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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130456
log Bayes Factor = 80.6348
Chromosome 6   position 31,126,252  (GRCh37) Explore rs3130456 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E10 Insulin-dependent diabetes mellitus
0.000 0.019 0.981
E10.9 Without complications
0.000 0.029 0.971
L40.0 Psoriasis vulgaris
0.000 0.037 0.963
E05.9 Thyrotoxicosis, unspecified
0.000 0.046 0.954
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.046 0.954
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.049 0.951
E11.0 With coma
0.000 0.053 0.947
E00-E07 Disorders of thyroid gland
0.000 0.057 0.943
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.069 0.931
E70-E90 Metabolic disorders
0.000 0.075 0.925
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.080 0.920
E78.5 Hyperlipidaemia, unspecified
0.000 0.082 0.918
E78.0 Pure hypercholesterolaemia
0.000 0.107 0.893
E14 Unspecified diabetes mellitus
0.000 0.119 0.881
E11.4 With neurological complications
0.000 0.131 0.869
E10.3 With ophthalmic complications
0.000 0.145 0.855
E78.2 Mixed hyperlipidaemia
0.000 0.164 0.836
L40.1 Generalised pustular psoriasis
0.000 0.166 0.834
E10.2 With renal complications
0.000 0.169 0.831
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.175 0.825
L40.8 Other psoriasis
0.000 0.182 0.818
E78.4 Other hyperlipidaemia
0.000 0.188 0.812
E11.2 With renal complications
0.000 0.195 0.805
E13 Other specified diabetes mellitus
0.000 0.199 0.801
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.201 0.799
K90 Intestinal malabsorption
0.000 0.206 0.794
E79 Disorders of purine and pyrimidine metabolism
0.000 0.231 0.769
L40.4 Guttate psoriasis
0.000 0.235 0.765
E10.8 With unspecified complications
0.000 0.235 0.765
E14.3 With ophthalmic complications
0.000 0.243 0.757
E78.8 Other disorders of lipoprotein metabolism
0.000 0.254 0.746
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.259 0.741
E16 Other disorders of pancreatic internal secretion
0.000 0.267 0.733
E11.5 With peripheral circulatory complications
0.000 0.277 0.723
E14.8 With unspecified complications
0.000 0.282 0.718
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E10.7 With multiple complications
0.000 0.297 0.703
E14.2 Withrenal complications
0.000 0.297 0.703
E78.1 Pure hyperglyceridaemia
0.000 0.301 0.699
E10.1 With ketoacidosis
0.000 0.303 0.697
E85 Amyloidosis
0.000 0.305 0.694
E14.5 With peripheral circulatory complications
0.000 0.308 0.692
E05.5 Thyroid crisis or storm
0.000 0.318 0.682
E05.4 Thyrotoxicosis factitia
0.000 0.318 0.682
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.318 0.682
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.318 0.682
E70 Disorders of aromatic amino-acid metabolism
0.000 0.320 0.680
E88 Other metabolic disorders
0.000 0.321 0.679
E11.7 With multiple complications
0.000 0.322 0.677
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.323 0.676
E00 Congenital iodine-deficiency syndrome
0.000 0.323 0.676
E80.4 Gilbert's syndrome
0.000 0.324 0.676
E13.9 Without complications
0.000 0.324 0.676
E74 Other disorders of carbohydrate metabolism
0.000 0.327 0.673
E78.3 Hyperchylomicronaemia
0.000 0.332 0.668
E16.2 Hypoglycaemia, unspecified
0.000 0.332 0.668
E77 Disorders of glycoprotein metabolism
0.000 0.337 0.663
E76 Disorders of glycosaminoglycan metabolism
0.000 0.337 0.663
E72 Other disorders of amino-acid metabolism
0.000 0.337 0.663
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.337 0.663
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.337 0.663
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.342 0.658
E78.6 Lipoprotein deficiency
0.000 0.343 0.657
E11.1 With ketoacidosis
0.000 0.360 0.640
E11.8 With unspecified complications
0.000 0.360 0.639
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.366 0.633
E80.6 Other disorders of bilirubin metabolism
0.000 0.367 0.633
E14.7 With multiple complications
0.000 0.368 0.631
K90.8 Other intestinal malabsorption
0.000 0.370 0.630
E14.4 With neurological complications
0.000 0.371 0.628
E14.0 With coma
0.000 0.376 0.623
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.379 0.620
E14.6 With other specified complications
0.000 0.384 0.616
E06 Thyroiditis
0.000 0.392 0.608
L40.3 Pustulosis palmaris et plantaris
0.000 0.393 0.607
E15 Nondiabetic hypoglycaemic coma
0.000 0.408 0.591
E84 Cystic fibrosis
0.000 0.415 0.584
E10.0 With coma
0.000 0.416 0.584
E05.8 Other thyrotoxicosis
0.000 0.418 0.582
E80.1 Porphyria cutanea tarda
0.000 0.418 0.582
E85.4 Organ-limited amyloidosis
0.000 0.426 0.574
E13.8 With unspecified complications
0.000 0.426 0.574
E13.7 With multiple complications
0.000 0.426 0.574
E13.6 With other specified complications
0.000 0.426 0.574
E13.5 With peripheral circulatory complications
0.000 0.426 0.574
E13.4 With neurological complications
0.000 0.426 0.574
E13.2 With renal complications
0.000 0.426 0.574
E13.1 With ketoacidosis
0.000 0.426 0.574
E13.0 With coma
0.000 0.426 0.574
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.427 0.573
E80.5 Crigler-Najjar syndrome
0.000 0.427 0.573
E80.3 Defects of catalase and peroxydase
0.000 0.427 0.573
E80.0 Hereditary erythropoietic porphyria
0.000 0.427 0.573
E10.6 With other specified complications
0.000 0.428 0.571
K90.3 Pancreatic steatorrhoea
0.000 0.431 0.569
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.431 0.569
K90.1 Tropical sprue
0.000 0.431 0.569
E80.2 Other porphyria
0.000 0.437 0.563
E88.8 Other specified metabolic disorders
0.000 0.437 0.563
E40-E46 Malnutrition
0.000 0.442 0.558
L40-L45 Papulosquamous disorders
0.000 0.445 0.555
E14.1 With ketoacidosis
0.000 0.447 0.553
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.448 0.551
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.448 0.551
E79.1 Lesch-Nyhan syndrome
0.000 0.448 0.551
E14.9 Without complications
0.000 0.451 0.549
E11.6 With other specified complications
0.000 0.452 0.548
E88.9 Metabolic disorder, unspecified
0.000 0.453 0.547
E13.3 With ophthalmic complications
0.000 0.456 0.544
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.467 0.533
K90.9 Intestinal malabsorption, unspecified
0.000 0.468 0.532
E85.9 Amyloidosis, unspecified
0.000 0.473 0.527
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.474 0.525
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.474 0.525
E16.4 Abnormal secretion of gastrin
0.000 0.474 0.525
E16.3 Increased secretion of glucagon
0.000 0.474 0.525
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.480 0.520
E16.1 Other hypoglycaemia
0.000 0.485 0.515
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E10.5 With peripheral circulatory complications
0.000 0.494 0.506
E70.3 Albinism
0.000 0.495 0.505
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.502 0.498
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.502 0.498
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.502 0.498
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.512 0.488
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.512 0.488
E70.2 Disorders of tyrosine metabolism
0.000 0.512 0.488
E70.1 Other hyperphenylalaninaemias
0.000 0.512 0.488
E70.0 Classical phenylketonuria
0.000 0.512 0.488
E88.2 Lipomatosis, not elsewhere classified
0.000 0.515 0.485
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.515 0.485
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.515 0.485
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.515 0.485
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.515 0.485
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.515 0.485
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.515 0.485
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.515 0.485
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.515 0.485
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.517 0.483
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.517 0.483
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.517 0.483
E74.2 Disorders of galactose metabolism
0.000 0.517 0.483
E74.1 Disorders of fructose metabolism
0.000 0.517 0.483
E85.8 Other amyloidosis
0.000 0.521 0.479
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.523 0.477
E71.3 Disorders of fatty-acid metabolism
0.000 0.524 0.475
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.524 0.475
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.524 0.475
E71.0 Maple-syrup-urine disease
0.000 0.524 0.475
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.524 0.475
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.524 0.475
E72.5 Disorders of glycine metabolism
0.000 0.524 0.475
E72.4 Disorders of ornithine metabolism
0.000 0.524 0.475
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.524 0.475
E72.2 Disorders of urea cycle metabolism
0.000 0.524 0.475
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.524 0.475
E72.0 Disorders of amino-acid transport
0.000 0.524 0.475
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.524 0.475
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.524 0.475
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.524 0.475
E76.2 Other mucopolysaccharidoses
0.000 0.524 0.475
E76.1 Mucopolysaccharidosis, type II
0.000 0.524 0.475
E76.0 Mucopolysaccharidosis, type I
0.000 0.524 0.475
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.524 0.475
E77.8 Other disorders of glycoprotein metabolism
0.000 0.524 0.475
E77.1 Defects in glycoprotein degradation
0.000 0.524 0.475
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.524 0.475
E88.3 Tumour lysis syndrome
0.000 0.533 0.466
E50-E64 Other nutritional deficiencies
0.000 0.538 0.462
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.540 0.460
E75.5 Other lipid storage disorders
0.000 0.543 0.457
E73 Lactose intolerance
0.001 0.544 0.454
E75.6 Lipid storage disorder, unspecified
0.000 0.546 0.454
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.546 0.454
E75.3 Sphingolipidosis, unspecified
0.000 0.546 0.454
E75.1 Other gangliosidosis
0.000 0.546 0.454
E75.0 GM2 gangliosidosis
0.000 0.546 0.454
E10.4 With neurological complications
0.000 0.549 0.451
E74.0 Glycogen storage disease
0.000 0.551 0.449
E07 Other disorders of thyroid
0.000 0.551 0.449
L43 Lichen planus
0.000 0.559 0.441
E06.1 Subacute thyroiditis
0.000 0.562 0.438
E65-E68 Obesity and other hyperalimentation
0.000 0.563 0.437
E06.4 Drug-induced thyroiditis
0.000 0.564 0.436
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.564 0.436
E06.0 Acute thyroiditis
0.000 0.564 0.436
L42 Pityriasis rosea
0.000 0.570 0.430
E06.5 Other chronic thyroiditis
0.000 0.572 0.428
E75.2 Other sphingolipidosis
0.000 0.578 0.422
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.578 0.421
E84.8 Cystic fibrosis with other manifestations
0.000 0.581 0.419
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.581 0.419
E06.9 Thyroiditis, unspecified
0.000 0.581 0.418
E84.9 Cystic fibrosis, unspecified
0.000 0.582 0.418
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.589 0.411
E85.3 Secondary systemic amyloidosis
0.000 0.594 0.406
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.599 0.400
E45 Retarded development following protein-energy malnutrition
0.000 0.599 0.400
E43 Unspecified severe protein-energy malnutrition
0.000 0.599 0.400
E42 Marasmic kwashiorkor
0.000 0.599 0.400
E41 Nutritional marasmus
0.000 0.599 0.400
E40 Kwashiorkor
0.000 0.599 0.400
L44 Other papulosquamous disorders
0.000 0.602 0.398
L41 Parapsoriasis
0.000 0.602 0.398
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.602 0.398
E06.3 Autoimmune thyroiditis
0.000 0.603 0.396
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.604 0.396
L43.9 Lichen planus, unspecified
0.000 0.614 0.386
E03 Other hypothyroidism
0.000 0.632 0.368
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.635 0.365
E61 Deficiency of other nutrient elements
0.000 0.644 0.356
E55 Vitamin D deficiency
0.000 0.648 0.352
E89.3 Postprocedural hypopituitarism
0.000 0.654 0.346
E89.1 Postprocedural hypoinsulinaemia
0.000 0.655 0.345
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.657 0.342
E89.4 Postprocedural ovarian failure
0.000 0.663 0.337
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.668 0.331
E63 Other nutritional deficiencies
0.000 0.668 0.331
E50 Vitamin A deficiency
0.000 0.668 0.331
E60 Dietary zinc deficiency
0.000 0.668 0.331
E59 Dietary selenium deficiency
0.000 0.668 0.331
E52 Niacin deficiency [pellagra]
0.000 0.668 0.331
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.670 0.330
E56 Other vitamin deficiencies
0.000 0.673 0.327
E73.8 Other lactose intolerance
0.001 0.673 0.326
E73.1 Secondary lactase deficiency
0.001 0.673 0.326
E73.0 Congenital lactase deficiency
0.001 0.673 0.326
E07.1 Dyshormogenetic goitre
0.000 0.678 0.322
E07.0 Hypersecretion of calcitonin
0.000 0.678 0.322
E58 Dietary calcium deficiency
0.000 0.680 0.320
E07.8 Other specified disorders of thyroid
0.000 0.683 0.317
L43.3 Subacute (active) lichen planus
0.000 0.683 0.316
L43.2 Lichenoid drug reaction
0.000 0.683 0.316
L43.1 Bullous lichen planus
0.000 0.683 0.316
L43.0 Hypertrophic lichen planus
0.000 0.683 0.316
E67 Other hyperalimentation
0.000 0.687 0.313
E68 Sequelae of hyperalimentation
0.000 0.687 0.313
E89.5 Postprocedural testicular hypofunction
0.000 0.688 0.312
E51 Thiamine deficiency
0.000 0.688 0.312
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.705 0.295
E89.2 Postprocedural hypoparathyroidism
0.000 0.708 0.292
E44.1 Mild protein-energy malnutrition
0.000 0.713 0.287
E44.0 Moderate protein-energy malnutrition
0.000 0.713 0.287
L41.9 Parapsoriasis, unspecified
0.000 0.714 0.285
L41.8 Other parapsoriasis
0.000 0.714 0.285
L41.5 Retiform parapsoriasis
0.000 0.714 0.285
L41.4 Large plaque parapsoriasis
0.000 0.714 0.285
L41.3 Small plaque parapsoriasis
0.000 0.714 0.285
L41.2 Lymphomatoid papulosis
0.000 0.714 0.285
L41.1 Pityriasis lichenoides chronica
0.000 0.714 0.285
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.714 0.285
L44.9 Papulosquamous disorder, unspecified
0.000 0.714 0.285
L44.8 Other specified papulosquamous disorders
0.000 0.714 0.285
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.714 0.285
L44.3 Lichen ruber moniliformis
0.000 0.714 0.285
L44.2 Lichen striatus
0.000 0.714 0.285
L44.1 Lichen nitidus
0.000 0.714 0.285
L44.0 Pityriasis rubra pilaris
0.000 0.714 0.285
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.718 0.282
G56.0 Carpal tunnel syndrome
0.000 0.719 0.281
E54 Ascorbic acid deficiency
0.000 0.720 0.280
E61.2 Magnesium deficiency
0.000 0.721 0.279
E46 Unspecified protein-energy malnutrition
0.000 0.725 0.275
E55.9 Vitamin D deficiency, unspecified
0.000 0.727 0.273
E65 Localised adiposity
0.000 0.732 0.268
E03.5 Myxoedema coma
0.000 0.736 0.264
E03.4 Atrophy of thyroid (acquired)
0.000 0.736 0.264
E03.3 Postinfectious hypothyroidism
0.000 0.736 0.264
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.737 0.263
L43.8 Other lichen planus
0.000 0.741 0.259
E61.1 Iron deficiency
0.000 0.743 0.257
E61.9 Deficiency of nutrient element, unspecified
0.000 0.744 0.256
E61.8 Deficiency of other specified nutrient elements
0.000 0.744 0.256
E61.7 Deficiency of multiple nutrient elements
0.000 0.744 0.256
E61.6 Vanadium deficiency
0.000 0.744 0.256
E61.5 Molybdenum deficiency
0.000 0.744 0.256
E61.4 Chromium deficiency
0.000 0.744 0.256
E61.3 Manganese deficiency
0.000 0.744 0.256
E61.0 Copper deficiency
0.000 0.744 0.256
E55.0 Rickets, active
0.000 0.747 0.253
E03.1 Congenital hypothyroidism without goitre
0.000 0.752 0.248
E03.8 Other specified hypothyroidism
0.000 0.757 0.243
E50.9 Vitamin A deficiency, unspecified
0.000 0.762 0.238
E50.8 Other manifestations of vitamin A deficiency
0.000 0.762 0.238
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.762 0.238
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.762 0.238
E50.5 Vitamin A deficiency with night blindness
0.000 0.762 0.238
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.762 0.238
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.762 0.238
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.762 0.238
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.762 0.238
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.762 0.238
E63.9 Nutritional deficiency, unspecified
0.000 0.762 0.238
E63.8 Other specified nutritional deficiencies
0.000 0.762 0.238
E63.1 Imbalance of constituents of food intake
0.000 0.762 0.238
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.762 0.238
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.762 0.238
E64.8 Sequelae of other nutritional deficiencies
0.000 0.762 0.238
E64.3 Sequelae of rickets
0.000 0.762 0.238
E64.2 Sequelae of vitamin C deficiency
0.000 0.762 0.238
E64.1 Sequelae of vitamin A deficiency
0.000 0.762 0.238
E64.0 Sequelae of protein-energy malnutrition
0.000 0.762 0.238
E56.9 Vitamin deficiency, unspecified
0.000 0.765 0.235
E56.8 Deficiency of other vitamins
0.000 0.765 0.235
E56.0 Deficiency of vitamin E
0.000 0.765 0.235
E56.1 Deficiency of vitamin K
0.000 0.769 0.231
E67.8 Other specified hyperalimentation
0.000 0.775 0.225
E67.3 Hypervitaminosis D
0.000 0.775 0.225
E67.2 Megavitamin-B6 syndrome
0.000 0.775 0.225
E67.1 Hypercarotenaemia
0.000 0.775 0.225
E67.0 Hypervitaminosis A
0.000 0.775 0.225
E51.9 Thiamine deficiency, unspecified
0.000 0.776 0.224
E51.8 Other manifestations of thiamine deficiency
0.000 0.776 0.224
E51.1 Beriberi
0.000 0.776 0.224
E11.3 With ophthalmic complications
0.000 0.788 0.212
E51.2 Wernicke's encephalopathy
0.000 0.796 0.204
E53 Deficiency of other B group vitamins
0.000 0.824 0.176
Z86.1 Personal history of infectious and parasitic diseases
0.000 0.832 0.168
E66 Obesity
0.000 0.834 0.166
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.847 0.153
E89.0 Postprocedural hypothyroidism
0.000 0.867 0.133
G56 Mononeuropathies of upper limb
0.000 0.872 0.128
E53.1 Pyridoxine deficiency
0.000 0.873 0.126
E53.0 Riboflavin deficiency
0.000 0.873 0.126
E73.9 Lactose intolerance, unspecified
0.002 0.880 0.117
E66.1 Drug-induced obesity
0.000 0.881 0.119
G56.9 Mononeuropathy of upper limb, unspecified
0.000 0.889 0.111
E07.9 Disorder of thyroid, unspecified
0.000 0.893 0.107
G56.8 Other mononeuropathies of upper limb
0.000 0.893 0.107
E66.0 Obesity due to excess calories
0.000 0.901 0.099
E53.9 Vitamin B deficiency, unspecified
0.000 0.904 0.095
G56.3 Lesion of radial nerve
0.000 0.905 0.095
G56.4 Causalgia
0.000 0.908 0.091
G56.1 Other lesions of median nerve
0.000 0.912 0.087
E86 Volume depletion
0.000 0.920 0.080
E04 Other non-toxic goitre
0.001 0.938 0.062
K90-K93 Other diseases of the digestive system
0.000 0.941 0.059
E20-E35 Disorders of other endocrine glands
0.000 0.942 0.058
E53.8 Deficiency of other specified B group vitamins
0.000 0.950 0.050
E25 Adrenogenital disorders
0.000 0.953 0.046
E04.8 Other specified non-toxic goitre
0.001 0.955 0.044
E24 Cushing's syndrome
0.000 0.957 0.043
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.958 0.042
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.958 0.041
E32 Diseases of thymus
0.000 0.958 0.041
E30 Disorders of puberty, not elsewhere classified
0.000 0.958 0.041
E23 Hypofunction and other disorders of pituitary gland
0.000 0.960 0.040
E83 Disorders of mineral metabolism
0.001 0.960 0.039
E31 Polyglandular dysfunction
0.000 0.961 0.039
E04.0 Non-toxic diffuse goitre
0.000 0.961 0.038
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.961 0.038
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.962 0.038
E24.0 Pituitary-dependent Cushing's disease
0.000 0.963 0.037
E26 Hyperaldosteronism
0.000 0.963 0.037
E23.7 Disorder of pituitary gland, unspecified
0.000 0.965 0.035
E24.2 Drug-induced Cushing's syndrome
0.000 0.966 0.034
E25.9 Adrenogenital disorder, unspecified
0.000 0.966 0.033
E25.8 Other adrenogenital disorders
0.000 0.966 0.033
E20 Hypoparathyroidism
0.000 0.967 0.033
E22 Hyperfunction of pituitary gland
0.000 0.969 0.031
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.969 0.031
E24.3 Ectopic ACTH syndrome
0.000 0.969 0.031
E24.1 Nelson's syndrome
0.000 0.969 0.031
E29 Testicular dysfunction
0.000 0.969 0.031
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.969 0.030
K93.1 Megacolon in Chagas' disease
0.000 0.969 0.030
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.969 0.030
E23.6 Other disorders of pituitary gland
0.000 0.969 0.031
E66.8 Other obesity
0.000 0.970 0.030
E21.3 Hyperparathyroidism, unspecified
0.000 0.970 0.030
E30.9 Disorder of puberty, unspecified
0.000 0.970 0.030
E30.8 Other disorders of puberty
0.000 0.970 0.030
E30.1 Precocious puberty
0.000 0.970 0.030
E30.0 Delayed puberty
0.000 0.970 0.030
E32.9 Disease of thymus, unspecified
0.000 0.970 0.030
E32.8 Other diseases of thymus
0.000 0.970 0.030
E32.1 Abscess of thymus
0.000 0.970 0.030
E32.0 Persistent hyperplasia of thymus
0.000 0.970 0.030
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.970 0.030
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.970 0.030
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.970 0.030
E21.2 Other hyperparathyroidism
0.000 0.971 0.029
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.971 0.029
E23.1 Drug-induced hypopituitarism
0.000 0.971 0.029
E83.8 Other disorders of mineral metabolism
0.001 0.971 0.028
E83.2 Disorders of zinc metabolism
0.001 0.971 0.028
E83.0 Disorders of copper metabolism
0.001 0.971 0.028
E28 Ovarian dysfunction
0.000 0.971 0.029
E24.8 Other Cushing's syndrome
0.000 0.971 0.029
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.971 0.029
E31.9 Polyglandular dysfunction, unspecified
0.000 0.972 0.028
E31.8 Other polyglandular dysfunction
0.000 0.972 0.028
E31.1 Polyglandular hyperfunction
0.000 0.972 0.028
E34 Other endocrine disorders
0.000 0.972 0.028
E21.4 Other specified disorders of parathyroid gland
0.000 0.972 0.027
E83.9 Disorder of mineral metabolism, unspecified
0.001 0.973 0.026
E26.8 Other hyperaldosteronism
0.000 0.973 0.027
E26.1 Secondary hyperaldosteronism
0.000 0.973 0.027
E26.9 Hyperaldosteronism, unspecified
0.000 0.974 0.026
E31.0 Autoimmune polyglandular failure
0.000 0.974 0.026
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.974 0.026
E22.1 Hyperprolactinaemia
0.000 0.975 0.024
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.976 0.024
E20.8 Other hypoparathyroidism
0.000 0.976 0.024
E20.1 Pseudohypoparathyroidism
0.000 0.976 0.024
E20.0 Idiopathic hypoparathyroidism
0.000 0.976 0.024
E23.0 Hypopituitarism
0.000 0.976 0.024
E26.0 Primary hyperaldosteronism
0.000 0.977 0.023
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.977 0.023
E22.8 Other hyperfunction of pituitary gland
0.000 0.977 0.023
E29.9 Testicular dysfunction, unspecified
0.000 0.978 0.022
E29.8 Other testicular dysfunction
0.000 0.978 0.022
E29.0 Testicular hyperfunction
0.000 0.978 0.022
Z88.4 Personal history of allergy to anaesthetic agent
0.022 0.978 0.000
E34.8 Other specified endocrine disorders
0.000 0.979 0.021
E23.2 Diabetes insipidus
0.000 0.979 0.021
E28.9 Ovarian dysfunction, unspecified
0.000 0.979 0.021
E28.8 Other ovarian dysfunction
0.000 0.979 0.021
E28.1 Androgen excess
0.000 0.979 0.021
E28.0 Oestrogen excess
0.000 0.979 0.021
E34.5 Androgen resistance syndrome
0.000 0.980 0.020
E34.4 Constitutional tall stature
0.000 0.980 0.020
E34.3 Short stature, not elsewhere classified
0.000 0.980 0.020
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.980 0.020
E34.1 Other hypersecretion of intestinal hormones
0.000 0.980 0.020
M07.3 Other psoriatic arthropathies
0.000 0.981 0.019
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.981 0.019
E22.0 Acromegaly and pituitary gigantism
0.000 0.981 0.019
C16.9 Stomach, unspecified
0.000 0.981 0.019
E28.3 Primary ovarian failure
0.000 0.981 0.019
E24.9 Cushing's syndrome, unspecified
0.000 0.981 0.018
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.982 0.018
K91.4 Colostomy and enterostomy malfunction
0.018 0.982 0.000
G56.2 Lesion of ulnar nerve
0.000 0.982 0.018
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.983 0.017
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.984 0.016
E34.9 Endocrine disorder, unspecified
0.000 0.984 0.016
E27 Other disorders of adrenal gland
0.000 0.984 0.016
E20.9 Hypoparathyroidism, unspecified
0.000 0.984 0.015
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.984 0.016
E21.0 Primary hyperparathyroidism
0.000 0.984 0.016
E04.9 Non-toxic goitre, unspecified
0.000 0.985 0.014
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.985 0.014
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.985 0.014
M07.38 Other psoriatic arthropathies (Other)
0.000 0.986 0.014
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.986 0.014
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.986 0.014
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.986 0.014
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.001 0.986 0.014
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.986 0.014
E83.4 Disorders of magnesium metabolism
0.001 0.986 0.013
E83.3 Disorders of phosphorus metabolism
0.001 0.986 0.012
E28.2 Polycystic ovarian syndrome
0.000 0.987 0.012
K91.1 Postgastric surgery syndromes
0.000 0.988 0.012
E27.5 Adrenomedullary hyperfunction
0.000 0.988 0.012
E27.0 Other adrenocortical overactivity
0.000 0.988 0.012
E34.0 Carcinoid syndrome
0.001 0.988 0.011
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.988 0.011
E29.1 Testicular hypofunction
0.000 0.988 0.011
E03.9 Hypothyroidism, unspecified
0.000 0.989 0.011
E27.9 Disorder of adrenal gland, unspecified
0.000 0.989 0.011
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.989 0.011
E83.5 Disorders of calcium metabolism
0.000 0.989 0.011
E04.1 Non-toxic single thyroid nodule
0.000 0.990 0.010
C16 Malignant neoplasm of stomach
0.000 0.990 0.010
K91.2 Postsurgical malabsorption, not elsewhere classified
0.001 0.990 0.009
E27.8 Other specified disorders of adrenal gland
0.000 0.990 0.009
K91.5 Postcholecystectomy syndrome
0.001 0.990 0.009
E27.1 Primary adrenocortical insufficiency
0.000 0.991 0.009
C71.3 Parietal lobe
0.009 0.991 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.991 0.009
C71 Malignant neoplasm of brain
0.009 0.991 0.000
C16.2 Body of stomach
0.000 0.991 0.009
C71.0 Cerebrum, except lobes and ventricles
0.008 0.992 0.000
C71.2 Temporal lobe
0.008 0.992 0.000
C71.9 Brain, unspecified
0.008 0.992 0.000
C16.5 Lesser curvature of stomach, unspecified
0.000 0.992 0.008
C16.1 Fundus of stomach
0.000 0.992 0.008
M07 Psoriatic and enteropathic arthropathies
0.000 0.992 0.008
H16.0 Corneal ulcer
0.008 0.992 0.000
E27.2 Addisonian crisis
0.000 0.993 0.007
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.993 0.007
C16.6 Greater curvature of stomach, unspecified
0.000 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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