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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129952
log Bayes Factor = 176.543
Chromosome 6   position 32,359,763  (GRCh37) Explore rs3129952 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.001 0.999
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.001 0.999
J33 Nasal polyp
0.000 0.003 0.997
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.003 0.997
J33.9 Nasal polyp, unspecified
0.000 0.005 0.995
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
J30-J39 Other diseases of upper respiratory tract
0.000 0.009 0.991
L40 Psoriasis
0.000 0.010 0.990
L40.9 Psoriasis, unspecified
0.000 0.011 0.989
J33.8 Other polyp of sinus
0.000 0.012 0.988
L40.5 Arthropathic psoriasis
0.000 0.016 0.984
E14.9 Without complications
0.000 0.017 0.983
E10.5 With peripheral circulatory complications
0.000 0.017 0.983
J32 Chronic sinusitis
0.000 0.019 0.981
L40-L45 Papulosquamous disorders
0.000 0.019 0.981
G35-G37 Demyelinating diseases of the central nervous system
0.977 0.023 0.000
G37 Other demyelinating diseases of central nervous system
0.972 0.027 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.029 0.971
J32.9 Chronic sinusitis, unspecified
0.000 0.029 0.971
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.029 0.971
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.030 0.970
M06.3 Rheumatoid nodule
0.000 0.032 0.968
G37.9 Demyelinating disease of central nervous system, unspecified
0.966 0.034 0.000
E10.2 With renal complications
0.000 0.034 0.966
M06.0 Seronegative rheumatoid arthritis
0.000 0.039 0.961
J40-J47 Chronic lower respiratory diseases
0.000 0.042 0.958
Chapter X Diseases of the respiratory system
0.000 0.042 0.958
# Top node
0.000 0.049 0.951
H36 Retinal disorders in diseases classified elsewhere
0.000 0.051 0.949
J43 Emphysema
0.000 0.051 0.949
L43 Lichen planus
0.000 0.052 0.948
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.056 0.944
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.059 0.941
J43.9 Emphysema, unspecified
0.000 0.060 0.940
J46 Status asthmaticus
0.000 0.066 0.934
J38.3 Other diseases of vocal cords
0.000 0.068 0.932
J44 Other chronic obstructive pulmonary disease
0.000 0.071 0.929
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.071 0.929
L43.9 Lichen planus, unspecified
0.000 0.075 0.925
M07 Psoriatic and enteropathic arthropathies
0.000 0.079 0.921
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.083 0.917
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.084 0.916
E10.0 With coma
0.000 0.084 0.916
Chapter VII Diseases of the eye and adnexa
0.000 0.086 0.914
H30-H36 Disorders of choroid and retina
0.000 0.087 0.913
E11.1 With ketoacidosis
0.000 0.088 0.912
M25.46 Effusion of joint (Lower leg)
0.000 0.088 0.912
E10.8 With unspecified complications
0.000 0.090 0.910
Chapter VIII Diseases of the ear and mastoid process
0.000 0.090 0.910
M06.34 Rheumatoid nodule (Hand)
0.000 0.094 0.906
J38.0 Paralysis of vocal cords and larynx
0.000 0.094 0.906
E06 Thyroiditis
0.000 0.099 0.901
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.099 0.901
M35.3 Polymyalgia rheumatica
0.000 0.099 0.901
M20-M25 Other joint disorders
0.000 0.101 0.899
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.101 0.899
M35 Other systemic involvement of connective tissue
0.000 0.103 0.897
M25.4 Effusion of joint
0.000 0.104 0.896
E10.6 With other specified complications
0.000 0.106 0.894
E11.3 With ophthalmic complications
0.000 0.111 0.889
H60-H62 Diseases of external ear
0.000 0.114 0.886
H25-H28 Disorders of lens
0.000 0.114 0.886
M25 Other joint disorders, not elsewhere classified
0.000 0.115 0.885
H43-H45 Disorders of vitreous body and globe
0.000 0.122 0.878
E40-E46 Malnutrition
0.000 0.126 0.874
M07.3 Other psoriatic arthropathies
0.000 0.129 0.871
H27 Other disorders of lens
0.000 0.142 0.858
H90-H95 Other disorders of ear
0.000 0.149 0.851
H43 Disorders of vitreous body
0.000 0.149 0.851
E06.3 Autoimmune thyroiditis
0.000 0.154 0.846
K90 Intestinal malabsorption
0.000 0.159 0.841
H91 Other hearing loss
0.000 0.160 0.840
G37.8 Other specified demyelinating diseases of central nervous system
0.838 0.162 0.000
H60 Otitis externa
0.000 0.163 0.837
J32.4 Chronic pansinusitis
0.000 0.163 0.837
M65-M68 Disorders of synovium and tendon
0.000 0.164 0.836
H25.1 Senile nuclear cataract
0.000 0.166 0.834
H25 Senile cataract
0.000 0.168 0.832
H91.9 Hearing loss, unspecified
0.000 0.168 0.832
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.169 0.831
J33.0 Polyp of nasal cavity
0.000 0.170 0.830
E13 Other specified diabetes mellitus
0.000 0.170 0.830
L40.0 Psoriasis vulgaris
0.000 0.174 0.826
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.179 0.821
E11.5 With peripheral circulatory complications
0.000 0.180 0.820
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.182 0.818
M06.4 Inflammatory polyarthropathy
0.000 0.183 0.817
E07 Other disorders of thyroid
0.000 0.184 0.816
J37 Chronic laryngitis and laryngotracheitis
0.000 0.184 0.816
H27.0 Aphakia
0.000 0.189 0.811
E14.8 With unspecified complications
0.000 0.189 0.811
J38.1 Polyp of vocal cord and larynx
0.000 0.191 0.809
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.192 0.808
K90-K93 Other diseases of the digestive system
0.000 0.195 0.805
E11.8 With unspecified complications
0.000 0.195 0.805
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.200 0.800
Chapter XI Diseases of the digestive system
0.000 0.201 0.799
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.201 0.799
H61 Other disorders of external ear
0.000 0.202 0.798
E03.8 Other specified hypothyroidism
0.000 0.207 0.793
M65 Synovitis and tenosynovitis
0.000 0.208 0.792
M31 Other necrotising vasculopathies
0.000 0.213 0.787
E14.5 With peripheral circulatory complications
0.000 0.215 0.785
E46 Unspecified protein-energy malnutrition
0.000 0.216 0.784
J32.2 Chronic ethmoidal sinusitis
0.000 0.216 0.784
K70-K77 Diseases of liver
0.000 0.217 0.783
H27.8 Other specified disorders of lens
0.000 0.219 0.781
J38.6 Stenosis of larynx
0.000 0.221 0.779
H43.3 Other vitreous opacities
0.000 0.228 0.772
E14.1 With ketoacidosis
0.000 0.228 0.772
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.231 0.769
J33.1 Polypoid sinus degeneration
0.000 0.232 0.768
M31.6 Other giant cell arteritis
0.000 0.232 0.768
E16.1 Other hypoglycaemia
0.000 0.232 0.767
E11.0 With coma
0.000 0.233 0.767
K74 Fibrosis and cirrhosis of liver
0.000 0.241 0.759
M14 Arthropathies in other diseases classified elsewhere
0.000 0.242 0.758
K74.3 Primary biliary cirrhosis
0.000 0.245 0.755
E11.2 With renal complications
0.000 0.248 0.752
J38.4 Oedema of larynx
0.000 0.252 0.748
M35.1 Other overlap syndromes
0.000 0.255 0.745
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.255 0.745
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.260 0.740
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.260 0.740
J86 Pyothorax
0.000 0.260 0.740
E11.6 With other specified complications
0.000 0.261 0.739
M10 Gout
0.000 0.262 0.738
E14.4 With neurological complications
0.000 0.265 0.735
K73 Chronic hepatitis, not elsewhere classified
0.000 0.267 0.733
J32.8 Other chronic sinusitis
0.000 0.268 0.732
J43.2 Centrilobular emphysema
0.000 0.270 0.730
M25.40 Effusion of joint (Multiple sites)
0.000 0.271 0.729
H43.1 Vitreous haemorrhage
0.000 0.275 0.725
H30 Chorioretinal inflammation
0.000 0.276 0.724
M25.6 Stiffness of joint, not elsewhere classified
0.000 0.280 0.720
K51.9 Ulcerative colitis, unspecified
0.719 0.281 0.000
J43.8 Other emphysema
0.000 0.281 0.719
M34 Systemic sclerosis
0.000 0.282 0.718
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.282 0.718
J41 Simple and mucopurulent chronic bronchitis
0.000 0.282 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
H43.8 Other disorders of vitreous body
0.000 0.284 0.716
M60-M63 Disorders of muscles
0.000 0.287 0.713
H60.3 Other infective otitis externa
0.000 0.287 0.713
L40.4 Guttate psoriasis
0.000 0.290 0.710
L40.2 Acrodermatitis continua
0.000 0.290 0.710
H60.5 Acute otitis externa, non-infective
0.000 0.291 0.709
E13.9 Without complications
0.000 0.292 0.708
H61.8 Other specified disorders of external ear
0.000 0.293 0.707
K50-K52 Noninfective enteritis and colitis
0.019 0.296 0.685
E07.9 Disorder of thyroid, unspecified
0.000 0.297 0.703
L44 Other papulosquamous disorders
0.000 0.297 0.703
L41 Parapsoriasis
0.000 0.297 0.703
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.297 0.703
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.298 0.702
K51 Ulcerative colitis
0.700 0.299 0.001
J32.1 Chronic frontal sinusitis
0.000 0.301 0.699
H60.4 Cholesteatoma of external ear
0.000 0.301 0.699
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.302 0.698
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.302 0.698
G37.5 Concentric sclerosis [Balo]
0.697 0.303 0.000
G37.4 Subacute necrotising myelitis
0.697 0.303 0.000
G37.2 Central pontine myelinolysis
0.697 0.303 0.000
G37.1 Central demyelination of corpus callosum
0.697 0.303 0.000
G37.0 Diffuse sclerosis
0.697 0.303 0.000
H60.1 Cellulitis of external ear
0.000 0.303 0.697
M25.43 Effusion of joint (Forearm)
0.000 0.303 0.697
C83.3 Large cell (diffuse)
0.000 0.304 0.696
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.306 0.694
M06.38 Rheumatoid nodule (Other)
0.000 0.306 0.694
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.306 0.694
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.306 0.694
M06.33 Rheumatoid nodule (Forearm)
0.000 0.306 0.694
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.306 0.694
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.306 0.694
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.306 0.694
L40.1 Generalised pustular psoriasis
0.000 0.308 0.692
M06.8 Other specified rheumatoid arthritis
0.000 0.308 0.692
L50-L54 Urticaria and erythema
0.000 0.309 0.691
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.309 0.690
J37.0 Chronic laryngitis
0.000 0.310 0.690
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.311 0.689
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.311 0.689
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.311 0.689
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.311 0.689
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.311 0.689
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.311 0.689
L10-L14 Bullous disorders
0.000 0.311 0.689
L40.3 Pustulosis palmaris et plantaris
0.000 0.311 0.689
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.314 0.686
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.315 0.685
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.316 0.684
L43.8 Other lichen planus
0.000 0.317 0.683
K51.3 Ulcerative (chronic) rectosigmoiditis
0.683 0.317 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.683 0.317 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.318 0.682
E03.1 Congenital hypothyroidism without goitre
0.000 0.318 0.682
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.319 0.681
J43.1 Panlobular emphysema
0.000 0.319 0.681
J43.0 MacLeod's syndrome
0.000 0.319 0.681
L43.3 Subacute (active) lichen planus
0.000 0.320 0.680
L43.2 Lichenoid drug reaction
0.000 0.320 0.680
L43.1 Bullous lichen planus
0.000 0.320 0.680
L43.0 Hypertrophic lichen planus
0.000 0.320 0.680
M12 Other specific arthropathies
0.000 0.320 0.679
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.321 0.679
H91.1 Presbycusis
0.000 0.324 0.676
M25.0 Haemarthrosis
0.000 0.325 0.675
G36 Other acute disseminated demyelination
0.673 0.327 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.329 0.671
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.330 0.670
K50 Crohn's disease [regional enteritis]
0.001 0.333 0.666
H61.3 Acquired stenosis of external ear canal
0.000 0.334 0.666
H43.2 Crystalline deposits in vitreous body
0.000 0.335 0.665
E11.4 With neurological complications
0.000 0.336 0.664
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.337 0.663
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.338 0.662
M07.5 Arthropathy in ulcerative colitis
0.000 0.340 0.660
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.340 0.660
M07.2 Psoriatic spondylitis
0.000 0.340 0.660
M07.1 Arthritis mutilans
0.000 0.340 0.660
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.340 0.660
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.340 0.660
H40-H42 Glaucoma
0.000 0.341 0.659
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.345 0.655
K73.9 Chronic hepatitis, unspecified
0.000 0.346 0.654
M25.42 Effusion of joint (Upper arm)
0.000 0.349 0.651
E06.9 Thyroiditis, unspecified
0.000 0.349 0.651
H44 Disorders of globe
0.000 0.352 0.648
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.352 0.648
M25.45 Effusion of joint (Pelvic region and thigh)
0.000 0.353 0.647
H34 Retinal vascular occlusions
0.000 0.353 0.647
E06.5 Other chronic thyroiditis
0.000 0.354 0.646
E06.4 Drug-induced thyroiditis
0.000 0.354 0.646
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.354 0.646
E06.0 Acute thyroiditis
0.000 0.354 0.646
M65.8 Other synovitis and tenosynovitis
0.000 0.357 0.643
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.357 0.643
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.357 0.643
M35.5 Multifocal fibrosclerosis
0.000 0.357 0.643
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.357 0.643
M25.49 Effusion of joint (Site unspecified)
0.000 0.357 0.642
M25.48 Effusion of joint (Other)
0.000 0.357 0.642
K76 Other diseases of liver
0.000 0.360 0.640
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.361 0.639
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.362 0.638
K50.8 Other Crohn's disease
0.000 0.362 0.638
H61.1 Non-infective disorders of pinna
0.000 0.362 0.638
M60 Myositis
0.000 0.364 0.636
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.365 0.635
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.365 0.635
M25.2 Flail joint
0.000 0.365 0.635
M25.1 Fistula of joint
0.000 0.365 0.635
J39 Other diseases of upper respiratory tract
0.000 0.367 0.633
K76.8 Other specified diseases of liver
0.000 0.367 0.633
J86.0 Pyothorax with fistula
0.000 0.367 0.633
J86.9 Pyothorax without fistula
0.000 0.370 0.630
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.370 0.630
D86.0 Sarcoidosis of lung
0.628 0.372 0.000
J45 Asthma
0.000 0.372 0.628
M25.41 Effusion of joint (Shoulder region)
0.000 0.372 0.628
M07.6 Other enteropathic arthropathies
0.000 0.373 0.627
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.373 0.627
E45 Retarded development following protein-energy malnutrition
0.000 0.373 0.627
E43 Unspecified severe protein-energy malnutrition
0.000 0.373 0.627
E42 Marasmic kwashiorkor
0.000 0.373 0.627
E41 Nutritional marasmus
0.000 0.373 0.627
E40 Kwashiorkor
0.000 0.373 0.627
H91.2 Sudden idiopathic hearing loss
0.000 0.373 0.627
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.000 0.374 0.626
M07.38 Other psoriatic arthropathies (Other)
0.000 0.375 0.624
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.375 0.624
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.375 0.624
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.376 0.624
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.380 0.620
M14.6 Neuropathic arthropathy
0.000 0.382 0.618
H27.9 Disorder of lens, unspecified
0.000 0.384 0.615
C82.0 Small cleaved cell, follicular
0.000 0.386 0.613
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.000 0.390 0.610
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.390 0.610
H43.0 Vitreous prolapse
0.000 0.390 0.610
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.390 0.609
M66 Spontaneous rupture of synovium and tendon
0.000 0.393 0.607
J32.0 Chronic maxillary sinusitis
0.000 0.394 0.606
M31.9 Necrotising vasculopathy, unspecified
0.000 0.394 0.605
M30 Polyarteritis nodosa and related conditions
0.000 0.396 0.604
K90.3 Pancreatic steatorrhoea
0.000 0.397 0.603
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.397 0.603
K90.1 Tropical sprue
0.000 0.397 0.603
H91.0 Ototoxic hearing loss
0.000 0.397 0.602
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.399 0.601
K51.8 Other ulcerative colitis
0.600 0.400 0.000
H60.2 Malignant otitis externa
0.000 0.400 0.600
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.401 0.599
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.401 0.599
H60.0 Abscess of external ear
0.000 0.401 0.599
K50.1 Crohn's disease of large intestine
0.000 0.401 0.599
H61.0 Perichondritis of external ear
0.000 0.402 0.598
M10.9 Gout, unspecified
0.000 0.402 0.598
H25.2 Senile cataract, morgagnian type
0.000 0.403 0.597
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.403 0.597
J32.3 Chronic sphenoidal sinusitis
0.000 0.404 0.596
J38.5 Laryngeal spasm
0.000 0.404 0.596
E13.8 With unspecified complications
0.000 0.405 0.595
E13.7 With multiple complications
0.000 0.405 0.595
E13.6 With other specified complications
0.000 0.405 0.595
E13.5 With peripheral circulatory complications
0.000 0.405 0.595
E13.4 With neurological complications
0.000 0.405 0.595
E13.3 With ophthalmic complications
0.000 0.405 0.595
E13.2 With renal complications
0.000 0.405 0.595
E13.1 With ketoacidosis
0.000 0.405 0.595
E13.0 With coma
0.000 0.405 0.595
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.407 0.593
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.000 0.409 0.591
C91 Lymphoid leukaemia
0.000 0.411 0.589
L51 Erythema multiforme
0.000 0.412 0.588
H30.9 Chorioretinal inflammation, unspecified
0.000 0.412 0.588
D86 Sarcoidosis
0.586 0.413 0.001
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.414 0.585
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.414 0.585
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.414 0.585
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.414 0.585
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.414 0.585
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.414 0.585
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.414 0.585
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.414 0.585
E07.1 Dyshormogenetic goitre
0.000 0.415 0.585
E07.0 Hypersecretion of calcitonin
0.000 0.415 0.585
J37.1 Chronic laryngotracheitis
0.000 0.415 0.585
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.416 0.584
K90.9 Intestinal malabsorption, unspecified
0.000 0.416 0.584
C82.2 Large cell, follicular
0.000 0.417 0.583
L52 Erythema nodosum
0.000 0.418 0.582
H43.9 Disorder of vitreous body, unspecified
0.000 0.419 0.581
K75 Other inflammatory liver diseases
0.000 0.419 0.581
C85.1 B-cell lymphoma, unspecified
0.000 0.422 0.578
M60.0 Infective myositis
0.000 0.422 0.578
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.422 0.577
M35.8 Other specified systemic involvement of connective tissue
0.000 0.424 0.575
H61.2 Impacted cerumen
0.000 0.425 0.575
H91.3 Deaf mutism, not elsewhere classified
0.000 0.428 0.572
C82.3 Follicular lymphoma grade IIIa
0.000 0.428 0.571
M34.1 CR(E)ST syndrome
0.000 0.429 0.571
E06.1 Subacute thyroiditis
0.000 0.429 0.571
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.430 0.570
J35 Chronic diseases of tonsils and adenoids
0.000 0.430 0.570
K51.5 Mucosal proctocolitis
0.569 0.430 0.001
H44.0 Purulent endophthalmitis
0.000 0.432 0.568
M65.2 Calcific tendinitis
0.000 0.432 0.568
M65.0 Abscess of tendon sheath
0.000 0.432 0.568
M25.47 Effusion of joint (Ankle and foot)
0.000 0.432 0.567
M10.90 Gout, unspecified (Multiple sites)
0.000 0.433 0.567
M00-M03 Infectious arthropathies
0.000 0.435 0.565
M31.8 Other specified necrotising vasculopathies
0.000 0.436 0.564
M31.7 Microscopic polyangiitis
0.000 0.436 0.564
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.436 0.564
M31.2 Lethal midline granuloma
0.000 0.436 0.564
C95 Leukaemia of unspecified cell type
0.000 0.436 0.564
M35.7 Hypermobility syndrome
0.000 0.436 0.564
M35.2 Behcet's disease
0.000 0.436 0.564
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.437 0.563
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.437 0.563
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.438 0.562
K77 Liver disorders in diseases classified elsewhere
0.000 0.439 0.561
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.440 0.560
D86.9 Sarcoidosis, unspecified
0.560 0.440 0.000
M25.9 Joint disorder, unspecified
0.000 0.441 0.559
K72 Hepatic failure, not elsewhere classified
0.000 0.444 0.556
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.000 0.445 0.555
L42 Pityriasis rosea
0.000 0.445 0.555
M34.8 Other forms of systemic sclerosis
0.000 0.447 0.553
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.449 0.551
H60.8 Other otitis externa
0.000 0.449 0.551
L13 Other bullous disorders
0.000 0.451 0.549
C82.4 Follicular lymphoma grade IIIb
0.000 0.451 0.549
H95.1 Other disorders following mastoidectomy
0.000 0.451 0.549
M13 Other arthritis
0.000 0.452 0.548
J45.9 Asthma, unspecified
0.000 0.454 0.546
H34.1 Central retinal artery occlusion
0.000 0.455 0.545
E07.8 Other specified disorders of thyroid
0.000 0.455 0.545
J41.0 Simple chronic bronchitis
0.000 0.455 0.545
Chapter II Neoplasms
0.000 0.455 0.545
K74.4 Secondary biliary cirrhosis
0.000 0.456 0.544
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.456 0.544
K74.1 Hepatic sclerosis
0.000 0.456 0.544
C91.1 Chronic lymphocytic leukaemia
0.000 0.456 0.544
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.456 0.543
M14.4 Arthropathy in amyloidosis
0.000 0.456 0.543
M14.3 Lipoid dermatoarthritis
0.000 0.456 0.543
M14.2 Diabetic arthropathy
0.000 0.456 0.543
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.456 0.543
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.456 0.543
K50.0 Crohn's disease of small intestine
0.000 0.459 0.541
L40.8 Other psoriasis
0.000 0.459 0.541
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.460 0.540
H27.1 Dislocation of lens
0.000 0.460 0.540
M65.1 Other infective (teno)synovitis
0.000 0.460 0.540
M25.3 Other instability of joint
0.000 0.461 0.539
H92 Otalgia and effusion of ear
0.000 0.461 0.539
H34.2 Other retinal artery occlusions
0.000 0.462 0.538
H60.9 Otitis externa, unspecified
0.000 0.462 0.537
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.000 0.464 0.536
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.465 0.535
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.000 0.466 0.534
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.466 0.534
E05.9 Thyrotoxicosis, unspecified
0.000 0.467 0.533
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.468 0.532
H91.8 Other specified hearing loss
0.000 0.468 0.531
K75.4 Autoimmune hepatitis
0.000 0.469 0.531
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.469 0.531
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.469 0.531
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.469 0.531
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.469 0.531
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.469 0.531
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.469 0.531
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.469 0.531
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.469 0.531
C82.6 Cutaneous follicle centre lymphoma
0.000 0.469 0.531
C82.5 Diffuse follicle centre lymphoma
0.000 0.469 0.531
K51.2 Ulcerative (chronic) proctitis
0.529 0.470 0.000
M10.4 Other secondary gout
0.000 0.471 0.529
M10.3 Gout due to impairment of renal function
0.000 0.471 0.529
M10.2 Drug-induced gout
0.000 0.471 0.529
M10.1 Lead-induced gout
0.000 0.471 0.529
K51.4 Pseudopolyposis of colon
0.528 0.471 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.472 0.528
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.474 0.526
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.474 0.526
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.000 0.474 0.526
M25.06 Haemarthrosis (Lower leg)
0.000 0.475 0.525
J95-J99 Other diseases of the respiratory system
0.000 0.476 0.524
M25.44 Effusion of joint (Hand)
0.000 0.477 0.523
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.478 0.522
M33 Dermatopolymyositis
0.000 0.478 0.521
M11 Other crystal arthropathies
0.000 0.479 0.520
J85 Abscess of lung and mediastinum
0.000 0.480 0.519
H30.8 Other chorioretinal inflammations
0.000 0.481 0.519
H30.2 Posterior cyclitis
0.000 0.481 0.519
H30.1 Disseminated chorioretinal inflammation
0.000 0.481 0.519
H30.0 Focal chorioretinal inflammation
0.000 0.481 0.519

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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