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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129093
log Bayes Factor = 96.7139
Chromosome 6   position 29,170,261  (GRCh37) Explore rs3129093 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
E16 Other disorders of pancreatic internal secretion
0.997 0.003 0.000
E16.2 Hypoglycaemia, unspecified
0.993 0.007 0.000
E03 Other hypothyroidism
0.985 0.015 0.000
E10.2 With renal complications
0.976 0.024 0.000
E03.9 Hypothyroidism, unspecified
0.972 0.028 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.972 0.028 0.000
N40 Hyperplasia of prostate
0.000 0.080 0.920
E40-E46 Malnutrition
0.900 0.100 0.000
E10.4 With neurological complications
0.876 0.124 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.875 0.125 0.000
E10.1 With ketoacidosis
0.872 0.128 0.000
E14 Unspecified diabetes mellitus
0.840 0.160 0.000
E16.1 Other hypoglycaemia
0.834 0.166 0.000
E46 Unspecified protein-energy malnutrition
0.829 0.171 0.000
E13 Other specified diabetes mellitus
0.818 0.182 0.000
E10.7 With multiple complications
0.790 0.210 0.000
E10.0 With coma
0.777 0.223 0.000
E10.6 With other specified complications
0.762 0.238 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.247 0.753
E14.3 With ophthalmic complications
0.751 0.249 0.000
E10.5 With peripheral circulatory complications
0.747 0.253 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.727 0.273 0.000
E03.8 Other specified hypothyroidism
0.726 0.274 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.715 0.285 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.715 0.285 0.000
E16.4 Abnormal secretion of gastrin
0.715 0.285 0.000
E16.3 Increased secretion of glucagon
0.715 0.285 0.000
E03.5 Myxoedema coma
0.706 0.294 0.000
E03.4 Atrophy of thyroid (acquired)
0.706 0.294 0.000
E03.3 Postinfectious hypothyroidism
0.706 0.294 0.000
E03.1 Congenital hypothyroidism without goitre
0.706 0.294 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.702 0.297 0.000
E14.1 With ketoacidosis
0.689 0.311 0.000
E13.9 Without complications
0.668 0.332 0.000
E05.8 Other thyrotoxicosis
0.663 0.336 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.656 0.344 0.000
E14.6 With other specified complications
0.646 0.353 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.646 0.354 0.000
E45 Retarded development following protein-energy malnutrition
0.646 0.354 0.000
E43 Unspecified severe protein-energy malnutrition
0.646 0.354 0.000
E42 Marasmic kwashiorkor
0.646 0.354 0.000
E41 Nutritional marasmus
0.646 0.354 0.000
E40 Kwashiorkor
0.646 0.354 0.000
E07 Other disorders of thyroid
0.630 0.369 0.000
E14.4 With neurological complications
0.628 0.372 0.000
N40-N51 Diseases of male genital organs
0.000 0.374 0.626
E10.8 With unspecified complications
0.624 0.376 0.000
E50-E64 Other nutritional deficiencies
0.621 0.379 0.000
E13.3 With ophthalmic complications
0.618 0.382 0.000
E14.8 With unspecified complications
0.614 0.385 0.000
E14.2 Withrenal complications
0.611 0.389 0.000
N42 Other disorders of prostate
0.000 0.390 0.610
E14.7 With multiple complications
0.602 0.398 0.000
E14.0 With coma
0.602 0.398 0.000
N41 Inflammatory diseases of prostate
0.000 0.402 0.598
E06 Thyroiditis
0.588 0.411 0.000
E14.5 With peripheral circulatory complications
0.588 0.412 0.000
E13.8 With unspecified complications
0.587 0.413 0.000
E13.7 With multiple complications
0.587 0.413 0.000
E13.6 With other specified complications
0.587 0.413 0.000
E13.5 With peripheral circulatory complications
0.587 0.413 0.000
E13.4 With neurological complications
0.587 0.413 0.000
E13.2 With renal complications
0.587 0.413 0.000
E13.1 With ketoacidosis
0.587 0.413 0.000
E13.0 With coma
0.587 0.413 0.000
E11 Non-insulin-dependent diabetes mellitus
0.586 0.414 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.414 0.586
N42.1 Congestion and haemorrhage of prostate
0.000 0.416 0.584
N42.8 Other specified disorders of prostate
0.000 0.418 0.582
E11.5 With peripheral circulatory complications
0.568 0.432 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.562 0.437 0.000
Z46.6 Fitting and adjustment of urinary device
0.000 0.444 0.556
K90 Intestinal malabsorption
0.534 0.466 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
