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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129793
log Bayes Factor = 53.0775
Chromosome 6   position 28,970,176  (GRCh37) Explore rs3129793 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
E16.2 Hypoglycaemia, unspecified
0.000 0.004 0.996
E16 Other disorders of pancreatic internal secretion
0.000 0.005 0.995
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.006 0.994
E00-E07 Disorders of thyroid gland
0.000 0.006 0.994
E10.2 With renal complications
0.000 0.048 0.952
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.048 0.952
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.929 0.071 0.000
E10.4 With neurological complications
0.000 0.090 0.910
E10.1 With ketoacidosis
0.000 0.102 0.898
E05.8 Other thyrotoxicosis
0.000 0.187 0.813
E13 Other specified diabetes mellitus
0.000 0.197 0.802
E16.1 Other hypoglycaemia
0.000 0.223 0.777
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.237 0.763
E10.7 With multiple complications
0.000 0.251 0.749
E40-E46 Malnutrition
0.000 0.276 0.724
E10.0 With coma
0.000 0.279 0.721
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.286 0.714
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.286 0.714
E16.4 Abnormal secretion of gastrin
0.000 0.286 0.714
E16.3 Increased secretion of glucagon
0.000 0.286 0.714
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.287 0.713
E00 Congenital iodine-deficiency syndrome
0.000 0.287 0.713
E14 Unspecified diabetes mellitus
0.000 0.302 0.698
E10.5 With peripheral circulatory complications
0.000 0.329 0.671
E10.6 With other specified complications
0.000 0.333 0.667
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.333 0.667
E13.9 Without complications
0.000 0.339 0.661
E06 Thyroiditis
0.000 0.388 0.612
E07 Other disorders of thyroid
0.000 0.388 0.612
E14.3 With ophthalmic complications
0.000 0.410 0.590
E13.3 With ophthalmic complications
0.000 0.421 0.579
E13.8 With unspecified complications
0.000 0.424 0.575
E13.7 With multiple complications
0.000 0.424 0.575
E13.6 With other specified complications
0.000 0.424 0.575
E13.5 With peripheral circulatory complications
0.000 0.424 0.575
E13.4 With neurological complications
0.000 0.424 0.575
E13.2 With renal complications
0.000 0.424 0.575
E13.1 With ketoacidosis
0.000 0.424 0.575
E13.0 With coma
0.000 0.424 0.575
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.427 0.573
E14.1 With ketoacidosis
0.000 0.437 0.563
E03 Other hypothyroidism
0.000 0.463 0.537
E14.6 With other specified complications
0.000 0.469 0.531
E46 Unspecified protein-energy malnutrition
0.000 0.471 0.529
E14.8 With unspecified complications
0.000 0.474 0.526
E14.4 With neurological complications
0.000 0.481 0.519
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.481 0.519
E45 Retarded development following protein-energy malnutrition
0.000 0.481 0.519
E43 Unspecified severe protein-energy malnutrition
0.000 0.481 0.519
E42 Marasmic kwashiorkor
0.000 0.481 0.519
E41 Nutritional marasmus
0.000 0.481 0.519
E40 Kwashiorkor
0.000 0.481 0.519
E12.9 Without complications
0.000 0.487 0.512
E12.8 With unspecified complications
0.000 0.487 0.512
E12.7 With multiple complications
0.000 0.487 0.512
E12.6 With other specified complications
0.000 0.487 0.512
E12.5 With peripheral circulatory complications
0.000 0.487 0.512
E12.4 With neurological complications
0.000 0.487 0.512
E12.3 With ophthalmic complications
0.000 0.487 0.512
E12.2 With renal complications
0.000 0.487 0.512
E12.1 With ketoacidosis
0.000 0.487 0.512
E12.0 With coma
0.000 0.487 0.512
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.511
E06.9 Thyroiditis, unspecified
0.000 0.492 0.508
E10.8 With unspecified complications
0.000 0.493 0.507
E14.7 With multiple complications
