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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130361
log Bayes Factor = 40.0053
Chromosome 6   position 30,339,564  (GRCh37) Explore rs3130361 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.999 0.001 0.000
G20-G26 Extrapyramidal and movement disorders
0.999 0.001 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
G25 Other extrapyramidal and movement disorders
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
E10.3 With ophthalmic complications
0.000 0.004 0.996
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
G25.8 Other specified extrapyramidal and movement disorders
0.995 0.005 0.000
G24 Dystonia
0.992 0.008 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.010 0.990
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.019 0.981
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.057 0.943
E10.2 With renal complications
0.000 0.058 0.942
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.068 0.932
G20 Parkinson's disease
0.931 0.069 0.000
E10.1 With ketoacidosis
0.000 0.072 0.928
G90-G99 Other disorders of the nervous system
0.927 0.073 0.000
G24.9 Dystonia, unspecified
0.926 0.074 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.085 0.915
G30-G32 Other degenerative diseases of the nervous system
0.906 0.094 0.000
G24.8 Other dystonia
0.903 0.097 0.000
E10.4 With neurological complications
0.000 0.108 0.892
G96 Other disorders of central nervous system
0.872 0.128 0.000
K90.0 Coeliac disease
0.000 0.128 0.872
G93 Other disorders of brain
0.871 0.129 0.000
G93.4 Encephalopathy, unspecified
0.856 0.144 0.000
G24.3 Spasmodic torticollis
0.844 0.156 0.000
G25.5 Other chorea
0.843 0.157 0.000
E10.0 With coma
0.000 0.157 0.843
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.183 0.817
G96.0 Cerebrospinal fluid leak
0.813 0.187 0.000
G25.1 Drug-induced tremor
0.809 0.191 0.000
G24.0 Drug-induced dystonia
0.805 0.195 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.791 0.209 0.000
G40-G47 Episodic and paroxysmal disorders
0.787 0.213 0.000
G37 Other demyelinating diseases of central nervous system
0.786 0.214 0.000
G24.5 Blepharospasm
0.784 0.216 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.783 0.217 0.000
G30 Alzheimer's disease
0.772 0.228 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.249 0.751
G93.3 Postviral fatigue syndrome
0.749 0.251 0.000
G93.8 Other specified disorders of brain
0.749 0.251 0.000
G40 Epilepsy
0.745 0.255 0.000
G31.2 Degeneration of nervous system due to alcohol
0.728 0.272 0.000
G21 Secondary Parkinsonism
0.728 0.272 0.000
G23 Other degenerative diseases of basal ganglia
0.727 0.273 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.725 0.275 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.275 0.725
G95 Other diseases of spinal cord
0.717 0.283 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.716 0.283 0.000
G22 Parkinsonism in diseases classified elsewhere
0.716 0.283 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.716 0.284 0.000
G36 Other acute disseminated demyelination
0.715 0.284 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.715 0.285 0.000
G25.4 Drug-induced chorea
0.715 0.285 0.000
G25.2 Other specified forms of tremor
0.715 0.285 0.000
G24.4 Idiopathic orofacial dystonia
0.711 0.289 0.000
G24.2 Idiopathic nonfamilial dystonia
0.711 0.289 0.000
G24.1 Idiopathic familial dystonia
0.711 0.289 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.707 0.293 0.000
G25.3 Myoclonus
0.705 0.295 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.704 0.296 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.703 0.297 0.000
G40.9 Epilepsy, unspecified
0.699 0.301 0.000
E10.8 With unspecified complications
0.000 0.302 0.698
G96.1 Disorders of meninges, not elsewhere classified
0.697 0.303 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.683 0.317 0.000
G92 Toxic encephalopathy
0.665 0.335 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.663 0.337 0.000
G46.7 Other lacunar syndromes
0.653 0.347 0.000
E10.7 With multiple complications
0.000 0.350 0.650
G30.0 Alzheimer's disease with early onset
0.650 0.350 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.650 0.350 0.000
G41 Status epilepticus
0.647 0.353 0.000
G96.8 Other specified disorders of central nervous system
0.642 0.358 0.000
E10.5 With peripheral circulatory complications
0.000 0.365 0.635
G96.9 Disorder of central nervous system, unspecified
0.625 0.374 0.000
G93.7 Reye's syndrome
0.624 0.375 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.621 0.379 0.000
G30.8 Other Alzheimer's disease
0.619 0.381 0.000
G97.8 Other postprocedural disorders of nervous system
