TreeWAS – Variant ID: rs3131888

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K51 Ulcerative colitis	0.000	0.002	0.998
L40.5 Arthropathic psoriasis	0.994	0.006	0.000
L40 Psoriasis	0.993	0.007	0.000
L40.9 Psoriasis, unspecified	0.993	0.007	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.024	0.976
K51.4 Pseudopolyposis of colon	0.000	0.036	0.964
R31 Unspecified haematuria	0.000	0.037	0.963
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.050	0.950
K51.8 Other ulcerative colitis	0.000	0.124	0.876
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.863	0.137	0.000
N13 Obstructive and reflux uropathy	0.853	0.147	0.000
L40.0 Psoriasis vulgaris	0.836	0.164	0.000
L40.8 Other psoriasis	0.832	0.168	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.824	0.176	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.795	0.205	0.000
L40.1 Generalised pustular psoriasis	0.789	0.211	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.781	0.219	0.000
L40.3 Pustulosis palmaris et plantaris	0.753	0.247	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.739	0.261	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.264	0.736
L40.2 Acrodermatitis continua	0.712	0.288	0.000
K51.5 Mucosal proctocolitis	0.000	0.315	0.685
N13.6 Pyonephrosis	0.679	0.321	0.000
L40.4 Guttate psoriasis	0.629	0.370	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.379	0.621
K90 Intestinal malabsorption	0.610	0.390	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.527	0.473	0.000
N13.4 Hydroureter	0.518	0.482	0.000
E05.9 Thyrotoxicosis, unspecified	0.514	0.486	0.000
K90.9 Intestinal malabsorption, unspecified	0.508	0.492	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.508	0.492	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.499	0.501	0.000
K90.8 Other intestinal malabsorption	0.470	0.530	0.000
N13.3 Other and unspecified hydronephrosis	0.468	0.532	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.441	0.559	0.000
K90.3 Pancreatic steatorrhoea	0.438	0.562	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.438	0.562	0.000
K90.1 Tropical sprue	0.438	0.562	0.000
E05.8 Other thyrotoxicosis	0.430	0.570	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.425	0.575	0.000
N13.8 Other obstructive and reflux uropathy	0.425	0.575	0.000
N10-N16 Renal tubulo-interstitial diseases	0.368	0.632	0.000
E05.5 Thyroid crisis or storm	0.364	0.636	0.000
E05.4 Thyrotoxicosis factitia	0.364	0.636	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.364	0.636	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.362	0.638	0.000
N11 Chronic tubulo-interstitial nephritis	0.348	0.652	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.673	0.327
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.307	0.693	0.000
N11.1 Chronic obstructive pyelonephritis	0.305	0.695	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.702	0.298
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.297	0.703	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.707	0.293
L40-L45 Papulosquamous disorders	0.281	0.718	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.728	0.272
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.268	0.732	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.264	0.736	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.250	0.750	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.246	0.754	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.754	0.246
N10 Acute tubulo-interstitial nephritis	0.226	0.774	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.778	0.222
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.781	0.219
N14.4 Toxic nephropathy, not elsewhere classified	0.213	0.787	0.000
N14.3 Nephropathy induced by heavy metals	0.213	0.787	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.213	0.787	0.000
N14.0 Analgesic nephropathy	0.213	0.787	0.000
L42 Pityriasis rosea	0.209	0.791	0.000
L44 Other papulosquamous disorders	0.207	0.793	0.000
L41 Parapsoriasis	0.202	0.798	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.202	0.798	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.802	0.198
N15 Other renal tubulo-interstitial diseases	0.197	0.802	0.000
E00-E07 Disorders of thyroid gland	0.191	0.809	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.189	0.810	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.189	0.810	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.189	0.810	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.189	0.810	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.189	0.810	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.189	0.810	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.189	0.810	0.000
M06 Other rheumatoid arthritis	0.000	0.826	0.173
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.829	0.171