0.000 0.499 0.501
E07.8 Other specified disorders of thyroid
0.000 0.517 0.483
E14.2 Withrenal complications
0.000 0.522 0.477
E14.5 With peripheral circulatory complications
0.000 0.528 0.472
E14.0 With coma
0.000 0.531 0.469
E06.1 Subacute thyroiditis
0.000 0.540 0.460
E06.4 Drug-induced thyroiditis
0.000 0.561 0.439
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.561 0.439
E06.0 Acute thyroiditis
0.000 0.561 0.439
E07.1 Dyshormogenetic goitre
0.000 0.561 0.439
E07.0 Hypersecretion of calcitonin
0.000 0.561 0.439
E06.5 Other chronic thyroiditis
0.000 0.579 0.421
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.583 0.416
K90 Intestinal malabsorption
0.000 0.587 0.413
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.592 0.408
E03.5 Myxoedema coma
0.000 0.614 0.385
E03.4 Atrophy of thyroid (acquired)
0.000 0.614 0.385
E03.3 Postinfectious hypothyroidism
0.000 0.614 0.385
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.615 0.385
E44.1 Mild protein-energy malnutrition
0.000 0.628 0.372
E44.0 Moderate protein-energy malnutrition
0.000 0.628 0.372
E03.1 Congenital hypothyroidism without goitre
0.000 0.629 0.370
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.649 0.351
E50-E64 Other nutritional deficiencies
0.000 0.651 0.349
E03.8 Other specified hypothyroidism
0.000 0.674 0.326
E65-E68 Obesity and other hyperalimentation
0.000 0.680 0.320
K90.3 Pancreatic steatorrhoea
0.000 0.704 0.296
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.704 0.296
K90.1 Tropical sprue
0.000 0.704 0.296
K90.8 Other intestinal malabsorption
0.000 0.717 0.283
E03.9 Hypothyroidism, unspecified
0.000 0.731 0.269
E54 Ascorbic acid deficiency
0.000 0.746 0.254
E11 Non-insulin-dependent diabetes mellitus
0.000 0.748 0.252
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.750 0.250
E63 Other nutritional deficiencies
0.000 0.750 0.250
E50 Vitamin A deficiency
0.000 0.750 0.250
E60 Dietary zinc deficiency
0.000 0.750 0.250
E59 Dietary selenium deficiency
0.000 0.750 0.250
E52 Niacin deficiency [pellagra]
0.000 0.750 0.250
E51 Thiamine deficiency
0.000 0.752 0.248
E07.9 Disorder of thyroid, unspecified
0.000 0.757 0.243
E56 Other vitamin deficiencies
0.000 0.764 0.236
E67 Other hyperalimentation
0.000 0.770 0.230
E68 Sequelae of hyperalimentation
0.000 0.770 0.230
E11.6 With other specified complications
0.000 0.771 0.229
E58 Dietary calcium deficiency
0.000 0.772 0.227
E11.1 With ketoacidosis
0.000 0.779 0.221
E55 Vitamin D deficiency
0.000 0.780 0.220
E11.0 With coma
0.000 0.791 0.209
M45.X9 Ankylosing spondylitis (Site unspecified)
0.208 0.792 0.000
E61 Deficiency of other nutrient elements
0.000 0.799 0.201
K90.9 Intestinal malabsorption, unspecified
0.000 0.799 0.201
I83 Varicose veins of lower extremities
0.191 0.809 0.000
E11.2 With renal complications
0.000 0.819 0.181
E11.7 With multiple complications
0.000 0.819 0.181
E50.9 Vitamin A deficiency, unspecified
0.000 0.820 0.179
E50.8 Other manifestations of vitamin A deficiency
0.000 0.820 0.179
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.820 0.179
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.820 0.179
E50.5 Vitamin A deficiency with night blindness
0.000 0.820 0.179
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.820 0.179
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.820 0.179
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.820 0.179
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.820 0.179
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.820 0.179
E63.9 Nutritional deficiency, unspecified
0.000 0.820 0.179
E63.8 Other specified nutritional deficiencies
0.000 0.820 0.179
E63.1 Imbalance of constituents of food intake
0.000 0.820 0.179
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.820 0.179
