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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3128918
log Bayes Factor = 14.8914
Chromosome 6   position 33,061,098  (GRCh37) Explore rs3128918 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E16.2 Hypoglycaemia, unspecified
0.000 0.011 0.989
E16 Other disorders of pancreatic internal secretion
0.000 0.015 0.985
E11 Non-insulin-dependent diabetes mellitus
0.000 0.017 0.983
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.018 0.982
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.019 0.981
E10.1 With ketoacidosis
0.000 0.021 0.979
E11.2 With renal complications
0.000 0.053 0.947
E11.3 With ophthalmic complications
0.000 0.070 0.930
E10.4 With neurological complications
0.000 0.073 0.927
E11.1 With ketoacidosis
0.000 0.089 0.911
E10.2 With renal complications
0.000 0.122 0.878
E20-E35 Disorders of other endocrine glands
0.000 0.147 0.853
K90.0 Coeliac disease
0.000 0.155 0.845
E11.4 With neurological complications
0.000 0.168 0.832
E10.5 With peripheral circulatory complications
0.000 0.176 0.824
E27 Other disorders of adrenal gland
0.000 0.197 0.803
E10.8 With unspecified complications
0.000 0.202 0.798
E10.0 With coma
0.000 0.225 0.775
E16.1 Other hypoglycaemia
0.000 0.233 0.767
E34 Other endocrine disorders
0.000 0.241 0.759
E27.1 Primary adrenocortical insufficiency
0.000 0.258 0.742
E22 Hyperfunction of pituitary gland
0.000 0.273 0.727
E50-E64 Other nutritional deficiencies
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E20 Hypoparathyroidism
0.000 0.293 0.707
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.294 0.706
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.294 0.706
E16.4 Abnormal secretion of gastrin
0.000 0.294 0.706
E16.3 Increased secretion of glucagon
0.000 0.294 0.706
E11.7 With multiple complications
0.000 0.295 0.705
E15 Nondiabetic hypoglycaemic coma
0.000 0.296 0.704
E11.0 With coma
0.000 0.311 0.689
E11.6 With other specified complications
0.000 0.324 0.676
E34.9 Endocrine disorder, unspecified
0.000 0.333 0.667
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.350 0.650
E27.9 Disorder of adrenal gland, unspecified
0.000 0.364 0.636
E27.8 Other specified disorders of adrenal gland
0.000 0.374 0.626
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.375 0.625
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.388 0.612
E32 Diseases of thymus
0.000 0.388 0.612
E31 Polyglandular dysfunction
0.000 0.388 0.612
E30 Disorders of puberty, not elsewhere classified
0.000 0.388 0.612
E53 Deficiency of other B group vitamins
0.000 0.395 0.605
E22.0 Acromegaly and pituitary gigantism
0.000 0.397 0.603
E20.9 Hypoparathyroidism, unspecified
0.000 0.398 0.602
E26 Hyperaldosteronism
0.000 0.398 0.602
E34.0 Carcinoid syndrome
0.000 0.402 0.598
E11.8 With unspecified complications
0.000 0.416 0.584
E14 Unspecified diabetes mellitus
0.000 0.421 0.579
E27.5 Adrenomedullary hyperfunction
0.000 0.424 0.576
E27.0 Other adrenocortical overactivity
0.000 0.424 0.576
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.427 0.573
E70-E90 Metabolic disorders
0.000 0.439 0.561
E25 Adrenogenital disorders
0.000 0.446 0.554
E83.1 Disorders of iron metabolism
0.000 0.446 0.554
E83 Disorders of mineral metabolism
0.000 0.449 0.551
E34.8 Other specified endocrine disorders
0.000 0.450 0.550
E27.2 Addisonian crisis
0.000 0.453 0.547
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.455 0.545
E34.5 Androgen resistance syndrome
0.000 0.456 0.544
E34.4 Constitutional tall stature
0.000 0.456 0.544
E34.3 Short stature, not elsewhere classified
0.000 0.456 0.544
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.456 0.544
E34.1 Other hypersecretion of intestinal hormones
0.000 0.456 0.544
E53.8 Deficiency of other specified B group vitamins
0.000 0.458 0.542
E28 Ovarian dysfunction
0.000 0.460 0.540
E22.1 Hyperprolactinaemia
0.000 0.474 0.526
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.479 0.521
