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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130931
log Bayes Factor = 102.978
Chromosome 6   position 31,134,888  (GRCh37) Explore rs3130931 on Ensembl!
Variant rs3130931 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
0.999 0.001 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.002 0.998
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.007 0.993
E83.1 Disorders of iron metabolism
0.989 0.011 0.000
E10.3 With ophthalmic complications
0.000 0.021 0.979
E11.9 Without complications
0.000 0.022 0.978
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.022 0.978
E14 Unspecified diabetes mellitus
0.000 0.023 0.977
E11 Non-insulin-dependent diabetes mellitus
0.000 0.023 0.977
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.027 0.973
E07 Other disorders of thyroid
0.000 0.061 0.939
G35 Multiple sclerosis
0.930 0.070 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.071 0.929
E14.3 With ophthalmic complications
0.000 0.075 0.925
E07.9 Disorder of thyroid, unspecified
0.000 0.094 0.906
E11.0 With coma
0.000 0.105 0.895
L40.0 Psoriasis vulgaris
0.895 0.105 0.000
E10.1 With ketoacidosis
0.000 0.122 0.878
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.125 0.875
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.133 0.867
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.137 0.863
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.141 0.859
E14.9 Without complications
0.000 0.160 0.840
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.161 0.839
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.180 0.820
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.194 0.806
E10.6 With other specified complications
0.000 0.206 0.794
K90 Intestinal malabsorption
0.000 0.208 0.792
L40.3 Pustulosis palmaris et plantaris
0.792 0.208 0.000
E10.4 With neurological complications
0.000 0.209 0.791
E10.0 With coma
0.000 0.211 0.789
L40.1 Generalised pustular psoriasis
0.775 0.225 0.000
E03.8 Other specified hypothyroidism
0.000 0.227 0.773
E16 Other disorders of pancreatic internal secretion
0.000 0.231 0.769
E14.6 With other specified complications
0.000 0.241 0.759
E10.2 With renal complications
0.000 0.242 0.758
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.248 0.752
J45.9 Asthma, unspecified
0.000 0.254 0.746
E14.5 With peripheral circulatory complications
0.000 0.258 0.742
E14.2 Withrenal complications
0.000 0.261 0.739
E14.1 With ketoacidosis
0.000 0.263 0.737
E13 Other specified diabetes mellitus
0.000 0.265 0.735
E10.8 With unspecified complications
0.000 0.269 0.731
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.270 0.729
E10.5 With peripheral circulatory complications
0.000 0.281 0.719
L40.4 Guttate psoriasis
0.718 0.281 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E14.7 With multiple complications
0.000 0.299 0.701
E14.0 With coma
0.000 0.299 0.701
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.299 0.701
E11.7 With multiple complications
0.000 0.300 0.700
E40-E46 Malnutrition
0.000 0.302 0.698
E14.8 With unspecified complications
0.000 0.302 0.697
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.304 0.696
E05.8 Other thyrotoxicosis
0.000 0.313 0.687
G35-G37 Demyelinating diseases of the central nervous system
0.685 0.315 0.000
E07.1 Dyshormogenetic goitre
0.000 0.327 0.673
E07.0 Hypersecretion of calcitonin
0.000 0.327 0.673
K90.9 Intestinal malabsorption, unspecified
0.000 0.327 0.673
E16.2 Hypoglycaemia, unspecified
0.000 0.350 0.650
E03.1 Congenital hypothyroidism without goitre
0.000 0.355 0.644
E14.4 With neurological complications
0.000 0.360 0.639
E11.8 With unspecified complications
0.000 0.361 0.639