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.820 0.179
E64.8 Sequelae of other nutritional deficiencies
0.000 0.820 0.179
E64.3 Sequelae of rickets
0.000 0.820 0.179
E64.2 Sequelae of vitamin C deficiency
0.000 0.820 0.179
E64.1 Sequelae of vitamin A deficiency
0.000 0.820 0.179
E64.0 Sequelae of protein-energy malnutrition
0.000 0.820 0.179
E51.9 Thiamine deficiency, unspecified
0.000 0.822 0.178
E51.8 Other manifestations of thiamine deficiency
0.000 0.822 0.178
E51.1 Beriberi
0.000 0.822 0.178
E51.2 Wernicke's encephalopathy
0.000 0.823 0.176
E53 Deficiency of other B group vitamins
0.000 0.824 0.176
E65 Localised adiposity
0.000 0.829 0.171
E56.9 Vitamin deficiency, unspecified
0.000 0.831 0.169
E56.8 Deficiency of other vitamins
0.000 0.831 0.169
E56.0 Deficiency of vitamin E
0.000 0.831 0.169
E83 Disorders of mineral metabolism
0.143 0.833 0.024
E67.8 Other specified hyperalimentation
0.000 0.835 0.165
E67.3 Hypervitaminosis D
0.000 0.835 0.165
E67.2 Megavitamin-B6 syndrome
0.000 0.835 0.165
E67.1 Hypercarotenaemia
0.000 0.835 0.165
E67.0 Hypervitaminosis A
0.000 0.835 0.165
E55.0 Rickets, active
0.000 0.842 0.158
E20-E35 Disorders of other endocrine glands
0.000 0.843 0.157
E56.1 Deficiency of vitamin K
0.000 0.845 0.155
E06.3 Autoimmune thyroiditis
0.001 0.855 0.144
E61.9 Deficiency of nutrient element, unspecified
0.000 0.855 0.144
E61.8 Deficiency of other specified nutrient elements
0.000 0.855 0.144
E61.7 Deficiency of multiple nutrient elements
0.000 0.855 0.144
E61.6 Vanadium deficiency
0.000 0.855 0.144
E61.5 Molybdenum deficiency
0.000 0.855 0.144
E61.4 Chromium deficiency
0.000 0.855 0.144
E61.3 Manganese deficiency
0.000 0.855 0.144
E61.0 Copper deficiency
0.000 0.855 0.144
E24 Cushing's syndrome
0.000 0.856 0.144
E11.8 With unspecified complications
0.000 0.866 0.134
E53.9 Vitamin B deficiency, unspecified
0.000 0.866 0.134
E14.9 Without complications
0.000 0.868 0.132
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.868 0.132
I83.0 Varicose veins of lower extremities with ulcer
0.131 0.869 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.872 0.127
E61.2 Magnesium deficiency
0.000 0.873 0.127
E83.3 Disorders of phosphorus metabolism
0.121 0.873 0.006
E53.1 Pyridoxine deficiency
0.000 0.874 0.126
E53.0 Riboflavin deficiency
0.000 0.874 0.126
E21.3 Hyperparathyroidism, unspecified
0.000 0.875 0.125
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.124 0.875 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.877 0.123
E61.1 Iron deficiency
0.000 0.880 0.120
E83.8 Other disorders of mineral metabolism
0.102 0.880 0.017
E83.2 Disorders of zinc metabolism
0.102 0.880 0.017
E83.0 Disorders of copper metabolism
0.102 0.880 0.017
E24.0 Pituitary-dependent Cushing's disease
0.000 0.881 0.119
E83.9 Disorder of mineral metabolism, unspecified
0.102 0.881 0.017
E20 Hypoparathyroidism
0.000 0.882 0.117
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.887 0.113
E32 Diseases of thymus
0.000 0.887 0.113
E30 Disorders of puberty, not elsewhere classified
0.000 0.887 0.113
E24.2 Drug-induced Cushing's syndrome
0.000 0.888 0.112
E25 Adrenogenital disorders
0.000 0.891 0.109
E31 Polyglandular dysfunction
0.000 0.892 0.108
M45 Ankylosing spondylitis
0.106 0.894 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.894 0.106
E28 Ovarian dysfunction
0.000 0.896 0.104
E24.8 Other Cushing's syndrome
0.000 0.897 0.103
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.897 0.103
E24.3 Ectopic ACTH syndrome
0.000 0.897 0.103
E24.1 Nelson's syndrome
0.000 0.897 0.103
E29 Testicular dysfunction
0.000 0.898 0.102
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.904 0.096
E21.2 Other hyperparathyroidism
0.000 0.905 0.095
E11.5 With peripheral circulatory complications
0.000 0.905 0.095
E21.4 Other specified disorders of parathyroid gland