E22.8 Other hyperfunction of pituitary gland
0.000 0.479 0.521
E40-E46 Malnutrition
0.000 0.482 0.517
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.485 0.515
E63 Other nutritional deficiencies
0.000 0.485 0.515
E56 Other vitamin deficiencies
0.000 0.485 0.515
E51 Thiamine deficiency
0.000 0.485 0.515
E50 Vitamin A deficiency
0.000 0.485 0.515
E60 Dietary zinc deficiency
0.000 0.485 0.515
E59 Dietary selenium deficiency
0.000 0.485 0.515
E58 Dietary calcium deficiency
0.000 0.485 0.515
E54 Ascorbic acid deficiency
0.000 0.485 0.515
E52 Niacin deficiency [pellagra]
0.000 0.485 0.515
E12.9 Without complications
0.000 0.487 0.512
E12.8 With unspecified complications
0.000 0.487 0.512
E12.7 With multiple complications
0.000 0.487 0.512
E12.6 With other specified complications
0.000 0.487 0.512
E12.5 With peripheral circulatory complications
0.000 0.487 0.512
E12.4 With neurological complications
0.000 0.487 0.512
E12.3 With ophthalmic complications
0.000 0.487 0.512
E12.2 With renal complications
0.000 0.487 0.512
E12.1 With ketoacidosis
0.000 0.487 0.512
E12.0 With coma
0.000 0.487 0.512
E29 Testicular dysfunction
0.000 0.491 0.509
E20.8 Other hypoparathyroidism
0.000 0.493 0.507
E20.1 Pseudohypoparathyroidism
0.000 0.493 0.507
E20.0 Idiopathic hypoparathyroidism
0.000 0.493 0.507
E13 Other specified diabetes mellitus
0.001 0.495 0.505
E11.5 With peripheral circulatory complications
0.000 0.503 0.497
E55 Vitamin D deficiency
0.000 0.518 0.482
E26.0 Primary hyperaldosteronism
0.000 0.521 0.479
E23 Hypofunction and other disorders of pituitary gland
0.000 0.533 0.467
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.549 0.451
E30.9 Disorder of puberty, unspecified
0.000 0.561 0.438
E30.8 Other disorders of puberty
0.000 0.561 0.438
E30.1 Precocious puberty
0.000 0.561 0.438
E30.0 Delayed puberty
0.000 0.561 0.438
E31.9 Polyglandular dysfunction, unspecified
0.000 0.561 0.438
E31.8 Other polyglandular dysfunction
0.000 0.561 0.438
E31.1 Polyglandular hyperfunction
0.000 0.561 0.438
E31.0 Autoimmune polyglandular failure
0.000 0.561 0.438
E32.9 Disease of thymus, unspecified
0.000 0.561 0.438
E32.8 Other diseases of thymus
0.000 0.561 0.438
E32.1 Abscess of thymus
0.000 0.561 0.438
E32.0 Persistent hyperplasia of thymus
0.000 0.561 0.438
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.561 0.438
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.561 0.438
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.561 0.438
E53.1 Pyridoxine deficiency
0.000 0.566 0.434
E53.0 Riboflavin deficiency
0.000 0.566 0.434
E14.4 With neurological complications
0.000 0.567 0.433
E26.8 Other hyperaldosteronism
0.000 0.568 0.431
E26.1 Secondary hyperaldosteronism
0.000 0.568 0.431
E83.4 Disorders of magnesium metabolism
0.000 0.574 0.426
E61 Deficiency of other nutrient elements
0.000 0.574 0.425
E14.7 With multiple complications
0.000 0.585 0.415
E14.6 With other specified complications
0.000 0.585 0.415
E14.5 With peripheral circulatory complications
0.000 0.585 0.415
E14.2 Withrenal complications
0.000 0.585 0.415
E14.1 With ketoacidosis
0.000 0.585 0.415
E14.0 With coma
0.000 0.585 0.415
E84 Cystic fibrosis
0.000 0.598 0.402
E79 Disorders of purine and pyrimidine metabolism
0.000 0.598 0.402
E77 Disorders of glycoprotein metabolism
0.000 0.598 0.402
E76 Disorders of glycosaminoglycan metabolism
0.000 0.598 0.402
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.598 0.402
E72 Other disorders of amino-acid metabolism
0.000 0.598 0.402
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.598 0.402
E70 Disorders of aromatic amino-acid metabolism
0.000 0.598 0.402
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.598 0.402
E14.3 With ophthalmic complications
0.000 0.602 0.398
E25.9 Adrenogenital disorder, unspecified
0.000 0.603 0.397
E25.8 Other adrenogenital disorders
0.000 0.603 0.397
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.605 0.395