E83 Disorders of mineral metabolism	0.000	0.830	0.170
Chapter IV Endocrine, nutritional and metabolic diseases	0.170	0.830	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.831	0.169
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.833	0.167
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.835	0.165
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.165	0.835	0.000
E16 Other disorders of pancreatic internal secretion	0.162	0.838	0.000
E16.2 Hypoglycaemia, unspecified	0.161	0.839	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.842	0.157
E50-E64 Other nutritional deficiencies	0.157	0.843	0.000
E61 Deficiency of other nutrient elements	0.154	0.846	0.000
L44.0 Pityriasis rubra pilaris	0.153	0.847	0.000
E10-E14 Diabetes mellitus	0.152	0.848	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.850	0.150
E10 Insulin-dependent diabetes mellitus	0.149	0.851	0.000
L44.9 Papulosquamous disorder, unspecified	0.148	0.851	0.000
L44.8 Other specified papulosquamous disorders	0.148	0.851	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.148	0.851	0.000
L44.3 Lichen ruber moniliformis	0.148	0.851	0.000
L44.2 Lichen striatus	0.148	0.851	0.000
L44.1 Lichen nitidus	0.148	0.851	0.000
E61.1 Iron deficiency	0.148	0.852	0.000
L41.9 Parapsoriasis, unspecified	0.145	0.855	0.000
L41.8 Other parapsoriasis	0.145	0.855	0.000
L41.5 Retiform parapsoriasis	0.145	0.855	0.000
L41.4 Large plaque parapsoriasis	0.145	0.855	0.000
L41.3 Small plaque parapsoriasis	0.145	0.855	0.000
L41.2 Lymphomatoid papulosis	0.145	0.855	0.000
L41.1 Pityriasis lichenoides chronica	0.145	0.855	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.145	0.855	0.000
E07 Other disorders of thyroid	0.144	0.856	0.000
M05-M14 Inflammatory polyarthropathies	0.001	0.856	0.143
N15.8 Other specified renal tubulo-interstitial diseases	0.142	0.858	0.000
N15.0 Balkan nephropathy	0.142	0.858	0.000
E10.9 Without complications	0.138	0.862	0.000
E10.1 With ketoacidosis	0.138	0.862	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.137	0.863	0.000
E00 Congenital iodine-deficiency syndrome	0.137	0.863	0.000
E10.2 With renal complications	0.136	0.864	0.000
E61.2 Magnesium deficiency	0.135	0.865	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.133	0.867	0.000
E40-E46 Malnutrition	0.132	0.867	0.000
E20-E35 Disorders of other endocrine glands	0.132	0.868	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.872	0.128
M05.8 Other seropositive rheumatoid arthritis	0.000	0.872	0.127
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.873	0.127
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.125	0.875	0.000
M06.2 Rheumatoid bursitis	0.000	0.875	0.124
M06.1 Adult-onset Still's disease	0.000	0.875	0.124
E16.1 Other hypoglycaemia	0.124	0.876	0.000
E83.8 Other disorders of mineral metabolism	0.000	0.878	0.122
E83.2 Disorders of zinc metabolism	0.000	0.878	0.122
E83.0 Disorders of copper metabolism	0.000	0.878	0.122
E14 Unspecified diabetes mellitus	0.121	0.879	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.879	0.121
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.879	0.121
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.879	0.121
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.879	0.121
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.879	0.121
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.879	0.121
M05.2 Rheumatoid vasculitis	0.000	0.880	0.120
N15.1 Renal and perinephric abscess	0.119	0.880	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.881	0.119
E10.3 With ophthalmic complications	0.119	0.881	0.000
E15 Nondiabetic hypoglycaemic coma	0.119	0.881	0.000
M14 Arthropathies in other diseases classified elsewhere	0.001	0.883	0.116
E16.9 Disorder of pancreatic internal secretion, unspecified	0.117	0.883	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.117	0.883	0.000
E16.4 Abnormal secretion of gastrin	0.117	0.883	0.000
E16.3 Increased secretion of glucagon	0.117	0.883	0.000
E21.0 Primary hyperparathyroidism	0.116	0.884	0.000
E58 Dietary calcium deficiency	0.115	0.885	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.885	0.115
E51 Thiamine deficiency	0.115	0.885	0.000
E10.0 With coma	0.114	0.886	0.000
M05.1 Rheumatoid lung disease	0.000	0.886	0.114
M12 Other specific arthropathies	0.001	0.886	0.114
E56 Other vitamin deficiencies	0.114	0.886	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.114	0.886	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.887	0.113
M05.0 Felty's syndrome	0.000	0.887	0.113
E64 Sequelae of malnutrition and other nutritional deficiencies	0.112	0.887	0.000
E63 Other nutritional deficiencies	0.112	0.887	0.000
E50 Vitamin A deficiency	0.112	0.887	0.000
E60 Dietary zinc deficiency	0.112	0.887	0.000
E59 Dietary selenium deficiency	0.112	0.887	0.000
E52 Niacin deficiency [pellagra]	0.112	0.887	0.000
L43 Lichen planus	0.112	0.888	0.000
E07.8 Other specified disorders of thyroid	0.111	0.889	0.000
E61.9 Deficiency of nutrient element, unspecified	0.111	0.889	0.000
E61.8 Deficiency of other specified nutrient elements	0.111	0.889	0.000
E61.7 Deficiency of multiple nutrient elements	0.111	0.889	0.000
E61.6 Vanadium deficiency	0.111	0.889	0.000
E61.5 Molybdenum deficiency	0.111	0.889	0.000
E61.4 Chromium deficiency	0.111	0.889	0.000
E61.3 Manganese deficiency	0.111	0.889	0.000
E61.0 Copper deficiency	0.111	0.889	0.000
E55 Vitamin D deficiency	0.111	0.889	0.000
E20 Hypoparathyroidism	0.110	0.889	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.110	0.890	0.000
E12 Malnutrition-related diabetes mellitus	0.109	0.891	0.000
E21.3 Hyperparathyroidism, unspecified	0.108	0.892	0.000
E54 Ascorbic acid deficiency	0.108	0.892	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.893	0.107
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.894	0.106
E46 Unspecified protein-energy malnutrition	0.105	0.894	0.000
E14.5 With peripheral circulatory complications	0.105	0.895	0.000
E32 Diseases of thymus	0.105	0.895	0.000
E07.9 Disorder of thyroid, unspecified	0.104	0.896	0.000
E24 Cushing's syndrome	0.104	0.896	0.000
E07.1 Dyshormogenetic goitre	0.104	0.896	0.000
E07.0 Hypersecretion of calcitonin	0.104	0.896	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.001	0.896	0.103
E10.7 With multiple complications	0.103	0.897	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.897	0.103
M14.6 Neuropathic arthropathy	0.000	0.897	0.102
E14.2 Withrenal complications	0.102	0.898	0.000
E06 Thyroiditis	0.102	0.898	0.000
E25 Adrenogenital disorders	0.102	0.898	0.000
E14.3 With ophthalmic complications	0.100	0.900	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.900	0.100
E29 Testicular dysfunction	0.099	0.901	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.098	0.902	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.098	0.902	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.098	0.902	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.098	0.902	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.098	0.902	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.098	0.902	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.098	0.902	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.098	0.902	0.000
E31 Polyglandular dysfunction	0.097	0.903	0.000
E14.4 With neurological complications	0.097	0.903	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.905	0.095
E44 Protein-energy malnutrition of moderate and mild degree	0.095	0.905	0.000
E45 Retarded development following protein-energy malnutrition	0.095	0.905	0.000
E43 Unspecified severe protein-energy malnutrition	0.095	0.905	0.000
E42 Marasmic kwashiorkor	0.095	0.905	0.000
E41 Nutritional marasmus	0.095	0.905	0.000
E40 Kwashiorkor	0.095	0.905	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.095	0.905	0.000
E30 Disorders of puberty, not elsewhere classified	0.095	0.905	0.000
M08 Juvenile arthritis	0.001	0.906	0.093
E10.4 With neurological complications	0.094	0.906	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.907	0.093
E21.5 Disorder of parathyroid gland, unspecified	0.093	0.907	0.000
E20.9 Hypoparathyroidism, unspecified	0.092	0.908	0.000
E10.6 With other specified complications	0.092	0.908	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.908	0.092
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.908	0.092
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.908	0.092
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.908	0.092
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.908	0.092
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.908	0.092
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.908	0.092
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.908	0.092
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.908	0.092
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.908	0.091
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.908	0.091
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.908	0.091
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.908	0.091
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.908	0.091
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.908	0.091
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.908	0.091
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.908	0.091
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.908	0.091
M12.3 Palindromic rheumatism	0.001	0.909	0.090
E13 Other specified diabetes mellitus	0.090	0.909	0.000
E10.8 With unspecified complications	0.090	0.910	0.000
E21.4 Other specified disorders of parathyroid gland	0.090	0.910	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.910	0.089
M06.18 Adult-onset Still's disease (Other)	0.000	0.910	0.089
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.910	0.089
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.910	0.089
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.910	0.089
M06.14 Adult-onset Still's disease (Hand)	0.000	0.910	0.089
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.910	0.089
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.910	0.089
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.910	0.089
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.910	0.089
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.910	0.089
M06.28 Rheumatoid bursitis (Other)	0.000	0.910	0.089
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.910	0.089
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.910	0.089
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.910	0.089
M06.24 Rheumatoid bursitis (Hand)	0.000	0.910	0.089
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.910	0.089
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.910	0.089
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.910	0.089
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.910	0.089
M12.2 Villonodular synovitis (pigmented)	0.001	0.912	0.088
M06.3 Rheumatoid nodule	0.000	0.912	0.088
E14.7 With multiple complications	0.087	0.913	0.000
E14.0 With coma	0.087	0.913	0.000
E21.2 Other hyperparathyroidism	0.087	0.913	0.000
M05.28 Rheumatoid vasculitis (Other)	0.000	0.913	0.086
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.913	0.086
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.913	0.086
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.913	0.086
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.913	0.086
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.913	0.086
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.913	0.086
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.913	0.086
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.913	0.086
E32.8 Other diseases of thymus	0.086	0.914	0.000
E14.8 With unspecified complications	0.085	0.915	0.000
E51.2 Wernicke's encephalopathy	0.084	0.915	0.000
E20.8 Other hypoparathyroidism	0.084	0.915	0.000
E24.2 Drug-induced Cushing's syndrome	0.084	0.916	0.000
E23 Hypofunction and other disorders of pituitary gland	0.084	0.916	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.001	0.916	0.084
M14.4 Arthropathy in amyloidosis	0.001	0.916	0.084
M14.3 Lipoid dermatoarthritis	0.001	0.916	0.084
M14.1 Crystal arthropathy in other metabolic disorders	0.001	0.916	0.084
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.001	0.916	0.084
M14.8 Arthropathies in other specified diseases classified elsewhere	0.001	0.916	0.083
E24.0 Pituitary-dependent Cushing's disease	0.084	0.916	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.916	0.083
E56.1 Deficiency of vitamin K	0.083	0.917	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.917	0.083
E34 Other endocrine disorders	0.083	0.917	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.917	0.082
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.917	0.082
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.917	0.082
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.917	0.082
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.917	0.082
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.917	0.082
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.917	0.082
E51.9 Thiamine deficiency, unspecified	0.082	0.917	0.000
E51.8 Other manifestations of thiamine deficiency	0.082	0.917	0.000
E51.1 Beriberi	0.082	0.917	0.000
M05.18 Rheumatoid lung disease (Other)	0.000	0.918	0.082
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.918	0.082
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.918	0.082
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.918	0.082
M05.14 Rheumatoid lung disease (Hand)	0.000	0.918	0.082
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.918	0.082
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.918	0.082
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.918	0.082
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.918	0.082
M12.5 Traumatic arthropathy	0.001	0.918	0.081
M12.4 Intermittent hydrarthrosis	0.001	0.918	0.081
M12.1 Kaschin-Beck disease	0.001	0.918	0.081
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.001	0.918	0.081
E56.9 Vitamin deficiency, unspecified	0.082	0.918	0.000
E56.8 Deficiency of other vitamins	0.082	0.918	0.000
E56.0 Deficiency of vitamin E	0.082	0.918	0.000
M05.09 Felty's syndrome (Site unspecified)	0.000	0.918	0.081
M05.08 Felty's syndrome (Other)	0.000	0.918	0.081
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.918	0.081
M05.06 Felty's syndrome (Lower leg)	0.000	0.918	0.081
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.918	0.081
M05.04 Felty's syndrome (Hand)	0.000	0.918	0.081
M05.03 Felty's syndrome (Forearm)	0.000	0.918	0.081
M05.02 Felty's syndrome (Upper arm)	0.000	0.918	0.081
M05.01 Felty's syndrome (Shoulder region)	0.000	0.918	0.081
M05.00 Felty's syndrome (Multiple sites)	0.000	0.918	0.081
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.918	0.081
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.918	0.081
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.918	0.081
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.918	0.081
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.918	0.081
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.918	0.081
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.918	0.081
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.918	0.081
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.918	0.081
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.918	0.081
E14.1 With ketoacidosis	0.081	0.919	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.919	0.081
E50.9 Vitamin A deficiency, unspecified	0.081	0.919	0.000
E50.8 Other manifestations of vitamin A deficiency	0.081	0.919	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.081	0.919	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.081	0.919	0.000
E50.5 Vitamin A deficiency with night blindness	0.081	0.919	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.081	0.919	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.081	0.919	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.081	0.919	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.081	0.919	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.081	0.919	0.000
E63.9 Nutritional deficiency, unspecified	0.081	0.919	0.000
E63.8 Other specified nutritional deficiencies	0.081	0.919	0.000
E63.1 Imbalance of constituents of food intake	0.081	0.919	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.081	0.919	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.081	0.919	0.000
E64.8 Sequelae of other nutritional deficiencies	0.081	0.919	0.000
E64.3 Sequelae of rickets	0.081	0.919	0.000
E64.2 Sequelae of vitamin C deficiency	0.081	0.919	0.000
E64.1 Sequelae of vitamin A deficiency	0.081	0.919	0.000
E64.0 Sequelae of protein-energy malnutrition	0.081	0.919	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.081	0.919	0.000
L43.3 Subacute (active) lichen planus	0.080	0.919	0.000
L43.2 Lichenoid drug reaction	0.080	0.919	0.000
L43.1 Bullous lichen planus	0.080	0.919	0.000
L43.0 Hypertrophic lichen planus	0.080	0.919	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.920	0.080
E55.0 Rickets, active	0.079	0.920	0.000
E20.1 Pseudohypoparathyroidism	0.079	0.921	0.000
E20.0 Idiopathic hypoparathyroidism	0.079	0.921	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.079	0.921	0.000
E06.9 Thyroiditis, unspecified	0.079	0.921	0.000
E12.9 Without complications	0.078	0.922	0.000
E12.8 With unspecified complications	0.078	0.922	0.000
E12.7 With multiple complications	0.078	0.922	0.000
E12.6 With other specified complications	0.078	0.922	0.000
E12.5 With peripheral circulatory complications	0.078	0.922	0.000
E12.4 With neurological complications	0.078	0.922	0.000
E12.3 With ophthalmic complications	0.078	0.922	0.000
E12.2 With renal complications	0.078	0.922	0.000
E12.1 With ketoacidosis	0.078	0.922	0.000
E12.0 With coma	0.078	0.922	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.001	0.922	0.078
E55.9 Vitamin D deficiency, unspecified	0.078	0.922	0.000
E26 Hyperaldosteronism	0.077	0.923	0.000
E29.9 Testicular dysfunction, unspecified	0.077	0.923	0.000
E32.9 Disease of thymus, unspecified	0.075	0.925	0.000
E32.1 Abscess of thymus	0.075	0.925	0.000
E32.0 Persistent hyperplasia of thymus	0.075	0.925	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.075	0.925	0.000
E24.3 Ectopic ACTH syndrome	0.075	0.925	0.000
E24.1 Nelson's syndrome	0.075	0.925	0.000
E24.8 Other Cushing's syndrome	0.075	0.925	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.001	0.925	0.074
M09.2 Juvenile arthritis in ulcerative colitis	0.001	0.925	0.074
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.001	0.925	0.074
M09.0 Juvenile arthritis in psoriasis	0.001	0.925	0.074
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.926	0.073
E06.1 Subacute thyroiditis	0.073	0.926	0.000
E06.4 Drug-induced thyroiditis	0.073	0.927	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.073	0.927	0.000
E06.0 Acute thyroiditis	0.073	0.927	0.000
E25.9 Adrenogenital disorder, unspecified	0.073	0.927	0.000
E25.8 Other adrenogenital disorders	0.073	0.927	0.000
M14.2 Diabetic arthropathy	0.001	0.927	0.072
E14.6 With other specified complications	0.073	0.927	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.927	0.073
E31.0 Autoimmune polyglandular failure	0.072	0.927	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.928	0.072
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.928	0.072
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.928	0.072
E06.5 Other chronic thyroiditis	0.071	0.928	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.000	0.928	0.071
E29.8 Other testicular dysfunction	0.071	0.929	0.000
E29.0 Testicular hyperfunction	0.071	0.929	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.000	0.929	0.071
E29.1 Testicular hypofunction	0.071	0.929	0.000
K90-K93 Other diseases of the digestive system	0.070	0.930	0.000
L43.8 Other lichen planus	0.070	0.930	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.930	0.070
E31.9 Polyglandular dysfunction, unspecified	0.070	0.930	0.000
E31.8 Other polyglandular dysfunction	0.070	0.930	0.000
E31.1 Polyglandular hyperfunction	0.070	0.930	0.000
E03 Other hypothyroidism	0.070	0.930	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.931	0.069
I69.3 Sequelae of cerebral infarction	0.000	0.931	0.069
E13.3 With ophthalmic complications	0.069	0.931	0.000
E44.1 Mild protein-energy malnutrition	0.068	0.931	0.000
E44.0 Moderate protein-energy malnutrition	0.068	0.931	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.932	0.068
E30.9 Disorder of puberty, unspecified	0.068	0.932	0.000
E30.8 Other disorders of puberty	0.068	0.932	0.000
E30.1 Precocious puberty	0.068	0.932	0.000
E30.0 Delayed puberty	0.068	0.932	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.068	0.932	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.068	0.932	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.068	0.932	0.000
M08.8 Other juvenile arthritis	0.001	0.932	0.067
M08.4 Pauciarticular juvenile arthritis	0.001	0.932	0.067
M08.3 Juvenile polyarthritis (seronegative)	0.001	0.932	0.067
M08.2 Juvenile arthritis with systemic onset	0.001	0.932	0.067
M08.1 Juvenile ankylosing spondylitis	0.001	0.932	0.067
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.932	0.067
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.932	0.067
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.933	0.067
M06.34 Rheumatoid nodule (Hand)	0.000	0.934	0.066
M11 Other crystal arthropathies	0.002	0.934	0.064
M07 Psoriatic and enteropathic arthropathies	0.013	0.934	0.053
E27 Other disorders of adrenal gland	0.066	0.934	0.000
E23.7 Disorder of pituitary gland, unspecified	0.065	0.934	0.000
M12.38 Palindromic rheumatism (Other)	0.001	0.935	0.065
M12.37 Palindromic rheumatism (Ankle and foot)	0.001	0.935	0.065
M12.36 Palindromic rheumatism (Lower leg)	0.001	0.935	0.065
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.001	0.935	0.065
M12.34 Palindromic rheumatism (Hand)	0.001	0.935	0.065
M12.33 Palindromic rheumatism (Forearm)	0.001	0.935	0.065
M12.32 Palindromic rheumatism (Upper arm)	0.001	0.935	0.065
M12.31 Palindromic rheumatism (Shoulder region)	0.001	0.935	0.065
E13.8 With unspecified complications	0.065	0.935	0.000
E13.7 With multiple complications	0.065	0.935	0.000
E13.6 With other specified complications	0.065	0.935	0.000
E13.5 With peripheral circulatory complications	0.065	0.935	0.000
E13.4 With neurological complications	0.065	0.935	0.000
E13.2 With renal complications	0.065	0.935	0.000
E13.1 With ketoacidosis	0.065	0.935	0.000
E13.0 With coma	0.065	0.935	0.000
E23.2 Diabetes insipidus	0.064	0.936	0.000
E34.3 Short stature, not elsewhere classified	0.064	0.936	0.000
M08.9 Juvenile arthritis, unspecified	0.001	0.936	0.063
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.001	0.936	0.063
M12.28 Villonodular synovitis (pigmented) (Other)	0.001	0.936	0.063
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.001	0.936	0.063
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.001	0.936	0.063
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.001	0.936	0.063
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.001	0.936	0.063
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.001	0.936	0.063
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.001	0.936	0.063
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.936	0.063
M06.38 Rheumatoid nodule (Other)	0.000	0.936	0.063
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.936	0.063
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.936	0.063
M06.33 Rheumatoid nodule (Forearm)	0.000	0.936	0.063
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.936	0.063
M08.0 Juvenile rheumatoid arthritis	0.001	0.937	0.062
E24.9 Cushing's syndrome, unspecified	0.062	0.938	0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.001	0.939	0.061
E34.9 Endocrine disorder, unspecified	0.061	0.939	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations