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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3131091
log Bayes Factor = 52.8577
Chromosome 6   position 29,073,094  (GRCh37) Explore rs3131091 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E16.2 Hypoglycaemia, unspecified
0.000 0.003 0.997
E16 Other disorders of pancreatic internal secretion
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.003 0.997
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.003 0.997
E00-E07 Disorders of thyroid gland
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.012 0.988
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.042 0.958
E10.2 With renal complications
0.000 0.044 0.956
E10.4 With neurological complications
0.000 0.115 0.885
E10.1 With ketoacidosis
0.000 0.135 0.865
E05.8 Other thyrotoxicosis
0.000 0.196 0.804
E16.1 Other hypoglycaemia
0.000 0.205 0.795
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.215 0.785
E13 Other specified diabetes mellitus
0.000 0.226 0.774
E40-E46 Malnutrition
0.000 0.238 0.762
E10.7 With multiple complications
0.000 0.245 0.755
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.286 0.714
E00 Congenital iodine-deficiency syndrome
0.000 0.286 0.714
E10.0 With coma
0.000 0.287 0.713
E14 Unspecified diabetes mellitus
0.000 0.320 0.680
E10.5 With peripheral circulatory complications
0.000 0.328 0.672
E10.6 With other specified complications
0.000 0.342 0.658
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.358 0.642
E07 Other disorders of thyroid
0.000 0.363 0.637
E13.9 Without complications
0.000 0.377 0.623
E06 Thyroiditis
0.000 0.385 0.615
E46 Unspecified protein-energy malnutrition
0.000 0.406 0.594
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.412 0.587
E14.3 With ophthalmic complications
0.000 0.420 0.580
E13.8 With unspecified complications
0.000 0.445 0.555
E13.7 With multiple complications
0.000 0.445 0.555
E13.6 With other specified complications
0.000 0.445 0.555
E13.5 With peripheral circulatory complications
0.000 0.445 0.555
E13.4 With neurological complications
0.000 0.445 0.555
E13.2 With renal complications
0.000 0.445 0.555
E13.1 With ketoacidosis
0.000 0.445 0.555
E13.0 With coma
0.000 0.445 0.555
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.453 0.547
E45 Retarded development following protein-energy malnutrition
0.000 0.453 0.547
E43 Unspecified severe protein-energy malnutrition
0.000 0.453 0.547
E42 Marasmic kwashiorkor
0.000 0.453 0.547
E41 Nutritional marasmus
0.000 0.453 0.547
E40 Kwashiorkor
0.000 0.453 0.547
E03 Other hypothyroidism
0.000 0.458 0.542
E13.3 With ophthalmic complications
0.000 0.458 0.542
E14.1 With ketoacidosis
0.000 0.461 0.539
E10.8 With unspecified complications
0.000 0.470 0.530
K90 Intestinal malabsorption
0.000 0.473 0.527
E14.8 With unspecified complications
0.000 0.480 0.520
E14.4 With neurological complications
0.000 0.485 0.515
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E06.9 Thyroiditis, unspecified
0.000 0.488 0.512
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.488 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.488 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.488 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.488 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.488 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.488 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.488 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.488 0.512
E07.8 Other specified disorders of thyroid
0.000 0.494 0.506
E14.6 With other specified complications
0.000 0.495 0.505
E14.7 With multiple complications
0.000 0.512 0.488
E14.5 With peripheral circulatory complications
0.000 0.532 0.467
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.535 0.465
E14.0 With coma
0.000 0.541 0.459
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.542 0.457
E07.1 Dyshormogenetic goitre
0.000 0.543 0.457
E07.0 Hypersecretion of calcitonin
0.000 0.543 0.457
E14.2 Withrenal complications
0.000 0.548 0.451
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.449 0.551 0.000
E06.1 Subacute thyroiditis
0.000 0.552 0.448
E06.4 Drug-induced thyroiditis
0.000 0.559 0.441
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.559 0.441
E06.0 Acute thyroiditis
0.000 0.559 0.441
E06.5 Other chronic thyroiditis
0.000 0.572 0.428
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.591 0.409
E44.1 Mild protein-energy malnutrition
0.000 0.608 0.392
E44.0 Moderate protein-energy malnutrition
0.000 0.608 0.392
E03.5 Myxoedema coma
0.000 0.611 0.388
E03.4 Atrophy of thyroid (acquired)
0.000 0.611 0.388
E03.3 Postinfectious hypothyroidism
0.000 0.611 0.388
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.614 0.385
E03.1 Congenital hypothyroidism without goitre
0.000 0.622 0.378
K90.3 Pancreatic steatorrhoea
0.000 0.622 0.378
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.622 0.378
K90.1 Tropical sprue
0.000 0.622 0.378
K90.8 Other intestinal malabsorption
0.000 0.631 0.369
E65-E68 Obesity and other hyperalimentation
0.000 0.654 0.345
E03.8 Other specified hypothyroidism
0.000 0.662 0.338
E50-E64 Other nutritional deficiencies
0.000 0.685 0.315
K90.9 Intestinal malabsorption, unspecified
0.000 0.705 0.295
E07.9 Disorder of thyroid, unspecified
0.000 0.716 0.284
E03.9 Hypothyroidism, unspecified
0.000 0.717 0.283
E67 Other hyperalimentation
0.000 0.752 0.248
E68 Sequelae of hyperalimentation
0.000 0.752 0.248
E20-E35 Disorders of other endocrine glands
0.000 0.774 0.226
E51 Thiamine deficiency
0.000 0.774 0.226
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.774 0.226
E50 Vitamin A deficiency
0.000 0.774 0.226
E60 Dietary zinc deficiency
0.000 0.774 0.226
E59 Dietary selenium deficiency
0.000 0.774 0.226
E52 Niacin deficiency [pellagra]
0.000 0.774 0.226
E54 Ascorbic acid deficiency
0.000 0.778 0.222
E56 Other vitamin deficiencies
0.000 0.785 0.215
E24 Cushing's syndrome
0.000 0.790 0.210
E58 Dietary calcium deficiency
0.000 0.792 0.208
R31 Unspecified haematuria
0.205 0.795 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.795 0.205
E63 Other nutritional deficiencies
0.000 0.795 0.205
E65 Localised adiposity
0.000 0.797 0.202
E21.3 Hyperparathyroidism, unspecified
0.000 0.803 0.197
E55 Vitamin D deficiency
0.000 0.806 0.194
E61 Deficiency of other nutrient elements
0.000 0.809 0.191
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.810 0.190
E24.9 Cushing's syndrome, unspecified
0.000 0.818 0.182
E67.8 Other specified hyperalimentation
0.000 0.822 0.178
E67.3 Hypervitaminosis D
0.000 0.822 0.178
E67.2 Megavitamin-B6 syndrome
0.000 0.822 0.178
E67.1 Hypercarotenaemia
0.000 0.822 0.178
E67.0 Hypervitaminosis A
0.000 0.822 0.178
E24.0 Pituitary-dependent Cushing's disease
0.000 0.824 0.176
E06.3 Autoimmune thyroiditis
0.000 0.832 0.168
E24.2 Drug-induced Cushing's syndrome
0.000 0.834 0.166
E53 Deficiency of other B group vitamins
0.000 0.835 0.165
E20 Hypoparathyroidism
0.000 0.835 0.165
E51.2 Wernicke's encephalopathy
0.000 0.837 0.163
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.837 0.162
E32 Diseases of thymus
0.000 0.837 0.162
E30 Disorders of puberty, not elsewhere classified
0.000 0.837 0.162
E51.9 Thiamine deficiency, unspecified
0.000 0.838 0.162
E51.8 Other manifestations of thiamine deficiency
0.000 0.838 0.162
E51.1 Beriberi
0.000 0.838 0.162
E50.9 Vitamin A deficiency, unspecified
0.000 0.838 0.162
E50.8 Other manifestations of vitamin A deficiency
0.000 0.838 0.162
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.838 0.162
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.838 0.162
E50.5 Vitamin A deficiency with night blindness
0.000 0.838 0.162
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.838 0.162
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.838 0.162
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.838 0.162
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.838 0.162
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.838 0.162
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.838 0.162
E64.8 Sequelae of other nutritional deficiencies
0.000 0.838 0.162
E64.3 Sequelae of rickets
0.000 0.838 0.162
E64.2 Sequelae of vitamin C deficiency
0.000 0.838 0.162
E64.1 Sequelae of vitamin A deficiency
0.000 0.838 0.162
E64.0 Sequelae of protein-energy malnutrition
0.000 0.838 0.162
E21.4 Other specified disorders of parathyroid gland
0.000 0.839 0.161
E25 Adrenogenital disorders
0.000 0.842 0.158
M45.X9 Ankylosing spondylitis (Site unspecified)
0.158 0.842 0.000
E31 Polyglandular dysfunction
0.000 0.844 0.156
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.845 0.155
E56.9 Vitamin deficiency, unspecified
0.000 0.846 0.154
E56.8 Deficiency of other vitamins
0.000 0.846 0.154
E56.0 Deficiency of vitamin E
0.000 0.846 0.154
E24.8 Other Cushing's syndrome
0.000 0.849 0.151
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.849 0.151
E24.3 Ectopic ACTH syndrome
0.000 0.849 0.151
E24.1 Nelson's syndrome
0.000 0.849 0.151
E21.2 Other hyperparathyroidism
0.000 0.851 0.149
E63.8 Other specified nutritional deficiencies
0.000 0.853 0.147
E63.1 Imbalance of constituents of food intake
0.000 0.853 0.147
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.853 0.147
E56.1 Deficiency of vitamin K
0.000 0.857 0.143
E28 Ovarian dysfunction
0.000 0.859 0.141
E55.0 Rickets, active
0.000 0.861 0.139
E61.9 Deficiency of nutrient element, unspecified
0.000 0.863 0.137
E61.8 Deficiency of other specified nutrient elements
0.000 0.863 0.137
E61.7 Deficiency of multiple nutrient elements
0.000 0.863 0.137
E61.6 Vanadium deficiency
0.000 0.863 0.137
E61.5 Molybdenum deficiency
0.000 0.863 0.137
E61.4 Chromium deficiency
0.000 0.863 0.137
E61.3 Manganese deficiency
0.000 0.863 0.137
E61.0 Copper deficiency
0.000 0.863 0.137
E11 Non-insulin-dependent diabetes mellitus
0.000 0.863 0.137
E83 Disorders of mineral metabolism
0.131 0.865 0.003
E29 Testicular dysfunction
0.000 0.866 0.134
C15-C26 Malignant neoplasms of digestive organs
0.000 0.870 0.130
C20 Malignant neoplasm of rectum
0.000 0.870 0.130
E53.9 Vitamin B deficiency, unspecified
0.000 0.871 0.129
E34 Other endocrine disorders
0.000 0.874 0.126
E63.9 Nutritional deficiency, unspecified
0.000 0.874 0.126
E61.1 Iron deficiency
0.000 0.874 0.126
C15 Malignant neoplasm of oesophagus
0.000 0.875 0.125
E11.6 With other specified complications
0.000 0.876 0.124
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.878 0.122
E20.9 Hypoparathyroidism, unspecified
0.000 0.879 0.120
E53.1 Pyridoxine deficiency
0.000 0.881 0.119
E53.0 Riboflavin deficiency
0.000 0.881 0.119
E20.8 Other hypoparathyroidism
0.000 0.882 0.118
E20.1 Pseudohypoparathyroidism
0.000 0.882 0.118
E20.0 Idiopathic hypoparathyroidism
0.000 0.882 0.118
E61.2 Magnesium deficiency
0.000 0.882 0.118
E30.9 Disorder of puberty, unspecified
0.000 0.883 0.117
E30.8 Other disorders of puberty
0.000 0.883 0.117
E30.1 Precocious puberty
0.000 0.883 0.117
E30.0 Delayed puberty
0.000 0.883 0.117
E32.9 Disease of thymus, unspecified
0.000 0.883 0.117
E32.8 Other diseases of thymus
0.000 0.883 0.117
E32.1 Abscess of thymus
0.000 0.883 0.117
E32.0 Persistent hyperplasia of thymus
0.000 0.883 0.117
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.883 0.117
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.883 0.117
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.883 0.117
C15.5 Lower third of oesophagus
0.000 0.885 0.115
C25 Malignant neoplasm of pancreas
0.000 0.886 0.114
E25.9 Adrenogenital disorder, unspecified
0.000 0.886 0.114
E25.8 Other adrenogenital disorders
0.000 0.886 0.114
E31.9 Polyglandular dysfunction, unspecified
0.000 0.888 0.112
E31.8 Other polyglandular dysfunction
0.000 0.888 0.112
E31.1 Polyglandular hyperfunction
0.000 0.888 0.112
E83.3 Disorders of phosphorus metabolism
0.109 0.890 0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.890 0.109
E55.9 Vitamin D deficiency, unspecified
0.000 0.893 0.107
C15.4 Middle third of oesophagus
0.000 0.893 0.107
E31.0 Autoimmune polyglandular failure
0.000 0.895 0.105
E11.0 With coma
0.000 0.895 0.105
E26 Hyperaldosteronism
0.001 0.896 0.103
C15.9 Oesophagus, unspecified
0.000 0.897 0.103
E11.1 With ketoacidosis
0.000 0.897 0.102
E28.9 Ovarian dysfunction, unspecified
0.000 0.899 0.101
E28.8 Other ovarian dysfunction
0.000 0.899 0.101
E28.1 Androgen excess
0.000 0.899 0.101
E28.0 Oestrogen excess
0.000 0.899 0.101
E21.0 Primary hyperparathyroidism
0.000 0.900 0.100
E11.2 With renal complications
0.000 0.901 0.099
E11.7 With multiple complications
0.000 0.902 0.098
C25.1 Body of pancreas
0.000 0.902 0.097
E22 Hyperfunction of pituitary gland
0.000 0.903 0.097
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.903 0.097
E83.8 Other disorders of mineral metabolism
0.094 0.903 0.003
E83.2 Disorders of zinc metabolism
0.094 0.903 0.003
E83.0 Disorders of copper metabolism
0.094 0.903 0.003
C17 Malignant neoplasm of small intestine
0.000 0.903 0.096
E28.2 Polycystic ovarian syndrome
0.000 0.904 0.096
E29.9 Testicular dysfunction, unspecified
0.000 0.904 0.096
E29.8 Other testicular dysfunction
0.000 0.904 0.096
E29.0 Testicular hyperfunction
0.000 0.904 0.096
C25.3 Pancreatic duct
0.000 0.904 0.096
E83.9 Disorder of mineral metabolism, unspecified
0.093 0.904 0.003
C15.0 Cervical part of oesophagus
0.000 0.906 0.094
C25.2 Tail of pancreas
0.000 0.906 0.094
E34.3 Short stature, not elsewhere classified
0.000 0.907 0.092
E34.5 Androgen resistance syndrome
0.000 0.909 0.091
E34.4 Constitutional tall stature
0.000 0.909 0.091
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.909 0.091
E34.1 Other hypersecretion of intestinal hormones
0.000 0.909 0.091
C17.0 Duodenum
0.000 0.909 0.091
C15.8 Overlapping lesion of oesophagus
0.000 0.910 0.090
C15.2 Abdominal part of oesophagus
0.000 0.910 0.090
C25.4 Endocrine pancreas
0.000 0.911 0.089
C15.1 Thoracic part of oesophagus
0.000 0.912 0.088
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.912 0.088
C24.0 Extrahepatic bile duct
0.000 0.913 0.087
E28.3 Primary ovarian failure
0.000 0.913 0.087
C25.8 Overlapping lesion of pancreas
0.000 0.913 0.087
E34.9 Endocrine disorder, unspecified
0.000 0.916 0.084
I83 Varicose veins of lower extremities
0.084 0.916 0.000
C15.3 Upper third of oesophagus
0.000 0.918 0.082
E11.8 With unspecified complications
0.000 0.919 0.081
C25.9 Pancreas, unspecified
0.000 0.919 0.081
E34.8 Other specified endocrine disorders
0.000 0.920 0.080
E34.0 Carcinoid syndrome
0.000 0.922 0.078
C21 Malignant neoplasm of anus and anal canal
0.000 0.924 0.076
S02.4 Fracture of malar and maxillary bones
0.000 0.924 0.076
C25.7 Other parts of pancreas
0.000 0.924 0.076
M45 Ankylosing spondylitis
0.075 0.925 0.000
E26.8 Other hyperaldosteronism
0.000 0.925 0.074
E26.1 Secondary hyperaldosteronism
0.000 0.925 0.074
E14.9 Without complications
0.000 0.927 0.073
Z71.8 Other specified counselling
0.071 0.929 0.000
E22.8 Other hyperfunction of pituitary gland
0.000 0.930 0.070
C24.8 Overlapping lesion of biliary tract
0.000 0.930 0.070
C17.8 Overlapping lesion of small intestine
0.000 0.931 0.069
C17.3 Meckel's diverticulum
0.000 0.931 0.069
E22.1 Hyperprolactinaemia
0.000 0.931 0.069
S02 Fracture of skull and facial bones
0.000 0.931 0.069
C24.9 Biliary tract, unspecified
0.000 0.932 0.067
E29.1 Testicular hypofunction
0.000 0.933 0.067
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.934 0.066
C17.1 Jejunum
0.000 0.934 0.066
E26.9 Hyperaldosteronism, unspecified
0.001 0.937 0.063
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.938 0.062
C23 Malignant neoplasm of gallbladder
0.000 0.939 0.061
E23 Hypofunction and other disorders of pituitary gland
0.000 0.939 0.061
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.940 0.060
M45.X2 Ankylosing spondylitis (Cervical region)
0.060 0.940 0.000
S02.0 Fracture of vault of skull
0.000 0.940 0.060
S02.8 Fractures of other skull and facial bones
0.000 0.941 0.059
I83.0 Varicose veins of lower extremities with ulcer
0.058 0.942 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.057 0.942 0.000
S02.3 Fracture of orbital floor
0.000 0.944 0.056
C21.2 Cloacogenic zone
0.000 0.945 0.055
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.054 0.945 0.000
S02.6 Fracture of mandible
0.000 0.945 0.054
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.054 0.946 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.054 0.946 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.054 0.946 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.054 0.946 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.054 0.946 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.054 0.946 0.000
S02.00 Fracture of vault of skull (closed)
0.000 0.946 0.054
S02.7 Multiple fractures involving skull and facial bones
0.000 0.946 0.054
S02.5 Fracture of tooth
0.000 0.947 0.053
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.947 0.053
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.947 0.053
E22.0 Acromegaly and pituitary gigantism
0.000 0.948 0.052
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.949 0.051
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.951 0.049
C17.9 Small intestine, unspecified
0.000 0.951 0.049
E11.3 With ophthalmic complications
0.000 0.951 0.049
E23.7 Disorder of pituitary gland, unspecified
0.000 0.952 0.048
E11.5 With peripheral circulatory complications
0.000 0.952 0.048
S02.30 Fracture of orbital floor (closed)
0.000 0.952 0.048
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.953 0.047
S02.2 Fracture of nasal bones
0.000 0.953 0.047
E04 Other non-toxic goitre
0.003 0.953 0.043
C17.2 Ileum
0.000 0.954 0.045
C21.0 Anus, unspecified
0.000 0.955 0.045
C26.8 Overlapping lesion of digestive system
0.000 0.955 0.044
C26.1 Spleen
0.000 0.955 0.044
S02.60 Fracture of mandible (closed)
0.000 0.956 0.044
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.956 0.044
E23.1 Drug-induced hypopituitarism
0.000 0.956 0.044
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.044 0.956 0.000
S02.01 Fracture of vault of skull (open)
0.000 0.957 0.043
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.957 0.043
E83.4 Disorders of magnesium metabolism
0.041 0.957 0.002
S02.81 Fractures of other skull and facial bones (open)
0.000 0.957 0.043
S02.50 Fracture of tooth (closed)
0.000 0.958 0.042
C18 Malignant neoplasm of colon
0.000 0.958 0.042
E27 Other disorders of adrenal gland
0.000 0.958 0.042
C21.1 Anal canal
0.000 0.958 0.041
C18.9 Colon, unspecified
0.000 0.959 0.041
S02.31 Fracture of orbital floor (open)
0.000 0.959 0.041
C25.0 Head of pancreas
0.000 0.959 0.040
E26.0 Primary hyperaldosteronism
0.001 0.959 0.040
S02.1 Fracture of base of skull
0.000 0.960 0.040
C18.1 Appendix
0.000 0.960 0.040
S02.61 Fracture of mandible (open)
0.000 0.961 0.039
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.961 0.039
S02.51 Fracture of tooth (open)
0.000 0.962 0.038
C24.1 Ampulla of Vater
0.001 0.962 0.038
C22.7 Other specified carcinomas of liver
0.000 0.962 0.038
C22.4 Other sarcomas of liver
0.000 0.962 0.038
C22.3 Angiosarcoma of liver
0.000 0.962 0.038
C22.2 Hepatoblastoma
0.000 0.962 0.038
C22.9 Liver, unspecified
0.000 0.962 0.038
S02.21 Fracture of nasal bones (open)
0.000 0.962 0.038
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.966 0.034
E04.8 Other specified non-toxic goitre
0.003 0.966 0.031
K90-K93 Other diseases of the digestive system
0.000 0.967 0.033
C26.9 Ill-defined sites within the digestive system
0.000 0.967 0.032
C26.0 Intestinal tract, part unspecified
0.000 0.967 0.032
C22.1 Intrahepatic bile duct carcinoma
0.000 0.968 0.032
C18.8 Overlapping lesion of colon
0.000 0.968 0.032
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.968 0.032
E27.1 Primary adrenocortical insufficiency
0.000 0.969 0.031
E27.5 Adrenomedullary hyperfunction
0.000 0.970 0.030
E27.0 Other adrenocortical overactivity
0.000 0.970 0.030
E53.8 Deficiency of other specified B group vitamins
0.000 0.971 0.029
E23.6 Other disorders of pituitary gland
0.001 0.971 0.029
E11.4 With neurological complications
0.000 0.972 0.028
C18.4 Transverse colon
0.000 0.972 0.028
S02.11 Fracture of base of skull (open)
0.000 0.972 0.028
E23.2 Diabetes insipidus
0.000 0.973 0.026
S00-S09 Injuries to the head
0.000 0.973 0.027
E66 Obesity
0.000 0.974 0.026
C16 Malignant neoplasm of stomach
0.000 0.974 0.026
E27.2 Addisonian crisis
0.000 0.974 0.025
S05 Injury of eye and orbit
0.000 0.974 0.026
E27.9 Disorder of adrenal gland, unspecified
0.000 0.974 0.025
S02.20 Fracture of nasal bones (closed)
0.000 0.975 0.025
E04.0 Non-toxic diffuse goitre
0.003 0.975 0.022
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.976 0.024
C18.6 Descending colon
0.000 0.977 0.023
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.977 0.023
S00 Superficial injury of head
0.000 0.978 0.022
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.978 0.022
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.022 0.978 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.022 0.978 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.978 0.022
S05.8 Other injuries of eye and orbit
0.000 0.979 0.021
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.979 0.021
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.979 0.021
S02.10 Fracture of base of skull (closed)
0.000 0.979 0.021
S00.0 Superficial injury of scalp
0.000 0.979 0.021
C18.7 Sigmoid colon
0.000 0.980 0.020
E27.8 Other specified disorders of adrenal gland
0.000 0.980 0.020
H40.2 Primary angle-closure glaucoma
0.020 0.980 0.000
C18.3 Hepatic flexure
0.000 0.980 0.020
S07 Crushing injury of head
0.000 0.981 0.019
S04 Injury of cranial nerves
0.000 0.981 0.019
S08 Traumatic amputation of part of head
0.000 0.981 0.019
E70-E90 Metabolic disorders
0.002 0.981 0.017
E66.1 Drug-induced obesity
0.000 0.981 0.019
S05.1 Contusion of eyeball and orbital tissues
0.000 0.981 0.019
S00.4 Superficial injury of ear
0.000 0.981 0.019
S00.1 Contusion of eyelid and periocular area
0.000 0.981 0.019
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.981 0.019
E23.0 Hypopituitarism
0.000 0.981 0.018
S05.7 Avulsion of eye
0.000 0.981 0.018
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.981 0.018
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.982 0.018
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.982 0.018
C16.5 Lesser curvature of stomach, unspecified
0.000 0.982 0.018
C16.2 Body of stomach
0.000 0.982 0.017
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.983 0.017
K93.1 Megacolon in Chagas' disease
0.000 0.983 0.017
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.983 0.017
C16.6 Greater curvature of stomach, unspecified
0.000 0.983 0.017
S09 Other and unspecified injuries of head
0.000 0.983 0.017
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.983 0.017
C16.8 Overlapping lesion of stomach
0.000 0.983 0.017
C16.4 Pylorus
0.000 0.983 0.016
C16.9 Stomach, unspecified
0.000 0.984 0.016
E11.9 Without complications
0.000 0.984 0.016
S05.9 Injury of eye and orbit, part unspecified
0.000 0.984 0.016
S00.7 Multiple superficial injuries of head
0.000 0.984 0.016
C16.1 Fundus of stomach
0.000 0.984 0.015
C16.0 Cardia
0.000 0.984 0.016
S09.8 Other specified injuries of head
0.000 0.984 0.016
E66.0 Obesity due to excess calories
0.000 0.985 0.015
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.985 0.015
C16.3 Pyloric antrum
0.000 0.985 0.015
E78.2 Mixed hyperlipidaemia
0.000 0.985 0.015
E73 Lactose intolerance
0.001 0.985 0.014
S04.9 Injury of unspecified cranial nerve
0.000 0.986 0.014
S04.8 Injury of other cranial nerves
0.000 0.986 0.014
S04.7 Injury of accessory nerve
0.000 0.986 0.014
S04.6 Injury of acoustic nerve
0.000 0.986 0.014
S04.5 Injury of facial nerve
0.000 0.986 0.014
S04.4 Injury of abducent nerve
0.000 0.986 0.014
S04.3 Injury of trigeminal nerve
0.000 0.986 0.014
S04.2 Injury of trochlear nerve
0.000 0.986 0.014
S04.1 Injury of oculomotor nerve
0.000 0.986 0.014
S04.0 Injury of optic nerve and pathways
0.000 0.986 0.014
S07.9 Crushing injury of head, part unspecified
0.000 0.986 0.014
S07.8 Crushing injury of other parts of head
0.000 0.986 0.014
S07.1 Crushing injury of skull
0.000 0.986 0.014
S07.0 Crushing injury of face
0.000 0.986 0.014
S00.5 Superficial injury of lip and oral cavity
0.000 0.986 0.014
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.986 0.013
S08.9 Traumatic amputation of unspecified part of head
0.000 0.986 0.014
S08.8 Traumatic amputation of other parts of head
0.000 0.986 0.014
S08.0 Avulsion of scalp
0.000 0.986 0.014
E77 Disorders of glycoprotein metabolism
0.001 0.986 0.012
E76 Disorders of glycosaminoglycan metabolism
0.001 0.986 0.012
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.986 0.012
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.986 0.012
E74 Other disorders of carbohydrate metabolism
0.001 0.986 0.013
S03.0 Dislocation of jaw
0.000 0.986 0.014
S03.2 Dislocation of tooth
0.000 0.986 0.014
S08.1 Traumatic amputation of ear
0.000 0.986 0.013
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.000 0.986 0.013
S03.4 Sprain and strain of jaw
0.000 0.986 0.013
S03.3 Dislocation of other and unspecified parts of head
0.000 0.986 0.013
C22.0 Liver cell carcinoma
0.001 0.987 0.013
E70 Disorders of aromatic amino-acid metabolism
0.002 0.987 0.012
E78.5 Hyperlipidaemia, unspecified
0.000 0.987 0.013
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.987 0.013
E85 Amyloidosis
0.001 0.987 0.012
E72 Other disorders of amino-acid metabolism
0.002 0.987 0.011
E78.1 Pure hyperglyceridaemia
0.000 0.987 0.013
E79 Disorders of purine and pyrimidine metabolism
0.002 0.987 0.011
S06 Intracranial injury
0.000 0.987 0.013
E84 Cystic fibrosis
0.002 0.987 0.011
E88 Other metabolic disorders
0.001 0.987 0.012
S09.7 Multiple injuries of head
0.000 0.988 0.012
S09.1 Injury of muscle and tendon of head
0.000 0.988 0.012
E78.6 Lipoprotein deficiency
0.000 0.988 0.012
C18.5 Splenic flexure
0.000 0.988 0.012
S03.1 Dislocation of septal cartilage of nose
0.000 0.988 0.012

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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