0.000 0.905 0.095
E70-E90 Metabolic disorders
0.001 0.909 0.089
E20.9 Hypoparathyroidism, unspecified
0.000 0.911 0.089
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.914 0.086
E20.8 Other hypoparathyroidism
0.000 0.915 0.084
E20.1 Pseudohypoparathyroidism
0.000 0.915 0.084
E20.0 Idiopathic hypoparathyroidism
0.000 0.915 0.084
M45.X2 Ankylosing spondylitis (Cervical region)
0.084 0.916 0.000
E34 Other endocrine disorders
0.000 0.916 0.084
E78.2 Mixed hyperlipidaemia
0.000 0.916 0.084
M45.X6 Ankylosing spondylitis (Lumbar region)
0.082 0.918 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.919 0.081
E30.8 Other disorders of puberty
0.000 0.919 0.081
E30.1 Precocious puberty
0.000 0.919 0.081
E30.0 Delayed puberty
0.000 0.919 0.081
E32.9 Disease of thymus, unspecified
0.000 0.919 0.081
E32.8 Other diseases of thymus
0.000 0.919 0.081
E32.1 Abscess of thymus
0.000 0.919 0.081
E32.0 Persistent hyperplasia of thymus
0.000 0.919 0.081
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.919 0.081
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.919 0.081
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.919 0.081
E25.9 Adrenogenital disorder, unspecified
0.000 0.921 0.078
E25.8 Other adrenogenital disorders
0.000 0.921 0.078
E31.9 Polyglandular dysfunction, unspecified
0.000 0.922 0.077
E31.8 Other polyglandular dysfunction
0.000 0.922 0.077
E31.1 Polyglandular hyperfunction
0.000 0.922 0.077
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.923 0.077
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.076 0.923 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.076 0.923 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.076 0.923 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.076 0.923 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.076 0.923 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.076 0.923 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.924 0.076
E11.3 With ophthalmic complications
0.000 0.924 0.076
E26 Hyperaldosteronism
0.000 0.925 0.075
E78.1 Pure hyperglyceridaemia
0.000 0.925 0.075
E28.9 Ovarian dysfunction, unspecified
0.000 0.925 0.075
E28.8 Other ovarian dysfunction
0.000 0.925 0.075
E28.1 Androgen excess
0.000 0.925 0.075
E28.0 Oestrogen excess
0.000 0.925 0.075
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.925 0.074
E78.5 Hyperlipidaemia, unspecified
0.000 0.925 0.075
E29.9 Testicular dysfunction, unspecified
0.000 0.926 0.074
E29.8 Other testicular dysfunction
0.000 0.927 0.073
E29.0 Testicular hyperfunction
0.000 0.927 0.073
E31.0 Autoimmune polyglandular failure
0.000 0.928 0.072
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.929 0.070
E21.0 Primary hyperparathyroidism
0.000 0.930 0.070
E74 Other disorders of carbohydrate metabolism
0.001 0.931 0.068
E78.6 Lipoprotein deficiency
0.000 0.933 0.067
E73 Lactose intolerance
0.001 0.934 0.065
E85 Amyloidosis
0.001 0.934 0.065
E88 Other metabolic disorders
0.000 0.934 0.065
E77 Disorders of glycoprotein metabolism
0.001 0.935 0.064
E76 Disorders of glycosaminoglycan metabolism
0.001 0.935 0.064
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.935 0.064
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.935 0.064
E78.3 Hyperchylomicronaemia
0.000 0.935 0.065
E28.3 Primary ovarian failure
0.000 0.936 0.064
E84 Cystic fibrosis
0.001 0.936 0.063
I83.1 Varicose veins of lower extremities with inflammation
0.064 0.936 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.063 0.937 0.000
E70 Disorders of aromatic amino-acid metabolism
0.001 0.938 0.061
E34.3 Short stature, not elsewhere classified
0.000 0.938 0.061
E79 Disorders of purine and pyrimidine metabolism
0.001 0.939 0.060
E34.5 Androgen resistance syndrome
0.000 0.939 0.061
E34.4 Constitutional tall stature
