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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129948
log Bayes Factor = 179.013
Chromosome 6   position 32,354,644  (GRCh37) Explore rs3129948 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.001 0.999
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.001 0.999
J30-J39 Other diseases of upper respiratory tract
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
L40 Psoriasis
0.000 0.002 0.998
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.003 0.997
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
L40-L45 Papulosquamous disorders
0.000 0.003 0.997
Chapter X Diseases of the respiratory system
0.000 0.005 0.995
# Top node
0.000 0.005 0.995
J40-J47 Chronic lower respiratory diseases
0.000 0.006 0.994
J33.8 Other polyp of sinus
0.000 0.007 0.993
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.008 0.992
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.008 0.992
L40.5 Arthropathic psoriasis
0.000 0.009 0.991
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.012 0.988
J32 Chronic sinusitis
0.000 0.014 0.986
G35-G37 Demyelinating diseases of the central nervous system
0.984 0.016 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.017 0.983
E10.5 With peripheral circulatory complications
0.000 0.017 0.983
J43 Emphysema
0.000 0.018 0.982
H36 Retinal disorders in diseases classified elsewhere
0.000 0.019 0.981
G37 Other demyelinating diseases of central nervous system
0.981 0.019 0.000
E14.9 Without complications
0.000 0.019 0.981
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.022 0.978
G37.9 Demyelinating disease of central nervous system, unspecified
0.977 0.023 0.000
J32.9 Chronic sinusitis, unspecified
0.000 0.029 0.971
M20-M25 Other joint disorders
0.000 0.029 0.971
Chapter VII Diseases of the eye and adnexa
0.000 0.030 0.970
L43 Lichen planus
0.000 0.031 0.969
J46 Status asthmaticus
0.000 0.031 0.969
J43.9 Emphysema, unspecified
0.000 0.031 0.969
M35.3 Polymyalgia rheumatica
0.000 0.031 0.969
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.032 0.968
H30-H36 Disorders of choroid and retina
0.000 0.032 0.968
M35 Other systemic involvement of connective tissue
0.000 0.032 0.968
E10.2 With renal complications
0.000 0.033 0.967
M06.3 Rheumatoid nodule
0.000 0.035 0.965
M25.46 Effusion of joint (Lower leg)
0.000 0.037 0.963
M06.0 Seronegative rheumatoid arthritis
0.000 0.041 0.959
M25.4 Effusion of joint
0.000 0.042 0.958
Chapter VIII Diseases of the ear and mastoid process
0.000 0.042 0.958
M25 Other joint disorders, not elsewhere classified
0.000 0.045 0.955
J38.3 Other diseases of vocal cords
0.000 0.049 0.951
J44 Other chronic obstructive pulmonary disease
0.000 0.050 0.950
L43.9 Lichen planus, unspecified
0.000 0.050 0.950
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.052 0.948
H43-H45 Disorders of vitreous body and globe
0.000 0.055 0.945
H25-H28 Disorders of lens
0.000 0.066 0.934
H60-H62 Diseases of external ear
0.000 0.071 0.929
M65-M68 Disorders of synovium and tendon
0.000 0.074 0.926
H43 Disorders of vitreous body
0.000 0.074 0.926
J38.0 Paralysis of vocal cords and larynx
0.000 0.076 0.924
K90 Intestinal malabsorption
0.000 0.082 0.918
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.084 0.916
E10.0 With coma
0.000 0.084 0.916
E11.1 With ketoacidosis
0.000 0.087 0.913
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.088 0.912
E10.8 With unspecified complications
0.000 0.089 0.911
H90-H95 Other disorders of ear
0.000 0.093 0.907
M07 Psoriatic and enteropathic arthropathies
0.000 0.097 0.903
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.099 0.901
M65 Synovitis and tenosynovitis
0.000 0.099 0.901
M06.34 Rheumatoid nodule (Hand)
0.000 0.101 0.899
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.101 0.899
K90-K93 Other diseases of the digestive system
0.000 0.102 0.898
E06 Thyroiditis
0.000 0.103 0.897
H91 Other hearing loss
0.000 0.103 0.897
Chapter XI Diseases of the digestive system
0.000 0.105 0.895
E10.6 With other specified complications
0.000 0.106 0.894
H27 Other disorders of lens
0.000 0.107 0.893
M31 Other necrotising vasculopathies
0.000 0.107 0.893
H91.9 Hearing loss, unspecified
0.000 0.111 0.889
H25.1 Senile nuclear cataract
0.000 0.114 0.886
E11.3 With ophthalmic complications
0.000 0.115 0.885
H25 Senile cataract
0.000 0.115 0.885
H60 Otitis externa
0.000 0.120 0.880
M31.6 Other giant cell arteritis
0.000 0.122 0.878
E40-E46 Malnutrition
0.000 0.124 0.876
K70-K77 Diseases of liver
0.000 0.125 0.875
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.146 0.854
L40.0 Psoriasis vulgaris
0.000 0.146 0.854
K74 Fibrosis and cirrhosis of liver
0.000 0.147 0.853
E06.3 Autoimmune thyroiditis
0.000 0.150 0.850
E13 Other specified diabetes mellitus
0.000 0.151 0.849
H43.3 Other vitreous opacities
0.000 0.152 0.848
K74.3 Primary biliary cirrhosis
0.000 0.152 0.848
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.153 0.847
G37.8 Other specified demyelinating diseases of central nervous system
0.845 0.155 0.000
E11.5 With peripheral circulatory complications
0.000 0.158 0.842
J32.4 Chronic pansinusitis
0.000 0.159 0.841
H27.0 Aphakia
0.000 0.160 0.840
M07.3 Other psoriatic arthropathies
0.000 0.167 0.833
E03.8 Other specified hypothyroidism
0.000 0.172 0.828
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.173 0.827
K73 Chronic hepatitis, not elsewhere classified
0.000 0.176 0.824
H61 Other disorders of external ear
0.000 0.178 0.822
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.179 0.821
M06.4 Inflammatory polyarthropathy
0.000 0.182 0.818
K50-K52 Noninfective enteritis and colitis
0.013 0.184 0.803
H43.1 Vitreous haemorrhage
0.000 0.186 0.814
J37 Chronic laryngitis and laryngotracheitis
0.000 0.187 0.813
E07 Other disorders of thyroid
0.000 0.189 0.811
E14.8 With unspecified complications
0.000 0.189 0.811
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.190 0.810
M25.6 Stiffness of joint, not elsewhere classified
0.000 0.191 0.809
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.192 0.808
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.194 0.806
E11.8 With unspecified complications
0.000 0.194 0.806
J33.0 Polyp of nasal cavity
0.000 0.194 0.806
M35.1 Other overlap syndromes
0.000 0.195 0.805
J38.1 Polyp of vocal cord and larynx
0.000 0.197 0.803
H43.8 Other disorders of vitreous body
0.000 0.200 0.800
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.201 0.799
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.203 0.797
H27.8 Other specified disorders of lens
0.000 0.207 0.793
J38.6 Stenosis of larynx
0.000 0.211 0.789
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.211 0.789
J32.2 Chronic ethmoidal sinusitis
0.000 0.211 0.789
K50 Crohn's disease [regional enteritis]
0.000 0.213 0.786
E46 Unspecified protein-energy malnutrition
0.000 0.214 0.786
E14.5 With peripheral circulatory complications
0.000 0.214 0.786
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.216 0.784
E11.0 With coma
0.000 0.219 0.781
M25.40 Effusion of joint (Multiple sites)
0.000 0.220 0.780
M34 Systemic sclerosis
0.000 0.222 0.778
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.228 0.772
E14.1 With ketoacidosis
0.000 0.228 0.772
J33.1 Polypoid sinus degeneration
0.000 0.229 0.771
C83.3 Large cell (diffuse)
0.000 0.230 0.770
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.230 0.769
J43.2 Centrilobular emphysema
0.000 0.231 0.769
E16.1 Other hypoglycaemia
0.000 0.232 0.768
H30 Chorioretinal inflammation
0.000 0.232 0.768
E11.2 With renal complications
0.000 0.233 0.767
J86 Pyothorax
0.000 0.236 0.764
H40-H42 Glaucoma
0.000 0.238 0.762
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.238 0.761
J38.4 Oedema of larynx
0.000 0.240 0.760
M14 Arthropathies in other diseases classified elsewhere
0.000 0.241 0.759
K51.9 Ulcerative colitis, unspecified
0.758 0.242 0.000
K50.8 Other Crohn's disease
0.000 0.244 0.756
J45 Asthma
0.000 0.249 0.751
H60.3 Other infective otitis externa
0.000 0.251 0.749
M25.43 Effusion of joint (Forearm)
0.000 0.254 0.746
J41 Simple and mucopurulent chronic bronchitis
0.000 0.256 0.744
J43.8 Other emphysema
0.000 0.256 0.743
E11.6 With other specified complications
0.000 0.260 0.740
E13.9 Without complications
0.000 0.260 0.740
M60-M63 Disorders of muscles
0.000 0.261 0.739
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.262 0.738
K51 Ulcerative colitis
0.736 0.263 0.001
H60.5 Acute otitis externa, non-infective
0.000 0.264 0.736
K73.9 Chronic hepatitis, unspecified
0.000 0.264 0.736
H60.4 Cholesteatoma of external ear
0.000 0.265 0.735
H60.1 Cellulitis of external ear
0.000 0.266 0.734
M65.8 Other synovitis and tenosynovitis
0.000 0.267 0.733
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.268 0.732
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.274 0.726
J32.8 Other chronic sinusitis
0.000 0.275 0.725
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.275 0.725
M10 Gout
0.000 0.275 0.725
H43.2 Crystalline deposits in vitreous body
0.000 0.276 0.724
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.276 0.724
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.276 0.724
H61.8 Other specified disorders of external ear
0.000 0.277 0.723
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.278 0.722
E14.4 With neurological complications
0.000 0.278 0.722
M25.0 Haemarthrosis
0.000 0.280 0.720
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.282 0.718
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
K51.3 Ulcerative (chronic) rectosigmoiditis
0.716 0.284 0.000
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.285 0.714
L41 Parapsoriasis
0.000 0.285 0.714
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.285 0.714
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.287 0.713
L50-L54 Urticaria and erythema
0.000 0.288 0.712
H91.1 Presbycusis
0.000 0.289 0.711
M25.42 Effusion of joint (Upper arm)
0.000 0.289 0.710
K50.1 Crohn's disease of large intestine
0.000 0.291 0.709
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.294 0.705
L10-L14 Bullous disorders
0.000 0.295 0.705
J43.1 Panlobular emphysema
0.000 0.296 0.704
J43.0 MacLeod's syndrome
0.000 0.296 0.704
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.296 0.704
G37.5 Concentric sclerosis [Balo]
0.703 0.297 0.000
G37.4 Subacute necrotising myelitis
0.703 0.297 0.000
G37.2 Central pontine myelinolysis
0.703 0.297 0.000
G37.1 Central demyelination of corpus callosum
0.703 0.297 0.000
G37.0 Diffuse sclerosis
0.703 0.297 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.300 0.700
M31.9 Necrotising vasculopathy, unspecified
0.000 0.301 0.699
L43.8 Other lichen planus
0.000 0.301 0.699
M12 Other specific arthropathies
0.000 0.302 0.698
L40.1 Generalised pustular psoriasis
0.000 0.302 0.698
E07.9 Disorder of thyroid, unspecified
0.000 0.304 0.696
L43.3 Subacute (active) lichen planus
0.000 0.305 0.695
L43.2 Lichenoid drug reaction
0.000 0.305 0.695
L43.1 Bullous lichen planus
0.000 0.305 0.695
L43.0 Hypertrophic lichen planus
0.000 0.305 0.695
L40.3 Pustulosis palmaris et plantaris
0.000 0.305 0.695
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.306 0.694
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.306 0.694
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.306 0.694
M35.5 Multifocal fibrosclerosis
0.000 0.306 0.694
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.306 0.694
H44 Disorders of globe
0.000 0.306 0.694
M25.45 Effusion of joint (Pelvic region and thigh)
0.000 0.307 0.693
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.308 0.692
M06.38 Rheumatoid nodule (Other)
0.000 0.308 0.692
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.308 0.692
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.308 0.692
M06.33 Rheumatoid nodule (Forearm)
0.000 0.308 0.692
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.308 0.692
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.308 0.692
M06.8 Other specified rheumatoid arthritis
0.000 0.308 0.692
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.310 0.690
J45.9 Asthma, unspecified
0.000 0.310 0.690
J32.1 Chronic frontal sinusitis
0.000 0.310 0.689
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.312 0.688
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.312 0.688
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.312 0.688
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.312 0.688
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.312 0.688
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.312 0.688
M25.49 Effusion of joint (Site unspecified)
0.000 0.313 0.687
M25.48 Effusion of joint (Other)
0.000 0.313 0.687
H61.3 Acquired stenosis of external ear canal
0.000 0.313 0.687
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.313 0.687
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.686 0.314 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.000 0.314 0.686
M25.2 Flail joint
0.000 0.315 0.685
M25.1 Fistula of joint
0.000 0.315 0.685
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.316 0.684
E11.4 With neurological complications
0.000 0.317 0.683
E03.1 Congenital hypothyroidism without goitre
0.000 0.318 0.682
J37.0 Chronic laryngitis
0.000 0.320 0.680
G36 Other acute disseminated demyelination
0.678 0.322 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.322 0.678
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.000 0.327 0.673
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.328 0.672
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.328 0.672
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.329 0.671
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.330 0.670
H91.2 Sudden idiopathic hearing loss
0.000 0.331 0.669
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.331 0.669
C82.0 Small cleaved cell, follicular
0.000 0.331 0.669
M66 Spontaneous rupture of synovium and tendon
0.000 0.332 0.668
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.334 0.666
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.336 0.664
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.336 0.664
H43.0 Vitreous prolapse
0.000 0.336 0.664
H34 Retinal vascular occlusions
0.000 0.337 0.663
J86.0 Pyothorax with fistula
0.000 0.338 0.662
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.339 0.661
M25.41 Effusion of joint (Shoulder region)
0.000 0.342 0.658
K90.3 Pancreatic steatorrhoea
0.000 0.342 0.658
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.342 0.658
K90.1 Tropical sprue
0.000 0.342 0.658
C91 Lymphoid leukaemia
0.000 0.343 0.657
K75 Other inflammatory liver diseases
0.000 0.345 0.655
M60 Myositis
0.000 0.345 0.654
M30 Polyarteritis nodosa and related conditions
0.000 0.347 0.653
K76 Other diseases of liver
0.000 0.348 0.652
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.349 0.650
K50.0 Crohn's disease of small intestine
0.000 0.350 0.650
H61.1 Non-infective disorders of pinna
0.000 0.351 0.649
C85.1 B-cell lymphoma, unspecified
0.000 0.352 0.648
M07.6 Other enteropathic arthropathies
0.000 0.353 0.647
M07.5 Arthropathy in ulcerative colitis
0.000 0.353 0.647
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.353 0.647
M07.2 Psoriatic spondylitis
0.000 0.353 0.647
M07.1 Arthritis mutilans
0.000 0.353 0.647
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.353 0.647
M65.2 Calcific tendinitis
0.000 0.354 0.646
M65.0 Abscess of tendon sheath
0.000 0.354 0.646
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.356 0.644
E06.5 Other chronic thyroiditis
0.000 0.357 0.643
E06.4 Drug-induced thyroiditis
0.000 0.357 0.643
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.357 0.643
E06.0 Acute thyroiditis
0.000 0.357 0.643
H91.0 Ototoxic hearing loss
0.000 0.357 0.643
K51.8 Other ulcerative colitis
0.642 0.358 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.360 0.640
H27.9 Disorder of lens, unspecified
0.000 0.360 0.640
M31.8 Other specified necrotising vasculopathies
0.000 0.360 0.640
M31.7 Microscopic polyangiitis
0.000 0.360 0.640
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.360 0.640
M31.2 Lethal midline granuloma
0.000 0.360 0.640
K76.8 Other specified diseases of liver
0.000 0.360 0.640
K90.9 Intestinal malabsorption, unspecified
0.000 0.361 0.639
J86.9 Pyothorax without fistula
0.000 0.361 0.639
C82.2 Large cell, follicular
0.000 0.364 0.635
H25.2 Senile cataract, morgagnian type
0.000 0.365 0.635
D86.0 Sarcoidosis of lung
0.634 0.366 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.367 0.633
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.367 0.633
H43.9 Disorder of vitreous body, unspecified
0.000 0.367 0.633
H60.2 Malignant otitis externa
0.000 0.369 0.631
H60.0 Abscess of external ear
0.000 0.371 0.629
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.372 0.628
E45 Retarded development following protein-energy malnutrition
0.000 0.372 0.628
E43 Unspecified severe protein-energy malnutrition
0.000 0.372 0.628
E42 Marasmic kwashiorkor
0.000 0.372 0.628
E41 Nutritional marasmus
0.000 0.372 0.628
E40 Kwashiorkor
0.000 0.372 0.628
K77 Liver disorders in diseases classified elsewhere
0.000 0.372 0.628
J32.0 Chronic maxillary sinusitis
0.000 0.373 0.627
M05.2 Rheumatoid vasculitis
0.000 0.373 0.626
K72 Hepatic failure, not elsewhere classified
0.000 0.375 0.625
H30.9 Chorioretinal inflammation, unspecified
0.000 0.376 0.624
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.000 0.376 0.623
C82.3 Follicular lymphoma grade IIIa
0.000 0.377 0.623
M35.8 Other specified systemic involvement of connective tissue
0.000 0.378 0.622
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.380 0.620
M34.1 CR(E)ST syndrome
0.000 0.381 0.619
M14.6 Neuropathic arthropathy
0.000 0.381 0.619
C95 Leukaemia of unspecified cell type
0.000 0.384 0.616
M65.1 Other infective (teno)synovitis
0.000 0.386 0.614
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.388 0.612
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.388 0.612
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.388 0.612
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.388 0.612
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.388 0.612
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.388 0.612
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.388 0.612
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.388 0.612
H40 Glaucoma
0.000 0.388 0.612
K74.4 Secondary biliary cirrhosis
0.000 0.388 0.612
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.388 0.612
K74.1 Hepatic sclerosis
0.000 0.388 0.612
M00-M03 Infectious arthropathies
0.000 0.388 0.612
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.388 0.612
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.389 0.611
H91.3 Deaf mutism, not elsewhere classified
0.000 0.389 0.610
M25.47 Effusion of joint (Ankle and foot)
0.000 0.390 0.610
M35.7 Hypermobility syndrome
0.000 0.390 0.610
M35.2 Behcet's disease
0.000 0.391 0.609
E13.8 With unspecified complications
0.000 0.392 0.608
E13.7 With multiple complications
0.000 0.392 0.608
E13.6 With other specified complications
0.000 0.392 0.608
E13.5 With peripheral circulatory complications
0.000 0.392 0.608
E13.4 With neurological complications
0.000 0.392 0.608
E13.3 With ophthalmic complications
0.000 0.392 0.608
E13.2 With renal complications
0.000 0.392 0.608
E13.1 With ketoacidosis
0.000 0.392 0.608
E13.0 With coma
0.000 0.392 0.608
Chapter II Neoplasms
0.000 0.392 0.608
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.393 0.607
L51 Erythema multiforme
0.000 0.394 0.606
C91.1 Chronic lymphocytic leukaemia
0.000 0.394 0.606
K51.5 Mucosal proctocolitis
0.605 0.395 0.001
J38.5 Laryngeal spasm
0.000 0.395 0.604
K75.4 Autoimmune hepatitis
0.000 0.396 0.604
L03 Cellulitis
0.000 0.397 0.603
H44.0 Purulent endophthalmitis
0.000 0.397 0.603
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.000 0.398 0.602
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.000 0.400 0.600
L03.0 Cellulitis of finger and toe
0.000 0.400 0.600
J42 Unspecified chronic bronchitis
0.000 0.400 0.600
M34.8 Other forms of systemic sclerosis
0.000 0.400 0.599
J32.3 Chronic sphenoidal sinusitis
0.000 0.401 0.599
C82.4 Follicular lymphoma grade IIIb
0.000 0.402 0.598
H40.9 Glaucoma, unspecified
0.000 0.403 0.597
M07.38 Other psoriatic arthropathies (Other)
0.000 0.403 0.597
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.403 0.597
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.403 0.597
H61.2 Impacted cerumen
0.000 0.403 0.597
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.405 0.595
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.406 0.594
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.407 0.593
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.407 0.593
H60.9 Otitis externa, unspecified
0.000 0.408 0.592
H61.0 Perichondritis of external ear
0.000 0.408 0.592
M60.0 Infective myositis
0.000 0.409 0.591
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.409 0.591
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.409 0.591
J39 Other diseases of upper respiratory tract
0.000 0.409 0.591
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.000 0.410 0.590
D86 Sarcoidosis
0.589 0.410 0.001
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.411 0.589
K74.5 Biliary cirrhosis, unspecified
0.000 0.412 0.588
H92 Otalgia and effusion of ear
0.000 0.413 0.587
M25.9 Joint disorder, unspecified
0.000 0.413 0.587
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.413 0.586
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.413 0.586
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.413 0.586
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.413 0.586
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.413 0.586
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.413 0.586
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.413 0.586
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.413 0.586
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.414 0.586
H95.1 Other disorders following mastoidectomy
0.000 0.414 0.586
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.415 0.585
L52 Erythema nodosum
0.000 0.416 0.584
E06.9 Thyroiditis, unspecified
0.000 0.416 0.584
J37.1 Chronic laryngotracheitis
0.000 0.417 0.583
E07.1 Dyshormogenetic goitre
0.000 0.418 0.582
E07.0 Hypersecretion of calcitonin
0.000 0.418 0.582
M25.3 Other instability of joint
0.000 0.419 0.581
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.419 0.581
K71 Toxic liver disease
0.000 0.420 0.580
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.000 0.420 0.580
H60.8 Other otitis externa
0.000 0.421 0.579
C82.6 Cutaneous follicle centre lymphoma
0.000 0.422 0.578
C82.5 Diffuse follicle centre lymphoma
0.000 0.422 0.578
M10.9 Gout, unspecified
0.000 0.422 0.578
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.427 0.573
C83.1 Small cleaved cell (diffuse)
0.000 0.427 0.573
M31.1 Thrombotic microangiopathy
0.000 0.429 0.571
E06.1 Subacute thyroiditis
0.000 0.432 0.568
H91.8 Other specified hearing loss
0.000 0.432 0.568
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.000 0.432 0.568
J41.0 Simple chronic bronchitis
0.000 0.434 0.566
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.435 0.565
L42 Pityriasis rosea
0.000 0.436 0.564
M33 Dermatopolymyositis
0.000 0.436 0.564
H40.5 Glaucoma secondary to other eye disorders
0.000 0.436 0.564
M25.44 Effusion of joint (Hand)
0.000 0.440 0.559
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.440 0.559
D86.9 Sarcoidosis, unspecified
0.560 0.440 0.000
H34.1 Central retinal artery occlusion
0.000 0.441 0.559
J45.1 Nonallergic asthma
0.000 0.441 0.559
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.442 0.558
M34.0 Progressive systemic sclerosis
0.000 0.442 0.558
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.444 0.556
C45 Mesothelioma
0.000 0.444 0.556
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.444 0.556
L13 Other bullous disorders
0.000 0.445 0.555
K51.4 Pseudopolyposis of colon
0.554 0.445 0.001
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.446 0.554
M25.06 Haemarthrosis (Lower leg)
0.000 0.448 0.552
H30.8 Other chorioretinal inflammations
0.000 0.450 0.550
H30.2 Posterior cyclitis
0.000 0.450 0.550
H30.1 Disseminated chorioretinal inflammation
0.000 0.450 0.550

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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