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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130482
log Bayes Factor = 110.367
Chromosome 6   position 31,839,782  (GRCh37) Explore rs3130482 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
G35 Multiple sclerosis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.993 0.007 0.000
E10.3 With ophthalmic complications
0.991 0.009 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.986 0.014 0.000
I10 Essential (primary) hypertension
0.000 0.014 0.986
E00-E07 Disorders of thyroid gland
0.985 0.015 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.015 0.985
E10.9 Without complications
0.979 0.021 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.024 0.976
B37.8 Candidiasis of other sites
0.973 0.027 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.031 0.969
E10.2 With renal complications
0.968 0.032 0.000
K90 Intestinal malabsorption
0.956 0.044 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.069 0.931
K90.9 Intestinal malabsorption, unspecified
0.908 0.092 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.117 0.883
E50-E64 Other nutritional deficiencies
0.877 0.123 0.000
E14 Unspecified diabetes mellitus
0.866 0.134 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.138 0.862
E10.4 With neurological complications
0.860 0.140 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.154 0.846
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.822 0.178 0.000
E27.1 Primary adrenocortical insufficiency
0.822 0.178 0.000
E20-E35 Disorders of other endocrine glands
0.817 0.183 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.183 0.817
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.188 0.812
E27 Other disorders of adrenal gland
0.810 0.190 0.000
E10.1 With ketoacidosis
0.808 0.192 0.000
E11 Non-insulin-dependent diabetes mellitus
0.805 0.195 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.795 0.205 0.000
E10.0 With coma
0.787 0.212 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.776 0.224 0.000
B37 Candidiasis
0.775 0.225 0.000
M06 Other rheumatoid arthritis
0.007 0.226 0.767
E10.6 With other specified complications
0.769 0.231 0.000
K90.8 Other intestinal malabsorption
0.767 0.233 0.000
E11.3 With ophthalmic complications
0.757 0.243 0.000
B37.9 Candidiasis, unspecified
0.754 0.246 0.000
E51 Thiamine deficiency
0.745 0.255 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.739 0.261 0.000
E14.1 With ketoacidosis
0.735 0.265 0.000
E10.7 With multiple complications
0.730 0.269 0.000
E14.5 With peripheral circulatory complications
0.722 0.278 0.000
E14.8 With unspecified complications
0.719 0.281 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.285 0.715
E11.6 With other specified complications
0.713 0.287 0.000
E12 Malnutrition-related diabetes mellitus
0.712 0.288 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.706 0.294 0.000
E00 Congenital iodine-deficiency syndrome
0.706 0.294 0.000
G37 Other demyelinating diseases of central nervous system
0.701 0.299 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.302 0.698
E14.6 With other specified complications
0.696 0.304 0.000
E05.8 Other thyrotoxicosis
0.695 0.305 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.692 0.308 0.000
E53 Deficiency of other B group vitamins
0.685 0.315 0.000
K90.3 Pancreatic steatorrhoea
0.685 0.315 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.685 0.315 0.000
K90.1 Tropical sprue
0.685 0.315 0.000
E63 Other nutritional deficiencies
0.678 0.322 0.000
E11.1 With ketoacidosis
0.669 0.331 0.000
M06.3 Rheumatoid nodule
0.003 0.331 0.665
E58 Dietary calcium deficiency
0.668 0.332 0.000
E10.5 With peripheral circulatory complications
0.668 0.332 0.000
E11.4 With neurological complications
0.668 0.332 0.000
E55 Vitamin D deficiency
0.663 0.337 0.000
E14.2 Withrenal complications
0.657 0.343 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.001 0.347 0.651
E51.2 Wernicke's encephalopathy
0.650 0.350 0.000
M05-M14 Inflammatory polyarthropathies
0.062 0.352 0.586
E31 Polyglandular dysfunction
0.647 0.353 0.000
E14.4 With neurological complications
0.645 0.355 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.359 0.641
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.360 0.640
E28 Ovarian dysfunction
0.639 0.361 0.000
M05 Seropositive rheumatoid arthritis
0.028 0.362 0.610
E64 Sequelae of malnutrition and other nutritional deficiencies
0.629 0.371 0.000
E50 Vitamin A deficiency
0.629 0.371 0.000
E60 Dietary zinc deficiency
0.629 0.371 0.000
E59 Dietary selenium deficiency
0.629 0.371 0.000
E54 Ascorbic acid deficiency
0.629 0.371 0.000
E52 Niacin deficiency [pellagra]
0.629 0.371 0.000
E40-E46 Malnutrition
0.624 0.376 0.000
E14.7 With multiple complications
0.621 0.379 0.000
E14.0 With coma
0.621 0.379 0.000
E24 Cushing's syndrome
0.618 0.382 0.000
M06.34 Rheumatoid nodule (Hand)
0.001 0.385 0.614
E61 Deficiency of other nutrient elements
0.600 0.400 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.599 0.401 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.597 0.403 0.000
E20 Hypoparathyroidism
0.594 0.406 0.000
E14.3 With ophthalmic complications
0.592 0.408 0.000
E27.2 Addisonian crisis
0.588 0.411 0.000
E56 Other vitamin deficiencies
0.587 0.413 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.586 0.414 0.000
E30 Disorders of puberty, not elsewhere classified
0.586 0.414 0.000
E32 Diseases of thymus
0.583 0.417 0.000
E53.9 Vitamin B deficiency, unspecified
0.581 0.419 0.000
E27.5 Adrenomedullary hyperfunction
0.581 0.419 0.000
E27.0 Other adrenocortical overactivity
0.581 0.419 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.578 0.421 0.000
E11.7 With multiple complications
0.575 0.425 0.000
B37.1 Pulmonary candidiasis
0.575 0.425 0.000
G36 Other acute disseminated demyelination
0.564 0.435 0.000
B37.2 Candidiasis of skin and nail
0.563 0.437 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.001 0.442 0.558
B37.6 Candidal endocarditis
0.556 0.444 0.000
B37.5 Candidal meningitis
0.556 0.444 0.000
E11.5 With peripheral circulatory complications
0.556 0.444 0.000
E34 Other endocrine disorders
0.555 0.445 0.000
M06.2 Rheumatoid bursitis
0.005 0.445 0.550
M06.1 Adult-onset Still's disease
0.005 0.445 0.550
E06 Thyroiditis
0.551 0.449 0.000
M06.8 Other specified rheumatoid arthritis
0.005 0.460 0.535
E24.0 Pituitary-dependent Cushing's disease
0.539 0.461 0.000
E22 Hyperfunction of pituitary gland
0.537 0.463 0.000
E63.9 Nutritional deficiency, unspecified
0.536 0.464 0.000
E51.9 Thiamine deficiency, unspecified
0.534 0.466 0.000
E51.8 Other manifestations of thiamine deficiency
0.534 0.466 0.000
E51.1 Beriberi
0.534 0.466 0.000
E25 Adrenogenital disorders
0.533 0.466 0.000
E13 Other specified diabetes mellitus
0.531 0.469 0.000
E10.8 With unspecified complications
0.527 0.472 0.000
B37.0 Candidal stomatitis
0.525 0.475 0.000
E31.0 Autoimmune polyglandular failure
0.525 0.475 0.000
E07 Other disorders of thyroid
0.522 0.478 0.000
B37.7 Candidal septicaemia
0.521 0.478 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.001 0.479 0.520
M06.30 Rheumatoid nodule (Multiple sites)
0.002 0.481 0.517
E11.8 With unspecified complications
0.518 0.482 0.000
E28.3 Primary ovarian failure
0.516 0.484 0.000
E27.8 Other specified disorders of adrenal gland
0.511 0.489 0.000
E12.9 Without complications
0.510 0.489 0.000
E12.8 With unspecified complications
0.510 0.489 0.000
E12.7 With multiple complications
0.510 0.489 0.000
E12.6 With other specified complications
0.510 0.489 0.000
E12.5 With peripheral circulatory complications
0.510 0.489 0.000
E12.4 With neurological complications
0.510 0.489 0.000
E12.3 With ophthalmic complications
0.510 0.489 0.000
E12.2 With renal complications
0.510 0.489 0.000
E12.1 With ketoacidosis
0.510 0.489 0.000
E12.0 With coma
0.510 0.489 0.000
E55.9 Vitamin D deficiency, unspecified
0.509 0.491 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.506 0.493 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.506 0.493 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.506 0.493 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.506 0.493 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.506 0.493 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.506 0.493 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.506 0.493 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.506 0.493 0.000
G37.5 Concentric sclerosis [Balo]
0.503 0.497 0.000
G37.4 Subacute necrotising myelitis
0.503 0.497 0.000
G37.2 Central pontine myelinolysis
0.503 0.497 0.000
G37.1 Central demyelination of corpus callosum
0.503 0.497 0.000
G37.0 Diffuse sclerosis
0.503 0.497 0.000
E61.2 Magnesium deficiency
0.495 0.505 0.000
E53.1 Pyridoxine deficiency
0.491 0.508 0.000
E53.0 Riboflavin deficiency
0.491 0.508 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.001 0.509 0.490
M06.32 Rheumatoid nodule (Upper arm)
0.002 0.512 0.486
E63.8 Other specified nutritional deficiencies
0.486 0.513 0.000
E63.1 Imbalance of constituents of food intake
0.486 0.513 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.486 0.513 0.000
B37.4 Candidiasis of other urogenital sites
0.486 0.514 0.000
M06.4 Inflammatory polyarthropathy
0.004 0.514 0.482
M06.39 Rheumatoid nodule (Site unspecified)
0.002 0.521 0.477
M06.38 Rheumatoid nodule (Other)
0.002 0.521 0.477
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.002 0.521 0.477
M06.33 Rheumatoid nodule (Forearm)
0.002 0.521 0.477
M06.31 Rheumatoid nodule (Shoulder region)
0.002 0.521 0.477
M08 Juvenile arthritis
0.042 0.521 0.437
E55.0 Rickets, active
0.475 0.525 0.000
E65-E68 Obesity and other hyperalimentation
0.471 0.529 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.001 0.532 0.467
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.001 0.532 0.467
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.001 0.532 0.467
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.001 0.532 0.467
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.001 0.532 0.467
E22.0 Acromegaly and pituitary gigantism
0.467 0.533 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.045 0.535 0.420
E31.9 Polyglandular dysfunction, unspecified
0.464 0.536 0.000
E31.8 Other polyglandular dysfunction
0.464 0.536 0.000
E31.1 Polyglandular hyperfunction
0.464 0.536 0.000
M35.0 Sicca syndrome [Sjogren]
0.461 0.539 0.000
E28.9 Ovarian dysfunction, unspecified
0.458 0.542 0.000
E28.8 Other ovarian dysfunction
0.458 0.542 0.000
E28.1 Androgen excess
0.458 0.542 0.000
E28.0 Oestrogen excess
0.458 0.542 0.000
E24.8 Other Cushing's syndrome
0.458 0.542 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.020 0.542 0.437
M05.1 Rheumatoid lung disease
0.020 0.542 0.437
M05.0 Felty's syndrome
0.020 0.542 0.437
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.453 0.547 0.000
E28.2 Polycystic ovarian syndrome
0.451 0.549 0.000
E50.9 Vitamin A deficiency, unspecified
0.451 0.549 0.000
E50.8 Other manifestations of vitamin A deficiency
0.451 0.549 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.451 0.549 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.451 0.549 0.000
E50.5 Vitamin A deficiency with night blindness
0.451 0.549 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.451 0.549 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.451 0.549 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.451 0.549 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.451 0.549 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.451 0.549 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.451 0.549 0.000
E64.8 Sequelae of other nutritional deficiencies
0.451 0.549 0.000
E64.3 Sequelae of rickets
0.451 0.549 0.000
E64.2 Sequelae of vitamin C deficiency
0.451 0.549 0.000
E64.1 Sequelae of vitamin A deficiency
0.451 0.549 0.000
E64.0 Sequelae of protein-energy malnutrition
0.451 0.549 0.000
Chapter VI Diseases of the nervous system
0.450 0.550 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.003 0.550 0.447
B35-B49 Mycoses
0.449 0.551 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.447 0.553 0.000
E45 Retarded development following protein-energy malnutrition
0.447 0.553 0.000
E43 Unspecified severe protein-energy malnutrition
0.447 0.553 0.000
E42 Marasmic kwashiorkor
0.447 0.553 0.000
E41 Nutritional marasmus
0.447 0.553 0.000
E40 Kwashiorkor
0.447 0.553 0.000
M05.2 Rheumatoid vasculitis
0.020 0.555 0.425
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.443 0.557 0.000
E24.3 Ectopic ACTH syndrome
0.443 0.557 0.000
E24.1 Nelson's syndrome
0.443 0.557 0.000
M06.0 Seronegative rheumatoid arthritis
0.002 0.559 0.439
K90-K93 Other diseases of the digestive system
0.439 0.561 0.000
M12 Other specific arthropathies
0.041 0.563 0.396
E20.9 Hypoparathyroidism, unspecified
0.435 0.565 0.000
M05.8 Other seropositive rheumatoid arthritis
0.021 0.565 0.414
E61.9 Deficiency of nutrient element, unspecified
0.430 0.570 0.000
E61.8 Deficiency of other specified nutrient elements
0.430 0.570 0.000
E61.7 Deficiency of multiple nutrient elements
0.430 0.570 0.000
E61.6 Vanadium deficiency
0.430 0.570 0.000
E61.5 Molybdenum deficiency
0.430 0.570 0.000
E61.4 Chromium deficiency
0.430 0.570 0.000
E61.3 Manganese deficiency
0.430 0.570 0.000
E61.0 Copper deficiency
0.430 0.570 0.000
E53.8 Deficiency of other specified B group vitamins
0.429 0.571 0.000
E26 Hyperaldosteronism
0.427 0.573 0.000
E20.8 Other hypoparathyroidism
0.426 0.574 0.000
E20.1 Pseudohypoparathyroidism
0.426 0.574 0.000
E20.0 Idiopathic hypoparathyroidism
0.426 0.574 0.000
E56.9 Vitamin deficiency, unspecified
0.421 0.579 0.000
E56.8 Deficiency of other vitamins
0.421 0.579 0.000
E56.0 Deficiency of vitamin E
0.421 0.579 0.000
E30.9 Disorder of puberty, unspecified
0.420 0.580 0.000
E30.8 Other disorders of puberty
0.420 0.580 0.000
E30.1 Precocious puberty
0.420 0.580 0.000
E30.0 Delayed puberty
0.420 0.580 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.420 0.580 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.420 0.580 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.420 0.580 0.000
E32.9 Disease of thymus, unspecified
0.418 0.582 0.000
E32.1 Abscess of thymus
0.418 0.582 0.000
E32.0 Persistent hyperplasia of thymus
0.418 0.582 0.000
E32.8 Other diseases of thymus
0.415 0.585 0.000
E15 Nondiabetic hypoglycaemic coma
0.415 0.585 0.000
E07.8 Other specified disorders of thyroid
0.410 0.590 0.000
E34.0 Carcinoid syndrome
0.409 0.590 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.003 0.592 0.405
E27.4 Other and unspecified adrenocortical insufficiency
0.408 0.592 0.000
G36.9 Acute disseminated demyelination, unspecified
0.405 0.595 0.000
G36.8 Other specified acute disseminated demyelination
0.405 0.595 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.405 0.595 0.000
E04 Other non-toxic goitre
0.402 0.598 0.000
G30-G32 Other degenerative diseases of the nervous system
0.400 0.600 0.000
G36.0 Neuromyelitis optica [Devic]
0.399 0.601 0.000
E34.5 Androgen resistance syndrome
0.398 0.602 0.000
E34.4 Constitutional tall stature
0.398 0.602 0.000
E34.3 Short stature, not elsewhere classified
0.398 0.602 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.398 0.602 0.000
E34.1 Other hypersecretion of intestinal hormones
0.398 0.602 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.004 0.602 0.394
M06.18 Adult-onset Still's disease (Other)
0.004 0.602 0.394
M06.17 Adult-onset Still's disease (Ankle and foot)
0.004 0.602 0.394
M06.16 Adult-onset Still's disease (Lower leg)
0.004 0.602 0.394
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.004 0.602 0.394
M06.14 Adult-onset Still's disease (Hand)
0.004 0.602 0.394
M06.13 Adult-onset Still's disease (Forearm)
0.004 0.602 0.394
M06.12 Adult-onset Still's disease (Upper arm)
0.004 0.602 0.394
M06.11 Adult-onset Still's disease (Shoulder region)
0.004 0.602 0.394
M06.10 Adult-onset Still's disease (Multiple sites)
0.004 0.602 0.394
M06.29 Rheumatoid bursitis (Site unspecified)
0.004 0.602 0.394
M06.28 Rheumatoid bursitis (Other)
0.004 0.602 0.394
M06.27 Rheumatoid bursitis (Ankle and foot)
0.004 0.602 0.394
M06.26 Rheumatoid bursitis (Lower leg)
0.004 0.602 0.394
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.004 0.602 0.394
M06.24 Rheumatoid bursitis (Hand)
0.004 0.602 0.394
M06.23 Rheumatoid bursitis (Forearm)
0.004 0.602 0.394
M06.22 Rheumatoid bursitis (Upper arm)
0.004 0.602 0.394
M06.21 Rheumatoid bursitis (Shoulder region)
0.004 0.602 0.394
M06.20 Rheumatoid bursitis (Multiple sites)
0.004 0.602 0.394
E06.4 Drug-induced thyroiditis
0.395 0.605 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.395 0.605 0.000
E06.1 Subacute thyroiditis
0.395 0.605 0.000
E06.0 Acute thyroiditis
0.395 0.605 0.000
E11.0 With coma
0.395 0.605 0.000
# Top node
0.394 0.606 0.000
E24.2 Drug-induced Cushing's syndrome
0.392 0.608 0.000
Chapter I Certain infectious and parasitic diseases
0.388 0.612 0.000
E06.5 Other chronic thyroiditis
0.387 0.613 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.004 0.613 0.383
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.004 0.613 0.383
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.004 0.613 0.383
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.004 0.613 0.383
M06.84 Other specified rheumatoid arthritis (Hand)
0.004 0.613 0.383
M06.83 Other specified rheumatoid arthritis (Forearm)
0.004 0.613 0.383
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.004 0.613 0.383
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.004 0.613 0.383
Chapter XII Diseases of the skin and subcutaneous tissue
0.387 0.613 0.000
E34.9 Endocrine disorder, unspecified
0.387 0.613 0.000
Chapter XI Diseases of the digestive system
0.387 0.613 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.385 0.615 0.000
E22.8 Other hyperfunction of pituitary gland
0.385 0.615 0.000
D68 Other coagulation defects
0.384 0.616 0.000
E25.9 Adrenogenital disorder, unspecified
0.382 0.617 0.000
E25.8 Other adrenogenital disorders
0.382 0.617 0.000
K70-K77 Diseases of liver
0.381 0.619 0.000
E13.8 With unspecified complications
0.381 0.619 0.000
E13.7 With multiple complications
0.381 0.619 0.000
E13.6 With other specified complications
0.381 0.619 0.000
E13.5 With peripheral circulatory complications
0.381 0.619 0.000
E13.4 With neurological complications
0.381 0.619 0.000
E13.2 With renal complications
0.381 0.619 0.000
E13.1 With ketoacidosis
0.381 0.619 0.000
E13.0 With coma
0.381 0.619 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.380 0.620 0.000
E56.1 Deficiency of vitamin K
0.378 0.621 0.000
L50-L54 Urticaria and erythema
0.377 0.623 0.000
E29 Testicular dysfunction
0.376 0.623 0.001
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.376 0.624 0.000
E07.1 Dyshormogenetic goitre
0.374 0.626 0.000
E07.0 Hypersecretion of calcitonin
0.374 0.626 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.374 0.626 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.373 0.627 0.001
L52 Erythema nodosum
0.371 0.629 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.003 0.631 0.366
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.368 0.632 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.368 0.632 0.000
E34.8 Other specified endocrine disorders
0.366 0.633 0.000
L40-L45 Papulosquamous disorders
0.366 0.634 0.000
E46 Unspecified protein-energy malnutrition
0.364 0.636 0.000
E06.9 Thyroiditis, unspecified
0.364 0.636 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.003 0.637 0.361
G59.0 Diabetic mononeuropathy
0.362 0.638 0.000
L20-L30 Dermatitis and eczema
0.361 0.639 0.000
E13.3 With ophthalmic complications
0.360 0.639 0.000
K70 Alcoholic liver disease
0.359 0.641 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.359 0.641 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.358 0.642 0.000
M08.0 Juvenile rheumatoid arthritis
0.027 0.642 0.331
G62 Other polyneuropathies
0.357 0.642 0.000
D68.0 Von Willebrand's disease
0.352 0.648 0.000
E24.9 Cushing's syndrome, unspecified
0.352 0.648 0.000
D68.9 Coagulation defect, unspecified
0.351 0.649 0.000
K75 Other inflammatory liver diseases
0.351 0.649 0.000
L10-L14 Bullous disorders
0.349 0.651 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.003 0.651 0.345
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.003 0.651 0.345
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.003 0.651 0.345
M06.44 Inflammatory polyarthropathy (Hand)
0.003 0.651 0.345
M06.43 Inflammatory polyarthropathy (Forearm)
0.003 0.651 0.345
M06.42 Inflammatory polyarthropathy (Upper arm)
0.003 0.651 0.345
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.003 0.651 0.345
B36 Other superficial mycoses
0.347 0.653 0.000
K70.3 Alcoholic cirrhosis of liver
0.347 0.653 0.000
L40 Psoriasis
0.347 0.653 0.000
L40.5 Arthropathic psoriasis
0.346 0.654 0.000
D68.5 Primary Thrombophilia
0.346 0.654 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.002 0.654 0.344
B25-B34 Other viral diseases
0.345 0.655 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.004 0.655 0.341
G62.9 Polyneuropathy, unspecified
0.344 0.656 0.000
K35-K38 Diseases of appendix
0.344 0.656 0.000
M08.9 Juvenile arthritis, unspecified
0.030 0.656 0.314
M08.8 Other juvenile arthritis
0.030 0.656 0.314
M08.4 Pauciarticular juvenile arthritis
0.030 0.656 0.314
M08.3 Juvenile polyarthritis (seronegative)
0.030 0.656 0.314
M08.2 Juvenile arthritis with systemic onset
0.030 0.656 0.314
M08.1 Juvenile ankylosing spondylitis
0.030 0.656 0.314
K75.4 Autoimmune hepatitis
0.341 0.659 0.000
K73 Chronic hepatitis, not elsewhere classified
0.340 0.660 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.339 0.661 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.339 0.661 0.000
E67 Other hyperalimentation
0.338 0.662 0.000
E68 Sequelae of hyperalimentation
0.338 0.662 0.000
B25 Cytomegaloviral disease
0.336 0.664 0.000
L27 Dermatitis due to substances taken internally
0.335 0.665 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.013 0.666 0.321
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.032 0.666 0.301
M09.2 Juvenile arthritis in ulcerative colitis
0.032 0.666 0.301
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.032 0.666 0.301
M09.0 Juvenile arthritis in psoriasis
0.032 0.666 0.301
B25.9 Cytomegaloviral disease, unspecified
0.331 0.669 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.002 0.669 0.329
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.330 0.670 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.329 0.671 0.000
L21 Seborrhoeic dermatitis
0.329 0.671 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.328 0.671 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.003 0.672 0.326
M05.09 Felty's syndrome (Site unspecified)
0.015 0.672 0.314
M05.08 Felty's syndrome (Other)
0.015 0.672 0.314
M05.07 Felty's syndrome (Ankle and foot)
0.015 0.672 0.314
M05.06 Felty's syndrome (Lower leg)
0.015 0.672 0.314
M05.05 Felty's syndrome (Pelvic region and thigh)
0.015 0.672 0.314
M05.04 Felty's syndrome (Hand)
0.015 0.672 0.314
M05.03 Felty's syndrome (Forearm)
0.015 0.672 0.314
M05.02 Felty's syndrome (Upper arm)
0.015 0.672 0.314
M05.01 Felty's syndrome (Shoulder region)
0.015 0.672 0.314
M05.00 Felty's syndrome (Multiple sites)
0.015 0.672 0.314
M05.19 Rheumatoid lung disease (Site unspecified)
0.015 0.672 0.314
M05.18 Rheumatoid lung disease (Other)
0.015 0.672 0.314
M05.17 Rheumatoid lung disease (Ankle and foot)
0.015 0.672 0.314
M05.16 Rheumatoid lung disease (Lower leg)
0.015 0.672 0.314
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.015 0.672 0.314
M05.14 Rheumatoid lung disease (Hand)
0.015 0.672 0.314
M05.13 Rheumatoid lung disease (Forearm)
0.015 0.672 0.314
M05.12 Rheumatoid lung disease (Upper arm)
0.015 0.672 0.314
M05.11 Rheumatoid lung disease (Shoulder region)
0.015 0.672 0.314
M05.10 Rheumatoid lung disease (Multiple sites)
0.015 0.672 0.314
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.015 0.672 0.314
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.015 0.672 0.314
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.015 0.672 0.314
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.015 0.672 0.314
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.015 0.672 0.314
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.015 0.672 0.314
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.015 0.672 0.314
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.015 0.672 0.314
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.015 0.672 0.314
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.015 0.672 0.314
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.327 0.673 0.000
M07 Psoriatic and enteropathic arthropathies
0.071 0.674 0.255
D68.6 Other Thrombophilia
0.325 0.675 0.000
K70.4 Alcoholic hepatic failure
0.325 0.675 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.324 0.676 0.000
E27.9 Disorder of adrenal gland, unspecified
0.322 0.677 0.001
M06.04 Seronegative rheumatoid arthritis (Hand)
0.002 0.677 0.321
K75.8 Other specified inflammatory liver diseases
0.323 0.677 0.000
B48 Other mycoses, not elsewhere classified
0.322 0.678 0.000
B47 Mycetoma
0.322 0.678 0.000
B46 Zygomycosis
0.322 0.678 0.000
B45 Cryptococcosis
0.322 0.678 0.000
B43 Chromomycosis and phaeomycotic abscess
0.322 0.678 0.000
B42 Sporotrichosis
0.322 0.678 0.000
B41 Paracoccidioidomycosis
0.322 0.678 0.000
B40 Blastomycosis
0.322 0.678 0.000
B39 Histoplasmosis
0.322 0.678 0.000
B38 Coccidioidomycosis
0.322 0.678 0.000
E44.1 Mild protein-energy malnutrition
0.321 0.679 0.000
E44.0 Moderate protein-energy malnutrition
0.321 0.679 0.000
M05.28 Rheumatoid vasculitis (Other)
0.015 0.681 0.305
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.015 0.681 0.305
M05.26 Rheumatoid vasculitis (Lower leg)
0.015 0.681 0.305
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.015 0.681 0.305
M05.24 Rheumatoid vasculitis (Hand)
0.015 0.681 0.305
M05.23 Rheumatoid vasculitis (Forearm)
0.015 0.681 0.305
M05.22 Rheumatoid vasculitis (Upper arm)
0.015 0.681 0.305
M05.21 Rheumatoid vasculitis (Shoulder region)
0.015 0.681 0.305
M11 Other crystal arthropathies
0.049 0.681 0.270
M12.3 Palindromic rheumatism
0.026 0.681 0.293
K37 Unspecified appendicitis
0.318 0.682 0.000
L13 Other bullous disorders
0.317 0.683 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.002 0.683 0.315
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.002 0.683 0.315
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.002 0.683 0.315
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.002 0.683 0.315
E66 Obesity
0.316 0.684 0.000
B49 Unspecified mycosis
0.315 0.685 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.315 0.685 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.314 0.686 0.000
M12.4 Intermittent hydrarthrosis
0.030 0.686 0.284
M12.1 Kaschin-Beck disease
0.030 0.686 0.284
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.030 0.686 0.284
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.002 0.687 0.312
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.015 0.688 0.297
M05.88 Other seropositive rheumatoid arthritis (Other)
0.015 0.688 0.297
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.015 0.688 0.297
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.015 0.688 0.297
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.015 0.688 0.297
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.015 0.688 0.297
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.015 0.688 0.297
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.015 0.688 0.297
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.015 0.688 0.297
E78.0 Pure hypercholesterolaemia
0.000 0.688 0.312
B90-B94 Sequelae of infectious and parasitic diseases
0.309 0.691 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.029 0.691 0.279
E70-E90 Metabolic disorders
0.308 0.692 0.000
E26.8 Other hyperaldosteronism
0.306 0.694 0.000
E26.1 Secondary hyperaldosteronism
0.306 0.694 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.306 0.694 0.000
K73.9 Chronic hepatitis, unspecified
0.306 0.694 0.000
L21.9 Seborrhoeic dermatitis, unspecified
0.306 0.694 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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