N46 Male infertility
0.000 0.489 0.511
E07.8 Other specified disorders of thyroid
0.491 0.509 0.000
K40 Inguinal hernia
0.000 0.511 0.489
E11.3 With ophthalmic complications
0.474 0.526 0.000
N44 Torsion of testis
0.000 0.530 0.470
E44.1 Mild protein-energy malnutrition
0.463 0.537 0.000
E44.0 Moderate protein-energy malnutrition
0.463 0.537 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.537 0.463
E58 Dietary calcium deficiency
0.459 0.541 0.000
N41.0 Acute prostatitis
0.000 0.541 0.459
E56 Other vitamin deficiencies
0.456 0.544 0.000
E55 Vitamin D deficiency
0.453 0.547 0.000
E07.1 Dyshormogenetic goitre
0.452 0.548 0.000
E07.0 Hypersecretion of calcitonin
0.452 0.548 0.000
E51 Thiamine deficiency
0.449 0.551 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.551 0.449
E64 Sequelae of malnutrition and other nutritional deficiencies
0.445 0.555 0.000
E63 Other nutritional deficiencies
0.445 0.555 0.000
E50 Vitamin A deficiency
0.445 0.555 0.000
E60 Dietary zinc deficiency
0.445 0.555 0.000
E59 Dietary selenium deficiency
0.445 0.555 0.000
E54 Ascorbic acid deficiency
0.445 0.555 0.000
E52 Niacin deficiency [pellagra]
0.445 0.555 0.000
E06.9 Thyroiditis, unspecified
0.443 0.557 0.000
N42.3 Dysplasia of prostate
0.000 0.563 0.437
E06.5 Other chronic thyroiditis
0.435 0.565 0.000
N42.2 Atrophy of prostate
0.000 0.565 0.435
N42.0 Calculus of prostate
0.000 0.567 0.433
K90.8 Other intestinal malabsorption
0.433 0.567 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.569 0.431
N41.3 Prostatocystitis
0.000 0.571 0.429
N41.2 Abscess of prostate
0.000 0.571 0.429
E06.4 Drug-induced thyroiditis
0.422 0.578 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.422 0.578 0.000
E06.1 Subacute thyroiditis
0.422 0.578 0.000
E06.0 Acute thyroiditis
0.422 0.578 0.000
E11.0 With coma
0.421 0.579 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.579 0.421
E11.7 With multiple complications
0.420 0.580 0.000
T39.1 4-Aminophenol derivatives
0.000 0.580 0.420
N41.8 Other inflammatory diseases of prostate
0.000 0.584 0.416
T42.4 Benzodiazepines
0.000 0.590 0.410
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.409 0.590 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.593 0.407
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.594 0.406
E11.6 With other specified complications
0.394 0.606 0.000
E11.1 With ketoacidosis
0.392 0.608 0.000
T39.0 Salicylates
0.000 0.609 0.391
E61 Deficiency of other nutrient elements
0.390 0.609 0.000
K90.3 Pancreatic steatorrhoea
0.383 0.617 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.383 0.617 0.000
K90.1 Tropical sprue
0.383 0.617 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.626 0.374
E53 Deficiency of other B group vitamins
0.363 0.637 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.638 0.362
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.639 0.361
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.642 0.358
E11.8 With unspecified complications
0.356 0.644 0.000
E65-E68 Obesity and other hyperalimentation
0.352 0.647 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.647 0.353
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.649 0.351
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.649 0.351
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.649 0.351
K90.9 Intestinal malabsorption, unspecified
0.349 0.651 0.000
E56.1 Deficiency of vitamin K
0.338 0.662 0.000
E55.9 Vitamin D deficiency, unspecified
0.333 0.667 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.668 0.332
E11.2 With renal complications
0.328 0.672 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.673 0.327
E56.9 Vitamin deficiency, unspecified
0.327 0.673 0.000
E56.8 Deficiency of other vitamins
0.327 0.673 0.000
E56.0 Deficiency of vitamin E
0.327 0.673 0.000
E51.2 Wernicke's encephalopathy
0.326 0.674 0.000
E55.0 Rickets, active
0.325 0.675 0.000
E51.9 Thiamine deficiency, unspecified
0.322 0.678 0.000
E51.8 Other manifestations of thiamine deficiency
0.322 0.678 0.000
E51.1 Beriberi
0.322 0.678 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.678 0.322
N51.2 Balanitis in diseases classified elsewhere
0.000 0.678 0.322
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.678 0.322
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.678 0.322
N49.2 Inflammatory disorders of scrotum
0.000 0.680 0.320
E50.9 Vitamin A deficiency, unspecified
0.319 0.681 0.000
E50.8 Other manifestations of vitamin A deficiency
0.319 0.681 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.319 0.681 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.319 0.681 0.000
E50.5 Vitamin A deficiency with night blindness
0.319 0.681 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.319 0.681 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.319 0.681 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.319 0.681 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.319 0.681 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.319 0.681 0.000
E63.9 Nutritional deficiency, unspecified
0.319 0.681 0.000
E63.8 Other specified nutritional deficiencies
0.319 0.681 0.000
E63.1 Imbalance of constituents of food intake
0.319 0.681 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.319 0.681 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.319 0.681 0.000
E64.8 Sequelae of other nutritional deficiencies
0.319 0.681 0.000
E64.3 Sequelae of rickets
0.319 0.681 0.000
E64.2 Sequelae of vitamin C deficiency
0.319 0.681 0.000
E64.1 Sequelae of vitamin A deficiency
0.319 0.681 0.000
E64.0 Sequelae of protein-energy malnutrition
0.319 0.681 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.682 0.318
T36 Poisoning by systemic antibiotics
0.000 0.686 0.314
N45 Orchitis and epididymitis
0.000 0.691 0.309
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.691 0.309
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.691 0.309
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.691 0.309
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.692 0.308
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.693 0.307
T39.4 Antirheumatics, not elsewhere classified
0.000 0.698 0.302
T39.2 Pyrazolone derivatives
0.000 0.698 0.302
N41.1 Chronic prostatitis
0.000 0.707 0.293
E07.9 Disorder of thyroid, unspecified
0.293 0.707 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.708 0.292
T42.3 Barbiturates
0.000 0.708 0.292
T42.2 Succinimides and oxazolidinediones
0.000 0.708 0.292
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.709 0.291
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.709 0.291
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.709 0.291
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.709 0.291
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.715 0.285
E61.9 Deficiency of nutrient element, unspecified
0.280 0.720 0.000
E61.8 Deficiency of other specified nutrient elements
0.280 0.720 0.000
E61.7 Deficiency of multiple nutrient elements
0.280 0.720 0.000
E61.6 Vanadium deficiency
0.280 0.720 0.000
E61.5 Molybdenum deficiency
0.280 0.720 0.000
E61.4 Chromium deficiency
0.280 0.720 0.000
E61.3 Manganese deficiency
0.280 0.720 0.000
E61.0 Copper deficiency
0.280 0.720 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.721 0.279
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.722 0.277
T42.0 Hydantoin derivatives
0.000 0.728 0.272
E61.1 Iron deficiency
0.270 0.730 0.000
T42.1 Iminostilbenes
0.000 0.733 0.267
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.738 0.262
T43.2 Other and unspecified antidepressants
0.000 0.739 0.261
E53.1 Pyridoxine deficiency
0.260 0.739 0.000
E53.0 Riboflavin deficiency
0.260 0.739 0.000
T50.8 Diagnostic agents
0.000 0.741 0.259
T50.7 Analeptics and opioid receptor antagonists
0.000 0.741 0.259
T50.5 Appetite depressants
0.000 0.741 0.259
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.741 0.259
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.741 0.259
T50.1 Loop [high-ceiling] diuretics
0.000 0.741 0.259
T50.0 Mineralocorticoids and their antagonists
0.000 0.741 0.259
T50.4 Drugs affecting uric acid metabolism
0.000 0.743 0.256
T43.6 Psychostimulants with abuse potential
0.000 0.745 0.255
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.746 0.254
E67 Other hyperalimentation
0.253 0.747 0.000
E68 Sequelae of hyperalimentation
0.253 0.747 0.000
T43.9 Psychotropic drug, unspecified
0.000 0.747 0.253
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.747 0.253
