TreeWAS – Variant ID: rs3132454

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
R31 Unspecified haematuria	0.994	0.006	0.000
E03 Other hypothyroidism	0.000	0.008	0.992
E00-E07 Disorders of thyroid gland	0.000	0.018	0.982
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.019	0.981
E05.9 Thyrotoxicosis, unspecified	0.000	0.031	0.969
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.069	0.931
E03.8 Other specified hypothyroidism	0.000	0.150	0.850
E04 Other non-toxic goitre	0.000	0.221	0.779
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.229	0.771
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.240	0.760
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.242	0.758
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.261	0.739
E05.8 Other thyrotoxicosis	0.000	0.281	0.719
E03.5 Myxoedema coma	0.000	0.289	0.711
E03.4 Atrophy of thyroid (acquired)	0.000	0.289	0.711
E03.3 Postinfectious hypothyroidism	0.000	0.289	0.711
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.295	0.704
E00 Congenital iodine-deficiency syndrome	0.000	0.295	0.704
E05.5 Thyroid crisis or storm	0.000	0.297	0.703
E05.4 Thyrotoxicosis factitia	0.000	0.297	0.703
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.297	0.703
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.297	0.703
E04.9 Non-toxic goitre, unspecified	0.000	0.315	0.685
E04.0 Non-toxic diffuse goitre	0.000	0.317	0.683
E07 Other disorders of thyroid	0.000	0.358	0.641
E06 Thyroiditis	0.001	0.384	0.615
E03.1 Congenital hypothyroidism without goitre	0.000	0.429	0.571
E06.3 Autoimmune thyroiditis	0.000	0.431	0.569
E07.8 Other specified disorders of thyroid	0.000	0.441	0.559
E04.8 Other specified non-toxic goitre	0.000	0.441	0.559
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.495	0.505
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.495	0.505
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.495	0.505
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.495	0.505
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.495	0.505
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.495	0.505
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.495	0.505
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.495	0.505
E07.1 Dyshormogenetic goitre	0.000	0.540	0.460
E07.0 Hypersecretion of calcitonin	0.000	0.540	0.460
E04.2 Non-toxic multinodular goitre	0.000	0.549	0.451
E06.4 Drug-induced thyroiditis	0.001	0.558	0.441
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.558	0.441
E06.0 Acute thyroiditis	0.001	0.558	0.441
E06.5 Other chronic thyroiditis	0.001	0.629	0.371
K90 Intestinal malabsorption	0.000	0.651	0.349
E06.1 Subacute thyroiditis	0.001	0.683	0.316
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.708	0.292
E04.1 Non-toxic single thyroid nodule	0.000	0.746	0.254
K90.3 Pancreatic steatorrhoea	0.000	0.750	0.250
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.750	0.250
K90.1 Tropical sprue	0.000	0.750	0.250
K90.8 Other intestinal malabsorption	0.000	0.767	0.232
E06.9 Thyroiditis, unspecified	0.002	0.788	0.210
E27.1 Primary adrenocortical insufficiency	0.000	0.832	0.168
K90.9 Intestinal malabsorption, unspecified	0.000	0.861	0.139
D18.0 Haemangioma, any site	0.107	0.893	0.000
E07.9 Disorder of thyroid, unspecified	0.001	0.895	0.105
E27 Other disorders of adrenal gland	0.000	0.903	0.097
E27.2 Addisonian crisis	0.000	0.911	0.089
E27.5 Adrenomedullary hyperfunction	0.000	0.930	0.070
E27.0 Other adrenocortical overactivity	0.000	0.930	0.070
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.930	0.070
E20-E35 Disorders of other endocrine glands	0.000	0.933	0.067
D18 Haemangioma and lymphangioma, any site	0.065	0.935	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.939	0.061
E27.8 Other specified disorders of adrenal gland	0.000	0.940	0.060
E40-E46 Malnutrition	0.000	0.942	0.058
D18.1 Lymphangioma, any site	0.056	0.944	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.945	0.055
E28 Ovarian dysfunction	0.000	0.946	0.054
E24 Cushing's syndrome	0.000	0.947	0.053
E46 Unspecified protein-energy malnutrition	0.000	0.950	0.050
E22 Hyperfunction of pituitary gland	0.000	0.951	0.049
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.952	0.048
E32 Diseases of thymus	0.000	0.952	0.048
E31 Polyglandular dysfunction	0.000	0.952	0.048
E30 Disorders of puberty, not elsewhere classified	0.000	0.952	0.048
E27.3 Drug-induced adrenocortical insufficiency	0.001	0.956	0.044
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.957	0.043
E24.0 Pituitary-dependent Cushing's disease	0.000	0.957	0.043
E28.3 Primary ovarian failure	0.000	0.957	0.043
E28.2 Polycystic ovarian syndrome	0.000	0.958	0.042
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.958	0.042
E45 Retarded development following protein-energy malnutrition	0.000	0.958	0.042
E43 Unspecified severe protein-energy malnutrition	0.000	0.958	0.042
E42 Marasmic kwashiorkor	0.000	0.958	0.042
E41 Nutritional marasmus	0.000	0.958	0.042
E40 Kwashiorkor	0.000	0.958	0.042
E25 Adrenogenital disorders	0.000	0.958	0.041
E20 Hypoparathyroidism	0.000	0.959	0.041
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.960	0.040
E24.9 Cushing's syndrome, unspecified	0.000	0.960	0.040
E28.9 Ovarian dysfunction, unspecified	0.000	0.961	0.039
E28.8 Other ovarian dysfunction	0.000	0.961	0.039
E28.1 Androgen excess	0.000	0.961	0.039
E28.0 Oestrogen excess	0.000	0.961	0.039
E34 Other endocrine disorders	0.000	0.961	0.039
E22.0 Acromegaly and pituitary gigantism	0.000	0.962	0.038
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.962	0.038
E24.3 Ectopic ACTH syndrome	0.000	0.962	0.038
E24.1 Nelson's syndrome	0.000	0.962	0.038
E24.2 Drug-induced Cushing's syndrome	0.000	0.963	0.037
E26 Hyperaldosteronism	0.000	0.963	0.037
E24.8 Other Cushing's syndrome	0.000	0.964	0.036
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.965	0.035
E22.8 Other hyperfunction of pituitary gland	0.000	0.965	0.035
E30.9 Disorder of puberty, unspecified	0.000	0.965	0.035
E30.8 Other disorders of puberty	0.000	0.965	0.035
E30.1 Precocious puberty	0.000	0.965	0.035
E30.0 Delayed puberty	0.000	0.965	0.035
E31.9 Polyglandular dysfunction, unspecified	0.000	0.965	0.035
E31.8 Other polyglandular dysfunction	0.000	0.965	0.035
E31.1 Polyglandular hyperfunction	0.000	0.965	0.035
E31.0 Autoimmune polyglandular failure	0.000	0.965	0.035
E32.9 Disease of thymus, unspecified	0.000	0.965	0.035
E32.8 Other diseases of thymus	0.000	0.965	0.035
E32.1 Abscess of thymus	0.000	0.965	0.035
E32.0 Persistent hyperplasia of thymus	0.000	0.965	0.035
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.965	0.035
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.965	0.035
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.965	0.035
E23 Hypofunction and other disorders of pituitary gland	0.000	0.965	0.035
E29 Testicular dysfunction	0.000	0.968	0.031
E15 Nondiabetic hypoglycaemic coma	0.000	0.969	0.031
E44.1 Mild protein-energy malnutrition	0.000	0.970	0.030
E44.0 Moderate protein-energy malnutrition	0.000	0.970	0.030
E25.9 Adrenogenital disorder, unspecified	0.000	0.970	0.030
E25.8 Other adrenogenital disorders	0.000	0.970	0.030
E20.8 Other hypoparathyroidism	0.000	0.970	0.030
E20.1 Pseudohypoparathyroidism	0.000	0.970	0.030
E20.0 Idiopathic hypoparathyroidism	0.000	0.970	0.030
E34.9 Endocrine disorder, unspecified	0.000	0.971	0.029
K90-K93 Other diseases of the digestive system	0.000	0.971	0.029
E34.5 Androgen resistance syndrome	0.000	0.972	0.028
E34.4 Constitutional tall stature	0.000	0.972	0.028
E34.3 Short stature, not elsewhere classified	0.000	0.972	0.028
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.972	0.028
E34.1 Other hypersecretion of intestinal hormones	0.000	0.972	0.028
E50-E64 Other nutritional deficiencies	0.000	0.972	0.028
M20.5 Other deformities of toe(s) (acquired)	0.028	0.972	0.000
E23.6 Other disorders of pituitary gland	0.000	0.973	0.027
E26.8 Other hyperaldosteronism	0.000	0.973	0.027