0.612 0.388 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.611 0.389 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.606 0.394 0.000
G95.0 Syringomyelia and syringobulbia
0.601 0.399 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.601 0.399 0.000
K90 Intestinal malabsorption
0.000 0.400 0.600
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.598 0.402 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.596 0.404 0.000
G31.0 Circumscribed brain atrophy
0.596 0.404 0.000
E10.6 With other specified complications
0.000 0.414 0.586
G93.5 Compression of brain
0.586 0.414 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.567 0.433 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.567 0.433 0.000
G37.5 Concentric sclerosis [Balo]
0.563 0.437 0.000
G37.4 Subacute necrotising myelitis
0.563 0.437 0.000
G37.2 Central pontine myelinolysis
0.563 0.437 0.000
G37.1 Central demyelination of corpus callosum
0.563 0.437 0.000
G37.0 Diffuse sclerosis
0.563 0.437 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.438 0.562
G25.0 Essential tremor
0.562 0.438 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.561 0.439 0.000
G43 Migraine
0.560 0.440 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.559 0.441 0.000
G30.1 Alzheimer's disease with late onset
0.554 0.446 0.000
G95.2 Cord compression, unspecified
0.553 0.447 0.000
G95.8 Other specified diseases of spinal cord
0.550 0.450 0.000
G93.6 Cerebral oedema
0.542 0.458 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.541 0.459 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.534 0.466 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.533 0.467 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.532 0.467 0.000
G41.9 Status epilepticus, unspecified
0.527 0.473 0.000
G30.9 Alzheimer's disease, unspecified
0.527 0.473 0.000
G21.9 Secondary Parkinsonism, unspecified
0.522 0.478 0.000
G21.8 Other secondary Parkinsonism
0.522 0.478 0.000
G21.4 Vascular parkinsonism
0.522 0.478 0.000
G21.3 Postencephalitic Parkinsonism
0.522 0.478 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.522 0.478 0.000
G21.0 Malignant neuroleptic syndrome
0.522 0.478 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.521 0.478 0.000
G23.3 Multiple system atrophy, cerebellar type
0.521 0.478 0.000
G23.2 Striatonigral degeneration
0.521 0.478 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.521 0.478 0.000
G23.0 Hallervorden-Spatz disease
0.521 0.478 0.000
G43.8 Other migraine
0.519 0.481 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.515 0.485 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.514 0.486 0.000
G36.9 Acute disseminated demyelination, unspecified
0.513 0.487 0.000
G36.8 Other specified acute disseminated demyelination
0.513 0.487 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.513 0.487 0.000
G36.0 Neuromyelitis optica [Devic]
0.513 0.487 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.492 0.508
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.507 0.493 0.000
G46.6 Pure sensory lacunar syndrome
0.507 0.493 0.000
G46.5 Pure motor lacunar syndrome
0.507 0.493 0.000
G46.3 Brain stem stroke syndrome
0.507 0.493 0.000
G46.2 Posterior cerebral artery syndrome
0.507 0.493 0.000
G46.1 Anterior cerebral artery syndrome
0.507 0.493 0.000
G46.0 Middle cerebral artery syndrome
0.507 0.493 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.506 0.494 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.504 0.495 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.504 0.495 0.000
G41.0 Grand mal status epilepticus
0.494 0.506 0.000
G46.4 Cerebellar stroke syndrome
0.493 0.506 0.000
G40.5 Special epileptic syndromes
0.490 0.509 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.478 0.522 0.000
K90.8 Other intestinal malabsorption
0.000 0.527 0.473
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.466 0.534 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.466 0.534 0.000
G41.8 Other status epilepticus
0.464 0.536 0.000
G41.2 Complex partial status epilepticus
0.464 0.536 0.000
G41.1 Petit mal status epilepticus
0.464 0.536 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.462 0.538 0.000
G03 Meningitis due to other and unspecified causes
0.461 0.539 0.000
M06 Other rheumatoid arthritis
0.000 0.540 0.460
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.544 0.456
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.452 0.548 0.000
G95.1 Vascular myelopathies
0.450 0.550 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.443 0.557 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.441 0.559 0.000
G11 Hereditary ataxia
0.439 0.561 0.000
G93.2 Benign intracranial hypertension
0.438 0.562 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.437 0.563 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.431 0.569 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.570 0.430