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.747 0.253
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.751 0.249
T36.0 Penicillins
0.000 0.752 0.248
N50 Other disorders of male genital organs
0.000 0.755 0.245
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.758 0.242
E61.2 Magnesium deficiency
0.240 0.760 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.764 0.236
K75.4 Autoimmune hepatitis
0.233 0.767 0.000
T45.2 Vitamins, not elsewhere classified
0.000 0.768 0.232
E53.9 Vitamin B deficiency, unspecified
0.230 0.770 0.000
T36.9 Systemic antibiotic, unspecified
0.000 0.775 0.225
T36.8 Other systemic antibiotics
0.000 0.775 0.225
T36.7 Antifungal antibiotics, systemically used
0.000 0.775 0.225
T36.6 Rifamycins
0.000 0.775 0.225
T36.5 Aminoglycosides
0.000 0.775 0.225
T36.4 Tetracyclines
0.000 0.775 0.225
T36.3 Macrolides
0.000 0.775 0.225
T36.2 Chloramphenicol group
0.000 0.775 0.225
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.775 0.225
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.775 0.225
T45.5 Anticoagulants
0.000 0.776 0.224
E06.3 Autoimmune thyroiditis
0.223 0.777 0.000
E53.8 Deficiency of other specified B group vitamins
0.221 0.779 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.780 0.220
T45.8 Other primarily systemic and haematological agents
0.000 0.780 0.220
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.780 0.220
T45.6 Fibrinolysis-affecting drugs
0.000 0.780 0.220
T45.4 Iron and its compounds
0.000 0.780 0.220
T45.3 Enzymes, not elsewhere classified
0.000 0.780 0.220
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.783 0.217
K75 Other inflammatory liver diseases
0.217 0.783 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.788 0.212
N43 Hydrocele and spermatocele
0.000 0.789 0.211
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.791 0.209
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.791 0.209
T37.5 Antiviral drugs
0.000 0.791 0.209
T37.4 Anthelminthics
0.000 0.791 0.209
T37.3 Other antiprotozoal drugs
0.000 0.791 0.209
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.791 0.209
T37.1 Antimycobacterial drugs
0.000 0.791 0.209
T37.0 Sulphonamides
0.000 0.791 0.209
T41.5 Therapeutic gases
0.000 0.791 0.209
T41.4 Anaesthetic, unspecified
0.000 0.791 0.209
T41.3 Local anaesthetics
0.000 0.791 0.209
T41.2 Other and unspecified general anaesthetics
0.000 0.791 0.209
T41.1 Intravenous anaesthetics
0.000 0.791 0.209
T41.0 Inhaled anaesthetics
0.000 0.791 0.209
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.791 0.209
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.791 0.209
T48.5 Anti-common-cold drugs
0.000 0.791 0.209
T48.4 Expectorants
0.000 0.791 0.209
T48.3 Antitussives
0.000 0.791 0.209
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.791 0.209
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.791 0.209
T48.0 Oxytocic drugs
0.000 0.791 0.209
T49.9 Topical agent, unspecified
0.000 0.791 0.209
T49.8 Other topical agents
0.000 0.791 0.209
T49.7 Dental drugs, topically applied
0.000 0.791 0.209
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.791 0.209
T49.5 Ophthalmological drugs and preparations
0.000 0.791 0.209
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.791 0.209
T49.3 Emollients, demulcents and protectants
0.000 0.791 0.209
T49.2 Local astringents and local detergents
0.000 0.791 0.209
T49.1 Antipruritics
0.000 0.791 0.209
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.791 0.209
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.795 0.204
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.795 0.204
T47.7 Emetics
0.000 0.795 0.204
T47.6 Antidiarrhoeal drugs
0.000 0.795 0.204
T47.5 Digestants
0.000 0.795 0.204
T47.3 Saline and osmotic laxatives
0.000 0.795 0.204
T47.2 Stimulant laxatives
0.000 0.795 0.204
T47.0 Histamine H(2)-receptor antagonists
0.000 0.795 0.204
T45.0 Antiallergic and antiemetic drugs
0.000 0.798 0.202
N50.9 Disorder of male genital organs, unspecified
0.000 0.798 0.202
K75.9 Inflammatory liver disease, unspecified
0.197 0.803 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.804 0.196
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.806 0.194
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.810 0.190
T47.4 Other laxatives
