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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3131622
log Bayes Factor = 142.663
Chromosome 6   position 31,420,500  (GRCh37) Explore rs3131622 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M45 Ankylosing spondylitis
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
E14 Unspecified diabetes mellitus
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.993 0.007 0.000
E14.3 With ophthalmic complications
0.991 0.009 0.000
E83.1 Disorders of iron metabolism
0.000 0.012 0.988
E10.1 With ketoacidosis
0.984 0.016 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.982 0.018 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.979 0.021 0.000
M06.9 Rheumatoid arthritis, unspecified
0.976 0.024 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.976 0.024 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.973 0.027 0.000
C85.1 B-cell lymphoma, unspecified
0.965 0.035 0.000
E06 Thyroiditis
0.949 0.051 0.000
E10.2 With renal complications
0.939 0.061 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.927 0.073 0.000
E06.3 Autoimmune thyroiditis
0.916 0.084 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.912 0.088 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.907 0.093 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.904 0.096 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.896 0.104 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.883 0.117 0.000
C81 Hodgkin's disease
0.882 0.118 0.000
E10.4 With neurological complications
0.857 0.143 0.000
E07 Other disorders of thyroid
0.853 0.147 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.848 0.152 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.841 0.159 0.000
C81.9 Hodgkin's disease, unspecified
0.834 0.166 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.832 0.168 0.000
M06 Other rheumatoid arthritis
0.828 0.172 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.826 0.174 0.000
E14.8 With unspecified complications
0.825 0.174 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.822 0.177 0.000
E03.8 Other specified hypothyroidism
0.819 0.181 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.811 0.189 0.000
M35.0 Sicca syndrome [Sjogren]
0.809 0.191 0.000
C83.3 Large cell (diffuse)
0.806 0.194 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.805 0.195 0.000
E10.7 With multiple complications
0.785 0.215 0.000
M35 Other systemic involvement of connective tissue
0.781 0.219 0.000
E10.8 With unspecified complications
0.776 0.224 0.000
E14.5 With peripheral circulatory complications
0.775 0.225 0.000
M05-M14 Inflammatory polyarthropathies
0.775 0.225 0.000
E14.9 Without complications
0.749 0.251 0.000
E07.9 Disorder of thyroid, unspecified
0.743 0.257 0.000
E14.2 Withrenal complications
0.741 0.259 0.000
M45-M49 Spondylopathies
0.738 0.262 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.735 0.264 0.000
E14.4 With neurological complications
0.729 0.271 0.000
E06.5 Other chronic thyroiditis
0.728 0.272 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.724 0.276 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.723 0.277 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.720 0.280 0.000
C88 Malignant immunoproliferative diseases
0.718 0.282 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.718 0.282 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.717 0.283 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.717 0.283 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.717 0.283 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.717 0.283 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M07 Psoriatic and enteropathic arthropathies
0.716 0.284 0.000
M20-M25 Other joint disorders
0.716 0.284 0.000
E14.6 With other specified complications
0.715 0.285 0.000
E14.7 With multiple complications
0.715 0.285 0.000
E14.0 With coma
0.715 0.285 0.000
C81.1 Nodular sclerosis
0.712 0.288 0.000
C83.7 Burkitt's tumour
0.708 0.292 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.702 0.298 0.000
C84.5 Other and unspecified T-cell lymphomas
0.701 0.299 0.000
C85.0 Lymphosarcoma
0.700 0.300 0.000
M34 Systemic sclerosis
0.698 0.302 0.000
C82.2 Large cell, follicular
0.695 0.305 0.000
E14.1 With ketoacidosis
0.691 0.309 0.000
E06.9 Thyroiditis, unspecified
0.690 0.310 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.689 0.311 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.683 0.317 0.000
C81.2 Mixed cellularity
0.682 0.318 0.000
E06.4 Drug-induced thyroiditis
0.681 0.319 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.681 0.319 0.000
E06.0 Acute thyroiditis
0.681 0.319 0.000
M07.3 Other psoriatic arthropathies
0.680 0.320 0.000
C91 Lymphoid leukaemia
0.678 0.322 0.000
M35.7 Hypermobility syndrome
0.675 0.325 0.000
E10.5 With peripheral circulatory complications
0.672 0.327 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.672 0.328 0.000
M35.1 Other overlap syndromes
0.669 0.331 0.000
C86 Other specified types of T/NK-cell lymphoma
0.665 0.334 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.665 0.335 0.000
C94 Other leukaemias of specified cell type
0.665 0.335 0.000
C82.3 Follicular lymphoma grade IIIa
0.664 0.335 0.000
E10.6 With other specified complications
0.663 0.337 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.661 0.339 0.000
E13 Other specified diabetes mellitus
0.660 0.340 0.000
M08 Juvenile arthritis
0.643 0.357 0.000
M34.1 CR(E)ST syndrome
0.643 0.357 0.000
C82.0 Small cleaved cell, follicular
0.639 0.361 0.000
C81.0 Lymphocytic predominance
0.639 0.361 0.000
C84.0 Mycosis fungoides
0.637 0.363 0.000
M06.1 Adult-onset Still's disease
0.634 0.366 0.000
C82.6 Cutaneous follicle centre lymphoma
0.633 0.367 0.000
C82.5 Diffuse follicle centre lymphoma
0.633 0.367 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.633 0.367 0.000
C81.3 Lymphocytic depletion
0.633 0.367 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.630 0.370 0.000
E10.0 With coma
0.627 0.372 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.627 0.373 0.000
M11 Other crystal arthropathies
0.626 0.374 0.000
M34.9 Systemic sclerosis, unspecified
0.623 0.377 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.621 0.379 0.000
E07.8 Other specified disorders of thyroid
0.621 0.379 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.614 0.386 0.000
E07.1 Dyshormogenetic goitre
0.611 0.388 0.000
E07.0 Hypersecretion of calcitonin
0.611 0.388 0.000
C82.4 Follicular lymphoma grade IIIb
0.605 0.395 0.000
M35.3 Polymyalgia rheumatica
0.603 0.397 0.000
C91.9 Lymphoid leukaemia, unspecified
0.598 0.402 0.000
E50-E64 Other nutritional deficiencies
0.594 0.406 0.000
M06.2 Rheumatoid bursitis
0.594 0.406 0.000
C83.6 Undifferentiated (diffuse)
0.592 0.408 0.000
C83.5 Lymphoblastic (diffuse)
0.592 0.408 0.000
C83.4 Immunoblastic (diffuse)
0.592 0.408 0.000
C83.2 Mixed small and large cell (diffuse)
0.592 0.408 0.000
C83.1 Small cleaved cell (diffuse)
0.592 0.408 0.000
C93 Monocytic leukaemia
0.588 0.412 0.000
E06.1 Subacute thyroiditis
0.583 0.417 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.582 0.418 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.582 0.418 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.582 0.418 0.000
C84.3 Lymphoepithelioid lymphoma
0.582 0.418 0.000
C84.2 T-zone lymphoma
0.582 0.418 0.000
C84.1 Sezary's diease
0.582 0.418 0.000
M00-M03 Infectious arthropathies
0.579 0.421 0.000
M32 Systemic lupus erythematosus
0.577 0.423 0.000
C81.7 Other Hodgkin's disease
0.574 0.426 0.000
E40-E46 Malnutrition
0.570 0.430 0.000
M06.4 Inflammatory polyarthropathy
0.567 0.433 0.000
M34.8 Other forms of systemic sclerosis
0.566 0.434 0.000
M06.8 Other specified rheumatoid arthritis
0.565 0.435 0.000
E03.1 Congenital hypothyroidism without goitre
0.563 0.437 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.562 0.438 0.000
C91.5 Adult T-cell leukaemia
0.560 0.440 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.560 0.440 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.560 0.440 0.000
M35.5 Multifocal fibrosclerosis
0.560 0.440 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.560 0.440 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.555 0.444 0.000
M06.0 Seronegative rheumatoid arthritis
0.546 0.454 0.000
M40-M43 Deforming dorsopathies
0.533 0.467 0.000
E05.8 Other thyrotoxicosis
0.533 0.467 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.532 0.468 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.530 0.470 0.000
M05 Seropositive rheumatoid arthritis
0.529 0.471 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.527 0.473 0.000
C84.4 Peripheral T-cell lymphoma
0.526 0.474 0.000
M49 Spondylopathies in diseases classified elsewhere
0.525 0.475 0.000
E16 Other disorders of pancreatic internal secretion
0.524 0.476 0.000
M35.8 Other specified systemic involvement of connective tissue
0.523 0.477 0.000
M08.0 Juvenile rheumatoid arthritis
0.517 0.482 0.000
E15 Nondiabetic hypoglycaemic coma
0.516 0.484 0.000
M07.38 Other psoriatic arthropathies (Other)
0.516 0.484 0.000
M34.0 Progressive systemic sclerosis
0.515 0.484 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.515 0.485 0.000
C88.7 Other malignant immunoproliferative diseases
0.515 0.485 0.000
C88.3 Immunoproliferative small intestinal disease
0.515 0.485 0.000
C88.2 Gamma heavy chain disease
0.515 0.485 0.000
C88.1 Alpha heavy chain disease
0.515 0.485 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.514 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
M07.5 Arthropathy in ulcerative colitis
0.513 0.486 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.513 0.486 0.000
M07.2 Psoriatic spondylitis
0.513 0.486 0.000
M07.1 Arthritis mutilans
0.513 0.486 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.513 0.486 0.000
M30 Polyarteritis nodosa and related conditions
0.511 0.489 0.000
M12 Other specific arthropathies
0.508 0.492 0.000
M08.9 Juvenile arthritis, unspecified
0.507 0.493 0.000
E13.3 With ophthalmic complications
0.507 0.493 0.000
M10 Gout
0.501 0.498 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.501 0.499 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.495 0.505 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.490 0.510 0.000
M11.2 Other chondrocalcinosis
0.489 0.511 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.488 0.512 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.488 0.512 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.486 0.513 0.000
C91.7 Other lymphoid leukaemia
0.486 0.513 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.486 0.513 0.000
C91.3 Prolymphocytic leukaemia
0.486 0.513 0.000
C91.2 Subacute lymphocytic leukaemia
0.486 0.513 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.485 0.514 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.485 0.515 0.000
M02 Reactive arthropathies
0.482 0.518 0.000
C95 Leukaemia of unspecified cell type
0.481 0.519 0.000
M07.6 Other enteropathic arthropathies
0.479 0.520 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.478 0.522 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.477 0.523 0.000
C86.4 Blastic NK-cell lymphoma
0.477 0.523 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.477 0.523 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.477 0.523 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.477 0.523 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.477 0.523 0.000
M11.9 Crystal arthropathy, unspecified
0.477 0.523 0.000
C94.7 Other specified leukaemias
0.476 0.523 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.476 0.523 0.000
C94.5 Acute myelofibrosis
0.476 0.523 0.000
C94.4 Acute panmyelosis
0.476 0.523 0.000
C94.3 Mast cell leukaemia
0.476 0.523 0.000
C94.2 Acute megakaryoblastic leukaemia
0.476 0.523 0.000
C94.1 Chronic erythraemia
0.476 0.523 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.476 0.523 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.476 0.523 0.000
C96.8 Histiocytic sarcoma
0.476 0.523 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.476 0.523 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.476 0.523 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.476 0.523 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.476 0.523 0.000
C96.3 True histiocytic lymphoma
0.476 0.523 0.000
C96.2 Malignant mast cell tumour
0.476 0.523 0.000
C96.1 Malignant histiocytosis
0.476 0.523 0.000
C96.0 Letterer-Siwe disease
0.476 0.523 0.000
I73.0 Raynaud's syndrome
0.476 0.524 0.000
M35.2 Behcet's disease
0.476 0.524 0.000
E13.8 With unspecified complications
0.473 0.527 0.000
E13.7 With multiple complications
0.473 0.527 0.000
E13.6 With other specified complications
0.473 0.527 0.000
E13.5 With peripheral circulatory complications
0.473 0.527 0.000
E13.4 With neurological complications
0.473 0.527 0.000
E13.2 With renal complications
0.473 0.527 0.000
E13.1 With ketoacidosis
0.473 0.527 0.000
E13.0 With coma
0.473 0.527 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.473 0.527 0.000
E58 Dietary calcium deficiency
0.473 0.527 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.472 0.528 0.000
M31 Other necrotising vasculopathies
0.471 0.529 0.000
M33 Dermatopolymyositis
0.470 0.530 0.000
M08.8 Other juvenile arthritis
0.461 0.539 0.000
M08.4 Pauciarticular juvenile arthritis
0.461 0.539 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.461 0.539 0.000
M08.2 Juvenile arthritis with systemic onset
0.461 0.539 0.000
M08.1 Juvenile ankylosing spondylitis
0.461 0.539 0.000
M11.8 Other specified crystal arthropathies
0.461 0.539 0.000
M06.3 Rheumatoid nodule
0.460 0.540 0.000
M32.8 Other forms of systemic lupus erythematosus
0.455 0.545 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.455 0.545 0.000
M06.18 Adult-onset Still's disease (Other)
0.455 0.545 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.455 0.545 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.455 0.545 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.455 0.545 0.000
M06.14 Adult-onset Still's disease (Hand)
0.455 0.545 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.455 0.545 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.455 0.545 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.455 0.545 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.452 0.548 0.000
M11.1 Familial chondrocalcinosis
0.448 0.551 0.000
M11.0 Hydroxyapatite deposition disease
0.448 0.551 0.000
M05.8 Other seropositive rheumatoid arthritis
0.446 0.554 0.000
I73 Other peripheral vascular diseases
0.441 0.559 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.434 0.566 0.000
M46 Other inflammatory spondylopathies
0.432 0.568 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.431 0.569 0.000
M31.3 Wegener's granulomatosis
0.430 0.570 0.000
E55 Vitamin D deficiency
0.429 0.571 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.428 0.572 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.426 0.574 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.426 0.574 0.000
E63 Other nutritional deficiencies
0.426 0.574 0.000
E50 Vitamin A deficiency
0.426 0.574 0.000
E60 Dietary zinc deficiency
0.426 0.574 0.000
E59 Dietary selenium deficiency
0.426 0.574 0.000
E54 Ascorbic acid deficiency
0.426 0.574 0.000
E52 Niacin deficiency [pellagra]
0.426 0.574 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.426 0.574 0.000
M06.28 Rheumatoid bursitis (Other)
0.426 0.574 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.426 0.574 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.426 0.574 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.426 0.574 0.000
M06.24 Rheumatoid bursitis (Hand)
0.426 0.574 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.426 0.574 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.426 0.574 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.426 0.574 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.426 0.574 0.000
E51 Thiamine deficiency
0.425 0.575 0.000
C93.9 Monocytic leukaemia, unspecified
0.421 0.578 0.000
C93.7 Other monocytic leukaemia
0.421 0.578 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.421 0.578 0.000
C93.2 Subacute monocytic leukaemia
0.421 0.578 0.000
C93.0 Acute monocytic leukaemia
0.421 0.578 0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.421 0.579 0.000
E16.1 Other hypoglycaemia
0.420 0.580 0.000
M43 Other deforming dorsopathies
0.420 0.580 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.419 0.581 0.000
C91.1 Chronic lymphocytic leukaemia
0.418 0.582 0.000
M30.0 Polyarteritis nodosa
0.417 0.583 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.415 0.585 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.415 0.585 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.414 0.586 0.000
E20-E35 Disorders of other endocrine glands
0.414 0.586 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.411 0.589 0.000
M12.5 Traumatic arthropathy
0.411 0.589 0.000
E56 Other vitamin deficiencies
0.410 0.589 0.000
M08.99 Juvenile arthritis, unspecified (Site unspecified)
0.410 0.590 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.409 0.591 0.000
E45 Retarded development following protein-energy malnutrition
0.409 0.591 0.000
E43 Unspecified severe protein-energy malnutrition
0.409 0.591 0.000
E42 Marasmic kwashiorkor
0.409 0.591 0.000
E41 Nutritional marasmus
0.409 0.591 0.000
E40 Kwashiorkor
0.409 0.591 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.407 0.593 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.407 0.593 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.407 0.593 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.407 0.593 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.407 0.593 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.407 0.593 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.407 0.593 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.406 0.594 0.000
M40 Kyphosis and lordosis
0.405 0.595 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.405 0.595 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.405 0.595 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.405 0.595 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.405 0.595 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.405 0.595 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.405 0.595 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.405 0.595 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.405 0.595 0.000
M00 Pyogenic arthritis
0.405 0.595 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.404 0.596 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.402 0.598 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.401 0.598 0.000
I77 Other disorders of arteries and arterioles
0.400 0.600 0.000
K90 Intestinal malabsorption
0.400 0.600 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.399 0.600 0.000
M02.3 Reiter's disease
0.399 0.601 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.398 0.602 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.398 0.602 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.398 0.602 0.000
M09.0 Juvenile arthritis in psoriasis
0.398 0.602 0.000
M14 Arthropathies in other diseases classified elsewhere
0.397 0.602 0.001
M07.39 Other psoriatic arthropathies (Site unspecified)
0.398 0.602 0.000
M60-M63 Disorders of muscles
0.397 0.603 0.000
H40 Glaucoma
0.395 0.605 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.391 0.609 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.391 0.609 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.391 0.609 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.391 0.609 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.390 0.610 0.000
H20.9 Iridocyclitis, unspecified
0.389 0.611 0.000
H20 Iridocyclitis
0.389 0.611 0.000
I77.1 Stricture of artery
0.388 0.612 0.000
H40-H42 Glaucoma
0.386 0.614 0.000
I74 Arterial embolism and thrombosis
0.386 0.614 0.000
I78 Diseases of capillaries
0.385 0.615 0.000
M42 Spinal osteochondrosis
0.382 0.618 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.382 0.618 0.000
H40.9 Glaucoma, unspecified
0.382 0.618 0.000
H40.1 Primary open-angle glaucoma
0.381 0.619 0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)
0.380 0.620 0.000
Chapter VII Diseases of the eye and adnexa
0.380 0.620 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.379 0.621 0.000
M05.0 Felty's syndrome
0.379 0.621 0.000
M95.4 Acquired deformity of chest and rib
0.378 0.622 0.000
# Top node
0.377 0.623 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.377 0.623 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.376 0.624 0.000
M49.4 Neuropathic spondylopathy
0.376 0.624 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.376 0.624 0.000
M49.2 Enterobacterial spondylitis
0.376 0.624 0.000
M49.1 Brucella spondylitis
0.376 0.624 0.000
M49.0 Tuberculosis of spine
0.376 0.624 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.376 0.624 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.376 0.624 0.000
E16.4 Abnormal secretion of gastrin
0.376 0.624 0.000
E16.3 Increased secretion of glucagon
0.376 0.624 0.000
M05.1 Rheumatoid lung disease
0.375 0.625 0.000
M99 Biomechanical lesions, not elsewhere classified
0.373 0.627 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.373 0.627 0.000
M11.27 Other chondrocalcinosis (Ankle and foot)
0.373 0.627 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.373 0.627 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.372 0.628 0.000
M08.08 Juvenile rheumatoid arthritis (Other)
0.371 0.629 0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.371 0.629 0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.371 0.629 0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.371 0.629 0.000
M08.04 Juvenile rheumatoid arthritis (Hand)
0.371 0.629 0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.371 0.629 0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.371 0.629 0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.371 0.629 0.000
H40.5 Glaucoma secondary to other eye disorders
0.370 0.630 0.000
C92 Myeloid leukaemia
0.370 0.630 0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)
0.370 0.630 0.000
E28 Ovarian dysfunction
0.370 0.630 0.000
C91.0 Acute lymphoblastic leukaemia
0.369 0.630 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.368 0.632 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.368 0.632 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.368 0.632 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.368 0.632 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.368 0.632 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.368 0.632 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.368 0.632 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.368 0.632 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.368 0.632 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.368 0.632 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.368 0.632 0.000
M07.18 Arthritis mutilans (Other)
0.368 0.632 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.368 0.632 0.000
M07.16 Arthritis mutilans (Lower leg)
0.368 0.632 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.368 0.632 0.000
M07.14 Arthritis mutilans (Hand)
0.368 0.632 0.000
M07.13 Arthritis mutilans (Forearm)
0.368 0.632 0.000
M07.12 Arthritis mutilans (Upper arm)
0.368 0.632 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.368 0.632 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.368 0.632 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.368 0.632 0.000
M07.28 Psoriatic spondylitis (Other)
0.368 0.632 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.368 0.632 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.368 0.632 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.368 0.632 0.000
M07.24 Psoriatic spondylitis (Hand)
0.368 0.632 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.368 0.632 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.368 0.632 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.368 0.632 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.368 0.632 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.368 0.632 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.368 0.632 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.368 0.632 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.368 0.632 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.368 0.632 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.368 0.632 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.368 0.632 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.368 0.632 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.368 0.632 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.368 0.632 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.368 0.632 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.368 0.632 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.368 0.632 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.368 0.632 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.368 0.632 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.368 0.632 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.368 0.632 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.368 0.632 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.368 0.632 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.368 0.632 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.368 0.632 0.000
M02.9 Reactive arthopathy, unspecified
0.367 0.633 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.366 0.634 0.000
M30.2 Juvenile polyarteritis
0.366 0.634 0.000
M43.2 Other fusion of spine
0.365 0.635 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.364 0.636 0.000
M12.4 Intermittent hydrarthrosis
0.364 0.636 0.000
M12.1 Kaschin-Beck disease
0.364 0.636 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.364 0.636 0.000
E61 Deficiency of other nutrient elements
0.364 0.636 0.000
M08.98 Juvenile arthritis, unspecified (Other)
0.364 0.636 0.000
M08.97 Juvenile arthritis, unspecified (Ankle and foot)
0.364 0.636 0.000
M08.96 Juvenile arthritis, unspecified (Lower leg)
0.364 0.636 0.000
M08.95 Juvenile arthritis, unspecified (Pelvic region and thigh)
0.364 0.636 0.000
M08.94 Juvenile arthritis, unspecified (Hand)
0.364 0.636 0.000
M08.93 Juvenile arthritis, unspecified (Forearm)
0.364 0.636 0.000
M08.92 Juvenile arthritis, unspecified (Upper arm)
0.364 0.636 0.000
M08.91 Juvenile arthritis, unspecified (Shoulder region)
0.364 0.636 0.000
M08.90 Juvenile arthritis, unspecified (Multiple sites)
0.364 0.636 0.000
E13.9 Without complications
0.364 0.636 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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