.001 0.987 0.013
E75.0 GM2 gangliosidosis
0.001 0.987 0.013
E84.8 Cystic fibrosis with other manifestations
0.001 0.987 0.013
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.987 0.013
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.987 0.013
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.987 0.013
E79.1 Lesch-Nyhan syndrome
0.001 0.987 0.013
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.987 0.013
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.987 0.013
Z04.8 Examination and observation for other specified reasons
0.013 0.987 0.000
E72.0 Disorders of amino-acid transport
0.001 0.987 0.012
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.987 0.012
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.987 0.012
E72.5 Disorders of glycine metabolism
0.001 0.987 0.012
E72.4 Disorders of ornithine metabolism
0.001 0.987 0.012
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.987 0.012
E72.2 Disorders of urea cycle metabolism
0.001 0.987 0.012
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.987 0.012
E71.3 Disorders of fatty-acid metabolism
0.001 0.987 0.012
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.987 0.012
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.987 0.012
E71.0 Maple-syrup-urine disease
0.001 0.987 0.012
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.987 0.012
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.987 0.012
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.987 0.012
E76.2 Other mucopolysaccharidoses
0.001 0.987 0.012
E76.1 Mucopolysaccharidosis, type II
0.001 0.987 0.012
E76.0 Mucopolysaccharidosis, type I
0.001 0.987 0.012
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.987 0.012
E77.8 Other disorders of glycoprotein metabolism
0.001 0.987 0.012
E77.1 Defects in glycoprotein degradation
0.001 0.987 0.012
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.987 0.012
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.987 0.012
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.987 0.012
E70.2 Disorders of tyrosine metabolism
0.001 0.987 0.012
E70.1 Other hyperphenylalaninaemias
0.001 0.987 0.012
E70.0 Classical phenylketonuria
0.001 0.987 0.012
E70.3 Albinism
0.001 0.987 0.012
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.987 0.013
K40-K46 Hernia
0.013 0.987 0.000
K43 Ventral hernia
0.012 0.987 0.000
M31.7 Microscopic polyangiitis
0.000 0.988 0.012
M31.9 Necrotising vasculopathy, unspecified
0.000 0.988 0.012
K41 Femoral hernia
0.012 0.988 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.012 0.988 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.012 0.988 0.000
I83 Varicose veins of lower extremities
0.012 0.988 0.000
M31.8 Other specified necrotising vasculopathies
0.000 0.988 0.012
M31.2 Lethal midline granuloma
0.000 0.988 0.012
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.988 0.011
K93.1 Megacolon in Chagas' disease
0.001 0.988 0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.988 0.011
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.012 0.988 0.000
E85.4 Organ-limited amyloidosis
0.000 0.988 0.011
K43.9 Ventral hernia without obstruction or gangrene
0.012 0.988 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.989 0.011
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.011 0.989 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.011 0.989 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.989 0.011
E04.2 Non-toxic multinodular goitre
0.000 0.989 0.011
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.989 0.010
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.989 0.010
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.989 0.010
M31.1 Thrombotic microangiopathy
0.000 0.989 0.010
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.010 0.989 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.990 0.010
E85.8 Other amyloidosis
0.001 0.990 0.010
E88.8 Other specified metabolic disorders
0.000 0.990 0.010
I83.1 Varicose veins of lower extremities with inflammation
0.010 0.990 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.010 0.990 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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