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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130050
log Bayes Factor = 110.889
Chromosome 6   position 31,618,761  (GRCh37) Explore rs3130050 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
# Top node
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
H36.0 Diabetic retinopathy
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.003 0.997
H30-H36 Disorders of choroid and retina
0.000 0.003 0.997
E14.9 Without complications
0.000 0.003 0.997
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.003 0.997
I20.9 Angina pectoris, unspecified
0.000 0.004 0.996
E83.1 Disorders of iron metabolism
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.004 0.996
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.004 0.996
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
G37.9 Demyelinating disease of central nervous system, unspecified
0.995 0.005 0.000
I22 Subsequent myocardial infarction
0.000 0.005 0.995
E10.4 With neurological complications
0.000 0.006 0.994
L43 Lichen planus
0.000 0.006 0.994
E70-E90 Metabolic disorders
0.000 0.010 0.990
L43.9 Lichen planus, unspecified
0.000 0.012 0.988
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.012 0.988
H43-H45 Disorders of vitreous body and globe
0.000 0.015 0.985
M45-M49 Spondylopathies
0.000 0.015 0.985
M45 Ankylosing spondylitis
0.000 0.016 0.984
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.017 0.983
H43 Disorders of vitreous body
0.000 0.019 0.981
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.019 0.981
I25.5 Ischaemic cardiomyopathy
0.000 0.022 0.978
J45.9 Asthma, unspecified
0.000 0.025 0.975
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.026 0.974
E14.3 With ophthalmic complications
0.000 0.028 0.972
I20.0 Unstable angina
0.000 0.032 0.968
H43.8 Other disorders of vitreous body
0.000 0.034 0.966
Chapter VI Diseases of the nervous system
0.962 0.038 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.042 0.958
E16 Other disorders of pancreatic internal secretion
0.000 0.045 0.955
G20-G26 Extrapyramidal and movement disorders
0.955 0.045 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.048 0.952
G20 Parkinson's disease
0.950 0.050 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.059 0.941
M70-M79 Other soft tissue disorders
0.000 0.066 0.934
E07 Other disorders of thyroid
0.000 0.067 0.933
H43.3 Other vitreous opacities
0.000 0.071 0.929
I12 Hypertensive renal disease
0.000 0.073 0.927
H35 Other retinal disorders
0.000 0.076 0.924
H34 Retinal vascular occlusions
0.000 0.076 0.924
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.076 0.924
I24 Other acute ischaemic heart diseases
0.000 0.084 0.916
H35.8 Other specified retinal disorders
0.000 0.095 0.905
M07 Psoriatic and enteropathic arthropathies
0.000 0.095 0.905
G37.8 Other specified demyelinating diseases of central nervous system
0.903 0.097 0.000
E10.5 With peripheral circulatory complications
0.000 0.103 0.897
I15 Secondary hypertension
0.000 0.107 0.893
E13 Other specified diabetes mellitus
0.000 0.109 0.891
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.111 0.889
M05 Seropositive rheumatoid arthritis
0.000 0.115 0.885
E07.9 Disorder of thyroid, unspecified
0.000 0.116 0.884
I12.9 Hypertensive renal disease without renal failure
0.000 0.116 0.884
E11.3 With ophthalmic complications
0.000 0.116 0.884
E78.8 Other disorders of lipoprotein metabolism
0.000 0.117 0.883
E78.2 Mixed hyperlipidaemia
0.000 0.120 0.880
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.122 0.878
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.123 0.877
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.130 0.870
M75 Shoulder lesions
0.000 0.135 0.865
I20.1 Angina pectoris with documented spasm
0.000 0.143 0.857
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.144 0.856
E10.2 With renal complications
0.000 0.147 0.853
E10.8 With unspecified complications
0.000 0.148 0.852
H34.8 Other retinal vascular occlusions
0.000 0.158 0.842
M06.3 Rheumatoid nodule
0.000 0.160 0.840
M07.3 Other psoriatic arthropathies
0.000 0.163 0.837