E83.8 Other disorders of mineral metabolism
0.000 0.605 0.395
E83.2 Disorders of zinc metabolism
0.000 0.605 0.395
E83.0 Disorders of copper metabolism
0.000 0.605 0.395
E28.3 Primary ovarian failure
0.000 0.605 0.395
E24 Cushing's syndrome
0.001 0.605 0.394
E85 Amyloidosis
0.000 0.608 0.392
E14.8 With unspecified complications
0.000 0.608 0.392
E74 Other disorders of carbohydrate metabolism
0.000 0.611 0.389
E53.9 Vitamin B deficiency, unspecified
0.000 0.612 0.387
E28.9 Ovarian dysfunction, unspecified
0.000 0.612 0.387
E28.8 Other ovarian dysfunction
0.000 0.612 0.387
E28.1 Androgen excess
0.000 0.612 0.387
E28.0 Oestrogen excess
0.000 0.612 0.387
E89.3 Postprocedural hypopituitarism
0.000 0.620 0.380
K90 Intestinal malabsorption
0.000 0.623 0.377
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.629 0.371
E45 Retarded development following protein-energy malnutrition
0.001 0.629 0.371
E43 Unspecified severe protein-energy malnutrition
0.001 0.629 0.371
E42 Marasmic kwashiorkor
0.001 0.629 0.371
E41 Nutritional marasmus
0.001 0.629 0.371
E40 Kwashiorkor
0.001 0.629 0.371
E50.9 Vitamin A deficiency, unspecified
0.000 0.631 0.369
E50.8 Other manifestations of vitamin A deficiency
0.000 0.631 0.369
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.631 0.369
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.631 0.369
E50.5 Vitamin A deficiency with night blindness
0.000 0.631 0.369
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.631 0.369
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.631 0.369
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.631 0.369
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.631 0.369
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.631 0.369
E51.9 Thiamine deficiency, unspecified
0.000 0.631 0.369
E51.8 Other manifestations of thiamine deficiency
0.000 0.631 0.369
E51.2 Wernicke's encephalopathy
0.000 0.631 0.369
E51.1 Beriberi
0.000 0.631 0.369
E56.9 Vitamin deficiency, unspecified
0.000 0.631 0.369
E56.8 Deficiency of other vitamins
0.000 0.631 0.369
E56.1 Deficiency of vitamin K
0.000 0.631 0.369
E56.0 Deficiency of vitamin E
0.000 0.631 0.369
E63.9 Nutritional deficiency, unspecified
0.000 0.631 0.369
E63.8 Other specified nutritional deficiencies
0.000 0.631 0.369
E63.1 Imbalance of constituents of food intake
0.000 0.631 0.369
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.631 0.369
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.631 0.369
E64.8 Sequelae of other nutritional deficiencies
0.000 0.631 0.369
E64.3 Sequelae of rickets
0.000 0.631 0.369
E64.2 Sequelae of vitamin C deficiency
0.000 0.631 0.369
E64.1 Sequelae of vitamin A deficiency
0.000 0.631 0.369
E64.0 Sequelae of protein-energy malnutrition
0.000 0.631 0.369
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.633 0.367
E29.9 Testicular dysfunction, unspecified
0.000 0.635 0.365
E29.8 Other testicular dysfunction
0.000 0.635 0.365
E29.0 Testicular hyperfunction
0.000 0.635 0.365
E13.8 With unspecified complications
0.001 0.638 0.362
E13.7 With multiple complications
0.001 0.638 0.362
E13.6 With other specified complications
0.001 0.638 0.362
E13.5 With peripheral circulatory complications
0.001 0.638 0.362
E13.4 With neurological complications
0.001 0.638 0.362
E13.3 With ophthalmic complications
0.001 0.638 0.362
E13.2 With renal complications
0.001 0.638 0.362
E13.1 With ketoacidosis
0.001 0.638 0.362
E13.0 With coma
0.001 0.638 0.362
E88 Other metabolic disorders
0.000 0.639 0.361
E23.7 Disorder of pituitary gland, unspecified
0.000 0.643 0.357
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.644 0.356
E26.9 Hyperaldosteronism, unspecified
0.000 0.648 0.352
E89.2 Postprocedural hypoparathyroidism
0.000 0.649 0.351
E55.0 Rickets, active
0.000 0.654 0.346
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.660 0.339
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.660 0.340
E73 Lactose intolerance
0.000 0.664 0.335
E23.6 Other disorders of pituitary gland
0.000 0.665 0.335
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.665 0.335
E23.1 Drug-induced hypopituitarism
0.000 0.665 0.335
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.676 0.324
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.676 0.324
E89.5 Postprocedural testicular hypofunction
0.000 0.676 0.324
E89.1 Postprocedural hypoinsulinaemia
0.000 0.676 0.324
E65-E68 Obesity and other hyperalimentation
0.000 0.679 0.321
E55.9 Vitamin D deficiency, unspecified
0.000 0.687 0.313
E14.9 Without complications
0.000 0.689 0.311
K90.9 Intestinal malabsorption, unspecified
0.000 0.692 0.308
E61.9 Deficiency of nutrient element, unspecified
0.000 0.695 0.305
E61.8 Deficiency of other specified nutrient elements
0.000 0.695 0.305
E61.7 Deficiency of multiple nutrient elements
0.000 0.695 0.305
E61.6 Vanadium deficiency
0.000 0.695 0.305
E61.5 Molybdenum deficiency
0.000 0.695 0.305
E61.4 Chromium deficiency
0.000 0.695 0.305
E61.3 Manganese deficiency
0.000 0.695 0.305
E61.0 Copper deficiency
0.000 0.695 0.305
E28.2 Polycystic ovarian syndrome
0.000 0.696 0.304
E83.3 Disorders of phosphorus metabolism
0.000 0.698 0.302
E61.2 Magnesium deficiency
0.000 0.704 0.295
E24.2 Drug-induced Cushing's syndrome
0.001 0.707 0.293
E00-E07 Disorders of thyroid gland
0.000 0.707 0.293
E85.3 Secondary systemic amyloidosis
0.000 0.708 0.292
E89.0 Postprocedural hypothyroidism
0.000 0.709 0.291
E89.4 Postprocedural ovarian failure
0.000 0.710 0.289
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.711 0.288
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.711 0.288
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.711 0.288
E70.3 Albinism
0.000 0.711 0.288
E70.2 Disorders of tyrosine metabolism
0.000 0.711 0.288
E70.1 Other hyperphenylalaninaemias
0.000 0.711 0.288
E70.0 Classical phenylketonuria
0.000 0.711 0.288
E71.3 Disorders of fatty-acid metabolism
0.000 0.711 0.288
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.711 0.288
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.711 0.288
E71.0 Maple-syrup-urine disease
0.000 0.711 0.288
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.711 0.288
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.711 0.288
E72.5 Disorders of glycine metabolism
0.000 0.711 0.288
E72.4 Disorders of ornithine metabolism
0.000 0.711 0.288
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.711 0.288
E72.2 Disorders of urea cycle metabolism
0.000 0.711 0.288
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.711 0.288
E72.0 Disorders of amino-acid transport
0.000 0.711 0.288
E75.6 Lipid storage disorder, unspecified
0.000 0.711 0.288
E75.5 Other lipid storage disorders
0.000 0.711 0.288
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.711 0.288
E75.3 Sphingolipidosis, unspecified
0.000 0.711 0.288
E75.2 Other sphingolipidosis
0.000 0.711 0.288
E75.1 Other gangliosidosis
0.000 0.711 0.288
E75.0 GM2 gangliosidosis
0.000 0.711 0.288
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.711 0.288
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.711 0.288
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.711 0.288
E76.2 Other mucopolysaccharidoses
0.000 0.711 0.288
E76.1 Mucopolysaccharidosis, type II
0.000 0.711 0.288
E76.0 Mucopolysaccharidosis, type I
0.000 0.711 0.288
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.711 0.288
E77.8 Other disorders of glycoprotein metabolism
0.000 0.711 0.288
E77.1 Defects in glycoprotein degradation
0.000 0.711 0.288
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.711 0.288
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.711 0.288
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.711 0.288
E79.1 Lesch-Nyhan syndrome
0.000 0.711 0.288
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.711 0.288
E84.9 Cystic fibrosis, unspecified
0.000 0.711 0.288
E84.8 Cystic fibrosis with other manifestations
0.000 0.711 0.288
