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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130695
log Bayes Factor = 47.0743
Chromosome 6   position 31,211,050  (GRCh37) Explore rs3130695 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
K90.0 Coeliac disease
0.000 0.001 0.999
I25.2 Old myocardial infarction
0.000 0.001 0.999
E10.9 Without complications
0.000 0.003 0.997
I22 Subsequent myocardial infarction
0.000 0.005 0.995
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.005 0.995
E83.1 Disorders of iron metabolism
0.993 0.007 0.000
I25.1 Atherosclerotic heart disease
0.000 0.010 0.990
I21 Acute myocardial infarction
0.000 0.010 0.990
E78.5 Hyperlipidaemia, unspecified
0.000 0.019 0.981
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.021 0.979
E14 Unspecified diabetes mellitus
0.000 0.024 0.976
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.030 0.970
I21.9 Acute myocardial infarction, unspecified
0.000 0.032 0.968
E14.9 Without complications
0.000 0.035 0.965
E11.0 With coma
0.000 0.040 0.960
I25.5 Ischaemic cardiomyopathy
0.000 0.043 0.957
I10 Essential (primary) hypertension
0.000 0.045 0.955
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.046 0.954
I10-I15 Hypertensive diseases
0.000 0.056 0.944
E78.2 Mixed hyperlipidaemia
0.000 0.059 0.941
I21.4 Acute subendocardial myocardial infarction
0.000 0.067 0.933
E78.8 Other disorders of lipoprotein metabolism
0.000 0.089 0.911
I12 Hypertensive renal disease
0.000 0.091 0.909
J45.9 Asthma, unspecified
0.000 0.099 0.901
E70-E90 Metabolic disorders
0.000 0.100 0.900
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.102 0.898
I24 Other acute ischaemic heart diseases
0.000 0.106 0.894
I12.9 Hypertensive renal disease without renal failure
0.000 0.118 0.882
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.121 0.879
Chapter IX Diseases of the circulatory system
0.000 0.122 0.878
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.124 0.876
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.139 0.861
I22.8 Subsequent myocardial infarction of other sites
0.000 0.141 0.859
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.150 0.850
L40.8 Other psoriasis
0.000 0.152 0.848
E10.1 With ketoacidosis
0.000 0.159 0.841
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.160 0.840
L40.0 Psoriasis vulgaris
0.000 0.161 0.839
E10.3 With ophthalmic complications
0.000 0.165 0.835
E10.8 With unspecified complications
0.000 0.172 0.828
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.174 0.826
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.177 0.822
E13 Other specified diabetes mellitus
0.000 0.182 0.818
E11.1 With ketoacidosis
0.000 0.195 0.805
E78.4 Other hyperlipidaemia
0.000 0.198 0.802
I20 Angina pectoris
0.000 0.202 0.798
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.207 0.793
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.215 0.785
M06 Other rheumatoid arthritis
0.000 0.215 0.785
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.216 0.784
I23 Certain current complications following acute myocardial infarction
0.000 0.219 0.781
G35-G37 Demyelinating diseases of the central nervous system
0.766 0.234 0.000
I15 Secondary hypertension
0.000 0.235 0.765
E10.5 With peripheral circulatory complications
0.000 0.242 0.758
I24.8 Other forms of acute ischaemic heart disease
0.000 0.249 0.751
E85 Amyloidosis
0.000 0.249 0.751
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.250 0.750
E14.6 With other specified complications
0.000 0.251 0.749
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.265 0.735
L40-L45 Papulosquamous disorders
0.000 0.271 0.729
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.272 0.728
E78.6 Lipoprotein deficiency
0.000 0.274 0.726
E11.2 With renal complications
0.000 0.278 0.722
E10.0 With coma
0.000 0.279 0.721
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.716
E14.1 With ketoacidosis
0.000 0.284 0.716
E10.2 With renal complications
0.000 0.288 0.712
E13.9 Without complications
0.000 0.288 0.712
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.290 0.710
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.292 0.707
I20.0 Unstable angina
0.000 0.293 0.707
E14.5 With peripheral circulatory complications
0.000 0.294 0.706
E10.4 With neurological complications
0.000 0.295 0.705
G37 Other demyelinating diseases of central nervous system
0.705 0.295 0.000
E11.5 With peripheral circulatory complications
0.000 0.296 0.704
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.298 0.702
L40.1 Generalised pustular psoriasis
0.000 0.300 0.700
E14.8 With unspecified complications
0.000 0.300 0.700
E14.7 With multiple complications
0.000 0.300 0.700
E14.2 Withrenal complications
0.000 0.300 0.700
E14.0 With coma
0.000 0.300 0.700
E78.1 Pure hyperglyceridaemia
0.000 0.302 0.698
M06.3 Rheumatoid nodule
0.000 0.304 0.696
I20.9 Angina pectoris, unspecified
0.000 0.307 0.693
M06.4 Inflammatory polyarthropathy
0.000 0.311 0.688
E10.6 With other specified complications
0.000 0.319 0.681
I12.0 Hypertensive renal disease with renal failure
0.000 0.322 0.678
E89.3 Postprocedural hypopituitarism
0.000 0.324 0.676
L43 Lichen planus
0.000 0.333 0.667
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.340 0.660
I11 Hypertensive heart disease
0.000 0.342 0.658
E74 Other disorders of carbohydrate metabolism
0.000 0.344 0.656
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.346 0.654
E88 Other metabolic disorders
0.000 0.350 0.650
I25.3 Aneurysm of heart
0.000 0.351 0.649
G37.9 Demyelinating disease of central nervous system, unspecified
0.645 0.355 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.355 0.645
E77 Disorders of glycoprotein metabolism
0.000 0.355 0.645
E76 Disorders of glycosaminoglycan metabolism
0.000 0.355 0.645
E72 Other disorders of amino-acid metabolism
0.000 0.355 0.645
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.355 0.645
E70 Disorders of aromatic amino-acid metabolism
0.000 0.355 0.645
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.355 0.645
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.359 0.641
I15.9 Seconday hypertension, unspecified
0.000 0.362 0.638
E84 Cystic fibrosis
0.000 0.364 0.636
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.371 0.629
I23.8 Other current complications following acute myocardial infarction
0.000 0.376 0.624
E40-E46 Malnutrition
0.000 0.380 0.620
L43.9 Lichen planus, unspecified
0.000 0.380 0.620
E14.3 With ophthalmic complications
0.000 0.381 0.619
L40.3 Pustulosis palmaris et plantaris
0.000 0.382 0.617
I85 Oesophageal varices
0.000 0.385 0.615
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.387 0.613
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.390 0.610
E85.4 Organ-limited amyloidosis
0.000 0.390 0.610
E11.6 With other specified complications
0.000 0.399 0.601
I85.9 Oesophageal varices without bleeding
0.000 0.408 0.592
G36 Other acute disseminated demyelination
0.592 0.408 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.410 0.590
E13.8 With unspecified complications
0.000 0.413 0.587
E13.7 With multiple complications
0.000 0.413 0.587
E13.6 With other specified complications
0.000 0.413 0.587
E13.5 With peripheral circulatory complications
0.000 0.413 0.587
E13.4 With neurological complications
0.000 0.413 0.587
E13.2 With renal complications
0.000 0.413 0.587
E13.1 With ketoacidosis
0.000 0.413 0.587
E13.0 With coma
0.000 0.413 0.587
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.414 0.586
I87 Other disorders of veins
0.000 0.415 0.585
I13 Hypertensive heart and renal disease
0.000 0.415 0.585
E85.9 Amyloidosis, unspecified
0.000 0.416 0.584
M45 Ankylosing spondylitis
0.000 0.421 0.579
I81 Portal vein thrombosis
0.000 0.422 0.578
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.423 0.577
E16 Other disorders of pancreatic internal secretion
0.000 0.429 0.571
I00-I02 Acute rheumatic fever
0.000 0.429 0.571
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.431 0.569
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.433 0.567
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.437 0.563
M06.2 Rheumatoid bursitis
0.000 0.437 0.563
M06.1 Adult-onset Still's disease
0.000 0.437 0.563
M06.34 Rheumatoid nodule (Hand)
0.000 0.438 0.562
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.440 0.560
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.440 0.560
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.440 0.560
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.440 0.560
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.440 0.560
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.440 0.560
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.440 0.560
G37.8 Other specified demyelinating diseases of central nervous system
0.556 0.444 0.000
I15.8 Other secondary hypertension
0.000 0.452 0.548
I15.2 Hypertension secondary to endocrine disorders
0.000 0.452 0.548
I15.0 Renovascular hypertension
0.000 0.452 0.548
I25.4 Coronary artery aneurysm
0.000 0.453 0.547
E85.3 Secondary systemic amyloidosis
0.000 0.455 0.545
I15.1 Hypertension secondary to other renal disorders
0.000 0.455 0.545
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.456 0.544
E73 Lactose intolerance
0.000 0.461 0.538
E85.8 Other amyloidosis
0.000 0.462 0.538
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.462 0.538
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.462 0.538
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.462 0.538
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.464 0.536
E13.3 With ophthalmic complications
0.000 0.466 0.534
I87.1 Compression of vein
0.000 0.466 0.534
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.468 0.532
E11.8 With unspecified complications
0.000 0.469 0.531
I86 Varicose veins of other sites
0.000 0.471 0.529
I20.1 Angina pectoris with documented spasm
0.000 0.473 0.527
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.473 0.527
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.473 0.527
E89.5 Postprocedural testicular hypofunction
0.000 0.473 0.527
E89.1 Postprocedural hypoinsulinaemia
0.000 0.473 0.527
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.474 0.526
E14.4 With neurological complications
0.000 0.476 0.524
L44 Other papulosquamous disorders
0.000 0.477 0.522
L41 Parapsoriasis
0.000 0.477 0.522
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.477 0.522
E11.4 With neurological complications
0.000 0.479 0.521
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
L42 Pityriasis rosea
0.000 0.487 0.513
E89.4 Postprocedural ovarian failure
0.000 0.491 0.509
M06.8 Other specified rheumatoid arthritis
0.000 0.492 0.508
E15 Nondiabetic hypoglycaemic coma
0.000 0.493 0.507
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.493 0.507
G37.5 Concentric sclerosis [Balo]
0.505 0.495 0.000
G37.4 Subacute necrotising myelitis
0.505 0.495 0.000
G37.2 Central pontine myelinolysis
0.505 0.495 0.000
G37.1 Central demyelination of corpus callosum
0.505 0.495 0.000
G37.0 Diffuse sclerosis
0.505 0.495 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.505 0.495 0.000
E16.1 Other hypoglycaemia
0.000 0.499 0.501
E50-E64 Other nutritional deficiencies
0.000 0.500 0.500
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.501 0.499
M06.38 Rheumatoid nodule (Other)
0.000 0.501 0.499
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.501 0.499
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.501 0.499
M06.33 Rheumatoid nodule (Forearm)
0.000 0.501 0.499
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.501 0.499
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.501 0.499
E88.8 Other specified metabolic disorders
0.000 0.501 0.498
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.503 0.497
E83 Disorders of mineral metabolism
0.184 0.503 0.312
I86.4 Gastric varices
0.000 0.506 0.494
L43.8 Other lichen planus
0.000 0.506 0.494
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.506 0.494
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.506 0.494
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.506 0.494
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.506 0.494
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.506 0.494
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.506 0.494
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.506 0.494
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.506 0.494
I89.1 Lymphangitis
0.000 0.509 0.491
L43.3 Subacute (active) lichen planus
0.000 0.521 0.479
L43.2 Lichenoid drug reaction
0.000 0.521 0.479
L43.1 Bullous lichen planus
0.000 0.521 0.479
L43.0 Hypertrophic lichen planus
0.000 0.521 0.479
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.529 0.470
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.529 0.470
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.529 0.470
E74.2 Disorders of galactose metabolism
0.000 0.529 0.470
E74.1 Disorders of fructose metabolism
0.000 0.529 0.470
I87.8 Other specified disorders of veins
0.000 0.532 0.468
E88.2 Lipomatosis, not elsewhere classified
0.000 0.533 0.467
G36.0 Neuromyelitis optica [Devic]
0.467 0.533 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.534 0.466
E88.3 Tumour lysis syndrome
0.000 0.534 0.466
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.537 0.463
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.537 0.463
E70.3 Albinism
0.000 0.537 0.463
E70.2 Disorders of tyrosine metabolism
0.000 0.537 0.463
E70.1 Other hyperphenylalaninaemias
0.000 0.537 0.463
E70.0 Classical phenylketonuria
0.000 0.537 0.463
E71.3 Disorders of fatty-acid metabolism
0.000 0.537 0.463
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.537 0.463
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.537 0.463
E71.0 Maple-syrup-urine disease
0.000 0.537 0.463
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.537 0.463
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.537 0.463
E72.5 Disorders of glycine metabolism
0.000 0.537 0.463
E72.4 Disorders of ornithine metabolism
0.000 0.537 0.463
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.537 0.463
E72.2 Disorders of urea cycle metabolism
0.000 0.537 0.463
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.537 0.463
E72.0 Disorders of amino-acid transport
0.000 0.537 0.463
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.537 0.463
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.537 0.463
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.537 0.463
E76.2 Other mucopolysaccharidoses
0.000 0.537 0.463
E76.1 Mucopolysaccharidosis, type II
0.000 0.537 0.463
E76.0 Mucopolysaccharidosis, type I
0.000 0.537 0.463
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.537 0.463
E77.8 Other disorders of glycoprotein metabolism
0.000 0.537 0.463
E77.1 Defects in glycoprotein degradation
0.000 0.537 0.463
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.537 0.463
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.537 0.463
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.537 0.463
E79.1 Lesch-Nyhan syndrome
0.000 0.537 0.463
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.537 0.463
I88 Nonspecific lymphadenitis
0.000 0.538 0.462
E84.8 Cystic fibrosis with other manifestations
0.000 0.544 0.456
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.544 0.456
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.544 0.456
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.544 0.456
K90 Intestinal malabsorption
0.000 0.550 0.450
E84.9 Cystic fibrosis, unspecified
0.000 0.553 0.447
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.555 0.445
E45 Retarded development following protein-energy malnutrition
0.000 0.555 0.445
E43 Unspecified severe protein-energy malnutrition
0.000 0.555 0.445
E42 Marasmic kwashiorkor
0.000 0.555 0.445
E41 Nutritional marasmus
0.000 0.555 0.445
E40 Kwashiorkor
0.000 0.555 0.445
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.560 0.440
I89.0 Lymphoedema, not elsewhere classified
0.000 0.562 0.438
E75.6 Lipid storage disorder, unspecified
0.000 0.562 0.437
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.562 0.437
E75.3 Sphingolipidosis, unspecified
0.000 0.562 0.437
E75.2 Other sphingolipidosis
0.000 0.562 0.437
E75.1 Other gangliosidosis
0.000 0.562 0.437
E75.0 GM2 gangliosidosis
0.000 0.562 0.437
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.572 0.428
I24.1 Dressler's syndrome
0.001 0.573 0.427
G36.9 Acute disseminated demyelination, unspecified
0.424 0.576 0.000
G36.8 Other specified acute disseminated demyelination
0.424 0.576 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.424 0.576 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.578 0.421
I87.9 Disorder of vein, unspecified
0.000 0.580 0.420
I87.0 Postphlebitic syndrome
0.000 0.580 0.420
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.580 0.419
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.580 0.419
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.580 0.419
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.585 0.415
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.585 0.415
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.585 0.415
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.585 0.415
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.585 0.415
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.585 0.415
M06.0 Seronegative rheumatoid arthritis
0.000 0.586 0.414
E16.2 Hypoglycaemia, unspecified
0.000 0.590 0.410
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.590 0.410
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.590 0.410
E16.4 Abnormal secretion of gastrin
0.000 0.590 0.410
E16.3 Increased secretion of glucagon
0.000 0.590 0.410
I02 Rheumatic chorea
0.000 0.591 0.409
I01 Rheumatic fever with heart involvement
0.000 0.591 0.409
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.596 0.403
M06.18 Adult-onset Still's disease (Other)
0.000 0.596 0.403
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.596 0.403
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.596 0.403
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.596 0.403
M06.14 Adult-onset Still's disease (Hand)
0.000 0.596 0.403
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.596 0.403
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.596 0.403
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.596 0.403
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.596 0.403
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.596 0.403
M06.28 Rheumatoid bursitis (Other)
0.000 0.596 0.403
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.596 0.403
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.596 0.403
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.596 0.403
M06.24 Rheumatoid bursitis (Hand)
0.000 0.596 0.403
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.596 0.403
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.596 0.403
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.596 0.403
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.596 0.403
E65-E68 Obesity and other hyperalimentation
0.000 0.596 0.403
E75.5 Other lipid storage disorders
0.000 0.597 0.402
I85.0 Oesophageal varices with bleeding
0.000 0.601 0.399
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.608 0.392
E11.3 With ophthalmic complications
0.000 0.611 0.389
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.613 0.387
E73.8 Other lactose intolerance
0.000 0.614 0.386
E73.1 Secondary lactase deficiency
0.000 0.614 0.386
E73.0 Congenital lactase deficiency
0.000 0.614 0.386
E74.0 Glycogen storage disease
0.000 0.615 0.385
I86.2 Pelvic varices
0.000 0.620 0.379
I86.0 Sublingual varices
0.000 0.620 0.379
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.621 0.379
L41.9 Parapsoriasis, unspecified
0.000 0.625 0.375
L41.8 Other parapsoriasis
0.000 0.625 0.375
L41.5 Retiform parapsoriasis
0.000 0.625 0.375
L41.4 Large plaque parapsoriasis
0.000 0.625 0.375
L41.3 Small plaque parapsoriasis
0.000 0.625 0.375
L41.2 Lymphomatoid papulosis
0.000 0.625 0.375
L41.1 Pityriasis lichenoides chronica
0.000 0.625 0.375
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.625 0.375
L44.9 Papulosquamous disorder, unspecified
0.000 0.625 0.375
L44.8 Other specified papulosquamous disorders
0.000 0.625 0.375
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.625 0.375
L44.3 Lichen ruber moniliformis
0.000 0.625 0.375
L44.2 Lichen striatus
0.000 0.625 0.375
L44.1 Lichen nitidus
0.000 0.625 0.375
L44.0 Pityriasis rubra pilaris
0.000 0.625 0.375
I05-I09 Chronic rheumatic heart diseases
0.000 0.627 0.373
E55 Vitamin D deficiency
0.000 0.632 0.368
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.635 0.364
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.635 0.364
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.635 0.364
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.635 0.364
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.635 0.364
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.635 0.364
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.635 0.364
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.635 0.364
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.635 0.364
E51 Thiamine deficiency
0.000 0.636 0.364
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.638 0.362
M05-M14 Inflammatory polyarthropathies
0.000 0.640 0.360
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.641 0.359
E63 Other nutritional deficiencies
0.000 0.641 0.359
E56 Other vitamin deficiencies
0.000 0.641 0.359
E50 Vitamin A deficiency
0.000 0.641 0.359
E60 Dietary zinc deficiency
0.000 0.641 0.359
E59 Dietary selenium deficiency
0.000 0.641 0.359
E58 Dietary calcium deficiency
0.000 0.641 0.359
E54 Ascorbic acid deficiency
0.000 0.641 0.359
E52 Niacin deficiency [pellagra]
0.000 0.641 0.359
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.643 0.357
E61 Deficiency of other nutrient elements
0.000 0.643 0.357
E20-E35 Disorders of other endocrine glands
0.000 0.644 0.356
E83.9 Disorder of mineral metabolism, unspecified
0.132 0.644 0.224
E83.8 Other disorders of mineral metabolism
0.132 0.644 0.224
E83.2 Disorders of zinc metabolism
0.132 0.644 0.224
E83.0 Disorders of copper metabolism
0.132 0.644 0.224
I00 Rheumatic fever without mention of heart involvement
0.000 0.650 0.350
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.654 0.346
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.655 0.345
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.660 0.340
K90.8 Other intestinal malabsorption
0.000 0.665 0.335
I86.1 Scrotal varices
0.000 0.667 0.333
I88.8 Other nonspecific lymphadenitis
0.000 0.668 0.331
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.668 0.331
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.668 0.331
M07 Psoriatic and enteropathic arthropathies
0.000 0.671 0.329
I86.8 Varicose veins of other specified sites
0.000 0.672 0.328
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.001 0.672 0.327
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.676 0.324
K90.3 Pancreatic steatorrhoea
0.000 0.677 0.323
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.677 0.323
K90.1 Tropical sprue
0.000 0.677 0.323
I27 Other pulmonary heart diseases
0.000 0.680 0.320
E44.1 Mild protein-energy malnutrition
0.000 0.681 0.319
E44.0 Moderate protein-energy malnutrition
0.000 0.681 0.319
M05 Seropositive rheumatoid arthritis
0.000 0.685 0.315
M07.3 Other psoriatic arthropathies
0.000 0.687 0.313
I86.3 Vulval varices
0.000 0.689 0.311
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.690 0.310
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.693 0.307
E80.5 Crigler-Najjar syndrome
0.000 0.693 0.307
E80.3 Defects of catalase and peroxydase
0.000 0.693 0.307
E80.1 Porphyria cutanea tarda
0.000 0.693 0.307
E80.0 Hereditary erythropoietic porphyria
0.000 0.693 0.307
E80.6 Other disorders of bilirubin metabolism
0.000 0.694 0.306
I28 Other diseases of pulmonary vessels
0.000 0.695 0.305
E22 Hyperfunction of pituitary gland
0.000 0.698 0.302
E80.2 Other porphyria
0.000 0.701 0.298
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.703 0.297
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.703 0.297
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.703 0.297
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.703 0.297
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.703 0.297
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.703 0.297
E28 Ovarian dysfunction
0.000 0.705 0.294
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.706 0.293
I01.8 Other acute rheumatic heart disease
0.000 0.706 0.293
I01.2 Acute rheumatic myocarditis
0.000 0.706 0.293
I01.1 Acute rheumatic endocarditis
0.000 0.706 0.293
I01.0 Acute rheumatic pericarditis
0.000 0.706 0.293
I02.9 Rheumatic chorea without heart involvement
0.000 0.706 0.293
I02.0 Rheumatic chorea with heart involvement
0.000 0.706 0.293
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.707 0.293
K90.9 Intestinal malabsorption, unspecified
0.000 0.709 0.291
E83.4 Disorders of magnesium metabolism
0.038 0.710 0.252
E67 Other hyperalimentation
0.000 0.710 0.289
E68 Sequelae of hyperalimentation
0.000 0.710 0.289
E83.3 Disorders of phosphorus metabolism
0.111 0.712 0.177
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.712 0.288
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.715 0.285
E73.9 Lactose intolerance, unspecified
0.001 0.721 0.279
I82 Other venous embolism and thrombosis
0.000 0.722 0.278
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.725 0.275
E55.9 Vitamin D deficiency, unspecified
0.000 0.726 0.274
I99 Other and unspecified disorders of circulatory system
0.000 0.727 0.273
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.729 0.271
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.729 0.271
E65 Localised adiposity
0.000 0.731 0.269
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.732 0.268
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.733 0.267
E51.2 Wernicke's encephalopathy
0.000 0.733 0.266
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.735 0.265
I27.9 Pulmonary heart disease, unspecified
0.000 0.735 0.265
I27.2 Other secondary pulmonary hypertension
0.000 0.735 0.265
E55.0 Rickets, active
0.000 0.736 0.264
E23 Hypofunction and other disorders of pituitary gland
0.000 0.736 0.264
E51.9 Thiamine deficiency, unspecified
0.000 0.739 0.261
E51.8 Other manifestations of thiamine deficiency
0.000 0.739 0.261
E51.1 Beriberi
0.000 0.739 0.261
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.741 0.258
M08 Juvenile arthritis
0.000 0.741 0.258
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.742 0.258
I08 Multiple valve diseases
0.000 0.742 0.258
E50.9 Vitamin A deficiency, unspecified
0.000 0.742 0.257
E50.8 Other manifestations of vitamin A deficiency
0.000 0.742 0.257
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.742 0.257
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.742 0.257
E50.5 Vitamin A deficiency with night blindness
0.000 0.742 0.257
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.742 0.257
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.742 0.257
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.742 0.257

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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