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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3131019
log Bayes Factor = 41.6683
Chromosome 6   position 29,470,985  (GRCh37) Explore rs3131019 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.007 0.993
E10-E14 Diabetes mellitus
0.000 0.021 0.979
E10.4 With neurological complications
0.000 0.029 0.971
E10.2 With renal complications
0.000 0.041 0.959
E10.5 With peripheral circulatory complications
0.000 0.082 0.918
E14 Unspecified diabetes mellitus
0.000 0.090 0.910
E13 Other specified diabetes mellitus
0.000 0.104 0.896
E10.6 With other specified complications
0.000 0.130 0.870
E11 Non-insulin-dependent diabetes mellitus
0.000 0.173 0.827
E13.9 Without complications
0.000 0.178 0.822
E11.2 With renal complications
0.000 0.200 0.800
E14.5 With peripheral circulatory complications
0.000 0.207 0.793
E10.0 With coma
0.000 0.208 0.792
E10.8 With unspecified complications
0.000 0.253 0.746
E14.3 With ophthalmic complications
0.000 0.265 0.735
E14.4 With neurological complications
0.000 0.269 0.731
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.298 0.702
E13.3 With ophthalmic complications
0.000 0.308 0.692
E14.8 With unspecified complications
0.000 0.310 0.690
E14.6 With other specified complications
0.000 0.314 0.686
E14.1 With ketoacidosis
0.000 0.327 0.673
E11.5 With peripheral circulatory complications
0.000 0.329 0.671
K51 Ulcerative colitis
0.666 0.334 0.000
E11.1 With ketoacidosis
0.000 0.342 0.658
K51.9 Ulcerative colitis, unspecified
0.656 0.344 0.000
E14.2 Withrenal complications
0.000 0.345 0.655
E14.7 With multiple complications
0.000 0.347 0.652
E14.0 With coma
0.000 0.347 0.652
E13.8 With unspecified complications
0.000 0.357 0.642
E13.7 With multiple complications
0.000 0.357 0.642
E13.6 With other specified complications
0.000 0.357 0.642
E13.5 With peripheral circulatory complications
0.000 0.357 0.642
E13.4 With neurological complications
0.000 0.357 0.642
E13.2 With renal complications
0.000 0.357 0.642
E13.1 With ketoacidosis
0.000 0.357 0.642
E13.0 With coma
0.000 0.357 0.642
K50 Crohn's disease [regional enteritis]
0.639 0.361 0.000
K50-K52 Noninfective enteritis and colitis
0.635 0.365 0.000
K50.9 Crohn's disease, unspecified
0.634 0.366 0.000
K51.2 Ulcerative (chronic) proctitis
0.618 0.382 0.000
E11.0 With coma
0.000 0.382 0.618
K51.4 Pseudopolyposis of colon
0.612 0.388 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.390 0.610
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.397 0.603
K50.0 Crohn's disease of small intestine
0.601 0.399 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.402 0.598
E11.7 With multiple complications
0.000 0.407 0.593
E16.2 Hypoglycaemia, unspecified
0.000 0.412 0.588
K51.3 Ulcerative (chronic) rectosigmoiditis
0.585 0.415 0.000
E14.9 Without complications
0.000 0.427 0.573
E11.8 With unspecified complications
0.000 0.432 0.568
E50-E64 Other nutritional deficiencies
0.000 0.454 0.546
E11.6 With other specified complications
0.000 0.462 0.538
E16.1 Other hypoglycaemia
0.000 0.479 0.521
K51.5 Mucosal proctocolitis
0.512 0.488 0.000
K51.8 Other ulcerative colitis
0.509 0.491 0.000
E12.9 Without complications
0.000 0.497 0.503
E12.8 With unspecified complications
0.000 0.497 0.503
E12.7 With multiple complications
0.000 0.497 0.503
E12.6 With other specified complications
0.000 0.497 0.503
E12.5 With peripheral circulatory complications
0.000 0.497 0.503
E12.4 With neurological complications
0.000 0.497 0.503
E12.3 With ophthalmic complications
0.000 0.497 0.503
E12.2 With renal complications
0.000 0.497 0.503
E12.1 With ketoacidosis
0.000 0.497 0.503
E12.0 With coma
0.000 0.497 0.503
K50.8 Other Crohn's disease
0.502 0.498 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.484 0.516 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.540 0.460
E61 Deficiency of other nutrient elements
0.000 0.541 0.459
K51.1 Ulcerative (chronic) ileocolitis
0.453 0.547 0.000
E55 Vitamin D deficiency
0.000 0.564 0.436
E15 Nondiabetic hypoglycaemic coma
0.000 0.568 0.432
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.571 0.429
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.571 0.429
E16.4 Abnormal secretion of gastrin
0.000 0.571 0.429
E16.3 Increased secretion of glucagon
0.000 0.571 0.429
E11.4 With neurological complications
0.000 0.572 0.428
E51 Thiamine deficiency
0.000 0.574 0.426
E11.3 With ophthalmic complications
0.000 0.575 0.425
E56 Other vitamin deficiencies
0.000 0.589 0.411
K90 Intestinal malabsorption
0.002 0.595 0.402
E61.1 Iron deficiency
0.000 0.597 0.403
E53 Deficiency of other B group vitamins
0.000 0.598 0.402
K50.1 Crohn's disease of large intestine
0.391 0.609 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.609 0.391
E63 Other nutritional deficiencies
0.000 0.609 0.391
E50 Vitamin A deficiency
0.000 0.609 0.391
E60 Dietary zinc deficiency
0.000 0.609 0.391
E59 Dietary selenium deficiency
0.000 0.609 0.391
E54 Ascorbic acid deficiency
0.000 0.609 0.391
E52 Niacin deficiency [pellagra]
0.000 0.609 0.391
E40-E46 Malnutrition
0.000 0.633 0.367
E58 Dietary calcium deficiency
0.000 0.638 0.362
E20-E35 Disorders of other endocrine glands
0.000 0.639 0.361
E55.9 Vitamin D deficiency, unspecified
0.000 0.643 0.357
E00-E07 Disorders of thyroid gland
0.000 0.653 0.347
E51.2 Wernicke's encephalopathy
0.000 0.660 0.340
E24 Cushing's syndrome
0.000 0.664 0.336
E61.9 Deficiency of nutrient element, unspecified
0.000 0.670 0.329
E61.8 Deficiency of other specified nutrient elements
0.000 0.670 0.329
E61.7 Deficiency of multiple nutrient elements
0.000 0.670 0.329
E61.6 Vanadium deficiency
0.000 0.670 0.329
E61.5 Molybdenum deficiency
0.000 0.670 0.329
E61.4 Chromium deficiency
0.000 0.670 0.329
E61.3 Manganese deficiency
0.000 0.670 0.329
E61.0 Copper deficiency
0.000 0.670 0.329
K90.9 Intestinal malabsorption, unspecified
0.001 0.673 0.326
E53.9 Vitamin B deficiency, unspecified
0.000 0.679 0.321
E61.2 Magnesium deficiency
0.000 0.684 0.316
E56.1 Deficiency of vitamin K
0.000 0.685 0.315
E55.0 Rickets, active
0.000 0.687 0.312
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.690 0.310
E51.9 Thiamine deficiency, unspecified
0.000 0.694 0.305
E51.8 Other manifestations of thiamine deficiency
0.000 0.694 0.305
E51.1 Beriberi
0.000 0.694 0.305
E24.9 Cushing's syndrome, unspecified
0.000 0.701 0.299
E07 Other disorders of thyroid
0.000 0.702 0.298
E56.9 Vitamin deficiency, unspecified
0.000 0.705 0.295
E56.8 Deficiency of other vitamins
0.000 0.705 0.295
E56.0 Deficiency of vitamin E
0.000 0.705 0.295
E23 Hypofunction and other disorders of pituitary gland
0.000 0.706 0.294
K90.8 Other intestinal malabsorption
0.001 0.708 0.290
K90.3 Pancreatic steatorrhoea
0.002 0.710 0.289
K90.2 Blind loop syndrome, not elsewhere classified
0.002 0.710 0.289
K90.1 Tropical sprue
0.002 0.710 0.289
E53.1 Pyridoxine deficiency
0.000 0.712 0.288
E53.0 Riboflavin deficiency
0.000 0.712 0.288
E24.0 Pituitary-dependent Cushing's disease
0.000 0.712 0.288
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.716 0.284
E50.9 Vitamin A deficiency, unspecified
0.000 0.719 0.281
E50.8 Other manifestations of vitamin A deficiency
0.000 0.719 0.281
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.719 0.281
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.719 0.281
E50.5 Vitamin A deficiency with night blindness
0.000 0.719 0.281
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.719 0.281
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.719 0.281
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.719 0.281
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.719 0.281
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.719 0.281
E63.9 Nutritional deficiency, unspecified
0.000 0.719 0.281
E63.8 Other specified nutritional deficiencies
0.000 0.719 0.281
E63.1 Imbalance of constituents of food intake
0.000 0.719 0.281
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.719 0.281
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.719 0.281
E64.8 Sequelae of other nutritional deficiencies
0.000 0.719 0.281
E64.3 Sequelae of rickets
0.000 0.719 0.281
E64.2 Sequelae of vitamin C deficiency
0.000 0.719 0.281
E64.1 Sequelae of vitamin A deficiency
0.000 0.719 0.281
E64.0 Sequelae of protein-energy malnutrition
0.000 0.719 0.281
E11.9 Without complications
0.000 0.724 0.276
E28 Ovarian dysfunction
0.000 0.728 0.272
E20 Hypoparathyroidism
0.000 0.730 0.270
N84.1 Polyp of cervix uteri
0.265 0.735 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.735 0.265
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.737 0.263
E45 Retarded development following protein-energy malnutrition
0.000 0.737 0.263
E43 Unspecified severe protein-energy malnutrition
0.000 0.737 0.263
E42 Marasmic kwashiorkor
0.000 0.737 0.263
E41 Nutritional marasmus
0.000 0.737 0.263
E40 Kwashiorkor
0.000 0.737 0.263
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.741 0.259
E32 Diseases of thymus
0.000 0.741 0.259
E30 Disorders of puberty, not elsewhere classified
0.000 0.741 0.259
E25 Adrenogenital disorders
0.000 0.741 0.259
E07.8 Other specified disorders of thyroid
0.000 0.741 0.259
E53.8 Deficiency of other specified B group vitamins
0.000 0.744 0.256
E05.9 Thyrotoxicosis, unspecified
0.000 0.748 0.252
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.751 0.249
E00 Congenital iodine-deficiency syndrome
0.000 0.751 0.249
E23.0 Hypopituitarism
0.000 0.754 0.246
E24.2 Drug-induced Cushing's syndrome
0.000 0.757 0.243
E31 Polyglandular dysfunction
0.000 0.758 0.242
E24.8 Other Cushing's syndrome
0.000 0.759 0.241
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.759 0.241
E24.3 Ectopic ACTH syndrome
0.000 0.759 0.241
E24.1 Nelson's syndrome
0.000 0.759 0.241
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.765 0.235
E65-E68 Obesity and other hyperalimentation
0.000 0.769 0.231
E23.2 Diabetes insipidus
0.000 0.769 0.231
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.774 0.226
E07.9 Disorder of thyroid, unspecified
0.000 0.776 0.224
E05.5 Thyroid crisis or storm
0.000 0.777 0.223
E05.4 Thyrotoxicosis factitia
0.000 0.777 0.223
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.777 0.223
E28.3 Primary ovarian failure
0.000 0.778 0.222
E23.7 Disorder of pituitary gland, unspecified
0.000 0.779 0.221
E05.8 Other thyrotoxicosis
0.000 0.780 0.220
E06 Thyroiditis
0.000 0.785 0.215
E07.1 Dyshormogenetic goitre
0.000 0.786 0.214
E07.0 Hypersecretion of calcitonin
0.000 0.786 0.214
E29 Testicular dysfunction
0.000 0.788 0.212
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.789 0.211
E23.1 Drug-induced hypopituitarism
0.000 0.789 0.211
E21.3 Hyperparathyroidism, unspecified
0.000 0.792 0.208
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.002 0.792 0.206
E20.9 Hypoparathyroidism, unspecified
0.000 0.796 0.204
E26 Hyperaldosteronism
0.000 0.798 0.202
E34 Other endocrine disorders
0.000 0.800 0.200
E28.9 Ovarian dysfunction, unspecified
0.000 0.804 0.195
E28.8 Other ovarian dysfunction
0.000 0.804 0.195
E28.1 Androgen excess
0.000 0.804 0.195
E28.0 Oestrogen excess
0.000 0.804 0.195
E20.8 Other hypoparathyroidism
0.000 0.806 0.194
E20.1 Pseudohypoparathyroidism
0.000 0.806 0.194
E20.0 Idiopathic hypoparathyroidism
0.000 0.806 0.194
E46 Unspecified protein-energy malnutrition
0.000 0.807 0.192
E21.0 Primary hyperparathyroidism
0.000 0.808 0.192
E21.4 Other specified disorders of parathyroid gland
0.000 0.810 0.190
E44.1 Mild protein-energy malnutrition
0.000 0.811 0.189
E44.0 Moderate protein-energy malnutrition
0.000 0.811 0.189
E22 Hyperfunction of pituitary gland
0.000 0.812 0.188
E25.9 Adrenogenital disorder, unspecified
0.000 0.814 0.186
E25.8 Other adrenogenital disorders
0.000 0.814 0.186
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.814 0.186
E30.9 Disorder of puberty, unspecified
0.000 0.814 0.186
E30.8 Other disorders of puberty
0.000 0.814 0.186
E30.1 Precocious puberty
0.000 0.814 0.186
E30.0 Delayed puberty
0.000 0.814 0.186
E32.9 Disease of thymus, unspecified
0.000 0.814 0.186
E32.8 Other diseases of thymus
0.000 0.814 0.186
E32.1 Abscess of thymus
0.000 0.814 0.186
E32.0 Persistent hyperplasia of thymus
0.000 0.814 0.186
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.814 0.186
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.814 0.186
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.814 0.186
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.815 0.185
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.816 0.184
E06.9 Thyroiditis, unspecified
0.000 0.817 0.183
E21.2 Other hyperparathyroidism
0.000 0.818 0.182
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.821 0.179
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.821 0.179
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.821 0.179
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.821 0.179
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.821 0.179
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.821 0.179
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.821 0.179
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.821 0.179
E28.2 Polycystic ovarian syndrome
0.000 0.824 0.176
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.825 0.175
E31.9 Polyglandular dysfunction, unspecified
0.000 0.826 0.173
E31.8 Other polyglandular dysfunction
0.000 0.826 0.173
E31.1 Polyglandular hyperfunction
0.000 0.826 0.173
E23.6 Other disorders of pituitary gland
0.000 0.833 0.166
E67 Other hyperalimentation
0.000 0.834 0.166
E68 Sequelae of hyperalimentation
0.000 0.834 0.166
E34.8 Other specified endocrine disorders
0.000 0.838 0.162
E27 Other disorders of adrenal gland
0.000 0.841 0.159
E31.0 Autoimmune polyglandular failure
0.000 0.844 0.156
E06.4 Drug-induced thyroiditis
0.000 0.846 0.154
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.846 0.154
E06.1 Subacute thyroiditis
0.000 0.846 0.154
E06.0 Acute thyroiditis
0.000 0.846 0.154
E29.9 Testicular dysfunction, unspecified
0.000 0.848 0.152
E29.8 Other testicular dysfunction
0.000 0.848 0.152
E29.0 Testicular hyperfunction
0.000 0.848 0.152
E27.1 Primary adrenocortical insufficiency
0.000 0.853 0.147
E26.8 Other hyperaldosteronism
0.000 0.855 0.145
E26.1 Secondary hyperaldosteronism
0.000 0.855 0.145
E26.9 Hyperaldosteronism, unspecified
0.000 0.855 0.144
E34.5 Androgen resistance syndrome
0.000 0.856 0.144
E34.4 Constitutional tall stature
0.000 0.856 0.144
E34.3 Short stature, not elsewhere classified
0.000 0.856 0.144
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.856 0.144
E34.1 Other hypersecretion of intestinal hormones
0.000 0.856 0.144
E22.0 Acromegaly and pituitary gigantism
0.000 0.858 0.142
E65 Localised adiposity
0.000 0.859 0.141
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.865 0.135
E22.8 Other hyperfunction of pituitary gland
0.000 0.865 0.135
E03 Other hypothyroidism
0.000 0.871 0.129
E06.5 Other chronic thyroiditis
0.000 0.880 0.119
E67.8 Other specified hyperalimentation
0.000 0.881 0.119
E67.3 Hypervitaminosis D
0.000 0.881 0.119
E67.2 Megavitamin-B6 syndrome
0.000 0.881 0.119
E67.1 Hypercarotenaemia
0.000 0.881 0.119
E67.0 Hypervitaminosis A
0.000 0.881 0.119
E22.1 Hyperprolactinaemia
0.000 0.884 0.116
E27.5 Adrenomedullary hyperfunction
0.000 0.885 0.114
E27.0 Other adrenocortical overactivity
0.000 0.885 0.114
E83 Disorders of mineral metabolism
0.110 0.887 0.003
E27.8 Other specified disorders of adrenal gland
0.000 0.891 0.109
E34.9 Endocrine disorder, unspecified
0.000 0.894 0.106
E29.1 Testicular hypofunction
0.000 0.895 0.105
E06.3 Autoimmune thyroiditis
0.000 0.900 0.100
E03.8 Other specified hypothyroidism
0.000 0.900 0.100
E34.0 Carcinoid syndrome
0.000 0.901 0.099
E03.1 Congenital hypothyroidism without goitre
0.000 0.901 0.099
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.903 0.097
E03.5 Myxoedema coma
0.000 0.907 0.093
E03.4 Atrophy of thyroid (acquired)
0.000 0.907 0.093
E03.3 Postinfectious hypothyroidism
0.000 0.907 0.093
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.907 0.093
E26.0 Primary hyperaldosteronism
0.001 0.911 0.088
E27.9 Disorder of adrenal gland, unspecified
0.000 0.915 0.084
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.918 0.081
E83.8 Other disorders of mineral metabolism
0.079 0.918 0.002
E83.2 Disorders of zinc metabolism
0.079 0.918 0.002
E83.0 Disorders of copper metabolism
0.079 0.918 0.002
E83.3 Disorders of phosphorus metabolism
0.079 0.920 0.001
E83.9 Disorder of mineral metabolism, unspecified
0.074 0.923 0.002
E27.2 Addisonian crisis
0.000 0.930 0.070
K52 Other non-infective gastro-enteritis and colitis
0.063 0.936 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.937 0.063
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.941 0.058
Z99.1 Dependence on respirator
0.000 0.942 0.058
E04 Other non-toxic goitre
0.000 0.945 0.055
K52.0 Gastro-enteritis and colitis due to radiation
0.051 0.949 0.000
E83.4 Disorders of magnesium metabolism
0.049 0.950 0.001
J38.3 Other diseases of vocal cords
0.043 0.957 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.958 0.042
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.042 0.958 0.000
J38.7 Other diseases of larynx
0.042 0.958 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.041 0.958 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.959 0.041
E04.8 Other specified non-toxic goitre
0.000 0.960 0.040
J38.4 Oedema of larynx
0.039 0.961 0.000
K52.3 Indeterminate colitis
0.039 0.961 0.000
J38.5 Laryngeal spasm
0.036 0.964 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.035 0.965 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.965 0.035
K43 Ventral hernia
0.035 0.965 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.966 0.034
E66 Obesity
0.000 0.966 0.034
K52.1 Toxic gastro-enteritis and colitis
0.034 0.966 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.034 0.966 0.000
J38.2 Nodules of vocal cords
0.033 0.967 0.000
K90-K93 Other diseases of the digestive system
0.010 0.967 0.023
Z99.8 Dependence on other enabling machines and devices
0.000 0.967 0.033
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.968 0.032
F45.8 Other somatoform disorders
0.000 0.968 0.032
J38.0 Paralysis of vocal cords and larynx
0.030 0.970 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.030 0.970 0.000
K41 Femoral hernia
0.030 0.970 0.000
K40-K46 Hernia
0.029 0.971 0.000
E83.5 Disorders of calcium metabolism
0.029 0.971 0.000
L40.9 Psoriasis, unspecified
0.000 0.971 0.029
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.029 0.971 0.000
J38.6 Stenosis of larynx
0.028 0.972 0.000
K40 Inguinal hernia
0.028 0.972 0.000
E70-E90 Metabolic disorders
0.001 0.972 0.027
E73.9 Lactose intolerance, unspecified
0.000 0.972 0.028
E73 Lactose intolerance
0.000 0.973 0.027
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.975 0.025
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.975 0.025
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.975 0.025
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.975 0.025
J38.1 Polyp of vocal cord and larynx
0.025 0.975 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.975 0.025
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.025 0.975 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.025 0.975 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.025 0.975 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.025 0.975 0.000
K43.4 Parastomal hernia with gangrene
0.025 0.975 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.025 0.975 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.025 0.975 0.000
K43.1 Ventral hernia with gangrene
0.025 0.975 0.000
E66.1 Drug-induced obesity
0.000 0.975 0.024
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.976 0.024
K93 Disorders of other digestive organs in diseases classified elsewhere
0.007 0.976 0.017
F45 Somatoform disorders
0.000 0.976 0.024
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.024 0.976 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.977 0.023
Z99.4 Dependence on artificial heart
0.000 0.977 0.023
Z99.0 Dependence on aspirator
0.000 0.977 0.023
N99.3 Prolapse of vaginal vault after hysterectomy
0.023 0.977 0.000
E66.0 Obesity due to excess calories
0.000 0.977 0.023
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.023 0.977 0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.022 0.978 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.978 0.021
K46 Unspecified abdominal hernia
0.022 0.978 0.000
K41.1 Bilateral femoral hernia, with gangrene
0.021 0.978 0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.021 0.978 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.979 0.021
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.979 0.021
E84 Cystic fibrosis
0.000 0.979 0.021
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.021 0.979 0.000
F45.9 Somatoform disorder, unspecified
0.000 0.979 0.021
N99.5 Malfunction of external stoma of urinary tract
0.021 0.979 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.020 0.980 0.000
E77 Disorders of glycoprotein metabolism
0.001 0.980 0.020
E76 Disorders of glycosaminoglycan metabolism
0.001 0.980 0.020
E72 Other disorders of amino-acid metabolism
0.001 0.980 0.020
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.980 0.020
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.980 0.020
N99.8 Other postprocedural disorders of genito-urinary system
0.020 0.980 0.000
E73.8 Other lactose intolerance
0.000 0.980 0.019
E73.1 Secondary lactase deficiency
0.000 0.980 0.019
E73.0 Congenital lactase deficiency
0.000 0.980 0.019
E70 Disorders of aromatic amino-acid metabolism
0.001 0.980 0.019
F45.2 Hypochondriacal disorder
0.000 0.980 0.019
F45.0 Somatisation disorder
0.000 0.981 0.019
L40 Psoriasis
0.000 0.981 0.019
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.982 0.018
L40.5 Arthropathic psoriasis
0.000 0.982 0.018
Z04.8 Examination and observation for other specified reasons
0.018 0.982 0.000
Chapter XI Diseases of the digestive system
0.018 0.982 0.000
E88 Other metabolic disorders
0.000 0.982 0.017
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.017 0.982 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.005 0.982 0.012
K93.1 Megacolon in Chagas' disease
0.005 0.982 0.012
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.005 0.982 0.012
N99.2 Postprocedural adhesions of vagina
0.017 0.982 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.983 0.017
F45.1 Undifferentiated somatoform disorder
0.000 0.983 0.017
E85 Amyloidosis
0.001 0.983 0.017
F45.3 Somatoform autonomic dysfunction
0.000 0.983 0.017
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.983 0.016
E75.5 Other lipid storage disorders
0.000 0.983 0.016
F45.4 Persistent somatoform pain disorder
0.000 0.983 0.017
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.017 0.983 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.983 0.016
E74.0 Glycogen storage disease
0.000 0.984 0.016
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.984 0.016
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.984 0.016
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.984 0.016
E74.2 Disorders of galactose metabolism
0.000 0.984 0.016
E74.1 Disorders of fructose metabolism
0.000 0.984 0.016
K46.1 Unspecified abdominal hernia with gangrene
0.016 0.984 0.000
L40.1 Generalised pustular psoriasis
0.000 0.984 0.016
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.016 0.984 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.984 0.016
E75.6 Lipid storage disorder, unspecified
0.000 0.984 0.015
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.984 0.015
E75.3 Sphingolipidosis, unspecified
0.000 0.984 0.015
E75.2 Other sphingolipidosis
0.000 0.984 0.015
E75.1 Other gangliosidosis
0.000 0.984 0.015
E75.0 GM2 gangliosidosis
0.000 0.984 0.015
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.984 0.015
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.984 0.015
E79.1 Lesch-Nyhan syndrome
0.000 0.984 0.015
E84.8 Cystic fibrosis with other manifestations
0.000 0.985 0.015
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.985 0.015
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.985 0.015
N84 Polyp of female genital tract
0.015 0.985 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.015 0.985 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.985 0.015
K45 Other abdominal hernia
0.015 0.985 0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified
0.015 0.985 0.000
E71.3 Disorders of fatty-acid metabolism
0.001 0.985 0.014
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.985 0.014
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.985 0.014
E71.0 Maple-syrup-urine disease
0.001 0.985 0.014
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.985 0.014
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.985 0.014
E72.5 Disorders of glycine metabolism
0.001 0.985 0.014
E72.4 Disorders of ornithine metabolism
0.001 0.985 0.014
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.985 0.014
E72.2 Disorders of urea cycle metabolism
0.001 0.985 0.014
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.985 0.014
E72.0 Disorders of amino-acid transport
0.001 0.985 0.014
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.985 0.014
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.985 0.014
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.985 0.014
E76.2 Other mucopolysaccharidoses
0.001 0.985 0.014
E76.1 Mucopolysaccharidosis, type II
0.001 0.985 0.014
E76.0 Mucopolysaccharidosis, type I
0.001 0.985 0.014
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.985 0.014
E77.8 Other disorders of glycoprotein metabolism
0.001 0.985 0.014
E77.1 Defects in glycoprotein degradation
0.001 0.985 0.014
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.985 0.014
E85.4 Organ-limited amyloidosis
0.000 0.985 0.014
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.986 0.014
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.986 0.014
E70.2 Disorders of tyrosine metabolism
0.001 0.986 0.014
E70.1 Other hyperphenylalaninaemias
0.001 0.986 0.014
E70.0 Classical phenylketonuria
0.001 0.986 0.014
N99.1 Postprocedural urethral stricture
0.014 0.986 0.000
E70.3 Albinism
0.001 0.986 0.013
L40.2 Acrodermatitis continua
0.000 0.986 0.014
E88.2 Lipomatosis, not elsewhere classified
0.000 0.986 0.014
K59.8 Other specified functional intestinal disorders
0.014 0.986 0.000
L43.9 Lichen planus, unspecified
0.000 0.987 0.013
L43 Lichen planus
0.000 0.987 0.013
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.987 0.013
L40-L45 Papulosquamous disorders
0.000 0.987 0.013
E66.8 Other obesity
0.000 0.987 0.013
E88.9 Metabolic disorder, unspecified
0.000 0.987 0.013
E04.2 Non-toxic multinodular goitre
0.000 0.987 0.013
M31.6 Other giant cell arteritis
0.000 0.987 0.013
K65-K67 Diseases of peritoneum
0.013 0.987 0.000
Q23.1 Congenital insufficiency of aortic valve
0.013 0.987 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.987 0.012
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.987 0.012
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.987 0.012
N84.9 Polyp of female genital tract, unspecified
0.012 0.988 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.988 0.012
L40.4 Guttate psoriasis
0.000 0.988 0.012
Z99.2 Dependence on renal dialysis
0.000 0.988 0.012
E85.8 Other amyloidosis
0.001 0.988 0.011
Z99.3 Dependence on wheelchair
0.000 0.988 0.012
E88.3 Tumour lysis syndrome
0.000 0.988 0.011
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.988 0.012
K65 Peritonitis
0.012 0.988 0.000
K65.9 Peritonitis, unspecified
0.011 0.989 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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