TreeWAS – Variant ID: rs3129274

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
E10.9 Without complications	0.949	0.051	0.000
E10 Insulin-dependent diabetes mellitus	0.948	0.052	0.000
E10.3 With ophthalmic complications	0.944	0.056	0.000
E10.1 With ketoacidosis	0.846	0.154	0.000
E10.2 With renal complications	0.795	0.205	0.000
E10.6 With other specified complications	0.774	0.226	0.000
E10.0 With coma	0.748	0.252	0.000
E10.7 With multiple complications	0.736	0.264	0.000
E10.8 With unspecified complications	0.694	0.306	0.000
E10.5 With peripheral circulatory complications	0.679	0.321	0.000
J47 Bronchiectasis	0.574	0.426	0.000
K90 Intestinal malabsorption	0.501	0.499	0.000
E10.4 With neurological complications	0.392	0.607	0.000
K90.9 Intestinal malabsorption, unspecified	0.374	0.626	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.361	0.639	0.000
K90.3 Pancreatic steatorrhoea	0.359	0.641	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.359	0.641	0.000
K90.1 Tropical sprue	0.359	0.641	0.000
K90.8 Other intestinal malabsorption	0.356	0.644	0.000
E10-E14 Diabetes mellitus	0.184	0.816	0.000
E53.8 Deficiency of other specified B group vitamins	0.152	0.848	0.000
E53 Deficiency of other B group vitamins	0.145	0.855	0.000
E50-E64 Other nutritional deficiencies	0.138	0.862	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.137	0.863	0.000
E12 Malnutrition-related diabetes mellitus	0.132	0.868	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.124	0.876	0.000
E16 Other disorders of pancreatic internal secretion	0.114	0.886	0.000
E13 Other specified diabetes mellitus	0.113	0.887	0.000
E53.9 Vitamin B deficiency, unspecified	0.112	0.888	0.000
E16.2 Hypoglycaemia, unspecified	0.109	0.891	0.000
E58 Dietary calcium deficiency	0.108	0.892	0.000
F20.9 Schizophrenia, unspecified	0.000	0.894	0.106
E51 Thiamine deficiency	0.104	0.896	0.000
E53.1 Pyridoxine deficiency	0.104	0.896	0.000
E53.0 Riboflavin deficiency	0.104	0.896	0.000
F20 Schizophrenia	0.000	0.896	0.104
K90-K93 Other diseases of the digestive system	0.103	0.897	0.000
E20-E35 Disorders of other endocrine glands	0.103	0.897	0.000
F20.0 Paranoid schizophrenia	0.000	0.897	0.103
E54 Ascorbic acid deficiency	0.101	0.898	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.099	0.901	0.000
E63 Other nutritional deficiencies	0.099	0.901	0.000
E56 Other vitamin deficiencies	0.099	0.901	0.000
E50 Vitamin A deficiency	0.099	0.901	0.000
E60 Dietary zinc deficiency	0.099	0.901	0.000
E59 Dietary selenium deficiency	0.099	0.901	0.000
E52 Niacin deficiency [pellagra]	0.099	0.901	0.000
E40-E46 Malnutrition	0.097	0.903	0.000
E12.9 Without complications	0.095	0.905	0.000
E12.8 With unspecified complications	0.095	0.905	0.000
E12.7 With multiple complications	0.095	0.905	0.000
E12.6 With other specified complications	0.095	0.905	0.000
E12.5 With peripheral circulatory complications	0.095	0.905	0.000
E12.4 With neurological complications	0.095	0.905	0.000
E12.3 With ophthalmic complications	0.095	0.905	0.000
E12.2 With renal complications	0.095	0.905	0.000
E12.1 With ketoacidosis	0.095	0.905	0.000
E12.0 With coma	0.095	0.905	0.000
E22 Hyperfunction of pituitary gland	0.094	0.906	0.000
E15 Nondiabetic hypoglycaemic coma	0.089	0.911	0.000
E27.1 Primary adrenocortical insufficiency	0.089	0.911	0.000
E27 Other disorders of adrenal gland	0.087	0.913	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.087	0.913	0.000
E28 Ovarian dysfunction	0.087	0.913	0.000
K91.4 Colostomy and enterostomy malfunction	0.085	0.915	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.085	0.915	0.000
E29 Testicular dysfunction	0.082	0.917	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.082	0.918	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.082	0.918	0.000
E16.4 Abnormal secretion of gastrin	0.082	0.918	0.000
E16.3 Increased secretion of glucagon	0.082	0.918	0.000
E13.8 With unspecified complications	0.081	0.919	0.000
E13.7 With multiple complications	0.081	0.919	0.000
E13.6 With other specified complications	0.081	0.919	0.000
