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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130688
log Bayes Factor = 74.9524
Chromosome 6   position 31,210,216  (GRCh37) Explore rs3130688 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.004 0.996
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.006 0.994
E11 Non-insulin-dependent diabetes mellitus
0.000 0.006 0.994
E11.9 Without complications
0.000 0.008 0.992
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.015 0.985
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.017 0.983
E14 Unspecified diabetes mellitus
0.000 0.020 0.980
M45 Ankylosing spondylitis
0.969 0.031 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.033 0.967
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.944 0.056 0.000
E11.1 With ketoacidosis
0.000 0.061 0.939
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.073 0.927
E11.0 With coma
0.000 0.090 0.910
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.096 0.904
L40 Psoriasis
0.000 0.098 0.902
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.100 0.900
E14.9 Without complications
0.000 0.104 0.896
E05.9 Thyrotoxicosis, unspecified
0.000 0.112 0.888
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.112 0.888
K90 Intestinal malabsorption
0.000 0.112 0.888
E00-E07 Disorders of thyroid gland
0.000 0.115 0.885
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.116 0.884
E10.5 With peripheral circulatory complications
0.000 0.116 0.884
E16 Other disorders of pancreatic internal secretion
0.000 0.119 0.881
E20-E35 Disorders of other endocrine glands
0.000 0.119 0.881
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.125 0.875
E16.2 Hypoglycaemia, unspecified
0.000 0.136 0.864
E10.0 With coma
0.000 0.143 0.857
L40.0 Psoriasis vulgaris
0.000 0.149 0.851
E10.8 With unspecified complications
0.000 0.159 0.841
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.167 0.833
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.167 0.833
K90.9 Intestinal malabsorption, unspecified
0.000 0.177 0.823
E14.3 With ophthalmic complications
0.000 0.186 0.814
M45.X6 Ankylosing spondylitis (Lumbar region)
0.811 0.189 0.000
E14.1 With ketoacidosis
0.000 0.190 0.810
M45.X2 Ankylosing spondylitis (Cervical region)
0.807 0.193 0.000
E14.6 With other specified complications
0.000 0.201 0.799
E22 Hyperfunction of pituitary gland
0.000 0.204 0.796
E14.2 Withrenal complications
0.000 0.204 0.796
E11.5 With peripheral circulatory complications
0.000 0.205 0.795
L40.5 Arthropathic psoriasis
0.000 0.214 0.786
E13 Other specified diabetes mellitus
0.000 0.214 0.786
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.217 0.783
E14.8 With unspecified complications
0.000 0.219 0.781
E10.2 With renal complications
0.000 0.227 0.773
E10.6 With other specified complications
0.000 0.239 0.761
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.254 0.746
E10.4 With neurological complications
0.000 0.255 0.745
M06 Other rheumatoid arthritis
0.000 0.261 0.738
E16.1 Other hypoglycaemia
0.000 0.265 0.735
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.266 0.734
E21.3 Hyperparathyroidism, unspecified
0.000 0.282 0.718
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.287 0.713
M06.3 Rheumatoid nodule
0.000 0.288 0.712
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.296 0.704
E14.7 With multiple complications
0.000 0.297 0.703
E14.0 With coma
0.000 0.297 0.703
E23 Hypofunction and other disorders of pituitary gland
0.000 0.301 0.699
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.302 0.697
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.694 0.305 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.694 0.305 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.694 0.305 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.694 0.305 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.694 0.305 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.694 0.305 0.000
E21.0 Primary hyperparathyroidism
0.000 0.314 0.686
E25 Adrenogenital disorders
0.000 0.315 0.685
E14.5 With peripheral circulatory complications
0.000 0.324 0.676
J45.9 Asthma, unspecified
0.000 0.329 0.671
E40-E46 Malnutrition
0.000 0.330 0.669
L40.8 Other psoriasis
0.000 0.333 0.667
L40.4 Guttate psoriasis
0.000 0.336 0.664
E28 Ovarian dysfunction
0.000 0.337 0.663
E13.9 Without complications
0.000 0.338 0.662
E10.7 With multiple complications
0.000 0.345 0.655
K90.8 Other intestinal malabsorption
0.000 0.349 0.651
L40.1 Generalised pustular psoriasis
0.000 0.352 0.648
L40.2 Acrodermatitis continua
0.000 0.353 0.647
E15 Nondiabetic hypoglycaemic coma
0.000 0.354 0.646
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.354 0.646
E05.5 Thyroid crisis or storm
0.000 0.363 0.637
E05.4 Thyrotoxicosis factitia
0.000 0.363 0.637
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.363 0.637
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.363 0.637
K90.3 Pancreatic steatorrhoea
0.000 0.363 0.637
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.363 0.637
K90.1 Tropical sprue
0.000 0.363 0.637
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.366 0.634
E00 Congenital iodine-deficiency syndrome
0.000 0.366 0.634
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.368 0.632
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.368 0.632
E16.4 Abnormal secretion of gastrin
0.000 0.368 0.632
E16.3 Increased secretion of glucagon
0.000 0.368 0.632
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.369 0.631
E32 Diseases of thymus
0.000 0.369 0.631
E30 Disorders of puberty, not elsewhere classified
0.000 0.369 0.631
E31 Polyglandular dysfunction
0.000 0.382 0.618
E20 Hypoparathyroidism
0.000 0.384 0.616
E05.8 Other thyrotoxicosis
0.000 0.387 0.613
E29 Testicular dysfunction
0.000 0.393 0.607
E14.4 With neurological complications
0.000 0.398 0.602
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.400 0.600
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.401 0.599
E22.1 Hyperprolactinaemia
0.000 0.401 0.599
E21.4 Other specified disorders of parathyroid gland
0.000 0.402 0.597
E27 Other disorders of adrenal gland
0.000 0.406 0.594
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.411 0.589
E34 Other endocrine disorders
0.000 0.422 0.578
M06.34 Rheumatoid nodule (Hand)
0.000 0.422 0.578
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.429 0.571
E22.8 Other hyperfunction of pituitary gland
0.000 0.429 0.571
L40.3 Pustulosis palmaris et plantaris
0.000 0.431 0.568
M06.4 Inflammatory polyarthropathy
0.000 0.432 0.568
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.434 0.565
E21.2 Other hyperparathyroidism
0.000 0.435 0.565
E24 Cushing's syndrome
0.000 0.435 0.564
E13.8 With unspecified complications
0.000 0.436 0.564
E13.7 With multiple complications
0.000 0.436 0.564
E13.6 With other specified complications
0.000 0.436 0.564
E13.5 With peripheral circulatory complications
0.000 0.436 0.564
E13.4 With neurological complications
0.000 0.436 0.564
E13.2 With renal complications
0.000 0.436 0.564
E13.1 With ketoacidosis
0.000 0.436 0.564
E13.0 With coma
0.000 0.436 0.564
E28.2 Polycystic ovarian syndrome
0.000 0.437 0.563
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.445 0.555
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.447 0.552
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.456 0.544
E23.7 Disorder of pituitary gland, unspecified
0.000 0.456 0.544
K51.9 Ulcerative colitis, unspecified
0.540 0.460 0.000
E23.6 Other disorders of pituitary gland
0.000 0.460 0.540
M06.2 Rheumatoid bursitis
0.000 0.470 0.529
M06.1 Adult-onset Still's disease
0.000 0.470 0.529
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.478 0.522
E27.9 Disorder of adrenal gland, unspecified
0.000 0.480 0.520
E23.2 Diabetes insipidus
0.000 0.482 0.518
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E13.3 With ophthalmic complications
0.000 0.489 0.510
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.490 0.510
M06.38 Rheumatoid nodule (Other)
0.000 0.490 0.510
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.490 0.510
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.490 0.510
M06.33 Rheumatoid nodule (Forearm)
0.000 0.490 0.510
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.490 0.510
E11.6 With other specified complications
0.000 0.498 0.501
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.498 0.501
E23.1 Drug-induced hypopituitarism
0.000 0.498 0.501
K51 Ulcerative colitis
0.501 0.499 0.000
K51.4 Pseudopolyposis of colon
0.497 0.503 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.509 0.491
E25.9 Adrenogenital disorder, unspecified
0.000 0.509 0.491
E25.8 Other adrenogenital disorders
0.000 0.509 0.491
E22.0 Acromegaly and pituitary gigantism
0.000 0.512 0.488
M06.8 Other specified rheumatoid arthritis
0.000 0.514 0.485
E46 Unspecified protein-energy malnutrition
0.000 0.515 0.485
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.520 0.480
E45 Retarded development following protein-energy malnutrition
0.000 0.520 0.480
E43 Unspecified severe protein-energy malnutrition
0.000 0.520 0.480
E42 Marasmic kwashiorkor
0.000 0.520 0.480
E41 Nutritional marasmus
0.000 0.520 0.480
E40 Kwashiorkor
0.000 0.520 0.480
E28.9 Ovarian dysfunction, unspecified
0.000 0.524 0.475
E28.8 Other ovarian dysfunction
0.000 0.524 0.475
E28.1 Androgen excess
0.000 0.524 0.475
E28.0 Oestrogen excess
0.000 0.524 0.475
E23.0 Hypopituitarism
0.000 0.525 0.475
E34.9 Endocrine disorder, unspecified
0.000 0.526 0.474
E11.8 With unspecified complications
0.000 0.530 0.470
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.537 0.463
E11.4 With neurological complications
0.000 0.542 0.458
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.545 0.455
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.545 0.455
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.545 0.455
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.545 0.455
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.545 0.455
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.545 0.455
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.545 0.455
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.545 0.455
E30.9 Disorder of puberty, unspecified
0.000 0.547 0.453
E30.8 Other disorders of puberty
0.000 0.547 0.453
E30.1 Precocious puberty
0.000 0.547 0.453
E30.0 Delayed puberty
0.000 0.547 0.453
E32.9 Disease of thymus, unspecified
0.000 0.547 0.453
E32.8 Other diseases of thymus
0.000 0.547 0.453
E32.1 Abscess of thymus
0.000 0.547 0.453
E32.0 Persistent hyperplasia of thymus
0.000 0.547 0.453
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.547 0.453
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.547 0.453
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.547 0.453
E31.9 Polyglandular dysfunction, unspecified
0.000 0.557 0.443
E31.8 Other polyglandular dysfunction
0.000 0.557 0.443
E31.1 Polyglandular hyperfunction
0.000 0.557 0.443
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.557 0.443
E20.8 Other hypoparathyroidism
0.000 0.558 0.442
E20.1 Pseudohypoparathyroidism
0.000 0.558 0.442
E20.0 Idiopathic hypoparathyroidism
0.000 0.558 0.442
E24.0 Pituitary-dependent Cushing's disease
0.000 0.561 0.439
E29.9 Testicular dysfunction, unspecified
0.000 0.565 0.435
E29.8 Other testicular dysfunction
0.000 0.565 0.435
E29.0 Testicular hyperfunction
0.000 0.565 0.435
E03 Other hypothyroidism
0.000 0.565 0.435
E31.0 Autoimmune polyglandular failure
0.000 0.570 0.430
K51.3 Ulcerative (chronic) rectosigmoiditis
0.429 0.571 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.573 0.427
E27.5 Adrenomedullary hyperfunction
0.000 0.574 0.426
E27.0 Other adrenocortical overactivity
0.000 0.574 0.426
E34.5 Androgen resistance syndrome
0.000 0.585 0.414
E34.4 Constitutional tall stature
0.000 0.585 0.414
E34.3 Short stature, not elsewhere classified
0.000 0.585 0.414
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.585 0.414
E34.1 Other hypersecretion of intestinal hormones
0.000 0.585 0.414
E29.1 Testicular hypofunction
0.000 0.590 0.410
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.593 0.407
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.593 0.407
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.593 0.407
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.593 0.407
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.593 0.407
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.593 0.407
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.593 0.407
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.593 0.407
E06 Thyroiditis
0.000 0.593 0.406
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.595 0.405
E24.3 Ectopic ACTH syndrome
0.000 0.595 0.405
E24.1 Nelson's syndrome
0.000 0.595 0.405
E26 Hyperaldosteronism
0.001 0.597 0.402
K51.8 Other ulcerative colitis
0.401 0.599 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.600 0.400
K51.5 Mucosal proctocolitis
0.386 0.614 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.619 0.381
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.620 0.380
M06.18 Adult-onset Still's disease (Other)
0.000 0.620 0.380
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.620 0.380
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.620 0.380
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.620 0.380
M06.14 Adult-onset Still's disease (Hand)
0.000 0.620 0.380
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.620 0.380
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.620 0.380
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.620 0.380
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.620 0.380
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.620 0.380
M06.28 Rheumatoid bursitis (Other)
0.000 0.620 0.380
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.620 0.380
