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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130724
log Bayes Factor = 94.9138
Chromosome 6   position 29,118,530  (GRCh37) Explore rs3130724 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.996 0.004 0.000
E16.2 Hypoglycaemia, unspecified
0.991 0.009 0.000
E03 Other hypothyroidism
0.979 0.021 0.000
E10.2 With renal complications
0.976 0.024 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.973 0.027 0.000
E03.9 Hypothyroidism, unspecified
0.959 0.041 0.000
E40-E46 Malnutrition
0.892 0.108 0.000
E10.1 With ketoacidosis
0.878 0.122 0.000
E10.4 With neurological complications
0.874 0.126 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.874 0.126 0.000
N40 Hyperplasia of prostate
0.000 0.165 0.835
E16.1 Other hypoglycaemia
0.833 0.167 0.000
E46 Unspecified protein-energy malnutrition
0.815 0.185 0.000
E14 Unspecified diabetes mellitus
0.812 0.188 0.000
E13 Other specified diabetes mellitus
0.808 0.192 0.000
E10.7 With multiple complications
0.790 0.210 0.000
E10.0 With coma
0.777 0.223 0.000
E10.6 With other specified complications
0.762 0.238 0.000
E10.5 With peripheral circulatory complications
0.746 0.254 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.739 0.261 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.722 0.277 0.000
E03.8 Other specified hypothyroidism
0.721 0.279 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
E14.3 With ophthalmic complications
0.706 0.294 0.000
E03.5 Myxoedema coma
0.702 0.298 0.000
E03.4 Atrophy of thyroid (acquired)
0.702 0.298 0.000
E03.3 Postinfectious hypothyroidism
0.702 0.298 0.000
E03.1 Congenital hypothyroidism without goitre
0.702 0.298 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.300 0.700
E50-E64 Other nutritional deficiencies
0.681 0.319 0.000
E14.1 With ketoacidosis
0.675 0.325 0.000
E05.8 Other thyrotoxicosis
0.663 0.337 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.656 0.344 0.000
E13.9 Without complications
0.648 0.352 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.640 0.360 0.000
E45 Retarded development following protein-energy malnutrition
0.640 0.360 0.000
E43 Unspecified severe protein-energy malnutrition
0.640 0.360 0.000
E42 Marasmic kwashiorkor
0.640 0.360 0.000
E41 Nutritional marasmus
0.640 0.360 0.000
E40 Kwashiorkor
0.640 0.360 0.000
E10.8 With unspecified complications
0.623 0.377 0.000
E14.6 With other specified complications
0.613 0.387 0.000
E13.3 With ophthalmic complications
0.610 0.390 0.000
E14.4 With neurological complications
0.607 0.393 0.000
E07 Other disorders of thyroid
0.602 0.398 0.000
E14.8 With unspecified complications
0.594 0.406 0.000
E14.2 Withrenal complications
0.590 0.410 0.000
E14.7 With multiple complications
0.582 0.418 0.000
E14.0 With coma
0.582 0.418 0.000
E13.8 With unspecified complications
0.579 0.421 0.000
E13.7 With multiple complications
0.579 0.421 0.000
E13.6 With other specified complications
0.579 0.421 0.000
E13.5 With peripheral circulatory complications
0.579 0.421 0.000
E13.4 With neurological complications
0.579 0.421 0.000
E13.2 With renal complications
0.579 0.421 0.000
E13.1 With ketoacidosis
0.579 0.421 0.000
E13.0 With coma
0.579 0.421 0.000
E06 Thyroiditis
0.578 0.422 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.577 0.423 0.000
E14.5 With peripheral circulatory complications
0.568 0.432 0.000
K90 Intestinal malabsorption
0.568 0.432 0.000
Z46.6 Fitting and adjustment of urinary device
0.000 0.450 0.550
N40-N51 Diseases of male genital organs
0.000 0.473 0.527
K40 Inguinal hernia
0.000 0.477 0.523
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
N42 Other disorders of prostate
0.000 0.488 0.512
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.494 0.506
N41 Inflammatory diseases of prostate
0.000 0.496 0.504
E58 Dietary calcium deficiency
0.503 0.497 0.000
E55 Vitamin D deficiency
0.500 0.500 0.000
E56 Other vitamin deficiencies
0.500 0.500 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.505 0.495
E51 Thiamine deficiency
0.492 0.508 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.511 0.489
E64 Sequelae of malnutrition and other nutritional deficiencies
0.488 0.512 0.000
E63 Other nutritional deficiencies
0.488 0.512 0.000
E50 Vitamin A deficiency
0.488 0.512 0.000
E60 Dietary zinc deficiency
0.488 0.512 0.000
E59 Dietary selenium deficiency
0.488 0.512 0.000
E54 Ascorbic acid deficiency
0.488 0.512 0.000
E52 Niacin deficiency [pellagra]
0.488 0.512 0.000
N42.8 Other specified disorders of prostate
0.000 0.514 0.486
E11 Non-insulin-dependent diabetes mellitus
0.482 0.518 0.000
E11.5 With peripheral circulatory complications
0.464 0.536 0.000
E61 Deficiency of other nutrient elements
0.462 0.537 0.000
E07.8 Other specified disorders of thyroid
0.460 0.540 0.000
E44.1 Mild protein-energy malnutrition
0.459 0.541 0.000
E44.0 Moderate protein-energy malnutrition
0.459 0.541 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.456 0.544 0.000
K90.8 Other intestinal malabsorption
0.453 0.547 0.000
E06.9 Thyroiditis, unspecified
0.434 0.565 0.000
E07.1 Dyshormogenetic goitre
0.432 0.568 0.000
E07.0 Hypersecretion of calcitonin
0.432 0.568 0.000
N46 Male infertility
0.000 0.569 0.430
E06.5 Other chronic thyroiditis
0.427 0.573 0.000
E53 Deficiency of other B group vitamins
0.425 0.574 0.000
E06.4 Drug-induced thyroiditis
0.414 0.585 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.414 0.585 0.000
E06.1 Subacute thyroiditis
0.414 0.585 0.000
E06.0 Acute thyroiditis
0.414 0.585 0.000
K90.3 Pancreatic steatorrhoea
0.407 0.593 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.407 0.593 0.000
K90.1 Tropical sprue
0.407 0.593 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.600 0.400
N44 Torsion of testis
0.000 0.605 0.395
N41.0 Acute prostatitis
0.000 0.612 0.388
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.622 0.378
K90.9 Intestinal malabsorption, unspecified
0.377 0.622 0.000
E11.3 With ophthalmic complications
0.376 0.624 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.625 0.375
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.625 0.375
N42.0 Calculus of prostate
0.000 0.628 0.372
N42.2 Atrophy of prostate
0.000 0.629 0.371
E55.9 Vitamin D deficiency, unspecified
0.371 0.629 0.000
E56.1 Deficiency of vitamin K
0.370 0.630 0.000
N42.3 Dysplasia of prostate
0.000 0.633 0.367
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.636 0.363
N41.3 Prostatocystitis
0.000 0.638 0.362
N41.2 Abscess of prostate
0.000 0.638 0.362
E55.0 Rickets, active
0.359 0.641 0.000
E56.9 Vitamin deficiency, unspecified
0.358 0.641 0.000
E56.8 Deficiency of other vitamins
0.358 0.641 0.000
E56.0 Deficiency of vitamin E
0.358 0.641 0.000
E51.2 Wernicke's encephalopathy
0.357 0.643 0.000
E51.9 Thiamine deficiency, unspecified
0.353 0.647 0.000
E51.8 Other manifestations of thiamine deficiency
0.353 0.647 0.000
E51.1 Beriberi
0.353 0.647 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.649 0.351
E50.9 Vitamin A deficiency, unspecified
0.350 0.650 0.000
E50.8 Other manifestations of vitamin A deficiency
0.350 0.650 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.350 0.650 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.350 0.650 0.000
E50.5 Vitamin A deficiency with night blindness
0.350 0.650 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.350 0.650 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.350 0.650 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.350 0.650 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.350 0.650 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.350 0.650 0.000
E63.9 Nutritional deficiency, unspecified
0.350 0.650 0.000
E63.8 Other specified nutritional deficiencies
0.350 0.650 0.000
E63.1 Imbalance of constituents of food intake
0.350 0.650 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.350 0.650 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.350 0.650 0.000
E64.8 Sequelae of other nutritional deficiencies
0.350 0.650 0.000
E64.3 Sequelae of rickets
0.350 0.650 0.000
E64.2 Sequelae of vitamin C deficiency
0.350 0.650 0.000
E64.1 Sequelae of vitamin A deficiency
0.350 0.650 0.000
E64.0 Sequelae of protein-energy malnutrition
0.350 0.650 0.000
E61.1 Iron deficiency
0.348 0.652 0.000
E11.0 With coma
0.346 0.654 0.000
E11.7 With multiple complications
0.346 0.654 0.000
E65-E68 Obesity and other hyperalimentation
0.334 0.665 0.000
E61.9 Deficiency of nutrient element, unspecified
0.332 0.668 0.000
E61.8 Deficiency of other specified nutrient elements
0.332 0.668 0.000
E61.7 Deficiency of multiple nutrient elements
0.332 0.668 0.000
E61.6 Vanadium deficiency
0.332 0.668 0.000
E61.5 Molybdenum deficiency
0.332 0.668 0.000
E61.4 Chromium deficiency
0.332 0.668 0.000
E61.3 Manganese deficiency
0.332 0.668 0.000
E61.0 Copper deficiency
0.332 0.668 0.000
E11.1 With ketoacidosis
0.322 0.678 0.000
E11.6 With other specified complications
0.316 0.684 0.000
E53.1 Pyridoxine deficiency
0.305 0.695 0.000
E53.0 Riboflavin deficiency
0.305 0.695 0.000
E11.8 With unspecified complications
0.293 0.707 0.000
E53.8 Deficiency of other specified B group vitamins
0.284 0.716 0.000
E61.2 Magnesium deficiency
0.284 0.716 0.000
T39.1 4-Aminophenol derivatives
0.000 0.724 0.276
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.725 0.275
N45 Orchitis and epididymitis
0.000 0.729 0.271
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.729 0.271
N51.2 Balanitis in diseases classified elsewhere
0.000 0.729 0.271
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.729 0.271
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.729 0.271
N49.2 Inflammatory disorders of scrotum
0.000 0.729 0.271
E53.9 Vitamin B deficiency, unspecified
0.269 0.730 0.000
T42.4 Benzodiazepines
0.000 0.735 0.265
E11.2 With renal complications
0.262 0.738 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.739 0.261
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.739 0.261
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.739 0.261
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.739 0.261
E07.9 Disorder of thyroid, unspecified
0.261 0.739 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.739 0.261
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.745 0.255
T39.0 Salicylates
0.000 0.747 0.253
N41.1 Chronic prostatitis
0.000 0.750 0.250
E67 Other hyperalimentation
0.240 0.760 0.000
E68 Sequelae of hyperalimentation
0.240 0.760 0.000
K75.4 Autoimmune hepatitis
0.236 0.764 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.764 0.236
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.766 0.234
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.767 0.233
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.770 0.230
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.775 0.225
K75 Other inflammatory liver diseases
0.223 0.777 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.786 0.214
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.791 0.209
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.795 0.205
E06.3 Autoimmune thyroiditis
0.204 0.795 0.000
T36 Poisoning by systemic antibiotics
0.000 0.798 0.202
N50 Other disorders of male genital organs
0.000 0.798 0.202
K75.9 Inflammatory liver disease, unspecified
0.200 0.800 0.000
E20-E35 Disorders of other endocrine glands
0.199 0.801 0.000
T39.4 Antirheumatics, not elsewhere classified
0.000 0.802 0.197
T39.2 Pyrazolone derivatives
0.000 0.802 0.197
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.805 0.195
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.810 0.190
K75.8 Other specified inflammatory liver diseases
0.189 0.811 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.812 0.188
T42.3 Barbiturates
0.000 0.812 0.188
T42.2 Succinimides and oxazolidinediones
0.000 0.812 0.188
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.813 0.187
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.813 0.187
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.813 0.187
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.813 0.187
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.819 0.181
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.820 0.180
N43 Hydrocele and spermatocele
0.000 0.823 0.177
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.823 0.177
T43.2 Other and unspecified antidepressants
0.000 0.825 0.175
K70-K77 Diseases of liver
0.173 0.827 0.000
E67.8 Other specified hyperalimentation
0.172 0.828 0.000
E67.3 Hypervitaminosis D
0.172 0.828 0.000
E67.2 Megavitamin-B6 syndrome
0.172 0.828 0.000
E67.1 Hypercarotenaemia
0.172 0.828 0.000
E67.0 Hypervitaminosis A
0.172 0.828 0.000
T42.0 Hydantoin derivatives
0.000 0.828 0.172
T42.1 Iminostilbenes
0.000 0.828 0.172
E65 Localised adiposity
0.169 0.831 0.000
E27 Other disorders of adrenal gland
0.169 0.831 0.000
E27.1 Primary adrenocortical insufficiency
0.167 0.833 0.000
T50.8 Diagnostic agents
0.000 0.833 0.167
T50.7 Analeptics and opioid receptor antagonists
0.000 0.833 0.167
T50.5 Appetite depressants
0.000 0.833 0.167
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.833 0.167
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.833 0.167
T50.1 Loop [high-ceiling] diuretics
0.000 0.833 0.167
T50.0 Mineralocorticoids and their antagonists
0.000 0.833 0.167
N20.0 Calculus of kidney
0.000 0.833 0.167
K75.0 Abscess of liver
0.166 0.834 0.000
N50.9 Disorder of male genital organs, unspecified
0.000 0.834 0.166
T50.4 Drugs affecting uric acid metabolism
0.000 0.835 0.165
K72 Hepatic failure, not elsewhere classified
0.164 0.836 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.836 0.164
E24 Cushing's syndrome
0.164 0.836 0.000
T43.6 Psychostimulants with abuse potential
0.000 0.837 0.163
T43.9 Psychotropic drug, unspecified
0.000 0.839 0.161
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.839 0.161
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.839 0.161
K75.2 Nonspecific reactive hepatitis
0.160 0.840 0.000
K75.1 Phlebitis of portal vein
0.160 0.840 0.000
T36.0 Penicillins
0.000 0.840 0.159
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.841 0.159
K73 Chronic hepatitis, not elsewhere classified
0.158 0.842 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.845 0.155
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.848 0.152
E14.9 Without complications
0.150 0.850 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.149 0.850 0.000
K72.9 Hepatic failure, unspecified
0.147 0.853 0.000
E25 Adrenogenital disorders
0.146 0.854 0.000
T36.9 Systemic antibiotic, unspecified
0.000 0.855 0.145
T36.8 Other systemic antibiotics
0.000 0.855 0.145
T36.7 Antifungal antibiotics, systemically used
0.000 0.855 0.145
T36.6 Rifamycins
0.000 0.855 0.145
T36.5 Aminoglycosides
0.000 0.855 0.145
T36.4 Tetracyclines
0.000 0.855 0.145
T36.3 Macrolides
0.000 0.855 0.145
T36.2 Chloramphenicol group
0.000 0.855 0.145
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.855 0.145
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.855 0.145
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.855 0.144
T45.2 Vitamins, not elsewhere classified
0.000 0.856 0.144
K72.0 Acute and subacute hepatic failure
0.144 0.856 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.143 0.857 0.000
E32 Diseases of thymus
0.143 0.857 0.000
E31 Polyglandular dysfunction
0.143 0.857 0.000
E30 Disorders of puberty, not elsewhere classified
0.143 0.857 0.000
E20 Hypoparathyroidism
0.143 0.857 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.858 0.141
K73.9 Chronic hepatitis, unspecified
0.141 0.859 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.860 0.140
N48 Other disorders of penis
0.000 0.861 0.139
T45.5 Anticoagulants
0.000 0.861 0.139
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.863 0.137
T45.8 Other primarily systemic and haematological agents
0.000 0.863 0.137
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.863 0.137
T45.6 Fibrinolysis-affecting drugs
0.000 0.863 0.137
T45.4 Iron and its compounds
0.000 0.863 0.137
T45.3 Enzymes, not elsewhere classified
0.000 0.863 0.137
E28 Ovarian dysfunction
0.135 0.865 0.000
E24.2 Drug-induced Cushing's syndrome
0.135 0.865 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.866 0.134
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.866 0.134
T37.5 Antiviral drugs
0.000 0.866 0.134
T37.4 Anthelminthics
0.000 0.866 0.134
T37.3 Other antiprotozoal drugs
0.000 0.866 0.134
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.866 0.134
T37.1 Antimycobacterial drugs
0.000 0.866 0.134
T37.0 Sulphonamides
0.000 0.866 0.134
T41.5 Therapeutic gases
0.000 0.866 0.134
T41.4 Anaesthetic, unspecified
0.000 0.866 0.134
T41.3 Local anaesthetics
0.000 0.866 0.134
T41.2 Other and unspecified general anaesthetics
0.000 0.866 0.134
T41.1 Intravenous anaesthetics
0.000 0.866 0.134
T41.0 Inhaled anaesthetics
0.000 0.866 0.134
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.866 0.134
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.866 0.134
T48.5 Anti-common-cold drugs
0.000 0.866 0.134
T48.4 Expectorants
0.000 0.866 0.134
T48.3 Antitussives
0.000 0.866 0.134
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.866 0.134
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.866 0.134
T48.0 Oxytocic drugs
0.000 0.866 0.134
T49.9 Topical agent, unspecified
0.000 0.866 0.134
T49.8 Other topical agents
0.000 0.866 0.134
T49.7 Dental drugs, topically applied
0.000 0.866 0.134
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.866 0.134
T49.5 Ophthalmological drugs and preparations
0.000 0.866 0.134
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.866 0.134
T49.3 Emollients, demulcents and protectants
0.000 0.866 0.134
T49.2 Local astringents and local detergents
0.000 0.866 0.134
T49.1 Antipruritics
0.000 0.866 0.134
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.866 0.134
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.868 0.132
E26 Hyperaldosteronism
0.132 0.868 0.000
E24.0 Pituitary-dependent Cushing's disease
0.130 0.870 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.130 0.870 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.870 0.130
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.870 0.130
T47.7 Emetics
0.000 0.870 0.130
T47.6 Antidiarrhoeal drugs
0.000 0.870 0.130
T47.5 Digestants
0.000 0.870 0.130
T47.3 Saline and osmotic laxatives
0.000 0.870 0.130
T47.2 Stimulant laxatives
0.000 0.870 0.130
T47.0 Histamine H(2)-receptor antagonists
0.000 0.870 0.130
N50.0 Atrophy of testis
0.000 0.870 0.130
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.871 0.128
N43.1 Infected hydrocele
0.000 0.872 0.127
N43.0 Encysted hydrocele
0.000 0.872 0.127
K71 Toxic liver disease
0.127 0.873 0.000
K72.1 Chronic hepatic failure
0.126 0.873 0.000
E04 Other non-toxic goitre
0.126 0.873 0.000
K70 Alcoholic liver disease
0.126 0.874 0.000
N48.1 Balanoposthitis
0.000 0.874 0.126
E83 Disorders of mineral metabolism
0.018 0.875 0.107
K77 Liver disorders in diseases classified elsewhere
0.124 0.876 0.000
N43.2 Other hydrocele
0.000 0.876 0.124
T45.0 Antiallergic and antiemetic drugs
0.000 0.877 0.123
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.001 0.878 0.121
E27.5 Adrenomedullary hyperfunction
0.121 0.879 0.000
E27.0 Other adrenocortical overactivity
0.121 0.879 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.121 0.879 0.000
T47.4 Other laxatives
0.000 0.880 0.120
E24.8 Other Cushing's syndrome
0.117 0.882 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.117 0.882 0.000
E24.3 Ectopic ACTH syndrome
0.117 0.882 0.000
E24.1 Nelson's syndrome
0.117 0.882 0.000
N50.1 Vascular disorders of male genital organs
0.000 0.883 0.117
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.885 0.115
E27.3 Drug-induced adrenocortical insufficiency
0.114 0.886 0.000
K74 Fibrosis and cirrhosis of liver
0.114 0.886 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.113 0.887 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.113 0.887 0.000
T38.1 Thyroid hormones and substitutes
0.000 0.887 0.113
K73.8 Other chronic hepatitis, not elsewhere classified
0.113 0.887 0.000
T38.9 Other and unspecified hormone antagonists
0.000 0.888 0.111
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.888 0.111
T38.7 Androgens and anabolic congeners
0.000 0.888 0.111
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.888 0.111
T38.5 Other oestrogens and progestogens
0.000 0.888 0.111
T38.4 Oral contraceptives
0.000 0.888 0.111
T38.2 Antithyroid drugs
0.000 0.888 0.111
T38.0 Glucocorticoids and synthetic analogues
0.000 0.888 0.111
E34 Other endocrine disorders
0.111 0.888 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.890 0.109
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.108 0.891 0.000
E11.4 With neurological complications
0.107 0.893 0.000
E24.9 Cushing's syndrome, unspecified
0.107 0.893 0.000
N43.4 Spermatocele
0.000 0.893 0.106
N48.2 Other inflammatory disorders of penis
0.000 0.895 0.105
E25.9 Adrenogenital disorder, unspecified
0.105 0.895 0.000
E25.8 Other adrenogenital disorders
0.105 0.895 0.000
E29 Testicular dysfunction
0.104 0.895 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.896 0.104
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.896 0.104
T46.7 Peripheral vasodilators
0.000 0.896 0.104
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.896 0.104
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.896 0.104
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.896 0.104
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.896 0.104
E27.2 Addisonian crisis
0.103 0.896 0.000
K70.1 Alcoholic hepatitis
0.104 0.896 0.000
E30.9 Disorder of puberty, unspecified
0.103 0.897 0.000
E30.8 Other disorders of puberty
0.103 0.897 0.000
E30.1 Precocious puberty
0.103 0.897 0.000
E30.0 Delayed puberty
0.103 0.897 0.000
E31.9 Polyglandular dysfunction, unspecified
0.103 0.897 0.000
E31.8 Other polyglandular dysfunction
0.103 0.897 0.000
E31.1 Polyglandular hyperfunction
0.103 0.897 0.000
E31.0 Autoimmune polyglandular failure
0.103 0.897 0.000
E32.9 Disease of thymus, unspecified
0.103 0.897 0.000
E32.8 Other diseases of thymus
0.103 0.897 0.000
E32.1 Abscess of thymus
0.103 0.897 0.000
E32.0 Persistent hyperplasia of thymus
0.103 0.897 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.103 0.897 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.103 0.897 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.103 0.897 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.897 0.103
E20.8 Other hypoparathyroidism
0.102 0.897 0.000
E20.1 Pseudohypoparathyroidism
0.102 0.897 0.000
E20.0 Idiopathic hypoparathyroidism
0.102 0.897 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.898 0.102
E20.9 Hypoparathyroidism, unspecified
0.102 0.898 0.000
K70.4 Alcoholic hepatic failure
0.101 0.899 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.899 0.100
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.899 0.100
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.899 0.100
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.899 0.100
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.899 0.100
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.899 0.100
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.899 0.100
T44.0 Anticholinesterase agents
0.000 0.899 0.100
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.902 0.098
K70.0 Alcoholic fatty liver
0.098 0.902 0.000
E28.9 Ovarian dysfunction, unspecified
0.097 0.903 0.000
E28.8 Other ovarian dysfunction
0.097 0.903 0.000
E28.1 Androgen excess
0.097 0.903 0.000
E28.0 Oestrogen excess
0.097 0.903 0.000
T40.2 Other opioids
0.000 0.903 0.097
E28.2 Polycystic ovarian syndrome
0.097 0.903 0.000
E26.9 Hyperaldosteronism, unspecified
0.094 0.905 0.000
E26.8 Other hyperaldosteronism
0.094 0.905 0.000
E26.1 Secondary hyperaldosteronism
0.094 0.905 0.000
N48.4 Impotence of organic origin
0.000 0.905 0.095
K71.0 Toxic liver disease with cholestasis
0.094 0.906 0.000
E11.9 Without complications
0.094 0.906 0.000
E23 Hypofunction and other disorders of pituitary gland
0.093 0.907 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.908 0.092
T40.8 Lysergide [LSD]
0.000 0.908 0.092
T40.7 Cannabis (derivatives)
0.000 0.908 0.092
T40.5 Cocaine
0.000 0.908 0.092
T40.3 Methadone
0.000 0.908 0.092
T40.1 Heroin
0.000 0.908 0.092
T40.0 Opium
0.000 0.908 0.092
K71.9 Toxic liver disease, unspecified
0.091 0.909 0.000
K71.8 Toxic liver disease with other disorders of liver
0.091 0.909 0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.091 0.909 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.091 0.909 0.000
K71.5 Toxic liver disease with chronic active hepatitis
0.091 0.909 0.000
K71.4 Toxic liver disease with chronic lobular hepatitis
0.091 0.909 0.000
K71.3 Toxic liver disease with chronic persistent hepatitis
0.091 0.909 0.000
K71.2 Toxic liver disease with acute hepatitis
0.091 0.909 0.000
K71.1 Toxic liver disease with hepatic necrosis
0.091 0.909 0.000
E04.8 Other specified non-toxic goitre
0.091 0.909 0.000
E22 Hyperfunction of pituitary gland
0.090 0.910 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.090 0.910 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.013 0.910 0.077
E83.8 Other disorders of mineral metabolism
0.013 0.910 0.077
E83.2 Disorders of zinc metabolism
0.013 0.910 0.077

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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