E13.5 With peripheral circulatory complications	0.081	0.919	0.000
E13.4 With neurological complications	0.081	0.919	0.000
E13.2 With renal complications	0.081	0.919	0.000
E13.1 With ketoacidosis	0.081	0.919	0.000
E13.0 With coma	0.081	0.919	0.000
E55 Vitamin D deficiency	0.081	0.919	0.000
E26 Hyperaldosteronism	0.081	0.919	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.919	0.081
E22.1 Hyperprolactinaemia	0.080	0.920	0.000
E51.2 Wernicke's encephalopathy	0.080	0.920	0.000
E13.3 With ophthalmic complications	0.079	0.921	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.079	0.921	0.000
E31 Polyglandular dysfunction	0.078	0.922	0.000
F25 Schizoaffective disorders	0.000	0.924	0.076
F22 Persistent delusional disorders	0.000	0.924	0.076
E51.9 Thiamine deficiency, unspecified	0.075	0.925	0.000
E51.8 Other manifestations of thiamine deficiency	0.075	0.925	0.000
E51.1 Beriberi	0.075	0.925	0.000
E28.3 Primary ovarian failure	0.075	0.925	0.000
E20 Hypoparathyroidism	0.075	0.925	0.000
F20.8 Other schizophrenia	0.000	0.925	0.075
F20.6 Simple schizophrenia	0.000	0.925	0.075
F20.4 Postschizophrenic depression	0.000	0.925	0.075
F20.3 Undifferentiated schizophrenia	0.000	0.925	0.075
F20.2 Catatonic schizophrenia	0.000	0.925	0.075
F20.1 Hebephrenic schizophrenia	0.000	0.925	0.075
K93 Disorders of other digestive organs in diseases classified elsewhere	0.074	0.926	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.074	0.926	0.000
E32 Diseases of thymus	0.074	0.926	0.000
E30 Disorders of puberty, not elsewhere classified	0.074	0.926	0.000
F22.0 Delusional disorder	0.000	0.926	0.074
F20.5 Residual schizophrenia	0.000	0.928	0.072
E50.9 Vitamin A deficiency, unspecified	0.071	0.928	0.000
E50.8 Other manifestations of vitamin A deficiency	0.071	0.928	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.071	0.928	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.071	0.928	0.000
E50.5 Vitamin A deficiency with night blindness	0.071	0.928	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.071	0.928	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.071	0.928	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.071	0.928	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.071	0.928	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.071	0.928	0.000
E56.9 Vitamin deficiency, unspecified	0.071	0.928	0.000
E56.8 Deficiency of other vitamins	0.071	0.928	0.000
E56.1 Deficiency of vitamin K	0.071	0.928	0.000
E56.0 Deficiency of vitamin E	0.071	0.928	0.000
E63.9 Nutritional deficiency, unspecified	0.071	0.928	0.000
E63.8 Other specified nutritional deficiencies	0.071	0.928	0.000
E63.1 Imbalance of constituents of food intake	0.071	0.928	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.071	0.928	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.071	0.928	0.000
E64.8 Sequelae of other nutritional deficiencies	0.071	0.928	0.000
E64.3 Sequelae of rickets	0.071	0.928	0.000
E64.2 Sequelae of vitamin C deficiency	0.071	0.928	0.000
E64.1 Sequelae of vitamin A deficiency	0.071	0.928	0.000
E64.0 Sequelae of protein-energy malnutrition	0.071	0.928	0.000
E16.1 Other hypoglycaemia	0.071	0.929	0.000
E61 Deficiency of other nutrient elements	0.070	0.930	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.070	0.930	0.000
E45 Retarded development following protein-energy malnutrition	0.070	0.930	0.000
E43 Unspecified severe protein-energy malnutrition	0.070	0.930	0.000
E42 Marasmic kwashiorkor	0.070	0.930	0.000
E41 Nutritional marasmus	0.070	0.930	0.000
E40 Kwashiorkor	0.070	0.930	0.000
E46 Unspecified protein-energy malnutrition	0.068	0.932	0.000
E29.1 Testicular hypofunction	0.068	0.932	0.000
E34 Other endocrine disorders	0.068	0.932	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.067	0.933	0.000
E22.8 Other hyperfunction of pituitary gland	0.067	0.933	0.000
E25 Adrenogenital disorders	0.066	0.934	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.934	0.066
E27.2 Addisonian crisis	0.066	0.934	0.000
E27.9 Disorder of adrenal gland, unspecified	0.065	0.935	0.000
E13.9 Without complications	0.065	0.935	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.937	0.063
E28.2 Polycystic ovarian syndrome	0.063	0.937	0.000
E27.5 Adrenomedullary hyperfunction	0.063	0.937	0.000
E27.0 Other adrenocortical overactivity	0.063	0.937	0.000
F25.1 Schizoaffective disorder, depressive type	0.000	0.937	0.063
E28.9 Ovarian dysfunction, unspecified	0.062	0.938	0.000
E28.8 Other ovarian dysfunction	0.062	0.938	0.000
E28.1 Androgen excess	0.062	0.938	0.000
E28.0 Oestrogen excess	0.062	0.938	0.000
E26.0 Primary hyperaldosteronism	0.062	0.938	0.000
E26.9 Hyperaldosteronism, unspecified	0.061	0.938	0.000
E31.0 Autoimmune polyglandular failure	0.060	0.940	0.000
E29.9 Testicular dysfunction, unspecified	0.059	0.941	0.000
E29.8 Other testicular dysfunction	0.059	0.941	0.000
E29.0 Testicular hyperfunction	0.059	0.941	0.000
E55.0 Rickets, active	0.058	0.942	0.000
E26.8 Other hyperaldosteronism	0.058	0.942	0.000
E26.1 Secondary hyperaldosteronism	0.058	0.942	0.000
F28 Other nonorganic psychotic disorders	0.000	0.942	0.058
F24 Induced delusional disorder	0.000	0.942	0.058
F21 Schizotypal disorder	0.000	0.942	0.058
E24 Cushing's syndrome	0.058	0.942	0.000
E14 Unspecified diabetes mellitus	0.057	0.943	0.000
E22.0 Acromegaly and pituitary gigantism	0.057	0.943	0.000
W19.9 Unspecified place	0.057	0.943	0.000
E31.9 Polyglandular dysfunction, unspecified	0.056	0.944	0.000
E31.8 Other polyglandular dysfunction	0.056	0.944	0.000
E31.1 Polyglandular hyperfunction	0.056	0.944	0.000
E00-E07 Disorders of thyroid gland	0.056	0.944	0.000
K91.5 Postcholecystectomy syndrome	0.055	0.945	0.000
F25.8 Other schizoaffective disorders	0.000	0.945	0.055
F25.2 Schizoaffective disorder, mixed type	0.000	0.945	0.055
E20.9 Hypoparathyroidism, unspecified	0.054	0.945	0.000
F22.8 Other persistent delusional disorders	0.000	0.945	0.054
E05 Thyrotoxicosis [hyperthyroidism]	0.054	0.946	0.000
E20.8 Other hypoparathyroidism	0.054	0.946	0.000
E20.1 Pseudohypoparathyroidism	0.054	0.946	0.000
E20.0 Idiopathic hypoparathyroidism	0.054	0.946	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.054	0.946	0.000
E34.3 Short stature, not elsewhere classified	0.053	0.946	0.000
G62.9 Polyneuropathy, unspecified	0.053	0.947	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.053	0.947	0.000
K93.1 Megacolon in Chagas' disease	0.053	0.947	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.053	0.947	0.000
E30.9 Disorder of puberty, unspecified	0.053	0.947	0.000
E30.8 Other disorders of puberty	0.053	0.947	0.000
E30.1 Precocious puberty	0.053	0.947	0.000
E30.0 Delayed puberty	0.053	0.947	0.000
E32.9 Disease of thymus, unspecified	0.053	0.947	0.000
E32.8 Other diseases of thymus	0.053	0.947	0.000
E32.1 Abscess of thymus	0.053	0.947	0.000
E32.0 Persistent hyperplasia of thymus	0.053	0.947	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.053	0.947	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.053	0.947	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.053	0.947	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.052	0.948	0.000
E61.9 Deficiency of nutrient element, unspecified	0.050	0.950	0.000
E61.8 Deficiency of other specified nutrient elements	0.050	0.950	0.000
E61.7 Deficiency of multiple nutrient elements	0.050	0.950	0.000
E61.6 Vanadium deficiency	0.050	0.950	0.000
E61.5 Molybdenum deficiency	0.050	0.950	0.000
E61.4 Chromium deficiency	0.050	0.950	0.000
E61.3 Manganese deficiency	0.050	0.950	0.000
E61.0 Copper deficiency	0.050	0.950	0.000
E44.1 Mild protein-energy malnutrition	0.050	0.950	0.000
E44.0 Moderate protein-energy malnutrition	0.050	0.950	0.000
E61.2 Magnesium deficiency	0.050	0.950	0.000
E34.5 Androgen resistance syndrome	0.049	0.951	0.000
E34.4 Constitutional tall stature	0.049	0.951	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.049	0.951	0.000
E34.1 Other hypersecretion of intestinal hormones	0.049	0.951	0.000
E34.9 Endocrine disorder, unspecified	0.049	0.951	0.000
