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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130502
log Bayes Factor = 57.1225
Chromosome 6   position 31,136,666  (GRCh37) Explore rs3130502 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.006 0.994
E05.9 Thyrotoxicosis, unspecified
0.000 0.007 0.993
E78.0 Pure hypercholesterolaemia
0.000 0.010 0.990
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.012 0.988
E70-E90 Metabolic disorders
0.000 0.015 0.985
G35 Multiple sclerosis
0.976 0.024 0.000
E14 Unspecified diabetes mellitus
0.000 0.037 0.963
L40 Psoriasis
0.000 0.037 0.963
L40.5 Arthropathic psoriasis
0.000 0.090 0.910
E11.0 With coma
0.000 0.110 0.890
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.124 0.876
E14.3 With ophthalmic complications
0.000 0.130 0.870
E14.9 Without complications
0.000 0.139 0.861
E78.8 Other disorders of lipoprotein metabolism
0.000 0.143 0.857
E10.3 With ophthalmic complications
0.000 0.149 0.851
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.163 0.837
E07 Other disorders of thyroid
0.000 0.163 0.837
E78.2 Mixed hyperlipidaemia
0.000 0.177 0.823
L40.0 Psoriasis vulgaris
0.000 0.183 0.817
L40.8 Other psoriasis
0.000 0.193 0.807
E03.8 Other specified hypothyroidism
0.000 0.194 0.806
E11.1 With ketoacidosis
0.000 0.206 0.794
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.224 0.776
E79 Disorders of purine and pyrimidine metabolism
0.000 0.230 0.770
E74 Other disorders of carbohydrate metabolism
0.000 0.233 0.767
E11.2 With renal complications
0.000 0.240 0.760
E14.5 With peripheral circulatory complications
0.000 0.240 0.760
E10.6 With other specified complications
0.000 0.245 0.755
E80.4 Gilbert's syndrome
0.000 0.245 0.755
E10.8 With unspecified complications
0.000 0.249 0.751
E78.1 Pure hyperglyceridaemia
0.000 0.252 0.748
E13 Other specified diabetes mellitus
0.000 0.262 0.738
E40-E46 Malnutrition
0.000 0.264 0.736
L40.1 Generalised pustular psoriasis
0.000 0.265 0.735
E07.9 Disorder of thyroid, unspecified
0.000 0.268 0.732
G35-G37 Demyelinating diseases of the central nervous system
0.728 0.272 0.000
K90 Intestinal malabsorption
0.000 0.280 0.720
E14.4 With neurological complications
0.000 0.282 0.718
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.716
E10.1 With ketoacidosis
0.000 0.287 0.713
E05.5 Thyroid crisis or storm
0.000 0.287 0.712
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.712
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.712
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.712
E78.4 Other hyperlipidaemia
0.000 0.288 0.712
E10.0 With coma
0.000 0.290 0.710
E78.6 Lipoprotein deficiency
0.000 0.290 0.709
E78.3 Hyperchylomicronaemia
0.000 0.292 0.708
E77 Disorders of glycoprotein metabolism
0.000 0.294 0.706
E76 Disorders of glycosaminoglycan metabolism
0.000 0.294 0.706
E72 Other disorders of amino-acid metabolism
0.000 0.294 0.706
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.294 0.706
E70 Disorders of aromatic amino-acid metabolism
0.000 0.294 0.706
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.294 0.706
E14.6 With other specified complications
0.000 0.305 0.695
E14.1 With ketoacidosis
0.000 0.306 0.693
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.309 0.691
E14.7 With multiple complications
0.000 0.310 0.690
E14.0 With coma
0.000 0.310 0.690
L40.2 Acrodermatitis continua
0.000 0.310 0.690
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.310 0.690
E80.6 Other disorders of bilirubin metabolism
0.000 0.311 0.689
L40.4 Guttate psoriasis
0.000 0.316 0.684
E14.2 Withrenal complications
0.000 0.317 0.683
E78.5 Hyperlipidaemia, unspecified
0.000 0.318 0.682
E84 Cystic fibrosis
0.000 0.320 0.680
E83 Disorders of mineral metabolism
0.644 0.322 0.034
E80.2 Other porphyria
0.000 0.331 0.669
G37 Other demyelinating diseases of central nervous system
0.666 0.334 0.000
E14.8 With unspecified complications
0.000 0.351 0.649
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.355 0.645
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.358 0.642
E03.1 Congenital hypothyroidism without goitre
0.000 0.366 0.634
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.372 0.628
E80.5 Crigler-Najjar syndrome
0.000 0.372 0.628
E80.3 Defects of catalase and peroxydase
0.000 0.372 0.628
E80.0 Hereditary erythropoietic porphyria
0.000 0.372 0.628
E11.8 With unspecified complications
0.000 0.373 0.627
C83.3 Large cell (diffuse)
0.000 0.375 0.625
E80.1 Porphyria cutanea tarda
0.000 0.377 0.623
E10.2 With renal complications
0.000 0.383 0.617
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.383 0.617
E16 Other disorders of pancreatic internal secretion
0.000 0.385 0.615
G37.9 Demyelinating disease of central nervous system, unspecified
0.609 0.391 0.000
E10.5 With peripheral circulatory complications
0.000 0.392 0.608
E07.1 Dyshormogenetic goitre
0.000 0.400 0.600
E07.0 Hypersecretion of calcitonin
0.000 0.400 0.600
L40-L45 Papulosquamous disorders
0.000 0.402 0.598
E05.8 Other thyrotoxicosis
0.000 0.408 0.591
E88 Other metabolic disorders
0.000 0.417 0.583
K90.9 Intestinal malabsorption, unspecified
0.000 0.426 0.574
E07.8 Other specified disorders of thyroid
0.000 0.427 0.573
E13.9 Without complications
0.000 0.429 0.571
E73 Lactose intolerance
0.000 0.429 0.570
L40.3 Pustulosis palmaris et plantaris
0.000 0.434 0.566
E83.3 Disorders of phosphorus metabolism
0.549 0.441 0.010
G36 Other acute disseminated demyelination
0.559 0.441 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.444 0.556
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.448 0.552
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.448 0.552
E79.1 Lesch-Nyhan syndrome
0.000 0.448 0.552
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.450 0.550
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.450 0.550
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.450 0.550
E74.2 Disorders of galactose metabolism
0.000 0.450 0.550
E74.1 Disorders of fructose metabolism
0.000 0.450 0.550
E46 Unspecified protein-energy malnutrition
0.000 0.453 0.547
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.461 0.539
G37.8 Other specified demyelinating diseases of central nervous system
0.536 0.464 0.000
E13.8 With unspecified complications
0.000 0.471 0.529
E13.7 With multiple complications
0.000 0.471 0.529
E13.6 With other specified complications
0.000 0.471 0.529
E13.5 With peripheral circulatory complications
0.000 0.471 0.529
E13.4 With neurological complications
0.000 0.471 0.529
E13.2 With renal complications
0.000 0.471 0.529
E13.1 With ketoacidosis
0.000 0.471 0.529
E13.0 With coma
0.000 0.471 0.529
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.472 0.528
E45 Retarded development following protein-energy malnutrition
0.000 0.472 0.528
E43 Unspecified severe protein-energy malnutrition
0.000 0.472 0.528
E42 Marasmic kwashiorkor
0.000 0.472 0.528
E41 Nutritional marasmus
0.000 0.472 0.528
E40 Kwashiorkor
0.000 0.472 0.528
E83.9 Disorder of mineral metabolism, unspecified
0.499 0.479 0.022
K90.3 Pancreatic steatorrhoea
0.000 0.483 0.516
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.483 0.516
K90.1 Tropical sprue
0.000 0.483 0.516
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.001 0.484 0.515
E11.5 With peripheral circulatory complications
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E10.4 With neurological complications
0.000 0.489 0.511
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.489 0.511
C83 Diffuse non-Hodgkin's lymphoma
0.003 0.491 0.506
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.494 0.506
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.494 0.506
E70.3 Albinism
0.000 0.494 0.506
E70.2 Disorders of tyrosine metabolism
0.000 0.494 0.506
E70.1 Other hyperphenylalaninaemias
0.000 0.494 0.506
E70.0 Classical phenylketonuria
0.000 0.494 0.506
E71.3 Disorders of fatty-acid metabolism
0.000 0.494 0.506
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.494 0.506
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.494 0.506
E71.0 Maple-syrup-urine disease
0.000 0.494 0.506
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.494 0.506
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.494 0.506
E72.5 Disorders of glycine metabolism
0.000 0.494 0.506
E72.4 Disorders of ornithine metabolism
0.000 0.494 0.506
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.494 0.506
E72.2 Disorders of urea cycle metabolism
0.000 0.494 0.506
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.494 0.506
E72.0 Disorders of amino-acid transport
0.000 0.494 0.506
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.494 0.506
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.494 0.506
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.494 0.506
E76.2 Other mucopolysaccharidoses
0.000 0.494 0.506
E76.1 Mucopolysaccharidosis, type II
0.000 0.494 0.506
E76.0 Mucopolysaccharidosis, type I
0.000 0.494 0.506
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.494 0.506
E77.8 Other disorders of glycoprotein metabolism
0.000 0.494 0.506
E77.1 Defects in glycoprotein degradation
0.000 0.494 0.506
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.494 0.506
C85.1 B-cell lymphoma, unspecified
0.000 0.494 0.506
L43 Lichen planus
0.000 0.497 0.503
E13.3 With ophthalmic complications
0.000 0.498 0.502
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.004 0.501 0.494
K90.8 Other intestinal malabsorption
0.000 0.504 0.495
E75.6 Lipid storage disorder, unspecified
0.000 0.505 0.494
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.505 0.494
E75.3 Sphingolipidosis, unspecified
0.000 0.505 0.494
E75.2 Other sphingolipidosis
0.000 0.505 0.494
E75.1 Other gangliosidosis
0.000 0.505 0.494
E75.0 GM2 gangliosidosis
0.000 0.505 0.494
E74.0 Glycogen storage disease
0.000 0.511 0.489
E84.8 Cystic fibrosis with other manifestations
0.000 0.512 0.487
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.512 0.487
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.512 0.487
E83.8 Other disorders of mineral metabolism
0.462 0.514 0.024
E83.2 Disorders of zinc metabolism
0.462 0.514 0.024
E83.0 Disorders of copper metabolism
0.462 0.514 0.024
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.001 0.515 0.483
E11.6 With other specified complications
0.000 0.519 0.481
E16.1 Other hypoglycaemia
0.000 0.519 0.481
E75.5 Other lipid storage disorders
0.000 0.521 0.478
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.522 0.478
G37.5 Concentric sclerosis [Balo]
0.478 0.522 0.000
G37.4 Subacute necrotising myelitis
0.478 0.522 0.000
G37.2 Central pontine myelinolysis
0.478 0.522 0.000
G37.1 Central demyelination of corpus callosum
0.478 0.522 0.000
G37.0 Diffuse sclerosis
0.478 0.522 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.523 0.477
L42 Pityriasis rosea
0.000 0.533 0.467
E84.9 Cystic fibrosis, unspecified
0.000 0.538 0.461
L43.9 Lichen planus, unspecified
0.000 0.542 0.458
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.456 0.543 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.544 0.456
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.558 0.442
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.559 0.441
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.559 0.441
E16.4 Abnormal secretion of gastrin
0.000 0.559 0.441
E16.3 Increased secretion of glucagon
0.000 0.559 0.441
G36.0 Neuromyelitis optica [Devic]
0.437 0.563 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.565 0.435
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.566 0.434
L44 Other papulosquamous disorders
0.000 0.571 0.429
L41 Parapsoriasis
0.000 0.571 0.429
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.571 0.429
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.572 0.428
E11.4 With neurological complications
0.000 0.580 0.420
E88.9 Metabolic disorder, unspecified
0.000 0.582 0.418
E88.8 Other specified metabolic disorders
0.000 0.582 0.418
E88.3 Tumour lysis syndrome
0.000 0.587 0.413
E89.4 Postprocedural ovarian failure
0.000 0.589 0.410
E73.8 Other lactose intolerance
0.000 0.591 0.409
E73.1 Secondary lactase deficiency
0.000 0.591 0.409
E73.0 Congenital lactase deficiency
0.000 0.591 0.409
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.596 0.404
E85 Amyloidosis
0.001 0.599 0.400
G36.9 Acute disseminated demyelination, unspecified
0.401 0.599 0.000
G36.8 Other specified acute disseminated demyelination
0.401 0.599 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.401 0.599 0.000
E06 Thyroiditis
0.000 0.603 0.397
C83.7 Burkitt's tumour
0.002 0.607 0.391
C82.2 Large cell, follicular
0.001 0.609 0.391
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.613 0.387
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.613 0.387
E89.5 Postprocedural testicular hypofunction
0.000 0.613 0.387
E89.1 Postprocedural hypoinsulinaemia
0.000 0.613 0.387
E44.1 Mild protein-energy malnutrition
0.000 0.621 0.378
E44.0 Moderate protein-energy malnutrition
0.000 0.621 0.378
C82.3 Follicular lymphoma grade IIIa
0.001 0.624 0.375
E89.3 Postprocedural hypopituitarism
0.000 0.628 0.372
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.001 0.630 0.369
C85.0 Lymphosarcoma
0.001 0.630 0.369
C81 Hodgkin's disease
0.002 0.632 0.365
C83.6 Undifferentiated (diffuse)
0.002 0.635 0.363
C83.5 Lymphoblastic (diffuse)
0.002 0.635 0.363
C83.4 Immunoblastic (diffuse)
0.002 0.635 0.363
C83.2 Mixed small and large cell (diffuse)
0.002 0.635 0.363
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.635 0.364
E83.4 Disorders of magnesium metabolism
0.352 0.636 0.012
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.639 0.361
L43.3 Subacute (active) lichen planus
0.000 0.639 0.360
L43.2 Lichenoid drug reaction
0.000 0.639 0.360
L43.1 Bullous lichen planus
0.000 0.639 0.360
L43.0 Hypertrophic lichen planus
0.000 0.639 0.360
M06.9 Rheumatoid arthritis, unspecified
0.000 0.641 0.359
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.641 0.358
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.003 0.642 0.354
C86 Other specified types of T/NK-cell lymphoma
0.003 0.642 0.354
C84 Peripheral and cutaneous T-cell lymphomas
0.003 0.644 0.353
E65-E68 Obesity and other hyperalimentation
0.000 0.649 0.351
C82.6 Cutaneous follicle centre lymphoma
0.001 0.652 0.347
C82.5 Diffuse follicle centre lymphoma
0.001 0.652 0.347
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.001 0.653 0.346
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.002 0.662 0.336
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.664 0.336
C82.0 Small cleaved cell, follicular
0.001 0.668 0.331
C94 Other leukaemias of specified cell type
0.004 0.673 0.324
E89.2 Postprocedural hypoparathyroidism
0.000 0.673 0.327
C82.4 Follicular lymphoma grade IIIb
0.001 0.678 0.321
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.685 0.315
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.686 0.314
C81.9 Hodgkin's disease, unspecified
0.001 0.686 0.314
E83.5 Disorders of calcium metabolism
0.304 0.692 0.003
L41.9 Parapsoriasis, unspecified
0.000 0.692 0.307
L41.8 Other parapsoriasis
0.000 0.692 0.307
L41.5 Retiform parapsoriasis
0.000 0.692 0.307
L41.4 Large plaque parapsoriasis
0.000 0.692 0.307
L41.3 Small plaque parapsoriasis
0.000 0.692 0.307
L41.2 Lymphomatoid papulosis
0.000 0.692 0.307
L41.1 Pityriasis lichenoides chronica
0.000 0.692 0.307
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.692 0.307
L44.9 Papulosquamous disorder, unspecified
0.000 0.692 0.307
L44.8 Other specified papulosquamous disorders
0.000 0.692 0.307
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.692 0.307
L44.3 Lichen ruber moniliformis
0.000 0.692 0.307
L44.2 Lichen striatus
0.000 0.692 0.307
L44.1 Lichen nitidus
0.000 0.692 0.307
L44.0 Pityriasis rubra pilaris
0.000 0.692 0.307
C93 Monocytic leukaemia
0.004 0.696 0.301
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.698 0.302
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.698 0.302
C83.1 Small cleaved cell (diffuse)
0.003 0.708 0.290
L43.8 Other lichen planus
0.000 0.712 0.288
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.712 0.287
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.712 0.287
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.712 0.287
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.714 0.286
E06.5 Other chronic thyroiditis
0.000 0.715 0.285
E06.4 Drug-induced thyroiditis
0.000 0.715 0.285
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.715 0.285
E06.0 Acute thyroiditis
0.000 0.715 0.285
E20-E35 Disorders of other endocrine glands
0.000 0.717 0.283
C88 Malignant immunoproliferative diseases
0.004 0.719 0.277
E73.9 Lactose intolerance, unspecified
0.001 0.726 0.274
E85.8 Other amyloidosis
0.001 0.727 0.273
C91 Lymphoid leukaemia
0.003 0.729 0.269
E06.1 Subacute thyroiditis
0.000 0.729 0.271
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.731 0.269
E50-E64 Other nutritional deficiencies
0.000 0.732 0.268
C84.5 Other and unspecified T-cell lymphomas
0.002 0.735 0.264
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.002 0.736 0.262
C81.3 Lymphocytic depletion
0.002 0.736 0.262
C81.2 Mixed cellularity
0.002 0.736 0.262
C81.7 Other Hodgkin's disease
0.002 0.739 0.259
E85.9 Amyloidosis, unspecified
0.001 0.742 0.257
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.003 0.743 0.254
C86.5 Angioimmunoblastic T-cell lymphoma
0.003 0.743 0.254
C86.4 Blastic NK-cell lymphoma
0.003 0.743 0.254
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.003 0.743 0.254
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.003 0.743 0.254
C86.1 Hepatosplenic T-cell lymphoma
0.003 0.743 0.254
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.003 0.743 0.254
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.003 0.743 0.254
C96.8 Histiocytic sarcoma
0.003 0.743 0.254
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.003 0.743 0.254
C96.6 Unifocal Langerhans-cell histiocytosis
0.003 0.743 0.254
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.003 0.743 0.254
C96.4 Sarcoma of dendritic cells (accessory cells)
0.003 0.743 0.254
C96.3 True histiocytic lymphoma
0.003 0.743 0.254
C96.2 Malignant mast cell tumour
0.003 0.743 0.254
C96.1 Malignant histiocytosis
0.003 0.743 0.254
C96.0 Letterer-Siwe disease
0.003 0.743 0.254
C84.0 Mycosis fungoides
0.002 0.744 0.254
C84.9 Mature T/NK-cell lymphoma, unspecified
0.002 0.745 0.253
C84.8 Cutaneous T-cell lymphoma, unspecified
0.002 0.745 0.253
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.002 0.745 0.253
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.002 0.745 0.253
C84.3 Lymphoepithelioid lymphoma
0.002 0.745 0.253
C84.2 T-zone lymphoma
0.002 0.745 0.253
C84.1 Sezary's diease
0.002 0.745 0.253
C81.0 Lymphocytic predominance
0.002 0.746 0.252
E67 Other hyperalimentation
0.000 0.748 0.252
E68 Sequelae of hyperalimentation
0.000 0.748 0.252
C82.1 Mixed small cleaved and large cell, follicular
0.001 0.750 0.248
E28 Ovarian dysfunction
0.000 0.752 0.248
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.753 0.247
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.754 0.245
C91.9 Lymphoid leukaemia, unspecified
0.001 0.757 0.241
C84.4 Peripheral T-cell lymphoma
0.002 0.758 0.240
C95 Leukaemia of unspecified cell type
0.004 0.763 0.233
C94.7 Other specified leukaemias
0.003 0.765 0.232
C94.5 Acute myelofibrosis
0.003 0.765 0.232
C94.4 Acute panmyelosis
0.003 0.765 0.232
C94.3 Mast cell leukaemia
0.003 0.765 0.232
C94.2 Acute megakaryoblastic leukaemia
0.003 0.765 0.232
C94.1 Chronic erythraemia
0.003 0.765 0.232
C94.0 Acute erythraemia and erythroleukaemia
0.003 0.765 0.232
E85.4 Organ-limited amyloidosis
0.001 0.768 0.232
E28.2 Polycystic ovarian syndrome
0.000 0.768 0.232
E24 Cushing's syndrome
0.000 0.774 0.226
E23 Hypofunction and other disorders of pituitary gland
0.000 0.776 0.224
E11.3 With ophthalmic complications
0.000 0.779 0.221
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.781 0.219
C93.9 Monocytic leukaemia, unspecified
0.003 0.781 0.216
C93.7 Other monocytic leukaemia
0.003 0.781 0.216
C93.3 Juvenile myelomonocytic leukaemia
0.003 0.781 0.216
C93.2 Subacute monocytic leukaemia
0.003 0.781 0.216
C93.0 Acute monocytic leukaemia
0.003 0.781 0.216
K91.4 Colostomy and enterostomy malfunction
0.217 0.783 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.003 0.795 0.203
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.003 0.795 0.201
E85.3 Secondary systemic amyloidosis
0.001 0.796 0.203
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.797 0.203
E32 Diseases of thymus
0.000 0.797 0.203
E31 Polyglandular dysfunction
0.000 0.797 0.203
E30 Disorders of puberty, not elsewhere classified
0.000 0.797 0.203
E25 Adrenogenital disorders
0.000 0.797 0.203
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.003 0.797 0.200
C81.1 Nodular sclerosis
0.002 0.798 0.200
C88.9 Malignant immunoproliferative disease, unspecified
0.003 0.798 0.199
C88.7 Other malignant immunoproliferative diseases
0.003 0.798 0.199
C88.3 Immunoproliferative small intestinal disease
0.003 0.798 0.199
C88.2 Gamma heavy chain disease
0.003 0.798 0.199
C88.1 Alpha heavy chain disease
0.003 0.798 0.199
C83.0 Small cell (diffuse)
0.003 0.799 0.198
E65 Localised adiposity
0.000 0.800 0.200
E06.3 Autoimmune thyroiditis
0.000 0.800 0.199
C91.5 Adult T-cell leukaemia
0.002 0.804 0.194
E21.3 Hyperparathyroidism, unspecified
0.000 0.804 0.196
C91.8 Mature B-cell leukaemia Burkitt-type
0.002 0.805 0.193
C91.7 Other lymphoid leukaemia
0.002 0.805 0.193
C91.6 Prolymphocytic leukaemia of T-cell type
0.002 0.805 0.193
C91.3 Prolymphocytic leukaemia
0.002 0.805 0.193
C91.2 Subacute lymphocytic leukaemia
0.002 0.805 0.193
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.808 0.192
E63 Other nutritional deficiencies
0.000 0.808 0.192
E50 Vitamin A deficiency
0.000 0.808 0.192
E60 Dietary zinc deficiency
0.000 0.808 0.192
E59 Dietary selenium deficiency
0.000 0.808 0.192
E54 Ascorbic acid deficiency
0.000 0.808 0.192
E52 Niacin deficiency [pellagra]
0.000 0.808 0.192
E56 Other vitamin deficiencies
0.000 0.812 0.188
E58 Dietary calcium deficiency
0.000 0.814 0.185
C92 Myeloid leukaemia
0.004 0.815 0.181
E23.7 Disorder of pituitary gland, unspecified
0.000 0.817 0.183
E67.8 Other specified hyperalimentation
0.000 0.819 0.181
E67.3 Hypervitaminosis D
0.000 0.819 0.181
E67.2 Megavitamin-B6 syndrome
0.000 0.819 0.181
E67.1 Hypercarotenaemia
0.000 0.819 0.181
E67.0 Hypervitaminosis A
0.000 0.819 0.181
E24.2 Drug-induced Cushing's syndrome
0.000 0.819 0.181
E26 Hyperaldosteronism
0.000 0.819 0.180
E51 Thiamine deficiency
0.000 0.820 0.180
E06.9 Thyroiditis, unspecified
0.001 0.821 0.178
E28.9 Ovarian dysfunction, unspecified
0.000 0.822 0.178
E28.8 Other ovarian dysfunction
0.000 0.822 0.178
E28.1 Androgen excess
0.000 0.822 0.178
E28.0 Oestrogen excess
0.000 0.822 0.178
E23.2 Diabetes insipidus
0.000 0.822 0.177
C91.0 Acute lymphoblastic leukaemia
0.002 0.826 0.172
E20 Hypoparathyroidism
0.000 0.827 0.173
C95.7 Other leukaemia of unspecified cell type
0.003 0.830 0.167
C95.2 Subacute leukaemia of unspecified cell type
0.003 0.830 0.167
E24.9 Cushing's syndrome, unspecified
0.000 0.832 0.168
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.833 0.167
E61 Deficiency of other nutrient elements
0.000 0.833 0.167
C93.1 Chronic monocytic leukaemia
0.004 0.835 0.162
M06 Other rheumatoid arthritis
0.000 0.837 0.163
E24.8 Other Cushing's syndrome
0.000 0.838 0.162
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.838 0.162
E24.3 Ectopic ACTH syndrome
0.000 0.838 0.162
E24.1 Nelson's syndrome
0.000 0.838 0.162
E24.0 Pituitary-dependent Cushing's disease
0.000 0.838 0.162
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.839 0.161
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.839 0.161
E23.1 Drug-induced hypopituitarism
0.000 0.839 0.161
E21.4 Other specified disorders of parathyroid gland
0.000 0.843 0.157
E21.2 Other hyperparathyroidism
0.000 0.843 0.157
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.844 0.156
E29 Testicular dysfunction
0.000 0.846 0.154
E23.6 Other disorders of pituitary gland
0.000 0.847 0.153
C95.1 Chronic leukaemia of unspecified cell type
0.004 0.848 0.148
E89.0 Postprocedural hypothyroidism
0.000 0.851 0.149
C95.9 Leukaemia, unspecified
0.003 0.851 0.145
E23.0 Hypopituitarism
0.000 0.853 0.147
E25.9 Adrenogenital disorder, unspecified
0.000 0.854 0.146
E25.8 Other adrenogenital disorders
0.000 0.854 0.146
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.854 0.146
E30.9 Disorder of puberty, unspecified
0.000 0.854 0.146
E30.8 Other disorders of puberty
0.000 0.854 0.146
E30.1 Precocious puberty
0.000 0.854 0.146
E30.0 Delayed puberty
0.000 0.854 0.146
E31.9 Polyglandular dysfunction, unspecified
0.000 0.854 0.146
E31.8 Other polyglandular dysfunction
0.000 0.854 0.146
E31.1 Polyglandular hyperfunction
0.000 0.854 0.146
E31.0 Autoimmune polyglandular failure
0.000 0.854 0.146
E32.9 Disease of thymus, unspecified
0.000 0.854 0.146
E32.8 Other diseases of thymus
0.000 0.854 0.146
E32.1 Abscess of thymus
0.000 0.854 0.146
E32.0 Persistent hyperplasia of thymus
0.000 0.854 0.146
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.854 0.146
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.854 0.146
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.854 0.146
C90 Multiple myeloma and malignant plasma cell neoplasms
0.057 0.857 0.087
E55 Vitamin D deficiency
0.000 0.857 0.143
K51.9 Ulcerative colitis, unspecified
0.142 0.858 0.000
M06.3 Rheumatoid nodule
0.000 0.859 0.141
E50.9 Vitamin A deficiency, unspecified
0.000 0.862 0.138
E50.8 Other manifestations of vitamin A deficiency
0.000 0.862 0.138
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.862 0.138
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.862 0.138
E50.5 Vitamin A deficiency with night blindness
0.000 0.862 0.138

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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