0.000 0.811 0.189
E67.8 Other specified hyperalimentation
0.181 0.818 0.000
E67.3 Hypervitaminosis D
0.181 0.818 0.000
E67.2 Megavitamin-B6 syndrome
0.181 0.818 0.000
E67.1 Hypercarotenaemia
0.181 0.818 0.000
E67.0 Hypervitaminosis A
0.181 0.818 0.000
K75.8 Other specified inflammatory liver diseases
0.180 0.820 0.000
E65 Localised adiposity
0.178 0.821 0.000
E20-E35 Disorders of other endocrine glands
0.176 0.824 0.000
T38.1 Thyroid hormones and substitutes
0.000 0.825 0.175
T38.9 Other and unspecified hormone antagonists
0.000 0.826 0.173
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.826 0.173
T38.7 Androgens and anabolic congeners
0.000 0.826 0.173
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.826 0.173
T38.5 Other oestrogens and progestogens
0.000 0.826 0.173
T38.4 Oral contraceptives
0.000 0.826 0.173
T38.2 Antithyroid drugs
0.000 0.826 0.173
T38.0 Glucocorticoids and synthetic analogues
0.000 0.826 0.173
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.828 0.171
N48 Other disorders of penis
0.000 0.832 0.168
K75.0 Abscess of liver
0.165 0.835 0.000
K70-K77 Diseases of liver
0.162 0.838 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.839 0.161
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.839 0.161
T46.7 Peripheral vasodilators
0.000 0.839 0.161
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.839 0.161
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.839 0.161
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.839 0.161
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.839 0.161
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.841 0.159
N50.0 Atrophy of testis
0.000 0.843 0.157
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.844 0.156
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.844 0.156
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.844 0.156
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.844 0.156
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.844 0.156
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.844 0.156
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.844 0.156
T44.0 Anticholinesterase agents
0.000 0.844 0.156
K75.2 Nonspecific reactive hepatitis
0.155 0.844 0.000
K75.1 Phlebitis of portal vein
0.155 0.844 0.000
K72 Hepatic failure, not elsewhere classified
0.153 0.847 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.847 0.152
N43.1 Infected hydrocele
0.000 0.848 0.152
N43.0 Encysted hydrocele
0.000 0.848 0.152
N48.1 Balanoposthitis
0.000 0.849 0.151
N43.2 Other hydrocele
0.000 0.852 0.147
K73 Chronic hepatitis, not elsewhere classified
0.147 0.853 0.000
N50.1 Vascular disorders of male genital organs
0.000 0.854 0.146
E27 Other disorders of adrenal gland
0.145 0.855 0.000
E24 Cushing's syndrome
0.145 0.855 0.000
T40.2 Other opioids
0.000 0.856 0.144
E27.1 Primary adrenocortical insufficiency
0.143 0.857 0.000
N20.0 Calculus of kidney
0.000 0.857 0.143
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.001 0.857 0.142
E14.9 Without complications
0.142 0.858 0.000
E04 Other non-toxic goitre
0.142 0.858 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.860 0.139
T40.8 Lysergide [LSD]
0.000 0.860 0.139
T40.7 Cannabis (derivatives)
0.000 0.860 0.139
T40.5 Cocaine
0.000 0.860 0.139
T40.3 Methadone
0.000 0.860 0.139
T40.1 Heroin
0.000 0.860 0.139
T40.0 Opium
0.000 0.860 0.139
K75.3 Granulomatous hepatitis, not elsewhere classified
0.139 0.861 0.000
E11.4 With neurological complications
0.137 0.863 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.863 0.137
K72.9 Hepatic failure, unspecified
0.135 0.865 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.865 0.134
K72.0 Acute and subacute hepatic failure
0.134 0.866 0.000
K73.9 Chronic hepatitis, unspecified
0.132 0.868 0.000
E83 Disorders of mineral metabolism
0.021 0.870 0.109
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.871 0.129
N48.2 Other inflammatory disorders of penis
0.000 0.871 0.129
N43.4 Spermatocele
0.000 0.873 0.126
E35 Disorders of endocrine glands in diseases classified elsewhere
0.126 0.873 0.000
E32 Diseases of thymus
0.126 0.873 0.000
E31 Polyglandular dysfunction
0.126 0.873 0.000
E30 Disorders of puberty, not elsewhere classified
0.126 0.873 0.000
T40.6 Other and unspecified narcotics
0.000 0.874 0.126
E20 Hypoparathyroidism
0.126 0.874 0.000
E25 Adrenogenital disorders
0.126 0.874 0.000
E28 Ovarian dysfunction
0.124 0.876 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.877 0.122
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.879 0.120
K73.2 Chronic active hepatitis, not elsewhere classified
0.120 0.880 0.000
E24.2 Drug-induced Cushing's syndrome
0.119 0.880 0.000
K71 Toxic liver disease
0.119 0.881 0.000
K72.1 Chronic hepatic failure
0.118 0.882 0.000
K77 Liver disorders in diseases classified elsewhere
0.116 0.884 0.000
K70 Alcoholic liver disease
0.116 0.884 0.000
N48.4 Impotence of organic origin
0.000 0.884 0.116
E24.0 Pituitary-dependent Cushing's disease
0.116 0.884 0.000
E26 Hyperaldosteronism
0.115 0.885 0.000
T46.1 Calcium-channel blockers
0.000 0.886 0.114
K74 Fibrosis and cirrhosis of liver
0.108 0.892 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.106 0.894 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.106 0.894 0.000
N48.5 Ulcer of penis
0.000 0.895 0.105
K73.8 Other chronic hepatitis, not elsewhere classified
0.105 0.895 0.000
N48.3 Priapism
0.000 0.895 0.105
E27.5 Adrenomedullary hyperfunction
0.104 0.896 0.000
E27.0 Other adrenocortical overactivity
0.104 0.896 0.000
E24.8 Other Cushing's syndrome
0.104 0.896 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.104 0.896 0.000
E24.3 Ectopic ACTH syndrome
0.104 0.896 0.000
E24.1 Nelson's syndrome
0.104 0.896 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.104 0.896 0.000
E04.8 Other specified non-toxic goitre
0.102 0.898 0.000
N48.9 Disorder of penis, unspecified
0.000 0.899 0.101
E11.9 Without complications
0.101 0.899 0.000
N48.0 Leukoplakia of penis
0.000 0.900 0.100
E70-E90 Metabolic disorders
0.099 0.900 0.001
E27.3 Drug-induced adrenocortical insufficiency
0.098 0.902 0.000
K70.1 Alcoholic hepatitis
0.097 0.903 0.000
E04.0 Non-toxic diffuse goitre
0.097 0.903 0.000
M20.1 Hallux valgus (acquired)
0.000 0.903 0.097
E24.9 Cushing's syndrome, unspecified
0.095 0.905 0.000
K70.4 Alcoholic hepatic failure
0.095 0.905 0.000
E34 Other endocrine disorders
0.094 0.905 0.000
E28.2 Polycystic ovarian syndrome
0.094 0.906 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.015 0.906 0.078
E83.8 Other disorders of mineral metabolism
0.015 0.906 0.078
E83.2 Disorders of zinc metabolism
0.015 0.906 0.078
E83.0 Disorders of copper metabolism
0.015 0.906 0.078
E29 Testicular dysfunction
0.092 0.907 0.000
E30.9 Disorder of puberty, unspecified
0.091 0.909 0.000
E30.8 Other disorders of puberty
0.091 0.909 0.000
E30.1 Precocious puberty
0.091 0.909 0.000
E30.0 Delayed puberty
0.091 0.909 0.000
E31.9 Polyglandular dysfunction, unspecified
0.091 0.909 0.000
E31.8 Other polyglandular dysfunction
0.091 0.909 0.000
E31.1 Polyglandular hyperfunction
0.091 0.909 0.000
E31.0 Autoimmune polyglandular failure
0.091 0.909 0.000
E32.9 Disease of thymus, unspecified
0.091 0.909 0.000
E32.8 Other diseases of thymus
0.091 0.909 0.000
E32.1 Abscess of thymus
0.091 0.909 0.000
E32.0 Persistent hyperplasia of thymus
0.091 0.909 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.091 0.909 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.091 0.909 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.091 0.909 0.000
K74.0 Hepatic fibrosis
0.091 0.909 0.000
E20.8 Other hypoparathyroidism
0.091 0.909 0.000
E20.1 Pseudohypoparathyroidism
0.091 0.909 0.000
E20.0 Idiopathic hypoparathyroidism
0.091 0.909 0.000
E25.9 Adrenogenital disorder, unspecified
0.090 0.909 0.000
E25.8 Other adrenogenital disorders
0.090 0.909 0.000
E20.9 Hypoparathyroidism, unspecified
0.090 0.910 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.090 0.910 0.000
K70.0 Alcoholic fatty liver
0.089 0.911 0.000
E28.9 Ovarian dysfunction, unspecified
0.089 0.911 0.000
E28.8 Other ovarian dysfunction
0.089 0.911 0.000
E28.1 Androgen excess
0.089 0.911 0.000
E28.0 Oestrogen excess
0.089 0.911 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.088 0.912 0.000
K71.0 Toxic liver disease with cholestasis
0.088 0.912 0.000
E83.3 Disorders of phosphorus metabolism
0.010 0.913 0.078

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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