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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130531
log Bayes Factor = 72.8729
Chromosome 6   position 31,206,616  (GRCh37) Explore rs3130531 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
E70-E90 Metabolic disorders
0.000 0.002 0.998
E10.9 Without complications
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
E14 Unspecified diabetes mellitus
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.003 0.997
E16 Other disorders of pancreatic internal secretion
0.000 0.005 0.995
E16.2 Hypoglycaemia, unspecified
0.000 0.008 0.992
E10.1 With ketoacidosis
0.000 0.017 0.983
E14.9 Without complications
0.000 0.026 0.974
E78.2 Mixed hyperlipidaemia
0.000 0.028 0.972
E13 Other specified diabetes mellitus
0.000 0.039 0.961
E00-E07 Disorders of thyroid gland
0.000 0.048 0.952
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.050 0.950
E05.9 Thyrotoxicosis, unspecified
0.000 0.057 0.943
E13.9 Without complications
0.000 0.062 0.938
L40.0 Psoriasis vulgaris
0.000 0.069 0.931
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.086 0.914
E14.3 With ophthalmic complications
0.000 0.091 0.909
E11.5 With peripheral circulatory complications
0.000 0.103 0.897
E10.2 With renal complications
0.000 0.106 0.894
E14.8 With unspecified complications
0.000 0.113 0.887
E78.4 Other hyperlipidaemia
0.000 0.119 0.881
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.119 0.881
E14.1 With ketoacidosis
0.000 0.142 0.858
E10.8 With unspecified complications
0.000 0.147 0.853
E11.6 With other specified complications
0.000 0.149 0.851
L40-L45 Papulosquamous disorders
0.000 0.149 0.851
E85 Amyloidosis
0.000 0.156 0.844
E89.3 Postprocedural hypopituitarism
0.000 0.160 0.840
E10.5 With peripheral circulatory complications
0.000 0.161 0.839
E11.0 With coma
0.000 0.174 0.826
L43 Lichen planus
0.000 0.178 0.822
N84.1 Polyp of cervix uteri
0.821 0.179 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.182 0.818
E16.1 Other hypoglycaemia
0.000 0.182 0.818
E79 Disorders of purine and pyrimidine metabolism
0.000 0.195 0.805
E10.0 With coma
0.000 0.196 0.804
L43.9 Lichen planus, unspecified
0.000 0.202 0.798
E11.4 With neurological complications
0.000 0.217 0.783
L40.1 Generalised pustular psoriasis
0.000 0.219 0.781
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.220 0.780
E06 Thyroiditis
0.000 0.222 0.778
E74 Other disorders of carbohydrate metabolism
0.000 0.223 0.777
E10.4 With neurological complications
0.000 0.223 0.777
E11.3 With ophthalmic complications
0.000 0.237 0.763
L40.8 Other psoriasis
0.000 0.244 0.756
E85.4 Organ-limited amyloidosis
0.000 0.245 0.755
E11.1 With ketoacidosis
0.000 0.250 0.750
E40-E46 Malnutrition
0.000 0.254 0.746
E78.6 Lipoprotein deficiency
0.000 0.256 0.744
E89.2 Postprocedural hypoparathyroidism
0.000 0.276 0.724
E70 Disorders of aromatic amino-acid metabolism
0.000 0.281 0.719
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.281 0.719
E14.6 With other specified complications
0.000 0.282 0.718
E10.6 With other specified complications
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
E77 Disorders of glycoprotein metabolism
0.000 0.284 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.284 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.284 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.284 0.716
E14.7 With multiple complications
0.000 0.285 0.715
E14.2 Withrenal complications
0.000 0.285 0.715
E14.0 With coma
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.286 0.714
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.286 0.714
E16.4 Abnormal secretion of gastrin
0.000 0.286 0.714
E16.3 Increased secretion of glucagon
0.000 0.286 0.714
E06.9 Thyroiditis, unspecified
0.000 0.293 0.707
E11.2 With renal complications
0.000 0.294 0.706
L40.3 Pustulosis palmaris et plantaris
0.000 0.303 0.697
E14.5 With peripheral circulatory complications
0.000 0.306 0.694
E13.8 With unspecified complications
0.000 0.311 0.689
E13.7 With multiple complications
0.000 0.311 0.689
E13.6 With other specified complications
0.000 0.311 0.689
E13.5 With peripheral circulatory complications
0.000 0.311 0.689
E13.4 With neurological complications
0.000 0.311 0.689
E13.2 With renal complications
0.000 0.311 0.689
E13.1 With ketoacidosis
0.000 0.311 0.689
E13.0 With coma
0.000 0.311 0.689
E72 Other disorders of amino-acid metabolism
0.000 0.312 0.688
E14.4 With neurological complications
0.000 0.313 0.687
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.317 0.682
E00 Congenital iodine-deficiency syndrome
0.000 0.317 0.682
E05.5 Thyroid crisis or storm
0.000 0.319 0.681
E05.4 Thyrotoxicosis factitia
0.000 0.319 0.681
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.319 0.681
E84 Cystic fibrosis
0.000 0.323 0.676
E11.8 With unspecified complications
0.000 0.331 0.669
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.332 0.667
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.334 0.666
E88 Other metabolic disorders
0.000 0.342 0.658
K90 Intestinal malabsorption
0.000 0.349 0.651
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.349 0.651
E78.8 Other disorders of lipoprotein metabolism
0.000 0.353 0.647
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.368 0.632
E20-E35 Disorders of other endocrine glands
0.000 0.368 0.632
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.368 0.631
E89.5 Postprocedural testicular hypofunction
0.000 0.368 0.631
E89.1 Postprocedural hypoinsulinaemia
0.000 0.368 0.631
E13.3 With ophthalmic complications
0.000 0.370 0.629
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.376 0.624
L43.8 Other lichen planus
0.000 0.378 0.622
L44 Other papulosquamous disorders
0.000 0.390 0.610
L41 Parapsoriasis
0.000 0.390 0.610
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.390 0.610
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.395 0.605
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.395 0.605
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.395 0.605
E85.3 Secondary systemic amyloidosis
0.000 0.396 0.603
L42 Pityriasis rosea
0.000 0.401 0.599
E85.9 Amyloidosis, unspecified
0.000 0.405 0.594
L43.3 Subacute (active) lichen planus
0.000 0.411 0.589
L43.2 Lichenoid drug reaction
0.000 0.411 0.589
L43.1 Bullous lichen planus
0.000 0.411 0.589
L43.0 Hypertrophic lichen planus
0.000 0.411 0.589
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.412 0.588
E05.8 Other thyrotoxicosis
0.000 0.420 0.580
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.423 0.577
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.423 0.577
E79.1 Lesch-Nyhan syndrome
0.000 0.423 0.577
E85.8 Other amyloidosis
0.000 0.435 0.565
E46 Unspecified protein-energy malnutrition
0.000 0.436 0.564
E86 Volume depletion
0.000 0.440 0.560
E06.4 Drug-induced thyroiditis
0.000 0.442 0.558
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.442 0.558
E06.1 Subacute thyroiditis
0.000 0.442 0.558
E06.0 Acute thyroiditis
0.000 0.442 0.558
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.443 0.557
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.443 0.557
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.443 0.557
E74.2 Disorders of galactose metabolism
0.000 0.443 0.557
E74.1 Disorders of fructose metabolism
0.000 0.443 0.557
E89.4 Postprocedural ovarian failure
0.000 0.443 0.557
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.449 0.551
E74.0 Glycogen storage disease
0.000 0.450 0.550
E06.5 Other chronic thyroiditis