M77 Other enthesopathies
0.000 0.164 0.836
I25.3 Aneurysm of heart
0.000 0.164 0.836
K90 Intestinal malabsorption
0.000 0.167 0.833
E11.1 With ketoacidosis
0.000 0.167 0.832
G30-G32 Other degenerative diseases of the nervous system
0.832 0.168 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.170 0.830
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.170 0.829
E11.2 With renal complications
0.000 0.172 0.828
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.173 0.827
M75.0 Adhesive capsulitis of shoulder
0.000 0.174 0.826
M65-M68 Disorders of synovium and tendon
0.000 0.181 0.819
I15.1 Hypertension secondary to other renal disorders
0.000 0.184 0.816
E13.9 Without complications
0.000 0.188 0.812
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.188 0.812
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.193 0.807
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.196 0.804
L43.8 Other lichen planus
0.000 0.198 0.802
I25.2 Old myocardial infarction
0.000 0.200 0.800
G25 Other extrapyramidal and movement disorders
0.792 0.208 0.000
L40.8 Other psoriasis
0.000 0.210 0.790
K90-K93 Other diseases of the digestive system
0.000 0.211 0.789
Chapter XI Diseases of the digestive system
0.000 0.214 0.786
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.216 0.784
M77.1 Lateral epicondylitis
0.000 0.217 0.783
E11.0 With coma
0.000 0.217 0.783
E05.9 Thyrotoxicosis, unspecified
0.000 0.219 0.781
K70-K77 Diseases of liver
0.000 0.220 0.780
K74 Fibrosis and cirrhosis of liver
0.000 0.222 0.778
E06 Thyroiditis
0.000 0.222 0.778
I11 Hypertensive heart disease
0.000 0.227 0.773
E78.4 Other hyperlipidaemia
0.000 0.229 0.771
E83 Disorders of mineral metabolism
0.699 0.233 0.068
K74.3 Primary biliary cirrhosis
0.000 0.233 0.767
G00-G09 Inflammatory diseases of the central nervous system
0.766 0.234 0.000
H43.9 Disorder of vitreous body, unspecified
0.000 0.240 0.760
E03.8 Other specified hypothyroidism
0.000 0.241 0.759
E40-E46 Malnutrition
0.000 0.242 0.758
M75.2 Bicipital tendinitis
0.000 0.243 0.757
E74 Other disorders of carbohydrate metabolism
0.000 0.244 0.756
M65 Synovitis and tenosynovitis
0.000 0.245 0.755
H35.4 Peripheral retinal degeneration
0.000 0.245 0.755
M70.4 Prepatellar bursitis
0.000 0.247 0.753
M11 Other crystal arthropathies
0.000 0.249 0.751
I23 Certain current complications following acute myocardial infarction
0.000 0.251 0.749
M06.0 Seronegative rheumatoid arthritis
0.000 0.251 0.749
E11.5 With peripheral circulatory complications
0.000 0.251 0.749
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.252 0.748
H43.2 Crystalline deposits in vitreous body
0.000 0.254 0.746
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.255 0.745
G40-G47 Episodic and paroxysmal disorders
0.743 0.257 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.261 0.739
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.263 0.736
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.264 0.736
E14.4 With neurological complications
0.000 0.269 0.731
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.270 0.730
H34.2 Other retinal artery occlusions
0.000 0.271 0.729
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.271 0.729
H40-H42 Glaucoma
0.000 0.271 0.729
L40.0 Psoriasis vulgaris
0.000 0.274 0.726
H35.6 Retinal haemorrhage
0.000 0.274 0.726
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.275 0.725
E78.1 Pure hyperglyceridaemia
0.000 0.276 0.724
M75.4 Impingement syndrome of shoulder
0.000 0.277 0.723
M75.3 Calcific tendinitis of shoulder
0.000 0.279 0.721
M14 Arthropathies in other diseases classified elsewhere
0.000 0.280 0.720
G80-G83 Cerebral palsy and other paralytic syndromes
0.719 0.281 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.281 0.719
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.718 0.282 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.716
M08 Juvenile arthritis
0.000 0.283 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
H35.2 Other proliferative retinopathy
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.285 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.715
H30 Chorioretinal inflammation
0.000 0.285 0.715
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.285 0.715
E78.6 Lipoprotein deficiency
0.000 0.286 0.714
E78.3 Hyperchylomicronaemia
0.000 0.286 0.714
M49 Spondylopathies in diseases classified elsewhere
0.000 0.287 0.713
L43.3 Subacute (active) lichen planus
0.000 0.288 0.712
L43.2 Lichenoid drug reaction
0.000 0.288 0.712
L43.1 Bullous lichen planus
0.000 0.288 0.712
L43.0 Hypertrophic lichen planus
0.000 0.288 0.712
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.289 0.711
E77 Disorders of glycoprotein metabolism
0.000 0.290 0.710
E76 Disorders of glycosaminoglycan metabolism
0.000 0.290 0.710
E72 Other disorders of amino-acid metabolism
0.000 0.290 0.710
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.290 0.710
E70 Disorders of aromatic amino-acid metabolism
0.000 0.290 0.710
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.290 0.710
M06.34 Rheumatoid nodule (Hand)
0.000 0.291 0.709
M46 Other inflammatory spondylopathies
0.000 0.293 0.707
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.294 0.706
H34.1 Central retinal artery occlusion
0.000 0.294 0.706
G30 Alzheimer's disease
0.706 0.294 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.294 0.706
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.294 0.706
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.294 0.706
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.294 0.706
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.294 0.706
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.294 0.706
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.294 0.706
H43.0 Vitreous prolapse
0.000 0.296 0.703
M06.4 Inflammatory polyarthropathy
0.000 0.297 0.703
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.299 0.701
E15 Nondiabetic hypoglycaemic coma
0.000 0.302 0.698
K74.5 Biliary cirrhosis, unspecified
0.000 0.303 0.697
E79 Disorders of purine and pyrimidine metabolism
0.000 0.303 0.697
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.305 0.695
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.305 0.695
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.307 0.693
L42 Pityriasis rosea
0.000 0.309 0.691
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.315 0.685
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.315 0.685
E16.4 Abnormal secretion of gastrin
0.000 0.315 0.685
E16.3 Increased secretion of glucagon
0.000 0.315 0.685
E16.1 Other hypoglycaemia
0.000 0.315 0.685
G23 Other degenerative diseases of basal ganglia
0.685 0.315 0.000
G21 Secondary Parkinsonism
0.685 0.315 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.685 0.315 0.000
G22 Parkinsonism in diseases classified elsewhere
0.685 0.315 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.315 0.684
E11.8 With unspecified complications
0.000 0.316 0.684
K74.6 Other and unspecified cirrhosis of liver
0.000 0.319 0.681
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.320 0.680
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.326 0.674
E07.8 Other specified disorders of thyroid
0.000 0.326 0.673
E14.6 With other specified complications
0.000 0.327 0.672
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.329 0.671
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.330 0.670
E07.1 Dyshormogenetic goitre
0.000 0.331 0.669
E07.0 Hypersecretion of calcitonin
0.000 0.331 0.669
H35.5 Hereditary retinal dystrophy
0.000 0.336 0.664
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.336 0.664
M12 Other specific arthropathies
0.000 0.336 0.663
E11.6 With other specified complications
0.000 0.337 0.663
H35.1 Retinopathy of prematurity
0.000 0.337 0.663
H34.0 Transient retinal artery occlusion
0.000 0.338 0.662
G46 Vascular syndromes of brain in cerebrovascular diseases
0.656 0.344 0.000
M77.5 Other enthesopathy of foot
0.000 0.345 0.655
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.346 0.654
M71 Other bursopathies
0.000 0.346 0.654
K73 Chronic hepatitis, not elsewhere classified
0.000 0.346 0.654
E06.3 Autoimmune thyroiditis
0.000 0.350 0.650
I25.4 Coronary artery aneurysm
0.000 0.351 0.649
H34.9 Retinal vascular occlusion, unspecified
0.000 0.351 0.649
M07.6 Other enteropathic arthropathies
0.000 0.351 0.648
M07.5 Arthropathy in ulcerative colitis
0.000 0.351 0.648
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.351 0.648
M07.2 Psoriatic spondylitis
0.000 0.351 0.648
M07.1 Arthritis mutilans
0.000 0.351 0.648
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.351 0.648
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.648 0.352 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.645 0.355 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.644 0.356 0.000
E84 Cystic fibrosis
0.001 0.356 0.643
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.357 0.643
H31 Other disorders of choroid
0.000 0.359 0.641
I22.8 Subsequent myocardial infarction of other sites
0.000 0.359 0.641
K72.9 Hepatic failure, unspecified
0.000 0.359 0.640
I15.9 Seconday hypertension, unspecified
0.000 0.360 0.640
I15.8 Other secondary hypertension
0.000 0.360 0.640
I15.2 Hypertension secondary to endocrine disorders
0.000 0.360 0.640
I15.0 Renovascular hypertension
0.000 0.360 0.640
L10-L14 Bullous disorders
0.000 0.361 0.639
E13.8 With unspecified complications
0.000 0.361 0.639
E13.7 With multiple complications
0.000 0.361 0.639
E13.6 With other specified complications
0.000 0.361 0.639
E13.5 With peripheral circulatory complications
0.000 0.361 0.639
E13.4 With neurological complications
0.000 0.361 0.639
E13.3 With ophthalmic complications
0.000 0.361 0.639
E13.2 With renal complications
0.000 0.361 0.639
E13.1 With ketoacidosis
0.000 0.361 0.639
E13.0 With coma
0.000 0.361 0.639
E83.3 Disorders of phosphorus metabolism
0.616 0.362 0.022
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.362 0.638
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.637 0.362 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.365 0.635
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.365 0.635
M05.2 Rheumatoid vasculitis
0.000 0.365 0.635
M05.1 Rheumatoid lung disease
0.000 0.365 0.635
M05.0 Felty's syndrome
0.000 0.365 0.635
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.365 0.635
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.367 0.633
H35.7 Separation of retinal layers
0.000 0.369 0.631
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.370 0.630
E05.5 Thyroid crisis or storm
0.000 0.370 0.630
E05.4 Thyrotoxicosis factitia
0.000 0.370 0.630
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.370 0.630
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.370 0.630
G09 Sequelae of inflammatory diseases of central nervous system
0.628 0.372 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.374 0.626
L40.3 Pustulosis palmaris et plantaris
0.000 0.374 0.625
I30-I52 Other forms of heart disease
0.000 0.376 0.624
G00 Bacterial meningitis, not elsewhere classified
0.622 0.378 0.000
I47 Paroxysmal tachycardia
0.000 0.378 0.622
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.379 0.621
M75.8 Other shoulder lesions
0.000 0.379 0.620
M77.0 Medial epicondylitis
0.000 0.382 0.618
G41 Status epilepticus
0.618 0.382 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.383 0.616
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.384 0.616
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.609 0.391 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.001 0.393 0.606
I12.0 Hypertensive renal disease with renal failure
0.000 0.394 0.606
K72.0 Acute and subacute hepatic failure
0.000 0.397 0.603
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.397 0.602
M06.38 Rheumatoid nodule (Other)
0.000 0.397 0.602
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.397 0.602
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.397 0.602
M06.33 Rheumatoid nodule (Forearm)
0.000 0.397 0.602
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.397 0.602
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.397 0.602
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.397 0.602
M00-M03 Infectious arthropathies
0.000 0.399 0.600
G25.2 Other specified forms of tremor
0.600 0.400 0.000
M07.38 Other psoriatic arthropathies (Other)
0.000 0.400 0.600
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.400 0.600
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.400 0.600
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.400 0.600
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.400 0.600
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.400 0.600
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.400 0.600
M77.3 Calcaneal spur
0.000 0.400 0.600
M77.2 Periarthritis of wrist
0.000 0.400 0.600
H43.1 Vitreous haemorrhage
0.000 0.401 0.599
K90.3 Pancreatic steatorrhoea
0.000 0.403 0.597
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.403 0.597
K90.1 Tropical sprue
0.000 0.403 0.597
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.405 0.595
G40 Epilepsy
0.594 0.406 0.000
M70.5 Other bursitis of knee
0.000 0.406 0.594
G30.9 Alzheimer's disease, unspecified
0.592 0.408 0.000
M70.7 Other bursitis of hip
0.000 0.410 0.590
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.412 0.588
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.413 0.587
M91-M94 Chondropathies
0.000 0.413 0.587
I35.0 Aortic (valve) stenosis
0.000 0.413 0.587
G90-G99 Other disorders of the nervous system
0.585 0.415 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.415 0.585
I35 Nonrheumatic aortic valve disorders
0.000 0.415 0.585
H35.9 Retinal disorder, unspecified
0.000 0.416 0.584
I47.1 Supraventricular tachycardia
0.000 0.416 0.584
G31.9 Degenerative disease of nervous system, unspecified
0.583 0.417 0.000
G44 Other headache syndromes
0.583 0.417 0.000
I51 Complications and ill-defined descriptions of heart disease
0.000 0.417 0.583
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.418 0.582
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.418 0.582
M70.1 Bursitis of hand
0.000 0.418 0.582
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.418 0.582
G06 Intracranial and intraspinal abscess and granuloma
0.580 0.420 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.423 0.576
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.423 0.576
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.423 0.576
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.423 0.576
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.423 0.576
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.423 0.576
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.423 0.576
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.423 0.576
I05-I09 Chronic rheumatic heart diseases
0.000 0.425 0.575
I51.8 Other ill-defined heart diseases
0.000 0.425 0.575
I24.1 Dressler's syndrome
0.000 0.426 0.573
M65.8 Other synovitis and tenosynovitis
0.000 0.426 0.573
I21 Acute myocardial infarction
0.000 0.427 0.573
M11.2 Other chondrocalcinosis
0.000 0.427 0.573
G83 Other paralytic syndromes
0.573 0.427 0.000
M75.9 Shoulder lesion, unspecified
0.000 0.428 0.572
I47.2 Ventricular tachycardia
0.000 0.428 0.572
G30.8 Other Alzheimer's disease
0.571 0.429 0.000
G25.3 Myoclonus
0.570 0.429 0.000
I23.8 Other current complications following acute myocardial infarction
0.000 0.430 0.570
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.569 0.431 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.568 0.432 0.000
G25.5 Other chorea
0.568 0.432 0.000
G25.4 Drug-induced chorea
0.568 0.432 0.000
G25.1 Drug-induced tremor
0.568 0.432 0.000
Chapter VIII Diseases of the ear and mastoid process
0.000 0.432 0.568
G46.7 Other lacunar syndromes
0.566 0.434 0.000
G47 Sleep disorders
0.566 0.434 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.434 0.565
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.435 0.565
E11.4 With neurological complications
0.000 0.435 0.565
K90.8 Other intestinal malabsorption
0.000 0.436 0.564
E89.3 Postprocedural hypopituitarism
0.000 0.437 0.563
M77.19 Lateral epicondylitis (Site unspecified)
0.000 0.438 0.562
M77.18 Lateral epicondylitis-Other
0.000 0.438 0.562
M77.17 Lateral epicondylitis-Ankle/Foot
0.000 0.438 0.562
M77.16 Lateral epicondylitis (Lower leg)
0.000 0.438 0.562
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.000 0.438 0.562
M77.14 Lateral epicondylitis-Hand
0.000 0.438 0.562
M77.13 Lateral epicondylitis-Forearm
0.000 0.438 0.562
M77.11 Lateral epicondylitis-Shldr region
0.000 0.438 0.562
M77.10 Lateral epicondylitis (Multiple sites)
0.000 0.438 0.562
G03 Meningitis due to other and unspecified causes
0.561 0.439 0.000
E88 Other metabolic disorders
0.001 0.439 0.560
K77 Liver disorders in diseases classified elsewhere
0.000 0.440 0.560
K71 Toxic liver disease
0.000 0.440 0.560
E73 Lactose intolerance
0.001 0.441 0.558
M46.4 Discitis, unspecified
0.000 0.441 0.558
K74.4 Secondary biliary cirrhosis
0.000 0.442 0.558
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.442 0.558
K74.1 Hepatic sclerosis
0.000 0.442 0.558
E06.5 Other chronic thyroiditis
0.000 0.442 0.557
E06.4 Drug-induced thyroiditis
0.000 0.442 0.557
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.442 0.557
E06.1 Subacute thyroiditis
0.000 0.442 0.557
E06.0 Acute thyroiditis
0.000 0.442 0.557
M77.4 Metatarsalgia
0.000 0.442 0.557
M70.3 Other bursitis of elbow
0.000 0.443 0.556
E05.8 Other thyrotoxicosis
0.000 0.444 0.556
E83.9 Disorder of mineral metabolism, unspecified
0.501 0.450 0.049
E83.8 Other disorders of mineral metabolism
0.501 0.450 0.049
E83.2 Disorders of zinc metabolism
0.501 0.450 0.049
E83.0 Disorders of copper metabolism
0.501 0.450 0.049
M65.1 Other infective (teno)synovitis
0.000 0.451 0.549
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.549 0.451 0.000
Q50-Q56 Congenital malformations of genital organs
0.000 0.452 0.548
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.453 0.547
E85 Amyloidosis
0.001 0.453 0.546
M76 Enthesopathies of lower limb, excluding foot
0.000 0.454 0.546
K75 Other inflammatory liver diseases
0.000 0.454 0.546
H60-H62 Diseases of external ear
0.000 0.454 0.546
G81 Hemiplegia
0.545 0.455 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.456 0.544
E45 Retarded development following protein-energy malnutrition
0.000 0.456 0.544
E43 Unspecified severe protein-energy malnutrition
0.000 0.456 0.544
E42 Marasmic kwashiorkor
0.000 0.456 0.544
E41 Nutritional marasmus
0.000 0.456 0.544
E40 Kwashiorkor
0.000 0.456 0.544
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.456 0.544
M70.2 Olecranon bursitis
0.000 0.456 0.543
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.458 0.542
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.458 0.542
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.458 0.542
E74.2 Disorders of galactose metabolism
0.000 0.458 0.542
E74.1 Disorders of fructose metabolism
0.000 0.458 0.542
E74.0 Glycogen storage disease
0.000 0.458 0.542
M65.2 Calcific tendinitis
0.000 0.458 0.542
M65.0 Abscess of tendon sheath
0.000 0.458 0.542
M70.49 Prepatellar bursitis-Site unspec
0.000 0.460 0.540
M70.48 Prepatellar bursitis-Other
0.000 0.460 0.540
M70.47 Prepatellar bursitis-Ankle/Foot
0.000 0.460 0.540
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.000 0.460 0.540
M70.44 Prepatellar bursitis-Hand
0.000 0.460 0.540
M70.43 Prepatellar bursitis-Forearm
0.000 0.460 0.540
M70.42 Prepatellar bursitis-Upper arm
0.000 0.460 0.540
M70.41 Prepatellar bursitis-Shldr region
0.000 0.460 0.540
M70.40 Prepatellar bursitis-Mult sites
0.000 0.460 0.540
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.460 0.540
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.461 0.539
H35.0 Background retinopathy and retinal vascular changes
0.000 0.461 0.539
E78.5 Hyperlipidaemia, unspecified
0.000 0.461 0.539
M11.9 Crystal arthropathy, unspecified
0.000 0.461 0.538
M11.8 Other specified crystal arthropathies
0.000 0.461 0.538
M11.1 Familial chondrocalcinosis
0.000 0.461 0.538
M11.0 Hydroxyapatite deposition disease
0.000 0.461 0.538
M71.2 Synovial cyst of popliteal space [Baker]
0.000 0.462 0.538
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.463 0.537
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.463 0.537
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.463 0.537
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.463 0.537
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.463 0.537

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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