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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130816
log Bayes Factor = 55.1018
Chromosome 6   position 29,203,911  (GRCh37) Explore rs3130816 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.009 0.991
E10.2 With renal complications
0.000 0.044 0.956
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.051 0.949
E10.1 With ketoacidosis
0.000 0.096 0.904
E10.4 With neurological complications
0.000 0.151 0.849
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.168 0.832
E16.1 Other hypoglycaemia
0.000 0.179 0.821
E05.8 Other thyrotoxicosis
0.000 0.196 0.804
E14 Unspecified diabetes mellitus
0.000 0.236 0.764
E13 Other specified diabetes mellitus
0.000 0.265 0.735
E10.7 With multiple complications
0.000 0.274 0.726
E40-E46 Malnutrition
0.000 0.276 0.724
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E10.0 With coma
0.000 0.288 0.712
E14.3 With ophthalmic complications
0.000 0.327 0.673
E10.6 With other specified complications
0.000 0.343 0.657
E07 Other disorders of thyroid
0.000 0.348 0.652
E06 Thyroiditis
0.000 0.356 0.644
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.357 0.642
E10.5 With peripheral circulatory complications
0.000 0.388 0.612
E14.1 With ketoacidosis
0.000 0.395 0.605
E14.8 With unspecified complications
0.000 0.397 0.603
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.412 0.588
E14.6 With other specified complications
0.000 0.412 0.588
E03 Other hypothyroidism
0.000 0.417 0.583
E14.4 With neurological complications
0.000 0.421 0.579
E13.9 Without complications
0.000 0.427 0.573
E10.8 With unspecified complications
0.000 0.439 0.561
E14.7 With multiple complications
0.000 0.452 0.548
E06.9 Thyroiditis, unspecified
0.000 0.464 0.536
E46 Unspecified protein-energy malnutrition
0.000 0.472 0.528
E13.8 With unspecified complications
0.000 0.473 0.527
E13.7 With multiple complications
0.000 0.473 0.527
E13.6 With other specified complications
0.000 0.473 0.527
E13.5 With peripheral circulatory complications
0.000 0.473 0.527
E13.4 With neurological complications
0.000 0.473 0.527
E13.2 With renal complications
0.000 0.473 0.527
E13.1 With ketoacidosis
0.000 0.473 0.527
E13.0 With coma
0.000 0.473 0.527
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.480 0.519
E45 Retarded development following protein-energy malnutrition
0.000 0.480 0.519
E43 Unspecified severe protein-energy malnutrition
0.000 0.480 0.519
E42 Marasmic kwashiorkor
0.000 0.480 0.519
E41 Nutritional marasmus
0.000 0.480 0.519
E40 Kwashiorkor
0.000 0.480 0.519
E07.8 Other specified disorders of thyroid
0.000 0.484 0.516
E14.0 With coma
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.513
E12.8 With unspecified complications
0.000 0.486 0.513
E12.7 With multiple complications
0.000 0.486 0.513
E12.6 With other specified complications
0.000 0.486 0.513
E12.5 With peripheral circulatory complications
0.000 0.486 0.513
E12.4 With neurological complications
0.000 0.486 0.513
E12.3 With ophthalmic complications
0.000 0.486 0.513
E12.2 With renal complications
0.000 0.486 0.513
E12.1 With ketoacidosis
0.000 0.486 0.513
E12.0 With coma
0.000 0.486 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E14.2 Withrenal complications
0.000 0.493 0.507
E14.5 With peripheral circulatory complications
0.000 0.498 0.502
E13.3 With ophthalmic complications
0.000 0.508 0.492
E06.1 Subacute thyroiditis
0.000 0.513 0.487
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.517 0.483
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.473 0.527 0.000
E07.1 Dyshormogenetic goitre
0.000 0.532 0.468
E07.0 Hypersecretion of calcitonin
0.000 0.532 0.468
E06.4 Drug-induced thyroiditis
