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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3131638
log Bayes Factor = 73.433
Chromosome 6   position 31,475,127  (GRCh37) Explore rs3131638 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40 Psoriasis
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.001 0.999
I10-I15 Hypertensive diseases
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
I24 Other acute ischaemic heart diseases
0.000 0.003 0.997
I20 Angina pectoris
0.000 0.004 0.996
E14.3 With ophthalmic complications
0.000 0.005 0.995
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.005 0.995
I20.9 Angina pectoris, unspecified
0.000 0.006 0.994
E14.9 Without complications
0.000 0.007 0.993
E00-E07 Disorders of thyroid gland
0.000 0.008 0.992
E10.1 With ketoacidosis
0.000 0.008 0.992
Chapter IX Diseases of the circulatory system
0.000 0.009 0.991
E03 Other hypothyroidism
0.000 0.010 0.990
E03.9 Hypothyroidism, unspecified
0.000 0.011 0.989
M45 Ankylosing spondylitis
0.000 0.012 0.988
J45.9 Asthma, unspecified
0.000 0.012 0.988
G35-G37 Demyelinating diseases of the central nervous system
0.984 0.016 0.000
E10.4 With neurological complications
0.000 0.016 0.984
G37 Other demyelinating diseases of central nervous system
0.981 0.019 0.000
L40-L45 Papulosquamous disorders
0.000 0.021 0.979
E78.0 Pure hypercholesterolaemia
0.000 0.022 0.978
E83.1 Disorders of iron metabolism
0.977 0.023 0.000
I25.2 Old myocardial infarction
0.000 0.026 0.974
G37.9 Demyelinating disease of central nervous system, unspecified
0.973 0.027 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.029 0.971
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.030 0.970
I24.8 Other forms of acute ischaemic heart disease
0.000 0.032 0.968
E70-E90 Metabolic disorders
0.000 0.032 0.968
I22 Subsequent myocardial infarction
0.000 0.036 0.964
M75.0 Adhesive capsulitis of shoulder
0.000 0.039 0.961
M75 Shoulder lesions
0.000 0.039 0.961
I25.5 Ischaemic cardiomyopathy
0.000 0.042 0.958
M75.4 Impingement syndrome of shoulder
0.000 0.047 0.953
M70-M79 Other soft tissue disorders
0.000 0.051 0.949
I12 Hypertensive renal disease
0.000 0.059 0.941
# Top node
0.000 0.059 0.941
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.060 0.939
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.061 0.939
Chapter VIII Diseases of the ear and mastoid process
0.000 0.063 0.937
H65-H75 Diseases of middle ear and mastoid
0.000 0.064 0.936
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.064 0.936
M45-M49 Spondylopathies
0.000 0.068 0.932
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.069 0.931
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.071 0.929
H66 Suppurative and unspecified otitis media
0.000 0.076 0.924
H66.3 Other chronic suppurative otitis media
0.000 0.077 0.923
H71 Cholesteatoma of middle ear
0.000 0.080 0.920
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.081 0.919
L43 Lichen planus
0.000 0.090 0.910
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.094 0.906
I15 Secondary hypertension
0.000 0.096 0.904
K90 Intestinal malabsorption
0.000 0.098 0.902
I12.9 Hypertensive renal disease without renal failure
0.000 0.105 0.895
G37.8 Other specified demyelinating diseases of central nervous system
0.895 0.105 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.106 0.894
E11.1 With ketoacidosis
0.000 0.110 0.890
E13 Other specified diabetes mellitus
0.000 0.119 0.881
I20.0 Unstable angina
0.000 0.123 0.877
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.124 0.876
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.125 0.875
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.134 0.866
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.134 0.866
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.141 0.859
E10.2 With renal complications
0.000 0.146 0.854
M79.6 Pain in limb
0.000 0.151 0.849
E05.9 Thyrotoxicosis, unspecified
0.000 0.151 0.849
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.152 0.848
E78.8 Other disorders of lipoprotein metabolism
0.000 0.153 0.847
L40.8 Other psoriasis
0.000 0.158 0.842
K90-K93 Other diseases of the digestive system
0.000 0.158 0.842
E16 Other disorders of pancreatic internal secretion
0.000 0.161 0.839
Chapter XI Diseases of the digestive system
0.000 0.161 0.839
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.162 0.838
L43.9 Lichen planus, unspecified
0.000 0.167 0.833
M75.2 Bicipital tendinitis
0.000 0.171 0.829
E10.8 With unspecified complications
0.000 0.173 0.827
E85 Amyloidosis
0.000 0.182 0.818
E78.2 Mixed hyperlipidaemia
0.000 0.188 0.812
I15.1 Hypertension secondary to other renal disorders
0.000 0.193 0.807
E11.0 With coma
0.000 0.195 0.805
I25.3 Aneurysm of heart
0.000 0.195 0.805
H73 Other disorders of tympanic membrane
0.000 0.196 0.804
K50-K52 Noninfective enteritis and colitis
0.000 0.197 0.803
K52 Other non-infective gastro-enteritis and colitis
0.000 0.197 0.803
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.200 0.800
H60-H62 Diseases of external ear
0.000 0.200 0.800
I23 Certain current complications following acute myocardial infarction
0.000 0.201 0.799
E10.5 With peripheral circulatory complications
0.000 0.204 0.796
E13.9 Without complications
0.000 0.204 0.796
E10.0 With coma
0.000 0.204 0.796
H74 Other disorders of middle ear and mastoid
0.000 0.205 0.795
E11.2 With renal complications
0.000 0.211 0.789
E14.8 With unspecified complications
0.000 0.218 0.782
E11.6 With other specified complications
0.000 0.222 0.778
M79.60 Pain in limb (Multiple sites)
0.000 0.224 0.776
E11.3 With ophthalmic complications
0.000 0.231 0.769
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.232 0.768
M70.6 Trochanteric bursitis
0.000 0.244 0.756
M79.62 Pain in limb (Upper arm)
0.000 0.245 0.755
E14.6 With other specified complications
0.000 0.248 0.752
M70.4 Prepatellar bursitis
0.000 0.252 0.748
E14.1 With ketoacidosis
0.000 0.252 0.748
E16.2 Hypoglycaemia, unspecified
0.000 0.252 0.748
I84.9 Unspecified haemorrhoids without complication
0.000 0.252 0.748
M79.63 Pain in limb (Forearm)
0.000 0.253 0.747
L43.8 Other lichen planus
0.000 0.257 0.743
E78.1 Pure hyperglyceridaemia
0.000 0.258 0.742
E14.4 With neurological complications
0.000 0.263 0.737
E83 Disorders of mineral metabolism
0.688 0.267 0.045
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.729 0.271 0.000
K70-K77 Diseases of liver
0.000 0.272 0.728
I15.9 Seconday hypertension, unspecified
0.000 0.272 0.728
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.275 0.725
E74 Other disorders of carbohydrate metabolism
0.000 0.282 0.717
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.284 0.715
L42 Pityriasis rosea
0.000 0.285 0.715
I84 Haemorrhoids
0.000 0.287 0.713
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.288 0.711
E00 Congenital iodine-deficiency syndrome
0.000 0.288 0.711
I00-I02 Acute rheumatic fever
0.000 0.289 0.711
G36 Other acute disseminated demyelination
0.710 0.290 0.000
E03.5 Myxoedema coma
0.000 0.290 0.709
E03.4 Atrophy of thyroid (acquired)
0.000 0.290 0.709
E03.3 Postinfectious hypothyroidism
0.000 0.290 0.709
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.290 0.709
E14.5 With peripheral circulatory complications
0.000 0.291 0.709
I11 Hypertensive heart disease
0.000 0.291 0.709
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.291 0.709
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.291 0.709
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.291 0.709
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.291 0.709
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.291 0.709
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.291 0.709
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.291 0.709
E78.6 Lipoprotein deficiency
0.000 0.292 0.708
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.293 0.707
E10.6 With other specified complications
0.000 0.294 0.706
E85.9 Amyloidosis, unspecified
0.000 0.294 0.706
I12.0 Hypertensive renal disease with renal failure
0.000 0.295 0.705
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.296 0.703
G37.5 Concentric sclerosis [Balo]
0.703 0.296 0.000
G37.4 Subacute necrotising myelitis
0.703 0.296 0.000
G37.2 Central pontine myelinolysis
0.703 0.296 0.000
G37.1 Central demyelination of corpus callosum
0.703 0.296 0.000
G37.0 Diffuse sclerosis
0.703 0.296 0.000
L44 Other papulosquamous disorders
0.000 0.298 0.702
L41 Parapsoriasis
0.000 0.298 0.702
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.298 0.702
H66.4 Suppurative otitis media, unspecified
0.000 0.300 0.699
E78.3 Hyperchylomicronaemia
0.000 0.304 0.696
M79.7 Fibromyalgia
0.000 0.304 0.696
K74 Fibrosis and cirrhosis of liver
0.000 0.305 0.695
E77 Disorders of glycoprotein metabolism
0.000 0.306 0.694
E76 Disorders of glycosaminoglycan metabolism
0.000 0.306 0.694
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.306 0.694
E70 Disorders of aromatic amino-acid metabolism
0.000 0.306 0.694
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.306 0.694
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.309 0.691
H73.8 Other specified disorders of tympanic membrane
0.000 0.309 0.690
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.310 0.690
M75.8 Other shoulder lesions
0.000 0.311 0.689
M76 Enthesopathies of lower limb, excluding foot
0.000 0.312 0.688
K55-K64 Other diseases of intestines
0.000 0.313 0.687
K58 Irritable bowel syndrome
0.000 0.316 0.684
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.318 0.682
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.320 0.680
K60 Fissure and fistula of anal and rectal regions
0.000 0.320 0.680
K60.2 Anal fissure, unspecified
0.000 0.321 0.679
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.323 0.677
H74.4 Polyp of middle ear
0.000 0.324 0.676
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.324 0.676
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.325 0.675
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.326 0.674
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.327 0.673
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.328 0.672
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.328 0.672
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.329 0.671
H68 Eustachian salpingitis and obstruction
0.000 0.329 0.671
H67 Otitis media in diseases classified elsewhere
0.000 0.329 0.671
E05.5 Thyroid crisis or storm
0.000 0.329 0.671
E05.4 Thyrotoxicosis factitia
0.000 0.329 0.671
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.329 0.671
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.329 0.671
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.330 0.670
E03.1 Congenital hypothyroidism without goitre
0.000 0.333 0.667
H60 Otitis externa
0.000 0.334 0.666
H90-H95 Other disorders of ear
0.000 0.335 0.665
E83.3 Disorders of phosphorus metabolism
0.655 0.337 0.008
K90.8 Other intestinal malabsorption
0.000 0.338 0.662
E79 Disorders of purine and pyrimidine metabolism
0.000 0.342 0.657
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.343 0.657
E11.4 With neurological complications
0.000 0.343 0.657
M79.1 Myalgia
0.000 0.344 0.656
M49 Spondylopathies in diseases classified elsewhere
0.000 0.344 0.656
I23.8 Other current complications following acute myocardial infarction
0.000 0.344 0.655
H66.0 Acute suppurative otitis media
0.000 0.345 0.655
L43.3 Subacute (active) lichen planus
0.000 0.348 0.652
L43.2 Lichenoid drug reaction
0.000 0.348 0.652
L43.1 Bullous lichen planus
0.000 0.348 0.652
L43.0 Hypertrophic lichen planus
0.000 0.348 0.652
E72 Other disorders of amino-acid metabolism
0.000 0.348 0.652
K52.1 Toxic gastro-enteritis and colitis
0.000 0.348 0.652
E07 Other disorders of thyroid
0.000 0.348 0.651
I86 Varicose veins of other sites
0.000 0.349 0.651
I15.0 Renovascular hypertension
0.000 0.350 0.650
E15 Nondiabetic hypoglycaemic coma
0.000 0.350 0.649
I15.8 Other secondary hypertension
0.000 0.351 0.648
I15.2 Hypertension secondary to endocrine disorders
0.000 0.351 0.648
K90.3 Pancreatic steatorrhoea
0.000 0.353 0.646
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.353 0.646
K90.1 Tropical sprue
0.000 0.353 0.646
I84.6 Residual haemorrhoidal skin tags
0.000 0.354 0.646
E16.1 Other hypoglycaemia
0.000 0.360 0.639
E88 Other metabolic disorders
0.000 0.362 0.637
L40.0 Psoriasis vulgaris
0.000 0.364 0.636
M79.2 Neuralgia and neuritis, unspecified
0.000 0.365 0.635
H61 Other disorders of external ear
0.000 0.365 0.635
E84 Cystic fibrosis
0.000 0.365 0.634
E13.8 With unspecified complications
0.000 0.368 0.632
E13.7 With multiple complications
0.000 0.368 0.632
E13.6 With other specified complications
0.000 0.368 0.632
E13.5 With peripheral circulatory complications
0.000 0.368 0.632
E13.4 With neurological complications
0.000 0.368 0.632
E13.3 With ophthalmic complications
0.000 0.368 0.632
E13.2 With renal complications
0.000 0.368 0.632
E13.1 With ketoacidosis
0.000 0.368 0.632
E13.0 With coma
0.000 0.368 0.632
I22.8 Subsequent myocardial infarction of other sites
0.000 0.368 0.632
L10-L14 Bullous disorders
0.000 0.368 0.632
K74.3 Primary biliary cirrhosis
0.000 0.369 0.631
L50-L54 Urticaria and erythema
0.000 0.370 0.630
H70 Mastoiditis and related conditions
0.000 0.371 0.628
I87 Other disorders of veins
0.000 0.374 0.626
K72 Hepatic failure, not elsewhere classified
0.000 0.374 0.626
K74.5 Biliary cirrhosis, unspecified
0.000 0.377 0.623
M75.3 Calcific tendinitis of shoulder
0.000 0.379 0.621
K58.9 Irritable bowel syndrome without diarrhoea
0.000 0.379 0.621
M79.3 Panniculitis, unspecified
0.000 0.379 0.621
I24.1 Dressler's syndrome
0.000 0.385 0.614
K60.5 Anorectal fistula
0.000 0.390 0.610
M79.9 Soft tissue disorder, unspecified
0.000 0.391 0.609
E89.3 Postprocedural hypopituitarism
0.000 0.391 0.609
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.392 0.608
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.392 0.608
M70.1 Bursitis of hand
0.000 0.392 0.608
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.392 0.608
K73 Chronic hepatitis, not elsewhere classified
0.000 0.393 0.607
E85.3 Secondary systemic amyloidosis
0.000 0.395 0.605
M70.2 Olecranon bursitis
0.000 0.395 0.605
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.396 0.604
E73 Lactose intolerance
0.000 0.396 0.603
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.398 0.602
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.398 0.602
E16.4 Abnormal secretion of gastrin
0.000 0.398 0.602
E16.3 Increased secretion of glucagon
0.000 0.398 0.602
I86.4 Gastric varices
0.000 0.400 0.600
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.402 0.598
H90 Conductive and sensorineural hearing loss
0.000 0.402 0.598
E78.5 Hyperlipidaemia, unspecified
0.000 0.403 0.597
E40-E46 Malnutrition
0.000 0.403 0.597
E65-E68 Obesity and other hyperalimentation
0.000 0.403 0.597
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.403 0.597
M71 Other bursopathies
0.000 0.405 0.595
M91-M94 Chondropathies
0.000 0.406 0.594
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.409 0.591
M46 Other inflammatory spondylopathies
0.000 0.411 0.589
E85.8 Other amyloidosis
0.000 0.413 0.586
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.413 0.586
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.413 0.586
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.413 0.586
I25.4 Coronary artery aneurysm
0.000 0.416 0.584
E06 Thyroiditis
0.000 0.417 0.583
H60.3 Other infective otitis externa
0.000 0.418 0.582
M79.79 Fibromyalgia (Site unspecified)
0.000 0.419 0.581
M79.67 Pain in limb (Ankle and foot)
0.000 0.419 0.581
E85.4 Organ-limited amyloidosis
0.000 0.423 0.577
H73.0 Acute myringitis
0.000 0.423 0.577
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.423 0.576
H61.1 Non-infective disorders of pinna
0.000 0.426 0.574
M79.4 Hypertrophy of (infrapatellar) fat pad
0.000 0.426 0.574
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.426 0.574
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.427 0.573
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.427 0.573
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.427 0.573
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.427 0.573
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.427 0.573
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.427 0.573
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.427 0.573
I21 Acute myocardial infarction
0.000 0.428 0.572
E50-E64 Other nutritional deficiencies
0.000 0.430 0.570
K90.9 Intestinal malabsorption, unspecified
0.000 0.432 0.568
M75.9 Shoulder lesion, unspecified
0.000 0.434 0.566
M70.5 Other bursitis of knee
0.000 0.437 0.563
M70.3 Other bursitis of elbow
0.000 0.439 0.561
M00-M03 Infectious arthropathies
0.000 0.439 0.561
M77 Other enthesopathies
0.000 0.439 0.561
E88.2 Lipomatosis, not elsewhere classified
0.000 0.440 0.559
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.442 0.558
H36.0 Diabetic retinopathy
0.000 0.444 0.556
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.447 0.553
K72.9 Hepatic failure, unspecified
0.000 0.451 0.549
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.453 0.547
M79.19 Myalgia (Site unspecified)
0.000 0.453 0.547
K60.0 Acute anal fissure
0.000 0.455 0.545
K75 Other inflammatory liver diseases
0.000 0.456 0.544
H60.5 Acute otitis externa, non-infective
0.000 0.456 0.543
M70.69 Trochanteric bursitis-Site unspec
0.000 0.458 0.542
M70.68 Trochanteric bursitis-Other
0.000 0.458 0.542
M70.67 Trochanteric bursitis-Ankle/Foot
0.000 0.458 0.542
M70.66 Trochanteric bursitis-Lower Leg
0.000 0.458 0.542
M70.64 Trochanteric bursitis-Hand
0.000 0.458 0.542
M70.63 Trochanteric bursitis-Forearm
0.000 0.458 0.542
M70.62 Trochanteric bursitis-Upper arm
0.000 0.458 0.542
M70.61 Trochanteric bursitis-Shldr region
0.000 0.458 0.542
M70.60 Trochanteric bursitis-Mult sites
0.000 0.458 0.542
E11.5 With peripheral circulatory complications
0.000 0.459 0.541
K60.4 Rectal fistula
0.000 0.460 0.540
H36 Retinal disorders in diseases classified elsewhere
0.000 0.460 0.540
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.000 0.460 0.540
M70.7 Other bursitis of hip
0.000 0.461 0.539
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.462 0.538
M70.49 Prepatellar bursitis-Site unspec
0.000 0.464 0.536
M70.48 Prepatellar bursitis-Other
0.000 0.464 0.536
M70.47 Prepatellar bursitis-Ankle/Foot
0.000 0.464 0.536
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.000 0.464 0.536
M70.44 Prepatellar bursitis-Hand
0.000 0.464 0.536
M70.43 Prepatellar bursitis-Forearm
0.000 0.464 0.536
M70.42 Prepatellar bursitis-Upper arm
0.000 0.464 0.536
M70.41 Prepatellar bursitis-Shldr region
0.000 0.464 0.536
M70.40 Prepatellar bursitis-Mult sites
0.000 0.464 0.536
I20.1 Angina pectoris with documented spasm
0.000 0.465 0.535
M76.6 Achilles tendinitis
0.000 0.465 0.535
M79.68 Pain in limb (Other)
0.000 0.466 0.533
K73.9 Chronic hepatitis, unspecified
0.000 0.467 0.533
H90.5 Sensorineural hearing loss, unspecified
0.000 0.469 0.531
K74.6 Other and unspecified cirrhosis of liver
0.000 0.471 0.529
M75.5 Bursitis of shoulder
0.000 0.471 0.529
H30-H36 Disorders of choroid and retina
0.000 0.471 0.529
I84.3 External thrombosed haemorrhoids
0.000 0.471 0.529
H61.9 Disorder of external ear, unspecified
0.000 0.472 0.528
M79.16 Myalgia (Lower leg)
0.000 0.472 0.528
E83.9 Disorder of mineral metabolism, unspecified
0.493 0.474 0.033
E83.8 Other disorders of mineral metabolism
0.493 0.474 0.033
E83.2 Disorders of zinc metabolism
0.493 0.474 0.033
E83.0 Disorders of copper metabolism
0.493 0.474 0.033
H90.2 Conductive hearing loss, unspecified
0.000 0.476 0.524
I86.8 Varicose veins of other specified sites
0.000 0.476 0.524
K77 Liver disorders in diseases classified elsewhere
0.000 0.478 0.522
K71 Toxic liver disease
0.000 0.478 0.522
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.478 0.522
H35 Other retinal disorders
0.000 0.480 0.520
M79.11 Myalgia (Shoulder region)
0.000 0.484 0.516
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.485 0.514
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.485 0.514
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.485 0.514
E74.2 Disorders of galactose metabolism
0.000 0.485 0.514
E74.1 Disorders of fructose metabolism
0.000 0.485 0.514
E74.0 Glycogen storage disease
0.000 0.485 0.514
H92 Otalgia and effusion of ear
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G36.0 Neuromyelitis optica [Devic]
0.514 0.486 0.000
E05.8 Other thyrotoxicosis
0.000 0.486 0.513
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.487 0.513
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.487 0.513
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.487 0.513
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.487 0.513
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.489 0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.490 0.510
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.490 0.510
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.490 0.510
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.490 0.510
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.490 0.510
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.490 0.510
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.490 0.510
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.490 0.510
I02 Rheumatic chorea
0.000 0.490 0.509
I01 Rheumatic fever with heart involvement
0.000 0.490 0.509
I00 Rheumatic fever without mention of heart involvement
0.000 0.490 0.509
G36.9 Acute disseminated demyelination, unspecified
0.509 0.491 0.000
G36.8 Other specified acute disseminated demyelination
0.509 0.491 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.509 0.491 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.000 0.491 0.509
H72 Perforation of tympanic membrane
0.000 0.492 0.508
Chapter VII Diseases of the eye and adnexa
0.000 0.494 0.506
L41.9 Parapsoriasis, unspecified
0.000 0.496 0.503
L41.8 Other parapsoriasis
0.000 0.496 0.503
L41.5 Retiform parapsoriasis
0.000 0.496 0.503
L41.4 Large plaque parapsoriasis
0.000 0.496 0.503
L41.3 Small plaque parapsoriasis
0.000 0.496 0.503
L41.2 Lymphomatoid papulosis
0.000 0.496 0.503
L41.1 Pityriasis lichenoides chronica
0.000 0.496 0.503
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.496 0.503
L44.9 Papulosquamous disorder, unspecified
0.000 0.496 0.503
L44.8 Other specified papulosquamous disorders
0.000 0.496 0.503
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.496 0.503
L44.3 Lichen ruber moniliformis
0.000 0.496 0.503
L44.2 Lichen striatus
0.000 0.496 0.503
L44.1 Lichen nitidus
0.000 0.496 0.503
L44.0 Pityriasis rubra pilaris
0.000 0.496 0.503
H35.8 Other specified retinal disorders
0.000 0.497 0.503
I87.1 Compression of vein
0.000 0.498 0.502
E78.4 Other hyperlipidaemia
0.000 0.499 0.501
H61.3 Acquired stenosis of external ear canal
0.000 0.499 0.501
I84.1 Internal haemorrhoids with other complications
0.000 0.500 0.500
M79.78 Fibromyalgia (Other)
0.000 0.501 0.499
M79.77 Fibromyalgia (Ankle and foot)
0.000 0.501 0.499
M79.76 Fibromyalgia (Lower leg)
0.000 0.501 0.499
M79.75 Fibromyalgia (Pelvic region and thigh)
0.000 0.501 0.499
M79.74 Fibromyalgia (Hand)
0.000 0.501 0.499
M79.73 Fibromyalgia (Forearm)
0.000 0.501 0.499
M79.72 Fibromyalgia (Upper arm)
0.000 0.501 0.499
M79.71 Fibromyalgia (Shoulder region)
0.000 0.501 0.499
K74.4 Secondary biliary cirrhosis
0.000 0.502 0.498
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.502 0.498
K74.1 Hepatic sclerosis
0.000 0.502 0.498
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.502 0.497
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.502 0.497
E70.3 Albinism
0.000 0.502 0.497
E70.2 Disorders of tyrosine metabolism
0.000 0.502 0.497
E70.1 Other hyperphenylalaninaemias
0.000 0.502 0.497
E70.0 Classical phenylketonuria
0.000 0.502 0.497
E71.3 Disorders of fatty-acid metabolism
0.000 0.502 0.497
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.502 0.497
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.502 0.497
E71.0 Maple-syrup-urine disease
0.000 0.502 0.497
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.502 0.497
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.502 0.497
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.502 0.497
E76.2 Other mucopolysaccharidoses
0.000 0.502 0.497
E76.1 Mucopolysaccharidosis, type II
0.000 0.502 0.497
E76.0 Mucopolysaccharidosis, type I
0.000 0.502 0.497
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.502 0.497
E77.8 Other disorders of glycoprotein metabolism
0.000 0.502 0.497
E77.1 Defects in glycoprotein degradation
0.000 0.502 0.497
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.502 0.497
I86.2 Pelvic varices
0.000 0.504 0.496
H60.8 Other otitis externa
0.000 0.505 0.495
I21.4 Acute subendocardial myocardial infarction
0.000 0.505 0.495
M75.81 Other shoulder lesions, right shoulder
0.000 0.506 0.494
M79.28 Neuralgia and neuritis, unspecified (Other)
0.000 0.506 0.493
M86-M90 Other osteopathies
0.000 0.507 0.493
M76.9 Enthesopathy of lower limb, unspecified
0.000 0.507 0.493
M76.7 Peroneal tendinitis
0.000 0.507 0.493
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]
0.000 0.507 0.493
M76.3 Iliotibial band syndrome
0.000 0.507 0.493
M76.2 Iliac crest spur
0.000 0.507 0.493
M76.1 Psoas tendinitis
0.000 0.507 0.493
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.507 0.493
M79.5 Residual foreign body in soft tissue
0.000 0.508 0.492
E75.6 Lipid storage disorder, unspecified
0.000 0.511 0.489
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.511 0.489
E75.3 Sphingolipidosis, unspecified
0.000 0.511 0.489
E75.2 Other sphingolipidosis
0.000 0.511 0.489
E75.1 Other gangliosidosis
0.000 0.511 0.489
E75.0 GM2 gangliosidosis
0.000 0.511 0.489
M73.8 Other soft tissue disorders in diseases classified elsewhere
0.000 0.512 0.488
M73.1 Syphilitic bursitis
0.000 0.512 0.488
M73.0 Gonococcal bursitis
0.000 0.512 0.488
L13 Other bullous disorders
0.000 0.513 0.487
L52 Erythema nodosum
0.000 0.513 0.487
M79.70 Fibromyalgia (Multiple sites)
0.000 0.514 0.486
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.516 0.484
P90-P96 Other disorders originating in the perinatal period
0.000 0.516 0.483
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.516 0.483
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.516 0.483

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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