TreeWAS – Variant ID: rs3129269

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.020	0.980
M06.9 Rheumatoid arthritis, unspecified	0.000	0.144	0.856
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.151	0.849
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.195	0.805
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.197	0.803
K90.0 Coeliac disease	0.000	0.220	0.780
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.230	0.770
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.258	0.742
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.266	0.734
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.295	0.705
E03 Other hypothyroidism	0.000	0.296	0.704
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.296	0.704
E03.8 Other specified hypothyroidism	0.000	0.386	0.614
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.404	0.596
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.416	0.584
E03.1 Congenital hypothyroidism without goitre	0.000	0.460	0.540
M06 Other rheumatoid arthritis	0.000	0.466	0.534
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.483	0.517
E03.5 Myxoedema coma	0.000	0.495	0.505
E03.4 Atrophy of thyroid (acquired)	0.000	0.495	0.505
E03.3 Postinfectious hypothyroidism	0.000	0.495	0.505
K90 Intestinal malabsorption	0.000	0.518	0.482
M06.3 Rheumatoid nodule	0.000	0.524	0.476
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.529	0.470
M06.4 Inflammatory polyarthropathy	0.000	0.557	0.442
M06.34 Rheumatoid nodule (Hand)	0.000	0.568	0.432
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.578	0.422
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.607	0.393
M06.2 Rheumatoid bursitis	0.000	0.617	0.383
M06.1 Adult-onset Still's disease	0.000	0.617	0.383
M06.8 Other specified rheumatoid arthritis	0.000	0.632	0.368
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.640	0.359
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.648	0.352
K90.3 Pancreatic steatorrhoea	0.000	0.654	0.345
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.654	0.345
K90.1 Tropical sprue	0.000	0.654	0.345
K90.9 Intestinal malabsorption, unspecified	0.000	0.657	0.343
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.659	0.341
M06.38 Rheumatoid nodule (Other)	0.000	0.659	0.341
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.659	0.341
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.659	0.341
M06.33 Rheumatoid nodule (Forearm)	0.000	0.659	0.341
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.659	0.341
K90.8 Other intestinal malabsorption	0.000	0.680	0.320
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.683	0.317
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.683	0.317
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.683	0.317
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.683	0.317
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.683	0.317
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.683	0.317
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.683	0.317
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.684	0.316
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.698	0.302
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.704	0.296
M06.0 Seronegative rheumatoid arthritis	0.000	0.725	0.275
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.725	0.275
M06.18 Adult-onset Still's disease (Other)	0.000	0.725	0.275
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.725	0.275
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.725	0.275
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.725	0.275
M06.14 Adult-onset Still's disease (Hand)	0.000	0.725	0.275
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.725	0.275
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.725	0.275
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.725	0.275
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.725	0.275
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.725	0.275
M06.28 Rheumatoid bursitis (Other)	0.000	0.725	0.275
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.725	0.275
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.725	0.275
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.725	0.275
M06.24 Rheumatoid bursitis (Hand)	0.000	0.725	0.275
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.725	0.275
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.725	0.275
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.725	0.275
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.725	0.275
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.736	0.264
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.736	0.264
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.736	0.264
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.736	0.264
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.736	0.264
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.736	0.264
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.736	0.264
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.736	0.264
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.736	0.264
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.751	0.248
E00-E07 Disorders of thyroid gland	0.000	0.775	0.225
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.787	0.212
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.788	0.212
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.794	0.206
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.803	0.197
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.803	0.197
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.803	0.197
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.803	0.197
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.803	0.197
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.811	0.189
E07 Other disorders of thyroid	0.000	0.813	0.187
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.822	0.178
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.829	0.170
E05.9 Thyrotoxicosis, unspecified	0.000	0.834	0.166
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.838	0.161
E00 Congenital iodine-deficiency syndrome	0.000	0.838	0.161
E07.9 Disorder of thyroid, unspecified	0.000	0.843	0.157
E05.5 Thyroid crisis or storm	0.000	0.847	0.152
E05.4 Thyrotoxicosis factitia	0.000	0.847	0.152
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.847	0.152
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.847	0.152
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.849	0.151
E05.8 Other thyrotoxicosis	0.000	0.857	0.142
E07.8 Other specified disorders of thyroid	0.000	0.861	0.138
E07.1 Dyshormogenetic goitre	0.000	0.866	0.134
E07.0 Hypersecretion of calcitonin	0.000	0.866	0.134
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.867	0.133
E02 Subclinical iodine-deficiency hypothyroidism	0.001	0.875	0.125
J47 Bronchiectasis	0.000	0.881	0.119
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.884	0.116
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.884	0.116
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.884	0.116
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.884	0.116
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.884	0.116
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.884	0.116
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.884	0.116
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.884	0.116
K90-K93 Other diseases of the digestive system	0.000	0.924	0.076
E06 Thyroiditis	0.001	0.926	0.073
K91.4 Colostomy and enterostomy malfunction	0.000	0.943	0.057
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.945	0.054
E06.4 Drug-induced thyroiditis	0.001	0.947	0.052
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.947	0.052
E06.0 Acute thyroiditis	0.001	0.947	0.052
E06.5 Other chronic thyroiditis	0.001	0.949	0.051
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.950	0.050
E06.1 Subacute thyroiditis	0.001	0.951	0.048
E06.9 Thyroiditis, unspecified	0.001	0.959	0.041
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.961	0.039
K93.1 Megacolon in Chagas' disease	0.000	0.961	0.039
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.961	0.039
K91.5 Postcholecystectomy syndrome	0.000	0.965	0.035
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.968	0.031
K91.1 Postgastric surgery syndromes	0.000	0.969	0.031
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.971	0.028
J40-J47 Chronic lower respiratory diseases	0.000	0.975	0.025
K91.9 Postprocedural disorder of digestive system, unspecified	0.001	0.976	0.024
I61.9 Intracerebral haemorrhage, unspecified	0.024	0.976	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.977	0.023
J44 Other chronic obstructive pulmonary disease	0.000	0.978	0.022
J42 Unspecified chronic bronchitis	0.000	0.979	0.021
E06.3 Autoimmune thyroiditis	0.001	0.979	0.020
Z83.5 Family history of eye and ear disorders	0.000	0.979	0.021
J41 Simple and mucopurulent chronic bronchitis	0.000	0.979	0.020
J45 Asthma	0.000	0.980	0.020
J45.9 Asthma, unspecified	0.000	0.981	0.019
I61 Intracerebral haemorrhage	0.017	0.983	0.000
J41.0 Simple chronic bronchitis	0.000	0.983	0.017
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.984	0.016
I61.8 Other intracerebral haemorrhage	0.015	0.985	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.015	0.985	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.985	0.015
J41.1 Mucopurulent chronic bronchitis	0.000	0.985	0.015
J45.1 Nonallergic asthma	0.000	0.985	0.015
J45.8 Mixed asthma	0.000	0.985	0.015
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.014	0.986	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.014	0.986	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.986	0.014
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.014	0.986	0.000
N80.8 Other endometriosis	0.000	0.986	0.014
E04 Other non-toxic goitre	0.003	0.987	0.010
I61.6 Intracerebral haemorrhage, multiple localised	0.013	0.987	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.987	0.013
I61.4 Intracerebral haemorrhage in cerebellum	0.013	0.987	0.000
M80 Osteoporosis with pathological fracture	0.013	0.987	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.987	0.013
I61.3 Intracerebral haemorrhage in brain stem	0.013	0.987	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.013	0.987	0.000
N87.1 Moderate cervical dysplasia	0.013	0.987	0.000
J43 Emphysema	0.000	0.987	0.012
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.012	0.988	0.000
K72.9 Hepatic failure, unspecified	0.012	0.988	0.000
M84.0 Malunion of fracture	0.012	0.988	0.000
M84 Disorders of continuity of bone	0.012	0.988	0.000
M80-M85 Disorders of bone density and structure	0.012	0.988	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.011	0.989	0.000