0.000 0.939 0.061
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.939 0.061
E34.1 Other hypersecretion of intestinal hormones
0.000 0.939 0.061
E23 Hypofunction and other disorders of pituitary gland
0.000 0.939 0.060
E22 Hyperfunction of pituitary gland
0.000 0.940 0.060
E29.1 Testicular hypofunction
0.000 0.940 0.060
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.940 0.059
E72 Other disorders of amino-acid metabolism
0.001 0.941 0.058
E75.5 Other lipid storage disorders
0.001 0.944 0.056
E34.9 Endocrine disorder, unspecified
0.000 0.945 0.055
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.945 0.055
E78.4 Other hyperlipidaemia
0.000 0.945 0.055
E26.8 Other hyperaldosteronism
0.000 0.946 0.054
E26.1 Secondary hyperaldosteronism
0.000 0.946 0.054
E34.8 Other specified endocrine disorders
0.000 0.946 0.054
E85.4 Organ-limited amyloidosis
0.000 0.946 0.054
E88.9 Metabolic disorder, unspecified
0.000 0.946 0.054
E83.4 Disorders of magnesium metabolism
0.041 0.946 0.012
E23.7 Disorder of pituitary gland, unspecified
0.000 0.948 0.052
E75.2 Other sphingolipidosis
0.001 0.948 0.051
E75.6 Lipid storage disorder, unspecified
0.001 0.949 0.050
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.949 0.050
E75.3 Sphingolipidosis, unspecified
0.001 0.949 0.050
E75.1 Other gangliosidosis
0.001 0.949 0.050
E75.0 GM2 gangliosidosis
0.001 0.949 0.050
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.950 0.050
E34.0 Carcinoid syndrome
0.000 0.950 0.050
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.950 0.049
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.950 0.049
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.950 0.049
E74.2 Disorders of galactose metabolism
0.001 0.950 0.049
E74.1 Disorders of fructose metabolism
0.001 0.950 0.049
E88.2 Lipomatosis, not elsewhere classified
0.000 0.950 0.050
E85.8 Other amyloidosis
0.001 0.950 0.049
E74.0 Glycogen storage disease
0.001 0.952 0.048
E73.9 Lactose intolerance, unspecified
0.000 0.952 0.048
E11.4 With neurological complications
0.000 0.952 0.048
E26.9 Hyperaldosteronism, unspecified
0.000 0.952 0.047
E85.3 Secondary systemic amyloidosis
0.001 0.952 0.047
E73.8 Other lactose intolerance
0.001 0.952 0.047
E73.1 Secondary lactase deficiency
0.001 0.952 0.047
E73.0 Congenital lactase deficiency
0.001 0.952 0.047
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.953 0.047
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.953 0.047
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.953 0.047
C15 Malignant neoplasm of oesophagus
0.000 0.953 0.047
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.953 0.046
E71.3 Disorders of fatty-acid metabolism
0.001 0.953 0.046
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.953 0.046
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.953 0.046
E71.0 Maple-syrup-urine disease
0.001 0.953 0.046
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.953 0.046
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.953 0.046
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.953 0.046
E76.2 Other mucopolysaccharidoses
0.001 0.953 0.046
E76.1 Mucopolysaccharidosis, type II
0.001 0.953 0.046
E76.0 Mucopolysaccharidosis, type I
0.001 0.953 0.046
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.953 0.046
E77.8 Other disorders of glycoprotein metabolism
0.001 0.953 0.046
E77.1 Defects in glycoprotein degradation
0.001 0.953 0.046
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.953 0.046
C15-C26 Malignant neoplasms of digestive organs
0.000 0.954 0.046
E84.8 Cystic fibrosis with other manifestations
0.001 0.954 0.045
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.954 0.045
C20 Malignant neoplasm of rectum
0.000 0.955 0.045
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.955 0.044
