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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130756
log Bayes Factor = 52.5518
Chromosome 6   position 29,017,101  (GRCh37) Explore rs3130756 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.007 0.993
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.021 0.979
E10.2 With renal complications
0.000 0.049 0.951
E10.1 With ketoacidosis
0.000 0.117 0.883
E10.4 With neurological complications
0.000 0.118 0.882
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.185 0.815
E13 Other specified diabetes mellitus
0.000 0.190 0.810
E05.8 Other thyrotoxicosis
0.000 0.192 0.808
E16.1 Other hypoglycaemia
0.000 0.201 0.799
E40-E46 Malnutrition
0.000 0.223 0.777
E10.7 With multiple complications
0.000 0.244 0.756
E10.0 With coma
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E14 Unspecified diabetes mellitus
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E13.9 Without complications
0.000 0.318 0.682
E07 Other disorders of thyroid
0.000 0.327 0.673
E10.6 With other specified complications
0.000 0.337 0.662
E03 Other hypothyroidism
0.000 0.351 0.649
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.356 0.644
E46 Unspecified protein-energy malnutrition
0.000 0.382 0.618
E14.3 With ophthalmic complications
0.000 0.384 0.616
E06 Thyroiditis
0.000 0.388 0.612
E10.5 With peripheral circulatory complications
0.000 0.399 0.601
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.405 0.595
E13.8 With unspecified complications
0.000 0.419 0.581
E13.7 With multiple complications
0.000 0.419 0.581
E13.6 With other specified complications
0.000 0.419 0.581
E13.5 With peripheral circulatory complications
0.000 0.419 0.581
E13.4 With neurological complications
0.000 0.419 0.581
E13.2 With renal complications
0.000 0.419 0.581
E13.1 With ketoacidosis
0.000 0.419 0.581
E13.0 With coma
0.000 0.419 0.581
E14.1 With ketoacidosis
0.000 0.431 0.569
E13.3 With ophthalmic complications
0.000 0.432 0.568
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.443 0.557
E45 Retarded development following protein-energy malnutrition
0.000 0.443 0.557
E43 Unspecified severe protein-energy malnutrition
0.000 0.443 0.557
E42 Marasmic kwashiorkor
0.000 0.443 0.557
E41 Nutritional marasmus
0.000 0.443 0.557
E40 Kwashiorkor
0.000 0.443 0.557
E14.8 With unspecified complications
0.000 0.451 0.549
E14.4 With neurological complications
0.000 0.455 0.545
E07.8 Other specified disorders of thyroid
0.000 0.462 0.537
E10.8 With unspecified complications
0.000 0.465 0.535
E14.6 With other specified complications
0.000 0.467 0.533
E50-E64 Other nutritional deficiencies
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E14.7 With multiple complications
0.000 0.486 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E06.9 Thyroiditis, unspecified
0.000 0.500 0.500
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.505 0.495
E14.5 With peripheral circulatory complications
0.000 0.506 0.494
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.510 0.490
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.514 0.486
E14.0 With coma
0.000 0.516 0.484
E07.1 Dyshormogenetic goitre
0.000 0.518 0.482
E07.0 Hypersecretion of calcitonin
0.000 0.518 0.482
E14.2 Withrenal complications
0.000 0.523 0.477
E03.5 Myxoedema coma
0.000 0.535 0.465
E03.4 Atrophy of thyroid (acquired)
0.000 0.535 0.465
E03.3 Postinfectious hypothyroidism
0.000 0.535 0.465
E06.1 Subacute thyroiditis
0.000 0.536 0.464
E06.4 Drug-induced thyroiditis
0.000 0.561 0.439
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.561 0.439
E06.0 Acute thyroiditis
0.000 0.561 0.439
E03.1 Congenital hypothyroidism without goitre
0.000 0.565 0.435
E03.8 Other specified hypothyroidism
0.000 0.568 0.431
E06.5 Other chronic thyroiditis
0.000 0.573 0.427
E03.9 Hypothyroidism, unspecified
0.000 0.588 0.412
E44.1 Mild protein-energy malnutrition
0.000 0.600 0.399
E44.0 Moderate protein-energy malnutrition
0.000 0.600 0.399
E55 Vitamin D deficiency
0.000 0.621 0.378
E51 Thiamine deficiency
0.000 0.629 0.371
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.630 0.370
E63 Other nutritional deficiencies
0.000 0.630 0.370
E50 Vitamin A deficiency
0.000 0.630 0.370
E60 Dietary zinc deficiency
0.000 0.630 0.370
E59 Dietary selenium deficiency
0.000 0.630 0.370
E52 Niacin deficiency [pellagra]
0.000 0.630 0.370
E54 Ascorbic acid deficiency
0.000 0.636 0.364
E56 Other vitamin deficiencies
0.000 0.638 0.362
E61 Deficiency of other nutrient elements
0.000 0.655 0.345
E07.9 Disorder of thyroid, unspecified
0.000 0.656 0.344
E58 Dietary calcium deficiency
0.000 0.658 0.342
K90 Intestinal malabsorption
0.000 0.674 0.326
E65-E68 Obesity and other hyperalimentation
0.000 0.681 0.319
M45.X9 Ankylosing spondylitis (Site unspecified)
0.310 0.690 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.718 0.282
E55.9 Vitamin D deficiency, unspecified
0.000 0.720 0.280
E53 Deficiency of other B group vitamins
0.000 0.728 0.272
E55.0 Rickets, active
0.000 0.728 0.271
E51.2 Wernicke's encephalopathy
0.000 0.732 0.268
E51.9 Thiamine deficiency, unspecified
0.000 0.733 0.266
E51.8 Other manifestations of thiamine deficiency
0.000 0.733 0.266
E51.1 Beriberi
0.000 0.733 0.266
E50.9 Vitamin A deficiency, unspecified
0.000 0.735 0.265
E50.8 Other manifestations of vitamin A deficiency
0.000 0.735 0.265
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.735 0.265
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.735 0.265
E50.5 Vitamin A deficiency with night blindness
0.000 0.735 0.265
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.735 0.265
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.735 0.265
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.735 0.265
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.735 0.265
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.735 0.265
E63.9 Nutritional deficiency, unspecified
0.000 0.735 0.265
E63.8 Other specified nutritional deficiencies
0.000 0.735 0.265
E63.1 Imbalance of constituents of food intake
0.000 0.735 0.265
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.735 0.265
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.735 0.265
E64.8 Sequelae of other nutritional deficiencies
0.000 0.735 0.265
E64.3 Sequelae of rickets
0.000 0.735 0.265
E64.2 Sequelae of vitamin C deficiency
0.000 0.735 0.265
E64.1 Sequelae of vitamin A deficiency
0.000 0.735 0.265
E64.0 Sequelae of protein-energy malnutrition
0.000 0.735 0.265
E56.9 Vitamin deficiency, unspecified
0.000 0.740 0.260
E56.8 Deficiency of other vitamins
0.000 0.740 0.260
E56.0 Deficiency of vitamin E
0.000 0.740 0.260
E11.6 With other specified complications
0.000 0.742 0.258
E61.1 Iron deficiency
0.000 0.746 0.254
E56.1 Deficiency of vitamin K
0.000 0.747 0.252
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.751 0.249
E61.9 Deficiency of nutrient element, unspecified
0.000 0.752 0.247
E61.8 Deficiency of other specified nutrient elements
0.000 0.752 0.247
E61.7 Deficiency of multiple nutrient elements
0.000 0.752 0.247
E61.6 Vanadium deficiency
0.000 0.752 0.247
E61.5 Molybdenum deficiency
0.000 0.752 0.247
E61.4 Chromium deficiency
0.000 0.752 0.247
E61.3 Manganese deficiency
0.000 0.752 0.247
E61.0 Copper deficiency
0.000 0.752 0.247
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.241 0.759 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.766 0.234
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.766 0.234
K90.1 Tropical sprue
0.000 0.766 0.234
E67 Other hyperalimentation
0.000 0.771 0.229
E68 Sequelae of hyperalimentation
0.000 0.771 0.229
E11.2 With renal complications
0.000 0.772 0.228
E11.1 With ketoacidosis
0.000 0.772 0.228
K90.8 Other intestinal malabsorption
0.000 0.780 0.220
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.784 0.216
E61.2 Magnesium deficiency
0.000 0.786 0.214
E53.9 Vitamin B deficiency, unspecified
0.000 0.788 0.212
E11.0 With coma
0.000 0.789 0.211
E11.7 With multiple complications
0.000 0.798 0.202
E53.1 Pyridoxine deficiency
0.000 0.805 0.195
E53.0 Riboflavin deficiency
0.000 0.805 0.195
K90.9 Intestinal malabsorption, unspecified
0.000 0.826 0.174
E65 Localised adiposity
0.000 0.828 0.172
E11.8 With unspecified complications
0.000 0.830 0.170
E20-E35 Disorders of other endocrine glands
0.000 0.831 0.169
E67.8 Other specified hyperalimentation
0.000 0.835 0.164
E67.3 Hypervitaminosis D
0.000 0.835 0.164
E67.2 Megavitamin-B6 syndrome
0.000 0.835 0.164
E67.1 Hypercarotenaemia
0.000 0.835 0.164
E67.0 Hypervitaminosis A
0.000 0.835 0.164
E24 Cushing's syndrome
0.000 0.844 0.156
E83 Disorders of mineral metabolism
0.134 0.848 0.018
M45 Ankylosing spondylitis
0.149 0.851 0.000
E06.3 Autoimmune thyroiditis
0.001 0.852 0.148
C15-C26 Malignant neoplasms of digestive organs
0.000 0.852 0.148
C20 Malignant neoplasm of rectum
0.000 0.853 0.147
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.853 0.147
C15 Malignant neoplasm of oesophagus
0.000 0.859 0.141
E21.3 Hyperparathyroidism, unspecified
0.000 0.861 0.139
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.861 0.139
E24.9 Cushing's syndrome, unspecified
0.000 0.866 0.134
E24.0 Pituitary-dependent Cushing's disease
0.000 0.868 0.132
E11.3 With ophthalmic complications
0.000 0.869 0.131
C15.5 Lower third of oesophagus
0.000 0.869 0.131
C25 Malignant neoplasm of pancreas
0.000 0.874 0.126
E24.2 Drug-induced Cushing's syndrome
0.000 0.876 0.124
S02.4 Fracture of malar and maxillary bones
0.000 0.878 0.122
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.879 0.121
E32 Diseases of thymus
0.000 0.879 0.121
E30 Disorders of puberty, not elsewhere classified
0.000 0.879 0.121
C15.4 Middle third of oesophagus
0.000 0.879 0.121
E20 Hypoparathyroidism
0.000 0.880 0.120
E25 Adrenogenital disorders
0.000 0.882 0.118
M45.X2 Ankylosing spondylitis (Cervical region)
0.118 0.882 0.000
E31 Polyglandular dysfunction
0.000 0.884 0.116
E83.3 Disorders of phosphorus metabolism
0.110 0.885 0.005
M45.X6 Ankylosing spondylitis (Lumbar region)
0.114 0.886 0.000
C17 Malignant neoplasm of small intestine
0.000 0.886 0.113
E24.8 Other Cushing's syndrome
0.000 0.888 0.112
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.888 0.112
E24.3 Ectopic ACTH syndrome
0.000 0.888 0.112
E24.1 Nelson's syndrome
0.000 0.888 0.112
E21.4 Other specified disorders of parathyroid gland
0.000 0.888 0.112
S02 Fracture of skull and facial bones
0.000 0.889 0.111
E14.9 Without complications
0.000 0.889 0.111
E28 Ovarian dysfunction
0.000 0.890 0.109
E83.8 Other disorders of mineral metabolism
0.096 0.891 0.013
E83.2 Disorders of zinc metabolism
0.096 0.891 0.013
E83.0 Disorders of copper metabolism
0.096 0.891 0.013
E11.5 With peripheral circulatory complications
0.000 0.891 0.109
C17.0 Duodenum
0.000 0.892 0.108
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.892 0.108
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.892 0.108
E83.9 Disorder of mineral metabolism, unspecified
0.095 0.892 0.013
C15.9 Oesophagus, unspecified
0.000 0.892 0.108
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.107 0.893 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.107 0.893 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.107 0.893 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.107 0.893 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.107 0.893 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.107 0.893 0.000
E21.2 Other hyperparathyroidism
0.000 0.893 0.107
C25.2 Tail of pancreas
0.000 0.896 0.104
C25.3 Pancreatic duct
0.000 0.897 0.103
C25.1 Body of pancreas
0.000 0.897 0.103
C15.0 Cervical part of oesophagus
0.000 0.898 0.102
E29 Testicular dysfunction
0.000 0.898 0.102
C15.8 Overlapping lesion of oesophagus
0.000 0.899 0.101
C15.2 Abdominal part of oesophagus
0.000 0.899 0.101
C15.1 Thoracic part of oesophagus
0.000 0.901 0.099
S02.8 Fractures of other skull and facial bones
0.000 0.903 0.097
S02.0 Fracture of vault of skull
0.000 0.904 0.096
C25.8 Overlapping lesion of pancreas
0.000 0.904 0.095
C24.0 Extrahepatic bile duct
0.000 0.904 0.095
C25.4 Endocrine pancreas
0.000 0.905 0.095
S02.3 Fracture of orbital floor
0.000 0.905 0.095
C15.3 Upper third of oesophagus
0.000 0.907 0.093
C25.9 Pancreas, unspecified
0.000 0.907 0.093
S02.6 Fracture of mandible
0.000 0.909 0.091
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.090 0.910 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.912 0.088
S02.7 Multiple fractures involving skull and facial bones
0.000 0.912 0.087
E30.9 Disorder of puberty, unspecified
0.000 0.913 0.087
E30.8 Other disorders of puberty
0.000 0.913 0.087
E30.1 Precocious puberty
0.000 0.913 0.087
E30.0 Delayed puberty
0.000 0.913 0.087
E32.9 Disease of thymus, unspecified
0.000 0.913 0.087
E32.8 Other diseases of thymus
0.000 0.913 0.087
E32.1 Abscess of thymus
0.000 0.913 0.087
E32.0 Persistent hyperplasia of thymus
0.000 0.913 0.087
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.913 0.087
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.913 0.087
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.913 0.087
E34 Other endocrine disorders
0.000 0.913 0.087
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.913 0.087
E20.8 Other hypoparathyroidism
0.000 0.914 0.086
E20.1 Pseudohypoparathyroidism
0.000 0.914 0.086
E20.0 Idiopathic hypoparathyroidism
0.000 0.914 0.086
S02.00 Fracture of vault of skull (closed)
0.000 0.915 0.085
E20.9 Hypoparathyroidism, unspecified
0.000 0.915 0.085
E25.9 Adrenogenital disorder, unspecified
0.000 0.915 0.085
E25.8 Other adrenogenital disorders
0.000 0.915 0.085
E31.9 Polyglandular dysfunction, unspecified
0.000 0.916 0.083
E31.8 Other polyglandular dysfunction
0.000 0.916 0.083
E31.1 Polyglandular hyperfunction
0.000 0.916 0.083
E26 Hyperaldosteronism
0.000 0.916 0.083
C25.7 Other parts of pancreas
0.000 0.916 0.083
R31 Unspecified haematuria
0.083 0.917 0.000
C21 Malignant neoplasm of anus and anal canal
0.000 0.917 0.083
S02.30 Fracture of orbital floor (closed)
0.000 0.917 0.083
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.918 0.082
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.918 0.082
C17.8 Overlapping lesion of small intestine
0.000 0.918 0.081
C17.3 Meckel's diverticulum
0.000 0.918 0.081
S02.5 Fracture of tooth
0.000 0.919 0.081
E21.0 Primary hyperparathyroidism
0.000 0.921 0.079
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.921 0.079
E70-E90 Metabolic disorders
0.001 0.921 0.078
E28.9 Ovarian dysfunction, unspecified
0.000 0.921 0.079
E28.8 Other ovarian dysfunction
0.000 0.921 0.079
E28.1 Androgen excess
0.000 0.921 0.079
E28.0 Oestrogen excess
0.000 0.921 0.079
E31.0 Autoimmune polyglandular failure
0.000 0.921 0.078
C17.1 Jejunum
0.000 0.922 0.078
C24.8 Overlapping lesion of biliary tract
0.000 0.922 0.077
S02.2 Fracture of nasal bones
0.000 0.923 0.077
S02.60 Fracture of mandible (closed)
0.000 0.924 0.076
C24.9 Biliary tract, unspecified
0.000 0.925 0.075
C23 Malignant neoplasm of gallbladder
0.000 0.925 0.075
E29.9 Testicular dysfunction, unspecified
0.000 0.925 0.075
E28.3 Primary ovarian failure
0.000 0.925 0.075
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.925 0.074
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.926 0.074
E22 Hyperfunction of pituitary gland
0.000 0.926 0.074
E29.8 Other testicular dysfunction
0.000 0.927 0.073
E29.0 Testicular hyperfunction
0.000 0.927 0.073
E78.2 Mixed hyperlipidaemia
0.000 0.928 0.072
E28.2 Polycystic ovarian syndrome
0.000 0.928 0.072
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.930 0.070
S02.81 Fractures of other skull and facial bones (open)
0.000 0.930 0.070
E78.5 Hyperlipidaemia, unspecified
0.000 0.930 0.070
S02.01 Fracture of vault of skull (open)
0.000 0.931 0.069
S02.31 Fracture of orbital floor (open)
0.000 0.932 0.068
S02.1 Fracture of base of skull
0.000 0.935 0.065
S02.61 Fracture of mandible (open)
0.000 0.935 0.065
E34.3 Short stature, not elsewhere classified
0.000 0.936 0.064
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.936 0.064
C18.9 Colon, unspecified
0.000 0.937 0.063
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.937 0.063
E78.1 Pure hyperglyceridaemia
0.000 0.937 0.063
C18 Malignant neoplasm of colon
0.000 0.937 0.063
E34.5 Androgen resistance syndrome
0.000 0.937 0.062
E34.4 Constitutional tall stature
0.000 0.937 0.062
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.937 0.062
E34.1 Other hypersecretion of intestinal hormones
0.000 0.937 0.062
S02.21 Fracture of nasal bones (open)
0.000 0.938 0.062
E74 Other disorders of carbohydrate metabolism
0.001 0.940 0.059
E26.8 Other hyperaldosteronism
0.000 0.940 0.060
E26.1 Secondary hyperaldosteronism
0.000 0.940 0.060
C21.2 Cloacogenic zone
0.000 0.940 0.060
S02.50 Fracture of tooth (closed)
0.000 0.940 0.059
E73 Lactose intolerance
0.001 0.941 0.059
E78.6 Lipoprotein deficiency
0.000 0.941 0.059
C18.1 Appendix
0.000 0.941 0.059
S02.51 Fracture of tooth (open)
0.000 0.941 0.058
C17.9 Small intestine, unspecified
0.000 0.942 0.058
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.942 0.057
E88 Other metabolic disorders
0.001 0.942 0.057
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.942 0.057
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.943 0.057
E78.3 Hyperchylomicronaemia
0.000 0.943 0.057
E85 Amyloidosis
0.001 0.943 0.056
E77 Disorders of glycoprotein metabolism
0.001 0.943 0.056
E76 Disorders of glycosaminoglycan metabolism
0.001 0.943 0.056
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.943 0.056
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.943 0.056
E26.9 Hyperaldosteronism, unspecified
0.000 0.944 0.056
E72 Other disorders of amino-acid metabolism
0.001 0.944 0.055
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.944 0.056
E34.8 Other specified endocrine disorders
0.000 0.944 0.055
E22.1 Hyperprolactinaemia
0.000 0.945 0.055
E70 Disorders of aromatic amino-acid metabolism
0.001 0.946 0.053
E83.4 Disorders of magnesium metabolism
0.046 0.946 0.008
E34.9 Endocrine disorder, unspecified
0.000 0.946 0.053
E11.4 With neurological complications
0.000 0.947 0.053
C26.8 Overlapping lesion of digestive system
0.000 0.947 0.053
C26.1 Spleen
0.000 0.947 0.053
E22.8 Other hyperfunction of pituitary gland
0.000 0.947 0.053
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.947 0.053
E79 Disorders of purine and pyrimidine metabolism
0.001 0.948 0.051
E34.0 Carcinoid syndrome
0.000 0.948 0.052
C25.0 Head of pancreas
0.000 0.949 0.051
E29.1 Testicular hypofunction
0.000 0.949 0.051
E84 Cystic fibrosis
0.001 0.949 0.049
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.950 0.050
C21.0 Anus, unspecified
0.000 0.950 0.050
C17.2 Ileum
0.000 0.951 0.049
Z71.8 Other specified counselling
0.048 0.952 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.952 0.048
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.953 0.046
E85.4 Organ-limited amyloidosis
0.000 0.954 0.046
E53.8 Deficiency of other specified B group vitamins
0.000 0.954 0.046
S02.11 Fracture of base of skull (open)
0.000 0.954 0.046
E78.4 Other hyperlipidaemia
0.000 0.955 0.045
E73.9 Lactose intolerance, unspecified
0.000 0.955 0.045
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.955 0.045
C18.8 Overlapping lesion of colon
0.000 0.956 0.044
E04 Other non-toxic goitre
0.002 0.956 0.042
C21.1 Anal canal
0.000 0.956 0.044
E75.5 Other lipid storage disorders
0.001 0.956 0.043
Z72.0 Tobacco use
0.044 0.956 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.956 0.043
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.956 0.043
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.956 0.043
E74.2 Disorders of galactose metabolism
0.001 0.956 0.043
E74.1 Disorders of fructose metabolism
0.001 0.956 0.043
E74.0 Glycogen storage disease
0.001 0.956 0.043
C24.1 Ampulla of Vater
0.001 0.957 0.043
E23 Hypofunction and other disorders of pituitary gland
0.000 0.957 0.043
E73.8 Other lactose intolerance
0.001 0.957 0.042
E73.1 Secondary lactase deficiency
0.001 0.957 0.042
E73.0 Congenital lactase deficiency
0.001 0.957 0.042
C26.0 Intestinal tract, part unspecified
0.000 0.957 0.042
E85.3 Secondary systemic amyloidosis
0.001 0.958 0.042
E88.2 Lipomatosis, not elsewhere classified
0.000 0.958 0.042
E75.6 Lipid storage disorder, unspecified
0.001 0.958 0.041
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.958 0.041
E75.3 Sphingolipidosis, unspecified
0.001 0.958 0.041
E75.1 Other gangliosidosis
0.001 0.958 0.041
E75.0 GM2 gangliosidosis
0.001 0.958 0.041
C22.7 Other specified carcinomas of liver
0.000 0.958 0.041
C22.4 Other sarcomas of liver
0.000 0.958 0.041
C22.3 Angiosarcoma of liver
0.000 0.958 0.041
C22.2 Hepatoblastoma
0.000 0.958 0.041
E75.2 Other sphingolipidosis
0.001 0.959 0.040
E71.3 Disorders of fatty-acid metabolism
0.001 0.959 0.040
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.959 0.040
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.959 0.040
E71.0 Maple-syrup-urine disease
0.001 0.959 0.040
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.959 0.040
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.959 0.040
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.959 0.040
E76.2 Other mucopolysaccharidoses
0.001 0.959 0.040
E76.1 Mucopolysaccharidosis, type II
0.001 0.959 0.040
E76.0 Mucopolysaccharidosis, type I
0.001 0.959 0.040
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.959 0.040
E77.8 Other disorders of glycoprotein metabolism
0.001 0.959 0.040
E77.1 Defects in glycoprotein degradation
0.001 0.959 0.040
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.959 0.040
E85.8 Other amyloidosis
0.001 0.959 0.040
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.959 0.040
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.959 0.040
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.959 0.040
C22.9 Liver, unspecified
0.000 0.959 0.041
S02.20 Fracture of nasal bones (closed)
0.000 0.959 0.041
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.959 0.040
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.959 0.040
E72.5 Disorders of glycine metabolism
0.001 0.959 0.040
E72.4 Disorders of ornithine metabolism
0.001 0.959 0.040
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.959 0.040
E72.2 Disorders of urea cycle metabolism
0.001 0.959 0.040
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.959 0.040
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.960 0.040
E72.0 Disorders of amino-acid transport
0.001 0.960 0.039
C18.4 Transverse colon
0.000 0.961 0.039
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.961 0.038
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.961 0.038
E70.2 Disorders of tyrosine metabolism
0.001 0.961 0.038
E70.1 Other hyperphenylalaninaemias
0.001 0.961 0.038
E70.0 Classical phenylketonuria
0.001 0.961 0.038
C26.9 Ill-defined sites within the digestive system
0.000 0.961 0.039
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.961 0.039
S00-S09 Injuries to the head
0.000 0.961 0.039
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.962 0.037
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.962 0.037
E79.1 Lesch-Nyhan syndrome
0.001 0.962 0.037
E70.3 Albinism
0.001 0.963 0.036
E84.8 Cystic fibrosis with other manifestations
0.001 0.963 0.036
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.963 0.036
E88.8 Other specified metabolic disorders
0.001 0.964 0.036
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.964 0.035
S05 Injury of eye and orbit
0.000 0.964 0.036
E88.3 Tumour lysis syndrome
0.001 0.965 0.034
C18.7 Sigmoid colon
0.000 0.965 0.035
E22.0 Acromegaly and pituitary gigantism
0.000 0.965 0.034
C18.6 Descending colon
0.000 0.966 0.034
S02.10 Fracture of base of skull (closed)
0.000 0.966 0.034
S00 Superficial injury of head
0.000 0.966 0.034
E11.9 Without complications
0.000 0.966 0.034
C22.1 Intrahepatic bile duct carcinoma
0.000 0.967 0.033
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.967 0.033
E23.7 Disorder of pituitary gland, unspecified
0.000 0.967 0.033
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.967 0.032
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.033 0.967 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.967 0.032
S00.0 Superficial injury of scalp
0.000 0.968 0.032
E04.8 Other specified non-toxic goitre
0.002 0.968 0.030
E85.9 Amyloidosis, unspecified
0.001 0.969 0.031
E26.0 Primary hyperaldosteronism
0.001 0.969 0.031
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.969 0.031
E23.1 Drug-induced hypopituitarism
0.000 0.969 0.031
S05.8 Other injuries of eye and orbit
0.000 0.969 0.031
E84.9 Cystic fibrosis, unspecified
0.001 0.969 0.030
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.969 0.031
I83 Varicose veins of lower extremities
0.031 0.969 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.970 0.030
S00.4 Superficial injury of ear
0.000 0.971 0.029
E27 Other disorders of adrenal gland
0.000 0.971 0.029
S07 Crushing injury of head
0.000 0.972 0.028
S04 Injury of cranial nerves
0.000 0.972 0.028
S08 Traumatic amputation of part of head
0.000 0.972 0.027
C18.3 Hepatic flexure
0.000 0.973 0.027
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.973 0.027
S00.1 Contusion of eyelid and periocular area
0.000 0.973 0.027
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.973 0.027
E78.8 Other disorders of lipoprotein metabolism
0.000 0.974 0.026
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.974 0.026

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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