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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3131083
log Bayes Factor = 54.2803
Chromosome 6   position 29,039,977  (GRCh37) Explore rs3131083 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.009 0.991
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.029 0.971
E10.2 With renal complications
0.000 0.044 0.956
E10.1 With ketoacidosis
0.000 0.123 0.877
E10.4 With neurological complications
0.000 0.133 0.867
E05.8 Other thyrotoxicosis
0.000 0.196 0.804
E16.1 Other hypoglycaemia
0.000 0.205 0.795
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.215 0.785
E13 Other specified diabetes mellitus
0.000 0.228 0.772
E40-E46 Malnutrition
0.000 0.239 0.761
E10.7 With multiple complications
0.000 0.245 0.754
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E10.0 With coma
0.000 0.288 0.712
E10.6 With other specified complications
0.000 0.343 0.657
E14 Unspecified diabetes mellitus
0.000 0.354 0.646
E07 Other disorders of thyroid
0.000 0.357 0.643
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.358 0.642
E10.5 With peripheral circulatory complications
0.000 0.360 0.640
E06 Thyroiditis
0.000 0.362 0.638
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.621 0.379 0.000
E13.9 Without complications
0.000 0.381 0.619
E46 Unspecified protein-energy malnutrition
0.000 0.409 0.591
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.412 0.588
E03 Other hypothyroidism
0.000 0.419 0.581
E13.8 With unspecified complications
0.000 0.447 0.553
E13.7 With multiple complications
0.000 0.447 0.553
E13.6 With other specified complications
0.000 0.447 0.553
E13.5 With peripheral circulatory complications
0.000 0.447 0.553
E13.4 With neurological complications
0.000 0.447 0.553
E13.2 With renal complications
0.000 0.447 0.553
E13.1 With ketoacidosis
0.000 0.447 0.553
E13.0 With coma
0.000 0.447 0.553
E14.3 With ophthalmic complications
0.000 0.451 0.549
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.454 0.546
E45 Retarded development following protein-energy malnutrition
0.000 0.454 0.546
E43 Unspecified severe protein-energy malnutrition
0.000 0.454 0.546
E42 Marasmic kwashiorkor
0.000 0.454 0.546
E41 Nutritional marasmus
0.000 0.454 0.546
E40 Kwashiorkor
0.000 0.454 0.546
E13.3 With ophthalmic complications
0.000 0.460 0.540
E06.9 Thyroiditis, unspecified
0.000 0.469 0.530
E10.8 With unspecified complications
0.000 0.471 0.529
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.512
E14.1 With ketoacidosis
0.000 0.488 0.512
E07.8 Other specified disorders of thyroid
0.000 0.491 0.509
E14.8 With unspecified complications
0.000 0.506 0.494
E06.1 Subacute thyroiditis
0.000 0.517 0.483
E14.6 With other specified complications
0.000 0.520 0.480
E14.4 With neurological complications
0.000 0.528 0.472
K90 Intestinal malabsorption
0.000 0.532 0.468
E14.7 With multiple complications
0.000 0.536 0.463
E07.1 Dyshormogenetic goitre
0.000 0.539 0.461
E07.0 Hypersecretion of calcitonin
0.000 0.539 0.461
E06.4 Drug-induced thyroiditis
0.000 0.542 0.457
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.542 0.457
E06.0 Acute thyroiditis
0.000 0.542 0.457
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.544 0.455
E14.5 With peripheral circulatory complications
0.000 0.556 0.444
E06.5 Other chronic thyroiditis
0.000 0.556 0.443
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.562 0.438
E14.0 With coma
0.000 0.564 0.436
E14.2 Withrenal complications
0.000 0.572 0.428
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.572 0.428
E03.5 Myxoedema coma
0.000 0.583 0.416
E03.4 Atrophy of thyroid (acquired)
0.000 0.583 0.416
E03.3 Postinfectious hypothyroidism
0.000 0.583 0.416
E03.1 Congenital hypothyroidism without goitre
0.000 0.595 0.405
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.606 0.394
E44.1 Mild protein-energy malnutrition
0.000 0.608 0.391
E44.0 Moderate protein-energy malnutrition
0.000 0.608 0.391
E65-E68 Obesity and other hyperalimentation
0.000 0.638 0.362
E03.8 Other specified hypothyroidism
0.000 0.639 0.361
E50-E64 Other nutritional deficiencies
0.000 0.653 0.347
K90.3 Pancreatic steatorrhoea
0.000 0.665 0.335
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.665 0.335
K90.1 Tropical sprue
0.000 0.665 0.335
K90.8 Other intestinal malabsorption
0.000 0.673 0.327
E03.9 Hypothyroidism, unspecified
0.000 0.677 0.323
E07.9 Disorder of thyroid, unspecified
0.000 0.702 0.298
K90.9 Intestinal malabsorption, unspecified
0.000 0.727 0.273
E67 Other hyperalimentation
0.000 0.741 0.259
E68 Sequelae of hyperalimentation
0.000 0.741 0.259
E51 Thiamine deficiency
0.000 0.751 0.249
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.751 0.249
E50 Vitamin A deficiency
0.000 0.751 0.249
E60 Dietary zinc deficiency
0.000 0.751 0.249
E59 Dietary selenium deficiency
0.000 0.751 0.249
E52 Niacin deficiency [pellagra]
0.000 0.751 0.249
E54 Ascorbic acid deficiency
0.000 0.756 0.244
E56 Other vitamin deficiencies
0.000 0.763 0.236
E20-E35 Disorders of other endocrine glands
0.000 0.768 0.232
E55 Vitamin D deficiency
0.000 0.768 0.232
E58 Dietary calcium deficiency
0.000 0.770 0.229
E63 Other nutritional deficiencies
0.000 0.774 0.226
M45.X9 Ankylosing spondylitis (Site unspecified)
0.222 0.778 0.000
E65 Localised adiposity
0.000 0.779 0.221
E24 Cushing's syndrome
0.000 0.785 0.215
E61 Deficiency of other nutrient elements
0.000 0.790 0.210
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.793 0.207
E21.3 Hyperparathyroidism, unspecified
0.000 0.803 0.197
R31 Unspecified haematuria
0.194 0.806 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.808 0.192
E24.9 Cushing's syndrome, unspecified
0.000 0.813 0.187
E67.8 Other specified hyperalimentation
0.000 0.814 0.186
E67.3 Hypervitaminosis D
0.000 0.814 0.186
E67.2 Megavitamin-B6 syndrome
0.000 0.814 0.186
E67.1 Hypercarotenaemia
0.000 0.814 0.186
E67.0 Hypervitaminosis A
0.000 0.814 0.186
E53 Deficiency of other B group vitamins
0.000 0.816 0.184
E24.0 Pituitary-dependent Cushing's disease
0.000 0.819 0.181
E51.2 Wernicke's encephalopathy
0.000 0.821 0.179
E51.9 Thiamine deficiency, unspecified
0.000 0.821 0.179
E51.8 Other manifestations of thiamine deficiency
0.000 0.821 0.179
E51.1 Beriberi
0.000 0.821 0.179
E50.9 Vitamin A deficiency, unspecified
0.000 0.821 0.179
E50.8 Other manifestations of vitamin A deficiency
0.000 0.821 0.179
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.821 0.179
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.821 0.179
E50.5 Vitamin A deficiency with night blindness
0.000 0.821 0.179
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.821 0.179
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.821 0.179
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.821 0.179
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.821 0.179
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.821 0.179
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.821 0.179
E64.8 Sequelae of other nutritional deficiencies
0.000 0.821 0.179
E64.3 Sequelae of rickets
0.000 0.821 0.179
E64.2 Sequelae of vitamin C deficiency
0.000 0.821 0.179
E64.1 Sequelae of vitamin A deficiency
0.000 0.821 0.179
E64.0 Sequelae of protein-energy malnutrition
0.000 0.821 0.179
E11.6 With other specified complications
0.000 0.826 0.174
E06.3 Autoimmune thyroiditis
0.000 0.828 0.172
E24.2 Drug-induced Cushing's syndrome
0.000 0.830 0.170
E56.9 Vitamin deficiency, unspecified
0.000 0.830 0.170
E56.8 Deficiency of other vitamins
0.000 0.830 0.170
E56.0 Deficiency of vitamin E
0.000 0.830 0.170
E20 Hypoparathyroidism
0.000 0.831 0.168
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.833 0.167
E32 Diseases of thymus
0.000 0.833 0.167
E30 Disorders of puberty, not elsewhere classified
0.000 0.833 0.167
E55.0 Rickets, active
0.000 0.833 0.166
E25 Adrenogenital disorders
0.000 0.837 0.162
E21.4 Other specified disorders of parathyroid gland
0.000 0.838 0.162
E63.8 Other specified nutritional deficiencies
0.000 0.838 0.162
E63.1 Imbalance of constituents of food intake
0.000 0.838 0.162
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.838 0.162
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.839 0.161
E31 Polyglandular dysfunction
0.000 0.840 0.160
E56.1 Deficiency of vitamin K
0.000 0.842 0.157
E28 Ovarian dysfunction
0.000 0.843 0.157
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.844 0.156
E24.8 Other Cushing's syndrome
0.000 0.845 0.155
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.845 0.155
E24.3 Ectopic ACTH syndrome
0.000 0.845 0.155
E24.1 Nelson's syndrome
0.000 0.845 0.155
E61.9 Deficiency of nutrient element, unspecified
0.000 0.849 0.150
E61.8 Deficiency of other specified nutrient elements
0.000 0.849 0.150
E61.7 Deficiency of multiple nutrient elements
0.000 0.849 0.150
E61.6 Vanadium deficiency
0.000 0.849 0.150
E61.5 Molybdenum deficiency
0.000 0.849 0.150
E61.4 Chromium deficiency
0.000 0.849 0.150
E61.3 Manganese deficiency
0.000 0.849 0.150
E61.0 Copper deficiency
0.000 0.849 0.150
E21.2 Other hyperparathyroidism
0.000 0.850 0.150
E55.9 Vitamin D deficiency, unspecified
0.000 0.851 0.149
E11.1 With ketoacidosis
0.000 0.852 0.148
E11.0 With coma
0.000 0.853 0.147
E11.2 With renal complications
0.000 0.853 0.147
E53.9 Vitamin B deficiency, unspecified
0.000 0.857 0.143
E83 Disorders of mineral metabolism
0.134 0.859 0.007
E63.9 Nutritional deficiency, unspecified
0.000 0.861 0.138
E11.7 With multiple complications
0.000 0.862 0.138
E61.1 Iron deficiency
0.000 0.863 0.137
E29 Testicular dysfunction
0.000 0.863 0.137
E34 Other endocrine disorders
0.000 0.866 0.134
E53.1 Pyridoxine deficiency
0.000 0.868 0.132
E53.0 Riboflavin deficiency
0.000 0.868 0.132
E61.2 Magnesium deficiency
0.000 0.871 0.129
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.877 0.123
E20.9 Hypoparathyroidism, unspecified
0.000 0.877 0.123
E20.8 Other hypoparathyroidism
0.000 0.879 0.121
E20.1 Pseudohypoparathyroidism
0.000 0.879 0.121
E20.0 Idiopathic hypoparathyroidism
0.000 0.879 0.121
E30.9 Disorder of puberty, unspecified
0.000 0.880 0.120
E30.8 Other disorders of puberty
0.000 0.880 0.120
E30.1 Precocious puberty
0.000 0.880 0.120
E30.0 Delayed puberty
0.000 0.880 0.120
E32.9 Disease of thymus, unspecified
0.000 0.880 0.120
E32.8 Other diseases of thymus
0.000 0.880 0.120
E32.1 Abscess of thymus
0.000 0.880 0.120
E32.0 Persistent hyperplasia of thymus
0.000 0.880 0.120
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.880 0.120
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.880 0.120
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.880 0.120
I83 Varicose veins of lower extremities
0.117 0.883 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.883 0.117
E25.8 Other adrenogenital disorders
0.000 0.883 0.117
E31.9 Polyglandular dysfunction, unspecified
0.000 0.885 0.115
E31.8 Other polyglandular dysfunction
0.000 0.885 0.115
E31.1 Polyglandular hyperfunction
0.000 0.885 0.115
E28.2 Polycystic ovarian syndrome
0.000 0.886 0.114
E11.8 With unspecified complications
0.000 0.886 0.114
E83.3 Disorders of phosphorus metabolism
0.112 0.886 0.002
C15-C26 Malignant neoplasms of digestive organs
0.000 0.887 0.113
C20 Malignant neoplasm of rectum
0.000 0.887 0.113
E28.9 Ovarian dysfunction, unspecified
0.000 0.887 0.113
E28.8 Other ovarian dysfunction
0.000 0.887 0.113
E28.1 Androgen excess
0.000 0.887 0.113
E28.0 Oestrogen excess
0.000 0.887 0.113
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.888 0.112
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.888 0.112
E26 Hyperaldosteronism
0.000 0.889 0.110
C15 Malignant neoplasm of oesophagus
0.000 0.890 0.110
E31.0 Autoimmune polyglandular failure
0.000 0.892 0.107
E83.8 Other disorders of mineral metabolism
0.096 0.899 0.005
E83.2 Disorders of zinc metabolism
0.096 0.899 0.005
E83.0 Disorders of copper metabolism
0.096 0.899 0.005
E28.3 Primary ovarian failure
0.000 0.899 0.101
E29.9 Testicular dysfunction, unspecified
0.000 0.899 0.101
C15.5 Lower third of oesophagus
0.000 0.900 0.100
E83.9 Disorder of mineral metabolism, unspecified
0.095 0.900 0.005
C25 Malignant neoplasm of pancreas
0.000 0.900 0.100
E21.0 Primary hyperparathyroidism
0.000 0.900 0.100
M45 Ankylosing spondylitis
0.099 0.901 0.000
E29.8 Other testicular dysfunction
0.000 0.901 0.098
E29.0 Testicular hyperfunction
0.000 0.901 0.098
E34.3 Short stature, not elsewhere classified
0.000 0.902 0.098
S02.4 Fracture of malar and maxillary bones
0.000 0.902 0.098
E34.5 Androgen resistance syndrome
0.000 0.903 0.096
E34.4 Constitutional tall stature
0.000 0.903 0.096
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.903 0.096
E34.1 Other hypersecretion of intestinal hormones
0.000 0.903 0.096
C15.4 Middle third of oesophagus
0.000 0.904 0.095
E22 Hyperfunction of pituitary gland
0.000 0.905 0.095
E34.9 Endocrine disorder, unspecified
0.000 0.907 0.093
C15.9 Oesophagus, unspecified
0.000 0.909 0.091
S02 Fracture of skull and facial bones
0.000 0.910 0.090
C25.1 Body of pancreas
0.000 0.914 0.086
C17 Malignant neoplasm of small intestine
0.000 0.915 0.085
E34.8 Other specified endocrine disorders
0.000 0.915 0.085
C25.3 Pancreatic duct
0.000 0.916 0.084
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.916 0.084
E11.3 With ophthalmic complications
0.000 0.917 0.083
E34.0 Carcinoid syndrome
0.000 0.917 0.083
C15.0 Cervical part of oesophagus
0.000 0.917 0.083
C25.2 Tail of pancreas
0.000 0.917 0.082
I83.0 Varicose veins of lower extremities with ulcer
0.081 0.919 0.000
S02.8 Fractures of other skull and facial bones
0.000 0.920 0.080
C17.0 Duodenum
0.000 0.920 0.080
S02.0 Fracture of vault of skull
0.000 0.920 0.080
E26.8 Other hyperaldosteronism
0.000 0.920 0.079
E26.1 Secondary hyperaldosteronism
0.000 0.920 0.079
C15.8 Overlapping lesion of oesophagus
0.000 0.921 0.079
C15.2 Abdominal part of oesophagus
0.000 0.921 0.079
C25.4 Endocrine pancreas
0.000 0.921 0.078
C15.1 Thoracic part of oesophagus
0.000 0.923 0.077
M45.X2 Ankylosing spondylitis (Cervical region)
0.077 0.923 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.076 0.924 0.000
C25.8 Overlapping lesion of pancreas
0.000 0.924 0.076
M45.X6 Ankylosing spondylitis (Lumbar region)
0.076 0.924 0.000
C24.0 Extrahepatic bile duct
0.000 0.924 0.075
S02.3 Fracture of orbital floor
0.000 0.926 0.074
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.926 0.074
C25.9 Pancreas, unspecified
0.000 0.927 0.073
S02.00 Fracture of vault of skull (closed)
0.000 0.927 0.072
C15.3 Upper third of oesophagus
0.000 0.928 0.072
S02.6 Fracture of mandible
0.000 0.929 0.071
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.071 0.929 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.071 0.929 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.071 0.929 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.071 0.929 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.071 0.929 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.071 0.929 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.929 0.070
S02.7 Multiple fractures involving skull and facial bones
0.000 0.930 0.070
S02.5 Fracture of tooth
0.000 0.931 0.069
E22.8 Other hyperfunction of pituitary gland
0.000 0.931 0.068
E22.1 Hyperprolactinaemia
0.000 0.932 0.068
E11.5 With peripheral circulatory complications
0.000 0.933 0.067
C25.7 Other parts of pancreas
0.000 0.934 0.066
C21 Malignant neoplasm of anus and anal canal
0.000 0.934 0.066
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.934 0.066
E29.1 Testicular hypofunction
0.000 0.935 0.065
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.935 0.064
E23 Hypofunction and other disorders of pituitary gland
0.000 0.938 0.062
S02.30 Fracture of orbital floor (closed)
0.000 0.938 0.062
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.938 0.062
C17.8 Overlapping lesion of small intestine
0.000 0.939 0.061
C17.3 Meckel's diverticulum
0.000 0.939 0.061
S02.2 Fracture of nasal bones
0.000 0.939 0.061
C24.8 Overlapping lesion of biliary tract
0.000 0.939 0.060
E14.9 Without complications
0.000 0.940 0.060
C24.9 Biliary tract, unspecified
0.000 0.941 0.058
S02.60 Fracture of mandible (closed)
0.000 0.942 0.058
C17.1 Jejunum
0.000 0.942 0.058
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.058 0.942 0.000
S02.81 Fractures of other skull and facial bones (open)
0.000 0.942 0.058
S02.01 Fracture of vault of skull (open)
0.000 0.943 0.057
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.944 0.056
S02.50 Fracture of tooth (closed)
0.000 0.945 0.055
C23 Malignant neoplasm of gallbladder
0.000 0.947 0.053
S02.31 Fracture of orbital floor (open)
0.000 0.947 0.053
Z71.8 Other specified counselling
0.053 0.947 0.000
S02.1 Fracture of base of skull
0.000 0.948 0.052
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.948 0.052
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.948 0.052
S02.61 Fracture of mandible (open)
0.000 0.948 0.051
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.950 0.050
S02.51 Fracture of tooth (open)
0.000 0.950 0.050
S02.21 Fracture of nasal bones (open)
0.000 0.951 0.049
E23.7 Disorder of pituitary gland, unspecified
0.000 0.951 0.049
E22.0 Acromegaly and pituitary gigantism
0.000 0.952 0.048
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.952 0.048
C21.2 Cloacogenic zone
0.000 0.952 0.047
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.954 0.046
E04 Other non-toxic goitre
0.003 0.954 0.042
C17.9 Small intestine, unspecified
0.000 0.955 0.045
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.955 0.045
E23.1 Drug-induced hypopituitarism
0.000 0.955 0.045
E27 Other disorders of adrenal gland
0.000 0.955 0.045
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.955 0.044
E83.4 Disorders of magnesium metabolism
0.040 0.956 0.004
E26.0 Primary hyperaldosteronism
0.001 0.957 0.042
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.958 0.041
C17.2 Ileum
0.000 0.960 0.040
E70-E90 Metabolic disorders
0.002 0.960 0.038
C21.0 Anus, unspecified
0.000 0.961 0.039
C26.8 Overlapping lesion of digestive system
0.000 0.962 0.037
C26.1 Spleen
0.000 0.962 0.037
C25.0 Head of pancreas
0.000 0.963 0.037
E11.4 With neurological complications
0.000 0.963 0.037
S02.11 Fracture of base of skull (open)
0.000 0.964 0.036
C21.1 Anal canal
0.000 0.964 0.036
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.964 0.036
E53.8 Deficiency of other specified B group vitamins
0.000 0.965 0.035
E78.2 Mixed hyperlipidaemia
0.000 0.966 0.034
C24.1 Ampulla of Vater
0.001 0.967 0.033
E27.1 Primary adrenocortical insufficiency
0.000 0.967 0.033
C22.7 Other specified carcinomas of liver
0.000 0.967 0.033
C22.4 Other sarcomas of liver
0.000 0.967 0.033
C22.3 Angiosarcoma of liver
0.000 0.967 0.033
C22.2 Hepatoblastoma
0.000 0.967 0.033
E78.5 Hyperlipidaemia, unspecified
0.000 0.967 0.033
E04.8 Other specified non-toxic goitre
0.002 0.967 0.031
C22.9 Liver, unspecified
0.000 0.967 0.033
I83.1 Varicose veins of lower extremities with inflammation
0.033 0.967 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.968 0.032
E27.0 Other adrenocortical overactivity
0.000 0.968 0.032
S02.20 Fracture of nasal bones (closed)
0.000 0.968 0.032
E11.9 Without complications
0.000 0.968 0.032
C18 Malignant neoplasm of colon
0.000 0.969 0.031
E73 Lactose intolerance
0.001 0.969 0.030
C18.9 Colon, unspecified
0.000 0.969 0.031
E78.1 Pure hyperglyceridaemia
0.000 0.970 0.030
E23.6 Other disorders of pituitary gland
0.001 0.970 0.029
C18.1 Appendix
0.000 0.971 0.029
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.971 0.028
K90-K93 Other diseases of the digestive system
0.000 0.971 0.029
E66 Obesity
0.000 0.971 0.029
E74 Other disorders of carbohydrate metabolism
0.001 0.971 0.028
E77 Disorders of glycoprotein metabolism
0.001 0.971 0.027
E76 Disorders of glycosaminoglycan metabolism
0.001 0.971 0.027
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.971 0.027
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.971 0.027
E27.9 Disorder of adrenal gland, unspecified
0.000 0.971 0.028
E78.6 Lipoprotein deficiency
0.000 0.972 0.028
E88 Other metabolic disorders
0.001 0.972 0.027
E85 Amyloidosis
0.001 0.972 0.027
C22.1 Intrahepatic bile duct carcinoma
0.000 0.972 0.028
C26.9 Ill-defined sites within the digestive system
0.000 0.972 0.027
E70 Disorders of aromatic amino-acid metabolism
0.001 0.973 0.026
E27.2 Addisonian crisis
0.000 0.973 0.027
E78.3 Hyperchylomicronaemia
0.000 0.973 0.027
E23.2 Diabetes insipidus
0.000 0.973 0.027
S02.10 Fracture of base of skull (closed)
0.000 0.973 0.027
E72 Other disorders of amino-acid metabolism
0.001 0.974 0.025
E79 Disorders of purine and pyrimidine metabolism
0.001 0.974 0.025
C26.0 Intestinal tract, part unspecified
0.000 0.974 0.026
E84 Cystic fibrosis
0.002 0.974 0.024
E73.9 Lactose intolerance, unspecified
0.000 0.975 0.024
C18.8 Overlapping lesion of colon
0.000 0.976 0.024
E78.4 Other hyperlipidaemia
0.000 0.977 0.023
E88.9 Metabolic disorder, unspecified
0.000 0.977 0.023
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.977 0.023
E04.0 Non-toxic diffuse goitre
0.003 0.977 0.020
S00-S09 Injuries to the head
0.000 0.977 0.023
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.977 0.022
E73.8 Other lactose intolerance
0.001 0.978 0.021
E73.1 Secondary lactase deficiency
0.001 0.978 0.021
E73.0 Congenital lactase deficiency
0.001 0.978 0.021
E85.4 Organ-limited amyloidosis
0.001 0.978 0.022
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.022 0.978 0.000
E75.5 Other lipid storage disorders
0.001 0.978 0.021
C16 Malignant neoplasm of stomach
0.000 0.978 0.022
S05 Injury of eye and orbit
0.000 0.978 0.022
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.979 0.021
E27.8 Other specified disorders of adrenal gland
0.000 0.979 0.021
E75.6 Lipid storage disorder, unspecified
0.001 0.979 0.020
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.979 0.020
E75.3 Sphingolipidosis, unspecified
0.001 0.979 0.020
E75.1 Other gangliosidosis
0.001 0.979 0.020
E75.0 GM2 gangliosidosis
0.001 0.979 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.979 0.021
E88.2 Lipomatosis, not elsewhere classified
0.001 0.979 0.021
E66.1 Drug-induced obesity
0.000 0.979 0.021
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.979 0.020
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.979 0.020
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.979 0.020
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.979 0.020
E74.2 Disorders of galactose metabolism
0.001 0.979 0.020
E74.1 Disorders of fructose metabolism
0.001 0.979 0.020
E71.3 Disorders of fatty-acid metabolism
0.001 0.979 0.020
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.979 0.020
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.979 0.020
E71.0 Maple-syrup-urine disease
0.001 0.979 0.020
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.979 0.020
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.979 0.020
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.979 0.020
E76.2 Other mucopolysaccharidoses
0.001 0.979 0.020
E76.1 Mucopolysaccharidosis, type II
0.001 0.979 0.020
E76.0 Mucopolysaccharidosis, type I
0.001 0.979 0.020
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.979 0.020
E77.8 Other disorders of glycoprotein metabolism
0.001 0.979 0.020
E77.1 Defects in glycoprotein degradation
0.001 0.979 0.020
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.979 0.020
C18.4 Transverse colon
0.000 0.979 0.021
E75.2 Other sphingolipidosis
0.001 0.979 0.020
E85.3 Secondary systemic amyloidosis
0.001 0.979 0.020
E74.0 Glycogen storage disease
0.001 0.980 0.020
E85.8 Other amyloidosis
0.001 0.980 0.019
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.980 0.019
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.980 0.019
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.980 0.019
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.980 0.019
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.980 0.019
E70.2 Disorders of tyrosine metabolism
0.001 0.980 0.019
E70.1 Other hyperphenylalaninaemias
0.001 0.980 0.019
E70.0 Classical phenylketonuria
0.001 0.980 0.019
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.980 0.019
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.981 0.018
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.981 0.018
E72.5 Disorders of glycine metabolism
0.001 0.981 0.018
E72.4 Disorders of ornithine metabolism
0.001 0.981 0.018
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.981 0.018
E72.2 Disorders of urea cycle metabolism
0.001 0.981 0.018
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.981 0.019
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.981 0.018
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.981 0.018
E79.1 Lesch-Nyhan syndrome
0.001 0.981 0.018
E72.0 Disorders of amino-acid transport
0.001 0.981 0.018
E23.0 Hypopituitarism
0.000 0.981 0.019
E70.3 Albinism
0.001 0.981 0.018
E84.8 Cystic fibrosis with other manifestations
0.001 0.981 0.017
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.981 0.017
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.981 0.019
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.982 0.017
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.982 0.018
S05.8 Other injuries of eye and orbit
0.000 0.982 0.018
E88.8 Other specified metabolic disorders
0.001 0.982 0.017
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.982 0.018
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.982 0.017

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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