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.955 0.044
E70.2 Disorders of tyrosine metabolism
0.001 0.955 0.044
E70.1 Other hyperphenylalaninaemias
0.001 0.955 0.044
E70.0 Classical phenylketonuria
0.001 0.955 0.044
E88.8 Other specified metabolic disorders
0.000 0.956 0.044
E04 Other non-toxic goitre
0.002 0.956 0.042
Z71.8 Other specified counselling
0.044 0.956 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.956 0.043
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.956 0.043
E79.1 Lesch-Nyhan syndrome
0.001 0.956 0.043
E84.9 Cystic fibrosis, unspecified
0.001 0.956 0.043
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.956 0.044
E23.1 Drug-induced hypopituitarism
0.000 0.956 0.044
E22.8 Other hyperfunction of pituitary gland
0.000 0.956 0.043
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.957 0.042
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.957 0.042
E72.5 Disorders of glycine metabolism
0.001 0.957 0.042
E72.4 Disorders of ornithine metabolism
0.001 0.957 0.042
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.957 0.042
E72.2 Disorders of urea cycle metabolism
0.001 0.957 0.042
C15.5 Lower third of oesophagus
0.000 0.957 0.043
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.957 0.042
C15.4 Middle third of oesophagus
0.000 0.958 0.042
E72.0 Disorders of amino-acid transport
0.001 0.958 0.041
E70.3 Albinism
0.001 0.959 0.040
E22.1 Hyperprolactinaemia
0.000 0.959 0.041
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.959 0.041
C15.9 Oesophagus, unspecified
0.000 0.960 0.040
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.960 0.039
E88.3 Tumour lysis syndrome
0.001 0.961 0.038
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.962 0.038
C25 Malignant neoplasm of pancreas
0.000 0.962 0.038
E78.8 Other disorders of lipoprotein metabolism
0.000 0.963 0.037
C15.0 Cervical part of oesophagus
0.000 0.963 0.037
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.964 0.036
C15.3 Upper third of oesophagus
0.000 0.964 0.036
C15.1 Thoracic part of oesophagus
0.000 0.965 0.034
C15.8 Overlapping lesion of oesophagus
0.000 0.966 0.034
C15.2 Abdominal part of oesophagus
0.000 0.966 0.034
C17 Malignant neoplasm of small intestine
0.000 0.966 0.034
E85.9 Amyloidosis, unspecified
0.001 0.967 0.033
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.967 0.033
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.967 0.033
C17.0 Duodenum
0.000 0.967 0.033
C25.1 Body of pancreas
0.000 0.968 0.032
C25.3 Pancreatic duct
0.000 0.968 0.032
E04.8 Other specified non-toxic goitre
0.002 0.968 0.030
C25.2 Tail of pancreas
0.000 0.968 0.032
E26.0 Primary hyperaldosteronism
0.001 0.969 0.030
C25.8 Overlapping lesion of pancreas
0.000 0.970 0.030
E23.2 Diabetes insipidus
0.000 0.970 0.030
C25.4 Endocrine pancreas
0.000 0.970 0.030
E53.8 Deficiency of other specified B group vitamins
0.000 0.971 0.029
E23.6 Other disorders of pituitary gland
0.000 0.971 0.029
C24.0 Extrahepatic bile duct
0.000 0.971 0.029
C21 Malignant neoplasm of anus and anal canal
0.000 0.972 0.028
E80.2 Other porphyria
0.001 0.972 0.027
E22.0 Acromegaly and pituitary gigantism
0.000 0.972 0.027
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.974 0.026
E80.5 Crigler-Najjar syndrome
0.001 0.974 0.026
E80.3 Defects of catalase and peroxydase
0.001 0.974 0.026
E80.0 Hereditary erythropoietic porphyria
0.001 0.974 0.026
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.026 0.974 0.000
R31 Unspecified haematuria
0.026 0.974 0.000
K90-K93 Other diseases of the digestive system
0.000 0.974 0.026
E78.0 Pure hypercholesterolaemia
0.000 0.974 0.026
E66 Obesity
0.000 0.974 0.025
C25.7 Other parts of pancreas
0.000 0.975 0.025
C25.9 Pancreas, unspecified
0.000 0.975 0.025
C17.8 Overlapping lesion of small intestine
