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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130766
log Bayes Factor = 55.1646
Chromosome 6   position 29,086,829  (GRCh37) Explore rs3130766 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.008 0.992
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.033 0.967
E10.2 With renal complications
0.000 0.044 0.956
E10.4 With neurological complications
0.000 0.115 0.885
E10.1 With ketoacidosis
0.000 0.121 0.879
E05.8 Other thyrotoxicosis
0.000 0.171 0.829
E16.1 Other hypoglycaemia
0.000 0.204 0.796
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.214 0.786
E13 Other specified diabetes mellitus
0.000 0.226 0.774
E10.7 With multiple complications
0.000 0.245 0.755
E40-E46 Malnutrition
0.000 0.255 0.744
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E10.0 With coma
0.000 0.287 0.713
E14 Unspecified diabetes mellitus
0.000 0.319 0.681
E10.6 With other specified complications
0.000 0.342 0.658
E10.5 With peripheral circulatory complications
0.000 0.357 0.643
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.357 0.643
E07 Other disorders of thyroid
0.000 0.365 0.635
E03 Other hypothyroidism
0.000 0.369 0.631
E13.9 Without complications
0.000 0.377 0.623
E06 Thyroiditis
0.000 0.385 0.615
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.411 0.588
E14.3 With ophthalmic complications
0.000 0.419 0.581
E46 Unspecified protein-energy malnutrition
0.000 0.437 0.562
E10.8 With unspecified complications
0.000 0.438 0.561
E13.8 With unspecified complications
0.000 0.445 0.555
E13.7 With multiple complications
0.000 0.445 0.555
E13.6 With other specified complications
0.000 0.445 0.555
E13.5 With peripheral circulatory complications
0.000 0.445 0.555
E13.4 With neurological complications
0.000 0.445 0.555
E13.2 With renal complications
0.000 0.445 0.555
E13.1 With ketoacidosis
0.000 0.445 0.555
E13.0 With coma
0.000 0.445 0.555
E13.3 With ophthalmic complications
0.000 0.458 0.542
E14.1 With ketoacidosis
0.000 0.460 0.540
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.466 0.534
E45 Retarded development following protein-energy malnutrition
0.000 0.466 0.534
E43 Unspecified severe protein-energy malnutrition
0.000 0.466 0.534
E42 Marasmic kwashiorkor
0.000 0.466 0.534
E41 Nutritional marasmus
0.000 0.466 0.534
E40 Kwashiorkor
0.000 0.466 0.534
E14.8 With unspecified complications
0.000 0.479 0.520
E14.4 With neurological complications
0.000 0.484 0.516
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E06.9 Thyroiditis, unspecified
0.000 0.488 0.512
E14.6 With other specified complications
0.000 0.494 0.506
E07.8 Other specified disorders of thyroid
0.000 0.497 0.503
E14.7 With multiple complications
0.000 0.512 0.488
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.524 0.476
E14.5 With peripheral circulatory complications
0.000 0.532 0.468
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.534 0.466
E14.0 With coma
0.000 0.540 0.460
K90 Intestinal malabsorption
0.000 0.542 0.458
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.543 0.457
E07.1 Dyshormogenetic goitre
0.000 0.545 0.455
E07.0 Hypersecretion of calcitonin
0.000 0.545 0.455
E03.5 Myxoedema coma
0.000 0.547 0.453
E03.4 Atrophy of thyroid (acquired)
0.000 0.547 0.453
E03.3 Postinfectious hypothyroidism
0.000 0.547 0.453
E14.2 Withrenal complications
0.000 0.548 0.452
E06.1 Subacute thyroiditis
0.000 0.552 0.448
E06.4 Drug-induced thyroiditis
0.000 0.559 0.441
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.559 0.441
E06.0 Acute thyroiditis
0.000 0.559 0.441
E03.1 Congenital hypothyroidism without goitre
0.000 0.560 0.440
E06.5 Other chronic thyroiditis
0.000 0.572 0.427
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.414 0.586 0.000
E03.8 Other specified hypothyroidism
0.000 0.587 0.413
E44.1 Mild protein-energy malnutrition
0.000 0.617 0.383
E44.0 Moderate protein-energy malnutrition
0.000 0.617 0.383
E03.9 Hypothyroidism, unspecified
0.000 0.618 0.382
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.623 0.377
E65-E68 Obesity and other hyperalimentation
0.000 0.639 0.361
E50-E64 Other nutritional deficiencies
0.000 0.648 0.352
K90.3 Pancreatic steatorrhoea
0.000 0.671 0.329
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.671 0.329
K90.1 Tropical sprue
0.000 0.671 0.329
K90.8 Other intestinal malabsorption
0.000 0.679 0.321
K90.9 Intestinal malabsorption, unspecified
0.000 0.718 0.282
E07.9 Disorder of thyroid, unspecified
0.000 0.718 0.282
E67 Other hyperalimentation
0.000 0.741 0.259
E68 Sequelae of hyperalimentation
0.000 0.741 0.259
E51 Thiamine deficiency
0.000 0.747 0.253
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.747 0.253
E50 Vitamin A deficiency
0.000 0.747 0.253
E60 Dietary zinc deficiency
0.000 0.747 0.253
E59 Dietary selenium deficiency
0.000 0.747 0.253
E52 Niacin deficiency [pellagra]
0.000 0.747 0.253
E54 Ascorbic acid deficiency
0.000 0.752 0.248
E56 Other vitamin deficiencies
0.000 0.760 0.240
E20-E35 Disorders of other endocrine glands
0.000 0.760 0.240
E55 Vitamin D deficiency
0.000 0.764 0.236
E58 Dietary calcium deficiency
0.000 0.767 0.233
E63 Other nutritional deficiencies
0.000 0.771 0.229
E24 Cushing's syndrome
0.000 0.778 0.222
E65 Localised adiposity
0.000 0.778 0.221
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.781 0.219
E61 Deficiency of other nutrient elements
0.000 0.786 0.214
E21.3 Hyperparathyroidism, unspecified
0.000 0.790 0.210
E24.9 Cushing's syndrome, unspecified
0.000 0.807 0.193
E53 Deficiency of other B group vitamins
0.000 0.813 0.187
E24.0 Pituitary-dependent Cushing's disease
0.000 0.813 0.187
E67.8 Other specified hyperalimentation
0.000 0.814 0.186
E67.3 Hypervitaminosis D
0.000 0.814 0.186
E67.2 Megavitamin-B6 syndrome
0.000 0.814 0.186
E67.1 Hypercarotenaemia
0.000 0.814 0.186
E67.0 Hypervitaminosis A
0.000 0.814 0.186
M45.X9 Ankylosing spondylitis (Site unspecified)
0.184 0.816 0.000
E51.2 Wernicke's encephalopathy
0.000 0.818 0.182
E51.9 Thiamine deficiency, unspecified
0.000 0.818 0.182
E51.8 Other manifestations of thiamine deficiency
0.000 0.818 0.182
E51.1 Beriberi
0.000 0.818 0.182
E50.9 Vitamin A deficiency, unspecified
0.000 0.819 0.181
E50.8 Other manifestations of vitamin A deficiency
0.000 0.819 0.181
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.819 0.181
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.819 0.181
E50.5 Vitamin A deficiency with night blindness
0.000 0.819 0.181
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.819 0.181
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.819 0.181
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.819 0.181
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.819 0.181
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.819 0.181
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.819 0.181
E64.8 Sequelae of other nutritional deficiencies
0.000 0.819 0.181
E64.3 Sequelae of rickets
0.000 0.819 0.181
E64.2 Sequelae of vitamin C deficiency
0.000 0.819 0.181
E64.1 Sequelae of vitamin A deficiency
0.000 0.819 0.181
E64.0 Sequelae of protein-energy malnutrition
0.000 0.819 0.181
E24.2 Drug-induced Cushing's syndrome
0.000 0.824 0.176
R31 Unspecified haematuria
0.176 0.824 0.000
E20 Hypoparathyroidism
0.000 0.826 0.174
E56.9 Vitamin deficiency, unspecified
0.000 0.827 0.172
E56.8 Deficiency of other vitamins
0.000 0.827 0.172
E56.0 Deficiency of vitamin E
0.000 0.827 0.172
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.828 0.172
E32 Diseases of thymus
0.000 0.828 0.172
E30 Disorders of puberty, not elsewhere classified
0.000 0.828 0.172
E21.4 Other specified disorders of parathyroid gland
0.000 0.828 0.172
E55.0 Rickets, active
0.000 0.830 0.170
E25 Adrenogenital disorders
0.000 0.832 0.168
E06.3 Autoimmune thyroiditis
0.000 0.833 0.167
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.835 0.165
E31 Polyglandular dysfunction
0.000 0.835 0.165
E63.8 Other specified nutritional deficiencies
0.000 0.835 0.164
E63.1 Imbalance of constituents of food intake
0.000 0.835 0.164
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.835 0.164
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.838 0.162
E56.1 Deficiency of vitamin K
0.000 0.840 0.160
E24.8 Other Cushing's syndrome
0.000 0.840 0.160
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.840 0.160
E24.3 Ectopic ACTH syndrome
0.000 0.840 0.160
E24.1 Nelson's syndrome
0.000 0.840 0.160
E21.2 Other hyperparathyroidism
0.000 0.841 0.159
E61.9 Deficiency of nutrient element, unspecified
0.000 0.847 0.153
E61.8 Deficiency of other specified nutrient elements
0.000 0.847 0.153
E61.7 Deficiency of multiple nutrient elements
0.000 0.847 0.153
E61.6 Vanadium deficiency
0.000 0.847 0.153
E61.5 Molybdenum deficiency
0.000 0.847 0.153
E61.4 Chromium deficiency
0.000 0.847 0.153
E61.3 Manganese deficiency
0.000 0.847 0.153
E61.0 Copper deficiency
0.000 0.847 0.153
E55.9 Vitamin D deficiency, unspecified
0.000 0.847 0.153
E28 Ovarian dysfunction
0.000 0.847 0.153
E53.9 Vitamin B deficiency, unspecified
0.000 0.854 0.146
E29 Testicular dysfunction
0.000 0.858 0.142
E63.9 Nutritional deficiency, unspecified
0.000 0.859 0.141
E61.1 Iron deficiency
0.000 0.859 0.141
E11 Non-insulin-dependent diabetes mellitus
0.000 0.860 0.140
E83 Disorders of mineral metabolism
0.132 0.860 0.008
E53.1 Pyridoxine deficiency
0.000 0.866 0.134
E53.0 Riboflavin deficiency
0.000 0.866 0.134
E34 Other endocrine disorders
0.000 0.866 0.134
E61.2 Magnesium deficiency
0.000 0.868 0.131
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.870 0.130
E11.6 With other specified complications
0.000 0.872 0.128
E20.9 Hypoparathyroidism, unspecified
0.000 0.873 0.127
E20.8 Other hypoparathyroidism
0.000 0.875 0.125
E20.1 Pseudohypoparathyroidism
0.000 0.875 0.125
E20.0 Idiopathic hypoparathyroidism
0.000 0.875 0.125
E30.9 Disorder of puberty, unspecified
0.000 0.876 0.123
E30.8 Other disorders of puberty
0.000 0.876 0.123
E30.1 Precocious puberty
0.000 0.876 0.123
E30.0 Delayed puberty
0.000 0.876 0.123
E32.9 Disease of thymus, unspecified
0.000 0.876 0.123
E32.8 Other diseases of thymus
0.000 0.876 0.123
E32.1 Abscess of thymus
0.000 0.876 0.123
E32.0 Persistent hyperplasia of thymus
0.000 0.876 0.123
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.876 0.123
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.876 0.123
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.876 0.123
E25.9 Adrenogenital disorder, unspecified
0.000 0.880 0.120
E25.8 Other adrenogenital disorders
0.000 0.880 0.120
E31.9 Polyglandular dysfunction, unspecified
0.000 0.882 0.118
E31.8 Other polyglandular dysfunction
0.000 0.882 0.118
E31.1 Polyglandular hyperfunction
0.000 0.882 0.118
E21.0 Primary hyperparathyroidism
0.000 0.883 0.117
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.884 0.116
E26 Hyperaldosteronism
0.000 0.886 0.114
E83.3 Disorders of phosphorus metabolism
0.110 0.888 0.002
E31.0 Autoimmune polyglandular failure
0.000 0.889 0.111
E28.9 Ovarian dysfunction, unspecified
0.000 0.890 0.110
E28.8 Other ovarian dysfunction
0.000 0.890 0.110
E28.1 Androgen excess
0.000 0.890 0.110
E28.0 Oestrogen excess
0.000 0.890 0.110
E28.2 Polycystic ovarian syndrome
0.000 0.893 0.107
E11.1 With ketoacidosis
0.000 0.895 0.105
E11.2 With renal complications
0.000 0.895 0.105
E11.0 With coma
0.000 0.896 0.104
E29.9 Testicular dysfunction, unspecified
0.000 0.898 0.102
E29.8 Other testicular dysfunction
0.000 0.898 0.102
E29.0 Testicular hyperfunction
0.000 0.898 0.102
E11.7 With multiple complications
0.000 0.899 0.101
E83.8 Other disorders of mineral metabolism
0.094 0.900 0.006
E83.2 Disorders of zinc metabolism
0.094 0.900 0.006
E83.0 Disorders of copper metabolism
0.094 0.900 0.006
E83.9 Disorder of mineral metabolism, unspecified
0.094 0.901 0.006
E34.3 Short stature, not elsewhere classified
0.000 0.902 0.098
E34.5 Androgen resistance syndrome
0.000 0.904 0.096
E34.4 Constitutional tall stature
0.000 0.904 0.096
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.904 0.096
E34.1 Other hypersecretion of intestinal hormones
0.000 0.904 0.096
E28.3 Primary ovarian failure
0.000 0.906 0.094
E22 Hyperfunction of pituitary gland
0.000 0.909 0.091
C20 Malignant neoplasm of rectum
0.000 0.911 0.089
C15-C26 Malignant neoplasms of digestive organs
0.000 0.911 0.089
E34.9 Endocrine disorder, unspecified
0.000 0.911 0.089
M45 Ankylosing spondylitis
0.087 0.913 0.000
E34.8 Other specified endocrine disorders
0.000 0.916 0.084
E11.8 With unspecified complications
0.000 0.916 0.083
E34.0 Carcinoid syndrome
0.000 0.917 0.082
C15 Malignant neoplasm of oesophagus
0.000 0.918 0.082
E26.8 Other hyperaldosteronism
0.000 0.918 0.082
E26.1 Secondary hyperaldosteronism
0.000 0.918 0.082
I83 Varicose veins of lower extremities
0.081 0.919 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.920 0.080
C25 Malignant neoplasm of pancreas
0.000 0.922 0.078
E26.9 Hyperaldosteronism, unspecified
0.001 0.927 0.073
C15.5 Lower third of oesophagus
0.000 0.927 0.073
E29.1 Testicular hypofunction
0.000 0.928 0.072
E14.9 Without complications
0.000 0.929 0.071
C15.4 Middle third of oesophagus
0.000 0.930 0.070
M45.X2 Ankylosing spondylitis (Cervical region)
0.070 0.930 0.000
S02.4 Fracture of malar and maxillary bones
0.000 0.932 0.068
C17 Malignant neoplasm of small intestine
0.000 0.933 0.067
M45.X6 Ankylosing spondylitis (Lumbar region)
0.067 0.933 0.000
C25.1 Body of pancreas
0.000 0.933 0.067
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.934 0.066
C25.3 Pancreatic duct
0.000 0.934 0.066
E22.8 Other hyperfunction of pituitary gland
0.000 0.935 0.065
C15.9 Oesophagus, unspecified
0.000 0.935 0.065
E23 Hypofunction and other disorders of pituitary gland
0.000 0.935 0.064
C25.2 Tail of pancreas
0.000 0.936 0.064
C17.0 Duodenum
0.000 0.937 0.063
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.063 0.937 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.063 0.937 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.063 0.937 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.063 0.937 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.063 0.937 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.063 0.937 0.000
C15.0 Cervical part of oesophagus
0.000 0.938 0.062
E22.1 Hyperprolactinaemia
0.000 0.938 0.062
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.938 0.061
C25.4 Endocrine pancreas
0.000 0.939 0.061
S02 Fracture of skull and facial bones
0.000 0.940 0.060
C24.0 Extrahepatic bile duct
0.000 0.940 0.059
C15.8 Overlapping lesion of oesophagus
0.000 0.941 0.059
C15.2 Abdominal part of oesophagus
0.000 0.941 0.059
C25.8 Overlapping lesion of pancreas
0.000 0.941 0.059
Z71.8 Other specified counselling
0.059 0.941 0.000
C15.1 Thoracic part of oesophagus
0.000 0.942 0.058
I83.0 Varicose veins of lower extremities with ulcer
0.055 0.944 0.000
C25.9 Pancreas, unspecified
0.000 0.945 0.055
E11.3 With ophthalmic complications
0.000 0.945 0.055
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.055 0.945 0.000
S02.0 Fracture of vault of skull
0.000 0.946 0.054
S02.8 Fractures of other skull and facial bones
0.000 0.947 0.053
C15.3 Upper third of oesophagus
0.000 0.948 0.052
C25.7 Other parts of pancreas
0.000 0.948 0.052
E23.7 Disorder of pituitary gland, unspecified
0.000 0.949 0.051
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.051 0.949 0.000
S02.3 Fracture of orbital floor
0.000 0.950 0.050
S02.00 Fracture of vault of skull (closed)
0.000 0.951 0.049
C17.8 Overlapping lesion of small intestine
0.000 0.952 0.048
C17.3 Meckel's diverticulum
0.000 0.952 0.048
C21 Malignant neoplasm of anus and anal canal
0.000 0.952 0.048
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.952 0.048
S02.5 Fracture of tooth
0.000 0.952 0.048
C24.8 Overlapping lesion of biliary tract
0.000 0.952 0.048
S02.7 Multiple fractures involving skull and facial bones
0.000 0.953 0.047
S02.6 Fracture of mandible
0.000 0.953 0.047
E11.5 With peripheral circulatory complications
0.000 0.953 0.047
E27 Other disorders of adrenal gland
0.000 0.953 0.047
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.953 0.046
E23.1 Drug-induced hypopituitarism
0.000 0.953 0.046
E22.0 Acromegaly and pituitary gigantism
0.000 0.954 0.046
C24.9 Biliary tract, unspecified
0.000 0.954 0.046
C17.1 Jejunum
0.000 0.954 0.046
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.954 0.045
E04 Other non-toxic goitre
0.003 0.955 0.042
E26.0 Primary hyperaldosteronism
0.001 0.955 0.044
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.956 0.043
E83.4 Disorders of magnesium metabolism
0.039 0.957 0.004
E70-E90 Metabolic disorders
0.002 0.957 0.041
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.958 0.042
S02.30 Fracture of orbital floor (closed)
0.000 0.958 0.042
C23 Malignant neoplasm of gallbladder
0.000 0.958 0.042
S02.2 Fracture of nasal bones
0.000 0.959 0.041
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.960 0.040
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.961 0.039
S02.50 Fracture of tooth (closed)
0.000 0.961 0.039
S02.01 Fracture of vault of skull (open)
0.000 0.961 0.039
S02.81 Fractures of other skull and facial bones (open)
0.000 0.962 0.038
E78.2 Mixed hyperlipidaemia
0.000 0.962 0.038
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.962 0.038
S02.60 Fracture of mandible (closed)
0.000 0.963 0.037
E53.8 Deficiency of other specified B group vitamins
0.000 0.963 0.037
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.963 0.037
E78.5 Hyperlipidaemia, unspecified
0.000 0.963 0.037
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.964 0.036
S02.31 Fracture of orbital floor (open)
0.000 0.964 0.036
C17.9 Small intestine, unspecified
0.000 0.964 0.036
E27.1 Primary adrenocortical insufficiency
0.000 0.965 0.035
C21.2 Cloacogenic zone
0.000 0.965 0.035
S02.51 Fracture of tooth (open)
0.000 0.965 0.035
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.966 0.034
S02.61 Fracture of mandible (open)
0.000 0.966 0.034
E27.5 Adrenomedullary hyperfunction
0.000 0.966 0.034
E27.0 Other adrenocortical overactivity
0.000 0.966 0.034
S02.1 Fracture of base of skull
0.000 0.966 0.034
E73 Lactose intolerance
0.001 0.967 0.032
E78.1 Pure hyperglyceridaemia
0.000 0.967 0.033
S02.21 Fracture of nasal bones (open)
0.000 0.967 0.033
E04.8 Other specified non-toxic goitre
0.002 0.967 0.030
C17.2 Ileum
0.000 0.968 0.032
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.969 0.030
E78.6 Lipoprotein deficiency
0.000 0.969 0.031
E74 Other disorders of carbohydrate metabolism
0.001 0.969 0.030
E23.6 Other disorders of pituitary gland
0.001 0.969 0.030
E77 Disorders of glycoprotein metabolism
0.001 0.969 0.030
E76 Disorders of glycosaminoglycan metabolism
0.001 0.969 0.030
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.969 0.030
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.969 0.030
C26.8 Overlapping lesion of digestive system
0.000 0.969 0.030
C26.1 Spleen
0.000 0.969 0.030
E85 Amyloidosis
0.001 0.970 0.029
E78.3 Hyperchylomicronaemia
0.000 0.970 0.030
E27.9 Disorder of adrenal gland, unspecified
0.000 0.970 0.030
E70 Disorders of aromatic amino-acid metabolism
0.001 0.970 0.028
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.971 0.029
E88 Other metabolic disorders
0.001 0.971 0.028
C18 Malignant neoplasm of colon
0.000 0.971 0.029
E27.2 Addisonian crisis
0.000 0.971 0.029
C18.9 Colon, unspecified
0.000 0.971 0.029
E72 Other disorders of amino-acid metabolism
0.001 0.971 0.027
E79 Disorders of purine and pyrimidine metabolism
0.001 0.971 0.027
K90-K93 Other diseases of the digestive system
0.000 0.972 0.028
E23.2 Diabetes insipidus
0.000 0.972 0.028
C25.0 Head of pancreas
0.000 0.972 0.028
E11.4 With neurological complications
0.000 0.972 0.028
E84 Cystic fibrosis
0.001 0.972 0.026
C18.1 Appendix
0.000 0.973 0.027
E66 Obesity
0.000 0.973 0.027
C21.0 Anus, unspecified
0.000 0.973 0.027
E73.9 Lactose intolerance, unspecified
0.000 0.973 0.026
C24.1 Ampulla of Vater
0.001 0.974 0.026
C22.7 Other specified carcinomas of liver
0.000 0.974 0.026
C22.4 Other sarcomas of liver
0.000 0.974 0.026
C22.3 Angiosarcoma of liver
0.000 0.974 0.026
C22.2 Hepatoblastoma
0.000 0.974 0.026
C22.9 Liver, unspecified
0.000 0.974 0.026
C21.1 Anal canal
0.000 0.974 0.026
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.974 0.026
E78.4 Other hyperlipidaemia
0.000 0.974 0.026
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.974 0.026
E85.4 Organ-limited amyloidosis
0.000 0.976 0.024
E73.8 Other lactose intolerance
0.001 0.976 0.023
E73.1 Secondary lactase deficiency
0.001 0.976 0.023
E73.0 Congenital lactase deficiency
0.001 0.976 0.023
E88.9 Metabolic disorder, unspecified
0.000 0.976 0.024
S02.11 Fracture of base of skull (open)
0.000 0.976 0.024
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.976 0.023
H40.2 Primary angle-closure glaucoma
0.024 0.976 0.000
E75.5 Other lipid storage disorders
0.001 0.976 0.023
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.977 0.023
E75.6 Lipid storage disorder, unspecified
0.001 0.977 0.022
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.977 0.022
E75.3 Sphingolipidosis, unspecified
0.001 0.977 0.022
E75.1 Other gangliosidosis
0.001 0.977 0.022
E75.0 GM2 gangliosidosis
0.001 0.977 0.022
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.977 0.022
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.977 0.022
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.977 0.022
E74.2 Disorders of galactose metabolism
0.001 0.977 0.022
E74.1 Disorders of fructose metabolism
0.001 0.977 0.022
E27.8 Other specified disorders of adrenal gland
0.000 0.977 0.022
E71.3 Disorders of fatty-acid metabolism
0.001 0.978 0.021
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.978 0.021
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.978 0.021
E71.0 Maple-syrup-urine disease
0.001 0.978 0.021
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.978 0.021
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.978 0.021
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.978 0.021
E76.2 Other mucopolysaccharidoses
0.001 0.978 0.021
E76.1 Mucopolysaccharidosis, type II
0.001 0.978 0.021
E76.0 Mucopolysaccharidosis, type I
0.001 0.978 0.021
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.978 0.021
E77.8 Other disorders of glycoprotein metabolism
0.001 0.978 0.021
E77.1 Defects in glycoprotein degradation
0.001 0.978 0.021
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.978 0.021
C26.9 Ill-defined sites within the digestive system
0.000 0.978 0.022
E04.0 Non-toxic diffuse goitre
0.002 0.978 0.020
E75.2 Other sphingolipidosis
0.001 0.978 0.021
E85.3 Secondary systemic amyloidosis
0.001 0.978 0.022
C26.0 Intestinal tract, part unspecified
0.000 0.978 0.022
C22.1 Intrahepatic bile duct carcinoma
0.000 0.978 0.022
E74.0 Glycogen storage disease
0.001 0.978 0.021
C18.8 Overlapping lesion of colon
0.000 0.978 0.022
E88.2 Lipomatosis, not elsewhere classified
0.000 0.978 0.022
E85.8 Other amyloidosis
0.001 0.978 0.021
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.978 0.021
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.978 0.021
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.978 0.021
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.978 0.021
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.978 0.020
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.978 0.020
E70.2 Disorders of tyrosine metabolism
0.001 0.978 0.020
E70.1 Other hyperphenylalaninaemias
0.001 0.978 0.020
E70.0 Classical phenylketonuria
0.001 0.978 0.020
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.979 0.020
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.979 0.020
E72.5 Disorders of glycine metabolism
0.001 0.979 0.020
E72.4 Disorders of ornithine metabolism
0.001 0.979 0.020
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.979 0.020
E72.2 Disorders of urea cycle metabolism
0.001 0.979 0.020
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.979 0.020
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.979 0.020
E79.1 Lesch-Nyhan syndrome
0.001 0.979 0.020
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.979 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.979 0.020
S02.20 Fracture of nasal bones (closed)
0.000 0.980 0.020
E72.0 Disorders of amino-acid transport
0.001 0.980 0.019
C18.4 Transverse colon
0.000 0.980 0.020
E70.3 Albinism
0.001 0.980 0.019
E11.9 Without complications
0.000 0.980 0.020
E84.8 Cystic fibrosis with other manifestations
0.001 0.980 0.019
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.980 0.019
E66.1 Drug-induced obesity
0.000 0.980 0.020
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.980 0.019
E23.0 Hypopituitarism
0.000 0.980 0.019
I83.1 Varicose veins of lower extremities with inflammation
0.020 0.980 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.981 0.018
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.981 0.018
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.981 0.018
E88.8 Other specified metabolic disorders
0.001 0.982 0.018
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.982 0.017
E88.3 Tumour lysis syndrome
0.001 0.982 0.017
E84.9 Cystic fibrosis, unspecified
0.001 0.983 0.016
C16 Malignant neoplasm of stomach
0.000 0.983 0.017
E85.9 Amyloidosis, unspecified
0.001 0.983 0.016
E66.0 Obesity due to excess calories
0.000 0.984 0.016
C18.6 Descending colon
0.000 0.984 0.016

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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