E65-E68 Obesity and other hyperalimentation	0.048	0.952	0.000
E25.9 Adrenogenital disorder, unspecified	0.047	0.952	0.000
E25.8 Other adrenogenital disorders	0.047	0.952	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.952	0.047
E05.9 Thyrotoxicosis, unspecified	0.047	0.953	0.000
K91.1 Postgastric surgery syndromes	0.047	0.953	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.045	0.954	0.000
E14.8 With unspecified complications	0.045	0.955	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.044	0.956	0.000
E34.8 Other specified endocrine disorders	0.044	0.956	0.000
E14.1 With ketoacidosis	0.043	0.957	0.000
E24.8 Other Cushing's syndrome	0.043	0.957	0.000
E24.2 Drug-induced Cushing's syndrome	0.042	0.957	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.041	0.958	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.041	0.958	0.000
E24.3 Ectopic ACTH syndrome	0.041	0.958	0.000
E24.1 Nelson's syndrome	0.041	0.958	0.000
E14.7 With multiple complications	0.041	0.959	0.000
E14.0 With coma	0.041	0.959	0.000
E34.0 Carcinoid syndrome	0.041	0.959	0.000
E14.2 Withrenal complications	0.040	0.960	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.040	0.960	0.000
E00 Congenital iodine-deficiency syndrome	0.040	0.960	0.000
E14.6 With other specified complications	0.040	0.960	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.039	0.960	0.000
E55.9 Vitamin D deficiency, unspecified	0.040	0.960	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.039	0.961	0.000
E05.5 Thyroid crisis or storm	0.039	0.961	0.000
E05.4 Thyrotoxicosis factitia	0.039	0.961	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.039	0.961	0.000
E14.3 With ophthalmic complications	0.038	0.962	0.000
G62 Other polyneuropathies	0.037	0.963	0.000
Q00-Q07 Congenital malformations of the nervous system	0.037	0.963	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.037	0.963	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.037	0.963	0.000
F23 Acute and transient psychotic disorders	0.001	0.963	0.036
E14.5 With peripheral circulatory complications	0.036	0.964	0.000
K91.3 Postoperative intestinal obstruction	0.036	0.964	0.000
Q05 Spina bifida	0.036	0.964	0.000
E06 Thyroiditis	0.036	0.964	0.000
Q05.9 Spina bifida, unspecified	0.035	0.965	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.035	0.965	0.000
E24.0 Pituitary-dependent Cushing's disease	0.035	0.965	0.000
E67 Other hyperalimentation	0.035	0.965	0.000
E68 Sequelae of hyperalimentation	0.035	0.965	0.000
Q07 Other congenital malformations of nervous system	0.033	0.967	0.000
E14.4 With neurological complications	0.032	0.968	0.000
E24.9 Cushing's syndrome, unspecified	0.032	0.968	0.000
G62.0 Drug-induced polyneuropathy	0.031	0.968	0.000
Q04 Other congenital malformations of brain	0.031	0.969	0.000
F29 Unspecified nonorganic psychosis	0.000	0.969	0.030
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.030	0.970	0.000
E07 Other disorders of thyroid	0.030	0.970	0.000
G62.8 Other specified polyneuropathies	0.030	0.970	0.000
E05.8 Other thyrotoxicosis	0.030	0.970	0.000
Q07.0 Arnold-Chiari syndrome	0.030	0.970	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.030	0.970	0.000
Q50-Q56 Congenital malformations of genital organs	0.029	0.971	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.029	0.971	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.029	0.971	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.029	0.971	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.029	0.971	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.029	0.971	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.029	0.971	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.029	0.971	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.029	0.971	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.029	0.971	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.029	0.971	0.000
Q35-Q37 Cleft lip and cleft palate	0.029	0.971	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.029	0.971	0.000
E27.8 Other specified disorders of adrenal gland	0.028	0.971	0.001
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.028	0.971	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.028	0.971	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.028	0.972	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.028	0.972	0.000
E06.5 Other chronic thyroiditis	0.027	0.972	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.027	0.973	0.000
E65 Localised adiposity	0.027	0.973	0.000
Q80-Q89 Other congenital malformations	0.027	0.973	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.027	0.973	0.000
G62.2 Polyneuropathy due to other toxic agents	0.027	0.973	0.000
Q06 Other congenital malformations of spinal cord	0.027	0.973	0.000
Q01 Encephalocele	0.027	0.973	0.000
Q00 Anencephaly and similar malformations	0.027	0.973	0.000
Q02 Microcephaly	0.027	0.973	0.000
F23.8 Other acute and transient psychotic disorders	0.001	0.973	0.026
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.973	0.026
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.973	0.026
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.001	0.973	0.026
E06.9 Thyroiditis, unspecified	0.026	0.973	0.000
Q40 Other congenital malformations of upper alimentary tract	0.026	0.974	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.026	0.974	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.026	0.974	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.026	0.974	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.026	0.974	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.026	0.974	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.026	0.974	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.026	0.974	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.026	0.974	0.000
Q04.8 Other specified congenital malformations of brain	0.026	0.974	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.026	0.974	0.000
Q03 Congenital hydrocephalus	0.026	0.974	0.000
G62.1 Alcoholic polyneuropathy	0.026	0.974	0.000
E06.4 Drug-induced thyroiditis	0.026	0.974	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.026	0.974	0.000
E06.1 Subacute thyroiditis	0.026	0.974	0.000
E06.0 Acute thyroiditis	0.026	0.974	0.000
Q07.8 Other specified congenital malformations of nervous system	0.025	0.974	0.000
E67.8 Other specified hyperalimentation	0.025	0.975	0.000
E67.3 Hypervitaminosis D	0.025	0.975	0.000
E67.2 Megavitamin-B6 syndrome	0.025	0.975	0.000
E67.1 Hypercarotenaemia	0.025	0.975	0.000
E67.0 Hypervitaminosis A	0.025	0.975	0.000
Q27 Other congenital malformations of peripheral vascular system	0.025	0.975	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.001	0.975	0.024
Q96 Turner's syndrome	0.024	0.976	0.000
Q35 Cleft palate	0.024	0.976	0.000
Q18 Other congenital malformations of face and neck	0.024	0.976	0.000
Q04.6 Congenital cerebral cysts	0.024	0.976	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.024	0.976	0.000
Q27.3 Peripheral arteriovenous malformation	0.024	0.976	0.000
E23 Hypofunction and other disorders of pituitary gland	0.023	0.976	0.001
Q65 Congenital deformities of hip	0.023	0.977	0.000
Q39 Congenital malformations of oesophagus	0.023	0.977	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.023	0.977	0.000
E89.2 Postprocedural hypoparathyroidism	0.023	0.977	0.000
Q17 Other congenital malformations of ear	0.023	0.977	0.000
Q31 Congenital malformations of larynx	0.023	0.977	0.000
Q99.8 Other specified chromosome abnormalities	0.023	0.977	0.000
Q68 Other congenital musculoskeletal deformities	0.023	0.977	0.000
Q24 Other congenital malformations of heart	0.023	0.977	0.000
Q40.2 Other specified congenital malformations of stomach	0.023	0.977	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.023	0.977	0.000
Q04.9 Congenital malformation of brain, unspecified	0.023	0.977	0.000
Q04.5 Megalencephaly	0.023	0.977	0.000
Q04.4 Septo-optic dysplasia	0.023	0.977	0.000
Q04.3 Other reduction deformities of brain	0.023	0.977	0.000
Q04.2 Holoprosencephaly	0.023	0.977	0.000
Q04.1 Arhinencephaly	0.023	0.977	0.000
Q04.0 Congenital malformations of corpus callosum	0.023	0.977	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.022	0.978	0.000
Q12 Congenital lens malformations	0.022	0.978	0.000
Q85 Phakomatoses, not elsewhere classified	0.022	0.978	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.022	0.978	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.022	0.978	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.022	0.978	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.022	0.978	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.022	0.978	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.022	0.978	0.000
Q90 Down's syndrome	0.022	0.978	0.000
E07.1 Dyshormogenetic goitre	0.022	0.978	0.000
E07.0 Hypersecretion of calcitonin	0.022	0.978	0.000
Q28 Other congenital malformations of circulatory system	0.022	0.978	0.000
Q45 Other congenital malformations of digestive system	0.021	0.978	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.021	0.978	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.021	0.978	0.000
Q55 Other congenital malformations of male genital organs	0.021	0.978	0.000
Q43 Other congenital malformations of intestine	0.021	0.978	0.000
Q76 Congenital malformations of spine and bony thorax	0.021	0.978	0.000
Q30 Congenital malformations of nose	0.021	0.979	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.021	0.979	0.000
E89.0 Postprocedural hypothyroidism	0.021	0.979	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.021	0.979	0.000
Q52 Other congenital malformations of female genitalia	0.021	0.979	0.000
Q53 Undescended testicle	0.021	0.979	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.021	0.979	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.021	0.979	0.000
Q13 Congenital malformations of anterior segment of eye	0.021	0.979	0.000
Q89 Other congenital malformations, not elsewhere classified	0.021	0.979	0.000
Q35.9 Cleft palate, unspecified	0.021	0.979	0.000
F99 Mental disorder, not otherwise specified	0.000	0.979	0.021
Q37 Cleft palate with cleft lip	0.021	0.979	0.000
Q36 Cleft lip	0.021	0.979	0.000
E61.1 Iron deficiency	0.021	0.979	0.000
E70-E90 Metabolic disorders	0.021	0.979	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.021	0.979	0.000
Q50.3 Other congenital malformations of ovary	0.021	0.979	0.000
Q50.2 Congenital torsion of ovary	0.021	0.979	0.000
Q50.1 Developmental ovarian cyst	0.021	0.979	0.000
Q50.0 Congenital absence of ovary	0.021	0.979	0.000
Q34 Other congenital malformations of respiratory system	0.021	0.979	0.000
Q33 Congenital malformations of lung	0.021	0.979	0.000
Q32 Congenital malformations of trachea and bronchus	0.021	0.979	0.000
Q15 Other congenital malformations of eye	0.021	0.979	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.020	0.980	0.000
Q40.1 Congenital hiatus hernia	0.020	0.980	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.020	0.980	0.000
Q75 Other congenital malformations of skull and face bones	0.020	0.980	0.000
Q73 Reduction defects of unspecified limb	0.020	0.980	0.000
Q72 Reduction defects of lower limb	0.020	0.980	0.000
Q71 Reduction defects of upper limb	0.020	0.980	0.000
Q70 Syndactyly	0.020	0.980	0.000
Q69 Polydactyly	0.020	0.980	0.000
Q65.8 Other congenital deformities of hip	0.020	0.980	0.000
Q96.9 Turner's syndrome, unspecified	0.020	0.980	0.000
Q54 Hypospadias	0.020	0.980	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.020	0.980	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.020	0.980	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.020	0.980	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.020	0.980	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.020	0.980	0.000
Q87.4 Marfan's syndrome	0.020	0.980	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.020	0.980	0.000
Q84 Other congenital malformations of integument	0.020	0.980	0.000
Q81 Epidermolysis bullosa	0.020	0.980	0.000
Q80 Congenital ichthyosis	0.020	0.980	0.000
Q26 Congenital malformations of great veins	0.020	0.980	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.020	0.980	0.000
Q00.2 Iniencephaly	0.019	0.980	0.000
Q00.1 Craniorachischisis	0.019	0.980	0.000
Q00.0 Anencephaly	0.019	0.980	0.000
Q01.9 Encephalocele, unspecified	0.019	0.980	0.000
Q01.8 Encephalocele of other sites	0.019	0.980	0.000
Q01.2 Occipital encephalocele	0.019	0.980	0.000
Q01.1 Nasofrontal encephalocele	0.019	0.980	0.000
Q01.0 Frontal encephalocele	0.019	0.980	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.019	0.980	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.019	0.980	0.000
Q06.4 Hydromyelia	0.019	0.980	0.000
Q06.3 Other congenital cauda equina malformations	0.019	0.980	0.000
Q06.2 Diastematomyelia	0.019	0.980	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.019	0.980	0.000
Q06.0 Amyelia	0.019	0.980	0.000
Q67.6 Pectus excavatum	0.019	0.980	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.019	0.980	0.000
Q18.1 Preauricular sinus and cyst	0.019	0.981	0.000
Q39.6 Diverticulum of oesophagus	0.019	0.981	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.019	0.981	0.000
Q14 Congenital malformations of posterior segment of eye	0.019	0.981	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.019	0.981	0.000
Q31.3 Laryngocele	0.019	0.981	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.019	0.981	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.019	0.981	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.019	0.981	0.000
Q17.5 Prominent ear	0.019	0.981	0.000
Q99.9 Chromosomal abnormality, unspecified	0.019	0.981	0.000
Q99.2 Fragile X chromosome	0.019	0.981	0.000
Q99.1 46,XX true hermaphrodite	0.019	0.981	0.000
Q99.0 Chimera 46,XX/46,XY	0.019	0.981	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.019	0.981	0.000
Q03.8 Other congenital hydrocephalus	0.019	0.981	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.019	0.981	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.019	0.981	0.000
Q74 Other congenital malformations of limb(s)	0.018	0.981	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.018	0.981	0.000
E07.9 Disorder of thyroid, unspecified	0.018	0.982	0.000
Q27.4 Congenital phlebectasia	0.018	0.982	0.000
Q27.2 Other congenital malformations of renal artery	0.018	0.982	0.000
Q27.1 Congenital renal artery stenosis	0.018	0.982	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.018	0.982	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.018	0.982	0.000
Q24.8 Other specified congenital malformations of heart	0.018	0.982	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.018	0.982	0.000
Q50.5 Embryonic cyst of broad ligament	0.018	0.982	0.000
Q28.3 Other malformations of cerebral vessels	0.018	0.982	0.000
Q67.5 Congenital deformity of spine	0.018	0.982	0.000
Q96.8 Other variants of Turner's syndrome	0.018	0.982	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.018	0.982	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.018	0.982	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.018	0.982	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.018	0.982	0.000
Q96.0 Karyotype 45,X	0.018	0.982	0.000
F99-F99 Unspecified mental disorder	0.000	0.982	0.018
Q53.2 Undescended testicle, bilateral	0.018	0.982	0.000
Q82 Other congenital malformations of skin	0.018	0.982	0.000
Q35.8 (Cleft palate, unspecified, bilateral)	0.017	0.982	0.000
Q35.7 Cleft uvula	0.017	0.982	0.000
Q35.6 Cleft palate, medial	0.017	0.982	0.000
Q35.5 Cleft hard palate with cleft soft palate	0.017	0.982	0.000
Q35.4 (Cleft hard palate with cleft soft palate, bilateral)	0.017	0.982	0.000
Q35.3 Cleft soft palate	0.017	0.982	0.000
Q35.2 (Cleft soft palate, bilateral)	0.017	0.982	0.000
Q35.1 Cleft hard palate	0.017	0.982	0.000
Q35.0 (Cleft hard palate, bilateral)	0.017	0.982	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.017	0.982	0.000
Q18.8 Other specified congenital malformations of face and neck	0.017	0.982	0.000
Q18.7 Microcheilia	0.017	0.982	0.000
Q18.6 Macrocheilia	0.017	0.982	0.000
Q18.5 Microstomia	0.017	0.982	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations