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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3131633
log Bayes Factor = 60.4899
Chromosome 6   position 31,480,923  (GRCh37) Explore rs3131633 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
E11.9 Without complications
0.000 0.001 0.999
I20.9 Angina pectoris, unspecified
0.000 0.001 0.999
E14 Unspecified diabetes mellitus
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.008 0.992
I22 Subsequent myocardial infarction
0.000 0.009 0.991
E10.1 With ketoacidosis
0.000 0.011 0.989
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.012 0.988
E83.1 Disorders of iron metabolism
0.986 0.014 0.000
E10.4 With neurological complications
0.000 0.016 0.984
I20.0 Unstable angina
0.000 0.017 0.983
I25.5 Ischaemic cardiomyopathy
0.000 0.022 0.978
E14.9 Without complications
0.000 0.024 0.976
E14.3 With ophthalmic complications
0.000 0.026 0.974
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.026 0.974
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.030 0.970
I25.2 Old myocardial infarction
0.000 0.033 0.967
I21 Acute myocardial infarction
0.000 0.034 0.966
E70-E90 Metabolic disorders
0.000 0.035 0.964
I24 Other acute ischaemic heart diseases
0.000 0.036 0.964
G35-G37 Demyelinating diseases of the central nervous system
0.962 0.038 0.000
G37 Other demyelinating diseases of central nervous system
0.955 0.045 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.931 0.069 0.000
L40-L45 Papulosquamous disorders
0.000 0.076 0.924
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.078 0.922
E13 Other specified diabetes mellitus
0.000 0.089 0.911
I25.3 Aneurysm of heart
0.000 0.090 0.910
L43 Lichen planus
0.000 0.091 0.909
E00-E07 Disorders of thyroid gland
0.000 0.091 0.909
I10 Essential (primary) hypertension
0.000 0.095 0.905
I21.4 Acute subendocardial myocardial infarction
0.000 0.097 0.903
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.097 0.903
E03 Other hypothyroidism
0.000 0.097 0.903
E03.9 Hypothyroidism, unspecified
0.000 0.097 0.903
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.101 0.899
L43.9 Lichen planus, unspecified
0.000 0.109 0.891
I10-I15 Hypertensive diseases
0.000 0.113 0.887
E78.8 Other disorders of lipoprotein metabolism
0.000 0.113 0.887
E16 Other disorders of pancreatic internal secretion
0.000 0.116 0.884
E11.1 With ketoacidosis
0.000 0.127 0.873
E10.2 With renal complications
0.000 0.130 0.870
G37.8 Other specified demyelinating diseases of central nervous system
0.859 0.141 0.000
E11.0 With coma
0.000 0.148 0.852
I12 Hypertensive renal disease
0.000 0.149 0.851
E13.9 Without complications
0.000 0.152 0.848
E11.2 With renal complications
0.000 0.160 0.840
E16.2 Hypoglycaemia, unspecified
0.000 0.166 0.834
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.169 0.831
I24.8 Other forms of acute ischaemic heart disease
0.000 0.174 0.826
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.177 0.823
E14.4 With neurological complications
0.000 0.183 0.817
I21.9 Acute myocardial infarction, unspecified
0.000 0.192 0.808
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.193 0.807
L40.8 Other psoriasis
0.000 0.198 0.802
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.199 0.801
I12.9 Hypertensive renal disease without renal failure
0.000 0.201 0.799
I15 Secondary hypertension
0.000 0.202 0.798
E78.2 Mixed hyperlipidaemia
0.000 0.209 0.791
I23 Certain current complications following acute myocardial infarction
0.000 0.211 0.789
E10.8 With unspecified complications
0.000 0.213 0.787
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.776 0.224 0.000
E10.5 With peripheral circulatory complications
0.000 0.225 0.775
E11.6 With other specified complications
0.000 0.227 0.773
E85 Amyloidosis
0.000 0.229 0.771
L43.8 Other lichen planus
0.000 0.237 0.763
E78.1 Pure hyperglyceridaemia
0.000 0.241 0.758
E10.0 With coma
0.000 0.242 0.758
E78.5 Hyperlipidaemia, unspecified
0.000 0.247 0.753
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.256 0.744
E78.6 Lipoprotein deficiency
0.000 0.256 0.744
I12.0 Hypertensive renal disease with renal failure
0.000 0.265 0.735
E14.5 With peripheral circulatory complications
0.000 0.271 0.728
I15.1 Hypertension secondary to other renal disorders
0.000 0.275 0.725
E74 Other disorders of carbohydrate metabolism
0.000 0.278 0.722
I20.1 Angina pectoris with documented spasm
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.284 0.716
E14.7 With multiple complications
0.000 0.284 0.716
E14.2 Withrenal complications
0.000 0.284 0.716
E14.1 With ketoacidosis
0.000 0.284 0.716
E14.0 With coma
0.000 0.284 0.716
E14.6 With other specified complications
0.000 0.284 0.715
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.286 0.714
E78.3 Hyperchylomicronaemia
0.000 0.292 0.708
I22.8 Subsequent myocardial infarction of other sites
0.000 0.299 0.701
E10.6 With other specified complications
0.000 0.304 0.696
G36 Other acute disseminated demyelination
0.696 0.304 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.308 0.692
L40.0 Psoriasis vulgaris
0.000 0.308 0.692
E77 Disorders of glycoprotein metabolism
0.000 0.308 0.691
E76 Disorders of glycosaminoglycan metabolism
0.000 0.308 0.691
E72 Other disorders of amino-acid metabolism
0.000 0.308 0.691
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.308 0.691
E70 Disorders of aromatic amino-acid metabolism
0.000 0.308 0.691
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.308 0.691
E16.1 Other hypoglycaemia
0.000 0.311 0.689
G37.5 Concentric sclerosis [Balo]
0.685 0.315 0.000
G37.4 Subacute necrotising myelitis
0.685 0.315 0.000
G37.2 Central pontine myelinolysis
0.685 0.315 0.000
G37.1 Central demyelination of corpus callosum
0.685 0.315 0.000
G37.0 Diffuse sclerosis
0.685 0.315 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.331 0.669
L44 Other papulosquamous disorders
0.000 0.337 0.663
L41 Parapsoriasis
0.000 0.337 0.663
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.337 0.663
L42 Pityriasis rosea
0.000 0.338 0.662
E15 Nondiabetic hypoglycaemic coma
0.000 0.339 0.661
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.340 0.660
E13.8 With unspecified complications
0.000 0.346 0.653
E13.7 With multiple complications
0.000 0.346 0.653
E13.6 With other specified complications
0.000 0.346 0.653
E13.5 With peripheral circulatory complications
0.000 0.346 0.653
E13.4 With neurological complications
0.000 0.346 0.653
E13.3 With ophthalmic complications
0.000 0.346 0.653
E13.2 With renal complications
0.000 0.346 0.653
E13.1 With ketoacidosis
0.000 0.346 0.653
E13.0 With coma
0.000 0.346 0.653
L43.3 Subacute (active) lichen planus
0.000 0.348 0.652
L43.2 Lichenoid drug reaction
0.000 0.348 0.652
L43.1 Bullous lichen planus
0.000 0.348 0.652
L43.0 Hypertrophic lichen planus
0.000 0.348 0.652
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.348 0.652
E00 Congenital iodine-deficiency syndrome
0.000 0.348 0.652
I11 Hypertensive heart disease
0.000 0.353 0.647
E03.5 Myxoedema coma
0.000 0.353 0.647
E03.4 Atrophy of thyroid (acquired)
0.000 0.353 0.647
E03.3 Postinfectious hypothyroidism
0.000 0.353 0.647
E03.1 Congenital hypothyroidism without goitre
0.000 0.353 0.647
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.353 0.647
E11.3 With ophthalmic complications
0.000 0.353 0.647
E85.9 Amyloidosis, unspecified
0.000 0.356 0.644
E07 Other disorders of thyroid
0.000 0.357 0.643
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.359 0.641
I23.8 Other current complications following acute myocardial infarction
0.000 0.362 0.638
I13 Hypertensive heart and renal disease
0.000 0.364 0.636
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.366 0.634
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.366 0.634
E16.4 Abnormal secretion of gastrin
0.000 0.366 0.634
E16.3 Increased secretion of glucagon
0.000 0.366 0.634
E84 Cystic fibrosis
0.000 0.369 0.631
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.375 0.625
E11.5 With peripheral circulatory complications
0.000 0.378 0.622
E78.4 Other hyperlipidaemia
0.000 0.379 0.621
Chapter IX Diseases of the circulatory system
0.000 0.384 0.616
E11.4 With neurological complications
0.000 0.400 0.600
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.401 0.599
I15.9 Seconday hypertension, unspecified
0.000 0.401 0.599
E73 Lactose intolerance
0.000 0.406 0.594
E40-E46 Malnutrition
0.000 0.419 0.580
I24.1 Dressler's syndrome
0.000 0.428 0.572
I15.8 Other secondary hypertension
0.000 0.428 0.572
I15.2 Hypertension secondary to endocrine disorders
0.000 0.428 0.572
I15.0 Renovascular hypertension
0.000 0.428 0.572
E83 Disorders of mineral metabolism
0.436 0.434 0.130
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.434 0.566
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.434 0.566
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.434 0.566
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.434 0.566
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.434 0.566
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.434 0.566
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.434 0.566
E88 Other metabolic disorders
0.000 0.439 0.561
E06 Thyroiditis
0.000 0.441 0.559
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.443 0.556
E85.8 Other amyloidosis
0.000 0.447 0.553
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.447 0.553
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.447 0.553
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.447 0.553
E89.3 Postprocedural hypopituitarism
0.000 0.449 0.550
E85.4 Organ-limited amyloidosis
0.000 0.450 0.550
E05.9 Thyrotoxicosis, unspecified
0.000 0.452 0.548
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.452 0.548
I25.4 Coronary artery aneurysm
0.000 0.464 0.536
E85.3 Secondary systemic amyloidosis
0.000 0.464 0.536
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.468 0.532
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.482 0.518
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.482 0.518
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.482 0.518
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.482 0.518
E74.2 Disorders of galactose metabolism
0.000 0.482 0.518
E74.1 Disorders of fructose metabolism
0.000 0.482 0.518
E74.0 Glycogen storage disease
0.000 0.482 0.518
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E11.8 With unspecified complications
0.000 0.486 0.514
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.487 0.513
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.489 0.510
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.491 0.509
G36.0 Neuromyelitis optica [Devic]
0.505 0.494 0.000
G36.9 Acute disseminated demyelination, unspecified
0.499 0.501 0.000
G36.8 Other specified acute disseminated demyelination
0.499 0.501 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.499 0.501 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.504 0.496
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.504 0.496
E70.3 Albinism
0.000 0.504 0.496
E70.2 Disorders of tyrosine metabolism
0.000 0.504 0.496
E70.1 Other hyperphenylalaninaemias
0.000 0.504 0.496
E70.0 Classical phenylketonuria
0.000 0.504 0.496
E71.3 Disorders of fatty-acid metabolism
0.000 0.504 0.496
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.504 0.496
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.504 0.496
E71.0 Maple-syrup-urine disease
0.000 0.504 0.496
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.504 0.496
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.504 0.496
E72.5 Disorders of glycine metabolism
0.000 0.504 0.496
E72.4 Disorders of ornithine metabolism
0.000 0.504 0.496
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.504 0.496
E72.2 Disorders of urea cycle metabolism
0.000 0.504 0.496
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.504 0.496
E72.0 Disorders of amino-acid transport
0.000 0.504 0.496
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.504 0.496
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.504 0.496
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.504 0.496
E76.2 Other mucopolysaccharidoses
0.000 0.504 0.496
E76.1 Mucopolysaccharidosis, type II
0.000 0.504 0.496
E76.0 Mucopolysaccharidosis, type I
0.000 0.504 0.496
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.504 0.496
E77.8 Other disorders of glycoprotein metabolism
0.000 0.504 0.496
E77.1 Defects in glycoprotein degradation
0.000 0.504 0.496
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.504 0.496
E50-E64 Other nutritional deficiencies
0.000 0.509 0.491
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.515 0.485
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.520 0.479
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.520 0.479
E79.1 Lesch-Nyhan syndrome
0.000 0.520 0.479
E07.9 Disorder of thyroid, unspecified
0.000 0.520 0.480
L41.9 Parapsoriasis, unspecified
0.000 0.525 0.475
L41.8 Other parapsoriasis
0.000 0.525 0.475
L41.5 Retiform parapsoriasis
0.000 0.525 0.475
L41.4 Large plaque parapsoriasis
0.000 0.525 0.475
L41.3 Small plaque parapsoriasis
0.000 0.525 0.475
L41.2 Lymphomatoid papulosis
0.000 0.525 0.475
L41.1 Pityriasis lichenoides chronica
0.000 0.525 0.475
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.525 0.475
L44.9 Papulosquamous disorder, unspecified
0.000 0.525 0.475
L44.8 Other specified papulosquamous disorders
0.000 0.525 0.475
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.525 0.475
L44.3 Lichen ruber moniliformis
0.000 0.525 0.475
L44.2 Lichen striatus
0.000 0.525 0.475
L44.1 Lichen nitidus
0.000 0.525 0.475
L44.0 Pityriasis rubra pilaris
0.000 0.525 0.475
E75.6 Lipid storage disorder, unspecified
0.000 0.527 0.473
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.527 0.473
E75.3 Sphingolipidosis, unspecified
0.000 0.527 0.473
E75.2 Other sphingolipidosis
0.000 0.527 0.473
E75.1 Other gangliosidosis
0.000 0.527 0.473
E75.0 GM2 gangliosidosis
0.000 0.527 0.473
E88.2 Lipomatosis, not elsewhere classified
0.000 0.531 0.469
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.532 0.467
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.532 0.467
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.532 0.467
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.532 0.467
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.532 0.467
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.532 0.467
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.532 0.467
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.532 0.467
E07.1 Dyshormogenetic goitre
0.000 0.539 0.461
E07.0 Hypersecretion of calcitonin
0.000 0.539 0.461
E05.5 Thyroid crisis or storm
0.000 0.540 0.460
E05.4 Thyrotoxicosis factitia
0.000 0.540 0.460
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.540 0.460
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.540 0.460
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.543 0.457
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.544 0.456
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.544 0.456
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.544 0.456
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.544 0.456
E84.8 Cystic fibrosis with other manifestations
0.000 0.548 0.452
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.548 0.452
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.548 0.452
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.552 0.448
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.552 0.448
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.552 0.448
E89.5 Postprocedural testicular hypofunction
0.000 0.552 0.448
E89.1 Postprocedural hypoinsulinaemia
0.000 0.552 0.448
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.556 0.444
E75.5 Other lipid storage disorders
0.000 0.558 0.442
I00-I02 Acute rheumatic fever
0.000 0.558 0.441
E65-E68 Obesity and other hyperalimentation
0.000 0.564 0.436
M45 Ankylosing spondylitis
0.000 0.565 0.435
E07.8 Other specified disorders of thyroid
0.000 0.570 0.430
E73.8 Other lactose intolerance
0.000 0.574 0.426
E73.1 Secondary lactase deficiency
0.000 0.574 0.426
E73.0 Congenital lactase deficiency
0.000 0.574 0.426
E83.3 Disorders of phosphorus metabolism
0.384 0.578 0.038
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.580 0.420
E89.4 Postprocedural ovarian failure
0.000 0.582 0.417
E88.8 Other specified metabolic disorders
0.000 0.583 0.417
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.584 0.416
E45 Retarded development following protein-energy malnutrition
0.000 0.584 0.416
E43 Unspecified severe protein-energy malnutrition
0.000 0.584 0.416
E42 Marasmic kwashiorkor
0.000 0.584 0.416
E41 Nutritional marasmus
0.000 0.584 0.416
E40 Kwashiorkor
0.000 0.584 0.416
E89.2 Postprocedural hypoparathyroidism
0.000 0.584 0.416
E03.8 Other specified hypothyroidism
0.001 0.586 0.414
K90 Intestinal malabsorption
0.000 0.590 0.410
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.591 0.409
E83.9 Disorder of mineral metabolism, unspecified
0.313 0.594 0.093
E83.8 Other disorders of mineral metabolism
0.313 0.594 0.093
E83.2 Disorders of zinc metabolism
0.313 0.594 0.093
E83.0 Disorders of copper metabolism
0.313 0.594 0.093
E06.9 Thyroiditis, unspecified
0.000 0.596 0.404
E88.9 Metabolic disorder, unspecified
0.000 0.597 0.402
E88.3 Tumour lysis syndrome
0.000 0.597 0.402
E06.5 Other chronic thyroiditis
0.000 0.599 0.401
E06.4 Drug-induced thyroiditis
0.000 0.599 0.401
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.599 0.401
E06.1 Subacute thyroiditis
0.000 0.599 0.401
E06.0 Acute thyroiditis
0.000 0.599 0.401
E61 Deficiency of other nutrient elements
0.000 0.599 0.401
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.601 0.399
E84.9 Cystic fibrosis, unspecified
0.001 0.608 0.391
E80.6 Other disorders of bilirubin metabolism
0.000 0.614 0.386
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.625 0.375
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.628 0.371
E80.5 Crigler-Najjar syndrome
0.000 0.628 0.371
E80.3 Defects of catalase and peroxydase
0.000 0.628 0.371
E80.2 Other porphyria
0.000 0.628 0.371
E80.1 Porphyria cutanea tarda
0.000 0.628 0.371
E80.0 Hereditary erythropoietic porphyria
0.000 0.628 0.371
E05.8 Other thyrotoxicosis
0.000 0.629 0.371
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.648 0.352
E63 Other nutritional deficiencies
0.000 0.648 0.352
E56 Other vitamin deficiencies
0.000 0.648 0.352
E51 Thiamine deficiency
0.000 0.648 0.352
E50 Vitamin A deficiency
0.000 0.648 0.352
E60 Dietary zinc deficiency
0.000 0.648 0.352
E59 Dietary selenium deficiency
0.000 0.648 0.352
E58 Dietary calcium deficiency
0.000 0.648 0.352
E54 Ascorbic acid deficiency
0.000 0.648 0.352
E52 Niacin deficiency [pellagra]
0.000 0.648 0.352
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.655 0.345
E61.1 Iron deficiency
0.000 0.669 0.331
E73.9 Lactose intolerance, unspecified
0.000 0.671 0.328
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.678 0.321
I02 Rheumatic chorea
0.000 0.683 0.317
I01 Rheumatic fever with heart involvement
0.000 0.683 0.317
I00 Rheumatic fever without mention of heart involvement
0.000 0.683 0.317
E67 Other hyperalimentation
0.000 0.687 0.312
E68 Sequelae of hyperalimentation
0.000 0.687 0.312
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.688 0.312
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.688 0.312
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.688 0.312
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.688 0.312
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.688 0.312
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.688 0.312
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.688 0.312
E06.3 Autoimmune thyroiditis
0.000 0.696 0.304
E46 Unspecified protein-energy malnutrition
0.000 0.701 0.299
E44.1 Mild protein-energy malnutrition
0.000 0.701 0.298
E44.0 Moderate protein-energy malnutrition
0.000 0.701 0.298
K90.9 Intestinal malabsorption, unspecified
0.000 0.701 0.298
E61.2 Magnesium deficiency
0.000 0.704 0.296
K90.3 Pancreatic steatorrhoea
0.000 0.706 0.294
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.706 0.294
K90.1 Tropical sprue
0.000 0.706 0.294
K90.8 Other intestinal malabsorption
0.000 0.709 0.291
E61.9 Deficiency of nutrient element, unspecified
0.000 0.712 0.287
E61.8 Deficiency of other specified nutrient elements
0.000 0.712 0.287
E61.7 Deficiency of multiple nutrient elements
0.000 0.712 0.287
E61.6 Vanadium deficiency
0.000 0.712 0.287
E61.5 Molybdenum deficiency
0.000 0.712 0.287
E61.4 Chromium deficiency
0.000 0.712 0.287
E61.3 Manganese deficiency
0.000 0.712 0.287
E61.0 Copper deficiency
0.000 0.712 0.287
E65 Localised adiposity
0.000 0.719 0.281
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.722 0.278
E55 Vitamin D deficiency
0.000 0.734 0.266
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.002 0.741 0.258
E20-E35 Disorders of other endocrine glands
0.001 0.742 0.257
E50.9 Vitamin A deficiency, unspecified
0.000 0.747 0.252
E50.8 Other manifestations of vitamin A deficiency
0.000 0.747 0.252
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.747 0.252
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.747 0.252
E50.5 Vitamin A deficiency with night blindness
0.000 0.747 0.252
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.747 0.252
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.747 0.252
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.747 0.252
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.747 0.252
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.747 0.252
E51.9 Thiamine deficiency, unspecified
0.000 0.747 0.252
E51.8 Other manifestations of thiamine deficiency
0.000 0.747 0.252
E51.2 Wernicke's encephalopathy
0.000 0.747 0.252
E51.1 Beriberi
0.000 0.747 0.252
E56.9 Vitamin deficiency, unspecified
0.000 0.747 0.252
E56.8 Deficiency of other vitamins
0.000 0.747 0.252
E56.1 Deficiency of vitamin K
0.000 0.747 0.252
E56.0 Deficiency of vitamin E
0.000 0.747 0.252
E63.9 Nutritional deficiency, unspecified
0.000 0.747 0.252
E63.8 Other specified nutritional deficiencies
0.000 0.747 0.252
E63.1 Imbalance of constituents of food intake
0.000 0.747 0.252
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.747 0.252
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.747 0.252
E64.8 Sequelae of other nutritional deficiencies
0.000 0.747 0.252
E64.3 Sequelae of rickets
0.000 0.747 0.252
E64.2 Sequelae of vitamin C deficiency
0.000 0.747 0.252
E64.1 Sequelae of vitamin A deficiency
0.000 0.747 0.252
E64.0 Sequelae of protein-energy malnutrition
0.000 0.747 0.252
R07.4 Chest pain, unspecified
0.000 0.768 0.232
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.773 0.227
I01.8 Other acute rheumatic heart disease
0.000 0.773 0.227
I01.2 Acute rheumatic myocarditis
0.000 0.773 0.227
I01.1 Acute rheumatic endocarditis
0.000 0.773 0.227
I01.0 Acute rheumatic pericarditis
0.000 0.773 0.227
I02.9 Rheumatic chorea without heart involvement
0.000 0.773 0.227
I02.0 Rheumatic chorea with heart involvement
0.000 0.773 0.227
E67.8 Other specified hyperalimentation
0.000 0.776 0.224
E67.3 Hypervitaminosis D
0.000 0.776 0.224
E67.2 Megavitamin-B6 syndrome
0.000 0.776 0.224
E67.1 Hypercarotenaemia
0.000 0.776 0.224
E67.0 Hypervitaminosis A
0.000 0.776 0.224
E83.4 Disorders of magnesium metabolism
0.133 0.777 0.090
E22 Hyperfunction of pituitary gland
0.000 0.778 0.222
E23 Hypofunction and other disorders of pituitary gland
0.000 0.787 0.213
E89.0 Postprocedural hypothyroidism
0.000 0.790 0.210
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.801 0.199
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.802 0.198
I05-I09 Chronic rheumatic heart diseases
0.000 0.802 0.198
E29 Testicular dysfunction
0.000 0.804 0.195
E55.0 Rickets, active
0.000 0.809 0.191
I28 Other diseases of pulmonary vessels
0.001 0.813 0.186
E35 Disorders of endocrine glands in diseases classified elsewhere
0.001 0.815 0.184
E32 Diseases of thymus
0.001 0.815 0.184
E31 Polyglandular dysfunction
0.001 0.815 0.184
E30 Disorders of puberty, not elsewhere classified
0.001 0.815 0.184
E83.5 Disorders of calcium metabolism
0.158 0.816 0.025
E23.6 Other disorders of pituitary gland
0.000 0.818 0.182
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.821 0.179
E20 Hypoparathyroidism
0.001 0.829 0.171
E23.2 Diabetes insipidus
0.000 0.829 0.171
E28 Ovarian dysfunction
0.000 0.830 0.170
E24 Cushing's syndrome
0.001 0.831 0.169
E26 Hyperaldosteronism
0.001 0.836 0.163
E22.1 Hyperprolactinaemia
0.000 0.837 0.163
E80.4 Gilbert's syndrome
0.000 0.837 0.162
E53 Deficiency of other B group vitamins
0.001 0.838 0.161
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.841 0.159
E22.8 Other hyperfunction of pituitary gland
0.000 0.841 0.159
I27 Other pulmonary heart diseases
0.001 0.842 0.157
E25 Adrenogenital disorders
0.001 0.842 0.157
E23.7 Disorder of pituitary gland, unspecified
0.000 0.846 0.154
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.847 0.153
E23.1 Drug-induced hypopituitarism
0.000 0.847 0.153
E29.1 Testicular hypofunction
0.000 0.849 0.151
E22.0 Acromegaly and pituitary gigantism
0.000 0.851 0.149
E29.9 Testicular dysfunction, unspecified
0.000 0.859 0.140
E29.8 Other testicular dysfunction
0.000 0.859 0.140
E29.0 Testicular hyperfunction
0.000 0.859 0.140
I09 Other rheumatic heart diseases
0.000 0.859 0.140
I28.8 Other specified diseases of pulmonary vessels
0.001 0.864 0.135
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.865 0.133
I28.1 Aneurysm of pulmonary artery
0.001 0.865 0.133
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.865 0.133
E34 Other endocrine disorders
0.001 0.866 0.133
I06 Rheumatic aortic valve diseases
0.000 0.867 0.133
E30.9 Disorder of puberty, unspecified
0.001 0.867 0.132
E30.8 Other disorders of puberty
0.001 0.867 0.132
E30.1 Precocious puberty
0.001 0.867 0.132
E30.0 Delayed puberty
0.001 0.867 0.132
E31.9 Polyglandular dysfunction, unspecified
0.001 0.867 0.132
E31.8 Other polyglandular dysfunction
0.001 0.867 0.132
E31.1 Polyglandular hyperfunction
0.001 0.867 0.132
E31.0 Autoimmune polyglandular failure
0.001 0.867 0.132
E32.9 Disease of thymus, unspecified
0.001 0.867 0.132
E32.8 Other diseases of thymus
0.001 0.867 0.132
E32.1 Abscess of thymus
0.001 0.867 0.132
E32.0 Persistent hyperplasia of thymus
0.001 0.867 0.132
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.001 0.867 0.132
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.001 0.867 0.132
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.001 0.867 0.132

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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