G37 Other demyelinating diseases of central nervous system
0.626 0.374 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.380 0.620
E15 Nondiabetic hypoglycaemic coma
0.000 0.381 0.618
L40.8 Other psoriasis
0.616 0.384 0.000
E16.1 Other hypoglycaemia
0.000 0.409 0.591
E11.1 With ketoacidosis
0.000 0.410 0.589
K90.8 Other intestinal malabsorption
0.000 0.414 0.586
G37.9 Demyelinating disease of central nervous system, unspecified
0.582 0.417 0.000
E07.8 Other specified disorders of thyroid
0.000 0.422 0.578
K90.3 Pancreatic steatorrhoea
0.000 0.432 0.568
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.432 0.568
K90.1 Tropical sprue
0.000 0.432 0.568
E11.2 With renal complications
0.000 0.433 0.566
E13.9 Without complications
0.000 0.438 0.562
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.448 0.551
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.448 0.551
E16.4 Abnormal secretion of gastrin
0.000 0.448 0.551
E16.3 Increased secretion of glucagon
0.000 0.448 0.551
E13.8 With unspecified complications
0.000 0.473 0.527
E13.7 With multiple complications
0.000 0.473 0.527
E13.6 With other specified complications
0.000 0.473 0.527
E13.5 With peripheral circulatory complications
0.000 0.473 0.527
E13.4 With neurological complications
0.000 0.473 0.527
E13.2 With renal complications
0.000 0.473 0.527
E13.1 With ketoacidosis
0.000 0.473 0.527
E13.0 With coma
0.000 0.473 0.527
G36 Other acute disseminated demyelination
0.517 0.482 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E13.3 With ophthalmic complications
0.000 0.494 0.506
G37.8 Other specified demyelinating diseases of central nervous system
0.505 0.495 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.496 0.503
E11.5 With peripheral circulatory complications
0.000 0.497 0.503
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.499 0.500
E45 Retarded development following protein-energy malnutrition
0.000 0.499 0.500
E43 Unspecified severe protein-energy malnutrition
0.000 0.499 0.500
E42 Marasmic kwashiorkor
0.000 0.499 0.500
E41 Nutritional marasmus
0.000 0.499 0.500
E40 Kwashiorkor
0.000 0.499 0.500
E46 Unspecified protein-energy malnutrition
0.000 0.513 0.487
E06 Thyroiditis
0.000 0.543 0.456
E11.6 With other specified complications
0.000 0.550 0.449
G37.5 Concentric sclerosis [Balo]
0.449 0.551 0.000
G37.4 Subacute necrotising myelitis
0.449 0.551 0.000
G37.2 Central pontine myelinolysis
0.449 0.551 0.000
G37.1 Central demyelination of corpus callosum
0.449 0.551 0.000
G37.0 Diffuse sclerosis
0.449 0.551 0.000
M06 Other rheumatoid arthritis
0.001 0.578 0.422
G36.0 Neuromyelitis optica [Devic]
0.397 0.603 0.000
E50-E64 Other nutritional deficiencies
0.000 0.608 0.392
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.380 0.620 0.000
G36.9 Acute disseminated demyelination, unspecified
0.371 0.629 0.000
G36.8 Other specified acute disseminated demyelination
0.371 0.629 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.371 0.629 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.641 0.359
E44.0 Moderate protein-energy malnutrition
0.000 0.641 0.359
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.648 0.351
M06.3 Rheumatoid nodule
0.000 0.651 0.349
E06.5 Other chronic thyroiditis
0.000 0.652 0.348
E06.4 Drug-induced thyroiditis
0.000 0.672 0.327
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.672 0.327
E06.0 Acute thyroiditis
0.000 0.672 0.327
E06.1 Subacute thyroiditis
0.000 0.674 0.325
M06.4 Inflammatory polyarthropathy
0.000 0.676 0.323
E65-E68 Obesity and other hyperalimentation
0.000 0.679 0.321
M06.34 Rheumatoid nodule (Hand)
0.000 0.689 0.311
M06.2 Rheumatoid bursitis
0.001 0.697 0.303
M06.1 Adult-onset Still's disease
0.001 0.697 0.303
M06.8 Other specified rheumatoid arthritis
0.001 0.702 0.298
E58 Dietary calcium deficiency
0.000 0.711 0.289
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.719 0.281
E63 Other nutritional deficiencies
0.000 0.719 0.281
E50 Vitamin A deficiency
0.000 0.719 0.281
E60 Dietary zinc deficiency
0.000 0.719 0.281
E59 Dietary selenium deficiency
0.000 0.719 0.281
E54 Ascorbic acid deficiency
0.000 0.719 0.281
E52 Niacin deficiency [pellagra]
0.000 0.719 0.281
E61 Deficiency of other nutrient elements
0.000 0.722 0.278
E56 Other vitamin deficiencies
0.000 0.730 0.270
E51 Thiamine deficiency
0.000 0.732 0.268
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.732 0.268
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.739 0.261
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.749 0.250
M06.38 Rheumatoid nodule (Other)
0.000 0.749 0.250
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.749 0.250
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.749 0.250
M06.33 Rheumatoid nodule (Forearm)
0.000 0.749 0.250
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.749 0.250
L40-L45 Papulosquamous disorders
0.237 0.761 0.002
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.767 0.233
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.768 0.232
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.768 0.232
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.768 0.232
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.768 0.232
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.768 0.232
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.768 0.232
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.768 0.232
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.768 0.232
E67 Other hyperalimentation
0.000 0.770 0.230
E68 Sequelae of hyperalimentation
0.000 0.770 0.230
E06.3 Autoimmune thyroiditis
0.000 0.770 0.230
E55 Vitamin D deficiency
0.000 0.778 0.222
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.779 0.221
M06.19 Adult-onset Still's disease (Site unspecified)
0.001 0.782 0.217
M06.18 Adult-onset Still's disease (Other)
0.001 0.782 0.217
M06.17 Adult-onset Still's disease (Ankle and foot)
0.001 0.782 0.217
M06.16 Adult-onset Still's disease (Lower leg)
0.001 0.782 0.217
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.001 0.782 0.217
M06.14 Adult-onset Still's disease (Hand)
0.001 0.782 0.217
M06.13 Adult-onset Still's disease (Forearm)
0.001 0.782 0.217
M06.12 Adult-onset Still's disease (Upper arm)
0.001 0.782 0.217
M06.11 Adult-onset Still's disease (Shoulder region)
0.001 0.782 0.217
M06.10 Adult-onset Still's disease (Multiple sites)
0.001 0.782 0.217
M06.29 Rheumatoid bursitis (Site unspecified)
0.001 0.782 0.217
M06.28 Rheumatoid bursitis (Other)
0.001 0.782 0.217
M06.27 Rheumatoid bursitis (Ankle and foot)
0.001 0.782 0.217
M06.26 Rheumatoid bursitis (Lower leg)
0.001 0.782 0.217
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.001 0.782 0.217
M06.24 Rheumatoid bursitis (Hand)
0.001 0.782 0.217
M06.23 Rheumatoid bursitis (Forearm)
0.001 0.782 0.217
M06.22 Rheumatoid bursitis (Upper arm)
0.001 0.782 0.217
M06.21 Rheumatoid bursitis (Shoulder region)
0.001 0.782 0.217
M06.20 Rheumatoid bursitis (Multiple sites)
0.001 0.782 0.217
K60.2 Anal fissure, unspecified
0.000 0.783 0.217
M06.88 Other specified rheumatoid arthritis (Other)
0.001 0.786 0.213
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.001 0.786 0.213
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.001 0.786 0.213
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.001 0.786 0.213
M06.84 Other specified rheumatoid arthritis (Hand)
0.001 0.786 0.213
M06.83 Other specified rheumatoid arthritis (Forearm)
0.001 0.786 0.213
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.001 0.786 0.213
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.001 0.786 0.213
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.001 0.786 0.213
M06.30 Rheumatoid nodule (Multiple sites)
0.001 0.789 0.210
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.001 0.791 0.208
E50.9 Vitamin A deficiency, unspecified
0.000 0.798 0.201
E50.8 Other manifestations of vitamin A deficiency
0.000 0.798 0.201
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.798 0.201
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.798 0.201
E50.5 Vitamin A deficiency with night blindness
0.000 0.798 0.201
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.798 0.201
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.798 0.201
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.798 0.201
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.798 0.201
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.798 0.201
E63.9 Nutritional deficiency, unspecified
0.000 0.798 0.201
E63.8 Other specified nutritional deficiencies
0.000 0.798 0.201
E63.1 Imbalance of constituents of food intake
0.000 0.798 0.201
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.798 0.201
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.798 0.201
E64.8 Sequelae of other nutritional deficiencies
0.000 0.798 0.201
E64.3 Sequelae of rickets
0.000 0.798 0.201
E64.2 Sequelae of vitamin C deficiency
0.000 0.798 0.201
E64.1 Sequelae of vitamin A deficiency
0.000 0.798 0.201
E64.0 Sequelae of protein-energy malnutrition
0.000 0.798 0.201
C83.3 Large cell (diffuse)
0.000 0.799 0.201
E61.2 Magnesium deficiency
0.000 0.800 0.200
E61.9 Deficiency of nutrient element, unspecified
0.000 0.800 0.200
E61.8 Deficiency of other specified nutrient elements
0.000 0.800 0.200
E61.7 Deficiency of multiple nutrient elements
0.000 0.800 0.200
E61.6 Vanadium deficiency
0.000 0.800 0.200
E61.5 Molybdenum deficiency
0.000 0.800 0.200
E61.4 Chromium deficiency
0.000 0.800 0.200
E61.3 Manganese deficiency
0.000 0.800 0.200
E61.0 Copper deficiency
0.000 0.800 0.200
E11.3 With ophthalmic complications
0.000 0.802 0.198
E61.1 Iron deficiency
0.000 0.804 0.196
E06.9 Thyroiditis, unspecified
0.001 0.805 0.195
E56.9 Vitamin deficiency, unspecified
0.000 0.806 0.194
E56.8 Deficiency of other vitamins
0.000 0.806 0.194
E56.0 Deficiency of vitamin E
0.000 0.806 0.194
E51.9 Thiamine deficiency, unspecified
0.000 0.807 0.192
E51.8 Other manifestations of thiamine deficiency
0.000 0.807 0.192
E51.1 Beriberi
0.000 0.807 0.192
M06.0 Seronegative rheumatoid arthritis
0.000 0.809 0.190
E56.1 Deficiency of vitamin K
0.000 0.817 0.183
J45 Asthma
0.000 0.817 0.183
E51.2 Wernicke's encephalopathy
0.000 0.820 0.179
E11.4 With neurological complications
0.000 0.820 0.179
E83 Disorders of mineral metabolism
0.170 0.828 0.002
L44 Other papulosquamous disorders
0.170 0.828 0.001
L41 Parapsoriasis
0.170 0.828 0.001
L45 Papulosquamous disorders in diseases classified elsewhere
0.170 0.828 0.001
E67.8 Other specified hyperalimentation
0.000 0.835 0.165
E67.3 Hypervitaminosis D
0.000 0.835 0.165
E67.2 Megavitamin-B6 syndrome
0.000 0.835 0.165
E67.1 Hypercarotenaemia
0.000 0.835 0.165
E67.0 Hypervitaminosis A
0.000 0.835 0.165
E65 Localised adiposity
0.000 0.835 0.165
E55.0 Rickets, active
0.000 0.840 0.159
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.843 0.157
C85.1 B-cell lymphoma, unspecified
0.000 0.843 0.157
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.844 0.156
L42 Pityriasis rosea
0.152 0.846 0.002
E53 Deficiency of other B group vitamins
0.000 0.852 0.148
E20-E35 Disorders of other endocrine glands
0.000 0.853 0.147
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.858 0.142
J45.8 Mixed asthma
0.000 0.861 0.139
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.863 0.137
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.863 0.137
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.863 0.137
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.863 0.137
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.864 0.135
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.001 0.865 0.134
E83.3 Disorders of phosphorus metabolism
0.133 0.866 0.001
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.870 0.129
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.871 0.129
E24 Cushing's syndrome
0.000 0.871 0.129
E83.9 Disorder of mineral metabolism, unspecified
0.127 0.872 0.002
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.873 0.127
E83.8 Other disorders of mineral metabolism
0.122 0.877 0.002
E83.2 Disorders of zinc metabolism
0.122 0.877 0.002
E83.0 Disorders of copper metabolism
0.122 0.877 0.002
L41.9 Parapsoriasis, unspecified
0.122 0.877 0.001
L41.8 Other parapsoriasis
0.122 0.877 0.001
L41.5 Retiform parapsoriasis
0.122 0.877 0.001
L41.4 Large plaque parapsoriasis
0.122 0.877 0.001
L41.3 Small plaque parapsoriasis
0.122 0.877 0.001
L41.2 Lymphomatoid papulosis
0.122 0.877 0.001
L41.1 Pityriasis lichenoides chronica
0.122 0.877 0.001
L41.0 Pityriasis lichenoides et varioliformis acuta
0.122 0.877 0.001
L44.9 Papulosquamous disorder, unspecified
0.122 0.877 0.001
L44.8 Other specified papulosquamous disorders
0.122 0.877 0.001
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.122 0.877 0.001
L44.3 Lichen ruber moniliformis
0.122 0.877 0.001
L44.2 Lichen striatus
0.122 0.877 0.001
L44.1 Lichen nitidus
0.122 0.877 0.001
L44.0 Pityriasis rubra pilaris
0.122 0.877 0.001
J45.1 Nonallergic asthma
0.000 0.879 0.121
E28 Ovarian dysfunction
0.000 0.881 0.119
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.001 0.881 0.118
K60 Fissure and fistula of anal and rectal regions
0.000 0.885 0.115
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.885 0.115
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.885 0.115
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.887 0.113
C85.0 Lymphosarcoma
0.000 0.887 0.113
J33.9 Nasal polyp, unspecified
0.000 0.887 0.113
C83.7 Burkitt's tumour
0.000 0.888 0.112
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.888 0.112
K60.0 Acute anal fissure
0.000 0.888 0.112
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.890 0.110
E25 Adrenogenital disorders
0.000 0.892 0.107
E24.2 Drug-induced Cushing's syndrome
0.000 0.893 0.107
C81 Hodgkin's disease
0.000 0.893 0.107
J33 Nasal polyp
0.000 0.893 0.107
E24.0 Pituitary-dependent Cushing's disease
0.000 0.893 0.106
E53.1 Pyridoxine deficiency
0.000 0.894 0.106
E53.0 Riboflavin deficiency
0.000 0.894 0.106
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.895 0.105
E32 Diseases of thymus
0.000 0.895 0.105
E31 Polyglandular dysfunction
0.000 0.895 0.105
E30 Disorders of puberty, not elsewhere classified
0.000 0.895 0.105
J33.8 Other polyp of sinus
0.000 0.895 0.105
C83.6 Undifferentiated (diffuse)
0.000 0.898 0.102
C83.5 Lymphoblastic (diffuse)
0.000 0.898 0.102
C83.4 Immunoblastic (diffuse)
0.000 0.898 0.102
C83.2 Mixed small and large cell (diffuse)
0.000 0.898 0.102
C86 Other specified types of T/NK-cell lymphoma
0.001 0.898 0.101
E28.2 Polycystic ovarian syndrome
0.000 0.898 0.102
E23 Hypofunction and other disorders of pituitary gland
0.000 0.899 0.101
E55.9 Vitamin D deficiency, unspecified
0.000 0.899 0.101
M07.3 Other psoriatic arthropathies
0.097 0.902 0.000
L43 Lichen planus
0.091 0.903 0.006
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.001 0.903 0.097
M07.30 Other psoriatic arthropathies (Multiple sites)
0.097 0.903 0.000
C92 Myeloid leukaemia
0.001 0.903 0.096
C81.9 Hodgkin's disease, unspecified
0.000 0.903 0.097
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.905 0.095
E24.9 Cushing's syndrome, unspecified
0.000 0.905 0.095
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.906 0.094
M07.39 Other psoriatic arthropathies (Site unspecified)
0.093 0.907 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.908 0.092
E24.3 Ectopic ACTH syndrome
0.000 0.908 0.092
E24.1 Nelson's syndrome
0.000 0.908 0.092
J33.0 Polyp of nasal cavity
0.000 0.908 0.092
E26 Hyperaldosteronism
0.000 0.908 0.092
C82.3 Follicular lymphoma grade IIIa
0.000 0.910 0.090
E24.8 Other Cushing's syndrome
0.000 0.910 0.089
E53.9 Vitamin B deficiency, unspecified
0.000 0.911 0.089
C94 Other leukaemias of specified cell type
0.001 0.912 0.088
E23.2 Diabetes insipidus
0.000 0.912 0.088
E20 Hypoparathyroidism
0.000 0.913 0.087
C92.1 Chronic myeloid leukaemia
0.000 0.913 0.086
C83.1 Small cleaved cell (diffuse)
0.000 0.914 0.086
E29 Testicular dysfunction
0.000 0.914 0.086
C93 Monocytic leukaemia
0.001 0.914 0.085
E28.9 Ovarian dysfunction, unspecified
0.000 0.915 0.085
E28.8 Other ovarian dysfunction
0.000 0.915 0.085
E28.1 Androgen excess
0.000 0.915 0.085
E28.0 Oestrogen excess
0.000 0.915 0.085
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.085 0.915 0.000
C82.2 Large cell, follicular
0.000 0.916 0.084
C82.6 Cutaneous follicle centre lymphoma
0.000 0.917 0.082
C82.5 Diffuse follicle centre lymphoma
0.000 0.917 0.082
C88 Malignant immunoproliferative diseases
0.001 0.917 0.082
J33.1 Polypoid sinus degeneration
0.000 0.917 0.083
M07.36 Other psoriatic arthropathies (Lower leg)
0.082 0.917 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.082 0.918 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.919 0.081
E28.3 Primary ovarian failure
0.000 0.920 0.080
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.920 0.079
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.922 0.078
C82.4 Follicular lymphoma grade IIIb
0.000 0.922 0.078
C81.0 Lymphocytic predominance
0.000 0.922 0.077
E25.9 Adrenogenital disorder, unspecified
0.000 0.923 0.077
E25.8 Other adrenogenital disorders
0.000 0.923 0.077
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.923 0.077
C81.3 Lymphocytic depletion
0.000 0.923 0.077
C81.2 Mixed cellularity
0.000 0.923 0.077
C91 Lymphoid leukaemia
0.000 0.924 0.076
E30.9 Disorder of puberty, unspecified
0.000 0.924 0.076
E30.8 Other disorders of puberty
0.000 0.924 0.076
E30.1 Precocious puberty
0.000 0.924 0.076
E30.0 Delayed puberty
0.000 0.924 0.076
E31.9 Polyglandular dysfunction, unspecified
0.000 0.924 0.076
E31.8 Other polyglandular dysfunction
0.000 0.924 0.076
E31.1 Polyglandular hyperfunction
0.000 0.924 0.076
E31.0 Autoimmune polyglandular failure
0.000 0.924 0.076
E32.9 Disease of thymus, unspecified
0.000 0.924 0.076
E32.8 Other diseases of thymus
0.000 0.924 0.076
E32.1 Abscess of thymus
0.000 0.924 0.076
E32.0 Persistent hyperplasia of thymus
0.000 0.924 0.076
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.924 0.076
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.924 0.076
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.924 0.076
E23.7 Disorder of pituitary gland, unspecified
0.000 0.925 0.075
K60.1 Chronic anal fissure
0.000 0.926 0.074
C81.7 Other Hodgkin's disease
0.000 0.926 0.073
C82.0 Small cleaved cell, follicular
0.000 0.926 0.073
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.001 0.927 0.073
C86.4 Blastic NK-cell lymphoma
0.001 0.927 0.073
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.001 0.927 0.073
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.001 0.927 0.073
C86.1 Hepatosplenic T-cell lymphoma
0.001 0.927 0.073
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.001 0.927 0.073
C92.7 Other myeloid leukaemia
0.000 0.927 0.073
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.927 0.073
E23.1 Drug-induced hypopituitarism
0.000 0.927 0.073
C92.4 Acute promyelocytic leukaemia
0.000 0.928 0.071
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.071 0.928 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.929 0.071
K60.4 Rectal fistula
0.000 0.929 0.071
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.929 0.071
M07.38 Other psoriatic arthropathies (Other)
0.070 0.930 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.070 0.930 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.070 0.930 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.070 0.930 0.000
L43.3 Subacute (active) lichen planus
0.066 0.930 0.005
L43.2 Lichenoid drug reaction
0.066 0.930 0.005
L43.1 Bullous lichen planus
0.066 0.930 0.005
L43.0 Hypertrophic lichen planus
0.066 0.930 0.005
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.001 0.930 0.069
C96.8 Histiocytic sarcoma
0.001 0.930 0.069
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.001 0.930 0.069
C96.6 Unifocal Langerhans-cell histiocytosis
0.001 0.930 0.069
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.001 0.930 0.069
C96.4 Sarcoma of dendritic cells (accessory cells)
0.001 0.930 0.069
C96.3 True histiocytic lymphoma
0.001 0.930 0.069
C96.2 Malignant mast cell tumour
0.001 0.930 0.069
C96.1 Malignant histiocytosis
0.001 0.930 0.069
C96.0 Letterer-Siwe disease
0.001 0.930 0.069
K60.5 Anorectal fistula
0.000 0.930 0.070
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.001 0.930 0.069
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.001 0.930 0.069
C92.5 Acute myelomonocytic leukaemia
0.001 0.930 0.069
C92.3 Myeloid sarcoma
0.001 0.930 0.069
C92.2 Subacute myeloid leukaemia
0.001 0.930 0.069
E83.5 Disorders of calcium metabolism
0.069 0.930 0.000
C84.0 Mycosis fungoides
0.000 0.931 0.069
E22 Hyperfunction of pituitary gland
0.000 0.931 0.068
C83.0 Small cell (diffuse)
0.000 0.932 0.068
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.932 0.068
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.932 0.068
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.932 0.068
C84.3 Lymphoepithelioid lymphoma
0.000 0.932 0.068
C84.2 T-zone lymphoma
0.000 0.932 0.068
C84.1 Sezary's diease
0.000 0.932 0.068
C92.9 Myeloid leukaemia, unspecified
0.001 0.933 0.067
C95 Leukaemia of unspecified cell type
0.001 0.933 0.066
C91.9 Lymphoid leukaemia, unspecified
0.000 0.934 0.066
E26.9 Hyperaldosteronism, unspecified
0.000 0.934 0.066
E26.8 Other hyperaldosteronism
0.000 0.934 0.066
E26.1 Secondary hyperaldosteronism
0.000 0.934 0.066
L43.8 Other lichen planus
0.061 0.935 0.004
C84.5 Other and unspecified T-cell lymphomas
0.000 0.936 0.064
C84.4 Peripheral T-cell lymphoma
0.000 0.936 0.064
C94.7 Other specified leukaemias
0.001 0.936 0.063
C94.5 Acute myelofibrosis
0.001 0.936 0.063
C94.4 Acute panmyelosis
0.001 0.936 0.063
C94.3 Mast cell leukaemia
0.001 0.936 0.063
C94.2 Acute megakaryoblastic leukaemia
0.001 0.936 0.063
C94.1 Chronic erythraemia
0.001 0.936 0.063
C94.0 Acute erythraemia and erythroleukaemia
0.001 0.936 0.063
J45.0 Predominantly allergic asthma
0.000 0.937 0.063
E20.8 Other hypoparathyroidism
0.000 0.937 0.062
E20.1 Pseudohypoparathyroidism
0.000 0.937 0.062
E20.0 Idiopathic hypoparathyroidism
0.000 0.937 0.062
E23.6 Other disorders of pituitary gland
0.000 0.938 0.062

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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