E26.1 Secondary hyperaldosteronism	0.000	0.973	0.027
D69.6 Thrombocytopenia, unspecified	0.000	0.973	0.027
T78.1 Other adverse food reactions, not elsewhere classified	0.026	0.974	0.000
R17 Unspecified jaundice	0.000	0.975	0.025
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.975	0.025
E23.1 Drug-induced hypopituitarism	0.000	0.975	0.025
E26.9 Hyperaldosteronism, unspecified	0.000	0.975	0.024
E16 Other disorders of pancreatic internal secretion	0.000	0.975	0.025
E34.8 Other specified endocrine disorders	0.000	0.976	0.024
E23.2 Diabetes insipidus	0.000	0.976	0.024
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.976	0.023
E34.0 Carcinoid syndrome	0.000	0.977	0.023
R30-R39 Symptoms and signs involving the urinary system	0.023	0.977	0.000
E29.8 Other testicular dysfunction	0.000	0.977	0.023
E29.0 Testicular hyperfunction	0.000	0.977	0.023
E22.1 Hyperprolactinaemia	0.000	0.977	0.023
E20.9 Hypoparathyroidism, unspecified	0.000	0.977	0.023
E23.7 Disorder of pituitary gland, unspecified	0.000	0.977	0.023
E29.9 Testicular dysfunction, unspecified	0.000	0.978	0.022
G35 Multiple sclerosis	0.000	0.979	0.021
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.979	0.021
R33 Retention of urine	0.021	0.979	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.980	0.020
E63 Other nutritional deficiencies	0.000	0.980	0.020
E50 Vitamin A deficiency	0.000	0.980	0.020
E60 Dietary zinc deficiency	0.000	0.980	0.020
E59 Dietary selenium deficiency	0.000	0.980	0.020
E58 Dietary calcium deficiency	0.000	0.980	0.020
E52 Niacin deficiency [pellagra]	0.000	0.980	0.020
E53 Deficiency of other B group vitamins	0.000	0.980	0.020
E54 Ascorbic acid deficiency	0.000	0.980	0.020
E51 Thiamine deficiency	0.000	0.980	0.020
E26.0 Primary hyperaldosteronism	0.000	0.980	0.019
Q23.1 Congenital insufficiency of aortic valve	0.020	0.980	0.000
E56 Other vitamin deficiencies	0.000	0.981	0.019
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.981	0.019
T78 Adverse effects, not elsewhere classified	0.018	0.982	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.982	0.018
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.982	0.018
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.982	0.018
E16.4 Abnormal secretion of gastrin	0.000	0.982	0.018
E16.3 Increased secretion of glucagon	0.000	0.982	0.018
R36 Urethral discharge	0.018	0.982	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.982	0.018
T78.3 Angioneurotic oedema	0.017	0.983	0.000
E55 Vitamin D deficiency	0.000	0.983	0.016
E16.1 Other hypoglycaemia	0.000	0.985	0.015
Q23 Congenital malformations of aortic and mitral valves	0.015	0.985	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.985	0.015
K93.1 Megacolon in Chagas' disease	0.000	0.985	0.015
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.985	0.015
T78.9 Adverse effect, unspecified	0.015	0.985	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.985	0.015
E50.8 Other manifestations of vitamin A deficiency	0.000	0.985	0.015
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.985	0.015
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.985	0.015
E50.5 Vitamin A deficiency with night blindness	0.000	0.985	0.015
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.985	0.015
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.985	0.015
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.985	0.015
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.985	0.015
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.985	0.015
E63.9 Nutritional deficiency, unspecified	0.000	0.985	0.015
E63.8 Other specified nutritional deficiencies	0.000	0.985	0.015
E63.1 Imbalance of constituents of food intake	0.000	0.985	0.015
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.985	0.015
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.985	0.015
E64.8 Sequelae of other nutritional deficiencies	0.000	0.985	0.015
E64.3 Sequelae of rickets	0.000	0.985	0.015
E64.2 Sequelae of vitamin C deficiency	0.000	0.985	0.015
E64.1 Sequelae of vitamin A deficiency	0.000	0.985	0.015
E64.0 Sequelae of protein-energy malnutrition	0.000	0.985	0.015
E53.1 Pyridoxine deficiency	0.000	0.985	0.015
E53.0 Riboflavin deficiency	0.000	0.985	0.015
T78.8 Other adverse effects, not elsewhere classified	0.014	0.985	0.000
E51.9 Thiamine deficiency, unspecified	0.000	0.985	0.014
E51.8 Other manifestations of thiamine deficiency	0.000	0.985	0.014
E51.1 Beriberi	0.000	0.985	0.014
E56.9 Vitamin deficiency, unspecified	0.000	0.986	0.014
E56.8 Deficiency of other vitamins	0.000	0.986	0.014
E56.0 Deficiency of vitamin E	0.000	0.986	0.014
T78.0 Anaphylactic shock due to adverse food reaction	0.014	0.986	0.000
E51.2 Wernicke's encephalopathy	0.000	0.986	0.014
E67 Other hyperalimentation	0.000	0.987	0.013
E68 Sequelae of hyperalimentation	0.000	0.987	0.013
E56.1 Deficiency of vitamin K	0.000	0.987	0.013
R34 Anuria and oliguria	0.013	0.987	0.000
E23.0 Hypopituitarism	0.000	0.987	0.013
E16.2 Hypoglycaemia, unspecified	0.000	0.987	0.013
Q23.0 Congenital stenosis of aortic valve	0.012	0.988	0.000
E55.0 Rickets, active	0.000	0.988	0.012
E61 Deficiency of other nutrient elements	0.000	0.988	0.012
S06.20 Diffuse brain injury (without open intracranial wound)	0.012	0.988	0.000
T66-T78 Other and unspecified effects of external causes	0.012	0.988	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.011	0.989	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.011	0.989	0.000
Q23.4 Hypoplastic left heart syndrome	0.011	0.989	0.000
Q23.2 Congenital mitral stenosis	0.011	0.989	0.000
Q25 Congenital malformations of great arteries	0.011	0.989	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.011	0.989	0.000
Q23.3 Congenital mitral insufficiency	0.011	0.989	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.989	0.011
Q20-Q28 Congenital malformations of the circulatory system	0.011	0.989	0.000
R30 Pain associated with micturition	0.011	0.989	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.011	0.989	0.000
J31.0 Chronic rhinitis	0.010	0.990	0.000
T70 Effects of air pressure and water pressure	0.010	0.990	0.000
T75 Effects of other external causes	0.010	0.990	0.000
Q25.4 Other congenital malformations of aorta	0.010	0.990	0.000
E67.8 Other specified hyperalimentation	0.000	0.990	0.009
E67.3 Hypervitaminosis D	0.000	0.990	0.009
E67.2 Megavitamin-B6 syndrome	0.000	0.990	0.009
E67.1 Hypercarotenaemia	0.000	0.990	0.009
E67.0 Hypervitaminosis A	0.000	0.990	0.009
Q25.1 Coarctation of aorta	0.010	0.990	0.000
T71 Asphyxiation	0.009	0.990	0.000
S06.2 Diffuse brain injury	0.009	0.990	0.000
Q24 Other congenital malformations of heart	0.009	0.990	0.000
Q21 Congenital malformations of cardiac septa	0.009	0.991	0.000
Q25.6 Stenosis of pulmonary artery	0.009	0.991	0.000
D69.4 Other primary thrombocytopenia	0.000	0.991	0.009
D69.2 Other nonthrombocytopenic purpura	0.000	0.991	0.009
Q25.7 Other congenital malformations of pulmonary artery	0.009	0.991	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.991	0.009
T70.3 Caisson disease [decompression sickness]	0.009	0.991	0.000
S06.5 Traumatic subdural haemorrhage	0.009	0.991	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.991	0.008
E61.8 Deficiency of other specified nutrient elements	0.000	0.991	0.008
E61.7 Deficiency of multiple nutrient elements	0.000	0.991	0.008
E61.6 Vanadium deficiency	0.000	0.991	0.008
E61.5 Molybdenum deficiency	0.000	0.991	0.008
E61.4 Chromium deficiency	0.000	0.991	0.008
E61.3 Manganese deficiency	0.000	0.991	0.008
E61.0 Copper deficiency	0.000	0.991	0.008
T78.2 Anaphylactic shock, unspecified	0.009	0.991	0.000
E29.1 Testicular hypofunction	0.001	0.991	0.008
T74 Maltreatment syndromes	0.008	0.991	0.000
T73 Effects of other deprivation	0.008	0.991	0.000
T69 Other effects of reduced temperature	0.008	0.991	0.000
T67 Effects of heat and light	0.008	0.991	0.000
T75.4 Effects of electric current	0.008	0.991	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.008	0.991	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.992	0.008