0.000 0.538 0.462
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.538 0.462
E06.0 Acute thyroiditis
0.000 0.538 0.462
E06.5 Other chronic thyroiditis
0.000 0.552 0.448
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.560 0.440
K90 Intestinal malabsorption
0.000 0.564 0.436
E03.5 Myxoedema coma
0.000 0.581 0.418
E03.4 Atrophy of thyroid (acquired)
0.000 0.581 0.418
E03.3 Postinfectious hypothyroidism
0.000 0.581 0.418
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.586 0.414
E03.1 Congenital hypothyroidism without goitre
0.000 0.593 0.407
E03.9 Hypothyroidism, unspecified
0.000 0.617 0.383
E44.1 Mild protein-energy malnutrition
0.000 0.627 0.372
E44.0 Moderate protein-energy malnutrition
0.000 0.627 0.372
E65-E68 Obesity and other hyperalimentation
0.000 0.639 0.361
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.642 0.358
E03.8 Other specified hypothyroidism
0.000 0.672 0.328
E07.9 Disorder of thyroid, unspecified
0.000 0.683 0.317
K90.3 Pancreatic steatorrhoea
0.000 0.687 0.312
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.687 0.312
K90.1 Tropical sprue
0.000 0.687 0.312
K90.8 Other intestinal malabsorption
0.000 0.695 0.305
E50-E64 Other nutritional deficiencies
0.000 0.698 0.302
E67 Other hyperalimentation
0.000 0.741 0.259
E68 Sequelae of hyperalimentation
0.000 0.741 0.259
K90.9 Intestinal malabsorption, unspecified
0.000 0.746 0.254
E20-E35 Disorders of other endocrine glands
0.000 0.754 0.246
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.768 0.232
E21.3 Hyperparathyroidism, unspecified
0.000 0.773 0.227
E24 Cushing's syndrome
0.000 0.777 0.223
E65 Localised adiposity
0.000 0.779 0.220
E51 Thiamine deficiency
0.000 0.783 0.217
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.783 0.217
E50 Vitamin A deficiency
0.000 0.783 0.217
E60 Dietary zinc deficiency
0.000 0.783 0.217
E59 Dietary selenium deficiency
0.000 0.783 0.217
E52 Niacin deficiency [pellagra]
0.000 0.783 0.217
R31 Unspecified haematuria
0.215 0.785 0.000
E54 Ascorbic acid deficiency
0.000 0.787 0.213
E56 Other vitamin deficiencies
0.000 0.794 0.206
E58 Dietary calcium deficiency
0.000 0.800 0.200
E63 Other nutritional deficiencies
0.000 0.803 0.197
E55 Vitamin D deficiency
0.000 0.812 0.188
E24.0 Pituitary-dependent Cushing's disease
0.000 0.813 0.187
E67.8 Other specified hyperalimentation
0.000 0.814 0.186
E67.3 Hypervitaminosis D
0.000 0.814 0.186
E67.2 Megavitamin-B6 syndrome
0.000 0.814 0.186
E67.1 Hypercarotenaemia
0.000 0.814 0.186
E67.0 Hypervitaminosis A
0.000 0.814 0.186
E06.3 Autoimmune thyroiditis
0.000 0.815 0.185
E24.9 Cushing's syndrome, unspecified
0.000 0.816 0.184
E21.4 Other specified disorders of parathyroid gland
0.000 0.818 0.182
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.819 0.181
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.824 0.176
E32 Diseases of thymus
0.000 0.824 0.176
E30 Disorders of puberty, not elsewhere classified
0.000 0.824 0.176
E24.2 Drug-induced Cushing's syndrome
0.000 0.824 0.176
E20 Hypoparathyroidism
0.000 0.826 0.174
E61 Deficiency of other nutrient elements
0.000 0.828 0.172
E25 Adrenogenital disorders
0.000 0.828 0.172
E31 Polyglandular dysfunction
0.000 0.831 0.169
E21.2 Other hyperparathyroidism
0.000 0.832 0.168
E83 Disorders of mineral metabolism
0.161 0.835 0.004
E53 Deficiency of other B group vitamins
0.000 0.839 0.161
E24.8 Other Cushing's syndrome
0.000 0.840 0.160
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.840 0.160
E24.3 Ectopic ACTH syndrome
0.000 0.840 0.160
E24.1 Nelson's syndrome
0.000 0.840 0.160
M45.X9 Ankylosing spondylitis (Site unspecified)
0.159 0.841 0.000
E51.2 Wernicke's encephalopathy
0.000 0.844 0.156
E51.9 Thiamine deficiency, unspecified
0.000 0.844 0.156
E51.8 Other manifestations of thiamine deficiency
0.000 0.844 0.156
E51.1 Beriberi
0.000 0.844 0.156
E50.9 Vitamin A deficiency, unspecified
0.000 0.844 0.156
E50.8 Other manifestations of vitamin A deficiency
0.000 0.844 0.156
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.844 0.156
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.844 0.156
E50.5 Vitamin A deficiency with night blindness
0.000 0.844 0.156
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.844 0.156
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.844 0.156
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.844 0.156
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.844 0.156
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.844 0.156
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.844 0.156
E64.8 Sequelae of other nutritional deficiencies
0.000 0.844 0.156
E64.3 Sequelae of rickets
0.000 0.844 0.156
E64.2 Sequelae of vitamin C deficiency
0.000 0.844 0.156
E64.1 Sequelae of vitamin A deficiency
0.000 0.844 0.156
E64.0 Sequelae of protein-energy malnutrition
0.000 0.844 0.156
E28 Ovarian dysfunction
0.000 0.849 0.151
E56.9 Vitamin deficiency, unspecified
0.000 0.852 0.148
E56.8 Deficiency of other vitamins
0.000 0.852 0.148
E56.0 Deficiency of vitamin E
0.000 0.852 0.148
E29 Testicular dysfunction
0.000 0.855 0.145
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.855 0.145
E83.3 Disorders of phosphorus metabolism
0.141 0.858 0.001
E63.8 Other specified nutritional deficiencies
0.000 0.859 0.141
E63.1 Imbalance of constituents of food intake
0.000 0.859 0.141
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.859 0.141
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.861 0.139
E56.1 Deficiency of vitamin K
0.000 0.863 0.137
E11 Non-insulin-dependent diabetes mellitus
0.000 0.863 0.137
E55.0 Rickets, active
0.000 0.865 0.135
E14.9 Without complications
0.000 0.868 0.132
E34 Other endocrine disorders
0.000 0.869 0.131
E30.9 Disorder of puberty, unspecified
0.000 0.873 0.126
E30.8 Other disorders of puberty
0.000 0.873 0.126
E30.1 Precocious puberty
0.000 0.873 0.126
E30.0 Delayed puberty
0.000 0.873 0.126
E32.9 Disease of thymus, unspecified
0.000 0.873 0.126
E32.8 Other diseases of thymus
0.000 0.873 0.126
E32.1 Abscess of thymus
0.000 0.873 0.126
E32.0 Persistent hyperplasia of thymus
0.000 0.873 0.126
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.873 0.126
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.873 0.126
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.873 0.126
E53.9 Vitamin B deficiency, unspecified
0.000 0.875 0.125
E20.8 Other hypoparathyroidism
0.000 0.875 0.125
E20.1 Pseudohypoparathyroidism
0.000 0.875 0.125
E20.0 Idiopathic hypoparathyroidism
0.000 0.875 0.125
E11.6 With other specified complications
0.000 0.876 0.124
E61.9 Deficiency of nutrient element, unspecified
0.000 0.876 0.123
E61.8 Deficiency of other specified nutrient elements
0.000 0.876 0.123
E61.7 Deficiency of multiple nutrient elements
0.000 0.876 0.123
E61.6 Vanadium deficiency
0.000 0.876 0.123
E61.5 Molybdenum deficiency
0.000 0.876 0.123
E61.4 Chromium deficiency
0.000 0.876 0.123
E61.3 Manganese deficiency
0.000 0.876 0.123
E61.0 Copper deficiency
0.000 0.876 0.123
E25.9 Adrenogenital disorder, unspecified
0.000 0.877 0.123
E25.8 Other adrenogenital disorders
0.000 0.877 0.123
E20.9 Hypoparathyroidism, unspecified
0.000 0.878 0.122
E31.9 Polyglandular dysfunction, unspecified
0.000 0.879 0.121
E31.8 Other polyglandular dysfunction
0.000 0.879 0.121
E31.1 Polyglandular hyperfunction
0.000 0.879 0.121
E63.9 Nutritional deficiency, unspecified
0.000 0.879 0.121
E26 Hyperaldosteronism
0.000 0.880 0.119
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.881 0.119
E83.8 Other disorders of mineral metabolism
0.116 0.882 0.003
E83.2 Disorders of zinc metabolism
0.116 0.882 0.003
E83.0 Disorders of copper metabolism
0.116 0.882 0.003
E83.9 Disorder of mineral metabolism, unspecified
0.115 0.883 0.003
E53.1 Pyridoxine deficiency
0.000 0.884 0.116
E53.0 Riboflavin deficiency
0.000 0.884 0.116
E31.0 Autoimmune polyglandular failure
0.000 0.886 0.114
E28.9 Ovarian dysfunction, unspecified
0.000 0.892 0.108
E28.8 Other ovarian dysfunction
0.000 0.892 0.108
E28.1 Androgen excess
0.000 0.892 0.108
E28.0 Oestrogen excess
0.000 0.892 0.108
E22 Hyperfunction of pituitary gland
0.000 0.892 0.108
E55.9 Vitamin D deficiency, unspecified
0.000 0.893 0.107
E61.2 Magnesium deficiency
0.000 0.894 0.106
E21.0 Primary hyperparathyroidism
0.000 0.894 0.106
E29.9 Testicular dysfunction, unspecified
0.000 0.896 0.104
E29.8 Other testicular dysfunction
0.000 0.896 0.104
E29.0 Testicular hyperfunction
0.000 0.896 0.104
E61.1 Iron deficiency
0.000 0.897 0.103
E28.2 Polycystic ovarian syndrome
0.000 0.899 0.101
E11.2 With renal complications
0.000 0.899 0.101
E11.0 With coma
0.000 0.899 0.101
E11.1 With ketoacidosis
0.000 0.902 0.098
E11.7 With multiple complications
0.000 0.902 0.098
E34.5 Androgen resistance syndrome
0.000 0.906 0.094
E34.4 Constitutional tall stature
0.000 0.906 0.094
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.906 0.094
E34.1 Other hypersecretion of intestinal hormones
0.000 0.906 0.094
E28.3 Primary ovarian failure
0.000 0.907 0.092
C20 Malignant neoplasm of rectum
0.000 0.907 0.093
E34.3 Short stature, not elsewhere classified
0.000 0.908 0.092
C15-C26 Malignant neoplasms of digestive organs
0.000 0.909 0.091
E34.9 Endocrine disorder, unspecified
0.000 0.909 0.090
E26.8 Other hyperaldosteronism
0.000 0.914 0.086
E26.1 Secondary hyperaldosteronism
0.000 0.914 0.086
E34.0 Carcinoid syndrome
0.000 0.915 0.085
I83 Varicose veins of lower extremities
0.085 0.915 0.000
C25 Malignant neoplasm of pancreas
0.000 0.918 0.082
E11.8 With unspecified complications
0.000 0.919 0.081
C15 Malignant neoplasm of oesophagus
0.000 0.919 0.081
E22.8 Other hyperfunction of pituitary gland
0.000 0.923 0.077
E22.1 Hyperprolactinaemia
0.000 0.924 0.076
E26.9 Hyperaldosteronism, unspecified
0.000 0.924 0.076
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.924 0.076
E34.8 Other specified endocrine disorders
0.000 0.925 0.075
M45 Ankylosing spondylitis
0.074 0.926 0.000
E29.1 Testicular hypofunction
0.000 0.927 0.073
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.927 0.073
C17 Malignant neoplasm of small intestine
0.000 0.930 0.070
C25.1 Body of pancreas
0.000 0.930 0.070
C15.5 Lower third of oesophagus
0.000 0.930 0.070
C15.4 Middle third of oesophagus
0.000 0.931 0.069
C25.3 Pancreatic duct
0.000 0.931 0.069
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.932 0.067
C25.2 Tail of pancreas
0.000 0.933 0.067
C17.0 Duodenum
0.000 0.933 0.067
S02.4 Fracture of malar and maxillary bones
0.000 0.936 0.064
C25.4 Endocrine pancreas
0.000 0.936 0.064
E23 Hypofunction and other disorders of pituitary gland
0.000 0.938 0.062
C25.8 Overlapping lesion of pancreas
0.000 0.938 0.062
C25.9 Pancreas, unspecified
0.000 0.939 0.061
C15.0 Cervical part of oesophagus
0.000 0.939 0.061
C24.0 Extrahepatic bile duct
0.000 0.939 0.061
C15.9 Oesophagus, unspecified
0.000 0.940 0.060
M45.X2 Ankylosing spondylitis (Cervical region)
0.059 0.940 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.058 0.942 0.000
C15.8 Overlapping lesion of oesophagus
0.000 0.942 0.058
C15.2 Abdominal part of oesophagus
0.000 0.942 0.058
E22.0 Acromegaly and pituitary gigantism
0.000 0.942 0.057
S02 Fracture of skull and facial bones
0.000 0.943 0.057
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.943 0.057
M45.X6 Ankylosing spondylitis (Lumbar region)
0.057 0.943 0.000
C15.1 Thoracic part of oesophagus
0.000 0.943 0.057
C25.7 Other parts of pancreas
0.000 0.946 0.054
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.053 0.946 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.053 0.946 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.053 0.946 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.053 0.946 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.053 0.946 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.053 0.946 0.000
C21 Malignant neoplasm of anus and anal canal
0.000 0.947 0.053
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.053 0.947 0.000
Z71.8 Other specified counselling
0.053 0.947 0.000
E11.3 With ophthalmic complications
0.000 0.948 0.052
S02.0 Fracture of vault of skull
0.000 0.949 0.051
E11.5 With peripheral circulatory complications
0.000 0.949 0.051
C17.8 Overlapping lesion of small intestine
0.000 0.949 0.050
C17.3 Meckel's diverticulum
0.000 0.949 0.050
E83.4 Disorders of magnesium metabolism
0.048 0.950 0.002
E26.0 Primary hyperaldosteronism
0.001 0.951 0.049
S02.8 Fractures of other skull and facial bones
0.000 0.951 0.049
E23.7 Disorder of pituitary gland, unspecified
0.000 0.951 0.049
C24.8 Overlapping lesion of biliary tract
0.000 0.951 0.048
C15.3 Upper third of oesophagus
0.000 0.951 0.048
E04 Other non-toxic goitre
0.002 0.952 0.046
C17.1 Jejunum
0.000 0.952 0.048
C24.9 Biliary tract, unspecified
0.000 0.953 0.047
S02.3 Fracture of orbital floor
0.000 0.953 0.047
S02.00 Fracture of vault of skull (closed)
0.000 0.954 0.046
S02.6 Fracture of mandible
0.000 0.954 0.046
S02.7 Multiple fractures involving skull and facial bones
0.000 0.954 0.046
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.955 0.044
E23.1 Drug-induced hypopituitarism
0.000 0.955 0.044
S02.5 Fracture of tooth
0.000 0.956 0.044
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.956 0.044
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.957 0.043
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.957 0.043
C23 Malignant neoplasm of gallbladder
0.000 0.957 0.042
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.958 0.042
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.958 0.042
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.041 0.959 0.000
E27 Other disorders of adrenal gland
0.000 0.960 0.040
S02.30 Fracture of orbital floor (closed)
0.000 0.960 0.040
S02.2 Fracture of nasal bones
0.000 0.961 0.039
S02.60 Fracture of mandible (closed)
0.000 0.961 0.038
C21.2 Cloacogenic zone
0.000 0.962 0.038
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.962 0.038
C17.9 Small intestine, unspecified
0.000 0.962 0.037
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.963 0.037
S02.01 Fracture of vault of skull (open)
0.000 0.963 0.037
S02.81 Fractures of other skull and facial bones (open)
0.000 0.964 0.035
S02.50 Fracture of tooth (closed)
0.000 0.965 0.035
E04.8 Other specified non-toxic goitre
0.002 0.965 0.033
S02.31 Fracture of orbital floor (open)
0.000 0.966 0.034
C18.9 Colon, unspecified
0.000 0.966 0.034
S02.61 Fracture of mandible (open)
0.000 0.967 0.033
E11.4 With neurological complications
0.000 0.967 0.033
C18 Malignant neoplasm of colon
0.000 0.967 0.033
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.967 0.033
C22.9 Liver, unspecified
0.000 0.967 0.033
E53.8 Deficiency of other specified B group vitamins
0.000 0.967 0.033
C25.0 Head of pancreas
0.000 0.968 0.032
S02.21 Fracture of nasal bones (open)
0.000 0.968 0.032
S02.51 Fracture of tooth (open)
0.000 0.968 0.032
C18.1 Appendix
0.000 0.968 0.032
C17.2 Ileum
0.000 0.969 0.031
C26.8 Overlapping lesion of digestive system
0.000 0.969 0.031
C26.1 Spleen
0.000 0.969 0.031
S02.1 Fracture of base of skull
0.000 0.969 0.031
C22.7 Other specified carcinomas of liver
0.000 0.969 0.031
C22.4 Other sarcomas of liver
0.000 0.969 0.031
C22.3 Angiosarcoma of liver
0.000 0.969 0.031
C22.2 Hepatoblastoma
0.000 0.969 0.031
C21.1 Anal canal
0.000 0.970 0.030
C21.0 Anus, unspecified
0.000 0.970 0.029
E27.5 Adrenomedullary hyperfunction
0.000 0.971 0.029
E27.0 Other adrenocortical overactivity
0.000 0.971 0.029
E27.1 Primary adrenocortical insufficiency
0.000 0.971 0.029
K90-K93 Other diseases of the digestive system
0.000 0.972 0.028
E23.6 Other disorders of pituitary gland
0.001 0.972 0.027
E66 Obesity
0.000 0.972 0.028
C22.1 Intrahepatic bile duct carcinoma
0.000 0.973 0.027
E23.2 Diabetes insipidus
0.000 0.973 0.027
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.973 0.027
C24.1 Ampulla of Vater
0.001 0.973 0.026
E27.9 Disorder of adrenal gland, unspecified
0.000 0.974 0.026
C18.8 Overlapping lesion of colon
0.000 0.975 0.025
I83.1 Varicose veins of lower extremities with inflammation
0.025 0.975 0.000
E04.0 Non-toxic diffuse goitre
0.002 0.975 0.023
E27.2 Addisonian crisis
0.000 0.975 0.025
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.024 0.976 0.000
E70-E90 Metabolic disorders
0.003 0.977 0.020
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.977 0.023
C26.9 Ill-defined sites within the digestive system
0.000 0.977 0.022
C26.0 Intestinal tract, part unspecified
0.000 0.977 0.022
S02.11 Fracture of base of skull (open)
0.000 0.978 0.022
K14.8 Other diseases of tongue
0.000 0.978 0.022
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.980 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.980 0.020
C18.4 Transverse colon
0.000 0.980 0.020
E66.1 Drug-induced obesity
0.000 0.980 0.020
E11.9 Without complications
0.000 0.980 0.020
C16 Malignant neoplasm of stomach
0.000 0.981 0.019
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.982 0.018
E27.8 Other specified disorders of adrenal gland
0.000 0.982 0.018
E78.2 Mixed hyperlipidaemia
0.000 0.982 0.018
E23.0 Hypopituitarism
0.000 0.982 0.017
C18.7 Sigmoid colon
0.000 0.983 0.017
S02.20 Fracture of nasal bones (closed)
0.000 0.983 0.017
C18.6 Descending colon
0.000 0.983 0.017
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.983 0.015
E73 Lactose intolerance
0.002 0.983 0.015
E77 Disorders of glycoprotein metabolism
0.002 0.983 0.015
E76 Disorders of glycosaminoglycan metabolism
0.002 0.983 0.015
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.002 0.983 0.015
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.002 0.983 0.015
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.983 0.016
E74 Other disorders of carbohydrate metabolism
0.002 0.983 0.015
E66.0 Obesity due to excess calories
0.000 0.984 0.016
E70 Disorders of aromatic amino-acid metabolism
0.002 0.984 0.014
S05 Injury of eye and orbit
0.000 0.984 0.016
E85 Amyloidosis
0.002 0.984 0.014
S00-S09 Injuries to the head
0.000 0.984 0.016
E78.5 Hyperlipidaemia, unspecified
0.000 0.984 0.016
E72 Other disorders of amino-acid metabolism
0.002 0.984 0.013
E79 Disorders of purine and pyrimidine metabolism
0.002 0.984 0.013
E78.1 Pure hyperglyceridaemia
0.000 0.984 0.016
E84 Cystic fibrosis
0.002 0.985 0.013
E88 Other metabolic disorders
0.001 0.985 0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.985 0.015
K93.1 Megacolon in Chagas' disease
0.000 0.985 0.015
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.985 0.015
E78.6 Lipoprotein deficiency
0.000 0.985 0.015
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.985 0.015
E78.3 Hyperchylomicronaemia
0.000 0.986 0.014
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.986 0.014
C18.3 Hepatic flexure
0.000 0.986 0.014
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.986 0.014
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.986 0.014
S02.10 Fracture of base of skull (closed)
0.000 0.986 0.014
S05.8 Other injuries of eye and orbit
0.000 0.986 0.014
C16.5 Lesser curvature of stomach, unspecified
0.000 0.987 0.013
C16.8 Overlapping lesion of stomach
0.000 0.987 0.013
C16.2 Body of stomach
0.000 0.987 0.013
E75.5 Other lipid storage disorders
0.001 0.987 0.011
E85.4 Organ-limited amyloidosis
0.001 0.987 0.012
C16.6 Greater curvature of stomach, unspecified
0.000 0.987 0.012
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.988 0.012
E73.9 Lactose intolerance, unspecified
0.001 0.988 0.012
E88.9 Metabolic disorder, unspecified
0.001 0.988 0.012
E75.6 Lipid storage disorder, unspecified
0.002 0.988 0.011
E75.4 Neuronal ceroid lipofuscinosis
0.002 0.988 0.011
E75.3 Sphingolipidosis, unspecified
0.002 0.988 0.011
E75.1 Other gangliosidosis
0.002 0.988 0.011
E75.0 GM2 gangliosidosis
0.002 0.988 0.011
E73.8 Other lactose intolerance
0.001 0.988 0.011
E73.1 Secondary lactase deficiency
0.001 0.988 0.011
E73.0 Congenital lactase deficiency
0.001 0.988 0.011
E71.3 Disorders of fatty-acid metabolism
0.002 0.988 0.011
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.988 0.011
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.988 0.011
E71.0 Maple-syrup-urine disease
0.002 0.988 0.011
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.988 0.011
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.988 0.011
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.988 0.011
E76.2 Other mucopolysaccharidoses
0.002 0.988 0.011
E76.1 Mucopolysaccharidosis, type II
0.002 0.988 0.011
E76.0 Mucopolysaccharidosis, type I
0.002 0.988 0.011
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.988 0.011
E77.8 Other disorders of glycoprotein metabolism
0.002 0.988 0.011
E77.1 Defects in glycoprotein degradation
0.002 0.988 0.011
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.988 0.011
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.988 0.011
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.988 0.011
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.988 0.011
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.988 0.011
E74.2 Disorders of galactose metabolism
0.001 0.988 0.011
E74.1 Disorders of fructose metabolism
0.001 0.988 0.011
C16.4 Pylorus
0.000 0.988 0.012
E75.2 Other sphingolipidosis
0.002 0.988 0.011
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.988 0.012
E78.4 Other hyperlipidaemia
0.000 0.988 0.012
S00 Superficial injury of head
0.000 0.988 0.012
E74.0 Glycogen storage disease
0.001 0.988 0.011
C16.0 Cardia
0.000 0.988 0.012
C16.9 Stomach, unspecified
0.000 0.988 0.012
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.988 0.010
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.988 0.010
E70.2 Disorders of tyrosine metabolism
0.002 0.988 0.010
E70.1 Other hyperphenylalaninaemias
0.002 0.988 0.010
E70.0 Classical phenylketonuria
0.002 0.988 0.010
E85.3 Secondary systemic amyloidosis
0.001 0.988 0.011
H40.2 Primary angle-closure glaucoma
0.012 0.988 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.988 0.012
S05.7 Avulsion of eye
0.000 0.988 0.012
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.988 0.012
E04.9 Non-toxic goitre, unspecified
0.001 0.988 0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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