0.000 0.451 0.549
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.453 0.547
E24 Cushing's syndrome
0.000 0.453 0.547
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.459 0.541
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.465 0.535
E45 Retarded development following protein-energy malnutrition
0.000 0.465 0.535
E43 Unspecified severe protein-energy malnutrition
0.000 0.465 0.535
E42 Marasmic kwashiorkor
0.000 0.465 0.535
E41 Nutritional marasmus
0.000 0.465 0.535
E40 Kwashiorkor
0.000 0.465 0.535
E88.9 Metabolic disorder, unspecified
0.000 0.471 0.529
E70.3 Albinism
0.000 0.481 0.519
E65-E68 Obesity and other hyperalimentation
0.000 0.481 0.519
K51.9 Ulcerative colitis, unspecified
0.517 0.483 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.484 0.516
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.484 0.516
E70.2 Disorders of tyrosine metabolism
0.000 0.484 0.516
E70.1 Other hyperphenylalaninaemias
0.000 0.484 0.516
E70.0 Classical phenylketonuria
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E71.3 Disorders of fatty-acid metabolism
0.000 0.487 0.513
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.487 0.513
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.487 0.513
E71.0 Maple-syrup-urine disease
0.000 0.487 0.513
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.487 0.513
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.487 0.513
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.487 0.513
E76.2 Other mucopolysaccharidoses
0.000 0.487 0.513
E76.1 Mucopolysaccharidosis, type II
0.000 0.487 0.513
E76.0 Mucopolysaccharidosis, type I
0.000 0.487 0.513
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.487 0.513
E77.8 Other disorders of glycoprotein metabolism
0.000 0.487 0.513
E77.1 Defects in glycoprotein degradation
0.000 0.487 0.513
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.487 0.513
K51 Ulcerative colitis
0.513 0.487 0.000
K90.8 Other intestinal malabsorption
0.000 0.499 0.501
E26 Hyperaldosteronism
0.000 0.501 0.499
E73 Lactose intolerance
0.001 0.501 0.498
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.507 0.493
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.507 0.493
E72.5 Disorders of glycine metabolism
0.000 0.507 0.493
E72.4 Disorders of ornithine metabolism
0.000 0.507 0.493
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.507 0.493
E72.2 Disorders of urea cycle metabolism
0.000 0.507 0.493
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.507 0.493
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.510 0.489
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.510 0.489
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.510 0.489
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.510 0.489
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.510 0.489
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.510 0.489
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.510 0.489
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.510 0.489
E88.2 Lipomatosis, not elsewhere classified
0.000 0.511 0.489
K51.4 Pseudopolyposis of colon
0.488 0.512 0.000
K51.8 Other ulcerative colitis
0.487 0.513 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.513 0.487
E84.8 Cystic fibrosis with other manifestations
0.000 0.515 0.485
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.515 0.485
E84.9 Cystic fibrosis, unspecified
0.000 0.519 0.481
E25 Adrenogenital disorders
0.000 0.521 0.479
E88.8 Other specified metabolic disorders
0.000 0.527 0.473
E21.0 Primary hyperparathyroidism
0.000 0.529 0.471
E50-E64 Other nutritional deficiencies
0.000 0.532 0.467
K90.3 Pancreatic steatorrhoea
0.000 0.533 0.467
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.533 0.467
K90.1 Tropical sprue
0.000 0.533 0.467
E24.0 Pituitary-dependent Cushing's disease
0.000 0.534 0.466
K51.5 Mucosal proctocolitis
0.465 0.535 0.000
E72.0 Disorders of amino-acid transport
0.000 0.535 0.465
E34 Other endocrine disorders
0.000 0.535 0.465
E75.6 Lipid storage disorder, unspecified
0.000 0.547 0.453
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.547 0.453
E75.3 Sphingolipidosis, unspecified
0.000 0.547 0.453
E75.1 Other gangliosidosis
0.000 0.547 0.453
E75.0 GM2 gangliosidosis
0.000 0.547 0.453
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.547 0.453
E32 Diseases of thymus
0.000 0.547 0.453
E30 Disorders of puberty, not elsewhere classified
0.000 0.547 0.453
E88.3 Tumour lysis syndrome
0.000 0.547 0.453
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.548 0.452
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.550 0.450
L41.9 Parapsoriasis, unspecified
0.000 0.563 0.437
L41.8 Other parapsoriasis
0.000 0.563 0.437
L41.5 Retiform parapsoriasis
0.000 0.563 0.437
L41.4 Large plaque parapsoriasis
0.000 0.563 0.437
L41.3 Small plaque parapsoriasis
0.000 0.563 0.437
L41.2 Lymphomatoid papulosis
0.000 0.563 0.437
L41.1 Pityriasis lichenoides chronica
0.000 0.563 0.437
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.563 0.437
L44.9 Papulosquamous disorder, unspecified
0.000 0.563 0.437
L44.8 Other specified papulosquamous disorders
0.000 0.563 0.437
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.563 0.437
L44.3 Lichen ruber moniliformis
0.000 0.563 0.437
L44.2 Lichen striatus
0.000 0.563 0.437
L44.1 Lichen nitidus
0.000 0.563 0.437
L44.0 Pityriasis rubra pilaris
0.000 0.563 0.437
E22 Hyperfunction of pituitary gland
0.000 0.565 0.435
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.565 0.435
E78.1 Pure hyperglyceridaemia
0.001 0.566 0.434
E24.2 Drug-induced Cushing's syndrome
0.000 0.577 0.423
E31 Polyglandular dysfunction
0.000 0.578 0.421
E24.9 Cushing's syndrome, unspecified
0.000 0.579 0.421
E75.5 Other lipid storage disorders
0.000 0.583 0.416
E75.2 Other sphingolipidosis
0.000 0.586 0.414
E06.3 Autoimmune thyroiditis
0.000 0.594 0.406
K51.3 Ulcerative (chronic) rectosigmoiditis
0.404 0.596 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.603 0.397
E07 Other disorders of thyroid
0.001 0.603 0.396
K51.1 Ulcerative (chronic) ileocolitis
0.396 0.604 0.000
E26.0 Primary hyperaldosteronism
0.000 0.605 0.395
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.608 0.392
E24.3 Ectopic ACTH syndrome
0.000 0.608 0.392
E24.1 Nelson's syndrome
0.000 0.608 0.392
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.609 0.391
E21.4 Other specified disorders of parathyroid gland
0.000 0.612 0.388
E21.2 Other hyperparathyroidism
0.000 0.615 0.385
E44.1 Mild protein-energy malnutrition
0.000 0.616 0.384
E44.0 Moderate protein-energy malnutrition
0.000 0.616 0.384
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.617 0.383
E27 Other disorders of adrenal gland
0.000 0.617 0.383
E34.9 Endocrine disorder, unspecified
0.000 0.619 0.381
E29 Testicular dysfunction
0.000 0.620 0.379
E67 Other hyperalimentation
0.000 0.628 0.372
E68 Sequelae of hyperalimentation
0.000 0.628 0.372
E51 Thiamine deficiency
0.000 0.628 0.372
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.630 0.370
E24.8 Other Cushing's syndrome
0.000 0.631 0.369
E20 Hypoparathyroidism
0.000 0.631 0.369
E26.9 Hyperaldosteronism, unspecified
0.000 0.631 0.368
K51.0 Ulcerative (chronic) enterocolitis
0.366 0.634 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.636 0.363
E26.8 Other hyperaldosteronism
0.000 0.642 0.358
E26.1 Secondary hyperaldosteronism
0.000 0.642 0.358
E73.8 Other lactose intolerance
0.001 0.642 0.357
E73.1 Secondary lactase deficiency
0.001 0.642 0.357
E73.0 Congenital lactase deficiency
0.001 0.642 0.357
E65 Localised adiposity
0.000 0.650 0.350
E23.6 Other disorders of pituitary gland
0.000 0.654 0.346
E22.1 Hyperprolactinaemia
0.000 0.654 0.346
E25.9 Adrenogenital disorder, unspecified
0.000 0.656 0.344
E25.8 Other adrenogenital disorders
0.000 0.656 0.344
E56 Other vitamin deficiencies
0.000 0.658 0.341
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.665 0.335
E63 Other nutritional deficiencies
0.000 0.665 0.335
E50 Vitamin A deficiency
0.000 0.665 0.335
E60 Dietary zinc deficiency
0.000 0.665 0.335
E59 Dietary selenium deficiency
0.000 0.665 0.335
E52 Niacin deficiency [pellagra]
0.000 0.665 0.335
E34.5 Androgen resistance syndrome
0.000 0.667 0.333
E34.4 Constitutional tall stature
0.000 0.667 0.333
E34.3 Short stature, not elsewhere classified
0.000 0.667 0.333
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.667 0.333
E34.1 Other hypersecretion of intestinal hormones
0.000 0.667 0.333
E54 Ascorbic acid deficiency
0.000 0.669 0.331
E30.9 Disorder of puberty, unspecified
0.000 0.675 0.325
E30.8 Other disorders of puberty
0.000 0.675 0.325
E30.1 Precocious puberty
0.000 0.675 0.325
E30.0 Delayed puberty
0.000 0.675 0.325
E32.9 Disease of thymus, unspecified
0.000 0.675 0.325
E32.8 Other diseases of thymus
0.000 0.675 0.325
E32.1 Abscess of thymus
0.000 0.675 0.325
E32.0 Persistent hyperplasia of thymus
0.000 0.675 0.325
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.675 0.325
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.675 0.325
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.675 0.325
E55 Vitamin D deficiency
0.000 0.676 0.323
E58 Dietary calcium deficiency
0.000 0.678 0.322
E34.8 Other specified endocrine disorders
0.000 0.679 0.321
E27.1 Primary adrenocortical insufficiency
0.000 0.681 0.319
K51.2 Ulcerative (chronic) proctitis
0.319 0.681 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.682 0.318
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.684 0.316
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.688 0.312
E22.8 Other hyperfunction of pituitary gland
0.000 0.688 0.312
E51.2 Wernicke's encephalopathy
0.000 0.696 0.304
E31.9 Polyglandular dysfunction, unspecified
0.000 0.698 0.302
E31.8 Other polyglandular dysfunction
0.000 0.698 0.302
E31.1 Polyglandular hyperfunction
0.000 0.698 0.302
E34.0 Carcinoid syndrome
0.000 0.707 0.293
N84 Polyp of female genital tract
0.292 0.708 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.710 0.290
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.715 0.285
E23.1 Drug-induced hypopituitarism
0.000 0.715 0.285
E07.1 Dyshormogenetic goitre
0.001 0.715 0.284
E07.0 Hypersecretion of calcitonin
0.001 0.715 0.284
E23.7 Disorder of pituitary gland, unspecified
0.000 0.717 0.283
E80.2 Other porphyria
0.001 0.722 0.277
E27.9 Disorder of adrenal gland, unspecified
0.000 0.724 0.276
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.725 0.274
E80.5 Crigler-Najjar syndrome
0.001 0.725 0.274
E80.3 Defects of catalase and peroxydase
0.001 0.725 0.274
E80.0 Hereditary erythropoietic porphyria
0.001 0.725 0.274
E27.5 Adrenomedullary hyperfunction
0.000 0.725 0.275
E27.0 Other adrenocortical overactivity
0.000 0.725 0.275
E29.8 Other testicular dysfunction
0.000 0.728 0.272
E29.0 Testicular hyperfunction
0.000 0.728 0.272
E31.0 Autoimmune polyglandular failure
0.000 0.729 0.270
E07.8 Other specified disorders of thyroid
0.001 0.729 0.270
E80.1 Porphyria cutanea tarda
0.001 0.731 0.268
E03 Other hypothyroidism
0.000 0.732 0.268
E67.8 Other specified hyperalimentation
0.000 0.733 0.267
E67.3 Hypervitaminosis D
0.000 0.733 0.267
E67.2 Megavitamin-B6 syndrome
0.000 0.733 0.267
E67.1 Hypercarotenaemia
0.000 0.733 0.267
E67.0 Hypervitaminosis A
0.000 0.733 0.267
E51.9 Thiamine deficiency, unspecified
0.000 0.733 0.267
E51.8 Other manifestations of thiamine deficiency
0.000 0.733 0.267
E51.1 Beriberi
0.000 0.733 0.267
E61 Deficiency of other nutrient elements
0.000 0.734 0.266
E20.8 Other hypoparathyroidism
0.000 0.735 0.265
E20.1 Pseudohypoparathyroidism
0.000 0.735 0.265
E20.0 Idiopathic hypoparathyroidism
0.000 0.735 0.265
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.736 0.263
E29.9 Testicular dysfunction, unspecified
0.000 0.741 0.259
E28 Ovarian dysfunction
0.000 0.741 0.258
N84.3 Polyp of vulva
0.258 0.742 0.000
E56.1 Deficiency of vitamin K
0.000 0.749 0.251
E56.9 Vitamin deficiency, unspecified
0.000 0.755 0.245
E56.8 Deficiency of other vitamins
0.000 0.755 0.245
E56.0 Deficiency of vitamin E
0.000 0.755 0.245
E80.6 Other disorders of bilirubin metabolism
0.001 0.756 0.243
E50.9 Vitamin A deficiency, unspecified
0.000 0.759 0.240
E50.8 Other manifestations of vitamin A deficiency
0.000 0.759 0.240
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.759 0.240
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.759 0.240
E50.5 Vitamin A deficiency with night blindness
0.000 0.759 0.240
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.759 0.240
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.759 0.240
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.759 0.240
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.759 0.240
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.759 0.240
E63.9 Nutritional deficiency, unspecified
0.000 0.759 0.240
E63.8 Other specified nutritional deficiencies
0.000 0.759 0.240
E63.1 Imbalance of constituents of food intake
0.000 0.759 0.240
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.759 0.240
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.759 0.240
E64.8 Sequelae of other nutritional deficiencies
0.000 0.759 0.240
E64.3 Sequelae of rickets
0.000 0.759 0.240
E64.2 Sequelae of vitamin C deficiency
0.000 0.759 0.240
E64.1 Sequelae of vitamin A deficiency
0.000 0.759 0.240
E64.0 Sequelae of protein-energy malnutrition
0.000 0.759 0.240
E55.0 Rickets, active
0.000 0.768 0.232
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.771 0.229
N84.9 Polyp of female genital tract, unspecified
0.225 0.775 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.780 0.220
E66 Obesity
0.000 0.781 0.219
E29.1 Testicular hypofunction
0.000 0.782 0.218
N84.8 Polyp of other parts of female genital tract
0.204 0.795 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.795 0.204
E23.2 Diabetes insipidus
0.000 0.798 0.202
E03.5 Myxoedema coma
0.000 0.808 0.192
E03.4 Atrophy of thyroid (acquired)
0.000 0.808 0.192
E03.3 Postinfectious hypothyroidism
0.000 0.808 0.192
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.808 0.192
E61.9 Deficiency of nutrient element, unspecified
0.000 0.809 0.191
E61.8 Deficiency of other specified nutrient elements
0.000 0.809 0.191
E61.7 Deficiency of multiple nutrient elements
0.000 0.809 0.191
E61.6 Vanadium deficiency
0.000 0.809 0.191
E61.5 Molybdenum deficiency
0.000 0.809 0.191
E61.4 Chromium deficiency
0.000 0.809 0.191
E61.3 Manganese deficiency
0.000 0.809 0.191
E61.0 Copper deficiency
0.000 0.809 0.191
E23.0 Hypopituitarism
0.000 0.812 0.188
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.813 0.187
E28.9 Ovarian dysfunction, unspecified
0.000 0.814 0.185
E28.8 Other ovarian dysfunction
0.000 0.814 0.185
E28.1 Androgen excess
0.000 0.814 0.185
E28.0 Oestrogen excess
0.000 0.814 0.185
E61.2 Magnesium deficiency
0.000 0.819 0.181
E20.9 Hypoparathyroidism, unspecified
0.001 0.819 0.180
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.824 0.175
E66.0 Obesity due to excess calories
0.000 0.827 0.173
E53 Deficiency of other B group vitamins
0.000 0.828 0.172
N84.0 Polyp of corpus uteri
0.169 0.831 0.000
E27.2 Addisonian crisis
0.001 0.836 0.163
E27.8 Other specified disorders of adrenal gland
0.000 0.836 0.163
E66.1 Drug-induced obesity
0.000 0.843 0.157
E89.0 Postprocedural hypothyroidism
0.000 0.849 0.151
E73.9 Lactose intolerance, unspecified
0.002 0.859 0.139
E61.1 Iron deficiency
0.000 0.862 0.138
E03.8 Other specified hypothyroidism
0.000 0.867 0.133
E28.2 Polycystic ovarian syndrome
0.000 0.869 0.131
E53.1 Pyridoxine deficiency
0.000 0.876 0.124
E53.0 Riboflavin deficiency
0.000 0.876 0.124
E83 Disorders of mineral metabolism
0.021 0.876 0.102
E28.3 Primary ovarian failure
0.001 0.894 0.105
E53.9 Vitamin B deficiency, unspecified
0.000 0.897 0.102
E83.1 Disorders of iron metabolism
0.094 0.905 0.001
E83.8 Other disorders of mineral metabolism
0.016 0.911 0.073
E83.2 Disorders of zinc metabolism
0.016 0.911 0.073
E83.0 Disorders of copper metabolism
0.016 0.911 0.073
N84.2 Polyp of vagina
0.087 0.913 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.016 0.915 0.069
K31.8 Other specified diseases of stomach and duodenum
0.000 0.916 0.084
E04 Other non-toxic goitre
0.000 0.928 0.072
E83.4 Disorders of magnesium metabolism
0.005 0.928 0.067
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.000 0.939 0.061
E66.8 Other obesity
0.000 0.942 0.058
E04.8 Other specified non-toxic goitre
0.000 0.948 0.052
E80.4 Gilbert's syndrome
0.001 0.950 0.049
E83.3 Disorders of phosphorus metabolism
0.017 0.951 0.032
K90-K93 Other diseases of the digestive system
0.000 0.953 0.047
E07.9 Disorder of thyroid, unspecified
0.002 0.957 0.041
E83.5 Disorders of calcium metabolism
0.002 0.957 0.041
E04.0 Non-toxic diffuse goitre
0.000 0.959 0.040
K50-K52 Noninfective enteritis and colitis
0.040 0.960 0.000
S64.4 Injury of digital nerve of other finger
0.034 0.966 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.966 0.034
Z86.1 Personal history of infectious and parasitic diseases
0.000 0.970 0.030
E53.8 Deficiency of other specified B group vitamins
0.000 0.975 0.025
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.975 0.024
K93.1 Megacolon in Chagas' disease
0.000 0.975 0.024
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.975 0.024
E04.1 Non-toxic single thyroid nodule
0.000 0.976 0.023
E04.9 Non-toxic goitre, unspecified
0.000 0.978 0.022
J45.9 Asthma, unspecified
0.000 0.983 0.017
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.987 0.013
K05.3 Chronic periodontitis
0.000 0.988 0.012
K50 Crohn's disease [regional enteritis]
0.012 0.988 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.989 0.011
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.989 0.011
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.000 0.990 0.010
E66.9 Obesity, unspecified
0.000 0.990 0.010
K50.9 Crohn's disease, unspecified
0.010 0.990 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.990 0.010
E87.7 Fluid overload
0.000 0.990 0.010
K91.1 Postgastric surgery syndromes
0.000 0.991 0.009
E87.4 Mixed disorder of acid-base balance
0.000 0.992 0.008
S64 Injury of nerves at wrist and hand level
0.008 0.992 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.000 0.992 0.008
K91.5 Postcholecystectomy syndrome
0.000 0.992 0.008
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.992 0.008
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.992 0.008
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.992 0.008
S64.2 Injury of radial nerve at wrist and hand level
0.008 0.992 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.000 0.993 0.007
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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