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.620 0.380
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.620 0.380
M06.24 Rheumatoid bursitis (Hand)
0.000 0.620 0.380
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.620 0.380
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.620 0.380
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.620 0.380
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.620 0.380
E28.3 Primary ovarian failure
0.000 0.628 0.372
E27.2 Addisonian crisis
0.000 0.637 0.362
E34.0 Carcinoid syndrome
0.000 0.640 0.359
E24.9 Cushing's syndrome, unspecified
0.000 0.641 0.359
E07 Other disorders of thyroid
0.000 0.649 0.350
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.652 0.348
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.652 0.348
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.652 0.348
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.652 0.348
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.652 0.348
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.652 0.348
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.652 0.348
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.652 0.348
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.652 0.348
E24.8 Other Cushing's syndrome
0.000 0.654 0.346
E44.1 Mild protein-energy malnutrition
0.000 0.656 0.344
E44.0 Moderate protein-energy malnutrition
0.000 0.656 0.344
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.664 0.336
E03.1 Congenital hypothyroidism without goitre
0.000 0.670 0.330
E11.2 With renal complications
0.000 0.671 0.329
E34.8 Other specified endocrine disorders
0.000 0.677 0.323
E03.5 Myxoedema coma
0.000 0.688 0.312
E03.4 Atrophy of thyroid (acquired)
0.000 0.688 0.312
E03.3 Postinfectious hypothyroidism
0.000 0.688 0.312
E03.8 Other specified hypothyroidism
0.000 0.689 0.311
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.001 0.695 0.304
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.697 0.303
E06.5 Other chronic thyroiditis
0.000 0.700 0.300
E06.1 Subacute thyroiditis
0.000 0.705 0.294
E06.4 Drug-induced thyroiditis
0.000 0.708 0.291
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.708 0.291
E06.0 Acute thyroiditis
0.000 0.708 0.291
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.710 0.290
G35 Multiple sclerosis
0.289 0.711 0.000
E26.8 Other hyperaldosteronism
0.001 0.711 0.288
E26.1 Secondary hyperaldosteronism
0.001 0.711 0.288
K51.1 Ulcerative (chronic) ileocolitis
0.288 0.712 0.000
E65-E68 Obesity and other hyperalimentation
0.001 0.729 0.270
M05-M14 Inflammatory polyarthropathies
0.001 0.731 0.268
K51.2 Ulcerative (chronic) proctitis
0.261 0.739 0.000
M05 Seropositive rheumatoid arthritis
0.001 0.739 0.261
K51.0 Ulcerative (chronic) enterocolitis
0.259 0.741 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.742 0.258
E50-E64 Other nutritional deficiencies
0.000 0.743 0.257
E27.8 Other specified disorders of adrenal gland
0.000 0.744 0.256
E07.1 Dyshormogenetic goitre
0.000 0.748 0.251
E07.0 Hypersecretion of calcitonin
0.000 0.748 0.251
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.752 0.248
J45 Asthma
0.000 0.756 0.244
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.765 0.235
E06.9 Thyroiditis, unspecified
0.000 0.767 0.233
M45-M49 Spondylopathies
0.226 0.774 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.775 0.224
E11.3 With ophthalmic complications
0.000 0.775 0.225
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.785 0.215
M07 Psoriatic and enteropathic arthropathies
0.001 0.786 0.214
L40-L45 Papulosquamous disorders
0.000 0.788 0.212
M12 Other specific arthropathies
0.001 0.794 0.205
M48 Other spondylopathies
0.205 0.795 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.795 0.204
M48.5 Collapsed vertebra, not elsewhere classified
0.203 0.797 0.000
E07.8 Other specified disorders of thyroid
0.000 0.798 0.202
E83.1 Disorders of iron metabolism
0.201 0.799 0.000
J45.1 Nonallergic asthma
0.000 0.800 0.200
E67 Other hyperalimentation
0.001 0.805 0.194
E68 Sequelae of hyperalimentation
0.001 0.805 0.194
M09 Juvenile arthritis in diseases classified elsewhere
0.001 0.807 0.192
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.192 0.808 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.812 0.187
M05.1 Rheumatoid lung disease
0.001 0.812 0.187
M05.0 Felty's syndrome
0.001 0.812 0.187
M08 Juvenile arthritis
0.001 0.813 0.186
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.815 0.185
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.815 0.185
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.815 0.185
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.815 0.185
J45.8 Mixed asthma
0.000 0.815 0.185
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.816 0.184
E63 Other nutritional deficiencies
0.000 0.816 0.184
E50 Vitamin A deficiency
0.000 0.816 0.184
E60 Dietary zinc deficiency
0.000 0.816 0.184
E59 Dietary selenium deficiency
0.000 0.816 0.184
E54 Ascorbic acid deficiency
0.000 0.816 0.184
E52 Niacin deficiency [pellagra]
0.000 0.816 0.184
E26.0 Primary hyperaldosteronism
0.001 0.816 0.183
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.183 0.817 0.000
M07.3 Other psoriatic arthropathies
0.000 0.819 0.181
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.821 0.178
E51 Thiamine deficiency
0.000 0.823 0.177
E56 Other vitamin deficiencies
0.000 0.824 0.176
E55 Vitamin D deficiency
0.000 0.824 0.176
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.829 0.171
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.832 0.168
G35-G37 Demyelinating diseases of the central nervous system
0.168 0.832 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.836 0.164
M12.2 Villonodular synovitis (pigmented)
0.000 0.837 0.163
E58 Dietary calcium deficiency
0.000 0.840 0.160
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.159 0.841 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.842 0.158
E06.3 Autoimmune thyroiditis
0.000 0.844 0.156
M11 Other crystal arthropathies
0.001 0.845 0.154
M14 Arthropathies in other diseases classified elsewhere
0.001 0.845 0.154
M07.5 Arthropathy in ulcerative colitis
0.001 0.846 0.153
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.846 0.153
M07.2 Psoriatic spondylitis
0.001 0.846 0.153
M07.1 Arthritis mutilans
0.001 0.846 0.153
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.846 0.153
L44 Other papulosquamous disorders
0.000 0.848 0.152
L41 Parapsoriasis
0.000 0.848 0.152
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.848 0.152
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.152 0.848 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.001 0.852 0.147
M12.5 Traumatic arthropathy
0.001 0.852 0.147
M12.4 Intermittent hydrarthrosis
0.001 0.852 0.147
M12.1 Kaschin-Beck disease
0.001 0.852 0.147
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.001 0.852 0.147
M48.4 Fatigue fracture of vertebra
0.147 0.853 0.000
M48.3 Traumatic spondylopathy
0.147 0.853 0.000
M48.2 Kissing spine
0.147 0.853 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.147 0.853 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.853 0.147
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.853 0.147
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.853 0.147
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.853 0.147
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.853 0.147
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.853 0.147
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.853 0.147
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.853 0.147
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.853 0.147
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.146 0.854 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.146 0.854 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.146 0.854 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.146 0.854 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.146 0.854 0.000
M12.3 Palindromic rheumatism
0.001 0.855 0.144
M05.2 Rheumatoid vasculitis
0.001 0.855 0.144
M48.9 Spondylopathy, unspecified
0.143 0.857 0.000
M07.6 Other enteropathic arthropathies
0.001 0.858 0.141
J33.0 Polyp of nasal cavity
0.000 0.858 0.142
L42 Pityriasis rosea
0.000 0.859 0.141
E67.8 Other specified hyperalimentation
0.001 0.860 0.139
E67.3 Hypervitaminosis D
0.001 0.860 0.139
E67.2 Megavitamin-B6 syndrome
0.001 0.860 0.139
E67.1 Hypercarotenaemia
0.001 0.860 0.139
E67.0 Hypervitaminosis A
0.001 0.860 0.139
M46 Other inflammatory spondylopathies
0.140 0.860 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.139 0.861 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.001 0.861 0.138
M09.2 Juvenile arthritis in ulcerative colitis
0.001 0.861 0.138
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.001 0.861 0.138
M09.0 Juvenile arthritis in psoriasis
0.001 0.861 0.138
E04 Other non-toxic goitre
0.000 0.864 0.136
E70-E90 Metabolic disorders
0.000 0.865 0.135
M05.09 Felty's syndrome (Site unspecified)
0.001 0.865 0.134
M05.08 Felty's syndrome (Other)
0.001 0.865 0.134
M05.07 Felty's syndrome (Ankle and foot)
0.001 0.865 0.134
M05.06 Felty's syndrome (Lower leg)
0.001 0.865 0.134
M05.05 Felty's syndrome (Pelvic region and thigh)
0.001 0.865 0.134
M05.04 Felty's syndrome (Hand)
0.001 0.865 0.134
M05.03 Felty's syndrome (Forearm)
0.001 0.865 0.134
M05.02 Felty's syndrome (Upper arm)
0.001 0.865 0.134
M05.01 Felty's syndrome (Shoulder region)
0.001 0.865 0.134
M05.00 Felty's syndrome (Multiple sites)
0.001 0.865 0.134
M05.19 Rheumatoid lung disease (Site unspecified)
0.001 0.865 0.134
M05.18 Rheumatoid lung disease (Other)
0.001 0.865 0.134
M05.17 Rheumatoid lung disease (Ankle and foot)
0.001 0.865 0.134
M05.16 Rheumatoid lung disease (Lower leg)
0.001 0.865 0.134
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.001 0.865 0.134
M05.14 Rheumatoid lung disease (Hand)
0.001 0.865 0.134
M05.13 Rheumatoid lung disease (Forearm)
0.001 0.865 0.134
M05.12 Rheumatoid lung disease (Upper arm)
0.001 0.865 0.134
M05.11 Rheumatoid lung disease (Shoulder region)
0.001 0.865 0.134
M05.10 Rheumatoid lung disease (Multiple sites)
0.001 0.865 0.134
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.001 0.865 0.134
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.001 0.865 0.134
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.001 0.865 0.134
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.001 0.865 0.134
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.001 0.865 0.134
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.001 0.865 0.134
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.001 0.865 0.134
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.001 0.865 0.134
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.001 0.865 0.134
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.001 0.865 0.134
M08.9 Juvenile arthritis, unspecified
0.001 0.866 0.133
M08.8 Other juvenile arthritis
0.001 0.866 0.133
M08.4 Pauciarticular juvenile arthritis
0.001 0.866 0.133
M08.3 Juvenile polyarthritis (seronegative)
0.001 0.866 0.133
M08.2 Juvenile arthritis with systemic onset
0.001 0.866 0.133
M08.1 Juvenile ankylosing spondylitis
0.001 0.866 0.133
G36 Other acute disseminated demyelination
0.134 0.866 0.000
J33 Nasal polyp
0.000 0.866 0.134
E61 Deficiency of other nutrient elements
0.000 0.866 0.134
M48.8 Other specified spondylopathies
0.133 0.867 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.868 0.132
E50.9 Vitamin A deficiency, unspecified
0.000 0.868 0.132
E50.8 Other manifestations of vitamin A deficiency
0.000 0.868 0.132
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.868 0.132
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.868 0.132
E50.5 Vitamin A deficiency with night blindness
0.000 0.868 0.132
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.868 0.132
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.868 0.132
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.868 0.132
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.868 0.132
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.868 0.132
E63.9 Nutritional deficiency, unspecified
0.000 0.868 0.132
E63.8 Other specified nutritional deficiencies
0.000 0.868 0.132
E63.1 Imbalance of constituents of food intake
0.000 0.868 0.132
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.868 0.132
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.868 0.132
E64.8 Sequelae of other nutritional deficiencies
0.000 0.868 0.132
E64.3 Sequelae of rickets
0.000 0.868 0.132
E64.2 Sequelae of vitamin C deficiency
0.000 0.868 0.132
E64.1 Sequelae of vitamin A deficiency
0.000 0.868 0.132
E64.0 Sequelae of protein-energy malnutrition
0.000 0.868 0.132
J33.9 Nasal polyp, unspecified
0.000 0.868 0.132
M07.38 Other psoriatic arthropathies (Other)
0.000 0.870 0.130
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.870 0.130
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.870 0.130
G37 Other demyelinating diseases of central nervous system
0.129 0.871 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.872 0.127
M08.0 Juvenile rheumatoid arthritis
0.001 0.872 0.127
E51.9 Thiamine deficiency, unspecified
0.000 0.873 0.127
E51.8 Other manifestations of thiamine deficiency
0.000 0.873 0.127
E51.1 Beriberi
0.000 0.873 0.127
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.873 0.127
M12.24 Villonodular synovitis (pigmented) (Hand)
0.000 0.873 0.126
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.873 0.126
E56.9 Vitamin deficiency, unspecified
0.000 0.873 0.126
E56.8 Deficiency of other vitamins
0.000 0.873 0.126
E56.0 Deficiency of vitamin E
0.000 0.873 0.126
E55.0 Rickets, active
0.000 0.874 0.126
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.000 0.876 0.124

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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