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.711 0.288
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.711 0.288
E24.8 Other Cushing's syndrome
0.001 0.717 0.282
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.717 0.282
E24.3 Ectopic ACTH syndrome
0.001 0.717 0.282
E24.1 Nelson's syndrome
0.001 0.717 0.282
E85.8 Other amyloidosis
0.000 0.718 0.281
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.718 0.281
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.718 0.281
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.718 0.281
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.721 0.279
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.721 0.279
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.721 0.279
E74.2 Disorders of galactose metabolism
0.000 0.721 0.279
E74.1 Disorders of fructose metabolism
0.000 0.721 0.279
E74.0 Glycogen storage disease
0.000 0.721 0.279
E85.4 Organ-limited amyloidosis
0.000 0.724 0.275
E23.0 Hypopituitarism
0.000 0.725 0.275
K90.3 Pancreatic steatorrhoea
0.000 0.729 0.271
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.729 0.271
K90.1 Tropical sprue
0.000 0.729 0.271
E44.1 Mild protein-energy malnutrition
0.001 0.734 0.266
E44.0 Moderate protein-energy malnutrition
0.001 0.734 0.266
E85.9 Amyloidosis, unspecified
0.000 0.734 0.266
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.735 0.265
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.737 0.263
E80.5 Crigler-Najjar syndrome
0.000 0.737 0.263
E80.3 Defects of catalase and peroxydase
0.000 0.737 0.263
E80.2 Other porphyria
0.000 0.737 0.263
E80.1 Porphyria cutanea tarda
0.000 0.737 0.263
E80.0 Hereditary erythropoietic porphyria
0.000 0.737 0.263
E29.1 Testicular hypofunction
0.000 0.737 0.262
K90.8 Other intestinal malabsorption
0.000 0.739 0.261
E80.6 Other disorders of bilirubin metabolism
0.000 0.741 0.259
E88.9 Metabolic disorder, unspecified
0.000 0.741 0.259
E88.3 Tumour lysis syndrome
0.000 0.741 0.259
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.741 0.259
E06 Thyroiditis
0.000 0.743 0.257
E21.3 Hyperparathyroidism, unspecified
0.000 0.743 0.257
E21.2 Other hyperparathyroidism
0.000 0.744 0.255
E73.8 Other lactose intolerance
0.000 0.759 0.240
E73.1 Secondary lactase deficiency
0.000 0.759 0.240
E73.0 Congenital lactase deficiency
0.000 0.759 0.240
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.761 0.239
E23.2 Diabetes insipidus
0.000 0.764 0.235
E80.4 Gilbert's syndrome
0.000 0.767 0.233
E88.2 Lipomatosis, not elsewhere classified
0.000 0.767 0.233
E61.1 Iron deficiency
0.000 0.768 0.231
E67 Other hyperalimentation
0.000 0.769 0.230
E68 Sequelae of hyperalimentation
0.000 0.769 0.230
E21.4 Other specified disorders of parathyroid gland
0.000 0.776 0.224
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.779 0.221
E24.0 Pituitary-dependent Cushing's disease
0.001 0.784 0.215
E06.3 Autoimmune thyroiditis
0.000 0.785 0.215
E06.9 Thyroiditis, unspecified
0.000 0.787 0.213
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.790 0.210
E00 Congenital iodine-deficiency syndrome
0.000 0.790 0.210
E83.5 Disorders of calcium metabolism
0.000 0.793 0.207
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.796 0.203
E87.5 Hyperkalaemia
0.000 0.798 0.202
E21.0 Primary hyperparathyroidism
0.000 0.799 0.201
E88.8 Other specified metabolic disorders
0.000 0.799 0.200
E04 Other non-toxic goitre
0.000 0.800 0.200
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.805 0.194
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.808 0.192
E86 Volume depletion
0.000 0.812 0.188
E46 Unspecified protein-energy malnutrition
0.001 0.814 0.184
E06.5 Other chronic thyroiditis
0.000 0.815 0.184
E06.4 Drug-induced thyroiditis
0.000 0.815 0.184
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.815 0.184
E06.1 Subacute thyroiditis
0.000 0.815 0.184
E06.0 Acute thyroiditis
0.000 0.815 0.184
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.822 0.178
E73.9 Lactose intolerance, unspecified
0.000 0.826 0.174
E65 Localised adiposity
0.000 0.829 0.171
E24.9 Cushing's syndrome, unspecified
0.001 0.830 0.169
E67.8 Other specified hyperalimentation
0.000 0.834 0.165
E67.3 Hypervitaminosis D
0.000 0.834 0.165
E67.2 Megavitamin-B6 syndrome
0.000 0.834 0.165
E67.1 Hypercarotenaemia
0.000 0.834 0.165
E67.0 Hypervitaminosis A
0.000 0.834 0.165
E87.4 Mixed disorder of acid-base balance
0.000 0.841 0.159
E04.0 Non-toxic diffuse goitre
0.000 0.841 0.159
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.842 0.158
E13.9 Without complications
0.002 0.847 0.152
E04.1 Non-toxic single thyroid nodule
0.000 0.848 0.152
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.849 0.151
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.849 0.151
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.849 0.151
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.849 0.151
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.849 0.151
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.849 0.151
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.849 0.151
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.849 0.151
E07 Other disorders of thyroid
0.000 0.855 0.144
E04.8 Other specified non-toxic goitre
0.000 0.856 0.143
E87.3 Alkalosis
0.000 0.863 0.137
E04.2 Non-toxic multinodular goitre
0.000 0.868 0.132
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.869 0.131
E87.2 Acidosis
0.000 0.878 0.122
E87.0 Hyperosmolality and hypernatraemia
0.000 0.885 0.115
E04.9 Non-toxic goitre, unspecified
0.000 0.890 0.110
E07.1 Dyshormogenetic goitre
0.000 0.896 0.104
E07.0 Hypersecretion of calcitonin
0.000 0.896 0.104
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.899 0.101
K90-K93 Other diseases of the digestive system
0.000 0.900 0.100
E05.5 Thyroid crisis or storm
0.000 0.906 0.094
E05.4 Thyrotoxicosis factitia
0.000 0.906 0.094
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.906 0.094
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.906 0.094
E07.8 Other specified disorders of thyroid
0.000 0.908 0.092
E03 Other hypothyroidism
0.000 0.914 0.086
E05.8 Other thyrotoxicosis
0.000 0.914 0.085
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.917 0.083
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.920 0.080
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.927 0.073
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.928 0.072
K91.4 Colostomy and enterostomy malfunction
0.000 0.930 0.070
E87.7 Fluid overload
0.000 0.935 0.065
E03.5 Myxoedema coma
0.000 0.938 0.062
E03.4 Atrophy of thyroid (acquired)
0.000 0.938 0.062
E03.3 Postinfectious hypothyroidism
0.000 0.938 0.062
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.938 0.062
E03.1 Congenital hypothyroidism without goitre
0.000 0.938 0.062
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.938 0.062
E07.9 Disorder of thyroid, unspecified
0.000 0.939 0.061
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.942 0.058
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.943 0.057
K91.5 Postcholecystectomy syndrome
0.000 0.943 0.057
K91.1 Postgastric surgery syndromes
0.000 0.944 0.055
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.948 0.051
K93.1 Megacolon in Chagas' disease
0.000 0.948 0.051
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.948 0.051
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.950 0.050
E05.9 Thyrotoxicosis, unspecified
0.000 0.956 0.044
K91.3 Postoperative intestinal obstruction
0.000 0.956 0.043
E03.8 Other specified hypothyroidism
0.000 0.957 0.043
E87.6 Hypokalaemia
0.000 0.958 0.042
E78.4 Other hyperlipidaemia
0.000 0.960 0.040
E78.1 Pure hyperglyceridaemia
0.000 0.962 0.038
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.962 0.038
E78.6 Lipoprotein deficiency
0.000 0.964 0.036
E78.3 Hyperchylomicronaemia
0.000 0.964 0.036
E66 Obesity
0.000 0.965 0.035
E78.8 Other disorders of lipoprotein metabolism
0.000 0.974 0.025
E66.1 Drug-induced obesity
0.000 0.974 0.025
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.977 0.022
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.979 0.021
K92 Other diseases of digestive system
0.000 0.980 0.020
E78.2 Mixed hyperlipidaemia
0.000 0.980 0.019
E66.0 Obesity due to excess calories
0.000 0.982 0.018
K92.8 Other specified diseases of digestive system
0.000 0.982 0.018
G62.9 Polyneuropathy, unspecified
0.000 0.984 0.016
K92.9 Disease of digestive system, unspecified
0.000 0.985 0.014
M31.3 Wegener's granulomatosis
0.013 0.987 0.000
G62 Other polyneuropathies
0.000 0.987 0.013
J98.1 Pulmonary collapse
0.012 0.988 0.000
M31.6 Other giant cell arteritis
0.012 0.988 0.000
G63.2 Diabetic polyneuropathy
0.000 0.988 0.012
G62.0 Drug-induced polyneuropathy
0.000 0.988 0.012
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.989 0.011
M31 Other necrotising vasculopathies
0.011 0.989 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.989 0.011
E11.9 Without complications
0.000 0.990 0.010
G62.2 Polyneuropathy due to other toxic agents
0.000 0.990 0.009
E66.8 Other obesity
0.000 0.991 0.009
G61 Inflammatory polyneuropathy
0.000 0.992 0.008
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.000 0.992 0.008
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.992 0.008
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.992 0.008
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.992 0.008
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.992 0.008
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.992 0.008
G63.1 Polyneuropathy in neoplastic disease
0.000 0.992 0.008
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.992 0.008
M31.9 Necrotising vasculopathy, unspecified
0.008 0.992 0.000
M31.8 Other specified necrotising vasculopathies
0.008 0.992 0.000
M31.7 Microscopic polyangiitis
0.008 0.992 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.008 0.992 0.000
M31.2 Lethal midline granuloma
0.008 0.992 0.000
M31.1 Thrombotic microangiopathy
0.008 0.992 0.000
M31.0 Hypersensitivity angiitis
0.008 0.992 0.000
G62.1 Alcoholic polyneuropathy
0.000 0.992 0.008
G64 Other disorders of peripheral nervous system
0.000 0.992 0.008
G60 Hereditary and idiopathic neuropathy
0.000 0.992 0.008
G56.0 Carpal tunnel syndrome
0.000 0.993 0.007
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.007 0.993 0.000
G61.0 Guillain-Barre syndrome
0.000 0.993 0.007
G60.8 Other hereditary and idiopathic neuropathies
0.000 0.993 0.007
K92.0 Haematemesis
0.000 0.993 0.007
G62.8 Other specified polyneuropathies
0.000 0.993 0.007
G61.1 Serum neuropathy
0.000 0.994 0.006
G61.8 Other inflammatory polyneuropathies
0.000 0.994 0.006
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.006 0.994 0.000
M65.34 Trigger finger-Hand
0.000 0.994 0.006
Z87.8 Personal history of other specified conditions
0.000 0.994 0.006
G61.9 Inflammatory polyneuropathy, unspecified
0.000 0.994 0.006
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.000 0.994 0.006
G60.3 Idiopathic progressive neuropathy
0.000 0.994 0.006
G60.2 Neuropathy in association with hereditary ataxia
0.000 0.994 0.006
G60.1 Refsum's disease
0.000 0.994 0.006
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.994 0.006
H36.0 Diabetic retinopathy
0.000 0.994 0.006
I35.0 Aortic (valve) stenosis
0.005 0.995 0.000
G80.9 Infantile cerebral palsy, unspecified
0.005 0.995 0.000
M20.5 Other deformities of toe(s) (acquired)
0.005 0.995 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.000 0.995 0.005
W19.9 Unspecified place
0.000 0.996 0.004
L29.9 Pruritus, unspecified
0.000 0.996 0.004
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.004 0.996 0.000
J98 Other respiratory disorders
0.004 0.996 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.996 0.004
J98.5 Diseases of mediastinum, not elsewhere classified
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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