0.000 0.975 0.024
C17.3 Meckel's diverticulum
0.000 0.975 0.024
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.025 0.975 0.000
C24.8 Overlapping lesion of biliary tract
0.000 0.976 0.024
E80.1 Porphyria cutanea tarda
0.001 0.977 0.022
I89.0 Lymphoedema, not elsewhere classified
0.023 0.977 0.000
E83.5 Disorders of calcium metabolism
0.005 0.977 0.018
E04.0 Non-toxic diffuse goitre
0.002 0.977 0.021
C24.9 Biliary tract, unspecified
0.000 0.978 0.022
E80.6 Other disorders of bilirubin metabolism
0.001 0.978 0.022
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.022 0.978 0.000
I86 Varicose veins of other sites
0.022 0.978 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.978 0.022
C17.1 Jejunum
0.000 0.978 0.022
M45-M49 Spondylopathies
0.022 0.978 0.000
Z72.0 Tobacco use
0.021 0.979 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.979 0.021
C21.2 Cloacogenic zone
0.000 0.980 0.020
C23 Malignant neoplasm of gallbladder
0.000 0.980 0.020
E11.9 Without complications
0.000 0.980 0.020
I81 Portal vein thrombosis
0.020 0.980 0.000
I86.8 Varicose veins of other specified sites
0.020 0.980 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.981 0.019
I89.1 Lymphangitis
0.019 0.981 0.000
E66.1 Drug-induced obesity
0.000 0.981 0.018
I86.4 Gastric varices
0.018 0.981 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.982 0.018
I82 Other venous embolism and thrombosis
0.018 0.982 0.000
E23.0 Hypopituitarism
0.000 0.982 0.018
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.982 0.018
E27 Other disorders of adrenal gland
0.000 0.982 0.017
C21.0 Anus, unspecified
0.000 0.983 0.017
I85 Oesophageal varices
0.017 0.983 0.000
M49 Spondylopathies in diseases classified elsewhere
0.017 0.983 0.000
I86.3 Vulval varices
0.017 0.983 0.000
I86.2 Pelvic varices
0.017 0.983 0.000
C21.1 Anal canal
0.000 0.984 0.016
C17.9 Small intestine, unspecified
0.000 0.984 0.016
I87 Other disorders of veins
0.016 0.984 0.000
I86.0 Sublingual varices
0.016 0.984 0.000
C17.2 Ileum
0.000 0.984 0.016
I88 Nonspecific lymphadenitis
0.015 0.984 0.000
I82.8 Embolism and thrombosis of other specified veins
0.015 0.985 0.000
C26.8 Overlapping lesion of digestive system
0.000 0.985 0.015
C26.1 Spleen
0.000 0.985 0.015
E66.0 Obesity due to excess calories
0.000 0.985 0.015
M46 Other inflammatory spondylopathies
0.015 0.985 0.000
I82.0 Budd-Chiari syndrome
0.014 0.986 0.000
S02.4 Fracture of malar and maxillary bones
0.000 0.986 0.014
C24.1 Ampulla of Vater
0.000 0.986 0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.986 0.014
K93.1 Megacolon in Chagas' disease
0.000 0.986 0.014
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.986 0.014
M46.9 Inflammatory spondylopathy, unspecified
0.014 0.986 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.014 0.986 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.986 0.013
C22.7 Other specified carcinomas of liver
0.000 0.986 0.013
C22.4 Other sarcomas of liver
0.000 0.986 0.013
C22.3 Angiosarcoma of liver
0.000 0.986 0.013
C22.2 Hepatoblastoma
0.000 0.986 0.013
I82.1 Thrombophlebitis migrans
0.013 0.987 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.013 0.987 0.000
C22.9 Liver, unspecified
0.000 0.987 0.013
I85.9 Oesophageal varices without bleeding
0.013 0.987 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.013 0.987 0.000
I87.8 Other specified disorders of veins
0.013 0.987 0.000
M47.1 Other spondylosis with myelopathy
0.013 0.987 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.987 0.013
E27.0 Other adrenocortical overactivity
0.000 0.987 0.013
I82.3 Embolism and thrombosis of renal vein
0.013 0.987 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.012 0.988 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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