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.570 0.430
K90.1 Tropical sprue
0.000 0.570 0.430
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.427 0.572 0.000
G14 Postpolio syndrome
0.427 0.572 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.424 0.576 0.000
G40.8 Other epilepsy
0.422 0.578 0.000
G10 Huntington's disease
0.421 0.579 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.417 0.583 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.417 0.583 0.000
G95.9 Disease of spinal cord, unspecified
0.414 0.586 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.412 0.588 0.000
G00 Bacterial meningitis, not elsewhere classified
0.405 0.595 0.000
G43.3 Complicated migraine
0.401 0.598 0.000
G43.2 Status migrainosus
0.401 0.598 0.000
G44 Other headache syndromes
0.399 0.601 0.000
G70-G73 Diseases of myoneural junction and muscle
0.397 0.602 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.378 0.622 0.000
G43.0 Migraine without aura [common migraine]
0.376 0.624 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.373 0.626 0.000
G43.1 Migraine with aura [classical migraine]
0.372 0.628 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.368 0.631 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.368 0.631 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.368 0.631 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.363 0.637 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.363 0.637 0.000
G03.9 Meningitis, unspecified
0.361 0.639 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.356 0.644 0.000
G11.4 Hereditary spastic paraplegia
0.342 0.658 0.000
G82 Paraplegia and tetraplegia
0.337 0.663 0.000
G03.8 Meningitis due to other specified causes
0.331 0.669 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.331 0.669 0.000
G03.1 Chronic meningitis
0.331 0.669 0.000
G03.0 Nonpyogenic meningitis
0.331 0.669 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.670 0.330
M06.2 Rheumatoid bursitis
0.000 0.670 0.330
M06.1 Adult-onset Still's disease
0.000 0.670 0.330
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.328 0.672 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.673 0.327
M06.4 Inflammatory polyarthropathy
0.000 0.676 0.324
G06.2 Extradural and subdural abscess, unspecified
0.320 0.680 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.316 0.684 0.000
G04.1 Tropical spastic paraplegia
0.316 0.684 0.000
G04.0 Acute disseminated encephalitis
0.316 0.684 0.000
G94.1 Hydrocephalus in neoplastic disease
0.316 0.684 0.000
G11.8 Other hereditary ataxias
0.315 0.685 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.315 0.685 0.000
G11.2 Late-onset cerebellar ataxia
0.315 0.685 0.000
G11.1 Early-onset cerebellar ataxia
0.315 0.685 0.000
G11.0 Congenital nonprogressive ataxia
0.315 0.685 0.000
G00.2 Streptococcal meningitis
0.308 0.692 0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.306 0.693 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.306 0.693 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.306 0.693 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.306 0.693 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.302 0.697 0.001
G06.1 Intraspinal abscess and granuloma
0.300 0.699 0.000
G00.1 Pneumococcal meningitis
0.300 0.700 0.000
G12 Spinal muscular atrophy and related syndromes
0.299 0.701 0.001
G82.1 Spastic paraplegia
0.299 0.701 0.000
G91 Hydrocephalus
0.296 0.703 0.001
G11.9 Hereditary ataxia, unspecified
0.295 0.705 0.000
G44.3 Chronic posttraumatic headache
0.294 0.706 0.000
G00.8 Other bacterial meningitis
0.290 0.709 0.000
G00.3 Staphylococcal meningitis
0.290 0.709 0.000
G00.0 Haemophilus meningitis
0.290 0.709 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.712 0.288
G44.1 Vascular headache, not elsewhere classified
0.286 0.713 0.000
G83 Other paralytic syndromes
0.286 0.714 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.285 0.715 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.280 0.720 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.279 0.721 0.001
E10-E14 Diabetes mellitus
0.000 0.724 0.276
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.273 0.727 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.268 0.732 0.000
G02.1 Meningitis in mycoses
0.268 0.732 0.000
G44.0 Cluster headache syndrome
0.268 0.732 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.262 0.738 0.000
M06.3 Rheumatoid nodule
0.000 0.741 0.259
G06.0 Intracranial abscess and granuloma
0.255 0.745 0.000
G93.0 Cerebral cysts
0.253 0.746 0.001
G71 Primary disorders of muscles
0.250 0.750 0.000
G31.8 Other specified degenerative diseases of nervous system
0.249 0.750 0.001
G82.5 Tetraplegia, unspecified
0.248 0.752 0.000
G93.9 Disorder of brain, unspecified
0.245 0.754 0.001
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.754 0.246
G82.3 Flaccid tetraplegia
0.242 0.758 0.000
G82.0 Flaccid paraplegia
0.242 0.758 0.000
G90 Disorders of autonomic nervous system
0.238 0.759 0.003
G44.8 Other specified headache syndromes
0.240 0.760 0.000
E13 Other specified diabetes mellitus
0.000 0.762 0.238
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.763 0.237
M06.18 Adult-onset Still's disease (Other)
0.000 0.763 0.237
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.763 0.237
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.763 0.237
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.763 0.237
M06.14 Adult-onset Still's disease (Hand)
0.000 0.763 0.237
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.763 0.237
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.763 0.237
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.763 0.237
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.763 0.237
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.763 0.237
M06.28 Rheumatoid bursitis (Other)
0.000 0.763 0.237
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.763 0.237
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.763 0.237
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.763 0.237
M06.24 Rheumatoid bursitis (Hand)
0.000 0.763 0.237
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.763 0.237
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.763 0.237
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.763 0.237
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.763 0.237
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.763 0.237
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.763 0.237
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.763 0.237
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.763 0.237
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.763 0.237
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.763 0.237
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.763 0.237
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.763 0.237
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.763 0.237
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.763 0.237
G82.4 Spastic tetraplegia
0.236 0.764 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.765 0.235
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.765 0.235
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.765 0.235
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.765 0.235
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.765 0.235
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.765 0.235
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.765 0.235
G80 Infantile cerebral palsy
0.234 0.766 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.768 0.232
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.768 0.232
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.768 0.232
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.768 0.232
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.768 0.232
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.768 0.232
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.768 0.232
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.768 0.232
G70 Myasthenia gravis and other myoneural disorders
0.231 0.768 0.000
G44.2 Tension-type headache
0.228 0.772 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.773 0.227
G00.9 Bacterial meningitis, unspecified
0.225 0.774 0.000
G83.2 Monoplegia of upper limb
0.219 0.781 0.000
G91.1 Obstructive hydrocephalus
0.216 0.783 0.001
G12.9 Spinal muscular atrophy, unspecified
0.214 0.785 0.001
G12.8 Other spinal muscular atrophies and related syndromes
0.214 0.785 0.001
G12.1 Other inherited spinal muscular atrophy
0.214 0.785 0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.214 0.785 0.001
G91.8 Other hydrocephalus
0.212 0.787 0.001
G91.3 Posttraumatic hydrocephalus, unspecified
0.212 0.787 0.001
G91.0 Communicating hydrocephalus
0.210 0.789 0.001
G02.0 Meningitis in viral diseases classified elsewhere
0.210 0.789 0.001
E13.9 Without complications
0.000 0.789 0.211
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.791 0.209
G83.4 Cauda equina syndrome
0.206 0.794 0.000
G83.5 Locked-in syndrome
0.205 0.795 0.000
G83.3 Monoplegia, unspecified
0.205 0.795 0.000
G83.0 Diplegia of upper limbs
0.205 0.795 0.000
G83.1 Monoplegia of lower limb
0.205 0.795 0.000
G73.7 Myopathy other diseases classified elsewhere
0.204 0.795 0.000
G73.6 Myopathy in metabolic diseases
0.204 0.795 0.000
G73.5 Myopathy in endocrine diseases
0.204 0.795 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.204 0.795 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.204 0.795 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.204 0.795 0.000
G73.1 Eaton-Lambert syndrome
0.204 0.795 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.204 0.795 0.000
G64 Other disorders of peripheral nervous system
0.203 0.797 0.000
G57 Mononeuropathies of lower limb
0.201 0.799 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.200 0.800 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.802 0.198
M13 Other arthritis
0.000 0.802 0.198
M13.0 Polyarthritis, unspecified
0.000 0.804 0.196
M13.00 Polyarthritis, unspecified (Multiple sites)
0.000 0.805 0.195
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.805 0.194
M05 Seropositive rheumatoid arthritis
0.000 0.806 0.194
G83.8 Other specified paralytic syndromes
0.192 0.807 0.000
L40.9 Psoriasis, unspecified
0.191 0.809 0.000
G81 Hemiplegia
0.190 0.810 0.000
G60 Hereditary and idiopathic neuropathy
0.189 0.810 0.000
G57.8 Other mononeuropathies of lower limb
0.187 0.813 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.814 0.186
M06.38 Rheumatoid nodule (Other)
0.000 0.814 0.186
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.814 0.186
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.814 0.186
M06.33 Rheumatoid nodule (Forearm)
0.000 0.814 0.186
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.814 0.186
G57.6 Lesion of plantar nerve
0.186 0.814 0.000
G80.8 Other infantile cerebral palsy
0.185 0.815 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.815 0.185
G47 Sleep disorders
0.182 0.818 0.000
E14 Unspecified diabetes mellitus
0.000 0.819 0.181
G71.0 Muscular dystrophy
0.181 0.819 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.820 0.180
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.820 0.180
G71.9 Primary disorder of muscle, unspecified
0.179 0.820 0.000
G71.8 Other primary disorders of muscles
0.179 0.820 0.000
G71.2 Congenital myopathies
0.179 0.820 0.000
G90.8 Other disorders of autonomic nervous system
0.176 0.823 0.002
G80.2 Infantile hemiplegia
0.176 0.824 0.000
G72 Other myopathies
0.175 0.824 0.001
I83 Varicose veins of lower extremities
0.175 0.825 0.000
G83.9 Paralytic syndrome, unspecified
0.173 0.827 0.000
G90.4 Autonomic dysreflexia
0.171 0.827 0.002
G90.1 Familial dysautonomia [Riley-Day]
0.171 0.827 0.002
E13.8 With unspecified complications
0.000 0.829 0.170
E13.7 With multiple complications
0.000 0.829 0.170
E13.6 With other specified complications
0.000 0.829 0.170
E13.5 With peripheral circulatory complications
0.000 0.829 0.170
E13.4 With neurological complications
0.000 0.829 0.170
E13.3 With ophthalmic complications
0.000 0.829 0.170
E13.2 With renal complications
0.000 0.829 0.170
E13.1 With ketoacidosis
0.000 0.829 0.170
E13.0 With coma
0.000 0.829 0.170
M12 Other specific arthropathies
0.000 0.829 0.170
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.830 0.170
G71.3 Mitochondrial myopathy, not elsewhere classified
0.170 0.830 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.832 0.168
G80.4 Ataxic cerebral palsy
0.168 0.832 0.000
G80.3 Dyskinetic cerebral palsy
0.168 0.832 0.000
G57.1 Meralgia paraesthetica
0.168 0.832 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.165 0.834 0.002
G70.8 Other specified myoneural disorders
0.166 0.834 0.000
G70.2 Congenital and developmental myasthenia
0.166 0.834 0.000
G70.1 Toxic myoneural disorders
0.166 0.834 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.837 0.163
M08 Juvenile arthritis
0.000 0.837 0.163
G57.5 Tarsal tunnel syndrome
0.162 0.838 0.000
G47.8 Other sleep disorders
0.162 0.838 0.000
G70.9 Myoneural disorder, unspecified
0.160 0.839 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.840 0.159
G80.0 Spastic cerebral palsy
0.158 0.841 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.158 0.841 0.000
G82.2 Paraplegia, unspecified
0.155 0.844 0.000
G71.1 Myotonic disorders
0.155 0.845 0.000
G80.1 Spastic diplegia
0.154 0.845 0.000
E14.3 With ophthalmic complications
0.000 0.846 0.154
M13.09 Polyarthritis, unspecified (Site unspecified)
0.000 0.851 0.149
G57.0 Lesion of sciatic nerve
0.149 0.851 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.853 0.146
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.855 0.145
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.144 0.855 0.000
G90.3 Multisystem degeneration
0.142 0.856 0.002
M11 Other crystal arthropathies
0.000 0.856 0.144
G57.4 Lesion of medial popliteal nerve
0.144 0.856 0.000
G57.2 Lesion of femoral nerve
0.144 0.856 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.143 0.857 0.000
E12.9 Without complications
0.000 0.858 0.142
E12.8 With unspecified complications
0.000 0.858 0.142
E12.7 With multiple complications
0.000 0.858 0.142
E12.6 With other specified complications
0.000 0.858 0.142
E12.5 With peripheral circulatory complications
0.000 0.858 0.142
E12.4 With neurological complications
0.000 0.858 0.142
E12.3 With ophthalmic complications
0.000 0.858 0.142
E12.2 With renal complications
0.000 0.858 0.142
E12.1 With ketoacidosis
0.000 0.858 0.142
E12.0 With coma
0.000 0.858 0.142
M13.08 Polyarthritis, unspecified (Other)
0.000 0.859 0.141
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.000 0.859 0.141
M13.06 Polyarthritis, unspecified (Lower leg)
0.000 0.859 0.141
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.000 0.859 0.141
M13.04 Polyarthritis, unspecified (Hand)
0.000 0.859 0.141
M13.03 Polyarthritis, unspecified (Forearm)
0.000 0.859 0.141
M13.02 Polyarthritis, unspecified (Upper arm)
0.000 0.859 0.141
M13.01 Polyarthritis, unspecified (Shoulder region)
0.000 0.859 0.141
E14.1 With ketoacidosis
0.000 0.859 0.141
G52 Disorders of other cranial nerves
0.139 0.861 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.861 0.139
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.861 0.139
M05.2 Rheumatoid vasculitis
0.000 0.861 0.139
M05.1 Rheumatoid lung disease
0.000 0.861 0.139
M05.0 Felty's syndrome
0.000 0.861 0.139
G60.8 Other hereditary and idiopathic neuropathies
0.139 0.861 0.000
G81.1 Spastic hemiplegia
0.138 0.862 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.138 0.862 0.000
G91.2 Normal-pressure hydrocephalus
0.137 0.862 0.001
E14.8 With unspecified complications
0.000 0.862 0.138
G81.0 Flaccid hemiplegia
0.136 0.864 0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.136 0.864 0.000
G60.3 Idiopathic progressive neuropathy
0.136 0.864 0.000
G60.2 Neuropathy in association with hereditary ataxia
0.136 0.864 0.000
G60.1 Refsum's disease
0.136 0.864 0.000
G60.0 Hereditary motor and sensory neuropathy
0.134 0.865 0.000
E14.4 With neurological complications
0.000 0.866 0.134
M13.8 Other specified arthritis
0.000 0.868 0.132
M12.3 Palindromic rheumatism
0.000 0.868 0.132
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.869 0.131
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.869 0.131
E14.7 With multiple complications
0.000 0.870 0.130
E14.6 With other specified complications
0.000 0.870 0.130
E14.2 Withrenal complications
0.000 0.870 0.130
E14.0 With coma
0.000 0.870 0.130
M14.6 Neuropathic arthropathy
0.000 0.874 0.126
G72.3 Periodic paralysis
0.126 0.874 0.001
G72.2 Myopathy due to other toxic agents
0.126 0.874 0.001
G72.1 Alcoholic myopathy
0.126 0.874 0.001
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.126 0.874 0.000
M13.1 Monoarthritis, not elsewhere classified
0.000 0.877 0.123
G57.3 Lesion of lateral popliteal nerve
0.122 0.877 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.877 0.122
M12.5 Traumatic arthropathy
0.000 0.877 0.122
M12.4 Intermittent hydrarthrosis
0.000 0.877 0.122
M12.1 Kaschin-Beck disease
0.000 0.877 0.122
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.877 0.122
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.878 0.122
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.878 0.122
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.878 0.122
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.878 0.122
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.878 0.122
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.878 0.122
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.878 0.122
M10 Gout
0.000 0.878 0.122
G70.0 Myasthenia gravis
0.122 0.878 0.000
M12.2 Villonodular synovitis (pigmented)
0.000 0.879 0.121
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.879 0.121
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.879 0.121
M14.4 Arthropathy in amyloidosis
0.000 0.879 0.121
M14.3 Lipoid dermatoarthritis
0.000 0.879 0.121
M14.2 Diabetic arthropathy
0.000 0.879 0.121
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.879 0.121
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.879 0.121
G72.4 Inflammatory myopathy, not elsewhere classified
0.119 0.880 0.001
E14.5 With peripheral circulatory complications
0.000 0.882 0.118
M08.9 Juvenile arthritis, unspecified
0.000 0.883 0.117
M08.8 Other juvenile arthritis
0.000 0.883 0.117
M08.4 Pauciarticular juvenile arthritis
0.000 0.883 0.117
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.883 0.117
M08.2 Juvenile arthritis with systemic onset
0.000 0.883 0.117
M08.1 Juvenile ankylosing spondylitis
0.000 0.883 0.117
M08.0 Juvenile rheumatoid arthritis
0.000 0.883 0.117
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.883 0.117
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.883 0.117

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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