M84.04 Malunion of fracture (Hand)	0.011	0.989	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.011	0.989	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.011	0.989	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.011	0.989	0.000
M84.02 Malunion of fracture (Upper arm)	0.011	0.989	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
M81 Osteoporosis without pathological fracture	0.010	0.990	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.010	0.990	0.000
K25.3 Acute without haemorrhage or perforation	0.010	0.990	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.990	0.010
J43.8 Other emphysema	0.000	0.990	0.010
E04.8 Other specified non-toxic goitre	0.002	0.990	0.007
M80.8 Other osteoporosis with pathological fracture	0.010	0.990	0.000
U80.1 Methicillin resistant agent	0.010	0.990	0.000
M85 Other disorders of bone density and structure	0.010	0.990	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.990	0.010
M80.0 Postmenopausal osteoporosis with pathological fracture	0.010	0.990	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.009	0.990	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.009	0.990	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.009	0.990	0.000
M84.3 Stress fracture, not elsewhere classified	0.009	0.990	0.000
M81.9 Osteoporosis, unspecified	0.009	0.991	0.000
M12 Other specific arthropathies	0.000	0.991	0.009
M08 Juvenile arthritis	0.000	0.991	0.009
J43.1 Panlobular emphysema	0.000	0.991	0.009
J43.0 MacLeod's syndrome	0.000	0.991	0.009
M84.4 Pathological fracture, not elsewhere classified	0.009	0.991	0.000
M84.09 Malunion of fracture (Site unspecified)	0.009	0.991	0.000
M84.08 Malunion of fracture (Other)	0.009	0.991	0.000
M84.00 Malunion of fracture (Multiple sites)	0.009	0.991	0.000
J45.0 Predominantly allergic asthma	0.000	0.991	0.009
M84.2 Delayed union of fracture	0.009	0.991	0.000
M83 Adult osteomalacia	0.009	0.991	0.000
M84.9 Disorder of continuity of bone, unspecified	0.008	0.991	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.991	0.009
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.009	0.991	0.000
M85.0 Fibrous dysplasia (monostotic)	0.009	0.991	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.008	0.991	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.008	0.992	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.008	0.992	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.008	0.992	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.008	0.992	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.008	0.992	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.008	0.992	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.008	0.992	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.008	0.992	0.000
J34.3 Hypertrophy of nasal turbinates	0.008	0.992	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.008	0.992	0.000
M84.01 Malunion of fracture (Shoulder region)	0.008	0.992	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.992	0.008
D69.0 Allergic purpura	0.000	0.992	0.008
H60.9 Otitis externa, unspecified	0.000	0.992	0.008
J43.2 Centrilobular emphysema	0.000	0.992	0.008
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.008	0.992	0.000
Z83 Family history of other specific disorders	0.000	0.992	0.008
M05 Seropositive rheumatoid arthritis	0.000	0.992	0.008
M85.2 Hyperostosis of skull	0.008	0.992	0.000
M85.9 Disorder of bone density and structure, unspecified	0.008	0.992	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.008	0.992	0.000
M84.8 Other disorders of continuity of bone	0.008	0.992	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.008	0.992	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.008	0.992	0.000
U80 Agent resistant to penicillin and related antibiotics	0.008	0.992	0.000
M81.98 Osteoporosis, unspecified (Other)	0.008	0.992	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.008	0.992	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.008	0.992	0.000
M81.8 Other osteoporosis	0.008	0.992	0.000
M81.2 Osteoporosis of disuse	0.008	0.992	0.000
D69.4 Other primary thrombocytopenia	0.000	0.992	0.008
Q05.9 Spina bifida, unspecified	0.000	0.992	0.008
M81.6 Localised osteoporosis [Lequesne]	0.007	0.992	0.000
M81.5 Idiopathic osteoporosis	0.007	0.992	0.000
M81.1 Postoophorectomy osteoporosis	0.007	0.992	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.007	0.992	0.000
M84.06 Malunion of fracture (Lower leg)	0.007	0.992	0.000
L71.9 Rosacea, unspecified	0.008	0.992	0.000
M11 Other crystal arthropathies	0.000	0.992	0.007
E04.0 Non-toxic diffuse goitre	0.003	0.993	0.004
M81.3 Postsurgical malabsorption osteoporosis	0.007	0.993	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.007	0.993	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M12.3 Palindromic rheumatism	0.000	0.993	0.007
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.007	0.993	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.993	0.007
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.993	0.007
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.993	0.007
M09.0 Juvenile arthritis in psoriasis	0.000	0.993	0.007
M85.5 Aneurysmal bone cyst	0.007	0.993	0.000
M85.4 Solitary bone cyst	0.007	0.993	0.000
M85.3 Osteitis condensans	0.007	0.993	0.000
M85.1 Skeletal fluorosis	0.007	0.993	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.007	0.993	0.000
M81.0 Postmenopausal osteoporosis	0.007	0.993	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.993	0.007
H60 Otitis externa	0.000	0.993	0.007
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.007	0.993	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.007	0.993	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.007	0.993	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.007	0.993	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.007	0.993	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.007	0.993	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.007	0.993	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.007	0.993	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.007	0.993	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.007	0.993	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.007	0.993	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.007	0.993	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.007	0.993	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.007	0.993	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.007	0.993	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.007	0.993	0.000
F20.0 Paranoid schizophrenia	0.007	0.993	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.007	0.993	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.993	0.007
M81.90 Osteoporosis, unspecified (Multiple sites)	0.007	0.993	0.000
J46 Status asthmaticus	0.000	0.993	0.007
M82 Osteoporosis in diseases classified elsewhere	0.007	0.993	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.000	0.993	0.007
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.993	0.007
M12.5 Traumatic arthropathy	0.000	0.993	0.007
M12.4 Intermittent hydrarthrosis	0.000	0.993	0.007
M12.1 Kaschin-Beck disease	0.000	0.993	0.007
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.993	0.007
M08.9 Juvenile arthritis, unspecified	0.000	0.993	0.007
M08.8 Other juvenile arthritis	0.000	0.993	0.007
M08.4 Pauciarticular juvenile arthritis	0.000	0.993	0.007
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.993	0.007
M08.2 Juvenile arthritis with systemic onset	0.000	0.993	0.007
M08.1 Juvenile ankylosing spondylitis	0.000	0.993	0.007
M81.4 Drug-induced osteoporosis	0.007	0.993	0.000
Z83.6 Family history of diseases of the respiratory system	0.000	0.993	0.007
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.007	0.993	0.000
M84.26 Delayed union of fracture (Lower leg)	0.007	0.993	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.007	0.993	0.000
M85.20 Hyperostosis of skull-Mult sites	0.007	0.993	0.000
M13 Other arthritis	0.000	0.993	0.007
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.007	0.993	0.000
K92 Other diseases of digestive system	0.000	0.993	0.007
M83.1 Senile osteomalacia	0.007	0.993	0.000
M14 Arthropathies in other diseases classified elsewhere	0.000	0.993	0.006
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.007	0.993	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.007	0.993	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.007	0.993	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.007	0.993	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.007	0.993	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.007	0.993	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.007	0.993	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.007	0.993	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.993	0.007
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.006	0.993	0.000
M84.28 Delayed union of fracture (Other)	0.006	0.993	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.006	0.993	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.006	0.993	0.000
M84.24 Delayed union of fracture (Hand)	0.006	0.993	0.000
M84.23 Delayed union of fracture (Forearm)	0.006	0.993	0.000
M84.22 Delayed union of fracture (Upper arm)	0.006	0.993	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.006	0.993	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.006	0.993	0.000
L40.9 Psoriasis, unspecified	0.007	0.993	0.000
M08.0 Juvenile rheumatoid arthritis	0.000	0.993	0.006
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.993	0.007
M83.9 Adult osteomalacia, unspecified	0.006	0.993	0.000
M83.5 Other drug-induced osteomalacia in adults	0.006	0.993	0.000
M83.4 Aluminum bone disease	0.006	0.993	0.000
M83.3 Adult osteomalacia due to malnutrition	0.006	0.993	0.000
M83.2 Adult osteomalacia due to malabsorption	0.006	0.993	0.000
M83.0 Puerperal osteomalacia	0.006	0.993	0.000
M07 Psoriatic and enteropathic arthropathies	0.000	0.993	0.006
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.993	0.007
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.006	0.994	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.006	0.994	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.006	0.994	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.006	0.994	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.006	0.994	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.006	0.994	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.006	0.994	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.006	0.994	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.006	0.994	0.000
M10 Gout	0.000	0.994	0.006
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.006	0.994	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.006	0.994	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.006	0.994	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.006	0.994	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.006	0.994	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.006	0.994	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.006	0.994	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.006	0.994	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.006	0.994	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.006	0.994	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.006	0.994	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.006	0.994	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.994	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.006	0.994	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.006	0.994	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.006	0.994	0.000
H60.1 Cellulitis of external ear	0.000	0.994	0.006
M83.8 Other adult osteomalacia	0.006	0.994	0.000
M84.03 Malunion of fracture (Forearm)	0.006	0.994	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.006	0.994	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.994	0.006
M12.2 Villonodular synovitis (pigmented)	0.000	0.994	0.006
M85.8 Other specified disorders of bone density and structure	0.006	0.994	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.000	0.994	0.006
Z83.0 Family history of human immunodeficiency virus [HIV]	0.000	0.994	0.006
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.994	0.006
M05.1 Rheumatoid lung disease	0.000	0.994	0.006
M05.0 Felty's syndrome	0.000	0.994	0.006
M85.29 Hyperostosis of skull-Site unspec	0.006	0.994	0.000
M85.28 Hyperostosis of skull-Other	0.006	0.994	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.006	0.994	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.006	0.994	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.006	0.994	0.000
M85.24 Hyperostosis of skull-Hand	0.006	0.994	0.000
M85.23 Hyperostosis of skull-Forearm	0.006	0.994	0.000
M85.22 Hyperostosis of skull-Upper arm	0.006	0.994	0.000
M85.21 Hyperostosis of skull-Shldr region	0.006	0.994	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.006	0.994	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.006	0.994	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.006	0.994	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.006	0.994	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.006	0.994	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.006	0.994	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.006	0.994	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.006	0.994	0.000
H60.3 Other infective otitis externa	0.000	0.994	0.006
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.006	0.994	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.994	0.006
M85.6 Other cyst of bone	0.006	0.994	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.994	0.006
M81.80 Other osteoporosis (Multiple sites)	0.006	0.994	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.006	0.994	0.000
H60.0 Abscess of external ear	0.000	0.994	0.006
M84.89 Other disorders of continuity of bone (Site unspecified)	0.006	0.994	0.000
M84.88 Other disorders of continuity of bone (Other)	0.006	0.994	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.006	0.994	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.006	0.994	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.006	0.994	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.006	0.994	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.006	0.994	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.006	0.994	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.006	0.994	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.006	0.994	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.006	0.994	0.000
M05.2 Rheumatoid vasculitis	0.000	0.994	0.006
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.006	0.994	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.006	0.994	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.006	0.994	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.006	0.994	0.000
M31.3 Wegener's granulomatosis	0.000	0.994	0.006
H60.5 Acute otitis externa, non-infective	0.000	0.994	0.006
M81.29 Osteoporosis of disuse (Site unspecified)	0.006	0.994	0.000
M81.28 Osteoporosis of disuse (Other)	0.006	0.994	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.006	0.994	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.006	0.994	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.006	0.994	0.000
M81.24 Osteoporosis of disuse (Hand)	0.006	0.994	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.006	0.994	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.006	0.994	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.006	0.994	0.000
M81.89 Other osteoporosis (Site unspecified)	0.006	0.994	0.000
M81.88 Other osteoporosis (Other)	0.006	0.994	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.006	0.994	0.000
M81.86 Other osteoporosis (Lower leg)	0.006	0.994	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.006	0.994	0.000
M81.84 Other osteoporosis (Hand)	0.006	0.994	0.000
M81.83 Other osteoporosis (Forearm)	0.006	0.994	0.000
M81.82 Other osteoporosis (Upper arm)	0.006	0.994	0.000
M81.81 Other osteoporosis (Shoulder region)	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations