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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130521
log Bayes Factor = 77.1922
Chromosome 6   position 31,196,376  (GRCh37) Explore rs3130521 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.005 0.995
E14 Unspecified diabetes mellitus
0.000 0.006 0.994
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.007 0.993
E05.9 Thyrotoxicosis, unspecified
0.000 0.007 0.993
E00-E07 Disorders of thyroid gland
0.000 0.007 0.993
E11.0 With coma
0.000 0.013 0.987
E70-E90 Metabolic disorders
0.000 0.016 0.984
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.016 0.984
E78.0 Pure hypercholesterolaemia
0.000 0.021 0.979
E13 Other specified diabetes mellitus
0.000 0.040 0.960
E10.1 With ketoacidosis
0.000 0.041 0.959
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.064 0.936
E14.9 Without complications
0.000 0.064 0.936
E78.2 Mixed hyperlipidaemia
0.000 0.070 0.930
E13.9 Without complications
0.000 0.070 0.930
L40-L45 Papulosquamous disorders
0.000 0.073 0.927
E11.4 With neurological complications
0.000 0.074 0.926
L43 Lichen planus
0.000 0.088 0.912
L43.9 Lichen planus, unspecified
0.000 0.102 0.898
E10.2 With renal complications
0.000 0.103 0.897
K90 Intestinal malabsorption
0.000 0.109 0.891
L40.0 Psoriasis vulgaris
0.000 0.113 0.887
E11.1 With ketoacidosis
0.000 0.122 0.878
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.122 0.878
E10.4 With neurological complications
0.000 0.123 0.877
E14.3 With ophthalmic complications
0.000 0.127 0.872
E11.5 With peripheral circulatory complications
0.000 0.128 0.872
E40-E46 Malnutrition
0.000 0.140 0.860
E88 Other metabolic disorders
0.000 0.142 0.858
E10.8 With unspecified complications
0.000 0.149 0.851
E14.8 With unspecified complications
0.000 0.156 0.844
E78.5 Hyperlipidaemia, unspecified
0.000 0.162 0.838
E16.1 Other hypoglycaemia
0.000 0.166 0.834
E14.2 Withrenal complications
0.000 0.167 0.833
E78.4 Other hyperlipidaemia
0.000 0.186 0.814
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.190 0.810
E89.2 Postprocedural hypoparathyroidism
0.000 0.200 0.800
E79 Disorders of purine and pyrimidine metabolism
0.000 0.216 0.784
E14.1 With ketoacidosis
0.000 0.217 0.783
E11.2 With renal complications
0.000 0.223 0.777
K90.9 Intestinal malabsorption, unspecified
0.000 0.225 0.775
E10.0 With coma
0.000 0.228 0.772
E14.5 With peripheral circulatory complications
0.000 0.231 0.768
E14.6 With other specified complications
0.000 0.235 0.765
E85 Amyloidosis
0.000 0.236 0.764
E11.6 With other specified complications
0.000 0.239 0.761
E46 Unspecified protein-energy malnutrition
0.000 0.240 0.760
E89.3 Postprocedural hypopituitarism
0.000 0.240 0.760
E06 Thyroiditis
0.000 0.246 0.753
L40.8 Other psoriasis
0.000 0.252 0.748
E11.8 With unspecified complications
0.000 0.254 0.746
E05.8 Other thyrotoxicosis
0.000 0.258 0.742
E78.8 Other disorders of lipoprotein metabolism
0.000 0.259 0.741
E10.6 With other specified complications
0.000 0.264 0.736
E74 Other disorders of carbohydrate metabolism
0.000 0.265 0.735
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.266 0.734
L43.8 Other lichen planus
0.000 0.274 0.726
L40.1 Generalised pustular psoriasis
0.000 0.277 0.723
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.716
E16.3 Increased secretion of glucagon
0.000 0.283 0.716
L40.4 Guttate psoriasis
0.000 0.283 0.716
L40.2 Acrodermatitis continua
0.000 0.283 0.716
E14.7 With multiple complications
0.000 0.287 0.713
E14.0 With coma
0.000 0.287 0.713
E05.5 Thyroid crisis or storm
0.000 0.288 0.712
E05.4 Thyrotoxicosis factitia
0.000 0.288 0.712
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.288 0.712
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.288 0.712
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.288 0.712
E00 Congenital iodine-deficiency syndrome
0.000 0.288 0.712
E10.5 With peripheral circulatory complications
0.000 0.289 0.711
E13.3 With ophthalmic complications
0.000 0.292 0.708
E77 Disorders of glycoprotein metabolism
0.000 0.294 0.706
E76 Disorders of glycosaminoglycan metabolism
0.000 0.294 0.706
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.294 0.706
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.294 0.706
E78.3 Hyperchylomicronaemia
0.000 0.294 0.706
K90.8 Other intestinal malabsorption
0.000 0.299 0.701
E78.6 Lipoprotein deficiency
0.000 0.301 0.699
E72 Other disorders of amino-acid metabolism
0.000 0.304 0.696
E13.8 With unspecified complications
0.000 0.311 0.688
E13.7 With multiple complications
0.000 0.311 0.688
E13.6 With other specified complications
0.000 0.311 0.688
E13.5 With peripheral circulatory complications
0.000 0.311 0.688
E13.4 With neurological complications
0.000 0.311 0.688
E13.2 With renal complications
0.000 0.311 0.688
E13.1 With ketoacidosis
0.000 0.311 0.688
E13.0 With coma
0.000 0.311 0.688
E88.9 Metabolic disorder, unspecified
0.000 0.313 0.687
E70 Disorders of aromatic amino-acid metabolism
0.000 0.313 0.687
E89.4 Postprocedural ovarian failure
0.000 0.323 0.677
E14.4 With neurological complications
0.000 0.324 0.676
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.326 0.674
E78.1 Pure hyperglyceridaemia
0.000 0.330 0.669
E88.2 Lipomatosis, not elsewhere classified
0.000 0.331 0.669
L42 Pityriasis rosea
0.000 0.332 0.668
E84 Cystic fibrosis
0.000 0.335 0.665
L44 Other papulosquamous disorders
0.000 0.335 0.665
L41 Parapsoriasis
0.000 0.335 0.665
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.335 0.665
L40.3 Pustulosis palmaris et plantaris
0.000 0.337 0.663
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.339 0.661
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.341 0.659
E50-E64 Other nutritional deficiencies
0.000 0.344 0.656
L43.3 Subacute (active) lichen planus
0.000 0.346 0.654
L43.2 Lichenoid drug reaction
0.000 0.346 0.654
L43.1 Bullous lichen planus
0.000 0.346 0.654
L43.0 Hypertrophic lichen planus
0.000 0.346 0.654
E06.9 Thyroiditis, unspecified
0.000 0.346 0.654
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.359 0.641
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.359 0.641
K90.3 Pancreatic steatorrhoea
0.000 0.361 0.639
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.361 0.639
K90.1 Tropical sprue
0.000 0.361 0.639
E88.8 Other specified metabolic disorders
0.000 0.363 0.637
E85.4 Organ-limited amyloidosis
0.000 0.367 0.632
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.371 0.629
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.371 0.629
E89.5 Postprocedural testicular hypofunction
0.000 0.371 0.629
E89.1 Postprocedural hypoinsulinaemia
0.000 0.371 0.629
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.383 0.617
E45 Retarded development following protein-energy malnutrition
0.000 0.383 0.617
E43 Unspecified severe protein-energy malnutrition
0.000 0.383 0.617
E42 Marasmic kwashiorkor
0.000 0.383 0.617
E41 Nutritional marasmus
0.000 0.383 0.617
E40 Kwashiorkor
0.000 0.383 0.617
E88.3 Tumour lysis syndrome
0.000 0.398 0.602
E11.3 With ophthalmic complications
0.000 0.401 0.599
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.409 0.591
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.420 0.579
E85.9 Amyloidosis, unspecified
0.000 0.431 0.569
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.438 0.562
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.438 0.562
E79.1 Lesch-Nyhan syndrome
0.000 0.438 0.562
E65-E68 Obesity and other hyperalimentation
0.000 0.441 0.559
E06.5 Other chronic thyroiditis
0.000 0.449 0.551
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.452 0.548
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.452 0.548
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.452 0.548
E06.4 Drug-induced thyroiditis
0.000 0.460 0.540
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.460 0.540
E06.1 Subacute thyroiditis
0.000 0.460 0.540
E06.0 Acute thyroiditis
0.000 0.460 0.540
E55 Vitamin D deficiency
0.000 0.460 0.540
E85.8 Other amyloidosis
0.000 0.467 0.532
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.470 0.530
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.473 0.527
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.473 0.527
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.473 0.527
E74.2 Disorders of galactose metabolism
0.000 0.473 0.527
E74.1 Disorders of fructose metabolism
0.000 0.473 0.527
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.477 0.523
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.490 0.510
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.490 0.510
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.490 0.510
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.490 0.510
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.490 0.510
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.490 0.510
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.490 0.510
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.490 0.510
E71.3 Disorders of fatty-acid metabolism
0.000 0.494 0.506
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.494 0.506
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.494 0.506
E71.0 Maple-syrup-urine disease
0.000 0.494 0.506
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.494 0.506
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.494 0.506
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.494 0.506
E76.2 Other mucopolysaccharidoses
0.000 0.494 0.506
E76.1 Mucopolysaccharidosis, type II
0.000 0.494 0.506
E76.0 Mucopolysaccharidosis, type I
0.000 0.494 0.506
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.494 0.506
E77.8 Other disorders of glycoprotein metabolism
0.000 0.494 0.506
E77.1 Defects in glycoprotein degradation
0.000 0.494 0.506
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.494 0.506
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.501 0.499
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.501 0.499
E72.5 Disorders of glycine metabolism
0.000 0.501 0.499
E72.4 Disorders of ornithine metabolism
0.000 0.501 0.499
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.501 0.499
E72.2 Disorders of urea cycle metabolism
0.000 0.501 0.499
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.501 0.499
E74.0 Glycogen storage disease
0.000 0.503 0.497
E85.3 Secondary systemic amyloidosis
0.000 0.504 0.496
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.507 0.493
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.507 0.493
E70.2 Disorders of tyrosine metabolism
0.000 0.507 0.493
E70.1 Other hyperphenylalaninaemias
0.000 0.507 0.493
E70.0 Classical phenylketonuria
0.000 0.507 0.493
E72.0 Disorders of amino-acid transport
0.000 0.511 0.489
E84.9 Cystic fibrosis, unspecified
0.000 0.511 0.489
E75.6 Lipid storage disorder, unspecified
0.000 0.516 0.483
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.516 0.483
E75.3 Sphingolipidosis, unspecified
0.000 0.516 0.483
E75.1 Other gangliosidosis
0.000 0.516 0.483
E75.0 GM2 gangliosidosis
0.000 0.516 0.483
E61 Deficiency of other nutrient elements
0.000 0.517 0.483
E51 Thiamine deficiency
0.000 0.521 0.479
E56 Other vitamin deficiencies
0.000 0.522 0.478
E84.8 Cystic fibrosis with other manifestations
0.000 0.523 0.477
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.523 0.477
L41.9 Parapsoriasis, unspecified
0.000 0.523 0.476
L41.8 Other parapsoriasis
0.000 0.523 0.476
L41.5 Retiform parapsoriasis
0.000 0.523 0.476
L41.4 Large plaque parapsoriasis
0.000 0.523 0.476
L41.3 Small plaque parapsoriasis
0.000 0.523 0.476
L41.2 Lymphomatoid papulosis
0.000 0.523 0.476
L41.1 Pityriasis lichenoides chronica
0.000 0.523 0.476
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.523 0.476
L44.9 Papulosquamous disorder, unspecified
0.000 0.523 0.476
L44.8 Other specified papulosquamous disorders
0.000 0.523 0.476
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.523 0.476
L44.3 Lichen ruber moniliformis
0.000 0.523 0.476
L44.2 Lichen striatus
0.000 0.523 0.476
L44.1 Lichen nitidus
0.000 0.523 0.476
L44.0 Pityriasis rubra pilaris
0.000 0.523 0.476
E75.2 Other sphingolipidosis
0.000 0.525 0.475
E70.3 Albinism
0.000 0.526 0.474
E73 Lactose intolerance
0.002 0.528 0.470
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.530 0.470
E63 Other nutritional deficiencies
0.000 0.530 0.470
E50 Vitamin A deficiency
0.000 0.530 0.470
E60 Dietary zinc deficiency
0.000 0.530 0.470
E59 Dietary selenium deficiency
0.000 0.530 0.470
E52 Niacin deficiency [pellagra]
0.000 0.530 0.470
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.534 0.466
E75.5 Other lipid storage disorders
0.000 0.538 0.461
E55.9 Vitamin D deficiency, unspecified
0.000 0.543 0.457
E03 Other hypothyroidism
0.066 0.548 0.386
E58 Dietary calcium deficiency
0.000 0.551 0.449
E54 Ascorbic acid deficiency
0.000 0.557 0.443
E44.1 Mild protein-energy malnutrition
0.000 0.558 0.442
E44.0 Moderate protein-energy malnutrition
0.000 0.558 0.442
E07 Other disorders of thyroid
0.000 0.559 0.441
E65 Localised adiposity
0.000 0.576 0.424
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.579 0.420
E67 Other hyperalimentation
0.000 0.599 0.401
E68 Sequelae of hyperalimentation
0.000 0.599 0.401
E80.1 Porphyria cutanea tarda
0.000 0.601 0.399
E55.0 Rickets, active
0.000 0.613 0.387
E80.6 Other disorders of bilirubin metabolism
0.000 0.619 0.381
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.620 0.380
E80.5 Crigler-Najjar syndrome
0.000 0.620 0.380
E80.3 Defects of catalase and peroxydase
0.000 0.620 0.380
E80.0 Hereditary erythropoietic porphyria
0.000 0.620 0.380
E06.3 Autoimmune thyroiditis
0.000 0.631 0.369
E61.2 Magnesium deficiency
0.000 0.633 0.367
C83.3 Large cell (diffuse)
0.000 0.634 0.366
E51.2 Wernicke's encephalopathy
0.000 0.648 0.352
E80.2 Other porphyria
0.000 0.650 0.350
E56.1 Deficiency of vitamin K
0.000 0.650 0.350
E61.9 Deficiency of nutrient element, unspecified
0.000 0.654 0.346
E61.8 Deficiency of other specified nutrient elements
0.000 0.654 0.346
E61.7 Deficiency of multiple nutrient elements
0.000 0.654 0.346
E61.6 Vanadium deficiency
0.000 0.654 0.346
E61.5 Molybdenum deficiency
0.000 0.654 0.346
E61.4 Chromium deficiency
0.000 0.654 0.346
E61.3 Manganese deficiency
0.000 0.654 0.346
E61.0 Copper deficiency
0.000 0.654 0.346
E51.9 Thiamine deficiency, unspecified
0.000 0.656 0.343
E51.8 Other manifestations of thiamine deficiency
0.000 0.656 0.343
E51.1 Beriberi
0.000 0.656 0.343
E56.9 Vitamin deficiency, unspecified
0.000 0.657 0.342
E56.8 Deficiency of other vitamins
0.000 0.657 0.342
E56.0 Deficiency of vitamin E
0.000 0.657 0.342
E73.8 Other lactose intolerance
0.001 0.661 0.337
E73.1 Secondary lactase deficiency
0.001 0.661 0.337
E73.0 Congenital lactase deficiency
0.001 0.661 0.337
E50.9 Vitamin A deficiency, unspecified
0.000 0.663 0.337
E50.8 Other manifestations of vitamin A deficiency
0.000 0.663 0.337
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.663 0.337
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.663 0.337
E50.5 Vitamin A deficiency with night blindness
0.000 0.663 0.337
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.663 0.337
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.663 0.337
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.663 0.337
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.663 0.337
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.663 0.337
E63.9 Nutritional deficiency, unspecified
0.000 0.663 0.337
E63.8 Other specified nutritional deficiencies
0.000 0.663 0.337
E63.1 Imbalance of constituents of food intake
0.000 0.663 0.337
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.663 0.337
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.663 0.337
E64.8 Sequelae of other nutritional deficiencies
0.000 0.663 0.337
E64.3 Sequelae of rickets
0.000 0.663 0.337
E64.2 Sequelae of vitamin C deficiency
0.000 0.663 0.337
E64.1 Sequelae of vitamin A deficiency
0.000 0.663 0.337
E64.0 Sequelae of protein-energy malnutrition
0.000 0.663 0.337
E61.1 Iron deficiency
0.000 0.663 0.337
E03.1 Congenital hypothyroidism without goitre
0.044 0.674 0.282
E03.5 Myxoedema coma
0.047 0.676 0.277
E03.4 Atrophy of thyroid (acquired)
0.047 0.676 0.277
E03.3 Postinfectious hypothyroidism
0.047 0.676 0.277
E03.0 Congenital hypothyroidism with diffuse goitre
0.047 0.676 0.277
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.040 0.678 0.282
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.679 0.321
E07.1 Dyshormogenetic goitre
0.000 0.684 0.316
E07.0 Hypersecretion of calcitonin
0.000 0.684 0.316
E53 Deficiency of other B group vitamins
0.000 0.704 0.296
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.706 0.294
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.708 0.292
E67.8 Other specified hyperalimentation
0.000 0.712 0.287
E67.3 Hypervitaminosis D
0.000 0.712 0.287
E67.2 Megavitamin-B6 syndrome
0.000 0.712 0.287
E67.1 Hypercarotenaemia
0.000 0.712 0.287
E67.0 Hypervitaminosis A
0.000 0.712 0.287
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.715 0.285
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.719 0.281
E03.8 Other specified hypothyroidism
0.043 0.719 0.238
E07.8 Other specified disorders of thyroid
0.000 0.719 0.280
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.722 0.278
C85.1 B-cell lymphoma, unspecified
0.000 0.738 0.262
E86 Volume depletion
0.000 0.739 0.261
C83.0 Small cell (diffuse)
0.000 0.742 0.258
C83.7 Burkitt's tumour
0.000 0.743 0.257
Z86.1 Personal history of infectious and parasitic diseases
0.000 0.749 0.251
C82.2 Large cell, follicular
0.000 0.766 0.234
C83.6 Undifferentiated (diffuse)
0.000 0.770 0.230
C83.4 Immunoblastic (diffuse)
0.000 0.770 0.230
C83.2 Mixed small and large cell (diffuse)
0.000 0.770 0.230
C83.1 Small cleaved cell (diffuse)
0.000 0.770 0.230
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.774 0.226
C82.0 Small cleaved cell, follicular
0.000 0.776 0.224
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.779 0.220
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.783 0.217
E03.9 Hypothyroidism, unspecified
0.217 0.783 0.000
E80.4 Gilbert's syndrome
0.000 0.784 0.216
E53.1 Pyridoxine deficiency
0.000 0.788 0.212
E53.0 Riboflavin deficiency
0.000 0.788 0.212
C88 Malignant immunoproliferative diseases
0.000 0.790 0.210
C85.0 Lymphosarcoma
0.000 0.791 0.209
C82.4 Follicular lymphoma grade IIIb
0.000 0.795 0.205
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.796 0.204
E89.0 Postprocedural hypothyroidism
0.000 0.796 0.204
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.796 0.204
C82.6 Cutaneous follicle centre lymphoma
0.000 0.798 0.202
C82.5 Diffuse follicle centre lymphoma
0.000 0.798 0.202
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.799 0.201
E53.9 Vitamin B deficiency, unspecified
0.000 0.807 0.193
C86 Other specified types of T/NK-cell lymphoma
0.000 0.808 0.192
C83.5 Lymphoblastic (diffuse)
0.000 0.808 0.192
E66 Obesity
0.000 0.813 0.187
K90-K93 Other diseases of the digestive system
0.000 0.813 0.187
C94 Other leukaemias of specified cell type
0.000 0.814 0.186
C93 Monocytic leukaemia
0.000 0.814 0.186
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.823 0.177
C95 Leukaemia of unspecified cell type
0.000 0.832 0.168
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.834 0.166
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.836 0.164
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.836 0.164
C81 Hodgkin's disease
0.000 0.836 0.164
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.849 0.150
C88.7 Other malignant immunoproliferative diseases
0.000 0.849 0.150
C88.3 Immunoproliferative small intestinal disease
0.000 0.849 0.150
C88.2 Gamma heavy chain disease
0.000 0.849 0.150
C88.1 Alpha heavy chain disease
0.000 0.849 0.150
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.853 0.146
C96.8 Histiocytic sarcoma
0.000 0.853 0.146
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.853 0.146
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.853 0.146
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.853 0.146
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.853 0.146
C96.3 True histiocytic lymphoma
0.000 0.853 0.146
C96.2 Malignant mast cell tumour
0.000 0.853 0.146
C96.1 Malignant histiocytosis
0.000 0.853 0.146
C96.0 Letterer-Siwe disease
0.000 0.853 0.146
C82.3 Follicular lymphoma grade IIIa
0.000 0.855 0.145
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.858 0.142
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.860 0.140
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.862 0.138
C86.4 Blastic NK-cell lymphoma
0.000 0.862 0.138
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.862 0.138
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.862 0.138
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.862 0.138
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.862 0.138
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.863 0.137
E66.1 Drug-induced obesity
0.000 0.866 0.134
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.866 0.134
C94.7 Other specified leukaemias
0.000 0.866 0.134
C94.5 Acute myelofibrosis
0.000 0.866 0.134
C94.4 Acute panmyelosis
0.000 0.866 0.134
C94.3 Mast cell leukaemia
0.000 0.866 0.134
C94.2 Acute megakaryoblastic leukaemia
0.000 0.866 0.134
C94.1 Chronic erythraemia
0.000 0.866 0.134
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.866 0.134
C93.9 Monocytic leukaemia, unspecified
0.000 0.866 0.133
C93.7 Other monocytic leukaemia
0.000 0.866 0.133
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.866 0.133
C93.2 Subacute monocytic leukaemia
0.000 0.866 0.133
C93.0 Acute monocytic leukaemia
0.000 0.866 0.133
E07.9 Disorder of thyroid, unspecified
0.000 0.867 0.133
C84.0 Mycosis fungoides
0.000 0.869 0.131
E66.0 Obesity due to excess calories
0.000 0.869 0.130
C81.9 Hodgkin's disease, unspecified
0.000 0.871 0.129
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.873 0.127
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.873 0.127
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.873 0.127
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.873 0.127
C84.3 Lymphoepithelioid lymphoma
0.000 0.873 0.127
C84.2 T-zone lymphoma
0.000 0.873 0.127
C84.1 Sezary's diease
0.000 0.873 0.127
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.874 0.126
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.874 0.126
C81.0 Lymphocytic predominance
0.000 0.876 0.123
C95.7 Other leukaemia of unspecified cell type
0.000 0.879 0.120
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.879 0.120
C81.7 Other Hodgkin's disease
0.000 0.882 0.118
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.882 0.118
C81.3 Lymphocytic depletion
0.000 0.882 0.118
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.883 0.117
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.884 0.116
C84.5 Other and unspecified T-cell lymphomas
0.000 0.885 0.115
C93.1 Chronic monocytic leukaemia
0.000 0.885 0.115
E20-E35 Disorders of other endocrine glands
0.000 0.886 0.114
K91.1 Postgastric surgery syndromes
0.000 0.890 0.110
C84.4 Peripheral T-cell lymphoma
0.000 0.890 0.110
C95.9 Leukaemia, unspecified
0.000 0.892 0.108
K91.5 Postcholecystectomy syndrome
0.000 0.893 0.106
E73.9 Lactose intolerance, unspecified
0.004 0.894 0.101
K31.8 Other specified diseases of stomach and duodenum
0.000 0.895 0.105
C81.2 Mixed cellularity
0.000 0.895 0.104
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.899 0.101
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.904 0.096
K93.1 Megacolon in Chagas' disease
0.000 0.904 0.096
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.904 0.096
C95.0 Acute leukaemia of unspecified cell type
0.000 0.906 0.093
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.910 0.090
E24 Cushing's syndrome
0.000 0.911 0.089
E25 Adrenogenital disorders
0.000 0.911 0.089
E53.8 Deficiency of other specified B group vitamins
0.000 0.914 0.086
C91 Lymphoid leukaemia
0.000 0.914 0.086
E22 Hyperfunction of pituitary gland
0.000 0.914 0.086
J33.9 Nasal polyp, unspecified
0.000 0.914 0.086
E04 Other non-toxic goitre
0.001 0.916 0.083
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.918 0.082
E32 Diseases of thymus
0.000 0.918 0.082
E30 Disorders of puberty, not elsewhere classified
0.000 0.918 0.082
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.921 0.079
E24.0 Pituitary-dependent Cushing's disease
0.000 0.922 0.078
E31 Polyglandular dysfunction
0.000 0.924 0.076
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.924 0.076
E26 Hyperaldosteronism
0.000 0.928 0.072
E22.1 Hyperprolactinaemia
0.000 0.929 0.071
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.929 0.071
C91.9 Lymphoid leukaemia, unspecified
0.000 0.930 0.070
E23 Hypofunction and other disorders of pituitary gland
0.000 0.931 0.069
E20 Hypoparathyroidism
0.000 0.931 0.069
I25.2 Old myocardial infarction
0.000 0.935 0.065
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.936 0.064
E22.0 Acromegaly and pituitary gigantism
0.000 0.936 0.064
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.936 0.064
E24.3 Ectopic ACTH syndrome
0.000 0.936 0.064
E24.1 Nelson's syndrome
0.000 0.936 0.064
H54 Blindness and low vision
0.000 0.936 0.064
E25.9 Adrenogenital disorder, unspecified
0.000 0.936 0.064
E25.8 Other adrenogenital disorders
0.000 0.936 0.064
C81.1 Nodular sclerosis
0.001 0.936 0.063
E34 Other endocrine disorders
0.000 0.936 0.064
H54.9 Unspecified visual impairment (binocular)
0.000 0.936 0.064
C92 Myeloid leukaemia
0.000 0.937 0.063
H54.7 Unspecified visual loss
0.000 0.937 0.063
C91.5 Adult T-cell leukaemia
0.000 0.937 0.063
E28 Ovarian dysfunction
0.000 0.938 0.062
E24.9 Cushing's syndrome, unspecified
0.000 0.938 0.062
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.938 0.062
C91.7 Other lymphoid leukaemia
0.000 0.938 0.062
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.938 0.062
C91.3 Prolymphocytic leukaemia
0.000 0.938 0.062
C91.2 Subacute lymphocytic leukaemia
0.000 0.938 0.062
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.938 0.061
E22.8 Other hyperfunction of pituitary gland
0.000 0.938 0.061
E24.2 Drug-induced Cushing's syndrome
0.000 0.939 0.061

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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