Q25.9 Congenital malformation of great arteries, unspecified	0.008	0.992	0.000
Q25.8 Other congenital malformations of great arteries	0.008	0.992	0.000
Q25.5 Atresia of pulmonary artery	0.008	0.992	0.000
Q25.3 Stenosis of aorta	0.008	0.992	0.000
Q25.2 Atresia of aorta	0.008	0.992	0.000
Q26 Congenital malformations of great veins	0.008	0.992	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.008	0.992	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.992	0.008
T75.1 Drowning and nonfatal submersion	0.008	0.992	0.000
D69.0 Allergic purpura	0.000	0.992	0.008
D69.5 Secondary thrombocytopenia	0.000	0.992	0.008
E55.9 Vitamin D deficiency, unspecified	0.000	0.992	0.008
Q25.0 Patent ductus arteriosus	0.008	0.992	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.992	0.008
S06 Intracranial injury	0.008	0.992	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.992	0.008
Q21.1 Atrial septal defect	0.008	0.992	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.992	0.008
T78.4 Allergy, unspecified	0.008	0.992	0.000
Q24.5 Malformation of coronary vessels	0.008	0.992	0.000
R30.9 Painful micturition, unspecified	0.008	0.992	0.000
D69.1 Qualitative platelet defects	0.000	0.992	0.008
T70.9 Effect of air pressure and water pressure, unspecified	0.007	0.992	0.000
T70.8 Other effects of air pressure and water pressure	0.007	0.992	0.000
T70.4 Effects of high-pressure fluids	0.007	0.992	0.000
T70.2 Other and unspecified effects of high altitude	0.007	0.992	0.000
T70.1 Sinus barotrauma	0.007	0.992	0.000
T70.0 Otitic barotrauma	0.007	0.992	0.000
T75.8 Other specified effects of external causes	0.007	0.992	0.000
T75.3 Motion sickness	0.007	0.992	0.000
T75.2 Effects of vibration	0.007	0.992	0.000
T75.0 Effects of lightning	0.007	0.992	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.007	0.992	0.000
T66 Unspecified effects of radiation	0.007	0.992	0.000
E61.2 Magnesium deficiency	0.000	0.993	0.007
Q21.3 Tetralogy of Fallot	0.007	0.993	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.993	0.007
Q24.8 Other specified congenital malformations of heart	0.007	0.993	0.000
Q21.0 Ventricular septal defect	0.007	0.993	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.007	0.993	0.000
Q24.6 Congenital heart block	0.007	0.993	0.000
Q24.4 Congenital subaortic stenosis	0.007	0.993	0.000
Q24.3 Pulmonary infundibular stenosis	0.007	0.993	0.000
Q24.2 Cor triatriatum	0.007	0.993	0.000
Q24.1 Levocardia	0.007	0.993	0.000
Q24.0 Dextrocardia	0.007	0.993	0.000
Q21.8 Other congenital malformations of cardiac septa	0.007	0.993	0.000
Q21.4 Aortopulmonary septal defect	0.007	0.993	0.000
Q21.2 Atrioventricular septal defect	0.007	0.993	0.000
R30.1 Vesical tenesmus	0.007	0.993	0.000
Q22.1 Congenital pulmonary valve stenosis	0.007	0.993	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.007	0.993	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.007	0.993	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.007	0.993	0.000
K91.1 Postgastric surgery syndromes	0.000	0.993	0.006
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.993	0.006
M88.9 Paget's disease of bone, unspecified	0.007	0.993	0.000
T68 Hypothermia	0.006	0.993	0.000
E65 Localised adiposity	0.001	0.993	0.006
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.993	0.006
K91.5 Postcholecystectomy syndrome	0.000	0.993	0.006
G99.2 Myelopathy in diseases classified elsewhere	0.007	0.993	0.000
T67.9 Effects of heat and light, unspecified	0.006	0.994	0.000
T67.8 Other effects of heat and light	0.006	0.994	0.000
T67.7 Heat oedema	0.006	0.994	0.000
T67.6 Heat fatigue, transient	0.006	0.994	0.000
T67.5 Heat exhaustion, unspecified	0.006	0.994	0.000
T67.4 Heat exhaustion due to salt depletion	0.006	0.994	0.000
T67.3 Heat exhaustion, anhydrotic	0.006	0.994	0.000
T67.2 Heat cramp	0.006	0.994	0.000
T67.1 Heat syncope	0.006	0.994	0.000
T67.0 Heatstroke and sunstroke	0.006	0.994	0.000
T69.9 Effect of reduced temperature, unspecified	0.006	0.994	0.000
T69.8 Other specified effects of reduced temperature	0.006	0.994	0.000
T69.1 Chilblains	0.006	0.994	0.000
T69.0 Immersion hand and foot	0.006	0.994	0.000
T73.9 Effect of deprivation, unspecified	0.006	0.994	0.000
T73.8 Other effects of deprivation	0.006	0.994	0.000
T73.3 Exhaustion due to excessive exertion	0.006	0.994	0.000
T73.2 Exhaustion due to exposure	0.006	0.994	0.000
T73.1 Effects of thirst	0.006	0.994	0.000
T73.0 Effects of hunger	0.006	0.994	0.000
T74.9 Maltreatment syndrome, unspecified	0.006	0.994	0.000
T74.8 Other maltreatment syndromes	0.006	0.994	0.000
T74.3 Psychological abuse	0.006	0.994	0.000
T74.2 Sexual abuse	0.006	0.994	0.000
T74.1 Physical abuse	0.006	0.994	0.000
T74.0 Neglect or abandonment	0.006	0.994	0.000
S06.0 Concussion	0.006	0.994	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.006	0.994	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.006	0.994	0.000
Q22.6 Hypoplastic right heart syndrome	0.006	0.994	0.000
Q22.4 Congenital tricuspid stenosis	0.006	0.994	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.006	0.994	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.006	0.994	0.000
Q22.0 Pulmonary valve atresia	0.006	0.994	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.006	0.994	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.006	0.994	0.000
Q20.6 Isomerism of atrial appendages	0.006	0.994	0.000
Q20.5 Discordant atrioventricular connexion	0.006	0.994	0.000
Q20.4 Double inlet ventricle	0.006	0.994	0.000
Q20.3 Discordant ventriculoarterial connexion	0.006	0.994	0.000
Q20.2 Double outlet left ventricle	0.006	0.994	0.000
Q20.1 Double outlet right ventricle	0.006	0.994	0.000
Q20.0 Common arterial trunk	0.006	0.994	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.006	0.994	0.000
Q26.8 Other congenital malformations of great veins	0.006	0.994	0.000
Q26.6 Portal vein-hepatic artery fistula	0.006	0.994	0.000
Q26.5 Anomalous portal venous connexion	0.006	0.994	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.006	0.994	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.006	0.994	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.006	0.994	0.000
Q26.1 Persistent left superior vena cava	0.006	0.994	0.000
Q26.0 Congenital stenosis of vena cava	0.006	0.994	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.006	0.994	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.994	0.006
S06.1 Traumatic cerebral oedema	0.006	0.994	0.000
S06.7 Intracranial injury with prolonged coma	0.006	0.994	0.000
S06.4 Epidural haemorrhage	0.006	0.994	0.000
Q27 Other congenital malformations of peripheral vascular system	0.006	0.994	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.006	0.994	0.000
Q22.5 Ebstein's anomaly	0.006	0.994	0.000
F06.7 Mild cognitive disorder	0.006	0.994	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.994	0.006
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.994	0.005
G36 Other acute disseminated demyelination	0.000	0.994	0.006
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.994	0.006
S06.9 Intracranial injury, unspecified	0.005	0.994	0.000
B37.0 Candidal stomatitis	0.000	0.994	0.006
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
K70.4 Alcoholic hepatic failure	0.000	0.995	0.005
S06.8 Other intracranial injuries	0.005	0.995	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.995	0.005
S06.00 Concussion (without open intracranial wound)	0.005	0.995	0.000
B37.8 Candidiasis of other sites	0.000	0.995	0.005
M94.88 Other specified disorders of cartilage (Other)	0.005	0.995	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.005	0.995	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.005	0.995	0.000
B37 Candidiasis	0.000	0.995	0.005
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.995	0.005
R60.9 Oedema, unspecified	0.000	0.995	0.005
M88.98 Paget's disease of bone, unspecified (Other)	0.005	0.995	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.005	0.995	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.005	0.995	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.005	0.995	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.005	0.995	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.005	0.995	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.005	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.995	0.001
E21.2 Other hyperparathyroidism	0.000	0.995	0.005
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.995	0.005
B35.3 Tinea pedis	0.000	0.995	0.005
C71.9 Brain, unspecified	0.000	0.995	0.005
K70.9 Alcoholic liver disease, unspecified	0.000	0.995	0.005
S06.01 Concussion (with open intracranial wound)	0.005	0.995	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.005	0.995	0.000
K70 Alcoholic liver disease	0.000	0.995	0.005
B35 Dermatophytosis	0.000	0.995	0.005
S06.3 Focal brain injury	0.005	0.995	0.000
R35 Polyuria	0.005	0.995	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.004	0.995	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.004	0.995	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.004	0.995	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.004	0.995	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.004	0.995	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.004	0.995	0.000
Q27.4 Congenital phlebectasia	0.004	0.995	0.000
Q27.2 Other congenital malformations of renal artery	0.004	0.995	0.000
Q27.1 Congenital renal artery stenosis	0.004	0.995	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.004	0.995	0.000
H73.8 Other specified disorders of tympanic membrane	0.005	0.995	0.000
K86.1 Other chronic pancreatitis	0.005	0.995	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.995	0.005
H73 Other disorders of tympanic membrane	0.005	0.995	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.004	0.995	0.000
B35.1 Tinea unguium	0.000	0.995	0.004
G37.5 Concentric sclerosis [Balo]	0.000	0.996	0.004
G37.4 Subacute necrotising myelitis	0.000	0.996	0.004
G37.2 Central pontine myelinolysis	0.000	0.996	0.004
G37.1 Central demyelination of corpus callosum	0.000	0.996	0.004
G37.0 Diffuse sclerosis	0.000	0.996	0.004
K70.1 Alcoholic hepatitis	0.000	0.996	0.004
E11.4 With neurological complications	0.004	0.996	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.996	0.004
G36.8 Other specified acute disseminated demyelination	0.000	0.996	0.004
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.996	0.004
H66.3 Other chronic suppurative otitis media	0.004	0.996	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.004	0.996	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.996	0.004
B37.2 Candidiasis of skin and nail	0.000	0.996	0.004
H71 Cholesteatoma of middle ear	0.004	0.996	0.000
R39 Other symptoms and signs involving the urinary system	0.004	0.996	0.000
B37.9 Candidiasis, unspecified	0.000	0.996	0.004
R30.0 Dysuria	0.004	0.996	0.000
R47.1 Dysarthria and anarthria	0.000	0.996	0.004
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.004	0.996	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.004	0.996	0.000
B37.1 Pulmonary candidiasis	0.000	0.996	0.004
H73.9 Disorder of tympanic membrane, unspecified	0.004	0.996	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.004	0.996	0.000
B35-B49 Mycoses	0.000	0.996	0.004
S06.81 Other intracranial injuries (with open intracranial wound)	0.004	0.996	0.000
B37.4 Candidiasis of other urogenital sites	0.000	0.996	0.004
G36.0 Neuromyelitis optica [Devic]	0.000	0.996	0.004
M79.67 Pain in limb (Ankle and foot)	0.004	0.996	0.000
E21.4 Other specified disorders of parathyroid gland	0.001	0.996	0.003
H73.0 Acute myringitis	0.004	0.996	0.000
N48.2 Other inflammatory disorders of penis	0.004	0.996	0.000
B37.6 Candidal endocarditis	0.000	0.996	0.004
B37.5 Candidal meningitis	0.000	0.996	0.004
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.996	0.004
D21.0 Connective and other soft tissue of head, face and neck	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations